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Dissertations / Theses on the topic 'Tissues'

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1

Moreau, Jodie E. "Stimulation of bone marrow stromal cells in the development of tissue engineered ligaments /." Thesis, Connect to Dissertations & Theses @ Tufts University, 2005.

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Thesis (Ph.D.)--Tufts University, 2005.<br>Adviser: Gregory H. Altman. Submitted to the Dept. of Biology--Biotechnology. Includes bibliographical references (leaves 183-192). Access restricted to members of the Tufts University community. Also available via the World Wide Web;
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2

Deiuliis, Jeffrey Alan. "The metabolic and molecular regulation of adipose triglyceride lipase." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1185546165.

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3

Craddock, Russell. "Structural characterisation of aggrecan in cartilaginous tissues and tissue engineered constructs." Thesis, University of Manchester, 2018. https://www.research.manchester.ac.uk/portal/en/theses/structural-characterisation-of-aggrecan-in-cartilaginous-tissues-and-tissue-engineered-constructs(d1e72d1e-b0ac-4485-9a05-030a5faf8351).html.

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Collagen II and the proteoglycan aggrecan are key extracellular matrix (ECM) proteins in cartilaginous tissues such as the intervertebral disc (IVD). Given the functional role that these structural and functional proteins have in the IVD, ECM in tissue engineered intervertebral disc (TE IVD) constructs needs to recapitulate native tissue. As such, there is a need to understand the structure and mechanical function of these molecules in native tissue to inform TE strategies. The aims here were to characterise aggrecan and collagen II using atomic force microscopy (AFM), size-exclusion chromatog
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4

Li, Zhaohui. "Monitoring biological functions of cultured tissues using microdialysis." Thesis, University of Oxford, 2007. http://ora.ox.ac.uk/objects/uuid:f8b478fa-881e-4299-9ee5-b8ee29f37fe9.

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Continuous monitoring during tissue culture is important for the success of engineered tissue development. It is also challenging due to lack of suitable established monitoring techniques. In this study, microdialysis, a sampling technique for measuring the unbound solute concentrations in the tissues and organs of the living body, was adopted to monitor functional tissue growth in a bioreactor with explanted bovine caudal intervertebral discs (IVD) as the test tissue. Apart from cell metabolic activities, cell and tissue biological functions were investigated for the development of microdialy
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5

Kalcioglu, Zeynep Ilke. "Mechanical behavior of tissue simulants and soft tissues under extreme loading conditions." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/79558.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 157-168).<br>Recent developments in computer-integrated surgery and in tissue-engineered constructs necessitate advances in experimental and analytical techniques in characterizing properties of mechanically compliant materials such as gels and soft tissues, particularly for small sample volumes. One goal of such developments is to quantitatively predict and mimic tissue deformation due to high rate impact
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Carlson, Grady E. "Dynamic Biochemical Tissue Analysis of L-selectin Ligands on Colon Cancer Tissues." Ohio University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1343932605.

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7

Ueda, Yuichiro. "Application of Tissue Engineering with Xenogenic Cells and Tissues for Regenerative Medicine." 京都大学 (Kyoto University), 2004. http://hdl.handle.net/2433/147657.

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8

Merkel, Matthias. "From cells to tissues." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-156597.

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An essential prerequisite for the existence of multi-cellular life is the organization of cells into tissues. In this thesis, we theoretically study how large-scale tissue properties can emerge from the collective behavior of individual cells. To this end, we focus on the properties of epithelial tissue, which is one of the major tissue types in animals. We study how rheological properties of epithelia emerge from cellular processes, and we develop a physical description for the dynamics of an epithelial cell polarity. We apply our theoretical studies to observations in the developing wing of
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9

Musson, David. "Adrenomedullin in dental tissues." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/794/.

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Tooth development is complex and dependent on epithelial-mesenchymal interactions involving key molecular signalling pathways. Preliminary data indicate that the pleiotropic growth factor adrenomedullin (ADM) is expressed during tooth development. Furthermore, in osteoblasts, cells which share structural and functional similarities to odontoblasts, ADM increases proliferation in vitro and can promote mineralised bone volume and strength in vivo. Immunohistochemical analysis of ADM demonstrated expression during key stages in tooth development in particular in cells responsible for signalling o
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10

Rosahl, Agnes Lioba. "How tissues tell time." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2015. http://dx.doi.org/10.18452/17113.

