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Journal articles on the topic 'Thyroid colloid goiter'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Lima, Marcus A., Fabiana S. Tiveron, Vitorino M. Santos, Lilian M. B. Lima, Gilberto P. Silva, and Maria F. Borges. "C-cells in colloid goiter." Revista do Hospital das Clínicas 58, no. 6 (2003): 310–14. http://dx.doi.org/10.1590/s0041-87812003000600004.

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PURPOSE: The aim of this investigation was to quantitatively evaluate C-cells in colloid goiters, analyzing 36 thyroids that were obtained through thyroidectomy from 24 patients with goiter and 12 normal glands from adult patients without thyroid disease, which were used as the control group. MATERIAL AND METHODS: On average, 6 different thyroid areas were sampled and labeled by immunohistochemistry with a monoclonal anticalcitonin antibody, utilizing the avidin-biotin-peroxidase complex. C-cells were counted in fields measuring 1 square centimeter, and the mean number of cells per field was t

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NIAZI, S., M. ARSHAD, and M. MUNEER. "A Histopathological Audit of Thyroid Surgical Specimens." Annals of King Edward Medical University 13, no. 1 (2021): 51–56. https://doi.org/10.21649/akemu.v13i1.4659.

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Objective: This study was conducted to see the frequency of different morphological lesions encountered in surgically excised thyroid glands. Study design: Descriptive cross sectional study. Place and duration of study: The study was conducted at the Department of Pathology, King Edward Medical University, Lahore during a 2-year period commencing from 1st January 2005 to 31st December 2006. Materials & methods: All thyroid surgical specimens referred from the four major Surgical Units of Mayo Hospital, Lahore, to the Department of Pathology, King Edward Medical University, Lahore, during a

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Stuchi, Leonardo P., Márcia Maria U. Castanhole-Nunes, Nathália Maniezzo-Stuchi, et al. "VEGFA and NFE2L2 Gene Expression and Regulation by MicroRNAs in Thyroid Papillary Cancer and Colloid Goiter." Genes 11, no. 9 (2020): 954. http://dx.doi.org/10.3390/genes11090954.

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Deregulation of VEGFA (Vascular Endothelial Growth Factor A) and NFE2L2 (Nuclear Factor (Erythroid-derived 2)-Like 2), involved in angiogenesis and oxidative stress, can lead to thyroid cancer progression. MiR-17-5p and miR-612 are possible regulators of these genes and may promote thyroid disorders. In order to evaluate the involvement of VEGFA, NFE2L2, hsa-miR-17-5p, and hsa-miR-612 in thyroid pathology, we examined tissue samples from colloid goiter, papillary thyroid cancer (PTC), and a normal thyroid. We found higher levels of VEGFA and NFE2L2 transcripts and the VEGFA protein in goiter a

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Rogova, O. S., L. N. Samsonovа, and G. F. Okminyan. "STRUCTURE OF THE NODULAR GOITER IN CHILDREN." Bulletin of Siberian Medicine 14, no. 5 (2015): 54–60. http://dx.doi.org/10.20538/1682-0363-2015-5-54-60.

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For today the question of early diagnosis of nosological variants, the method of treatment and prevention of nodular goiter in children is still not fully resolved. There is a few available literature data about study of this problem in children. Objective: to study morphofunctional structure of thyroid nodules in children.The article provides information consisting of the results of a retrospective analysis of case histories of 73 patients, operated with nodular goiter in Z.A. Bashlyaeva Children’sCityClinicalHospital(Moscow) from 2003 to May 2015. The examination included an evaluation of th

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Mayya, Jaya Prakasha, Nabin Gautam, Apar Pokharel, and Bikash Pandey. "Case report: An interesting case of large colloid goiter with dyspnea." Journal of College of Medical Sciences-Nepal 13, no. 4 (2017): 430–32. http://dx.doi.org/10.3126/jcmsn.v13i4.18680.

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Benign nodular goitre is one of the most common endocrine disorder, especially in countries like Nepal where iodine deficiency is endemic. Case History: A 59 years old female presented with large thyroid swelling. Investigations showed it to be colloid goiter compressing the airway. Left hemithyroidectomy was done. Post operative period was uneventful.Discussion: Management of thyroid nodules depends upon assessment of thyroid function, fine needle aspiration cytology and imaging. Surgery is the common method of treatment.

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Troshina, E. A., N. P. Makolina, E. A. Kolpakova, et al. "Structural and morphologic characteristics of nodular goiter in chronic iodine deficiency status." Clinical and experimental thyroidology 19, no. 1 (2023): 20–28. http://dx.doi.org/10.14341/ket12748.

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OBJECTIVES. Diffuse and nodular goiter are the most common thyroid gland (thyroid) diseases in children and adults living in iodine-deficient regions. Thyroid hormone potentiates progressive hypertrophy and hyperplasia of thyrocytes, with uneven proliferation of thyroid cells leading to nodule formation. Iodine deficiency, which promotes replication of thyroid follicular cells, also increases the incidence of TSH Receptor mutations, leading to receptor activation and autonomous functioning of follicles.AIM. To evaluate and describe ultrasound and cytologic thyroid nodes in the regions in Russi

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Syed Abdul Hakeem. "Analysis of Thyroid Cases in a Teaching Hospital." Academia Journal of Surgery 3, no. 1 (2020): 155–58. http://dx.doi.org/10.47008/ajs/2020.3.1.33.

