Academic literature on the topic 'Thrombose de stent'

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Journal articles on the topic "Thrombose de stent"

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Gellen, B., and E. Teiger. "Thrombose de stent." Archives des Maladies du Coeur et des Vaisseaux - Pratique 2011, no. 196 (2011): 31–34. http://dx.doi.org/10.1016/s1261-694x(11)70202-4.

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Kallel, R., R. Hakim, and G. Rangé. "Thrombose de stent : quoi de neuf en 2017 ?" Annales de Cardiologie et d'Angéiologie 66, no. 6 (2017): 393–99. http://dx.doi.org/10.1016/j.ancard.2017.10.007.

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Huhle, G., S. Lessmann, U. Hoffmann, et al. "Langzeitantikoagulation bei Patienten mit Leberzirrhose und Implantation eines transjugulären, intrahepatischen portosystemischen Shunts." Hämostaseologie 20, no. 02 (2000): 107–9. http://dx.doi.org/10.1055/s-0037-1619475.

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ZusammenfassungDie Patienten mit Leberzirrhose und den Komplikationen einer portalen Hypertension erhalten zunehmend einen transjugulären, intrahepatischen portosystemischen Stent Shunt (TIPSS). Studien haben den Wert dieser Behandlung zur Rezidivprophylaxe von Ösophagusvarizenblutungen und einem therapieresistenten Aszites belegt. Die Limitierung einer Implantation eines TIPSS besteht jedoch in der Ausbildung von Stent-Thrombosen oder -Stenosen. Azetylsalizylsäure ist nicht erfolgreich in der Prophylaxe der Stent-Thrombose. Phenprocoumon führt hingegen zu einer signifikanten Offenheitsrate. O
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Lemesle, G., and C. Delhaye. "La thrombose de stent, de plus en plus rare !" Annales de Cardiologie et d'Angéiologie 60, no. 6 (2011): 338–46. http://dx.doi.org/10.1016/j.ancard.2011.09.001.

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Grivel, Thierry. "Quels sont les facteurs de risque de thrombose de stent ?" Option/Bio 19, no. 399 (2008): 6. http://dx.doi.org/10.1016/s0992-5945(08)70112-0.

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Kaptein, Yvonne E. "Acute ST-elevation myocardial infarction due to in-stent thrombosis after administering tranexamic acid in a high cardiac risk patient." BMJ Case Reports 12, no. 4 (2019): e227957. http://dx.doi.org/10.1136/bcr-2018-227957.

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Tranexamic acid (TXA) is an antifibrinolytic which minimises bleeding and transfusions, with thrombotic risk. Our patient had known coronary artery disease with post-TXA acute ST-elevation myocardial infarction (STEMI) due to in-stent thrombosis. He had five drug-eluting stents (DES): two overlapping DES in mid-LAD (3 years ago), and two overlapping DES in distal right coronary artery and one DES in obtuse-marginal (1.5 years ago). After TXA, both overlapping stent locations thrombosed. Of nine reports of post-TXA acute MI, only one had complex stent anatomy (bifurcation stent to left circumfl
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Leithäuser and Park. "Endovascular treatment of an occluded popliteal aneurysm with locoregional thrombolysis followed by stent graft exclusion." Vasa 38, no. 1 (2009): 85–90. http://dx.doi.org/10.1024/0301-1526.38.1.85.

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Popliteal artery aneurysms can thrombose or cause distal embolization and are therefore potentially limb-threatening lesions. This report describes the case of a 70-year-old man with severe claudication due to a thrombosed aneurysm of the left popliteal artery. He gave consent for a locoregional thrombolytical therapy, but refused standard surgical treatment. Thus, we developed the idea to restore blood flow by means of thrombolysis first, and then to perform a definitive repair of the aneurysm after a period of time. After successful thrombolysis and after 14 days as an outpatient with weight
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Rangé, G., R. Hakim, C. Saint Etienne, et al. "Thrombose de stent : une bataille gagnée ? (Données du registre France PCI)." Annales de Cardiologie et d'Angéiologie 70, no. 6 (2021): 388–94. http://dx.doi.org/10.1016/j.ancard.2021.10.001.

