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Journal articles on the topic 'Tissu de granulation'

Author: Grafiati

Published: 4 June 2021

Last updated: 8 June 2024

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1

Gangl, Monika. "Les complications associées aux chirurgies de pied." Le Nouveau Praticien Vétérinaire équine 16 (October 2022): 114–19. http://dx.doi.org/10.1051/npvequi/2023001.

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Les chirurgies du pied sont fréquentes en pratique équine, et couvrent tout le spectre d’un simple débridement d’abcès de pied jusqu’aux techniques d’ostéosynthèse. Les complications les plus souvent rencontrées sont l’hémorragie, l’infection, et les problèmes de cicatrisation telles que la déhiscence, la formation d’un tissu de granulation excessif et la déformation de la boîte cornée. L’hémorragie n’impacte qu’exceptionnellement le pronostic vital, mais diminue la visibilité du champ chirurgical. Les infections persistantes et surinfections sont fréquentes, le pied se trouvant à proximité du

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2

Bogdanov, S. B., V. A. Aladina, D. N. Marchenko, et al. "SURGICAL ASPECTS OF FULL-THICKNESS SKIN AUTOGRAFT ENGRAFTMENT ON A GRANULATING WOUND." Innovative medicine of Kuban, no. 2 (June 2, 2020): 41–45. http://dx.doi.org/10.35401/2500-0268-2020-18-2-41-45.

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Background. The paper presents the clinical results of treating patients using full-thickness skin autografts for granulating wounds.Objective. To study the surgical aspects of full-thickness skin autograft engraftment on a granulating wound. Material and methods In traumatology and burn research, to achieve the best cosmetic results, transplantation methods of free full-thickness skin autografts are used. In the Regional Clinical Hospital #1, a method of skin grafting with a full-thickness autograft was developed, which allows to close the defect in the conditions of a purulent wound: granula

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3

Hasan, Masroor, Shafquat Hussain Khundkar, Md Enamul Kabir, and SM Shakwat Hossain. "A comparative study of split thickness skin graft take on chronic wounds with and without surgical removal of granulation tissue from the recipient bed." Journal of Armed Forces Medical College, Bangladesh 9, no. 2 (2015): 49–53. http://dx.doi.org/10.3329/jafmc.v9i2.21826.

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Introduction: In most of the patients with chronic granulating wounds split skin grafting is the preferred option for coverage of the wounds. Split skin grafts may be applied directly on the granulation tissue or it may be applied after complete removal of granulation tissue. Opinions are divided on this issue. Objectives: To compare the skin take between the split thickness skin grafting on chronic wounds after removal and without removal of granulation tissue in the same patient. Methods: This is a longitudinal type of follow up and comparative study and was carried out in the Department of

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Polyovyy, V. P., B. Khorshani, V. V. Petrynych, P. V. Kyfyak, O. V. Tkachuk, and R. I. Sydorchuk. "FEATURES OF THE EARLY PROCESS IN DIABETIC FOOT SYNDROME." Kharkiv Surgical School, no. 2 (April 20, 2020): 21–25. http://dx.doi.org/10.37699/2308-7005.2.2020.04.

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Summary. Diabetic foot syndrome (DFS) is one of the most common surgical diseases. The aim of the study: to determine the features of the wound process in the DFS. Materials and methods. Multimodal pathomorphological study of biopsy material in 120 cases of surgical treatment of DFS was performed. Results and discussion. During the development of the wound process in the DFS, histologically determined reduction of edema, cellular infiltration, microcirculatory disorders in the marginal area of the wound in the dynamics of treatment. It is found in granulation tissue and in th

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Smith, W. K., and A. G. Pfleiderer. "The use of the KTP laser in the management of hypertrophic tracheal mucosa and granulation tissue around Provox® valve protheses." Journal of Laryngology & Otology 117, no. 1 (2003): 60–62. http://dx.doi.org/10.1258/002221503321046667.