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Background: Hyperthyroidism, hypothyroidism, inflammation of thyroid (thyroiditis), thyroid enlargement (goitre), thyroid nodules and thyroid cancer are amongst the thyroid disorders. The study aims to the occurrence of various post-operative complications following thyroidectomy. Subjects and Methods: One hundred patients who underwent thyroid surgery, for various thyroid disorders were taken for the study. elaborate analysis of those patients who underwent thyroidectomy was done relating to numerous aspects like age, sex, diagnosis & indication for surgery, type of thyroidectomy procedur

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8

N. P. Tkachuk and I. S. Davydenko. "Certain peculiarities of parenchymal-stromal correlations in the thyroid gland with nodular forms of goiter with its rucurrent and non-recurrent course." Clinical anatomy and operative surgery 19, no. 1 (2020): 53–60. http://dx.doi.org/10.24061/1727-0847.19.1.2020.9.

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In spite of a considerable efficacy of conservative treatment of goiter, surgery remains the main method of treatment of such patients. Though, on the one hand, total thyroidectomy inevitably results in the development of postsurgical hypothyroidism, on the other hand – in case organ-saving surgery is performed the risk of postsurgical relapse arises. Modern morphological methods are directed to detection of oncological risk of nodular formations, and recommendations concerning an adequate volume of surgery taking into account probability of relapse are practically lacking. Therefore, the obje

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Yadav, Abhilasha, Manjula Jain, Charu Agarwal, Mukta Pujani, Dipti Sidam, and Ruchira Wadhwa. "Isolated Tuberculosis of the Thyroid Gland: A Common Disease at an Uncommon Location." International Journal of Advanced Medical and Health Research 10, no. 2 (2023): 112–14. http://dx.doi.org/10.4103/ijamr.ijamr_163_23.

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Abstract Tuberculosis (TB) of the thyroid gland is extremely rare, even in areas where the prevalence of TB is very high. Only a few such cases have been reported in the literature. The clinical course may resemble toxic goiter or acute thyroiditis. We report the case of a 23-year-old male who presented with painless swelling of the thyroid gland associated with mild fever and weight loss. On ultrasound neck, a large echogenic solid lesion was seen. Fine-needle aspiration cytology was suggestive of colloid goiter, but histopathology study suggested TB of the thyroid gland along with colloid go

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Shalini Kashyap and Anil Kumar Gupta. "Cytomorphological Assessment of FNAC Findings of Thyroid Swellings." Asian Journal of Medical Research 9, no. 1 (2020): PT16—PT19. http://dx.doi.org/10.47009/ajmr.2020.9.1.pt5.

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Background: There is enormous burden of thyroid diseases in the general population. Among all the endocrine disorders, thyroid disorders are the most common in India. The present study was conducted to assess FNAC findings of thyroid swellings. Subjects and Methods: The present study was conducted on 108 patients with thyroid swellings. A thorough clinical examination was performed. USG findings were recorded in the available patients. FNAC was done as per standard protocols. Results: Out of 108 cases, males were 32 and females were 76. Common thyroid swelling was colloid nodular/adenomatous g

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11

Makarov, A. D., Yu M. Keda, I. V. Kryukova, et al. "The hypothalamo-hypophyseal system in patients with multinodular colloid euthyroid goiter." Problems of Endocrinology 40, no. 3 (1994): 22–25. http://dx.doi.org/10.14341/probl12006.

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Eighty patients with multinodular colloidal euthyroid goiter were examined. Thyrotropin-releasing hormone (TRH) test was carried out in 22 patients and 7 healthy women. The results of the test indicate a clear-cut tendency to reduction of hypophyseal TTH reserve in patients with multinodular euthyroid goiter with enlarged thyroid. In other words, clinical diagnosis of an euthyroid condition in the examinees appears to be groundless, particularly in patients with stage IV multinodular euthyroid goiter who may be referred to latent hyperthyrosis group on the basis of TRH test results. Three type

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Karachentsev, Yu I., V. M. Dubovik, I. V. Gopkalova, et al. "Frequency of combinations of different histological forms of papillary thyroid cancer with other diseases of the thyroid parenchyma." Problems of Endocrine Pathology 67, no. 1 (2019): 23–29. http://dx.doi.org/10.21856/j-pep.2019.1.03.

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The authors showed that in the prevailing majority of cases (71 %) papillary carcinomas were formed against the background of other thyroid diseases. In this work, the main forms of thyroid pathology, which is most often found in PTC, were identified and their frequency was determined. It has been proven that in 39.8 % of cases PTC was combined with only one of the following diseases: in 20 % with autoimmune thyroiditis, in 14.8 % with colloid goiter, in 5 % with follicular adenomas. The combination of PTC with not one, but with several thyroid pathologies is 31.4 %. Such a high frequency of c

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Ravindran, R., Varun Bassessar, Priyanka Syal, and Sunil Punia. "Familial Congenital Hyperplastic and Colloidal Goitre in a Beetle Goat." International Journal of Bio-resource and Stress Management 15, Nov, 11 (2024): 01–06. https://doi.org/10.23910/1.2024.5631.

