Log in

Relevant bibliographies by topics / Thyroid hormones/metabolism / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Thyroid hormones/metabolism.

Dissertations / Theses on the topic 'Thyroid hormones/metabolism'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 46 dissertations / theses for your research on the topic 'Thyroid hormones/metabolism.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Boone, Lindsey R. "Thyroid Hormone Regulation of Cholesterol Metabolism." [Tampa, Fla] : University of South Florida, 2009. http://purl.fcla.edu/usf/dc/et/SFE0003089.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Rippamonti, Jessica D. "The Role of Thyroid Hormone on the Development of Endothermy in White Leghorn Chickens (Gallus gallus)." Thesis, University of North Texas, 2018. https://digital.library.unt.edu/ark:/67531/metadc1248477/.

Full text

Abstract:

As chickens hatch, there is a rapid change in their physiology and metabolism associated with attaining endothermy. It is thought that thyroid hormones (TH) play a major role in regulating developmental changes at hatching. In birds, TH regulates skeletal muscle growth, which has a direct impact on the chick's ability to thermoregulate via shivering thermogenesis. To better understand the role of TH in the timing of hatching, development of thermogenic capacity, and metabolic rate, we manipulated plasma TH levels in chicken embryos beginning at 85% development (day 17 of a 21 day incubation

APA, Harvard, Vancouver, ISO, and other styles

3

Sirsat, Tushar S. "The Role of Thyroid Hormone across Avian Development Spectrum: Investigations on Systemic Development, Metabolism and Ontogeny of Endothermy." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc1011746/.

Full text

Abstract:

Achievement of endothernic capacity is vital for independence from ambient temperature changes, sustained activity, optimal biochemical reactions and optimization of parental care. During early avian development, the core tenets of transition from ectothermy to endothermy are development of metabolic capacity (oxygen consumption, mitochondrial bioenergetics), enhanced cardiovascular function (heart rate and cardiac output), pulmonary ventilation and thermogenic capacity. Thyroid hormones, particularly T3, are key metabolic regulators of basal metabolism, thermogenesis, pulmonary ventilation an

APA, Harvard, Vancouver, ISO, and other styles

4

Underhill, Brian Kimball. "The influence of Leptin on metabolic expenditure and thermogenesis during thyroid hormone (T₃) suppression in the obese (OB/OB) mouse." CSUSB ScholarWorks, 2000. https://scholarworks.lib.csusb.edu/etd-project/1767.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Billon, Cyrielle. "Hormones thyroïdiennes et désordres métaboliques." Thesis, Lyon, École normale supérieure, 2012. http://www.theses.fr/2012ENSL0720.

Full text

Abstract:

Les hormones thyroïdiennes jouent un rôle dans de nombreux processus métabolique tels que le développement, la croissance et le contrôle du métabolisme. Les HT se fixent sur leurs récepteurs nucléaires, les TR (TRalpha et beta). Ces TR sont des facteurs de transcription dont l’activité est contrôlée par la fixation de leur ligand, ils appartiennent à la super famille des récepteurs nucléaires d’hormone. Au cours de ma thèse je me suis intéressée aux rôles des TR dans deux contextes particuliers. Dans un premier temps, j’ai pu mettre en évidence le rôle de TRbeta dans la régulation du métabolis

APA, Harvard, Vancouver, ISO, and other styles

6

Amorim, Beatriz de Souza. "Papel do TR na termogênese induzida pela dieta." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/42/42131/tde-19052010-130712/.

Full text

Abstract:

O hormônio tireoideano (T3) desempenha papel importante no desenvolvimento, no crescimento e no metabolismo celular. Um dos seus principais efeitos é a ativação do metabolismo basal, contribuindo de forma importante com a regulação do peso corporal, enquanto diminui os níveis plasmáticos de triglicérides e colesterol. A ativação seletiva do receptor <font face=\"Symbol\">&#946 para o hormônio tireoideano (TR) por meio de agonistas seletivos reduziu níveis séricos de colesterol além de aumentar o metabolismo sem causar efeitos indesejáveis sobre o coração, osso ou músculo esquelético. Estes dad

APA, Harvard, Vancouver, ISO, and other styles

7

Clark, Catherine Renee. "Thyroid hormone influence on oxygen consumption rates, body mass, and lipid metabolism in mice with noninsulin dependent diabetes mellitus." CSUSB ScholarWorks, 1995. https://scholarworks.lib.csusb.edu/etd-project/1025.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Lino, Caroline Antunes. "O sistema ubiquitina-proteassoma no modelo de hipertrofia cardíaca induzida por hormônio tireoidiano." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/42/42131/tde-13032014-162752/.

