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Dissertations / Theses on the topic 'Thyroid malignancy'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Shen, Daniel Hueng-Yuan. "Sodium iodide symporter based strategy for treatment of thyroid and non-thyroid malignancy." Connect to this title online, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1047493162.

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Thesis (Ph. D.)--Ohio State University, 2003.<br>Title from first page of PDF file. Document formatted into pages; contains xiv, 133 p.; also includes graphics Includes bibliographical references (p. 116-133). Available online via OhioLINK's ETD Center

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2

Goukassian, Ilona Davidovna. "In vivo and ex vivo techniques using elastic scattering spectroscopy for diagnosis of malignancy in the thyroid gland." Thesis, Boston University, 2011. https://hdl.handle.net/2144/30916.

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Thesis (M.A.)--Boston University, 2011.<br>OBJECTIVE: Thyroid cancer is the most common endocrine malignancy and patients presenting with thyroid nodules often undergo surgery solely for diagnostic purposes. The goal of our study was to examine the accuracy of Elastic Scattering Spectroscopy (ESS) in distinguishing between benign and malignant thyroid nodules in fresh ex vivo specimens and to design an in vivo ESS probe and device, manufacture it and conduct a clinical trial. METHODS: Patients already undergoing thyroidectomy surgery were consented for the ex vivo study. ESS data was o

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3

Martins, Mariana Bonjiorno 1985. "Análise do perfil das proteínas MAGE A3, P53, MDM2 e KAP - 1 na identificação de malignidade e na caracterização de lesões tiroidianas de padrão folicular = Analysis of protein profile MAGE A3, P53, MDM2 and KAP-1 in malignancy identification and in the characterization of thyroid follicular lesions." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310267.

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Orientador: Laura Sterian Ward<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-20T22:18:00Z (GMT). No. of bitstreams: 1 Martins_MarianaBonjiorno_M.pdf: 2775717 bytes, checksum: 1e2d998b43775fd0f5b926acafc0b649 (MD5) Previous issue date: 2012<br>Resumo: As lesões tiroidianas de padrão folicular constituem cerca de 30% das lesões de tiroide e são um grande problema clínico já que incluem condições benignas e malignas. Isso obriga aos pacientes que são candidatos potenciais a realizarem cirurgia, que se mostra d

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4

Thuillier, Philippe. "Optimisation des paramètres de quantification en imagerie TEP pour le diagnostic, l'évaluation thérapeuthique et le pronostic des cancers endocriniens Malignancy rate of focal thyroid incidentaloma detected by FDG PET–CT: results of a prospective cohort study, in Endocrine Connections 6(6), 2017 Diagnostic Value of FDG PET-CT Quantitative Parameters and Deauville-Like 5 Point-Scale in Predicting Malignancy of Focal Thyroid Incidentaloma, in Frontiers in Medicine 6(24), February 2019." Thesis, Brest, 2019. http://www.theses.fr/2019BRES0088.

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L’objectif de ce travail de thèse était de proposer une approche systématique et raisonnée des outils de quantification disponibles en routine clinique et du domaine de la recherche dans la prise en charge des patients atteints d’une tumeur endocrine. Nos résultats font état des limites des paramètres semi-quantitatifs pour faire le diagnostic de malignité d’un ITf fixant au 18FDG-TEP/TDM. Nos données sur l’intérêt des paramètres de textures dans le diagnostic de malignité des tumeurs surrénaliennes nous montrent des performances excellentes de ces indices mais qui n’apparaissent cependant pas

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5

Bakhsh, Ameen. "Molecular characterisation of benign and malignant thyroid dysfunction." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/58408/.

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Nodular thyroid disease is common (prevalence 2-6%) and is a significant risk factor for the development of thyroid cancer. My aim was to apply genome-wide- linkage-analysis to identify the defect in a large kindred with multi-nodular goitre (MNG) of adolescent onset progressing to papillary thyroid cancer (PTC). Genomic DNA from 18 individuals (8 affected) was hybridized to Affymetrix GeneChip® Human Mapping 10K 2.0 Arrays. Results were analysed with Affymetrix GTYPE software to produce a call rate of ~92%. Extensive quality control steps were performed (PLINK, GRR) prior to linkage analysis

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6

Lam, King-yin Alfred, and 林敬賢. "Pathology and molecular biology of malignant thyroid tumours." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B29867824.

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7

Balthasar, Sonja. "Sphingolipid signalling in normal and malignant thyroid cells /." Turku : Painosalama Oy, 2007. http://catalogue.bnf.fr/ark:/12148/cb41077764x.