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An investigation was conducted at the Veterinary Clinical Complex, College of Veterinary Science, COVS, GADVASU Rampura Phul, Punjab, India during May, 2023 to study the pathomorphological alterations of Hyperplastic and Colloidal Goiter in a beetal. Two new born kids were considered that included one dead and other with history of no suckling, lassitude, not able to rise its head and swelling in cranioventral neck region. Post mortem examination of dead kid showed markedly swollen thyroid gland and samples collected from them were subjected to routine H&E examination. Histopathological ex

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Tyagi, Mohini, and Probal Chatterjee. "A clinico-pathological study of patients with thyroid swelling and their management in a tertiary care centre in western Uttar Pradesh." Asian Journal of Medical Sciences 12, no. 1 (2021): 95–99. http://dx.doi.org/10.3126/ajms.v12i2.31078.

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Background: Thyroid diseases are common worldwide and in India too there is a significant burden of thyroid disease. Thyroid disease has a reported prevalence of 4-7% in the general population on neck palpation and in autopsy series it may be as high as 50% if subclinical nodules are included. The clinical presentation of thyroid swellings can be very misleading and a definitive diagnosis cannot be done without proper investigations. Aims: To conduct a clinic-pathological study of thyroid swellings along with their management in a tertiary care center. Objectives: 1. To study the v

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Budhiraja, Grace, Harsimrat Singh Dhingra, Danish Guram, Sumati Goyal, and Pulkit Bharti. "An unusual presentation of large colloid goiter – A case report." Adesh University Journal of Medical Sciences & Research 2 (July 23, 2020): 64–66. http://dx.doi.org/10.25259/aujmsr_14_2020.

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Benign nodular goiter is a frequently encountered endocrine disorder during routine clinical practice, especially in countries like India where iodine deficiency is endemic. Here, we present the case history of a 55-year- old male who presented with a large thyroid swelling. Investigations revealed it to be colloid goiter. The right hemithyroidectomy under general anesthesia was done. Post-operative period was uneventful. Hence, in this article, we discuss management of thyroid nodules which depend on assessment of thyroid function, fine-needle aspiration cytology, and imaging. For such nodule

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Vnotchenko, S. L., T. A. Okeanova, M. E. Bronshtein, S. B. Nefedov, and G. I. Fedoseeva. "Fine needle puncture biopsy and imaging methods of the thyroid gland in the diagnosis of nodular goiter." Problems of Endocrinology 39, no. 6 (1993): 30–33. http://dx.doi.org/10.14341/probl11936.

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A retrospective analysis of the results of puncture thyroid biopsy is presented in 256 patients operated on for nodular goiter. Cytological data coincided with histological in 84.8% of cases. Coincidences were most frequent with (multiple) nodular colloid goiter and thyroid cysts (95.7 = 100%) and the least with a single adenoma (65.4%) of predominantly follicular structure. In thyroid cancer, the data correlated in 75% of cases. The presence of cystic changes in the adenoma made the study less informative. The results of an ultrasound examination of the thyroid gland coincided with operationa

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Camargo, Rosalinda Yasato, Cristina Takami Kanamura, Celso Ubirajara Friguglietti, et al. "Histopathological Characterization and Whole Exome Sequencing of Ectopic Thyroid: Fetal Architecture in a Functional Ectopic Gland from Adult Patient." International Journal of Endocrinology 2018 (2018): 1–10. http://dx.doi.org/10.1155/2018/4682876.

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Ectopic thyroid results from a migration defect of the developing gland during embryogenesis causing congenital hypothyroidism. But it has also been detected in asymptomatic individuals. This study aimed to investigate the histopathological, functional, and genetic features of human ectopic thyroids. Six samples were histologically examined, and the expression of the specific thyroid proteins was assessed by immunohistochemistry. Two samples were submitted to whole exome sequencing. An oropharynx sample showed immature fetal architecture tissue with clusters or cords of oval thyrocytes and sma

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18

Schiller, C. A., R. J. Montali, S. Doi, and E. F. Grollman. "Clinical and Morphologic Findings of Familial Goiter in Bongo Antelope (Tragelaphus eurycerus)." Veterinary Pathology 32, no. 3 (1995): 242–49. http://dx.doi.org/10.1177/030098589503200305.

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Inherited defects of thyroglobulin synthesis resulting in congenital goiter are well described in certain breeds of domestic ungulates and in human beings. Goiter associated with synthesis of an abnormal thyroglobulin and the presence of thyroidal albumin was identified in five closely related bongo antelopes ( Tragelaphus eurycerus). The goiter had an adult onset, and the affected bongos appeared to remain euthyroid with normal serum T3 and T4 values, normal serum cholesterol concentrations, and nonelevated concentrations of circulating thyroid stimulating hormone (TSH). Goitrous bongos had s

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19

Troshina, E. A., A. A. Alexandrov, G. A. Gerasimov, et al. "L-thyroxine in the treatment of solitary nodular non-toxic goiter in concomitant coronary heart disease." Problems of Endocrinology 45, no. 3 (1999): 25–28. http://dx.doi.org/10.14341/probl11765.

