Academic literature on the topic 'Tissue hypo perfusion'

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Journal articles on the topic "Tissue hypo perfusion"

1

Reitmeir, Raluca, Jens Eyding, Markus F. Oertel, et al. "Is ultrasound perfusion imaging capable of detecting mismatch? A proof-of-concept study in acute stroke patients." Journal of Cerebral Blood Flow & Metabolism 37, no. 4 (2016): 1517–26. http://dx.doi.org/10.1177/0271678x16657574.

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In this study, we compared contrast-enhanced ultrasound perfusion imaging with magnetic resonance perfusion-weighted imaging or perfusion computed tomography for detecting normo-, hypo-, and nonperfused brain areas in acute middle cerebral artery stroke. We performed high mechanical index contrast-enhanced ultrasound perfusion imaging in 30 patients. Time-to-peak intensity of 10 ischemic regions of interests was compared to four standardized nonischemic regions of interests of the same patient. A time-to-peak >3 s (ultrasound perfusion imaging) or >4 s (perfusion computed tomography and
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2

Eyding, Jens, Christos Krogias, Martin Schöllhammer, et al. "Contrast-Enhanced Ultrasonic Parametric Perfusion Imaging Detects Dysfunctional Tissue at Risk in Acute MCA Stroke." Journal of Cerebral Blood Flow & Metabolism 26, no. 4 (2005): 576–82. http://dx.doi.org/10.1038/sj.jcbfm.9600216.

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Ultrasonic perfusion imaging predicts size and localization of acute stroke. It is unclear whether irreversibly damaged tissue can be differentiated from tissue at risk. Thirty-four patients (ischemic stroke <12 h) were included (Phase Inversion Harmonic Perfusion Imaging; bolus kinetic; fitted model function). Three patterns of perfusion were defined in 14 prespecified regions of interest (ROI): ‘normal', ‘hypoperfusion', and ‘no perfusion'. Clinical status was assessed using the National Institutes of Health Stroke Scale (NIHSS) (at baseline and at days 2 to 4). Cranial Computed Tomograph
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3

Skopalík, Josef, Jiří Sekora, Martin Pešl, et al. "UPGRADE OF THE LANGENDORFF APPARATUS USING THE INFRARED THERMO-CONTROL SYSTEM AND AN INTELLIGENT HEATER." Lékař a technika - Clinician and Technology 50, no. 4 (2020): 137–41. http://dx.doi.org/10.14311/ctj.2020.4.03.

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Biological experiments involving isolated organs and tissues demand precise temperature monitoring and regulation. An automatic temperature control system was proposed and optimised on real isolated swine hearts and the prototype is described in this work. The traditional Langendorff apparatus consists of a heart holder, a reservoir of perfusion solution flowing to aortic cannula and a heating bath allowing passive heat transfer to the reservoir of perfusion solution. The commercial infrared camera FLIR T62101 was added to this basic set-up and used for very precise monitoring of the temperatu
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4

International, Journal of Medical Science and Innovative Research (IJMSIR). "Association of serum lactate and morbidity in patients undergoing major abdominal surgery- A Literature Review." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 3 (2024): 22–29. https://doi.org/10.5281/zenodo.15402734.

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<strong>Abstract</strong> Major abdominal surgery carries a significant risk of postoperative morbidity and prolonged hospital stays. Timely identification of complications and appropriate management strategies are crucial for optimizing patient outcomes. Serum lactate levels have emerged as a potential biomarker for assessing tissue hypo perfusion and predicting adverse outcomes in various clinical settings. This research paper aims to review the existing literature on the utility of serum lactate as an indicator for morbidity and hospital stay in patients undergoing major abdominal surgery.
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5

Costa, Filipe Gonçalves, Naser Hakimi, and Frank Van Bel. "Neuroprotection of the Perinatal Brain by Early Information of Cerebral Oxygenation and Perfusion Patterns." International Journal of Molecular Sciences 22, no. 10 (2021): 5389. http://dx.doi.org/10.3390/ijms22105389.

