Academic literature on the topic 'Tissue specificity'

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Journal articles on the topic "Tissue specificity"

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Vinogradov, A. E. "Isochores and tissue-specificity." Nucleic Acids Research 31, no. 17 (2003): 5212–20. http://dx.doi.org/10.1093/nar/gkg699.

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Pei, Guangsheng, Yulin Dai, Zhongming Zhao, and Peilin Jia. "deTS: tissue-specific enrichment analysis to decode tissue specificity." Bioinformatics 35, no. 19 (2019): 3842–45. http://dx.doi.org/10.1093/bioinformatics/btz138.

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Abstract Motivation Diseases and traits are under dynamic tissue-specific regulation. However, heterogeneous tissues are often collected in biomedical studies, which reduce the power in the identification of disease-associated variants and gene expression profiles. Results We present deTS, an R package, to conduct tissue-specific enrichment analysis with two built-in reference panels. Statistical methods are developed and implemented for detecting tissue-specific genes and for enrichment test of different forms of query data. Our applications using multi-trait genome-wide association studies d
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Lundborg, Göran, Lars B. Dahlin, Nils Danielsen, and Ann K. Nachemson. "Tissue Specificity in Nerve Regeneration." Scandinavian Journal of Plastic and Reconstructive Surgery 20, no. 3 (1986): 279–83. http://dx.doi.org/10.3109/02844318609004486.

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Milgrom, Felix. "Tissue Specificity and Autoimmune Responses." Immunological Investigations 18, no. 1-4 (1989): xxxi—xliv. http://dx.doi.org/10.3109/08820138909112222.

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Rossignol, Rodrigue, Monique Malgat, Jean-Pierre Mazat, and Thierry Letellier. "Threshold Effect and Tissue Specificity." Journal of Biological Chemistry 274, no. 47 (1999): 33426–32. http://dx.doi.org/10.1074/jbc.274.47.33426.

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Alderton, Gemma. "Tissue specificity in cancer drivers." Science 363, no. 6432 (2019): 1187.14–1189. http://dx.doi.org/10.1126/science.363.6432.1187-n.

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Aguet, François, and Kristin G. Ardlie. "Tissue Specificity of Gene Expression." Current Genetic Medicine Reports 4, no. 4 (2016): 163–69. http://dx.doi.org/10.1007/s40142-016-0105-2.

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Funder, John W. "Target tissue specificity of mineralocorticoids." Trends in Endocrinology & Metabolism 1, no. 3 (1990): 145–48. http://dx.doi.org/10.1016/1043-2760(90)90026-y.

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de Graaf, D. C., and F. J. Jacobs. "Tissue specificity of Nosema apis." Journal of Invertebrate Pathology 58, no. 2 (1991): 277–78. http://dx.doi.org/10.1016/0022-2011(91)90073-y.

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Miyazaki, Jun-Ichi, Toshiki Makioka, Yoshihiro Fujiwara, and Tamio Hirabayashi. "Tissue specificity of crustacean tropomyosin." Journal of Experimental Zoology 263, no. 3 (1992): 235–44. http://dx.doi.org/10.1002/jez.1402630303.

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Dissertations / Theses on the topic "Tissue specificity"

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Mistry, Nitesh. "Human papillomavirus tropism : determinants of viral tissue specificity." Doctoral thesis, Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1149.

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Bartsakoulia, Marina. "Investigating the reversibility and tissue specificity of mitochondrial disorders." Thesis, University of Newcastle upon Tyne, 2017. http://hdl.handle.net/10443/3832.

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Mitochondrial disorders comprise a large group of heterogeneous disorders which are characterized by impairments in the cellular energy production. One of the great challenges of mitochondrial disease is the variety of clinical features present in patients. Mitochondrial disorders affect more than one organ leading to complex multisystem dysfunctions. Tissues, in which the metabolic demand is higher, such as skeletal muscle, neurons, liver or heart are typically affected. Mutations in both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) often lead to mitochondrial disorders. Although mtDNA en
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Dos, Santos Brilha Sara Sofia. "Tissue specificity of MMP gene expression and secretion in tuberculosis." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/51148.