Full text

Abstract:

Disfunções da glândula tireóide são, frequentemente, associadas a manifestações cardiovasculares e, em situações de hipertireoidismo, o coração hipertrofia. A hipertrofia cardíaca (HC) consiste em uma resposta adaptativa caracterizada pelo aumento de síntese de proteínas estruturais. O Sistema Ubiquitina Proteassoma (UPS) corresponde ao principal mecanismo de proteólise intracelular e crescentes evidências sugerem seu envolvimento no desenvolvimento da HC. O objetivo do presente estudo foi avaliar a modulação do UPS no tecido cardíaco de animais submetidos ao hipertireoidismo. Os resultados re

APA, Harvard, Vancouver, ISO, and other styles

9

Kalousek, A. Kay. "The effect of intraperitoneally administered thyroxine, thiidothyronine and iopanoic acid on the in vivo and in vitro oxygen consumption rates of normal (C57BL/KsJ DB/M) and diabetic (C57BL/KsJ DB/DB) mice." CSUSB ScholarWorks, 1986. https://scholarworks.lib.csusb.edu/etd-project/363.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Martins, Gisele Miyamura. "Avaliação do efeito do hormônio tireoideano na estrutura e fisiologia óssea de camundongos com inativação do Gene do adrenoceptor a2A." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/42/42131/tde-12062013-083322/.

Full text

Abstract:

Um dos mais importantes achados dos últimos anos foi o de que o remodelamento ósseo está sujeito ao controle do SNC, com o SNS agindo como efetor periférico. Um estudo do nosso grupo demonstrou que camundongos <font face=\"Symbol\">a2A/<font face=\"Symbol\">a2C-AR-/- apresentam um fenótipo de alta massa óssea, como também são resistentes à osteopenia induzida pelo excesso de hormônio HT. Com o intuito de verificar a participação do <font face=\"Symbol\">a2A-AR-/- nestes processos, tivemos como objetivos: caracterizar o fenótipo ósseo de camundongos <font face=\"Symbol\">a2A-AR-/- e avaliar o e

APA, Harvard, Vancouver, ISO, and other styles

11

Berger, Bruno da Rocha. "Efeitos do tratamento com tiroxina no remodelamento cardíaco pós-infarto agudo do miocárdio e em parâmetros de estresse oxidativo." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/54950.

Full text

Abstract:

O infarto agudo do miocárdio (IAM) é um evento que acomete milhares de pessoas ao redor do mundo. Após o IAM são desencadeados diversos processos, como alterações na expressão de proteínas envolvidas na contratilidade cardíaca e no remodelamento cardíaco após o IAM, bem como o desequilíbrio no estado redox da célula, que podem levar a um grave prognóstico. A utilização dos hormônios da tireoide vem sendo amplamente estudada na tentativa de desenvolver um método terapêutico eficiente para o tratamento do IAM. Desta forma, o objetivo deste estudo foi verificar os efeitos da tiroxina (T4) sobre a

APA, Harvard, Vancouver, ISO, and other styles

12

Gothie, Jean-David. "Influence de la signalisation thyroïdienne et du métabolisme mitochondrial sur le choix de destin des cellules souches neurales de la zone sous-ventriculaire chez la souris adulte." Thesis, Paris, Muséum national d'histoire naturelle, 2017. http://www.theses.fr/2017MNHN0023.

