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1

BONNET, M., I. LOUVEAU, I. CASSAR-MALEK, L. LEFAUCHEUR, and P. Y. RESCAN. "Comprendre le développement des muscles et des tissus adipeux : un préalable pour maîtriser les qualités des carcasses et des produits des animaux d’élevage." INRA Productions Animales 28, no. 2 (2020): 137–50. http://dx.doi.org/10.20870/productions-animales.2015.28.2.3021.

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Les qualités des carcasses et des viandes/chairs des espèces d’intérêt agronomique (mammifères, espèces aviaires et poissons) dépendent en grande partie des caractéristiques et des proportions relatives des différents compartiments tissulaires, principalement les fibres et le tissu conjonctif musculaires et les tissus adipeux. Dans cette revue, nous décrivons la mise en place de ces trois compartiments au cours du développement embryonnaire et foetal, ainsi que leur croissance après la naissance ou l’éclosion. Les fibres musculaires et le tissu conjonctif des muscles du tronc sont issus de dom
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2

Meek, Jennifer, and Eileen D. Adamson. "Transferrin in foetal and adult mouse tissues: synthesis, storage and secretion." Development 86, no. 1 (1985): 205–18. http://dx.doi.org/10.1242/dev.86.1.205.

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Transferrin is an important growth-promoting serum glycoprotein synthesized chiefly in the liver in adults. The transferrin found in the mouse foetus is thought to be wholly a product of the foetus itself and its synthesis starts at least as early as the 7th day of gestation. The major sites of synthesis in mouse foetuses are the visceral yolk sac (VYS) and liver (Adamson, 1982). We now report that other murine foetal tissues synthesize readily detectable amounts, namely lung, spleen, spinal cord and rib cage. Very low levels are also synthesized by the brain, muscle and pancreas. We can detec
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3

Adam, C. L., I. McDonald, C. E. Moir, and R. I. Smart. "Foetal development in red deer (cervus elaphus) 2. Chemical composition of the foetus and associated tissues." Animal Science 46, no. 1 (1988): 139–46. http://dx.doi.org/10.1017/s0003356100003202.

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ABSTRACTThe concentrations of dry matter (DM), crude protein (CP), fat and ash were determined for 18 singleton red deer foetuses of known gestational ages within the range 72 to 224 days (term = 233 days) and for their associated placentae and empty uteri. In addition, concentrations of Ca, P, Mg, Na and K were determined for the foetuses. The amniotic and allantoic fluids were analysed for DM, CP and ash content.Concentrations of all measured components in the foetal fluids increased with foetal age (except for amniotic ash concentration which decreased) and linear regressions were fitted. C
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4

AUROUSSEAU, B., D. DURAND, and D. GRUFFAT. "Contrôle des phénomènes oxydatifs pendant la gestation chez les monogastriques et les ruminants." INRAE Productions Animales 17, no. 5 (2004): 339–54. http://dx.doi.org/10.20870/productions-animales.2004.17.5.3607.

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Chez les mammifères, les phénomènes radicalaires sont impliqués dans la multiplication, la différenciation, la croissance et le fonctionnement des différents types de cellules. Ils jouent un rôle très important pendant la gestation. L’intensité du métabolisme utéro-placentaire et embryonnaire, favorisée par la sécrétion des oestrogènes, stimule en effet la production de radicaux libres oxygénés à différents niveaux de la cellule (notamment dans les mitochondries). Ceux-ci interviennent dans la fusion des membranes, permettant la nidation de l’oeuf fécondé et le remodelage des tissus utérins, p
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5

Tewe, O. Q., and J. H. Maner. "INFLUENCE OF DIETARY INORGANIC CYANIDE (KCN) ON PLACENTAL THIOCYANATE TRANSFER, TISSUE RIIODANESE ACTIVITY AND PERFORMANCE OF RATS DURING GESTATION." Nigerian Journal of Animal Production 9, no. 1 (2021): 53–57. http://dx.doi.org/10.51791/njap.v9i1.2282.

