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Dissertations / Theses on the topic 'Thrombophilia'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Simmonds, Rachel Elizabeth. "Protein S deficiency and familial thrombophilia." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267993.

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2

Beauchamp, Nicholas James. "Molecular genetic basis of inherited thrombophilia." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287349.

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3

Sanson, Bernd-Jan. "Risks of thrombophilia and diagnostics of pulmonary embolism." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/83894.

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4

Lijfering, Willem Marten. "Thrombophilia issue or non-issue in clinical practice? /." [S.l. : [Groningen : s.n.] ; University of Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.

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5

Ibrahim, Ayman Hussein. "The thrombomodulin gene and its contribution to adverse pregnancy outcome." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288113.

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6

Jennings, I. "An investigation of diagnostic errors in laboratory screening for thrombophilia." Thesis, University of Sheffield, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419385.

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7

Folkeringa, Nienke. "Pregnancy-related thrombosis and fetal loss in women with thrombophilia." [S.l. : [Groningen : s.n.] ; University of Groningen] [Host], 2009. http://irs.ub.rug.nl/ppn/.

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8

Pecheniuk, Natalie Maria. "DNA analysis of common genetic variations which predispose to thrombophilia." Thesis, Queensland University of Technology, 2000.

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9

Wakeman, Lisa Jayne. "Whole blood platelet function testing as an adjunct to thrombophilia screening." Thesis, University of the West of England, Bristol, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.601348.

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Platelet hyperaggregability, including Sticky Platelet Syndrome has been identified as a cause of thrombotic conditions including venous thrombosis and foetal loss. The laboratory diagnosis of classical Sticky Platelet Syndrome is based on enhanced platelet aggregation responses to submaximallevels of adenosine diphosphate and epinephrine by optical aggregometry techniques. This study sought to evaluate platelet hyperaggregability by Multiple Electrode Aggregometry, PFA-100 analysis and quantitative analysis of associated platelet parameters as an adjunct to thrombophilia screening. Forty nine

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10

Gomer, Kerry Gretchen. "Women, birth control pills, and thrombophilia an analysis of current risk communication /." Connect to this title online, 2009. http://etd.lib.clemson.edu/documents/1247509090/.

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11

Al, Frouh Fadi. "Analyse des facteurs de risque de maladie thromboembolique veineuse (MTEV) chez les femmes sous contraception oestroprogestative." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0663/document.

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L'objectif de notre première étude était d'identifier les déterminants génétiques et environnementaux du risque de maladie thromboembolique veineuse (MTEV) chez les femmes sous contraceptifs oraux combinés (COC). Après ajustement pour les facteurs confondants, les principaux déterminants environnementaux de la MTEV étaient le tabagisme (OR = 1,65) et un indice de masse corporelle supérieur à 35 kg.m2 (OR = 3,46). En outre, la thrombophilie héréditaire sévère (OR = 2,13) et les groupes sanguins non-O (OR = 1,98). Nous avons confirmé que l’histoire familiale au premier degré de MTEV prédit mal l

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12

Tagalakis, Vasiliki. "The role of inherited thrombophilia in peripheral vein infusion thrombophlebitis : a pilot study." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=79140.

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Background. Peripheral vein infusion thrombophlebitis (PVIT) is a complication of intravenous therapy. We hypothesized that inherited thrombophilia may increase the risk of PVIT.<br>Purpose. In preparation for a multi-center study of our hypothesis, we conducted a pilot study to estimate PVIT incidence, measure the prevalence of inherited thrombophilia, and pilot test the study procedures.<br>Methods. A prospective case-control study of 25 cases (patients with PVIT) matched on catheter duration to 25 controls. PVIT risk factors and inherited thrombophilia were assessed.<br>Results. PVIT

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13

HELLMANN, ELIZABETH ANN. "KNOWLEDGE, HEALTH PERCEPTION AND INFORMATION SATISFACTION OF INDIVIDUALS WITH FACTOR V LEIDEN THROMBOPHILIA." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1022855574.