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Torre, Joanne, Mazen Hashisho, Cheng Lo, and Eugene Mohan. "Thrombose aiguë d’un stent de l’artère rénale et rein unique fonctionnel." Annales de Chirurgie Vasculaire 24, no. 7 (2010): 1037.e7–1037.e13. http://dx.doi.org/10.1016/j.acvfr.2011.02.027.

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Nelson, Peter R., and W. Anthony Lee. "Endovascular Treatment Of Popliteal Artery Aneurysms." Vascular 14, no. 5 (2006): 297–304. http://dx.doi.org/10.2310/6670.2006.00049.

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Popliteal artery aneurysms are relatively uncommon but potentially limb-threatening lesions that can thrombose or cause distal embolization. Identification of these aneurysms, especially in patients with abdominal aortic aneurysms, is imperative, and prophylactic treatment with either surgical exclusion and bypass or endoluminal stent grafting is critical to prevent these poor outcomes. Endovascular approaches currently using the Viabahn stent graft offer several advantages, including a minimally invasive approach, fewer perioperative complications, and a faster recovery. This must be balanced
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Dissertations / Theses on the topic "Thrombose de stent"

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Kern, Axelle Y. "La thrombose de stent : évaluation de l’importance de la rhéologie dans la thrombogénicité des stents et d’un nouvel agent pharmacologique dirigé contre la GPVI pour prévenir la thrombose de stent." Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAJ027.

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Une complication majeure de la pose d’un stent sur une plaque d’athérosclérose est la thrombose de stent, qui présente un taux de mortalité particulièrement élevé. La bithérapie antiplaquettaire, indiquée dans la prévention de cette complication, entraîne un risque important de saignement et n’est pas toujours efficace. L’objectif de ce travail de thèse a consisté à identifier les mécanismes de la thrombose de stent et à évaluer l’intérêt d’une nouvelle classe d'agents antiplaquettaires capables de la prévenir efficacement avec un risque hémorragique faible. Le développement d’un modèle macrof
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Bonello, Laurent. "Nouveaux bio-marqueurs predictifs de la thrombose et de la restenose chez les patients coronariens traites parangioplastie coronaire avec implantation d'une endoprothèse." Thesis, Aix-Marseille 2, 2011. http://www.theses.fr/2011AIX22954.

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L’angioplastie coronaire est la première forme de revascularisation coronaire. Elle présente cependant 2 limites qui restreignent encore son utilisation : la thrombose et la resténose de stent. La thrombose de stent est un événement précoce associé à une mortalité élevée. Les plaquettes y jouent un rôle déterminant. Le développement de tests fonctionnels plaquettaires permettant d’analyser le niveau de réactivité plaquettaire sous traitement a permis de mettre en évidence les limites de celui-ci sur le plan biologique. Nous avons démontré l’impact clinique de l’utilisation de ces tests dans la
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Kersani, Dyhia. "Recouvrement de stents vasculaires par electrospinning pour la prévention de la resténose et la thrombose." Thesis, Lille 1, 2019. http://www.theses.fr/2019LIL1R082.

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Les maladies cardiovasculaires représentent la première cause de mortalité dans les pays développés. Ces maladies ont pour étiologie l’athérosclérose, une pathologie artérielle provoquée par l’accumulation de dépôts lipidiques sur la paroi de l’artère engendrant une obstruction partielle (sténose) ou totale de l’artère (thrombose). L’angioplastie avec pose de stent élué de principe actif antiprolifératif ou anti-inflammatoire est le traitement de référence pour lutter contre ces pathologies, qui sont les principales causes d’infarctus du myocarde et d’accidents vasculaires cérébraux. Cependant
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Delattre, Cécilia. "Mise au point et évaluation de nouveaux revêtements de stents pour application cardio-vasculaire." Thesis, Sorbonne Paris Cité, 2015. http://www.theses.fr/2015USPCD061/document.