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8

Ciappuccini, Renaud. "Apport de l'imagerie fonctionnelle par TEMP/TDM et TEP/TDM dans la prise en charge des cancers différenciés de la thyroïde Incremental Value of a Dedicated Head and Neck Acquisition during 18F-FDG PET/CT in Patients with Differentiated Thyroid Cancer Full text links full-text provider logo Actions Favorites Share Page navigation Title & authors Abstract Conflict of interest statement Figures Similar articles Cited by References Related information LinkOut - more resources EJNMMI Res . 2018 Dec 3;8(1):104. doi: 10.1186/s13550-018-0461-x. Optimization of a dedicated protocol using a small-voxel PSF reconstruction for head-and-neck 18 FDG PET/CT imaging in differentiated thyroid cancer 78 Lymph node involvement in head-and-neck and thyroid cancers with digital PET/CT: the impact of ultra-high definition voxels and point-spread function Tumor burden of persistent disease in patients with differentiated thyroid cancer: correlation with postoperative risk-stratification and impact on outcome 133 18F-Fluorocholine PET/CT is a highly sensitive but poorly specific tool for identifying malignancy in thyroid nodules with indeterminate cytology: The Chocolate study PSMA expression in neovasculature of persistent/recurrent differentiated thyroid cancerin the neck: relationship with radioiodine uptake, 18Fluorodeoxyglucose avidity and outcome." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMC424.

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L’imagerie scintigraphique des cancers thyroïdiens différenciés (CTD) présente la particularité d’utiliser deux radiopharmaceutiques, l’iode 131 (131I) et le 18-Fluorodésoxyglucose (18FDG). La fixation de ces traceurs dépend habituellement du degré de différenciation et de l’agressivité de la tumeur. L’objectif de ce travail était d’étudier l’apport de différents aspects techniques et d’instrumentation, à savoir l’imagerie hybride par TEMP/TDM et TEP/TDM, la point-spread function (PSF), la taille des voxels et la technologie TEP digitale, et d’explorer si d’autres traceurs TEP pouvaient présen

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9

Pitchers, Mark Edward. "Expression profiling of matrix metalloproteinases and related enzymes in benign and malignant thyroid disease." Thesis, University of East Anglia, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441557.

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10

Костюченко, Є. В. "Злоякісні новоутворення щитовидної залози: захворюваність, смертність, лікування". Thesis, Сумський державний університет, 2014. http://essuir.sumdu.edu.ua/handle/123456789/36438.

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У останні роки спостерігається тенденція до зростання захворюваності на злоякісні новоутворення (ЗН) в Україні. Актуальними залишаються питання дослідження і розробки нових ефективних методів профілактики і лікування цих захворювань. А для оцінки цієї ефективності та контролю в цілому необхідно постійно проводити дослідження сучасного стану захворюваності, смертності, інших статистичних показників щодо всіх видів ЗН. У даній роботі ми провели таке дослідження щодо ЗН щитовидної залози. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/36438

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11

Giordano, Nicholas Joseph. "Discriminating benign from malignant thyroid nodules in real-time using a novel probe with an integrated elastic scattering spectroscopy biopsy syringe." Thesis, Boston University, 2013. https://hdl.handle.net/2144/12111.

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Thesis (M.A.)--Boston University<br>Background. Thyroid cancer is the most common endocrine malignancy. The current standard of diagnosis, fine needle aspiration biopsy (FNAB) yields indeterminate results for approximately 10–25% of biopsies, necessitating thyroidectomy for diagnosis. Elastic scattering spectroscopy (ESS) is a minimally invasive optical biopsy technique that is sensitive to cellular and subcellular morphological features. We hypothesized that it was feasible to use ESS in vivo to improve our ability to preoperatively differentiate benign from malignant thyroid nodules. Method

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12

Рєзнік, А. В. "Значення кальцифікації у діагностиці злоякісних процесів щитоподібної залози". Thesis, Сумський державний університет, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41712.

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Актуальність. За сумарною частотою у популяції захворювання щитоподібної залози (ЩЗ) виходять на перше місце серед ендокринної патології та зумовлюють клінічні прояви багатьох синдромів та важких розладів. У ЩЗ кальцифікати зустрічаються як при доброякісній, так і за умов злоякісної патології, яка діагностується при ультразвуковому дослідженні органа. Отримана діагностична інформація про кальцифіковані об’єкти у ЩЗ часто пропускається клініцистами, або їй надається мінімальне клінічне значення. Проте існує багато повідомлень про високий ризик поєднання процесів біомінералізації (кальцифікації

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13

Carnes, Nicholas. "Predicting risk of malignancy in patients with indeterminate thyroid nodules." Thesis, 2018. https://hdl.handle.net/2144/31159.