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Endocrinological and cardiological parameters were assessed in coronary patients with nodular euthyroid goiter before and during treatment in order to define the optimal protocols of L-thyroxin therapy. Ultrasonic examination of the thyroid, fine needle puncture biopsy and cytological analysis of biopsy specimens, measurements of thyrotropic hormone, electrocardiography, and high resolution electrocardiography were carried out. The results helped distinguish the cardiological criteria for decreasing the dose of L-thyroxin or its discontinuation in coronary patients with nodular goiter and defi

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Mudduwa, Lakmini, Thusharie Liyanage, Yamuna Mudduwa, Deepthika Abeysiriwardhana, and Ajith Liyanage. "Post-iodination trends in thyroid pathology; 14-year experience at a single center in a goitre endemic area." Galle Medical Journal 28, no. 1 (2023): 21–29. http://dx.doi.org/10.4038/gmj.v28i1.8190.

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Introduction: Goitre is endemic in many parts of Sri Lanka. Universal iodination of salt was commenced in Sri Lanka in 1995 as a measure to reduce the prevalence. This study was designed to identify the pattern of thyroid pathology reported during a period of 14 years from 2002 to 2015 in a Pathology Unit serving the population in a goitre endemic area in Sri Lanka.Methods: This descriptive cross-sectional study included all thyroidectomy specimens histologically assessed at our unit from 2002 to 2015. Data on age, gender, clinical presentation, type of resection, and histopathological diagnos

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Mahadani, Jayawant, and Huzefa Ali Turkey. "Analysis of histopathological pattern of thyroid lesions in a tertiary care hospital." IP Archives of Cytology and Histopathology Research 7, no. 1 (2022): 42–46. http://dx.doi.org/10.18231/j.achr.2022.008.

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Thyroid gland is unique in having a wide spectrum of disorders and these thyroid disorders are common worldwide. However, the thyroid gland lesions vary in their incidence and histopathological patterns. Hence the present study was undertaken to determine thehistopathological pattern of thyroid lesions in Tertiary Care Centre. Total 80 thyroidectomy specimens received in the Pathology Department during a period from January 2018 to December 2019 were included in the study. Detailed information regarding age, gender, clinical status, relevant investigations like fine needle aspiration cytology,

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Semenov, D. Iu, L. E. Koloskova, M. E. Boriskova, et al. "Galectin-3 expression in preoperative diagnosis of highly differentiated thyroid cancer." Problems of Endocrinology 56, no. 4 (2010): 9–15. http://dx.doi.org/10.14341/probl20105649-15.

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Galectin-3 expression in fine-needle aspiration biopsies from 66 patients with thyroid Nodes (TN) was studied by flow fluorocytometry (FFC). Cytological study revealed 29 patients with papillary thyroid cancer, 31 with follicular tumour, and 6 with colloid nodular goiter. Galectin-3 expression was documented in 27 of the 29 patients with preoperative diagnosis of papillary cancer; in 25 (92.6%) of these cases diagnosis of highly differentiated cancer was confirmed histologically, the remaining 2 (7.4%) cases presented with benign thyroid disease. Two (6.9%) patients without galectin-3 expressi

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Tuna, Trinny, Nur Hijra Puji Astuti, Sri Andriani Ibrahim, Abdi Dzul Ikram Hasanuddin, and Romy Abdul. "Characteristics of Thyroid Neoplasm Patients in the Department of Anatomic Pathology, Aloei Saboe Hospital." Jambura Medical and Health Science Journal 2, no. 1 (2023): 20–27. http://dx.doi.org/10.37905/jmhsj.v2i1.18835.

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Introduction: Thyroid Neoplasm is a tumor originating from the thyroid gland. Thyroid neoplasms encompass both benign and malignant tumors. Thyroid malignancies are among the most frequently encountered malignancies of the endocrine glands. Thyroid neoplasms generally have a relatively good prognosis when detected early. This study aims to determine the characteristics of thyroid neoplasm patients in the Department of Anatomic Pathology, Aloei Saboe Hospital.Method: This study is descriptive research using secondary data from medical records. Data was collected using a total sampling technique

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Lucas, Anna, Mariona Llatjós, Isabel Salinas, Jordi Reverter, Eduarda Pizarro, and Anna Sanmarti. "Fine-needle aspiration cytology of benign nodular thyroid disease. Value of re-aspiration." European Journal of Endocrinology 132, no. 6 (1995): 677–80. http://dx.doi.org/10.1530/eje.0.1320677.

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Lucas A, Llatjós M, Salinas I, Reverter J, Pizarro E, Sanmarti A. Fine-needle aspiration cytology of benign nodular thyroid disease. Value of re-aspiration. Eur J Endocrinol 1995;132:677–80. ISSN 0804–4643 Fine-needle aspiration cytology (FNAC) has become a widespread procedure for the study of thyroid nodules (TN). Some authors recommend the practice of repeated punctures for their follow-up. This study was done to determine the usefulness of repeated FNAC in patients with benign nodular thyroid disease. We have studied 251 fine-needle re-aspirations performed on 116 females aged 45.6 ± 14 ye

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Aleksandrov, Yu K., Vasiliy I. Semikov, V. A. Kudachkov, and E. I. Sokolova. "The remote results of laser destruction of proliferating colloidal goiter." Medical Journal of the Russian Federation 22, no. 1 (2016): 7–9. http://dx.doi.org/10.18821/0869-2106-2016-22-1-7-9.