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In tuberculosis (TB), matrix metalloproteinases (MMPs) have a major role in tissue destruction and cavitation. The composition of each extracellular matrix (ECM) gives specificity to tissues and is important in control of local immune responses by acting as a “molecular postcode”. Hence, it is likely to have important implications in TB. During central nervous system (CNS) infection, the effect of TB on blood-brain barrier (BBB) function is unknown. I hypothesised that the ECM environment may determine the MMP response during innate immune activation in pulmonary and CNS TB. I aimed to investi
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Ayala, Fierro Felix. "Tissue specificity for metabolism and toxicity of arsine and arsenite." Diss., The University of Arizona, 1999. http://hdl.handle.net/10150/284050.

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Accidental exposure to arsine (AsH₃) is possible in the semiconductor industry, metal mining, painting and herbicide preparation. First symptoms include intravascular hemolysis and dark red urine (hematuria), followed by abdominal pain, jaundice, and anemia. Exposure to AsH₃ is fatal in up to 25% of the reported human cases, usually caused by acute oliguric renal failure. The mechanism of AsH₃ toxicity in the kidney is unknown and was studied in vitro using established cell lines, primary cells, and isolated kidney. The hypothesis was that AsH₃ cause renal toxicity by its conversion to arsenit
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PELLEGRINI, Davide. "Development of high sensitivity and high specificity strategies for tissue microproteomics." Doctoral thesis, Scuola Normale Superiore, 2021. http://hdl.handle.net/11384/105431.

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Mass-spectrometry based proteomics has become an indispensable tool for molecular biology and clinical research because of its ability to identify and quantify thousands of proteins. When combined with laser capture microdissection (LCM), MS-based proteomics may be used to investigate disease-associated changes in the proteome of specific tissue regions or cell populations. Such specificity is essential because different anatomical regions often have distinct and diverse functions and may behave differently under pathological conditions. However, the number of proteins that may be identified a
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Yang, Rick L. "Tissue specificity of signal transmission and differential growth during maize root gravitropism." Connect to resource, 1992. http://rave.ohiolink.edu/etdc/view.cgi?acc%5Fnum=osu1244222463.

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Jia, Yizhen, and 贾亦真. "Bioinformatics study of the lineage and tissue specificity of genes and gene expression." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45540652.

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Freeman, Alistair Iain. "5' variants of glucocorticoid receptor mRNA : further studies of tissue-specificity and regulation." Thesis, University of Edinburgh, 2003. http://hdl.handle.net/1842/24590.

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Glucocorticoids have diverse physiological functions: they affect central nervous system function, intermediary metabolism and restore homeostasis after stress. Secretion of glucocorticoids is regulated by the hypothalamic-pituitary-adrenal (HPA) axis; negative feedback at the hypothalamus and pituitary suppresses glucocorticoid secretion while the hippocampus exerts additional control over HPA axis activity. Glucocorticoids exert most of their actions, including negative feedback, via the glucocorticoid receptor (GR). The glucocorticoid sensitivity of a given cell/tissue is dependent on the l
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Wieser, Daniela. "Exploiting gene expression and protein data for predicting remote homology and tissue specificity." Thesis, University of Southampton, 2010. https://eprints.soton.ac.uk/159177/.

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In this thesis I describe my investigations of applying machine learning methods to high throughput experimental and predicted biological data. The importance of such analysis as a means of making inferences about biological functions is widely acknowledged in the bioinformatics community. Specifically, this work makes three novel contributions based on the systematic analysis of publicly archived data of protein sequences, three dimensional structures, gene expression and functional annotations: (a) remote homology detection based on amino acid sequences and secondary structures; (b) the anal
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Youngman, Kenneth R. "Mechanisms of regulation of polymeric immunoglobulin receptor expression: Cytokine induction and tissue specificity." Case Western Reserve University School of Graduate Studies / OhioLINK, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=case1057587491.

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Books on the topic "Tissue specificity"

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Yang, Young Joo. The autophagosomal perspective: Tissue-specificity and cell-specificity of the autophagic response to starvation in vivo. [publisher not identified], 2020.

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Löfberg, Boël. Tissue specificity of N-nitrosamine metabolism: Studies in pregnant and non-pregnant rodents. Almqvist [och] Wiksell in Komm., 1985.

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Shulman, S. Tissue Specificity and Autoimmunity. Springer, 2011.

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The tissue-specificity of lymphocyte migration into inflamed tissues: A comparative study of synovium, skin and bowel. National Library of Canada = Bibliothèque nationale du Canada, 1991.

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Petzold, Axel. Tissue Biomarkers and Neuroprotection. Edited by David L. Reich, Stephan Mayer, and Suzan Uysal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190280253.003.0004.