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14

Martinelli, Ida Marianna. "Clinical studies on hereditary thrombophilia a focus on resistance to activated protein C (factor V:Q506) /." Maastricht : Maastricht : Universiteit van Maastricht ; University Library, Maastricht University [Host], 1997. http://arno.unimaas.nl/show.cgi?fid=5929.

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15

PONTRELLI, GIUSEPPE. "Thrombophilia, systemic inflammation and prevention of cardiovascular disease in children and adolescents with HIV infection." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/1430.

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La malattia aterosclerotica inizia già dalla seconda decade di vita. Insieme ai tradizionali fattori di rischio associati (fumo, colesterolo, ipertensione) negli ultimi anni si è andata caratterizzando il ruolo dell’infiammazione, risultata, da studi di base confermati da numerose osservazioni cliniche, una componente patogenetica rilevante nell’insorgenza e progressione della lesione aterosclerotica. Patologie associate ad infiammazione sistemica come il Lupus Eritematoso o la malattia di Kawasaki sono considerate condizioni a rischio moderato di aterosclerosi in età pediatrica. Anche l’inf

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16

Sastry, Sanjay Dwarakanath. "The role of venous-to-arterial circulation shunts and thrombophilia in ischaemic events in young adults." Thesis, University of Manchester, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493423.

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The cause of myocardial infarction (MI) and ischaemic stroke (IS) in young adults is often uncertain and paradoxical embolism may be more frequent than previously thought. Contrast transcranial Doppler (TCD) is a simple, non-invasive technique for the detection of venous-to-arterial circulation shunts (v-aCS). We investigated the frequency of v-aCS, usually patent foramen ovale (PFO), and thrombophilia in young adults suffering MI and IS and matched healthy controls. We validated our contrast TCD protocol for its reproducibility and by comparison with transoesophageal echocardiography (TOE).

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17

Maleki-Yazdi, Keon. "The genetic determinants of small-for-gestational-age infants in thrombophilia and folate metabolism pathways investigated through meta-analysis." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121509.

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Background: Previous data have demonstrated associations for an increased risk of the small-for-gestational-age (SGA) outcome in offspring of pregnant women with thrombophilia and folate metabolism gene polymorphisms. However, these results have not been consistent.Methods: The objective of this thesis is to review genetic association studies in thrombophilia and folate metabolism pathways for the SGA outcome (defined as birth weight below the 10th percentile for gestational age and sex according to national standards). We performed a series of meta-analyses for commonly studied maternal and n

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18

Mangerona, Lucilene Rossilho [UNESP]. "Trombofilias e abortos recorrentes." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/88102.

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Made available in DSpace on 2014-06-11T19:23:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-02-28Bitstream added on 2014-06-13T19:49:52Z : No. of bitstreams: 1 mangerona_lr_me_botfm.pdf: 551674 bytes, checksum: fa33b5ef943c594fe040a66778a352bd (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Ministério da Saúde<br>Secretaria do Estado da Saúde de São Paulo<br>A perda gestacional recorrente idiopática é multifatorial, pois envolve fatores de risco clínicos e biológicos. A trombofilia pode ser definida como uma predisposição para trombose. Anormalidades na h

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19

Taniguchi, Adriano Nori Rodrigues. "Características clínico-laboratoriais de pacientes pediátricos com tromboembolismo." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/110193.

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Objetivo: Avaliar a incidência de tromboembolismo e as condições clínicolaboratoriais associadas em pacientes pediátricos internados em um hospital terciário. Pacientes e métodos: Estudo retrospectivo onde foram revisados os prontuários de todas as 6140 crianças de 0 à 13 anos que internaram entre fevereiro de 2007 à janeiro de 2009. Foram identificadas 31 crianças que tiveram 34 casos de tromboembolismo confirmado por diagnóstico de imagem, e estas foram incluídas no banco de dados para análise. Resultados: A incidência de tromboembolismo foi de 43,3 (intervalo de confiança de 95%: 30,0-60,4)

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20

Boama, Vincent. "Prevalence of known thrombophilia and incidence of venous thromboembolism in pregnant woment in the Western Cape Province of South Africa." Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/3031.