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Thyroid cancer is the most prevalent endocrine cancer (1). The prevalence of palpable thyroid nodules in the general adult population is 4% to 7% (2). Ultrasound imaging detects thyroid nodules in 19%-68% of randomly selected individuals (3). The rate of thyroid cancer in nodules found on US is 4% to 15% (4). In order to evaluate thyroid nodules patients undergo thyroid ultrasonography and, if needed, a fine-needle aspiration biopsy. Of all fine-needle aspiration biopsies, 15-30% are indeterminate on cytology (5). While only 3% of these nodules are malignant on average, a much higher percentag

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14

Makepeace, A. H. "The frequency of thyroid gland invasion in advanced laryngeal malignancy: an audit of total laryngectomy histological specimens." Thesis, 2017. http://hdl.handle.net/10539/23405.

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This dissertation is submitted as a final copy as the University’s Academic and Clinical supervisor<br>Background Thyroid gland involvement in advanced laryngeal malignancies is a rare entity, mostly resulting from direct contiguous spread from anterior and inferior tumours. Reported practice is to perform a hemithyroidectomy at the time of laryngectomy. However, this results in pointless excision of functional tissue and the added morbidity of hypothyroidism post operatively. Aim The aim of this study is twofold: firstly, to assess the frequency of thyroid gland involvement in laryngectomy

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15

Germano, Ana Sofia da Conceição Carreira. "A ecografia na optimização da estratificação do risco de malignidade dos nódulos da tiroide. The role of ultrasound in optimizing the stratification of thyroid nodules’ malignancy risk." Doctoral thesis, 2018. http://hdl.handle.net/10362/39612.

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RESUMO: Contexto O carcinoma da tiroide é uma “epidemia” a nível mundial, sendo significativamente mais prevalente no sexo feminino. Nos últimos anos, por a mortalidade permanecer constante, apesar do aumento exponencial da incidência, tem sido colocada a possibilidade de existência de sobre diagnóstico destas lesões. A ecografia de alta resolução é indiscutivelmente a melhor técnica de imagem para detetar nódulos da tiroide. No entanto, é dependente do operador e ainda não consegue, de forma precisa, diferenciar os raros nódulos malignos dos muito frequentes nódulos tiroideus benignos

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16

Soumya. "Accuracy of core needle biopsy compared to fine needle biopsy for the diagnosis of malignancy in patients with suspected head and neck cancers: A systematic review and meta-analysis of diagnostic test accuracy and comparison of adverse effects." Thesis, 2020. http://hdl.handle.net/2440/126065.

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Objective: The objective of this review was to compare the diagnostic accuracy of core needle biopsy and fine needle aspiration cytology for patients with a head and neck mass for a diagnosis of malignancy using surgical histopathology as a reference test and to compare the risks and adverse events associated with each technique. Introduction: A proportion of head and neck neoplasms are malignant which can only be determined by a tissue diagnosis. Options for tissue biopsy include - surgical biopsy, fine needle aspiration (FNA), and core needle biopsy (CNB). Insufficient tissue for a diagnosis

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17

Hsin-Chang and 蕭信昌. "Diagnostic Value of Ultrasonography to Distinguish Benign from Malignant Lesion in the thyroid Nodules." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/98388484355938099873.

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碩士<br>中山醫學大學<br>醫學研究所<br>100<br>Background:High-frequency sonographic imaging is now widely used in evaluation of the thyroid gland which led to the detection of a large number of non-palpable thyroid nodules in the general population. It has been estimated that 40% to 50% of the population will have a thyroid nodule found incidentally on sonography when performing examination of the neck lymph nodes, carotid arteries or other structures of the neck. Yet only about 5% to 6.5% of these nodules will represent malignant disease on further workup. Biopsy of all incidentally detected thyroid nodule

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18

Aguiar, Ana Rita de Almeida Machado. "Classificação TI-RADS na Estratificação do Risco de Malignidade de Nódulos Tiroideus e sua Abordagem Clínica." Master's thesis, 2018. http://hdl.handle.net/10316/82521.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>This retrospective study was aimed to evaluate the necessity of US-guided fine-needle aspiration biopsy (FNAB) of Thyroid nodules that were submitted to this technique in the Medical Imaging Department of Coimbra Hospital and Universitary Center (CHUC) during the year of 2013, had it been applied the TI-RADS (Thyroid Imaging Reporting and Data System) classification. From a total sample of 379 patients, only 312 thyroid nodules obtained a conclusive diagnosis (283 benign and 29 malignant), from which 272 we

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