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This chapter reviews the evidence for using biomarkers to measure damage to the central nervous system (CNS) in neurocritical care and perioperative medicine. A conceptual framework is provided to guide the optimal timing of blood, cerebrospinal fluid, and structural imaging biomarker assessment in relation to the onset of injury. A selection of well-validated, cell type–specific biomarkers of CNS tissue damage are reviewed, including their composition, biokinetics, and specificity for neurons, axons, astrocytes, and microglia. Each of these biomarkers will be reviewed in the pertinent clinica
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Sprouse, Adrienne. Toxins (DRAFT). Edited by Madeleine M. Castellanos. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190225889.003.0010.

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This chapter describes the categories of 300+ environmental chemicals measured in the blood and urine of Americans by the US Centers for Disease Control and Prevention. Some are endocrine-disrupting chemicals (EDCs) and substitute for endogenous hormones in a variety of metabolic processes affecting sexual health, obesity, diabetes, and behavior. The Monotonic Dose-Response (linear dose-response) is inappropriate when evaluating the health consequences of EDCs. Nonmonotonic Dose-Response Curves are better for considering the affinity of the ligand for the receptor, receptor saturation, ligand
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Kasprzak, Jaroslaw D., Anita Sadeghpour, and Ruxandra Jurcut. Doppler echocardiography. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0003.

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Doppler examination is an integral part of the echocardiogram. Current systems are equipped with spectral Doppler in continuous wave mode (offering measurements of high velocities with limited spatial specificity due to integration of signal along the scan line), pulsed wave mode (high spatial specificity with maximal recordable velocity reduced by the Nyquist limit), and colour Doppler flow mapping (allowing rapid identification of flow pattern within a cross-sectional B-mode sector). Tissue Doppler echocardiography emerged as a basic tool for sampling regional myocardial velocities, in pulse
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Freifeld, Alison G. An Introduction. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199938568.003.0100.

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This chapter focuses on solid tumors and how they can be treated. Solid tumors, lymphomas, and leukemias represent a widely diverse array of cancers. Until recently, the general approach to treating all of them was to administer cytotoxic anticancer drugs that damage proliferating cells by interfering with mitosis and other essential steps in cellular replication. Localized solid tumors are largely treated by surgical resection and radiotherapy, with cytotoxic chemotherapy being commonly used adjunctively or in cases of metastatic disease. A major drawback of this approach has been the lack of
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Yilmaz, Ali, and Anca Florian. Myocarditis: imaging techniques. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0367.

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The clinical presentation of myocarditis is multifaceted and electrocardiogram (ECG) changes as well as biomarkers tend to be non-specific. Therefore, the diagnosis of myocarditis can be challenging and should be based on an integrated approach including patient history, physical examination, non-invasive tests such as ECG and serum biomarkers, and non-invasive cardiac imaging. As myocarditis may lead to global ventricular dysfunction, regional wall motion abnormalities, and/or diastolic dysfunction, echocardiography should be routinely performed. However, hallmarks of acute myocarditis compri
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Hayashi, Daichi, Ali Guermazi, and Frank W. Roemer. Radiography and computed tomography imaging of osteoarthritis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0016.

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Osteoarthritis (OA) is the most prevalent joint disorder in the elderly worldwide and there is still no effective treatment, other than joint arthroplasty for end-stage OA, despite ongoing research efforts. Imaging is essential for assessing structural joint damage and disease progression. Radiography is the most widely used first-line imaging modality for structural OA evaluation. Its inherent limitations should be noted including lack of ability to directly visualize most OA-related pathological features in and around the joint, lack of sensitivity to longitudinal change and missing specific
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Book chapters on the topic "Tissue specificity"

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Fameli, Nicola, A. Mark Evans, and Cornelis van Breemen. "Tissue Specificity." In Store-operated Ca2+ entry (SOCE) pathways. Springer Vienna, 2011. http://dx.doi.org/10.1007/978-3-7091-0962-5_16.

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Blatter, Lothar A. "Tissue Specificity." In Store-operated Ca2+ entry (SOCE) pathways. Springer Vienna, 2011. http://dx.doi.org/10.1007/978-3-7091-0962-5_17.

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Stone, T. W., and H. A. Simmonds. "Tissue specificity of purine metabolism." In Purines: Basic and Clinical Aspects. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3911-3_3.