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Includes bibliographical references (leaves 29-32).<br>Venous thromboembolism (VTE) is a major cause of maternal mortality worldwide. In many developed countries, all maternal deaths are investigated, and accurate statistics are available. In United Kingdom (UK) for example, VTE is the leading cause- and is increasing despite heightened awareness of risk factors, and wider use of thromboprophylaxis (1,2). The 1994-96 UK Confidential Enquiries reported an overall maternal mortality rate of 12.2 per 100, 000 deliveries, with specific mortality from VTE at 2.2 per 100, 000 deliveries, with approx

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Järvenpää, J. (Jouko). "Placental angiogenesis and angiogenesis related risk factors in severe pre-eclampsia." Doctoral thesis, University of Oulu, 2008. http://urn.fi/urn:isbn:9789514288760.

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Abstract The incidence of pre-eclampsia (PE) is 2–7% in different populations and in the worst cases PE may threaten the survival of both mother and newborn; its pathogenesis is not resolved. Field literature today considers PE an angiogenic disorder. Coordinated vascularization is essential for placental development. We wanted to find novel factors in the etiology of PE, and focused our attention on angiogenesis, inherited thrombophilia and folate-homocysteine metabolism. Homocysteine inhibits endothelial cell proliferation, which is closely related to angiogenesis. We performed gene express

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22

Carvalho, Eunice BobÃ de. "DetecÃÃo do fator V Leiden em pacientes trombofÃlicos no Estado do CearÃ." Universidade Federal do CearÃ, 2004. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=2698.

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nÃo hÃ<br>As doenÃas trombÃticas constituem um sÃrio problema na saÃde mundial. Diversas desordens hereditÃrias, que afetam o sistema fisiolÃgico anticoagulante, estÃo atualmente estabelecidas como fatores de risco para a ocorrÃncia do evento trombÃtico. Dentre estes o fator V Leiden Ã o mais freqÃente. A associaÃÃo entre alteraÃÃes no gene do fator V e a ocorrÃncia de eventos trombÃticos desencadeou o desenvolvimento de diversas pesquisas. Neste estudo, 100 pacientes portadores de eventos trombÃticos, atendidos no ambulatÃrio de Hematologia do Centro de Hematologia e Hemoterapia do CearÃ - HE

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23

Karttunen, V. (Vesa). "Patent foramen ovale and cryptogenic brain infarction." Doctoral thesis, University of Oulu, 2002. http://urn.fi/urn:isbn:9514267435.

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Abstract Patent foramen ovale (PFO) is a common finding in the general population and is present in approximately one quarter of adults. The potential role of PFO in the pathogenesis of ischaemic brain infarction of unknown aetiology in young adults has been investigated during the past 15 years, and associations with other diseases have been proposed. The most plausible mechanism of stroke associated with PFO is paradoxical embolism, but there is uncertainty about this because a venous source of emboli is seldom identified. If the theory of venous emboli is relevant, prothrombotic states shou

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24

Tófano, Viviane Alessandra Capelluppi [UNESP]. "Avaliação clínica e ultrassonografia tardia de pacientes com trombose venosa profunda, portadores de trombofilia." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/103481.

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Made available in DSpace on 2014-06-11T19:32:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-11-14Bitstream added on 2014-06-13T21:04:42Z : No. of bitstreams: 1 tofano_vac_dr_botfm.pdf: 984641 bytes, checksum: d4fcddf13acc4d52c783e4c30966c9b0 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>A trombose venosa profunda (TVP) caracteriza-se pela formação aguda de um trombo no interior das veias profundas. É uma doença de alta incidência e de grande importância clínica e epidemiológica devido à sua morbimortalidade, sendo atualmente, considerada multifato

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25

Rades, Érica. "Investigação de trombofilias em gestantes de risco para o parto prematuro." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/5/5139/tde-28012008-111631/.