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Thirty two bred rats were allotted to two diets to investigate the influence of non-addition or addition of 1000 ppm KCN to cassava — soybean diets on thiocyanate concentrations, tissue rhodanese activity and performance parameters. KCN caus­ed a non-significant (P>0.05) depres­sion in body weight gain but had no effect on weights of liver, kidney and placenta, nor on number and weight of 19 day old foetus. High (1000 ppm) KCN level caused a significant (P<0.05) increase in urinary thiocyanate excretion of thiocyanate. It however had no marked effect on serum protein bound 'iodine, ammio
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6

Werkman, M., J. A. Rooke, K. McIlvaney, C. M. Dwyer, and C. J. Ashworth. "Effects of mild early-and mid-pregnancy under-nutrition on foetal and placental development in Scottish Blackface and Suffolk sheep." Proceedings of the British Society of Animal Science 2009 (April 2009): 73. http://dx.doi.org/10.1017/s1752756200029124.

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Nutrient intake during pregnancy affects foetal development and placental function in a range of species, often with long-term effects on offspring viability. Maternal nutrient supply is believed to affect the ability of the placenta to deliver nutrients to the foetus (Fowden et al., 2006). In ruminant species, the majority of placental nutrient transport occurs in specialised structures called placentomes, which are categorised into 4 types (A-D) based on their morphological appearance. In type A placentomes, maternal tissue surrounds foetal tissues, whereas type D placentomes are typically e
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7

Wojtasiak, Natalia, Tomasz Stankiewicz, and Jan Udała. "Ultrasound examination of pregnancy in the domestic goat (Capra hircus) ‒ a review." Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego 16, no. 2 (2016): 65–78. http://dx.doi.org/10.5604/01.3001.0014.2019.

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Ultrasonography (USG) for embryo-foetal foetometry is widely used in the management of goat breeding. Tissues and organs of the embryo/foetus are measured and evaluated to assess gestational age. Transrectal, transabdominal and transvaginal probes are used to perform the ultrasound examination. Technological advances, especially with regard to ultrasound image resolution, enable precise visualization of embryo-foetal structures in goats. The article reviews the foetometric measurements used in ultrasound examination of pregnancy in goats. Performing this examination during specific periods of
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8

Reynolds, L. P., C. L. Ferrell, Debra A. Robertson, and S. P. Ford. "Metabolism of the gravid uterus, foetus and utero-placenta at several stages of gestation in cows." Journal of Agricultural Science 106, no. 3 (1986): 437–44. http://dx.doi.org/10.1017/s0021859600063309.

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SummaryTo quantify changes in rates of metabolism and nutrient uptake of gravid uteiine, foetal and utero-placental tissues throughout gestation, mature Hereford cows received surgery at 132 ± 0·6 (n = 12), 176 ± 0·5 (n = 8), 220 ±0·4 (n = 11) and 245 ±1·5 (n = 7) days after mating. Indwelling catheters were implanted into a uterine artery and vein of all cows. Foetal catheters also were implanted into an umbilical vein and foetal femoral artery and vein (days 176 and 220) or into a placental artery and two placental veins (days 132 and 245). Approximately 5 days after surgery, deuterium oxide
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9

Grinspon, Romina P., and Rodolfo A. Rey. "Molecular Characterization of XX Maleness." International Journal of Molecular Sciences 20, no. 23 (2019): 6089. http://dx.doi.org/10.3390/ijms20236089.

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Androgens and anti-Müllerian hormone (AMH), secreted by the foetal testis, are responsible for the development of male reproductive organs and the regression of female anlagen. Virilization of the reproductive tract in association with the absence of Müllerian derivatives in the XX foetus implies the existence of testicular tissue, which can occur in the presence or absence of SRY. Recent advancement in the knowledge of the opposing gene cascades driving to the differentiation of the gonadal ridge into testes or ovaries during early foetal development has provided insight into the molecular ex
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10

Varma, Santosh K., and Eric Bloch. "Effects of prenatal administration of mestranol and two progestins on testosterone synthesis and reproductive tract development in male rats." Acta Endocrinologica 116, no. 2 (1987): 193–99. http://dx.doi.org/10.1530/acta.0.1160193.