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Durch ihren Einfluß auf die Genexpression reguliert die zirkadiane Uhr physiologische Funktionen vieler Organe. Obwohl der zugrundeliegende allgemeine Uhrmechanismus gut untersucht ist, bestehen noch viele Unklarheiten über die gewebespezifische Regulation zirkadianer Gene. Neben ihrer gemeinsamen 24-h-Periode im Expressionsmuster unterscheiden diese sich darin, zu welcher Tageszeit sie am höchsten exprimiert sind und in welchem Gewebe sie oszillieren. Mittels Überrepräsentationsanalyse lassen sich Bindungsstellen von Transkriptionsfaktoren identifizieren, die an der Regulation ähnlich exprim
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11

Cristea, Anca. "Ultrasound tissue characterization using speckle statistics." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10329.

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L'objectif de la caractérisation des tissus par ultrasons ou ‘Quantitative Ultrasound (QUS)’ est de différencier les tissus pathologiques en associant les paramètres d’un modèle aux caractéristiques physiques du tissu. L'usage exclusif des ultrasons pour obtenir un diagnostic peut garantir que le patient ne subira pas une procédure invasive (e.g. une biopsie), utilisant des rayonnements ionisants (e.g. la tomographie) ou même inconfortable et coûteuse (e.g. IRM). Les méthodes de QUS extraient des informations sur la microstructure du tissu à partir du contenu spectral ou temporel des signaux u
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12

Lipworth, Wendy. "Reconfiguring tissue banking consent through enrichment of a restricted debate." Connect to full text, 2005. http://hdl.handle.net/2123/683.

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Thesis (M. Sc.)--University of Sydney, 2005.<br>Title from title screen (viewed 21 May 2008). Submitted in fulfilment of the requirements for the degree of Master of Science to the Unit for the History and Philosophy of Science and Centre for Values, Ethics and Law in Medicine. Includes bibliographical references. Also available in print form.
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13

Wijanto, Florent. "Multiscale mechanics of soft tissues." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLX093.

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Les réseaux de fibre sont une structure omniprésente dans les tissus biologiques, aussi bien au niveau macroscopique, où ils sont l'ingrédient principal des tissus mous, qu'au niveau microscopique, en tant que constituants des structures collagèniques ou du cytosquelette. L'objectif de ce travail de thèse est de proposer un modèle basé sur la microstructure physique des réseaux de fibres afin d'obtenir une compréhension du comportement mécanique des réseaux de fibres biologiques. Le modèle est basé sur une description de fibres glissant les unes par rapport aux autres et interagissant via des
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14

Yuan, Tai-Yi. "Innovative Methods to Determine Material Properties of Cartilaginous Tissues and Application for Tissue Engineering." Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_dissertations/607.

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Low back pain is one of the major health concerns in the US. It affects up to 80% of the population at some time during their lives. It not only causes discomfort to patients and affects their physical ability but also has a huge economic impact on society. Although the cause of low back pain is still poorly understood, it is implicated that degeneration of the intervertebral disc is the primary factor. Currently, researchers are trying to use tissue engineering approaches to develop new treatments capable of removing the degenerated disk and replacing it with a biological substitute. However
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15

Ralfs, Julie D. "The influence of freezing and tissue porosity on the material properties of vegetable tissues." Thesis, University of Reading, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251279.

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16

Swain, Robin. "Non-invasive biochemical analysis of cells, tissues and tissue constructs with Raman micro-spectroscopy." Thesis, Imperial College London, 2008. http://hdl.handle.net/10044/1/11327.

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17

Bittig, Thomas. "Morphogenetic signaling in growing tissues." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2008. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1222339699038-97723.

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During the development of multicellular organisms, organs grow to well-defined shapes and sizes. The proper size and patterning of tissues are ensured by signaling molecules as e.g. morphogens. Secreted from a restricted source, morphogens spread into the adjacent target tissue where they form a graded concentration profile. Upon binding of the morphogens to receptors on the cell surfaces, the morphogenetic signal is transduced inside the cell via the phosphorylation of transcription factors, which subsequently regulate the expression of different target genes. Thus, cell fates are determined
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18

Lee, Douglas P. "Glycerolipid metabolism in mammalian tissues." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2002. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ62649.pdf.