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The development of hypertrophic mucosa and granulation tissue around a tracheo-oesophageal fistula voice prosthesis is a commonly encountered problem occurring in 15–20 per cent of patients. Upsizing of the voice prosthesis as well as cautery (silver nitrate and electocautery) are used to counteract this problem to a varying degree of success. The use of the CO2 laser has been mentioned by some authors but details of the method and results have not been published. We report the successful use of the KTP laser for removing such granulations whilst retaining the valve and discuss the reasons why

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6

Bansal, Mohan. "Granular myringitis: current status of management." International Journal of Otorhinolaryngology and Head and Neck Surgery 1, no. 2 (2015): 55. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20150900.

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<p class="abstract"><span lang="EN-US">The Granular Myringitis (GM) is not uncommon though in medical literature it has been reported among the rarer conditions. The aim of this article is to review the clinical features and management of Granular Myringitis (GM). GM is characterized by granulation tissue on the outer surface of the Tympanic Membrane (TM) with or without the involvement of deep bony External Auditory Canal (EAC). The granulations are either localized or diffuse. The granulations over tympanic membrane continue to grow slowly for years. The ensuing fibrosis in patie

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7

Conegero, Celso Ivan, and Renato Paulo Chopard. "Tridimensional architecture of the collagen element in the arachnoid granulations in humans: a study on scanning electron microscopy." Arquivos de Neuro-Psiquiatria 61, no. 3A (2003): 561–65. http://dx.doi.org/10.1590/s0004-282x2003000400007.

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The arachnoid granulations of adult individual of both sexes were studied through scanning electron microscopy. The dura mater and arachnoid meninges of individuals were collected at the Service of Death Verification of São Paulo - USP and fixed in Karnovsky solution. After this period the material was prepared for analysis in electron microscope. Our results demonstrated that the arachnoid granulations are formed by a pedicle, body and apex, being surrounded by a capsule of connective tissue, which in turn is composed of, basically, bundles of collagen fibers that line pores of different shap

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8

Bigbie, R. B., J. Schumacher, S. F. Swaim, R. C. Purohit, and J. C. Wright. "Effects of amnion and live yeast cell derivative on second-intention healing in horses." American Journal of Veterinary Research 52, no. 8 (1991): 1376–82. http://dx.doi.org/10.2460/ajvr.1991.52.08.1376.

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Summary Equine amnion and live yeast cell derivative were evaluated as a biological dressing and as a topical wound medicament respectively, in the treatment of granulating wounds of the distal portion of the limbs of horses. Wounds measuring 2.5 × 2.5 cm were created on the dorsomedial aspect of the metacarpal and metatarsal region of all 4 limbs of 9 horses. Each wound was assigned randomly to 1 of 3 treatment groups: group C, treated with a nonadherent bandage as a control; group A, treated with amnion beneath a nonadherent bandage; and group L, treated with live yeast cell derivative benea

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9

Ghosh, Ajoy Kumar, Noriyasu Hirasawa, Hiroshi Ohtsu, Takehiko Watanabe, and Kazuo Ohuchi. "Defective Angiogenesis in the Inflammatory Granulation Tissue in Histidine Decarboxylase–deficient Mice but not in Mast Cell–deficient Mice." Journal of Experimental Medicine 195, no. 8 (2002): 973–82. http://dx.doi.org/10.1084/jem.20011782.

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We have analyzed the role of histamine in the angiogenesis of the granulation tissue in histidine decarboxylase–deficient (HDC−/−) mice, mast cell–deficient mice (WBB6F1-W/WV), and their corresponding wild-type mice (HDC+/+ and WBB6F1+/+). In HDC+/+ mice, subcutaneous implantation of a cotton thread in the dorsum induced granulation tissue formation with angiogenesis, while the topical injection of antivascular endothelial growth factor (VEGF) IgG strongly suppressed them. In HDC−/− mice which showed lower VEGF levels in the granulation tissue, there was notably less angiogenesis and granulati

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10

Nikonorova, Varvara G., Vladimir V. Krishtop, and Tat’yana A. Rumyantseva. "Granulation Tissue as a Type of Connective Tissue (Review)." Journal of Medical and Biological Research, no. 2 (May 10, 2022): 167–79. http://dx.doi.org/10.37482/2687-1491-z098.