Full text

Abstract:

Le cerveau adulte des mammifères conserve sa capacité à générer de nouvelles cellules cérébrales à partir de cellules souches neurales (CSNs), principalement localisées dans deux régions cérébrales spécifiques, l'hippocampe et la zone sous-ventriculaire (SVZ). Ce processus, appelé neurogenèse, permet la formation de nouveaux neurones et de nouvelles cellules gliales (astrocytes et oligodendrocytes). Différents signaux contrôlent la prolifération et la différenciation des CSNs. Parmi ces signaux, les hormones thyroïdiennes (HTs) sont impliquées dans la prolifération des CSNs de la SVZ et dans l

APA, Harvard, Vancouver, ISO, and other styles

13

Boumaza, Houda. "Etude métabolomique par résonance magnétique nucléaire de pathologies associées à la signalisation thyroïdienne chez la souris." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSEN003/document.

Full text

Abstract:

La métabolomique par résonance magnétique nucléaire (RMN) permet d’étudier laréponse métabolique globale d’un système biologique à un stimulus ou un événementphysiopathologique (maladie, manipulation génétique, etc.). Cette discipline connaît un essorimportant dans la recherche clinique et biologique, et constitue ainsi un outil à fort potentielpour la découverte de biomarqueurs de maladies, et l’étude de la fonction des gènes.Cette thèse est dédiée à l’application de la métabolomique par RMN à hauts champspour l’étude des pathologies associées à la signalisation thyroïdienne chez la souris. L

APA, Harvard, Vancouver, ISO, and other styles

14

Gullberg, Hjalmar. "Thyroid hormone receptors in liver metabolism /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-190-x/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Jugo, Rebecca. "Thyroid hormone metabolism in the hematopoietic system." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12436.

Full text

Abstract:

Thesis (M.A.)--Boston University<br>Thyroid hormones are iodinated compounds that are critical to differentiation, apoptosis, and cellular processes in virtually every vertebrate cell. The thyroid gland produces mostly thyroxine (T4) and also 3',3,5-triiodothyronine (T3). T4 acts as a "prehormone" and is converted in the periphery into the more physiologically active T3 via deiodination. Deiodination is also the process by which thyroid hormones are inactivated and thyroid hormone balance is maintained. Types 1 (Dl) and 2 (D2) deiodinase activate T4 into T3. Conversely, inactivation is accompl

APA, Harvard, Vancouver, ISO, and other styles

16

Gurgel, Maria Helane Costa. "Marcadores de risco cardiovascular em indivíduos com infarto do miocárdio precoce e em seus familiares de primeiro grau." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-06012016-113510/.

Full text

Abstract:

INTRODUÇÃO: O Infarto agudo do miocárdio (IAM) é infrequente em indivíduos jovens (<45 anos) e está associado à história familiar precoce de doença cardiovascular.OBJETIVO: O presente estudo descreveu o perfil sócio-demográfico e os fatores de risco cardiovascular de indivíduos com diagnóstico de IAM < 45 anos de idade e seus familiares de primeiro grau. Avaliou-se também a relação de parâmetros clínico-laboratoriais de acordo com a extensão angiográfica da doença arterial coronária (DAC) dos casos índices (doença uniarterial vs. multiarterial) e dos seus respectivos familiares.MÉTODOS: Estudo

APA, Harvard, Vancouver, ISO, and other styles

17

TALASILA, PHANI KUMAR. "NOVEL THYROID HORMONE TARGET GENES IN THE LIVER, AND THEIR ROLES IN THYROID HORMONE SIGNALING AND PHYSIOLOGY." Kent State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=kent1347474067.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Gregory, Lisa G. "Induction of rat hepatic thyroid hormone metabolism by microsomal enzyme inducers : role in thyroid homeostasis." Thesis, University of Aberdeen, 2000. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602034.

Full text

Abstract:

Many drugs and xenobiotics cause alterations in thyroid hormone homeostasis by increasing iodothyronine metabolism and hence clearance. Consequently thyroid stimulating hormone (TSH) release is increased, which results in thyroid toxicity in rodent toxicity tests. The aim of this study was to investigate a range of microsomal enzyme inducers for their ability to increase hepatic thyroid hormone metabolism. Induction of UGT activity has been well characterised. Therefore this project focused on induction of deiodination both in vivo and in vitro. In addition to increasing UDP-glucuronosyltransf

APA, Harvard, Vancouver, ISO, and other styles

19

Hall, Jessica Ann. "Thyroid Hormone and Insulin Metabolic Actions on Energy and Glucose Homeostasis." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11663.