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Introdução: O parto prematuro espontâneo é doença multifatorial e sua etiologia permanece desconhecida em até 40% das vezes. Neste estudo, investigamos a existência de trombofilias maternas adquiridas e hereditárias em gestantes de risco para o parto prematuro espontâneo e as relacionamos com a incidência de prematuridade na gestação. Métodos: Neste estudo prospectivo, realizado entre julho de 2004 e setembro de 2006, foram pesquisadas 66 gestantes com antecedente de parto prematuro espontâneo e 66 gestantes sem antecedente de complicações, com pelo menos um parto a termo anterior. Até 25 sema

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26

Ghisdal, Lidia. "Study of several acquired and genetic factors in relation with outcome in kidney transplantation." Doctoral thesis, Universite Libre de Bruxelles, 2012. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209606.

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Introduction et buts de la thèse<p>La survie du patient et du greffon se sont nettement améliorées depuis les débuts de la transplantation rénale. Les recommandations de pratiques cliniques basées sur l’évidence aident les cliniciens à améliorer la prise en charge standardisée des patients. Cependant, de nombreux programmes de recherche sont actuellement axés sur la découverte de biomarqueurs qui peuvent prédire les différents résultats chez les patients transplantés rénaux. Ces biomarqueurs sont nécessaires pour personnaliser la gestion et le traitement des patients.<p>Le but des travaux résu

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27

Mangerona, Lucilene Rossilho. "Trombofilias e abortos recorrentes /." Botucatu : [s.n.], 2007. http://hdl.handle.net/11449/88102.

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Orientador: Izolete Aparecida Thomazini Santos<br>Banca: Paulo Eduardo de Abreu Machado<br>Banca: Márcia Aparecida Sperança<br>Resumo: A perda gestacional recorrente idiopática é multifatorial, pois envolve fatores de risco clínicos e biológicos. A trombofilia pode ser definida como uma predisposição para trombose. Anormalidades na hemostasia que estão associadas com trombofilias clínicas incluem defeitos hereditários, tais como os anticoagulantes naturais Antitrombina III, Proteína S e Proteína C ou fatores de coagulação, as mutações do fator V Leiden, gene da protrombina G20210A, metilenotet

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28

Dunn, Crystal R. "An exploratory study of the psychological and behavioural impacts of genetic testing for thrombophilia among asymptomatic first-degree relatives of patients with venous thrombosis." Thesis, University of Ottawa (Canada), 2006. http://hdl.handle.net/10393/27241.

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Objective. To conduct a preliminary exploration of psychological outcomes and health behaviour in individuals undergoing testing for genetic mutations associated with thrombophilia. Methods. Subjects were 57 carriers and 54 non-carriers identified through an existing pilot study. Part I analyzed perceived risk and psychological data collected at baseline, 1 week and 12 months post-test. Part II used a cross-sectional survey to collect data regarding: test implications, perceived causes and control, and behaviour change post-test. Results. Accuracy of risk perception improved post-test due to d

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29

Castellano, Chiodo Danilo. "Stroke ischemico arterioso perinatale: valutazione clinica e dei fattori di rischio associati." Doctoral thesis, Università di Catania, 2012. http://hdl.handle.net/10761/1203.

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Con un'incidenza che varia da 1/2800 a 1/5000 nati vivi, lo stroke ischemico arterioso perinatale è la più frequente forma di infarto cerebrale in età pediatrica. Il 40% dei pazienti non presentano sintomi specifici nel periodo neonatale e la diagnosi viene posta tardivamente per l'insorgenza di problemi motori, convulsioni, deficit cognitivi o del linguaggio. Il restante 60% dei neonati presenta sintomi precoci, generalmente convulsioni nei primi tre giorni di vita. Lo studio retrospettivo analizza gli aspetti clinici ed i fattori di rischio genetici ed acquisiti associati in una casistica di

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Tófano, Viviane Alessandra Capelluppi. "Avaliação clínica e ultrassonografia tardia de pacientes com trombose venosa profunda, portadores de trombofilia /." Botucatu : [s.n.], 2008. http://hdl.handle.net/11449/103481.