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Currently, there is no consensus among scientists on the place of scar tissue and, in particular, granulation tissue in the classification of fibrous connective tissue. This paper aimed to generalize literature data on the structure and development of fibrous scar tissue. It is demonstrated that granulation tissue is mostly composed of myofibroblasts, along with fibroblasts, as well as old fibroblasts, endothelial cells, and immune cells. Myofibroblasts are characterized by a developed cytoskeleton represented by stress fibers, which ensures active migration of these cells and remodelling of t

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11

Shvets, O. V., Tatiana V. Gaivoronskaya, E. E. Esaulenko, and N. I. Bykova. "Optimization of healing in patients with odontogenic phlegmon of the maxillofacial region." Russian Journal of Dentistry 24, no. 6 (2020): 387–90. http://dx.doi.org/10.17816/1728-2802-2020-24-6-387-390.

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Aim. This study aims to increase the efficiency of the wound process in patients with odontogenic phlegmons of the maxillofacial region by using energotropic and antioxidant agents. Material and methods. The clinical study included 42 patients with odontogenic phlegmons of the maxillofacial region. The patients were divided into two groups: comparison group (patients received traditional treatment) and main group (patients received treatment with Cytoflavin in the treatment regimen). Results. In the main group, the appearance of the first granulations occurred 2.1 times faster (on average on t

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12

Ito, Kiyoshi, Tetsuyoshi Horiuchi, Kiyomitsu Oyanagi, Tetsuo Nomiyama, and Kazuhiro Hongo. "Comparative study of fibrin and chemical synthetic sealant on dural regeneration and brain damage." Journal of Neurosurgery: Spine 19, no. 6 (2013): 736–43. http://dx.doi.org/10.3171/2013.8.spine12998.

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Object Several materials, such as polyethylene glycol (PEG) hydrogel and fibrin glue, have been used to seal dural incisions after brain and spinal surgeries. Although the use of PEG sealant is gaining popularity, it can be associated with postoperative cerebrospinal fluid leakage and infection. However, the reasons for this association are currently unknown. The present study aimed to investigate the effects of PEG sealant and fibrin glue on wound healing and brain damage in vivo. Methods Oval-shaped bone defects and dural defects were created bilaterally over the parietal lobes of 22 Japanes

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13

Higgins, E. M., J. R. Hughes, S. Snowden, and A. C. Pembroke. "Cyclosporin-induced periungual granulation tissue." British Journal of Dermatology 132, no. 5 (2006): 829–30. http://dx.doi.org/10.1111/j.1365-2133.1995.tb00737.x.

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14

Medrek, Sarah K., Donald R. Lazarus, Neda Zarrin-Khameh, Nadia Mohyuddin, and Venkata Bandi. "Obstructive Post-tracheotomy Granulation Tissue." American Journal of Respiratory and Critical Care Medicine 196, no. 5 (2017): e12-e13. http://dx.doi.org/10.1164/rccm.201703-0468im.

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15

Bertone, Alicia L. "Management of Exuberant Granulation Tissue." Veterinary Clinics of North America: Equine Practice 5, no. 3 (1989): 551–62. http://dx.doi.org/10.1016/s0749-0739(17)30574-6.

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16

Wilmink, Jacintha M., and P. René Van Weeren. "Treatment of exuberant granulation tissue." Clinical Techniques in Equine Practice 3, no. 2 (2004): 141–47. http://dx.doi.org/10.1053/j.ctep.2004.08.012.

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17

Sandreva, Tatjana, Anette Bygum, and Vibeke Vestergaard. "Peristomal granulation tissue–like papules." Journal of the American Academy of Dermatology 72, no. 1 (2015): e11-e12. http://dx.doi.org/10.1016/j.jaad.2014.05.066.

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18

HØLUND, BERIT, INGE CLEMMENSEN, PETER JUNKER, and HANS LYON. "FIBRONECTIN IN EXPERIMENTAL GRANULATION TISSUE." Acta Pathologica Microbiologica Scandinavica Series A :Pathology 90A, no. 1-6 (2009): 159–65. http://dx.doi.org/10.1111/j.1699-0463.1982.tb00077_90a.x.

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19

Kocoshis, Samuel A., Gerry Hennies, Kim Klotz, Kathie Yeary, and Philip E. Putnam. "Internal Granulation Tissue of Gastrostomies." American Journal of Gastroenterology 100 (September 2005): S378. http://dx.doi.org/10.14309/00000434-200509001-01039.