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Orfanos, Stylianos E., Linhua Zou, and John D. Catravas. "Pharmacodynamics, tissue-specificity of ACE inhibitors." In ACE Inhibitors. Birkhäuser Basel, 2001. http://dx.doi.org/10.1007/978-3-0348-7579-0_12.

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Zipori, Dov. "Stem Cells with No Tissue Specificity." In Biology of Stem Cells and the Molecular Basis of the Stem State. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-130-1_3.

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Phinney, B. O., C. R. Spray, Y. Suzuki, and P. Gaskin. "Gibberellin Metabolism in Maize: Tissue Specificity." In Gibberellins. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-3002-1_3.

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Freitas, Maria João, Daniela Patrício, and Margarida Fardilha. "Sperm Signaling Specificity: From Sperm Maturation to Oocyte Recognition." In Tissue-Specific Cell Signaling. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44436-5_9.

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Madison, Edwin L. "Substrate Specificity of Tissue Type Plasminogen Activator." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5391-5_11.

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Botelho, Lynne H. Parker, Christina Cade, Penny E. Phillips, and Gabor M. Rubanyi. "Tissue Specificity of Endothelin Synthesis and Binding." In Endothelin. Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4614-7514-9_6.

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Ryan, Clarence A. "Proteinase Inhibitor Gene Families: Tissue Specificity and Regulation." In Plant Gene Research. Springer Vienna, 1988. http://dx.doi.org/10.1007/978-3-7091-6950-6_12.

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Conference papers on the topic "Tissue specificity"

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Gkouzionis, Ioannis, Maxime Giot, Scarlet Nazarian, et al. "Classification of Gastrointestinal Tissue In Vivo During Upper GI Cancer Surgery Using Diffuse Reflectance Spectroscopy." In Clinical and Translational Biophotonics. Optica Publishing Group, 2025. https://doi.org/10.1364/translational.2025.tm3f.3.

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Cancers of the upper GI tract remain a major challenge. This preliminary in vivo analysis using diffuse reflectance spectroscopy demonstrated promising tissue discrimination accuracy during surgery (sensitivity: 77.36%, specificity: 95.14% for stomach; sensitivity: 85.24%, specificity: 81.47% for oesophagus), highlighting its potential to enhance surgical decision-making.
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de Wit, Jos, Sebastian Tonn, Mon-Ray Shao, Guido Van den Ackerveken, and Jeroen Kalkman. "3D visualization of plant-pathogen interaction inside plant leaves with dynamic contrast optical coherence tomography." In 3D Image Acquisition and Display: Technology, Perception and Applications. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/3d.2024.jth2a.16.

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Optical coherence tomography (OCT) can image deep inside scattering plant tissue with micrometer resolution. However, conventional OCT lacks specificity to distinguish plant tissue from pathogen tissue. Here we show how dynamic OCT (dOCT) creates functional contrast of Bremia, a downy mildew in lettuce, based on sub-resolution dynamic activity inside the tissue. We demonstrate its applicability for disease resistance quantification and longitudinal study of pathogen growth.
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Wei, Mian, and Wei Min. "Single-particle imaging of nanomedicine crossing the blood-brain barrier." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.om5e.1.

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Current understanding of nanocarrier-brain interaction remains elusive. Based on stimulated Raman scattering, we develop an optical method for imaging nanocarriers in brain tissue with single-particle sensitivity, chemical specificity, and particle counting capability.
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Nicolson, Fay, Bohdan Andreiuk, Eunah Lee, et al. "Optimization of Surface-Enhanced Spatially Offset Raman spectroscopy for Applications in Pre-Clinical Cancer Imaging." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.om3e.3.

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Achieving high selectivity and specificity in deep tumor imaging remains a critical challenge in optical imaging. While Raman spectroscopy has been widely used for imaging various tissues, its penetration depth in vivo is limited. Here, we introduce a novel approach that integrates Spatially Offset Raman Spectroscopy (SORS) with Surface Enhanced Raman Scattering (SERS) nanoparticles, known as Surface Enhanced Spatially Offset Raman Spectroscopy (SESORS), for in vivo imaging of deep-seated tumors. We detail the optimization of SORS instrumentation to improve signal-to-noise ratio (SNR), spectra
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Qin, Wei. "Analysis of tissue specificity of alternative polyadenylation sites." In ACAI 2022: 2022 5th International Conference on Algorithms, Computing and Artificial Intelligence. ACM, 2022. http://dx.doi.org/10.1145/3579654.3579722.