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Abnormal patterns of cerebral perfusion/oxygenation are associated with neuronal damage. In preterm neonates, hypoxemia, hypo-/hypercapnia and lack of cerebral autoregulation are related to peri-intraventricular hemorrhages and white matter injury. Reperfusion damage after perinatal hypoxic ischemia in term neonates seems related with cerebral hyperoxygenation. Since biological tissue is transparent for near infrared (NIR) light, NIR-spectroscopy (NIRS) is a noninvasive bedside tool to monitor brain oxygenation and perfusion. This review focuses on early assessment and guiding abnormal cerebra
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Smith, M. L., R. von Hanwehr, and B. K. Siesjö. "Changes in Extra- and Intracellular pH in the Brain during and following Ischemia in Hyperglycemic and in Moderately Hypoglycemic Rats." Journal of Cerebral Blood Flow & Metabolism 6, no. 5 (1986): 574–83. http://dx.doi.org/10.1038/jcbfm.1986.104.

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Incomplete forebrain ischemia of 15-min duration was induced in rats made hyperglycemic or moderately hypoglycemic prior to ischemia. Tissue CO2 tension, CO2 content, labile tissue metabolites, and extracellular pH (pHe) were measured, and intracellular pH (pHi) was derived by calculation on the assumption that cerebral intracellular fluids can be lumped into one space. In hypoglycemic animals, mean tissue lactate content increased from 2 to 10 μmol g−1. Tissue CO2 content was virtually unchanged and the CO2 tension increased from ∼50 to ∼145 mm Hg. In hyperglycemic animals, tissue lactate con
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7

Eyding, Jens, Christian Fung, Wolf-Dirk Niesen, and Christos Krogias. "Twenty Years of Cerebral Ultrasound Perfusion Imaging—Is the Best yet to Come?" Journal of Clinical Medicine 9, no. 3 (2020): 816. http://dx.doi.org/10.3390/jcm9030816.

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Over the past 20 years, ultrasonic cerebral perfusion imaging (UPI) has been introduced and validated applying different data acquisition and processing approaches. Clinical data were collected mainly in acute stroke patients. Some efforts were undertaken in order to compare different technical settings and validate results to gold standard perfusion imaging. This review illustrates the evolution of the method, explicating different technical aspects and milestones achieved over time. Up to date, advancements of ultrasound technology as well as data processing approaches enable semi-quantitati
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8

Duelli, Roman, and Wolfgang Kuschinsky. "Changes in Brain Capillary Diameter during Hypocapnia and Hypercapnia." Journal of Cerebral Blood Flow & Metabolism 13, no. 6 (1993): 1025–28. http://dx.doi.org/10.1038/jcbfm.1993.129.

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Since changes in the surface area of capillaries may be relevant to capillary exchange, the distensibility of brain capillaries was investigated. Brain capillary diameters were measured after perfusion fixation of brain tissue at a constant perfusion pressure during hypo- or hypercapnia. Sections were embedded, stained, and analyzed by light microscopy. The results showed significant differences in mean capillary diameter between the hypocapnic and the hypercapnic group. In the eight brain structures analyzed, capillary diameters were always larger in the hypercapnic group. Mean capillary diam
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9

Thompson, Cynthia K., Matthew Walenski, YuFen Chen, et al. "Intrahemispheric Perfusion in Chronic Stroke-Induced Aphasia." Neural Plasticity 2017 (2017): 1–15. http://dx.doi.org/10.1155/2017/2361691.

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Stroke-induced alterations in cerebral blood flow (perfusion) may contribute to functional language impairments and recovery in chronic aphasia. Using MRI, we examined perfusion in the right and left hemispheres of 35 aphasic and 16 healthy control participants. Across 76 regions (38 per hemisphere), no significant between-subjects differences were found in the left, whereas blood flow in the right was increased in the aphasic compared to the control participants. Region-of-interest (ROI) analyses showed a varied pattern of hypo- and hyperperfused regions across hemispheres in the aphasic part
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Frustaci, Andrea, Rosario Cianci, Romina Verardo, Bruna Cerbelli, Maria Cecilia D’Asdia, and Alessandro De Luca. "Novel Genetic Microvascular Dysplasia Causing Hypoperfusion of Cardiac, Renal, and Cerebral Circulation." Journal of Clinical Medicine 12, no. 22 (2023): 7150. http://dx.doi.org/10.3390/jcm12227150.

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Background: Microvascular disorders represent an uncommon site of tissue hypo-perfusion and damage. Various genetic and acquired causes can be involved. A 65-year-old man was admitted because of refractory angina, which he had had since the age of 30 years, micro-hematuria, and recurrent transitory ischemic attacks from the age of 64. Methods: Hematochemical studies, ECG, Holter monitoring, 2D-echo, cardiac magnetic resonance (CMR), CTA of cerebral vessels, endomyocardial coronary angiography, and kidney biopsy processes were undertaken. Gene mutation analysis was conducted using next-generati
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