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20

Häkkinen, Lari, Hannu Larjava, and Leeni Koivisto. "Granulation tissue formation and remodeling." Endodontic Topics 24, no. 1 (2011): 94–129. http://dx.doi.org/10.1111/etp.12008.

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21

Hirotsu, Kelsey, Swati Kannan, and Shang I. Brian Jiang. "Treatment of Hypertrophic Granulation Tissue." Dermatologic Surgery 45, no. 12 (2019): 1507–16. http://dx.doi.org/10.1097/dss.0000000000002059.

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22

Gniadecki, R., and J. Serup. "Enhancement of the granulation tissue formation in hairless mice by a potent vitamin D receptor agonist – KH 1060." Journal of Endocrinology 141, no. 3 (1994): 411–15. http://dx.doi.org/10.1677/joe.0.1410411.

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Abstract KH 1060 is a 20-epi analogue of 1,25-dihydroxyvitamin D3 and a potent agonist of the vitamin D receptor. Our recent finding that it stimulates glycosaminoglycan synthesis and transforming growth factor-β1 (TGF-β1) expression in normal skin provided a rationale for investigating its influence on the process of wound healing. Normal and betamethasone-impaired granulation tissue formation was studied in a polytetrafluoroethylene dead space model in hairless mice. The application of KH 1060 increased the indexes of fibroplasia and cellularity ([3H]thymidine incorporation and DNA concentra

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Wai, Clifford Y., Mikio A. Nihira, Peter G. Drewes, Joe S. Chang, Momin T. Siddiqui, and David L. Hemsell. "Actinomyces Associated With Persistent Vaginal Granulation Tissue." Infectious Diseases in Obstetrics and Gynecology 13, no. 1 (2005): 53–55. http://dx.doi.org/10.1155/2005/252691.

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Background:We report a case of symptomatic actinomycosis associated with vaginal suture erosion and granulation tissue refractory to conservative management, in an outpatient setting.Case:Three months after total vaginal hysterectomy and uterosacral ligament vaginal vault suspension, a woman complained of painless, intermittent vaginal discharge and spotting. Despite cauterization of granulation tissue, vaginal spotting persisted for another month. On re-examination, braided polyester suture that was found underlying the granulation tissue was removed. Recurrent symptoms, together with a biops

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ZHANG, Jie, Ting WANG, Juan WANG, et al. "Effect of three interventional bronchoscopic methods on tracheal stenosis and the formation of granulation tissues in dogs." Chinese Medical Journal 123, no. 5 (2010): 621–27. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.2010.05.021.

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Background Therapeutic approaches for tracheal stenosis caused by the formation of exuberant granulation tissues usually include electrocautery, mechanical dilation, laser therapy, argon plasma coagulation (APC), cryotherapy and stent placement. However, restenosis after stent insertion remains a significant limitation. We examined the efficacy of three different approaches, including induction of mechanical lesions, APC performed with different powers or durations and cryotherapy, to identify the method that limited the formation of granulation tissue. Methods Twelve specially bred research m

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Rasheed, Razim Abdul, Mubeena ., and K. S. Gangadhara Somayaji. "Pre-operative predictors of ossicular necrosis in chronic otitis media-mucosal type." International Journal of Otorhinolaryngology and Head and Neck Surgery 5, no. 2 (2019): 396. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20190769.

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<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media can cause a wide range of pathologies in the middle ear that include irreversible mucosal changes, granulation tissue formation, cholesteatoma, tympanosclerosis, and destruction of ossicles. Knowledge regarding ossicular discontinuity before surgery enables the surgeon to be prepared for ossiculoplasty. Objective was to study the pre-operative clinical, audiological and microscopic findings in chronic otitis media mucosal type and correlate preoperative findings with intra-operative ossicular ne

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Tondok, Santalia Banne, Demianus Tafor, Sethiana Dewi Ruben, Wanuliana Wanuliana, and Nasrah Nasrah. "Utilization of Red Fruit on The Growth of Tissue Granulation in Diabetic Wounds." Jurnal Penelitian Pendidikan IPA 9, no. 11 (2023): 10186–90. http://dx.doi.org/10.29303/jppipa.v9i11.4677.