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The article presents the remote results (time-period more than 1 year) of application of percutaneous laser destruction in treatment of nodular goiter in 164 patients. The reliable decreasing of dimensions and size of nodular formations of thyroid gland in early time-periods with continuation of regression during a year is established. In the following, slight regression was marked during 3,5-5 years. The morphological analysis established that in remote time-periods after percutaneous laser destruction of nodular proliferating colloid goiter the destroyed follicular epithelium and colloid are

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Bikram, Chandra Lenka, and Bhaskar Basrur Gurudutt. "Study of Clinical Manifestations and Management of Thyroid Swelling." International Journal of Pharmaceutical and Clinical Research 14, no. 12 (2022): 117–20. https://doi.org/10.5281/zenodo.13208092.

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<strong>Introduction:</strong>  In India about 170 million people suffer from thyroid disease. The world’s largest goiter belt is the Himalayan goiter belt from Kashmir in the north to Naga Hills in the east. Thyroid disease is a condition that affects the functioning of the thyroid gland. <strong>Methodology:</strong> The present study was carried out in Department of Surgery, for last one year. We randomly selected patients with thyroid swelling. We collected data from 50 patients for this study. The patients history, clinical presentation, investigations and followed up

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Priya, Sunda, Mali Neha, Prakash Vyas Surendra, Kumar Yogesh, and Dawan Sharda. "Study of Spectrum of Various Histopathological Patterns in Specimens of Thyroid Surgeries: A Combined Prospective and Retrospective Study Design." International Journal of Toxicological and Pharmacological Research 13, no. 5 (2023): 245–54. https://doi.org/10.5281/zenodo.11214234.

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<strong>Introduction:</strong> Among all the endocrine disorders, thyroid gland disorders are commonest in India. Thyroid lesions may be developmental, inflammatory, hyperplastic and neoplastic. To establish final diagnosis, histopathological evaluation is vital. Therefore the present study was conducted with the objective to analyse the histological spectrum of thyroid diseases, frequency of malignant lesions and their correlation with age and sex. <strong>Material and Methods:</strong> This study was a hospital based, both prospective and retrospective type of study. It w

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Dolidze, D. D., S. D. Kovantsev, Z. A. Bagatelia, et al. "Ultrasound-guided core-needle biopsy for diagnosis of thyroid cancer." Pirogov Russian Journal of Surgery, no. 3 (March 19, 2025): 87. https://doi.org/10.17116/hirurgia202503187.

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Objective. To improve preoperative examination of patients with follicular thyroid tumors using ultrasound-guided core-needle biopsy. Material and methods. All patients with Bethesda IV (follicular tumor) underwent ultrasound-guided core-needle biopsy of thyroid neoplasm according to original technique (patent No. 2826474 RU). Preoperative histological specimen after core needle biopsy was compared with urgent and elective histological examination. Statistical analysis was carried out using Kolmogorov-Smirnov and Kruskal—Wallis tests. Differences were significant at p<0.05. Results. Thyroid

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Thakkar, Dhaval B., Satish D. Deshmukh, and Murtaza Akhtar. "Nontoxic goiter: causes, clinical evaluation and management." International Surgery Journal 5, no. 5 (2018): 1873. http://dx.doi.org/10.18203/2349-2902.isj20181600.

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Background: Thyroid diseases are the commonest endocrine disorders worldwide and India is no exception. Goiter may be generalized or localized, toxic or nontoxic. The present study is being carried out in a government notified endemic area to study the etiology and surgical management with postoperative complications in patients with nontoxic goiter.Methods: A observational study was carried out at a tertiary care academic hospital. Patients with a clinically diagnosed nontoxic goiter with normal T3, T4 and TSH values were included in the study. The study subjects underwent relevant investigat

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Sharma, Bibek, Alina Baral, Apar Pokharel, and Deepak Jung Subedi. "Comparative Study of FNAC and Histopathology in Diagnosis of Thyroid Swelling." Journal of College of Medical Sciences-Nepal 19, no. 3 (2023): 345–49. http://dx.doi.org/10.3126/jcmsn.v19i3.54039.

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IntroductionFine Needle Aspiration Cytology (FNAC) is important for pre-operative and pre-treatment diagnosis of benign and malignant thyroid lesions, thus decreasing the incidence of unwanted surgeries. The objective of this research is to compare the FNAC and Histopathological findings of thyroid swelling.MethodsThe present study is a cross sectional study conducted on 30 patients in the Department of Otorhinolaryngology Head and Neck Surgery, College of Medical Sciences, Bharatpur, Nepal from January 2022 to December 2022. Thyroid swelling presented to OPD were examined clinically after tho

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Vetshev, P. S., K. E. Chilingaridi, L. I. Ippolitov, et al. "The first experience of laser spectroscopy in the surgical treatment of thyroid diseases." Problems of Endocrinology 45, no. 1 (2019): 17–20. http://dx.doi.org/10.14341/probl11694.

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For assessing the efficacy of intraoperative laser autofluorescent spectroscopy (IOLAS), 46 patients with thyroid diseases of different etiology are examined. The patients ’ aged varied from 30 to 65 years. The following morphological types of diseases were observed: benign nodular formations in 42 patients, thyroid cancer in 4, papillary TINO MO in 2, and follicular cancer TINO MO in 2 cases. Out of benign formations, 36 were multinodular colloid goiter and 6 follicle-cell adenomas. As a result of using IOLAS, thyroid cancer was diagnosed during surgery in 8 (17.4%) out of 36 patients with mu

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Das, Manish Kumar, and Meenakshi Basnet. "Cytological Evaluation of Thyroid and its Correlation with Thyroid Function Test and Anti-Thyroid Peroxidase in a Patient of Hashimoto’s Thyroiditis." Journal of Nobel Medical College 8, no. 2 (2019): 57–61. http://dx.doi.org/10.3126/jonmc.v8i2.26791.