Full text

Abstract:

Faced with an environment of constantly changing nutrient availability, mammals have adapted complex homeostatic mechanisms to maintain energy balance. Deviations from this balance are largely corrected through a concerted, multi-organ effort that integrates hormonal signals with transcriptional regulatory networks. When these relationships are altered, as with over-nutrition and insulin resistance, metabolic disease ensues. Here, I present data concerning two distinct transcriptional pathways--one for thyroid hormone (TH) and one for insulin--that confer hormone responsiveness on metabolic ge

APA, Harvard, Vancouver, ISO, and other styles

20

Carriero, Rosaria. "Some factors affecting cortisol and thyroid hormone metabolism in the maternal-fetal placental unit." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=65938.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Kates, Anna-Lisa. "Thyroid hormone metabolism in brown adipose tissue of lean and genetically obese (OBOB) mice." Thesis, University of Ottawa (Canada), 1989. http://hdl.handle.net/10393/21547.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Mitchell, Julie H. "Selenium and iodine deficiency : effects on selenoprotein expression and thyroid hormone metabolism in the rat." Thesis, University of Aberdeen, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296019.

Full text

Abstract:

The aims of the work described in this thesis, were to develop concurrent selenium and iodine deficiencies in rats at different stages of maturity and to study the effects on selenoprotein expression, thyroid hormone metabolism, and brain biochemistry and development. The brain and thyroid gland are able to retain selenium at the expense of the liver when dietary supplies of the micronutrient are limited. Within the brain and thyroid, available selenium is primarily directed towards the synthesis of ID-I and ID-II. The lack of change or increase in thyroidal ID-I activity, in contrast with the

APA, Harvard, Vancouver, ISO, and other styles

23

Prats, Puig Anna. "Implicaciones de la adiponectina de alto peso molecular en el eje tiroideo y el metabolismo óseo." Doctoral thesis, Universitat de Girona, 2012. http://hdl.handle.net/10803/83572.

Full text

Abstract:

Adiponectin is a protein secreted by adipose tissue which possesses insulin-sensitivity and anti-atherosclerotic properties. In this work, we will study if high molecular weight adiponectin is a key molecule in the association between energy metabolism, thyroid axis and bone metabolism in children. To this end, we studied a population of 234 asymptomatic Caucasian children. A sample of blood was also collected to quantify HMW adiponectin, thyroid hormones, bone markers, vitamin D and sFASN. We also obtained 6 biopsies of visceral adipose tissue. The results derived from this study show a posi

APA, Harvard, Vancouver, ISO, and other styles

24

Teixeira, Marilia Bianca Cruz Grecco. "Avaliação do efeito do hormônio tireodiano na estrutura e fisiologia óssea de camundongos com inativação do gene do adrenoceptor α2C." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/42/42131/tde-07122015-153223/.

Full text

Abstract:

Dados mostram que a estimulação do Sistema Nervoso Simpático (SNS) induz osteopenia via receptor β2-adrenérgico, que é expresso no osso. Porém, um estudo recente demonstrou que camundongos knockouts (KO) para os receptores adrenérgicos α2A e α2C (α2A/α2C-AR-/-) apresentam alta massa óssea, mesmo com hiperatividade simpática. Além disso, esses camundongos são resistentes à osteopenia induzida pelo excesso de hormônio tireoidiano. Esses achados sugerem que o α2A e/ou α2C-AR também possam mediar as ações do SNS no esqueleto e que esses receptores estão env

APA, Harvard, Vancouver, ISO, and other styles

25

Hotz, Christine. "Effects of dietary selenium depletion and of dietary selenium and iodine interactions on thyroid hormone metabolism of rat." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1996. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/mq23345.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Pietzner, Maik [Verfasser]. "Comprehensive metabolic characterization of thyroid hormone action on human metabolism in population-based and experimental studies / Maik Pietzner." Greifswald : Universitätsbibliothek Greifswald, 2017. http://d-nb.info/1133041094/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Jun, Lucy Soo Yon. "Thyroid hormone-regulated skeletal muscle Glut4 glucose transporter trafficking during fasting in diet-induced obesity and insulin resistance." CSUSB ScholarWorks, 2005. https://scholarworks.lib.csusb.edu/etd-project/2869.