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The utilization of red fruit on the growth of granulation tissue in diabetic wounds aims to determine the benefits of red fruit which have been scientifically proven through research in Indonesia. Methods: Conducting a literature search using the Google Scholar application and conducting an analysis of the literature included in the inclusion criteria. Results: From the search results and research results which conclude about the benefits of red fruit. Conclusion: The benefits of red fruit on the growth of granulation tissue in diabetic wounds, namely red fruit contains carotene (12,000 ppm),

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Rioja, E., J.-L. Blanch, A. Borés, M. Bernal-Sprekelsen, and I. Vilaseca. "Clinical significance of granulation tissue after transoral laser microsurgery for glottic cancer." Journal of Laryngology & Otology 129, no. 4 (2015): 377–82. http://dx.doi.org/10.1017/s0022215115000444.

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AbstractBackground:Granulation tissue after transoral laser microsurgery can make it difficult to distinguish between normal healing and tumour recurrence.Materials and methods:We carried out a retrospective analysis of 316 consecutive glottic carcinomas (Tis–T3). Presence of granulation tissue at one and six months was correlated with demographic and clinical data, tumour and surgical characteristics, and tumour relapse.Results:Granulation tissue appeared in 53.8 per cent of patients at month 1, resolving spontaneously in 41.8 per cent. Revision surgery was performed in 60.1 per cent and was

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Iwanaga, Michitaka, Etsuo Yamamoto, and Manabu Fukumoto. "Cathepsin Activity in Cholesteatoma." Annals of Otology, Rhinology & Laryngology 94, no. 3 (1985): 309–12. http://dx.doi.org/10.1177/000348948509400318.

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Collagenolytic cathepsin, presumed to play an important role in bone destruction of cholesteatoma, was investigated in cholesteatoma epithelium, subepithelial granulation tissue, skin from the bony external auditory meatus and, temporal bone. The enzyme extracted from tissues was proven to be lysosomal cathepsin B by SDS gel electrophoresis in the use of human type I and type III collagen. α-N-benzoyl-DL-arginine-2-naphthylamide HC1 (BANA) was supposed to be specific for cathepsin B, and so BANA-hydrolase activity was measured as collagen-degrading cathepsin. The results showed that tissues ha

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Vagholkar, Ketan, Samriddhi Sharma, Subashchandra Subudhi, Deep Mashru, Annvi Shah, and Suvarna Vagholkar. "Combination therapy for recurrent ingrown toe nail." International Surgery Journal 4, no. 7 (2017): 2345. http://dx.doi.org/10.18203/2349-2902.isj20172619.

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Ingrown toe nail is one of the commonest foot lesion affecting young individuals. The recurrence rate with a variety of treatment modalities continues to be quite significant. Hence the need to develop a comprehensive combination therapy to reduce the recurrence rate. Onychocryptosis or ingrown toe nail is a common and painful form of nail disease. It affects adolescents and young males very commonly. A combination therapy comprising of wedge resection of the nail, matricectomy, phenol cauterization and wedge excision of hyper granulations for recurrent advanced presentation of ingrown toe nai

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Larjava, H., J. Heino, V. M. Kähäri, T. Krusius, and E. Vuorio. "Characterization of One Phenotype of Human Periodontal Granulation-tissue Fibroblasts." Journal of Dental Research 68, no. 1 (1989): 20–25. http://dx.doi.org/10.1177/00220345890680010301.

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Human granulation-tissue fibroblasts were cultured from oral chronic inflammatory lesions and compared with fibroblasts of healthy gingival connective tissue with respect to cell-surface sialoglycoproteins, and the synthesis of extracellular matrix components. Granulation-tissue fibroblasts exhibited a slower growth rate and larger size than their controls. Their cell-surface sialoglycoproteins resembled those of the control cells, except that the relative amount of glycoproteins in the 140-kd region was lower. The ratio of mRNAs for proαl(I) and proαl(III) collagen chains was decreased in gra

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SHIMIZU, Hiroki. "Anal Fistula with Inflammatory Granulation Tissue." Nishi Nihon Hifuka 82, no. 2 (2020): 73–74. http://dx.doi.org/10.2336/nishinihonhifu.82.73.