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Majumder, S. K., A. Uppal, and P. K. Gupta. "Nitrogen Laser Excited Autofluorescence Spectroscopy for Discrimination of Human Breast Malignancy." In Biomedical Optical Spectroscopy and Diagnostics. Optica Publishing Group, 2006. http://dx.doi.org/10.1364/bosd.1996.ft3.

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The results of our in-vitro studies on N2 laser excited autofluorescence from pathologically characterized cancerous and adjoining normal human breast tissues obtained after resection from 15 patients with breast cancer are presented. A 6-variable multivariate linear regression (MVLR) analysis used for maximizing discrimination between tissue types resulted in a sensitivity of 85.5% and a specificity of 87.07% towards cancer for unpaired comparison and a sensitivity of 93.1% and specificity of 87.1% for paired comparison of the tissue spectra.
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Khurtina, S. N., V. P. Voronin, A. M. Orlov, and S. A. Murzina. "TISSUE SPECIFICITY OF THE LIPID CONTENT OF THE ENDEMIC FISH SPECIES ANTARCTIC SILVERFISH PLEURAGRAMMA ANTARCTICUM." In NOVEL TECHNOLOGIES IN MEDICINE, BIOLOGY, PHARMACOLOGY AND ECOLOGY. LLC Institute Information Technologies, 2023. http://dx.doi.org/10.47501/978-5-6044060-3-8.137-142.

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The paper presents data on the lipid content of certain organs and tissues of Pleuragramma antarcticum from the Antarctic Strait (Atlantic sector of Antarctica). The obtained results on the tissue specificity of lipids and biochemical adaptations at the lipid level in this fish spe-cies, which contribute to the tolerance of the organism to influence of the extreme environ-mental factors of Antarctic ecosystems, are discussed.
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Wang, Yan. "Tissue and Drug Specificity of Drug Sensitivities in Different Cancer Cell Lines." In ICCBB '21: 2021 5th International Conference on Computational Biology and Bioinformatics. ACM, 2021. http://dx.doi.org/10.1145/3512452.3512462.

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Stepp, Herbert, and Alexander Hohla. "Clinical results with UV-excited autofluorescence spectroscopy in different organs." In European Conference on Biomedical Optics. Optica Publishing Group, 2001. http://dx.doi.org/10.1364/ecbo.2001.4432_221.

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UV-excitation with 308 nm was applied clinically to normal and diseased tissues from the urinary bladder, the brain and the lungs. With a multifiber catheter, fluorescence spectra were recorded and evaluated using the most significant wavelength ratios. Correlation with histology showed the following sensitivities / specificities for the detection of malignant tissue: bladder 90% / 81%, brain 62% / 100%, lungs 80% / 76%. Compared to 5-ALA induced PPIX-fluorescence (bladder), a higher specificity was observed. The results obtained intraoperatively were compared with UV-imaging and spectroscopy
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Moore, Amanda R., Jason Liang, Robert Piskol, Lisa McGinnis, Donald S. Kirkpatrick, and Shiva Malek. "Abstract 2923:RAS-mutant mouse models confirm tissue-specificity and reveal unique oncogenic activity of KrasQ61R." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-2923.

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Reports on the topic "Tissue specificity"

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Shani, Moshe, and C. P. Emerson. Genetic Manipulation of the Adipose Tissue via Transgenesis. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604929.bard.

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The long term goal of this study was to reduce caloric and fat content of beef and other red meats by means of genetic modification of the animal such that fat would not be accumulated. This was attempted by introducing into the germ line myogenic regulatory genes that would convert fat tissue to skeletal muscle. We first determined the consequences of ectopic expression of the myogenic regulatory gene MyoD1. It was found that deregulation of MyoD1 did not result in ectopic skeletal muscle formation but rather led to embryonic lethalities, probably due to its role in the control of the cell cy
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WANG, MIN, Sheng Chen, Changqing Zhong, et al. Diagnosis using artificial intelligence based on the endocytoscopic observation of the gastrointestinal tumours: a systematic review and meta-analysis. InPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.2.0096.

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Review question / Objective: With the development of endoscopic techniques, several diagnostic endoscopy methods are available for the diagnosis of malignant lesions, including magnified pigmented endoscopy and narrow band imaging (NBI).The main goal of endoscopy is to achieve the real-time diagnostic evaluation of the tissue, allowing an accurate assessment comparable to histopathological diagnosis based on structural and cellular heterogeneity to significantly improve the diagnostic rate for cancerous tissues. Endocytoscopy (ECS) is based on ultrahigh magnification endoscopy and has been app
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Levy, Avraham A., and Virginia Walbot. Regulation of Transposable Element Activities during Plant Development. United States Department of Agriculture, 1992. http://dx.doi.org/10.32747/1992.7568091.bard.