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19

Jang, Lee Jihye. "Glycomic analysis of biological tissues." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441384.

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20

Movasaghi, Zanyar. "Spectroscopic Investigation of Cancerous Tissues." Thesis, Queen Mary, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509600.

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21

Lawrence, C. E. "The regeneration of articular tissues." Thesis, Anglia Ruskin University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380722.

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Changes in the structural organization of cartilage and synovial tissue, or in the macromolecules produced by their cells, alter the properties of the tissues. Elucidation of the changes under controlled experimental conditions could make a significant contribution to the understanding of the pathogenesis of arthritis. To this end a model system has been developed to study proteoglycan and collagen regeneration in porcine articular cartilage and synovial tissue: partially depleted of matrix by exogenous enzyme(s), the tissues were maintained in organ culture, the medium consisting of Dulbecco'
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22

Bromley, M. "Histochemical studies in rheumatoid tissues." Thesis, University of Manchester, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370401.

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23

Farzaneh, Ali. "Computational morphogenesis of city tissues." Thesis, Open University, 2017. http://oro.open.ac.uk/49302/.

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Scientific discoveries of the 20th century had a profound impact not only on the study of the natural sciences but disciplines worldwide. The studies were rooted in understanding the complex process of organisation, development and evolution in natural systems before attempting to emulate the behaviours in artificial systems, leading to the emergence of new disciplines such as systems theory, complexity science, genetics, developmental and evolutionary biology. The discoveries had a profound impact in understanding the nature of cities as they develop over time. Once considered top-down models
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24

Dudko, Olga K., and George H. Weiss. "Photon diffusion in biological tissues." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-196826.

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The use of laser-based optical techniques for medical imaging is an attractive alternative to other methods that utilize ionizing radiation. Beside being non-carcinogenic, it is non-invasive, the equipment is transportable, and the methodology can be used to examine properties of soft tissue. However, unlike x-ray photons, optical photons generated in the near-infrared suffer significant amounts of scattering by heterogeneous bodies (e.g., organelles) found in biological tissue. Thus, theory is required to interpret experimental data which appear in the form o spatially or temporally varying l
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Dudko, Olga K., and George H. Weiss. "Photon diffusion in biological tissues." Diffusion fundamentals 2 (2005) 114, S. 1-21, 2005. https://ul.qucosa.de/id/qucosa%3A14453.

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The use of laser-based optical techniques for medical imaging is an attractive alternative to other methods that utilize ionizing radiation. Beside being non-carcinogenic, it is non-invasive, the equipment is transportable, and the methodology can be used to examine properties of soft tissue. However, unlike x-ray photons, optical photons generated in the near-infrared suffer significant amounts of scattering by heterogeneous bodies (e.g., organelles) found in biological tissue. Thus, theory is required to interpret experimental data which appear in the form o spatially or temporally varying l
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26

Valet, Manon. "Transport properties in biomimetic tissues." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS397.

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Dans ce travail nous développons un modèle expérimental biomimétique de la communication cellule-cellule. Il s'agit de réseaux de gouttelettes aqueuses baignant dans l'huile et reliées par des bicouches lipidiques ornées de canaux ioniques. Pour produire ces réseaux de gouttelettes, nous développons d'abord une méthode d'impression originale basée sur l'extraction périodique à travers une interface huile/air d'un capillaire dans lequel la phase aqueuse est injectée. Nous incorporons ensuite aux bicouches un canal ionique – l’hémolysine - pour étudier la diffusion d'une sonde fluorescente dans
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27

He, Bai-sen. "Osmotic dehydration in plant tissues." Thesis, Aston University, 2005. http://publications.aston.ac.uk/12236/.

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The primary aim of the thesis is to provide a comprehensive investigation of the osmotic dehydration processes in plant tissue. Effort has been concentrated on the modelling for simulating the processes. Two mathematical models for simulating the mass transfer during osmotic dehydration processes in plant tissues are developed and verified using existing experimental data. Both models are based on the mechanism of diffusion and convection of any mobile material that can transport in plant tissues. The mass balance equation for the transport of each constituent is established separately for int
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Casas, ferrer Laura. "Microfluidic flow of biomimetic tissues." Thesis, Université de Montpellier (2022-….), 2022. http://www.theses.fr/2022UMONS001.