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Tan, Yongcheng Benjamin. "Myeloid Sarcoma Masquerading as Granulation Tissue." International Journal of Surgical Pathology 23, no. 7 (2015): 553–56. http://dx.doi.org/10.1177/1066896915588931.

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Carlson, Mark A., and Jon S. Thompson. "Wound splinting modulates granulation tissue proliferation." Matrix Biology 23, no. 4 (2004): 243–50. http://dx.doi.org/10.1016/j.matbio.2004.05.006.

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Puig, Lluis, Abelardo Moreno, Enric Llistosella, Xavier Noguera, and J. M. Moragas. "Granulation Tissue Proliferation During Isotretinoin Treatment." International Journal of Dermatology 25, no. 3 (1986): 191–95. http://dx.doi.org/10.1111/j.1365-4362.1986.tb02218.x.

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Carlson, Mark A., Michael T. Longaker, and Jon S. Thompson. "Wound splinting regulates granulation tissue survival." Journal of Surgical Research 110, no. 1 (2003): 304–9. http://dx.doi.org/10.1016/s0022-4804(02)00098-7.

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NORWOOD, O'TAR T. "Excessive Granulation Tissue after Hair Transplantation." Journal of Dermatologic Surgery and Oncology 11, no. 6 (1985): 566. http://dx.doi.org/10.1111/j.1524-4725.1985.tb01895.x.

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Sarkisov, D. S., E. G. Kolokol'chikova, R. I. Kaem, and A. A. Pal'tsyn. "Vascular changes in maturing granulation tissue." Bulletin of Experimental Biology and Medicine 105, no. 4 (1988): 604–7. http://dx.doi.org/10.1007/bf00841219.

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Hakkinen, L., and H. Larjava. "Characterization of Fibroblast Clones from Periodontal Granulation Tissue in vitro." Journal of Dental Research 71, no. 12 (1992): 1901–7. http://dx.doi.org/10.1177/00220345920710120901.

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Connective tissues are known to be composed of heterogeneous fibroblast subpopulations. The significance of this heterogeneity in different physiological and pathological conditions is poorly understood. Granulation tissue is formed in connective tissue during wound healing, chronic inflammation, and certain pathological conditions. In this study, heterogeneity of fibroblasts from granulation tissue was investigated by cell-cloning techniques. Granulation-tissue fibroblasts (GTFs) from both chronically inflamed periodontal lesions and healing wound granulation tissue behaved similarly. GTFs sh

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Morar, I. K., O. I. Ivashchuk, I. S. Davydenko, V. Yu Bodyaka, and Yu Ya Chuprovskaya. "Peculiarities of granulation tissue morphology around a netalotransplant in preoperative irrigation of the abdominal cavity." Experimental and Clinical Medicine 87, no. 2 (2020): 4–13. http://dx.doi.org/10.35339/ekm.2020.87.02.01.

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The experiment investigated the influence of preoperative remote gamma therapy on the features of the morphology of granulation tissue around the elements of the reticular allograft of the muscular-aponeurotic layer of the anterior abdominal wall. It is established that the use of preoperative remote gamma therapy distorts the maturation of granulation tissue. There is a probable increase in the percentage of fibroblasts and a decrease in lymphoid cells, polymorphonuclear leukocytes, macrophages, and plasma cells in the granulation tissue, mainly on the 5th and 7th day after surgery. Also on t

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Sato, Kayoko, Yasuyuki Imai, Nobuaki Higashi, et al. "Lack of antigen-specific tissue remodeling in mice deficient in the macrophage galactose-type calcium-type lectin 1/CD301a." Blood 106, no. 1 (2005): 207–15. http://dx.doi.org/10.1182/blood-2004-12-4943.