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Orientador: Francisco Humberto de Abreu Maffei<br>Banca: Hamilton Almeida Rollo<br>Banca: Adilson F. Paschôa<br>Banca: Newton Key Hokama<br>Banca: Cyrillo C. Filho<br>Resumo: A trombose venosa profunda (TVP) caracteriza-se pela formação aguda de um trombo no interior das veias profundas. É uma doença de alta incidência e de grande importância clínica e epidemiológica devido à sua morbimortalidade, sendo atualmente, considerada multifatorial. São vários os fatores de risco genéticos e/ou adquiridos relacionados à TVP e a compreensão da interação destes, permite melhor entender esta doença, não

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31

Bouvier, Sylvie. "Nouveaux acteurs moléculaires de la dysfonction vasculo-placentaire." Thesis, Montpellier 1, 2014. http://www.theses.fr/2014MON13505.

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La grossesse est une période de majoration du risque vasculaire, participant à une morbi-mortalité maternelle et fœtale pouvant justifier des mesures de prévention primaire et secondaire. Notre travail évalue l'impact de certains déterminants et l'apport de nouveaux acteurs moléculaires impliqués dans la dysfonction vasculo-placentaire. Le but ultime étant d'optimiser les prises en charge et de développer de nouvelles stratégies thérapeutiques. Nous avons étudié les complications vasculaires placentaires associées à des marqueurs biologiques connus : mutation du facteur V Leiden, mutation du g

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Paschoa, Adilson Ferraz. "Impacto da pesquisa laboratorial de trombofilia na prevençao secundaria e orientação dos doentes com troboembolismo venoso." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310501.

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Orientador: Ana Terezinha Guillaumon<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-07T00:25:35Z (GMT). No. of bitstreams: 1 Paschoa_AdilsonFerraz_D.pdf: 1209751 bytes, checksum: 841d1a79e90d1ef1c6bb14b58b807236 (MD5) Previous issue date: 2006<br>Resumo: O tromboembolismo venoso (TEV) afeta de 1 a 3 indivíduos por mil habitantes/ano. O conhecimento atual das trombofilias permite a associação com cerca de 40% dos casos de TEV. Há controvérsias quanto ao valor da pesquisa laboratorial de trombofilia para o benefício

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Tromeur, Cécile. "Etude des facteurs de risque cliniques de maladie veineuse thromboembolique chez les femmes : implication sur la réduction des risques liées à la stratégie diagnostique de l'embolie pulmonaire chez les femmes enceintes." Thesis, Brest, 2018. http://www.theses.fr/2018BRES0021/document.

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Introduction: La stratégie diagnostique de l’EP au cours de la grossesse est incertaine du fait du manque d’études solides d’un point de vue méthodologique, et du risque lié à l’irradiation des examens diagnostiques (angioscanner thoracique et scintigraphie pulmonaire). L’enjeu est donc de valider des stratégies performantes d’une part, et d’identifier des marqueurs cliniques permettant de réduire le recours aux examens irradiants d’autre part. Notre premier objectif a été d’identifier les pièges au cours de la stratégie diagnostique de l’EP (baisse de la performance du dosage des D‐dimères, d

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Simoni, Renata Zaccaria 1972. "Trombofilia hereditária em fetos com malformações de origem vascular = Genetic polymorphisms in fetuses with malformations of vascular origin." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309004.

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Orientador: Egle Cristina Couto de Carvalho<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T14:08:16Z (GMT). No. of bitstreams: 1 Simoni_RenataZaccaria_D.pdf: 2332845 bytes, checksum: fc29ed8709fbdf31408d1968e76a01a0 (MD5) Previous issue date: 2012<br>Resumo: Contexto e objetivo: Algumas malformações congênitas têm origem vascular, e a trombose durante a organogênese já foi aventada como possível mecanismo para esta ocorrência. O objetivo deste estudo foi avaliar a associação entre trombofilia fetal e malformaçõ

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Souza, Gleice Regina de 1990. "Avaliação in vitro dos efeitos do Heme livre sobre ativação da coagulação e sobre a quebra de barreira endotelial." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309164.

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Orientador: Erich Vinicius de Paula<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-25T23:01:14Z (GMT). No. of bitstreams: 1 Souza_GleiceReginade_M.pdf: 1983428 bytes, checksum: 435b8d4ea1f6b2d6d8254be7fd9c00b2 (MD5) Previous issue date: 2014<br>Resumo: Há cerca de 50 anos sabe-se que pacientes com anemia falciforme (AF) apresentam maiores concentrações plasmáticas de heme livre. Recentemente, foi demonstrado que o heme é capaz de ativar a resposta imune inata, desencadeando resposta dependente de receptores

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Daubner, Ursula [Verfasser]. "Thrombophilie und Schlaganfall / Ursula Daubner." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2013. http://d-nb.info/1064099165/34.