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Nous avons conçu un prototissu biomimétique comme modèle de tissus cellulaires qui permet d'identifier le rôle individuel des différents constituants cellulaires qui jouent un rôle dans le comportement rhéologique des tissus. L'objectif final est de caractériser le comportement d'écoulement de ce prototissu sous confinement microfluidique. La première partie de la thèse se concentre sur la conception et la synthèse du prototissu à partir de l'assemblage de Vésicules Unilamellaires Géantes (GUVs). Le système ligand-récepteur que nous avons utilisé pour l'assemblage est la paire streptavidine-bi
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Hossler, Fred E. "Ultrastructure Atlas of Human Tissues." Digital Commons @ East Tennessee State University, 2014. http://amzn.com/1118284534.

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Presents a variety of scanning and transmission electron microscope images of the major systems of the human body. This book looks at the structure and function of tissues at the subcellular and molecular level, an important perspective in understanding and combating diseases.<br>https://dc.etsu.edu/etsu_books/1047/thumbnail.jpg
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Kilaru, Aruna. "Oil Biosynthesis in Nonseed Tissues." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/4768.

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31

Lu, Jike Faculty of Medicine UNSW. "Transplantation of nasal olfactory tissues into transected spinal cord of adult rats." Awarded by:University of New South Wales, 2000. http://handle.unsw.edu.au/1959.4/17798.

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Transplants of olfactory ensheathing cells (OECs) from olfactory bulbs have recently been shown to support regrowth and reinnervation of damaged spinal cord, which has led to improved functional recovery. Using complete transection in adult rat, the studies presented in this thesis examine the role of peripherally derived olfactory tissue in promoting axonal regeneration and functional recovery. Chapter One and Two provide the background to the area of spinal cord regeneration and the methods used in this thesis. Chapter Three shows that transplants of OECs from rat olfactory lamina propria (O
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32

Mukherjee, Indra Neil. "A rational design approach for the cryopreservation of natural and engineered tissues." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/22579.

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Thesis (Ph. D.)--Chemical and Biomolecular Engineering, Georgia Institute of Technology, 2008.<br>Committee Chair: Sambanis, Athanassios; Committee Member: Long, Jr., Robert C.; Committee Member: Ludovice, Peter J.; Committee Member: Prausnitz, Mark R.; Committee Member: Song, Ying C.
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33

Chan, Kwok-Kwan. "Treatment of tissues by ultrasound hyperthermia and the surgical removal of tissues by ultrasonic vibrator/aspirator." Thesis, University of Aberdeen, 1986. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU367488.

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My thesis is composed of two parts. Ultrasound hyperthermia is emphasised in part i, and surgical removal of tissues by ultrasonic surgical aspirator is emphasized in part ii. A hyperthermia system making use of overlapping five divergent ultrasonic beams has been developed in my studies. The system is microcomputer controlled. Tissue temperatures are monitored every 30 seconds during treatment with thermocouple arrays, and then the computer adjusts the hyperthermia applicator's output to reach and maintain the therapeutic temperature level in the treated volume. One of the features of the hyp
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34

Skvortsova, Yulia Alexandrovna Geng M. Lei. "Simulation of tissues for biomedical applications." [Iowa City, Iowa] : University of Iowa, 2009. http://ir.uiowa.edu/etd/436.

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35

Priestman, David Andrew. "Prolinase and prolidase in human tissues." Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/24235.

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36

Newton, Adam J. H. "Modelling adenosine dynamics in neural tissues." Thesis, University of Warwick, 2015. http://wrap.warwick.ac.uk/81484/.

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The neuromodulator adenosine is involved in both physiological and pathological activity, such as sleep, epilepsy and stroke. However, the complex processes underlying the release, transport and clearance of adenosine from the extracellular space and their interactions are still poorly quantified. In this thesis I develop the �rst detailed model of the dynamics of adenosine in neural tissue, including intracellular and extracellular metabolism, using parameters taken from an extensive search of the literature. This approach also identifies physiological and metabolic parameters that have yet t
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Yamamoto, Daniel L. "Adrenergic signaling in insulin-sensitive tissues." Doctoral thesis, Stockholm : Wenner-Gren Institute for Experimental Biology, Stockholm University, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-6668.