Full text

Abstract:

This thesis project will investigate the effects of fasting on the serum levels of two key regulatory hormones, insulin and thyroid hormone (T3) and the effects of these hormones on the trafficking of Glut4 on soleus muscle.

APA, Harvard, Vancouver, ISO, and other styles

28

Johansson, Catarina. "Physiological changes in mice deficient in different subtypes of thyroid hormone receptors : a focus on studies of heart and muscle /." Stockholm, 1999. http://diss.kib.ki.se/1999/19990429joha/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Farhat, Amani. "In ovo Effects of Tris(1-chloro-2-propyl) phosphate (TCPP) and Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) Flame Retardants on Chicken Embryo Toxicity and Gene Expression." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/30243.

Full text

Abstract:

Tris(1-chloro-2-propyl) phosphate (TCPP) and tris(1,3-dichloro-2-propyl) phosphate (TDCPP) are added to polyurethane foams in a variety of industrial and consumer products to prevent flame ignition. The gradual release of these flame retardants (FRs) from such products leads to contamination of various abiotic and biotic media, including wild birds. Recent studies demonstrated endocrine-disrupting effects of TCPP and TDCPP, including alteration of circulating thyroid hormone (TH) levels. The TH-pathway is essential for normal growth and development in birds. There are limited data on the toxic

APA, Harvard, Vancouver, ISO, and other styles

30

Mezaroba, Deise Fátima. "Efeitos da dieta hipoproteica-hiperglicídica sobre o metabolismo desiodativo e as ações periféricas dos hormônios tireóideos." Universidade Federal de Mato Grosso, 2015. http://ri.ufmt.br/handle/1/690.

Full text

Abstract:

Submitted by Valquíria Barbieri (kikibarbi@hotmail.com) on 2018-04-18T21:12:08Z No. of bitstreams: 1 DISS_2015_Deise Fátima Mezaroba.pdf: 1567664 bytes, checksum: 67bbe66382033d0b60709a1c450df069 (MD5)<br>Approved for entry into archive by Jordan (jordanbiblio@gmail.com) on 2018-04-27T17:30:42Z (GMT) No. of bitstreams: 1 DISS_2015_Deise Fátima Mezaroba.pdf: 1567664 bytes, checksum: 67bbe66382033d0b60709a1c450df069 (MD5)<br>Made available in DSpace on 2018-04-27T17:30:42Z (GMT). No. of bitstreams: 1 DISS_2015_Deise Fátima Mezaroba.pdf: 1567664 bytes, checksum: 67bbe66382033d0b60709a1c450df069

APA, Harvard, Vancouver, ISO, and other styles

31

Lehmphul, Ina. "Zelluläre Wirkung, Wirkmechanismen und Nachweisverfahren von Schilddrüsenhormonen und ihren Metaboliten." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2015. http://dx.doi.org/10.18452/17434.

Full text

Abstract:

Schilddrüsenhormone (TH) regulieren Metabolismus und Energiestoffwechsel. Der TH‐Metabolit (THM) 3,5‐T2 (3,5‐Diiod‐L‐Thyronin) aktiviert Fett‐Oxidation und mitochondriale Atmung. Der THM 3‐Iodothyronamin (3‐T1AM) beeinflusst zusätzlich glukoregulatorische Prozesse. THM können zur Reduktion von Körperfett beitragen. Um 3,5‐T2 im humanen Serum nachzuweisen sollte ein Immunoassay aufgebaut, validiert und angewendet werden. In intakten hepatozellulären (HepG2) sowie pankreatischen ß‐Zellen (MIN6) sollte untersucht werden ob THM durch Modulation der mitochondrialen Aktivität die zelluläre Substra

APA, Harvard, Vancouver, ISO, and other styles

32

Roques, Beatrice. "Bases mécanistiques des effets d'un insecticide agrovétérinaire, le fiproni, et/ou de ses métabolites sur la fonction thyroïdienne chez le rat." Thesis, Toulouse, INSA, 2012. http://www.theses.fr/2012ISAT0029/document.