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L’objectif de ce travail est d’évaluer la biocompatibilité d’un copolymère de Dextrane- Polybutylmethacrylate utilisé comme revêtement de stent métallique en Cobalt-Chrome. L’étude s’est déroulée en trois phase : 1/La production du polymère et la caractérisation physico-chimique, 2/L’évaluation in vitro et 3/L’évaluation in vivo dans plusieurs modèles. Dans un premier temps deux copolymères de concentrations distinctes ont été synthétisés et mis en forme pour les différentes expériences. Leur caractérisation par FTIR, mesure d’angle de contact et une première implantation in vivo évaluant la r
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Sobocinski, Jonathan. "Fonctionnalisation de stents vasculaires par des matrices polymères contenant des molécules bioactives." Phd thesis, Université du Droit et de la Santé - Lille II, 2013. http://tel.archives-ouvertes.fr/tel-01019703.

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Ce projet de thèse concerne les 2 principales complications rencontrées en pratique clinique dans les suites de l'angioplastie-stenting artériel : la resténose et la thrombose aigüe. Pour remédier à ce problème, des stents enrobés d'agents antiprolifératifs sont déjà sur le marché, mais leurs résultats restent décevants en raison de l'augmentation du taux de thrombose tardive intrastent (RR 1,2 vs stent nu) à l'origine d'une surmortalité (RR 1,32 vs stent nu) [Lagerqvist Bo et al., N Eng J Med 2007]. Dans ce travail, nous proposons d'immobiliser sur le stent une ancre spécifique au substrat mé
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Chabi, Fatiha. "Etude numérique et expérimentale du transfert de masse, par advection et diffusion en écoulement pulsé, sur des stents actifs." Thesis, Paris, ENSAM, 2016. http://www.theses.fr/2016ENAM0051/document.

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La perturbation des écoulements au voisinage de la paroi artérielle équipée d'un stent joue un rôle prépondérant dans l'apparition et le développement des complications liées aux maladies cardiovasculaires (sténose, resténose, thrombose...). La topologie de l'écoulement dans ces régions est très complexe. En effet, au voisinage du stent, des zones de recirculation se forment en amont et aval de chaque branche et les contraintes pariétales y sont très faibles. Des études in vivo et in vitro ont mis en évidence le rôle de ces caractéristiques de l'écoulement intra-stent sur les maladies cardiova
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Yamaji, Kyohei. "Bare-metal Stent Thrombosis and In-stent Neoatherosclerosis." Kyoto University, 2012. http://hdl.handle.net/2433/158059.

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El, Ghannudi-Abdo Soraya. "Déterminants de l'athérothrombose chez le patient diabétique de type II." Thesis, Strasbourg, 2013. http://www.theses.fr/2013STRAJ041.

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L’athérothrombose représente 80% des causes de décès chez les patients diabétiques de type II (DM-II). L’objectif de ce travail est d’étudier les déterminants de l’athérothrombose chez le patient DM-II : (I) étude de l’inhibition des fonctions plaquettaires par le clopidogrel chez le patient DM-II: cette première partie du travail est centrée sur : l’impact du DM-II sur la qualité de l’inhibition plaquettaire par le clopidogrel, l’impact clinique de cette inhibition insuffisante (LR) des fonctions plaquettaires par le clopidogrel en terme d’évènements cardiovasculaires majeurs après angioplast
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Rouchaud, Aymeric. "Optimisation biologique du traitement endovasculaire des anévrysmes intracrâniens." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCD046/document.