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Abstract. The oestrogen mestranol (0, 0.01, 0.1 mg/kg body weight per day) and the progestins medroxyprogesterone-acetate and norethisterone (0, 2, 20 mg/kg body weight per day each) in sesame oil were intubated intragastrically daily during gestational days 14.5 through 19.5 to pregnant rats. Males were studied as 20.5-day-old foetuses and 4-month-old adults for serum testosterone and LH concentrations, in vitro testosterone synthesis, anogenital distance (foetuses only) and testes, seminal vesicle and ventral prostate weights. Administration of 0.1 mg mestranol decreased by 35 to 70% basal a
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11

Oepkes, Dick, and Monique Haak. "Extracardiac malformations: associations and importance: consequences for perinatal management of foetal cardiac patients." Cardiology in the Young 24, S2 (2014): 55–59. http://dx.doi.org/10.1017/s1047951114001425.

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AbstractFoetal echocardiography has become an established subspecialty in paediatric cardiology. The skills to perform detailed assessment of foetal cardiac anomalies in a tiny, moving foetus surrounded by sometimes challenging layers of maternal tissue are not easy to obtain, and require prolonged periods of specific training and supervised scanning in expert centres. The goal of this overview is to discuss the importance of the awareness of the fact that expert examination of the foetal heart and in-depth knowledge of newborn surgical interventions are only a part of the picture; many cardia
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12

Catt, J. W., F. L. Harrison, and J. S. Carleton. "Distribution of an endogenous beta-galactoside-specific lectin during foetal and neonatal rabbit development." Journal of Cell Science 87, no. 5 (1987): 623–33. http://dx.doi.org/10.1242/jcs.87.5.623.

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The tissue concentration of an endogenous beta-galactoside-specific lectin is developmentally regulated in rabbit tissues during foetal and neonatal development. Immunoassay data and localization studies both indicate that the lectin is particularly associated with late embryonic and early postnatal development. No lectin could be detected in embryos prior to 21 days of gestation, whereas many tissues showed an increase in lectin around the time of birth. It is likely that in most tissues the high concentrations of lectin are largely due to increased synthesis by fibroblasts, which are particu
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13

Abiola, S. S. "THE SALVAGE OF BOVINE FOETUSES IN SLAUGHTERED CATTLE WITHIN OGUN STATE, NIGERIA." Nigerian Journal of Animal Production 24, no. 1 (2021): 76–78. http://dx.doi.org/10.51791/njap.v24i1.2358.

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Bovine fetuses recovered from abattoirs and slaughter slabs in Ogun State were previously discarded. Recently, a total of 327 skins of fetuses in the third trimester were tanned to produce leather for the manufacture of 439 pairs of shoes which yielded a revenue of N33,124 for the State Government. The skins of foetuses in both the first and second trimesters were used in the manufacture of local drums. Foetal carcases were processed as pet foods by dog and cat owners. Some foetal tissues could be preserved for use in the laboratories for research purposes. Such utilization of foetus has reduc
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14

Pekonen, F., K. Rosenlöf, E. M. Rutanen, and F. Fyhrquist. "Erythropoietin binding sites in human foetal tissues." Acta Endocrinologica 116, no. 4 (1987): 561–67. http://dx.doi.org/10.1530/acta.0.1160561.

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Abstract. Using 125I labelled recombinant DNA human erythropoietin (EP), we have explored the presence and properties of EP binding sites in foetal human tissues. The EP binding site is present in the foetal liver already during the first trimester of pregnancy. The binding site has an equilibrium association constant of 4.1–6.2 × 109 1/mol and is specific for EP. The cross-reactivities of FSH, TSH, hCG, insulin and renin substrate were less than 0.01%. The EP binding capacity of foetal liver was 5.4–16 fmol/mg membrane protein. In foetal lung tissue, a slight EP binding activity was observed,
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15

Hofstee, Pierre, James S. M. Cuffe, and Anthony V. Perkins. "Analysis of Selenoprotein Expression in Response to Dietary Selenium Deficiency During Pregnancy Indicates Tissue Specific Differential Expression in Mothers and Sex Specific Changes in the Fetus and Offspring." International Journal of Molecular Sciences 21, no. 6 (2020): 2210. http://dx.doi.org/10.3390/ijms21062210.