Full text

Abstract:

Le fipronil, insecticide largement utilisé, est un perturbateur thyroïdien chez le rat modulant le catabolisme hépatique des hormones thyroïdiennes. Ses effets chez le mouton, considéré comme un modèle plus pertinent que le rat pour étudier une régulation de la fonction thyroïdienne chez l'Homme, sont plus limités. Le but de cette thèse était de caractériser au niveau hépatique le mode d'action du fipronil sur la fonction thyroïdienne en s'intéressant 1) au rôle potentiel du principal métabolite du fipronil formé in vivo, le fipronil sulfone, et 2) aux différences interspécifiques de métabolis

APA, Harvard, Vancouver, ISO, and other styles

33

Fonseca, Tatiana de Lourdes. "Interação do sistema nervoso simpático com o hormônio tireoideano na regulação da massa e metabolismo ósseos." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42131/tde-25092009-162113/.

Full text

Abstract:

Sabe-se que a ativação do Sistema Nervoso Simpático (SNS) induz osteopenia via adrenoceptores b2 (b2-AR). Para investigar se o hormônio tireoideano (HT) interage com o SNS para regular a massa óssea, estudamos o efeito do HT em associação com isoproterenol ou propranolol (agonista e antagonista b-adrenérgicos) e avaliamos o efeito do HT em camundongos com elevado tônus simpático, devido à dupla inativação gênica do a2A-AR e a2C-AR (a2A/a2C-AR-/-), autorreceptores que inibem a liberação de noradrenalina. Vimos que esses animais apresentam um fenótipo de alta massa óssea, apesar do elevado tônus

APA, Harvard, Vancouver, ISO, and other styles

34

Papi, Bianca Neofiti. "Avaliação da interação do hormônio tireoidiano com o sistema nervoso simpático, via receptor Beta2-adrenérgico, na regulação da massa e metabolismo ósseos." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-28092018-090735/.

Full text

Abstract:

O hormônio tireoidiano (HT) é essencial para o desenvolvimento, maturação e metabolismo ósseos, enquanto que o sistema nervoso simpático (SNS) é, também, um potente regulador do remodelamento ósseo. Demonstrou-se que SNS regula negativamente a massa óssea, agindo via receptores ?2-adrenérgicos (?2-AR), expressos em osteoblastos. O nosso grupo demonstrou que os receptores ?2 adrenérgicos (?2-AR) também medeiam ações do SNS no esqueleto e que são expressos em osteoblastos, osteócitos, condrócitos e osteoclastos. Considerando-se que o HT interage com o SNS para regular uma série de processos fisi

APA, Harvard, Vancouver, ISO, and other styles

35

Queiroz, Márcia Silva. "Efeito do hormônio tireoidiano sobre a expressão do RNAm da proteína desacopladora de prótons 3 (UCP3) em miocárdio e músculo esquelético de ratos." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-09102014-120009/.

Full text

Abstract:

INTRODUÇÃO: As proteínas desacopladoras de prótons (UCPs: uncoupling proteins) pertencem à família dos transportadores mitocondriais H+/ácidos graxos e têm distribuição diferenciada nos tecidos. Sabe-se que a UCP1 é responsável pela termogênese, mas o exato papel fisiológico da UCP2 e UCP3 ainda não está completamente estabelecido. Os hormônios tireoideanos (T3 e T4) estimulam a expressão da UCP3 em músculo cardíaco e esquelético, no entanto o mecanismo pelo qual exercem esse efeito não é conhecido. Este projeto visa avaliar se as alterações na expressão gênica da UCP3 são relacionadas a efeit

APA, Harvard, Vancouver, ISO, and other styles

36

Berno, Luciane Isabel. "Estudo da ação de diferentes proporções de torta de castanha do brasil sobre a concentração dos hormonios da tireoide, niveis sanguineos de glutationa reduzida e alguns parametros metabolicos em ratos Wistar." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/255051.