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Soligo, Adriana de Goes e. Silva 1974. "Prevalencia dos fatores trombofilicos em mulheres com infertilidade." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311746.

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Orientadores: Ricardo Barini, Egle Cristina Couto de Carvalho<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-08T19:49:25Z (GMT). No. of bitstreams: 1 Soligo_AdrianadeGoeseSilva_M.pdf: 464907 bytes, checksum: c9378bf0a2d1fe337908abb53f773dbe (MD5) Previous issue date: 2007<br>Resumo: Objetivo: determinar a prevalência dos fatores trombofílicos em mulheres inférteis. Método: estudo de corte transversal, no qual foram admitidas mulheres inférteis (atendidas em clínica privada) e submetidas à investigação de tro

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Lopes, Michelle Remião Ugolini. "Assinatura de interferon tipo I na síndrome antifosfolípide primária." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5140/tde-05122018-125757/.

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Introdução: a síndrome antifosfolípide (SAF) primária é uma vasculopatia autoimune mediada por autoanticorpos com trombose como sua principal manifestação clínica. A presença de anticorpos antifosfolípides (aPL), embora relevante para confirmar o diagnóstico, não parece ser suficiente para explicar completamente a fisiopatologia da doença e um segundo gatilho é usualmente necessário. Além das hipóteses de infecções virais e insulto inflamatório como possíveis desencadeantes, parece que os receptores toll like (TLR) e o Interferon (IFN) tipo I são possíveis protagonistas nesse processo, contrib

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Jivraj, Shehnaaz. "Genetic thrombophilic mutations and recurrent miscarriage." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486914.

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Recurrent miscarriage (RM) affects 1% of the population. Some cases have a thrombotic aetiology. While it is known that the allele frequency of factor V Leiden (FVL), a thrombophilic gene mutation, is similar between women with and without RM, the miscarriage rate of a subsequent untreated pregnancy is significantly higher in RM women carrying FVL. The studies in the thesis explore the hypothesis that (a) women with FVL and RM, who went on to miscarry again may have an additional thrombophilia that increased their risk of miscarriage (b) thrombophilia genotype inherited by the fetus may determ

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Baptista, Fernanda Spadotto. "Associação da presença de trombofilias com resultados maternos e fetais em pacientes com formas graves de pré-eclâmpsia." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5139/tde-04012018-082306/.

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OBJETIVO: Avaliar se as trombofilias pioram os desfechos maternos e fetais entre pacientes com formas graves de pré-eclâmpsia (PE). MÉTODO: De outubro/2009 a outubro/2014, foi realizada uma coorte retrospectiva de gestantes com PE grave diagnosticada antes de 34 semanas e seus recém-nascidos (RNs), internados no Hospital das Clínicas da FMUSP. Foram incluídas pacientes que tinham ausência de cardiopatias, nefropatias, diabetes pré-gestacional, moléstia trofoblástica gestacional, malformação fetal, gemelidade e que realizaram pesquisa de trombofilias no período pós-natal. Foram excluídas gestaç

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Glaum, Ricarda. "Giessener Thrombophiliestudie eine retrospektive Analyse /." Wettenberg : VVB Laufersweiler, 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972521755.

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Voetsch, Barbara. "Inherited thrombophilias among young patients with ischemic stroke." [s.n.], 2002. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308456.

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Orientadores: Benito Pereira Damasceno, Valder Roberval Arruda<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-02T22:17:13Z (GMT). No. of bitstreams: 1 Voetsch_Barbara_D.pdf: 55176396 bytes, checksum: f274efe61664e0541b7ed17b893440eb (MD5) Previous issue date: 2002<br>Resumo: Introdução e Objetivo: A etiologia de acidentes vasculares cerebrais isquêmicos (AVCi) em pacientes jovens permanece desconhecida em um terço dos casos, justificando a procura por novos fatores de risco protrombóticos. Causas comuns de trombof

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Peleska, Gerhard. "Komplikationen der Behandlung mit Kumarin-Derivaten und Ergebnisse einer modifizierten Dosisanpassung : Pilotstudie aus einer ärztlichen Praxis /." Marburg : Görich & Weiershäuser, 2009. http://d-nb.info/994710666/04.