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38

Parker, Ines. "Adrenergic mechanisms in rabbit gingival tissues /." Title page, table of contents, summary and declaration only, 1985. http://web4.library.adelaide.edu.au/theses/09DM/09dmp239.pdf.

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39

Chan, Yee-loi, and 陳以來. "Nano-mechanical characterization of dental tissues." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B44764480.

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40

Yang, Teo Heng Jimmy. "Structure-property relationships in biological tissues." Thesis, Heriot-Watt University, 2007. http://hdl.handle.net/10399/90.

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41

Berry, Gearóid Paul. "Acoustic poroelasticity imaging of biological tissues." Thesis, Institute of Cancer Research (University Of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436325.

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42

Regini, Justyn Wiktor. "Order-disorder phenomena in polyelectrolyte tissues." Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239688.

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43

Sandholzer, Michael. "Heat-induced alterations of dental tissues." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/5049/.

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In forensic investigations involving severely burned human remains, dental analysis stands alone as other means of identification are often destroyed. Therefore, the aim of the present work was to investigate the influence of duration of heat exposure and heating regimes regarding the macroscopic, compositional, structural and crystalline alterations of dental tissues. Experiments were carried out using 215 freshly extracted human teeth, exposed to temperatures of 400 to 1000°C. Shrinkage and shape preservation was analysed using micro-CT, whilst crystalline alterations were evaluated with syn
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Sebastian, Anil. "Recreating bone marrow tissues in vitro." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.528263.

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45

Baish, James W., and Rakesh Jain. "Diffusion in tumors and normal tissues." Diffsuion fundamentals 16 (2011) 4, S. 1, 2011. https://ul.qucosa.de/id/qucosa%3A13733.

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46

Troutman, Mr Eric Christopher. "Hypothermic Machine Perfusion of Composite Tissues." Thesis, Virginia Tech, 2017. http://hdl.handle.net/10919/81272.

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Organ perfusion systems have successfully been applied to solid organ preservation and subsequent transplantation. However, their use in limb preservation for Vascularized Composite Tissue Allotransplantation (VCA) has yet to be thoroughly investigated. This thesis explores the potential for hypothermic machine perfusion in prolonging limb graft viability in a swine forelimb amputation model. The experiment was designed with the right and left forelimbs from the same pig randomly assigned to the treatment and control groups. Eighteen (18) limbs were procured from a local abattoir, vessels cann
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47

Basan, Markus. "Physics of cellular tissues and cancer." Paris 6, 2010. http://www.theses.fr/2010PA066115.

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Dans cette thèse, nous développons des descriptions théoriques des tissus cellulaires basées sur une modélisation continue ainsi que sur des simulations numériques. Nous formulons un modèle continu de croissance tumorale qui ne dépend que de quelques paramètres macroscopiques effectifs qui peuvent être déterminés expérimentalement. En particulier, nous proposons que chaque tissu se régule in vivo à une pression qui lui est propre - que nous avons appelée pression homéostatique – et que différentes valeurs de cette pression pour différents tissus prédise le résultat de leur compétition en espac
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48

Kolesky, David Barry. "3D Bioprinting of Vascularized Human Tissues." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493427.

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The ability to manufacture human tissues that replicate the spatial, mechano-chemical, and temporal aspects of biological tissues would enable myriad applications, including drug screening, disease modeling, and tissue repair and regeneration. However, given the complexity of human tissues, this is a daunting challenge. Current biofabrication methods are unable to fully recapitulate the form and function of human tissues, which are composed of multiple cell types, extracellular matrices, and pervasive vasculature. My Ph.D. thesis focuses on advancing the capabilities of human tissue fabricati
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Zijp, Jacob Rudolf. "Optical properties of dental hard tissues." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2001. http://irs.ub.rug.nl/ppn/315857544.

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Baish, James W., and Rakesh Jain. "Diffusion in tumors and normal tissues." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-184556.

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