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Background: A thyroid swelling is an enlargement of thyroid glands causes by iodine deficiency, ageing, autoimmune disease and benign or malignant tumors. Autoimmune thyroiditis is the second most common thyroid lesion diagnosed after goiter. Materials and Methods: To find out the distribution of thyroid gland swelling in patients visiting otorhinolaryngology department of Nobel medical college and correlate serum thyroid function test and anti-thyroid peroxidase level with fine needle aspiration cytology reports. Results: The mean age of patient with thyroid gland lesions was 40.4

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Petrova, Tatiana Nikolaevna, Olga Nikolaevna Krasnorutsky, and Daniel Yuryevich Bugrimov. "Morphofunctional state estimation of the thyroid remainder after thyroid gland resection." Journal of Experimental and Clinical Surgery 4, no. 1 (2011): 118–21. http://dx.doi.org/10.18499/2070-478x-2011-4-1-118-121.

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The morphofunctional dynamics of the thyroid remainder after the thyroid gland resection on occasion the colloid goiter are considered and analysed. The technique of the patients rehabilitation in early postoperation term including the complexes therapy of multivitaminous complex Vitrum with combination of correction the hormonal status is proposed. The application of rehabilitation scheme in comparison with traditional observation after operating term permits to prevent the development of postoperation complication to reduce the term of temporal invalidity and to improve the quality life of t

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Patel, Seema, Varsha J. Gattani, and Ashok Z. Nitnaware. "Clinicopathological study of thyroid swelling and its management." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 4 (2020): 727. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20201290.

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<p class="abstract"><strong>Background:</strong> There is high prevalence of thyroid lesions in India. In this study, an attempt is made to find out the clinical spectrum of thyroid swellings in central India, diagnostic accuracy of fine needle aspiration cytology (FNAC), appropriate surgical management and to compare it with postoperative histopathological diagnosis so as to determine its role in surgical management.</p><p class="abstract"><strong>Methods:</strong> In this prospective study, 100 subjects presenting to ENT OPD of GMC, Nagpur during the

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Nikitski, Alyaksandr, Vladimir Saenko, Mika Shimamura, et al. "Targeted Foxe1 Overexpression in Mouse Thyroid Causes the Development of Multinodular Goiter But Does Not Promote Carcinogenesis." Endocrinology 157, no. 5 (2016): 2182–95. http://dx.doi.org/10.1210/en.2015-2066.

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Abstract Recent genome-wide association studies have identified several single nucleotide polymorphisms in the forkhead box E1 gene (FOXE1) locus, which are strongly associated with the risk for thyroid cancer. In addition, our recent work has demonstrated FOXE1 overexpression in papillary thyroid carcinomas. To assess possible contribution of Foxe1 to thyroid carcinogenesis, transgenic mice overexpressing Foxe1 in their thyroids under thyroglobulin promoter (Tg-Foxe1) were generated. Additionally, Tg-Foxe1 mice were exposed to x-rays at the age of 5 weeks or crossed with Pten+/− mice to exami

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Khaziev, V. V. "FEATURES OF CELLULAR COMPOSITION OF LYMPHO-MACROPHAGE INFILTRATION IN THE STROMA OF BENIGN AND MALIGNANT NODAL THYROID NEOPLASMS." Problems of Endocrine Pathology 45, no. 3 (2013): 14–21. http://dx.doi.org/10.21856/j-pep.2013.3.02.

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It was conducted immunohistochemical definition of the relative amounts of CD8 (T-lymphocytessuppressor), CD4 (T-lymphocyte helper/inducer), CD3 (total population of T-lymphocytes), CD22(B-lymphocytes), CD16 (macrophages and natural killer) and interleukin-2-producing cells (IL-2) inthe preparations of euthyroid nodular thyroid disease: single and multinodal colloid goiter, thyroidfollicular adenomas (norm-follicular, macrofollicular, microfollicular, trabecular and solid), thyroidcancer (follicular, papillary, medullary). The nodular goiter characterized by a low level of T-killer,IL-2 and CD

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Halbhavi, Subhash N., Mahantayya Ganjigatti, Shrikant B. Kuntoji, and Mohammedgouse A. Karikazi. "Clinicopathological study of thyroid swellings in HSK hospital in Karnataka, India." International Surgery Journal 5, no. 2 (2018): 420. http://dx.doi.org/10.18203/2349-2902.isj20180038.

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Background: A thyroid enlargement whether diffuses or in the form of nodules have to be investigated to rule out neoplasm. FNAC is the first line of investigation. USG and TFT are also used. The cases which are at high risk are considered for surgery. Aims and objectives of the study was the clinical presentation of thyroid swellings, incidence of various thyroid swelling, benign versus malignant lesion and to correlate the clinical diagnosis with that of pathological diagnosis.Methods: A case series study of 60 patients attending surgical OPD IPD with symptoms of thyroid in SNMRC and HSK hosp

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Mishra, Shree, Sushree Kar, and Debasis Behera. "Clinico-cytomorphological features and thyroid function tests of different thyroid lesions – A hospital-based cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 13, no. 9 (2023): 1. http://dx.doi.org/10.5455/njppp.2023.13.01037202325012023.