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The human selenoproteome is comprised of ~25 genes, which incorporate selenium, in the form of selenocysteine, into their structure. Since it is well known that selenium is important to maternal health and foetal development during pregnancy, this study aimed at defining the impact of selenium deficiency on maternal, placental, foetal and offspring selenoprotein gene expression. Female C57BL/6 mice were randomly allocated to control (>190 μg/kg) or low selenium (<50 μg/kg) diets four weeks prior to mating and throughout gestation. At embryonic day (E)18.5, pregnant mice were sacrificed f
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16

Maitland, Janice E., Ian D. Caterson, Rebecca E. Gauci, Jennifer A. Spaliviero, and John R. Turtle. "Organ culture of human foetal pancreas: conditions which affect basal and stimulated insulin release." Acta Endocrinologica 108, no. 3 (1985): 377–85. http://dx.doi.org/10.1530/acta.0.1080377.

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Abstract. Human foetal pancreas has been maintained in organ culture with net synthesis and release of insulin for up to 60 days. The age of the donor foetus affected the basal insulin release rate. A plateau of secretion was reached with foetuses of ≥ 16 weeks of gestation. Explants cultured within 2 h of expulsion following prostaglandin induced termination secreted 3.0 times more insulin after 20 days of culture than those cultured within 2–4 h and 8.1 times more than those cultured more than 4 h post-termination. A high oxygen environment was toxic to the explants during culture. Fresh tis
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17

Saggerson, E. D., and C. A. Carpenter. "Carnitine palmitoyltransferase in liver and five extrahepatic tissues in the rat. Inhibition by dl-2-bromopalmitoyl-CoA and effect of hypothyroidism." Biochemical Journal 236, no. 1 (1986): 137–41. http://dx.doi.org/10.1042/bj2360137.

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Mitochondria were isolated from rat adult liver, foetal liver, kidney cortex, heart, skeletal muscle and interscapular brown adipose tissue. DL-2-Bromopalmitoyl-CoA inhibited the overt form of carnitine palmitoyltransferase (CPT1) in heart, skeletal muscle and brown adipose tissue, with an IC50 value (concentration giving 50% inhibition) of 1.3-1.6 microM. By contrast, the IC50 value for inhibition of the kidney or adult liver enzyme was 0.08-0.1 microM. CPT1 in near-term foetal liver differed from that in adult liver in that the IC50 for inhibition by 2-bromopalmitoyl-CoA was 0.57 microM. It
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18

Martin, P. "Foetal wound healing tissue repair and foetal wound healing." Journal of Tissue Viability 15, no. 2 (2005): 24–25. http://dx.doi.org/10.1016/s0965-206x(05)52031-x.

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19

Raju, N., G. Ramesh, S. Basha, and S. Ushakumary. "Prenatal development of palatine tonsil in sheep (Ovis aries)." Journal of Morphological Sciences 33, no. 01 (2016): 014–16. http://dx.doi.org/10.4322/jms.073414.

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Abstract Introduction: The palatine tonsil play a key role in initiating immune responses against the antigenic material entering the mouth. Materials and Methods: Tissue pieces of oropharynx for the palatine tonsilwere collected from different prenatal age groups of sheep. These tissue pieces were fixed and processed for routine paraffin embedding technique to get 3-5pm thick sections. The paraffin sections were subjected to routine haematoxylin and eosin and some other special staining methods. Results: In three months foetal age of sheep, the palatine tonsils appeared as diffused lymphocyti
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20

ROBELIN, J. "Différenciation, croissance et développement cellulaire du tissu musculaire." INRAE Productions Animales 3, no. 4 (1990): 253–63. http://dx.doi.org/10.20870/productions-animales.1990.3.4.4384.

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Le tissu musculaire est constitué de fibres allongées, cylindriques, plurinucléées et organisées en faisceaux entourés par une gaine de tissu conjonctif. On distingue différents types de fibres musculaires, selon qu’elles sont alimentées en énergie par la glycolyse en milieu anaérobie, ou par le cycle de Krebs et la chaîne respiratoire en milieu aérobie. On distingue aussi les fibres à contraction lente de celles à contraction rapide. Les cellules musculaires se développent chez l’embryon à partir de la région somitique. Les cellules myogéniques, non encore différenciées se multiplient au cour
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21

Adam, C. L., I. McDonald, C. E. Moir, and K. Pennie. "Foetal development in red deer (cervus elaphus) 1. Growth of the foetus and associated tissues." Animal Science 46, no. 1 (1988): 131–38. http://dx.doi.org/10.1017/s0003356100003196.