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Macrophage galactose-type C-type lectins (MGLs), which were recently named CD301, have 2 homologues in mice: MGL1 and MGL2. MGLs are expressed on macrophages and immature dendritic cells. The persistent presence of granulation tissue induced by a protein antigen was observed in wild-type mice but not in mice lacking an endogenous, macrophage-specific, galactose-type calcium-type lectin 1 (MGL1) in an air pouch model. The anti-MGL1 antibody suppressed the granulation tissue formation in wild-type mice. A large number of cells, present only in the pouch of MGL1-deficient mice, were not myeloid o

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Jimi, Shiro, Satoshi Takagi, Francesco De Francesco, Motoyasu Miyazaki, and Arman Saparov. "Acceleration of Skin Wound-Healing Reactions by Autologous Micrograft Tissue Suspension." Medicina 56, no. 7 (2020): 321. http://dx.doi.org/10.3390/medicina56070321.

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Background and objectives: Skin grafting is a method usually used in reconstructive surgery to accelerate skin regeneration. This method results frequently in unexpected scar formations. We previously showed that cutaneous wound-healing in normal mice is accelerated by a micrograft (MG) technique. Presently, clinical trials have been performed utilizing this technology; however, the driving mechanisms behind the beneficial effects of this approach remain unclear. In the present study, we focused on five major tissue reactions in wound-healing, namely, regeneration, migration, granulation, neov

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Komelyagina, Elena Yur'evna, Eugenia Alexandrovna Kogan, and Mikhail Borisovich Antsiferov. "Clinical and morphological characteristics of wound healing in diabetic foot syndrome." Diabetes mellitus 20, no. 2 (2017): 135–41. http://dx.doi.org/10.14341/7704.

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Aim. To assess the clinical and morphological characteristics of neuropathic diabetic foot ulcers (DFUn) Materials and Methods.Forty-three specimens of DFUn were analysed. Depending on the outcome, samples were divided into 2 groups: group 1healed ulcers (30 samples), group 2unhealed ulcers (13 samples). The following characteristics were analysed: age, sex, glycated haemoglobin (HbA1c), ulcer duration, time of admission to the specialised clinic, severity of neuropathy, presence of late complications, plantar localisation, percentage of necrotic tissue, granulation and fibrotic tissue a

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Tan, Naiwen, Maja Sabalic, Linh Nguyen, and Francesco D’Aiuto. "Regenerative Potential of Granulation Tissue in Periodontitis: A Systematic Review and Meta-analysis." Stem Cells International 2023 (March 7, 2023): 1–11. http://dx.doi.org/10.1155/2023/8789852.

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Background and Aim. Soft and hard periodontal tissues contain limited numbers of stem cells. This makes regeneration of the periodontium in patients with periodontitis challenging and unpredictable. Granulation tissue is traditionally removed during periodontal corrective therapy, but it is believed to contain multipotent stem cells which could be used for regenerative therapy. The aim of this research was to critically appraise the evidence on cellular components within granulation tissue in patients with periodontitis and its regenerative potential when compared to control healthy periodonta

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Parmar, Dr Kirit D., Dr Pratik H. Vyas, Dr Yajurvendra Gohil, Dr Jaydeep A. Maheshwari, Dr Dharmik B. Gondalia, and Dr Bhargav M. Vasiyani. "A Study of Vacuum Assisted Closure Dressing in 50 Cases of Patients of Diabetic Limb." BJKines National Journal of Basic & Applied Sciences 14, no. 1 (2022): 53–57. http://dx.doi.org/10.56018/bjkines2022068.

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Background: To evaluate the effectiveness of VAC dressing for the management of diabetic limb. Material and Method: The study is a prospective comparative study which was conducted on 50 patients of diabetic limb ulcers admitted in General Surgery Department at Tertiary care hospital between June 2017 to June 2019. Patients were followed up until discharged from the hospital or completion of 8 weeks assessment period from the date of admission whichever was earlier. Result: Ulcer due to diabetes is common in males. 4% of the patients had hba1c level between 6.5 to 9.5. In 64% of patients granu

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Steenfos, H. H., and J. O. Jansson. "Growth hormone stimulates granulation tissue formation and insulin-like growth factor-I gene expression in wound chambers in the rat." Journal of Endocrinology 132, no. 2 (1992): 293–98. http://dx.doi.org/10.1677/joe.0.1320293.