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Background: Thyroid gland is an endocrine organ. The non-neoplastic and neoplastic conditions affecting the gland can manifest as the swelling of the gland with thyroid dysfunction. Based on cytology, the diseases can be categorized into non-neoplastic, benign neoplastic, and malignant neoplastic conditions and according to hormone status, the lesions of thyroid can be categorized in hypothyroid, euthyroid, or hyperthyroid condition. Aims and Objectives: Our study was done to find out the various cytomorphological spectrum of thyroid diseases and to record their common clinical presentation al

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Timofeeva, L. A. "Diagnostic tactics for thyroid nodules." Kazan medical journal 93, no. 1 (2012): 103–7. http://dx.doi.org/10.17816/kmj2157.

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Aim. To determine the optimal diagnostic tactics for nodules of the thyroid gland. Methods. Examined were 1124 patients with thyroid nodules in the age from 14 to 60 years and older, of whom 159 - with malignant tumors, 180 - with adenomas, 620 - with colloid nodes, 165 - with cysts. Among the surveyed group were 844 women and 280 men. The group of healthy individuals included 400 people. The material for cytology was obtained by fine-needle aspiration biopsy (1004 studies), from smears from the cut surface of the tumor (76 studies) and from puncture biopsies of enlarged regional lymph nodes (

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Mujeeb, Madeeha, Jasmeen Tabassum, Naushaba Tazeen, Idrees Afroze, and Imtiyaz Khan. "Cartilaginous metaplasia of thyroid nodule." Journal of Medical and Allied Sciences 15, no. 1 (2025): 92. https://doi.org/10.5455/jmas.214579.

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Adenomatous goiter is the most common form of thyroid disease. Although degenerative changes like fibrosis, calcification, cystic changes and hemorrhagic tissue are commonly found, cartilaginous metaplasia is an unusual phenomenon in the thyroid gland. Heterotopic cartilage formation is a very rare finding in both neoplastic and non-neoplastic lesions. Only 2 cases have been reported so far. Here we present a case of a 65-year-old female who presented with a midline swelling in her neck for 2 months associated with difficulty in swallowing. The lymph nodes were not palpable and there were no p

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Gupta, Mudit, Rajeev Kumar Mahaseth, Sajish Khadgi, Asmita Shrestha, Neeti Bhat, and Alina Karna. "Thyroid Swellings Undergoing Thyroidectomy in a Tertiary Hospital of Nepal: A Retrospective Study of Distribution and Prevalence of Malignancy." Nepal Journal of Health Sciences 1, no. 2 (2021): 27–33. http://dx.doi.org/10.3126/njhs.v1i2.42373.

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Introduction: Thyroid nodules brought to a hospital are checked for cancer. A post-operative histological examination is a gold standard for diagnosing thyroid lesions. Treatment is aided by a prior understanding of the disease’s underlying pattern. Objective: A retrospective study was done to determine the prevalence and distribution of malignancy in suspicious thyroid nodules. Methods: The study was conducted at Ganesh Man Singh Memorial Academy of ENT- Head and Neck studies from August 2017 to March 2020. All the subjects (n=183) presenting with a thyroid nodule and who had post-operative h

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Bhargava, Anuja, Syed M. Faiz, M. Shakeel, Nafas J. Singh, and Saloni Singh. "Clinicopathological study of asymptomatic thyroid swelling and its correlation with thyroid function tests." International Journal of Otorhinolaryngology and Head and Neck Surgery 5, no. 3 (2019): 727. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20191739.

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<p class="abstract"><strong>Background:</strong> Thyroid swelling without symptomatic manifestation is common occurrence and could affect 5 to 20% patients in endemic areas. Majority of them are non neoplastic and may not require surgery. Less than 5% of thyroid nodules are malignant.</p><p class="abstract"><strong>Methods:</strong> Present study was conducted to correlate clinical findings, HRUSG findings, thyroid profile and FNAC findings in patients of asymptomatic thyroid swelling. </p><p class="abstract"><strong>Results:</stro

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Ullah, Arif, Azam Khan, Muhammad Hussain Afridi, Syed Zafar Hasan, and Khaddija Bibi. "Techniques for Treating a Single Cold Thyroid Nodule." Pakistan Journal of Medical and Health Sciences 16, no. 8 (2022): 963–65. http://dx.doi.org/10.53350/pjmhs22168963.

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Background: The goal of this article is to raise awareness of malignancy and surgical options for the solitary inflection point of the cold nodule thyroid. Methods: People mentioned after the community or hospitalized straight via Observational Patient Treatment Tartary care hospital kpk with a diagnosis of a single cold nodule thyroid gland were accounted for in the study. Results: The patients' ages varied from 15 to 65, with a mean of 35 10 years, and 90% were female. Sixty-four percent of patients had problems in the right lobe of the thyroid gland, whereas only two percent had problems in

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Sich, Yu P., and E. P. Fisenko. "Comparative analysis of TI-RADS modifications." Medical Visualization, no. 5 (October 28, 2018): 14–20. http://dx.doi.org/10.24835/1607-0763-2018-5-14-20.