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We have studied the regulation of the maize Ac and MuDR transposable elements activities during plant development. Ac was studied in an heterologous system (transgenic tobacco plants and cell suspensions) while MuDR was studied in the native maize background. The focus of this study was on the transcriptional regulation of Ac and MuDR. For Ac, the major achievements were to show that 1-It is autoregulated in a way that the Ac-encoded transposase can repress the activity of its own promoter; 2-It is expressed at low basal level in all the plant organs that were studied, and its activity is stro
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Rafaeli, Ada, Russell Jurenka, and Chris Sander. Molecular characterisation of PBAN-receptors: a basis for the development and screening of antagonists against Pheromone biosynthesis in moth pest species. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7695862.bard.

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The original objectives of the approved proposal included: (a) The determination of species- and tissue-specificity of the PBAN-R; (b) the elucidation of the role of juvenile hormone in gene regulation of the PBAN-R; (c) the identificationof the ligand binding domains in the PBAN-R and (d) the development of efficient screening assays in order to screen potential antagonists that will block the PBAN-R. Background to the topic: Moths constitute one of the major groups of pest insects in agriculture and their reproductive behavior is dependent on chemical communication. Sex-pheromone blends are
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Elizur, Abigail, Amir Sagi, Gideon Hulata, Clive Jones, and Wayne Knibb. Improving Crustacean Aquaculture Production Efficiencies through Development of Monosex Populations Using Endocrine and Molecular Manipulations. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7613890.bard.

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Background Most of Australian prawn aquaculture production is based on P. monodon. However, the Australian industry is under intense competition from lower priced overseas imports. The availability of all-female monosex populations, by virtue of their large size and associated premium prize, will offer competitive advantage to the industry which desperately needs to counteract competitors within this market. As for the redclaw production in Israel, although it is at its infancy, the growers realized that the production of males is extremely advantageous and that such management strategy will c
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Freeman, Stanley, and Daniel Legard. Epidemiology and Etiology of Colletotrichum Species Causing Strawberry Diseases. United States Department of Agriculture, 2001. http://dx.doi.org/10.32747/2001.7695845.bard.

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Diseases caused by Colletotrichum spp. are one of the most important limitations on international strawberry production, affecting all vegetative and fruiting parts of the plant. From 1995 to 1997, C. acutatum infections reached epidemic levels in Israeli strawberry nurseries, causing extensive loss of transplants in fruit-bearing fields and additional reductions in yield. Although C. acutatum also occurs on strawberry in Florida, recent crown rot epidemics have been primarily caused by C. gloeosporioides. Little is known about the basic epidemiology of these important diseases on strawberry.
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Savaldi-Goldstein, Sigal, and Todd C. Mockler. Precise Mapping of Growth Hormone Effects by Cell-Specific Gene Activation Response. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7699849.bard.

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Plant yield largely depends on a complex interplay and feedback mechanisms of distinct hormonal pathways. Over the past decade great progress has been made in elucidating the global molecular mechanisms by which each hormone is produced and perceived. However, our knowledge of how interactions between hormonal pathways are spatially and temporally regulated remains rudimentary. For example, we have demonstrated that although the BR receptor BRI1 is widely expressed, the perception of BRs in epidermal cells is sufficient to control whole-organ growth. Supported by additional recent works, it is
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8

Friedmann, Michael, Charles J. Arntzen, and Hugh S. Mason. Expression of ETEC Enterotoxin in Tomato Fruit and Development of a Prototype Transgenic Tomato for Dissemination as an Oral Vaccine in Developing Countries. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7585203.bard.

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The broad objective of the project was to develop a feasible approach to combat diarrheal disease caused by ETEC through the development of a low-cost oral immunogen in tomato fruit, expressed in the context of a prototype tomato that would answer the shortcomings of plant oral vaccines, especially in terms of produce handling and control of gene escape. Specifically, the goals for Boyce Thompson Institute (BTI) on this project were to develop transgenic tomato lines that express the enterotoxigenic E. coli (ETEC) heat-labile enterotoxin (LT) subunits A and/or B for use in oral edible vaccines
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