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ABSTRACT It has been reported that GH stimulates fibroblast growth and wound healing. In the present study we measured the effect of locally applied GH on insulin-like growth factor (IGF-I) mRNA concentrations and granulation tissue formation in wound cylinders, implanted s.c. Four stainless-steel wiremesh cylinders were implanted s.c. in the back of male rats (280 g). Each cylinder was then injected every day with either 0·014 or 0·14 U human GH, or vehicle only. Ingrown granulation tissue and wound fluid was obtained on day 17 after implantation. The wet weight of granulation tissue was dete

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Fortuna, Fory, Nandita Melati Putri, and Gentur Sudjatmiko. "Granulation Red Index To Assess Pressure Ulcer Granulation Tissue Quality Treated By Honey Gauze Dressing By Digital Image Analysis." Jurnal Plastik Rekonstruksi 6, no. 2 (2020): 270–75. http://dx.doi.org/10.14228/jpr.v6i2.284.

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Background : Good formation of granulation tissue in the ulcer bed is regarded as one of the indicators of pressure ulcer healing. Granulation red index (GRI) had been published as an objective parameter to assess the quality of granulation tissue. Honey stimulates granulation of tissue and creates a moist healing environment. However, the assessment of granulation tissue quality of pressure ulcers treated by honey has yet to be proven in clinical settings. In this study, we evaluate the granulation tissue quality of pressure ulcers treated by honey using granulation red index by digital image

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Aprile, I., S. Pizzolitto, F. De Nardi, et al. "Correlazione RM-istopatologica del potenziamento periferico delle ernie discali." Rivista di Neuroradiologia 10, no. 2_suppl (1997): 213–14. http://dx.doi.org/10.1177/19714009970100s295.

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We found ring enhancement in 10 patients with lumbar disc herniation examined with magnetic resonance. In 5 cases histological examination showed peri-discal granulation tissue. The peripheral enhancement found in some cases of disc herniation is caused by inflammatory granulation tissue.

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Ahmad, Samera, Daniel Capiz-Correa, and Hans E. Grossniklaus. "Pyogenic Granuloma of the Retina: A Case Series." Ocular Oncology and Pathology 5, no. 3 (2018): 176–81. http://dx.doi.org/10.1159/000492598.

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Aim: To describe the clinicopathologic features of pyogenic granuloma (granulation tissue proliferation) extending from the retina. Methods: We describe 3 patients who underwent enucleation for endophthalmitis. The eyes were processed routinely for histopathologic examination. Results: All 3 enucleated eyes contained granulation tissue with reactive vascular channels and intervening stroma infiltrated with inflammatory cells. The vascular channels were arranged in a fan-like configuration and the tissue was classified as representing pyogenic granulomas. Conclusions: Pyogenic granulomas (granu

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Krishnaprasad, I. N., V. Soumya, and S. Abdulgafoor. "Management of Over-Granulation in a Diabetic Foot Ulcer: A Clinical Experience." Indian Journal of Physical Medicine and Rehabilitation 24, no. 1 (2013): 19–22. http://dx.doi.org/10.5005/ijopmr-24-1-19.

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Abstract Over-granulation or exuberant granulation tissue is a common problem encountered in the care of chronic wounds, especially that of diabetic foot ulcers. There are several potential options for the treatment of this challenging problem. Some have an immediate short term effect but may have a longer term unfavourable effect, for example, silver nitrate application and surgical excision, which may delay wound healing by reverting the wound back to the inflammatory phase of healing. Other products, such as foams and silver dressings may offer some effect in short term, but their long term

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Shrestha, D., P. Thapa, and YB Bhandari. "Types of pathology and ossicular status in atticoantral disease undergoing mastoidectomy at Bir Hospital." Journal of College of Medical Sciences-Nepal 6, no. 4 (2012): 26–30. http://dx.doi.org/10.3126/jcmsn.v6i4.6722.

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A prospective study was carried out in the department of ENT and Head and Neck Surgery in Bir Hospital, Kathmandu to know the types of the pathology and the ossicular status in atticoantral disease. This study included 100 cases of CSOM (AA) scheduled for routine mastoidectomy. In this study cholesteotoma was the commonest pathology 61 (61%) followed by granulation tissue alone in 27 (27%) cases and both cholesteotoma and granulation tissue were found in 12 (12%) cases. Ossicular damage was more common in CSOM (AA) with granulation tissue in all 27 (100%), 54(58.06%) in CSOM(AA) with cholesteo

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