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La genèse d’un anévrysme intracrânien n’est pas uniquement due à un effet mécanique mais à un ensemble d’éléments biologiques. Parmi eux, le thrombus intra-anévrysmal a un rôle majeur car il est le site d’activation de nombreuses métalloprotéinases et d’une protéolyse importante. Cependant, le thrombus du sac anévrysmal est également un substrat indispensable à la cicatrisation des anévrysmes après traitement endovasculaire car il sert de support à la recolonisation de l’anévrysme par des cellules mésenchymateuses. Dans les différents travaux présentés dans cette thèse, nous avons pu analyser
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Ong, Andrew Teck Leong. "The unrestricted use of paclitaxel-eluting stents and eirolimus-eluting stents in the Rotterdam T-SEARCH and RESEARCH Registries: Studies on efficacy, safety, stent thrombosis, cost eff ectiveness and the future." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/10526.

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Books on the topic "Thrombose de stent"

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W, Serruys P., ed. Coronary lesions: A pragmatic approach. Martin Dunitz, 2002.

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Stent thrombosis: Epidemiology, prevention, and management. Nova Science, 2011.

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Kahn, S. Lowell. Creation of a Flow-Modulating Stent Using Multilayered Wallstents for Aneurysm Exclusion. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0011.

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Abdominal aortic aneurysms (AAAs) are a common pathology that is found in 4–9% of patients in the developed world. Risk factors for AAAs include age, male sex, family history, comorbid cardiovascular disease, and smoking. Despite the male predominance of the disease, rupture occurs at a smaller diameter in females, and the outcomes are poorer in this subgroup. Flow-modulating stents are a relatively new development and consist of multilayered bare-metal self-expanding stents. Despite the inherent porosity of the stents, the interconnected stent matrix features flow-diverting properties that pr
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Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_002.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following: All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hours. Patients with very high-risk non-ST-segment elevation acute coronary syndromes (re
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Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_003.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following: All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hours. Patients with very high-risk non-ST-segment elevation acute coronary syndromes (re
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Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0047.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following:All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hoursPatients with very high-risk non-ST-segment elevation acute coronary syndromes (recur
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Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_001.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following:All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hoursPatients with very high-risk non-ST-segment elevation acute coronary syndromes (recur
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Kahn, S. Lowell. Branched Stent Graft Placement in the Vena Cava Using the Endologix AFX. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0031.

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Superior vena cava syndrome (SVCS) comprises a constellation of symptoms resulting from stenosis, occlusion, or thrombosis of the SVC of benign and malignant etiologies. The diagnosis is most commonly seen with thoracic malignancies, with primary lung cancer accounting for up to 70% of cases. Up to 4% of lung cancer patients present with SVCS at the time of diagnosis, and many more develop it at a later time. In younger patients with SVCS, lymphoma is commonly responsible. Recently, there has been a rise in benign SVCS secondary to the increased use of central venous catheters and pacemakers.
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Colombo, Antonio, Patrick W. Serruys, Michael J. B. Kutryk, and Martin B. Leon. Coronary Lesions: A pragmatic approach. Informa Healthcare, 2001.

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Serruys, Patrick W., Martin B. Leon, Antonio Colombo, and Michael J. B. Kutryk. Coronary Lesions: Pragmatic Approach. Taylor & Francis Group, 2001.

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Book chapters on the topic "Thrombose de stent"

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Guagliumi, Giulio, Chiara Bernelli, Kenichi Komukai, and Vasile Sirbu. "Stent Thrombosis." In Cardiovascular OCT Imaging. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-10801-8_11.

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Cuesta, Javier, Marcos García-Guimaraes, Fernando Rivero, Teresa Bastante, and Fernando Alfonso. "Stent Thrombosis." In The Interventional Cardiology Training Manual. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-71635-0_22.

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Souteyrand, Geraud, Nicolas Combaret, Nicolas Amabile, and Pascal Motreff. "Coronary Stent Thrombosis." In Textbook of Catheter-Based Cardiovascular Interventions. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-55994-0_59.

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Kini, Annapoorna, Jagat Narula, Yuliya Vengrenyuk, and Samin Sharma. "Post-Stent Evaluation, Stent Thrombosis, and In-Stent Restenosis." In Atlas of Coronary Intravascular Optical Coherence Tomography. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62666-6_4.