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Groussin, Sophie Lecompte Thomas. "Première consultation de contraception et prévention des accidents thromboemboliques veineux sous estroprogestatifs expérience d'un centre de planification /." [S.l.] : [s.n.], 2008. http://www.scd.uhp-nancy.fr/docnum/SCDMED_T_2008_GROUSSIN_SOPHIE.pdf.

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Gentilomo, Chiara. "Studio della trombosi infantile mediante la realizzazione e l'utilizzo di un registro nazionale per la raccolta dei casi di trombosi cerebrale e sistemica in età pediatrica e neonatale e valutazione della trombofilia." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422183.

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SECTION 1: THE ITALIAN REGISTRY OF CHILDHOOD THROMBOSIS BACKGROUND: Thromboembolism (TE) in children is a growing problem, more frequent than previously thought. A recent survey performed in 40 pediatric tertiary care hospitals of th e US shows an increase of 70% (34 to 58 cases per 100 admissions from 2001 to 2007). Many cases still remain unrecognized or lately diagnosed, worsening the prognosis. The prognosis of pediatric TE is severe both for mortality and morbidity rate, especially as for as cerebral stroke is concerned. Epidemiological data as well as pediatric randomized clinical tri

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Herz-Bergemann, Katharina [Verfasser]. "Thrombophilie in der Schwangerschaft : Schwangerschaftskomplikationen und therapeutische Möglichkeiten / Katharina Herz-Bergemann." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2012. http://d-nb.info/1030381275/34.

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Herz-Bergemann, Katharina Maria [Verfasser]. "Thrombophilie in der Schwangerschaft : Schwangerschaftskomplikationen und therapeutische Möglichkeiten / Katharina Herz-Bergemann." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2012. http://d-nb.info/1030381275/34.

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Sarno, Manoel Alfredo Curvelo. "Associação entre antecedentes morbidos, dopplervelocimetria de arterias uterinas, anticorpos antifosfolipideos e resultados perinatais adversos em um grupo de gestantes." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311741.

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Orientador: Ricardo Barini<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-12T18:24:38Z (GMT). No. of bitstreams: 1 Sarno_ManoelAlfredoCurvelo._D.pdf: 2031340 bytes, checksum: 3b2a7d30a8001e19edce044e6d8670ab (MD5) Previous issue date: 2009<br>Resumo: Introdução: A presença de anticorpos antifosfolipídeos freqüentemente está associada a complicações obstétricas como aborto de repetição, óbito fetal, descolamento prematuro da placenta e pré-eclâmpsia grave e precoce. Objetivo: avaliar associação dos antecedentes mór

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Buzluca-Dargaud, Gamze Yesim. "Phénotypage du système de coagulation sanguine par la mesure de génération de thrombine : étude pré-clinique et applications cliniques innovantes." Lyon 1, 2006. http://www.theses.fr/2006LYO10122.

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L'exploration de l'hémostase est basée sur la mesure des temps de coagulation ou des activités des différentes protéines de la coagulation. Cette approche a une faible valeur prédictive du risque individuel hémorragique ou thrombotique encouru par les patients. Nous avons étudié le test de génération de thrombine pour le phénotypage de la coagulation. Les conditions préanalytiques et analytiques permettant de s'approcher le plus possible des conditions physiologiques ont été déterminées avec une bonne répétabilité, reproductibilité du test permettant son utilisation dans des laboratoires hospi

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Membre, Aurélie Regnault Véronique. "Hypercoagulabilité associée aux anticorps anti-phospholipides approches descriptives et mécanistiques /." S. l. : Nancy 1, 2008. http://www.scd.uhp-nancy.fr/docnum/SCD_T_2008_0125_MEMBRE.pdf.

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