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ABSTRACTEighteen pregnant red deer hinds were slaughtered at known stages of gestation between 72 and 224 days (term = 233 days). The udder was removed and the gravid uterus was separated into foetal, placental, empty uterus, amniotic fluid and allantoic fluid components. Equations were fitted to the weights of each component to describe the effects of stage of gestation. Hind weight at mating had no significant effect. For the foetal weight (Y, kg) the data were closely fitted by a version of the Gompertz equation,loge Y = 3·016 — 14·267exp (–0·01138t) – 0·086swhere t is time in days from con
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22

Olayaki, LA, AO Soladoye, and OO Ojo. "Melatonin improves diabetes-induced foetal growth retardation in rats." Bangladesh Pharmaceutical Journal 18, no. 1 (2015): 42–47. http://dx.doi.org/10.3329/bpj.v18i1.23514.

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The aim of the present study was to investigate the effect of oral melatonin administration on foetal growth retardation, utero-placental antioxidant enzymes activities and lipid peroxidation in experimental diabetic rats. Twenty pregnant rats were divided into four groups of five rats each. Diabetes mellitus was induced by a single intraperitoneal administration of 120mg/kg body weight of alloxan. From gestational day 5 to 19, 5mg/kg and 10mg/kg of oral melatonin were administered to the rats with clearly manifested gestational diabetes. On the 19th day of gestation, the rats were sacrificed
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23

Larqué, Elvira, Eva Morales, Rosaura Leis, and José E. Blanco-Carnero. "Maternal and Foetal Health Implications of Vitamin D Status during Pregnancy." Annals of Nutrition and Metabolism 72, no. 3 (2018): 179–92. http://dx.doi.org/10.1159/000487370.

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Background: To what extent does the circulating 25-hydroxyvitamin D (25[OH]D) concentration help to meet the physiological needs of humans is an ongoing subject of debate. Remaining unexposed to the sun to reduce melanoma cancer risk, current lifestyle with less out door activities, and increasing obesity rates, which in turn increases the storage of vitamin D in the adipose tissue, are presumably factors that contribute to the substantial upsurge in the prevalence of vitamin D deficiency in humans. Since evidence is lacking regarding the appropriate cut-off points to define vitamin D status d
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24

Mokkala, K., H. Röytiö, U. Ekblad, and K. Laitinen. "Opportunities for probiotics and polyunsaturated fatty acids to improve metabolic health of overweight pregnant women." Beneficial Microbes 8, no. 1 (2017): 3–15. http://dx.doi.org/10.3920/bm2016.0068.

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Overweight during pregnancy predisposes both the mother and foetus to health complications. Maternal complications include gestational diabetes, obstetric problems and type 2 diabetes later in life. Complications for the offspring are not only restricted to the foetal period or birth, such as prematurity and foetal macrosomia, but may also have long-term metabolic health implications through the mechanism of early nutrition programming. One of the key metabolic components characterising overweight in the non-pregnant state is low-grade inflammation manifested by elevated levels of circulatory
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25

Alsalami, Mohammed T. "Desmosome-like structure between lymphocytes of developing thymus of foetal lamb." Proceedings, annual meeting, Electron Microscopy Society of America 48, no. 3 (1990): 456–57. http://dx.doi.org/10.1017/s0424820100159825.

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The foetal thymuses of sheep from 40 days to full term gestation were studied. The earliest thymuses that were studied were obtained from foetuses of 40 days gestation. At this stage of development the thymic tissue was formed of cords of condensed epithelial cells. Lymphopoiesis occurred in these thymuses between the thymus of 40 day old foetus and those of 42 days was striking and indicated that the onset of lymphopoiesis in the foetal sheep occurred abruptly. From 42 days onwards there was a rapid increase in the size of the thymus and in the extent of the lymphopoiesis (Fig. 1). By 45 days
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26

Trebichavsky, I. "Distribution of fibronectin in foetal tissues." Cell Biology International 19, no. 10 (1995): 813–20. http://dx.doi.org/10.1006/cbir.1995.1015.