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Adriaenssens, Tom. "Very Late Stent Thrombosis." In Cardiovascular OCT Imaging. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-25711-8_10.

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McCullough, S. Andrew, and George D. Dangas. "Stent thrombosis and restenosis." In Practical Interventional Cardiology. CRC Press, 2017. http://dx.doi.org/10.1201/9781315113753-14.

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Gupta, Vipul. "Acute Thrombosis of Carotid Stent." In 100 Interesting Case Studies in Neurointervention: Tips and Tricks. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-1346-2_98.

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Hans, Sachinder Singh. "Management of Iliac Stent Thrombosis." In Challenging Arterial Reconstructions. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44135-7_89.

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Mahmoudi, Michael, and Ron Waksman. "Coronary Bifurcation Stenting and Stent Thrombosis." In Bifurcation Stenting. John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781444347005.ch10.

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Berek, K., and F. Aichner. "Wo steht die Thrombolyse beim Schlaganfall heute?" In Schlaganfall. Springer Vienna, 1996. http://dx.doi.org/10.1007/978-3-7091-7480-7_28.

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Conference papers on the topic "Thrombose de stent"

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Welch, Tre R., Robert C. Eberhart, and Cheng-Jen Chuong. "Thermal Treatment Effects Upon the Degradation Characteristics of PLLA Coiled Stents." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206884.

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Stents are a medical device used to restore blood flow in stenosed vessels. During the process of stent expansion, the balloon and stent could damage the endothelial lining of the vascular wall and alter the mechanical stress states of various tissue components. The evolution of stents has progressed from bare metal stents to drug eluting stents or stents coated with drugs such as Sirolimus. Drug eluting stents are currently used to address the restenosis event that occurs after implantation. These stents have been effective but late stent thrombosis has been an emerging issue with drug elutin
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Wang, Longzhen, Junfei Tong, Pengfei Dong, David L. Wilson, Hiram G. Bezerra, and Linxia Gu. "Mechanical Performance of PLLA Stent." In 2018 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dmd2018-6957.

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Stent implantation is widely used to treat blocked lumen. Stents were meshed structure made of polymers and metal alloys, including stainless steel, cobalt chrome and nitinol [1]. Clinical studies had demonstrated that stents helped to scaffold the diseased lesion up to one year when tissue adapted to the stented environment [2]. However, the permanently implanted stents inside artery were associated with complications such as stent fracture, tissue inflammation, in-stent restenosis and thrombosis [3]. Currently, biodegradable stents are attracting more attention due to its potential long-term
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Ghosh, Anirban, Jung-Hee Seo, and Rajat Mittal. "Coupled Fluid-Chemical Computational Modeling of Anticoagulation Therapies in a Stented Artery." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-52638.

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Stent thrombosis is a major complication that occurs after the placement of stents in the coronary artery through balloon angioplasty. The common treatment for stent thrombosis is to provide patients with anticoagulant and antiplatelet therapy through the bloodstream. This study uses numerical modeling to compare two delivery methods of heparin anticoagulant to the arterial wall to reduce thrombus formation: through the flow and via a drug-eluting stent. A unique computational fluid dynamics model is developed that couples an incompressible flow solver with a convection-diffusion-reaction equa
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Debusschere, Nic, Matthieu De Beule, Patrick Segers, Benedict Verhegghe, and Peter Dubruel. "Modeling of Coated Biodegradable Stents." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80425.

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A bioresorbable stent supports the stenosed blood vessel during the healing period after coronary angioplasty and then gradually disappears. Unlike permanent stents, the biodegradable stent forms no obstacle for future interventions. Moreover, the degradable stent material presents an ideal vehicle for local drug delivery. Long term side effects inherent to drug eluting stents such as in-stent restenosis and late stent thrombosis might be avoided [1]. To date, several bioresorbable stents are being developed or are currently being tested in clinical trials. Two classes of biomaterials are bein
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Karri, Satyaprakash, Stephen Peter, and Pavlos P. Vlachos. "Effect of Stent Design Parameters on Coronary Artery Flow." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206569.