Full text

Abstract:

Orientador: Mario Roberto Marostica Junior<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos<br>Made available in DSpace on 2018-08-14T20:32:06Z (GMT). No. of bitstreams: 1 Berno_LucianeIsabel_M.pdf: 1103514 bytes, checksum: 7482258c3423d699ee03f85080189d7a (MD5) Previous issue date: 2009<br>Resumo: O objetivo do presente trabalho foi o de avaliar os efeitos do selênio oriundo da torta de castanha do Brasil sobre a concentração dos hormônios da tireóide, níveis de glutationa reduzida e alguns parâmetros bioquímicos de ratos Wistar decorrentes

APA, Harvard, Vancouver, ISO, and other styles

37

Myrelid, Åsa. "Down syndrome : Growth and endocrine impact." Doctoral thesis, Uppsala universitet, Pediatrik, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-106756.

Full text

Abstract:

Down syndrome (DS) is associated with psychomotor retardation, short stature and endocrine dysfunction. Statural growth is a well-known indicator of health. The growth in DS differs markedly from that of other children and there is a 20 cm reduction of final height as compared to target height. We developed growth charts specific for Swedish children with DS, in order to facilitate early diagnosis of concomitant diseases that influence growth. The growth charts are available for paediatricians and child health care professionals in Sweden. The mechanism underlying the impaired growth in DS is

APA, Harvard, Vancouver, ISO, and other styles

38

Mouillet, Laurence. "Iodothyronines et métabolisme énergétique chez le caneton en croissance au froid." Lyon 1, 2000. http://www.theses.fr/2000LYO1T168.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Piehl, Susanne. "The roles of deiodinases in thyronamine biology." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2008. http://dx.doi.org/10.18452/15795.

Full text

Abstract:

3-Jodthyronamin (3-T1AM) und Thyronamin (T0AM) sind endogene Signalmoleküle, die eine große strukturelle Ähnlichkeit zu Schilddrüsenhormonen aufweisen, allerdings die klassischen Wirkungen des aktiven Schilddrüsenhormons 3,5,3’-Trijodthyronin (T3) antagonisieren. In der vorliegenden Arbeit wurde untersucht, ob Thyronamine (TAMs) Substrate von Dejodasen (Dio1, Dio2, Dio3) sind. Die TAMs wurden mit isozymspezifischen Dio-Präparationen inkubiert. Die Dejodierungsprodukte wurden mittels Hochleistungsflüssigkeitschromatographie und Tandemmassenspektrometrie (LC-MS/MS) analysiert. Mit Präparatione

APA, Harvard, Vancouver, ISO, and other styles

40

Meyer, Franziska. "Zelltyp-spezifische Inaktivierung von Mct8 in Gehirnzellen." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2017. http://dx.doi.org/10.18452/17690.

Full text

Abstract:

Der Monocarboxylattransporter 8 (Mct8) ist ein spezifischer Schilddrüsenhormon (SDH)-Transporter. MCT8-Mutationen führen zu einer psychomotorischen Retardierung in Kombination mit abnormalen SDH-Serumkonzentrationen. Das konstitutiv Mct8-defiziente Mausmodell repliziert den endokrinologischen, jedoch nicht den humanen neurologischen Phänotyp. Um die Hypothese eines stark beeinträchtigten T3-Transportes speziell in Neuronen als Ursache zu untersuchen, wurde das Neuron-spezifische Mct8-defiziente Mausmodell (CamK-Cre;Mct8fl/fl) generiert. Neben einer funktionalen, Mct8-exprimierenden Blut-Hirn-S

APA, Harvard, Vancouver, ISO, and other styles

41

Höfig, Carolin. "Establishment, validation and application of immunological and LC-MS/MS-based detection methods to study the role of human aromatic L-amino acid decarboxylase as an enzyme potentially involved in thyronamine biosynthesis." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2012. http://dx.doi.org/10.18452/16645.