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27

Videmann, B., F. Koraichi, M. Mazallon, and S. Lecoeur. "Effect of gender, pregnancy and exposure conditions on metabolism and distribution of zearalenone in rats." World Mycotoxin Journal 5, no. 1 (2012): 57–69. http://dx.doi.org/10.3920/wmj2011.1319.

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The mycotoxin zearalenone (ZEA) is produced by a variety of Fusarium fungi and contaminates numerous cereals, fruits and vegetables. Interacting with the oestrogen receptors, ZEA and reduced metabolites zearalenols (ZOLs) cause hormonal effects in animals, such as abnormalities in the development of the reproductive tract and mammary gland in female offspring. Limited information is available on the pharmacokinetics of ZEA and its metabolites, particularly in pregnant females, foetuses and newborns. Our study was conducted to characterise the tissue distribution and metabolism of ZEA in male a
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28

Stenhouse, Claire, Charis O. Hogg, and Cheryl J. Ashworth. "Association of foetal size and sex with porcine foeto-maternal interface integrin expression." Reproduction 157, no. 4 (2019): 317–28. http://dx.doi.org/10.1530/rep-18-0520.

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Integrins regulate adhesion at the foeto-maternal interface by interacting with secreted phosphoprotein 1 (SPP1) and fibronectin (FN). It is hypothesised that impaired foetal growth of ‘runt’ piglets is linked to altered integrin signalling at the foeto-maternal interface. Placental and endometrial samples associated with the lightest and closest to mean litter weight (CTMLW) (gestational day (GD18, 30, 45, 60 and 90), of both sex (GD30, 45, 60 and 90) (n = 5–8 litters/GD), Large White × Landrace conceptuses or foetuses were obtained. The mRNA expression of the integrin subunits (ITG) ITGA2, I
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29

Basu, Barnali, Ranjan Shetty, and Krishnendu Gupta. "Assessment of foetal cardiac function by myocardial tissue doppler in foetal growth restriction." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 3 (2017): 1045. http://dx.doi.org/10.18203/2320-1770.ijrcog20170582.

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Background: One of the consequences of IUGR is the development of cardiac diastolic dysfunction in fetuses. Tissue doppler in echocardiography is a new technique to detect myocardial tissue function and can act as a useful tool in the identification of this complication. Hence we decided to undertake this study to assess the utility of myocardial tissue doppler in detecting foetal cardiac dysfunction in IUGR. It was a prospective case control study in a tertiary care teaching hospital.Methods: Foetal cardiac function in the third trimester of pregnancy was evaluated with the help of myocardial
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30

Teruel, T., A. M. Valverde, A. Alvarez, M. Benito, and M. Lorenzo. "Differentiation of rat brown adipocytes during late foetal development: role of insulin-like growth factor I." Biochemical Journal 310, no. 3 (1995): 771–76. http://dx.doi.org/10.1042/bj3100771.

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Rat brown adipocytes at day 22 of foetal development showed greater size, higher mitochondria content and larger amounts of lipids, as determined by flow cytometry, than 20-day foetal cells. Simultaneously, an inhibition on the percentage of brown adipocytes into S+G2/M phases of the cell cycle was observed between days 20 and 22 of foetal development. The expression of several adipogenesis-related genes, such as fatty acid synthase, malic enzyme, glucose-6-phosphate dehydrogenase and insulin-regulated glucose transporter, increased at the end of foetal life in brown adipose tissue. In additio
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Okabe, Ryo, Toyofumi F. Chen-Yoshikawa, Akihiko Yoshizawa, et al. "Orthotopic foetal lung tissue direct injection into lung showed a preventive effect against paraquat-induced acute lung injury in mice." European Journal of Cardio-Thoracic Surgery 58, no. 3 (2020): 638–45. http://dx.doi.org/10.1093/ejcts/ezaa091.