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The most widely accepted modality for treating diseased arteries is the implantation of endovascular stents. Stents are metallic wireframe devices used to reopen clogged arteries. Despite their widespread use, problems persist post-implantation of these devices beginning with sub-acute thrombus formation followed by inflammation, proliferation and remodeling [1]. The specific stent design and its design parameters profoundly impact the hemodynamic environment of the stent [2], in turn affecting thrombus accumulation between struts and thus restenosis [3]. Prior research examining the hemodynam
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Berry, Joel L., and Saami K. Yazdani. "Stent Induced Smooth Muscle Cell Proliferation: An In Vitro System for Rapid Evaluation." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176798.

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The clinical efficacy of vascular stents is evaluated through long and expensive trials. Pre-clinical studies, where stents are tested in animal models, further contribute to the expense of bringing new devices to market. The purpose of pre-clinical studies is to assess stent induced thrombus formation, inflammatory response, neointimal hyperplasia, and late thromobosis. Whether the trial is pre-clinical or clinical, the biologic responses to stents are, in large part, due to the surface and structural characteristics of the stent being tested.
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Timmins, Lucas H., Clark A. Meyer, Michael R. Moreno, and James E. Moore. "Stented Artery Biomechanics in the Presence of Stenoses and Tapering." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176143.

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The implantation of a balloon expandable stent induces chronic stent-induced stresses on the artery wall. These highly non-physiologic stresses can provoke inflammation and smooth muscle cell proliferation. Ultimately, this cascade of events leads to restenosis, or the development of a new blockage in the stented artery. Since the initial human implantation of balloon expandable stents, technological advances in stent design, material properties, and deliverability have expanded the application and success rate of the procedure. More recently, anti-restenotic strategies such as drug-eluting st
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Fu, Gen, and Alexandrina Untaroiu. "A Computational Modelling for Hemodynamic Conditions Following Flow-Diverting Treatment in Cerebral Aneurysms." In ASME 2018 5th Joint US-European Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/fedsm2018-83408.

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Cerebral aneurysms are abnormal dilations of blood vessels within the skull that, in some cases, may rupture and bleed. The rupture of an aneurysm can cause significant bleeding into or around the brain (a stroke). Flow diverters are specially designed low porosity stents that are deployed into the parent artery to cover the neck of the aneurysm. The dense mesh-like structure of flow diverters aims at redirecting flow from the aneurysm to the parent artery and vice versa, resulting in flow stasis in the aneurysm and promoting thrombus formation conditions. The thrombosed aneurysm is then resor
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Bozsak, Franz, Jean-Marc Chomaz, and Abdul I. Barakat. "Dynamics of Arterial Wall Transport for Small Hydrophobic Drugs." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80541.

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Drugs used in drug-eluting stents (DES) to inhibit proliferation of smooth muscle cells (SMCs) also limit re-endothelialization at the site of stent implantation [1]. Thus, treated patients face an increased risk of late-stent thrombosis. Avoiding this adverse side effect represents one of the major challenges in the design of next-generation DES.
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Debusschere, Nic, Matthieu De Beule, Peter Dubruel, Patrick Segers, and Benedict Verhegghe. "Finite Element Modeling of Biodegradable Stents." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14493.

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Biodegradable stents, which temporarily support a stenotic blood vessel and afterwards fully disappear, have recently gained a lot of interest. They avoid long-term complications associated with conventional stents such as late stent thrombosis and in-stent restenosis. Moreover, degradable stents allow for a restoration of vasomotion and vessel growth which makes them particularly suitable for pediatric applications [1]. Finite element simulations have proven to be an efficient and cost-effective tool to investigate and optimize the mechanical performance of minimal invasive devices such as st
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