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There is no single classification of TI-RADS. In different countries, various modifications are used. It is necessary to compare different versions of the classification for choosing the most optimal variant.Objective: a comparative “blind” assessment of the thyroid nodules identified by ultrasound, according to the TI-RADS scale in various modifications.Materials and methods. Retrospective analysis of 153 echograms of thyroid lesions: colloid goiter/nodular colloid goiter – 77 observations, autoimmune thyroiditis – 11, follicular adenoma – 77, follicular cancer – 2, medullar cancer – 1, papil

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Makani, Akash D., Nitin Nangre, and Akshay Nerlekar. "Patient Demographics and Characteristics Associated with Solitary Thyroid Nodules." Azerbaijan Pharmaceutical and Pharmacotherapy J 22, no. 2 (2023): 63–65. http://dx.doi.org/10.61336/appj/22-2-17.

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Background: Fine Needle Aspiration Cytology (FNAC) has emerged as the primary approach for the initial assessment of thyroid nodules, followed by ultrasound scanning and a thyroid profile analysis. This study aims to analyze the prevalence of solitary thyroid nodules and investigate the factors contributing to malignancies in patients with solitary thyroid nodules. Methods: The study encompassed a total of 50 cases. In all instances, a neck ultrasound was performed to exclude multinodular goiter. Fine Needle Aspiration Cytology (FNAC) served as the primary diagnostic procedure for assessing th

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Styazhkina, S. N., A. I. Rysov, T. V. Fedulova, et al. "Atypical location of the thyroid node in the upper section of the neck (clinical observation)." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 13, no. 5 (2023): 121–24. http://dx.doi.org/10.20340/vmi-rvz.2023.5.case.1.

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Currently, there is an increase in the number of patients with nodular formations of the thyroid gland (TG), which requires preoperative diagnostics, which allows to detect in a timely manner follicular neoplasia and highly differentiated forms of cancer, colloid goiter with compression of the neck organs, nodular and diffuse toxic goiter (DUS) [5]. Most often, the nodes are located in the thyroid gland, but there are cases with atypical localization. Ectopia of the thyroid gland, or thyroid ectopia (from the Greek “ektopos”, i.e. “displaced”) is the presence of its atypical tissue in a place

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Jaffar, Reema, Sambit K. Mohanty, Ashraf Khan, and Andrew H. Fischer. "Hemosiderin laden macrophages and hemosiderin within follicular cells distinguish benign follicular lesions from follicular neoplasms." CytoJournal 6 (January 19, 2009): 3. http://dx.doi.org/10.4103/1742-6413.45193.

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Background: Published criteria to distinguish benign colloid nodules from follicular neoplasms emphasize only three interdependent features: size of follicles, amount of colloid, and cellularity. There is a need for the validation of other independent criteria. Methods: This study quantified the significance of cystic change, defined as presence of macrophages, and the presence of hemosiderin in either the macrophages or follicular cells. The cohort consisted of 165 patients with fine needle aspiration (FNA) and histologic follow-up of either goiter (101), follicular adenoma (47), or follicula

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Rituraj, Kumar Akhalesh, and Kumar Singh Pradeep. "Observational Prospective Assessment of the Cyto-Histopatholo gical Correlation in Thyroid Lesions." International Journal of Pharmaceutical and Clinical Research 14, no. 3 (2022): 396–401. https://doi.org/10.5281/zenodo.13845414.

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<strong>Aim: </strong>To correlate cytological and histopathological finding in thyroid lesions. <strong>Material & Methods: </strong>This was an observational Prospective study was conducted in the Department of pathology, Government Medical College, Bettiah, Bihar, India, over a period of one year. <strong>Results: </strong>Total number of cytological diagnoses was 150. In the present study among 150 patients, nodular / colloid goiter was most common lesions accounting for 81 cases (54%) followed by Multinodolar goiter which were 31 cases (20.7%). <strong>Co

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Gujrathi, Atishkumar, Yogesh Paikrao, and Neha Shende. "Clinicopathological Study of Thyroid Masses in Tertiary Care Centre." International Journal of Pharmaceutical and Clinical Research 16, no. 9 (2024): 1110–16. https://doi.org/10.5281/zenodo.13964187.

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<strong>Background: </strong>Thyroid swellings are very frequently encountered in ENT practice, ranging from a simple nodule to a malignant tumor. Disorder of structure of thyroid gland, due to various etiological factors, will give rise to swelling in the neck region. Clinical signs and symptoms are inadequate to diagnose thyroid disorders as similar presentations are seen in various thyroid disorders. So, this study of thyroid swellings was done to know different clinical presentations, age and sex distribution, correlation between thyroid swellings and thyroid function tests, analyze v

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Agarwal, Akshay, Shilpi Sahu, and Reeta Dhar. "Unusual case of a midline neck swelling in a fifty year old female." International Journal of Otorhinolaryngology and Head and Neck Surgery 2, no. 3 (2016): 157. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20162182.

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<p class="abstract">Goitrous enlargement of the thyroid can present as a massive enlargement of the neck. It can be so huge as to obscure detection of an underlying malignancy. Poorly differentiated carcinoma of the thyroid gland is very rare. A 50 year old female patient who was diagnosed preoperatively as having colloid goiter underwent near total thyroidectomy was diagnosed with poorly differentiated thyroid carcinoma on histopathological examination. This case report highlights the various architectural patterns, azzopardi phenomenon with emphasis on immunohistochemical stains and an

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