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Abstract OBJECTIVES Lung transplantation is the only effective therapy for patients with end-stage lung disease but an organ shortage crisis necessitates the development of alternative therapies. Recent studies have highlighted the potential of foetal tissue transplantation to facilitate the regeneration of vital organs such as liver that have been damaged by lethal diseases. Herein, with the aim of restoring pulmonary function, we hypothesized that allogenic foetal lung tissue implantation would attenuate severe respiratory failure. METHODS Lung tissue from the foetuses of pregnant green fluo
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32

Julkunen, Mervi. "Human decidua synthesizes placental protein 14 (PP 14) in vitro." Acta Endocrinologica 112, no. 2 (1986): 271–77. http://dx.doi.org/10.1530/acta.0.1120271.

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Abstract. Human decidua was found to synthesize and secrete placental protein 14 (PP14). The presence of PP14 in tissue explants of decidua, foetal membranes and placenta from term pregnancy was demonstrated by radioimmunoassay. The PP14 content in decidua (1300 ±410 ng/100 mg tissue) was higher than in chorion (570 ± 120 ng/100 mg; P < 0.01), amnion (240 ± 100 ng/100 mg; P < 0.001) or placenta (300 ± 130 ng/100 mg; P< 0.001). Three to 36 times more PP14 was released into culture medium by decidual explants compared with the other tissues, and cycloheximide decreased this release by 3
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33

Wilharm, Anneke, Helena C. Brigas, Inga Sandrock та ін. "Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance". Mucosal Immunology 14, № 1 (2020): 242–52. http://dx.doi.org/10.1038/s41385-020-0330-6.

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AbstractγδT cells represent the majority of lymphocytes in several mucosal tissues where they contribute to tissue homoeostasis, microbial defence and wound repair. Here we characterise a population of interleukin (IL) 17-producing γδ (γδ17) T cells that seed the testis of naive C57BL/6 mice, expand at puberty and persist throughout adulthood. We show that this population is foetal-derived and displays a T-cell receptor (TCR) repertoire highly biased towards Vγ6-containing rearrangements. These γδ17 cells were the major source of IL-17 in the testis, whereas αβ T cells mostly provided interfer
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Streyl, Dominik, Rebecca Kenngott, Nadja Herbach, et al. "Gene expression profiling of bovine peripartal placentomes: detection of molecular pathways potentially involved in the release of foetal membranes." REPRODUCTION 143, no. 1 (2012): 85–105. http://dx.doi.org/10.1530/rep-11-0204.

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The mechanisms underlying detachment of foetal membranes after birth in cows are still unclear. To address this problem in a systematic manner, we performed the first holistic transcriptome study of bovine placentomes antepartum (AP;n=4 cows) and intrapartum (IP;n=4 cows) using Affymetrix GeneChip Bovine Genome Arrays. Three placentomes were extracted from each cow, and tissue samples from the contact zones of the placentomes (foeto-maternal units) were recovered by systematic random sampling and processed for RNA extraction and for stereological quantification of cellular composition. Statist
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Nguyen-Ngo, Caitlyn, Carlos Salomon, Andrew Lai, Jane C. Willcox, and Martha Lappas. "Anti-inflammatory effects of gallic acid in human gestational tissues in vitro." Reproduction 160, no. 4 (2020): 561–78. http://dx.doi.org/10.1530/rep-20-0249.

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Spontaneous preterm birth is the leading cause of neonatal mortality and morbidity globally. Activation of the maternal immune system leads to a downstream cascade of proinflammatory events that culminate in the activation of spontaneous uterine contractions and the rupture of the foetal membranes. Anti-inflammatory agents may be a novel therapeutic approach to prevent inflammation-induced myometrial contractions and premature rupture of foetal membranes. The polyphenol gallic acid has been previously shown to exert potent anti-inflammatory effects. Thus, this study aimed to determine the effe
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Kikuchi, Kiyoshi, Kazuwa Nakao, Ken Hayashi, et al. "Ontogeny of atrial natriuretic polypeptide in the human heart." Acta Endocrinologica 115, no. 2 (1987): 211–17. http://dx.doi.org/10.1530/acta.0.1150211.