Full text

Abstract:

Thyronamine (TAM) sind eine neue Molekülklasse, die endokrinologische und metabolische Prozesse miteinander vereinen. Der biologisch aktive Metabolit 3-Iod-L-Thyronamin (3-T1AM) wird durch eine kombinierte Deiodierung und Decarboxylierung von Schilddrüsenhormonen (TH) gebildet. Existierende Methoden zum Nachweis und zur Quantifizierung von 3-T1AM im menschlichen Serum sind immer noch umstritten. Auch die an der Biosynthese vermutlich beteiligte TH-Decarboxylase konnte noch nicht identifiziert werden. Für die Identifizierung und Quantifizierung von TH und TAM Profilen wurde die Flüssigchromatog

APA, Harvard, Vancouver, ISO, and other styles

42

Manna, Debasish. "Deiodination of Thyroid Hormones by Iodothyronine Deiodinase Mimics." Thesis, 2013. http://etd.iisc.ernet.in/2005/3304.

Full text

Abstract:

Thyroxine is the main secretory hormone of thyroid gland and it is produced in thyroglobulin by thyroid peroxidase/hydrogen peroxide/iodide system. After biosynthesis and secretion of thyroxine, it undergoes multiple metabolic reactions. The most important metabolic pathway is the stepwise deiodination from the inner ring or outer ring. Removal of one of the outer ring or phenolic ring iodines of biologically less active T4, leads to the formation of 3,5,3'-triiodothyronine or T3, a compound which is biologically more active. On the other hand, removal of one of the inner ring or tyrosyl ring

APA, Harvard, Vancouver, ISO, and other styles

43

Kohel, Kathryn A. "The role of the intestine in the metabolism of thyroid hormones and in the regulation of thyroidal status in the rainbow trout, Oncorhynchus mykiss." 2004. http://hdl.handle.net/1993/16278.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Carvalho, Joana Patrícia Mendes de. "Síndrome de Resistência às Hormonas Tiroideias: Breve Revisão e Casuística do Serviço de Endocrinologia, Diabetes e Metabolismo do Centro Hospitalar e Universitário de Coimbra." Master's thesis, 2017. http://hdl.handle.net/10316/81819.

Full text

Abstract:

Trabalho de Projeto do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: A síndrome de resistência às hormonas tiroideias (SRHT) é uma entidade clínica rara, com uma incidência estimada de um caso em cada 40 000 nascimentos. A hereditariedade é predominantemente autossómica dominante, resultando a síndrome maioritariamente de mutações do gene THRB . Os aspetos mais características desta síndrome são os níveis elevados de T4L e T3L e níveis de TSH normais ou aumentados. O diagnóstico baseia-se na clínica e nos doseamentos hormonais e é confirmado através de estud

APA, Harvard, Vancouver, ISO, and other styles

45

Roberts, Simon Clay. "PBDE Metabolism and Effects on Thyroid Hormone Regulation in Human Astrocytes." Diss., 2014. http://hdl.handle.net/10161/9394.

Full text

Abstract:

<p>Polybrominated diphenyl ether (PBDE) flame retardants are ubiquitous contaminants in the environment due to their heavy usage in plastics, foam, and textiles to comply with flammability standards from the 1970s through the late 2000s. Due to their toxicity and persistence in the environment, two of the three PBDE commercial mixtures (PentaBDE and OctaBDE) were banned by the Stockholm Convention on Persistent Organic Pollutants in 2009. The DecaBDE commercial mixture, which consists primarily of the fully brominated congener BDE-209, has been banned or phased out in the United States and Eur

APA, Harvard, Vancouver, ISO, and other styles

46

Noyes, Pamela. "Polybrominated Diphenyl Ether (PBDE) Flame Retardants: Accumulation, Metabolism, and Disrupted Thyroid Regulation in Early and Adult Life Stages of Fish." Diss., 2013. http://hdl.handle.net/10161/7117.

Full text

Abstract:

<p>Polybrominated diphenyl ethers (PBDEs) are a class of brominated flame retardant chemicals that are added to plastics, electronic components, furniture foam, and textiles to reduce their combustibility. Of the three commercial mixtures historically marketed, only DecaBDE, which is constituted almost entirely (~97%) of the fully brominated congener decabromodiphenyl ether (BDE-209), continues to be used in the U.S. today. While decaBDE is scheduled for phase-out in the U.S. at the end of 2013, exposures to BDE-209 and other PBDEs will continue into the foreseeable future as products that con

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!