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Abstract. To elucidate the developmental changes of atrial natriuretic polypeptide in the human heart, we studied α-human atrial natriuretic polypeptide (α-hANP)-like immunoreactivity (α-hANP-LI) in the extracts from the hearts of three foetuses of 10, 14 and 22 weeks' gestation, a 1-day-old premature infant of 33 weeks' gestation, and two adults. α-hANP-LI levels in the atria of the three foetuses of 10, 14 and 22 weeks' gestation and the premature infant (31.4, 12.2, 9.25 and 15.3 nmol/g, respectively) were comparable to those in two adult atria (16.9 and 13.6 nmol/g). The ventricles also co
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Clarke, L., S. van de Waal, M. A. Lomax, and M. E. Symonds. "Brown adipose tissue development in the ovine foetus during the final month of gestation." BSAP Occasional Publication 15 (1992): 174–75. http://dx.doi.org/10.1017/s0263967x00004225.

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In the ovine foetus brown adipose tissue (BAT) is mainly found in the perirenal region and grows rapidly relative to body weight between 70 to 120 days of gestation (Alexander, 1978). After this stage only a small amount of BAT growth occurs in comparison with that of the whole foetus, and in the case of undernutrition may decline (Alexander, 1978). Maternal cold stress, induced by winter shearing twin-bearing pregnant ewes 8 weeks before parturition improves lamb birth weight and lamb growth rate independently of effects on maternal food intake (Symonds, Bryant and Lomax, 1986 and 1990). At t
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Smok, Carolina, Ignacio Roa, and Mariana Rojas. "Foetal Development in Mammals." International Journal of Medical and Surgical Sciences 1, no. 2 (2018): 139–45. http://dx.doi.org/10.32457/ijmss.2014.017.

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During the fetal period are carried out a series of necessary changes, which prepare the fetus for extrauterine life, culminating embryonic development, leading to this physiological maturation of tissues, organs and systems, along with a rapidly growing body. Well being bought, the species-specific features. Other events of interest are beginning the process of ossification of the bones (short and long), formation of the eyelids; integumentary and other elements besides the surfactant secretion from lungs. In this paper we will make a description of the main events that characterized this per
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Kulkarni, Ketki S., Purnima R. Satoskar, Vandana Bansal, and Rachana Kharate. "Foetal arrhythmias: an enigma of the missed beats." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 12 (2018): 4862. http://dx.doi.org/10.18203/2320-1770.ijrcog20184930.

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Background: The synchronised depolarization and repolarisation of the atria and ventricles is achieved by specialised cardiac cells that generate an electrical impulse and propagate it along the conducting system in the myocardial tissue, leading to rhythmic activity of the atria and ventricles. Abnormalities of these rhythms lead to foetal arrhythmia.Methods: A retrospective observational study was conducted in a tertiary care hospital over period of one year to study the course and perinatal outcome of women with foetal arrhythmias.Results: The confinement in the study period was N=4302, of
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Kiss, E., and Á. Szappanos. "THU0595 SUCCESSFUL COMBINED IMMUNE-MODULATING THERAPY OF IN UTERO MYOCARDITIS AS THE MANIFESTATION OF NEONATAL LUPUS IN A RO/SS-A ANTIBODY EXPOSED NEWBORN." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 539.2–540. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6374.

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Background:Congenital heart block (CHB) occurs in 2-5% of pregnancies due to maternal Ro/SSA and/or anti-La/SSB antibodies, and has a recurrence rate of 12-20% in the following pregnancy. The highest risk for CHB of the foetus is in the gestational age between 16- and 28-weeks. Without immunotherapy, this autoantibody mediated disorder comes with substantial mortality with a rate of 15-30%. Ro/SSA and/or anti-La/SSB antibodies attack the atrioventricular node with the subsequent inflammation and fibrosis. In addition, other cardiac manifestations are known such as endocardial fibroelastosis, d
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B, Janssen, Martens D, Penders J, et al. "Linking mitochondrial and telomere damage in foetal tissue." Environmental Epidemiology 3 (October 2019): 180. http://dx.doi.org/10.1097/01.ee9.0000607780.55478.41.

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Symonds, Phillips, Anthony, Owens, and McMillen. "Prolactin Receptor Gene Expression and Foetal Adipose Tissue." Journal of Neuroendocrinology 10, no. 11 (1998): 885–90. http://dx.doi.org/10.1046/j.1365-2826.1998.00275.x.

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Kershaw, T. R., and J. D. Sinden. "Survival of Foetal Neural Tissue from the H-2Kb-tsA58 Transgenic Mouse Grafted to Adult Mouse Brain." Cell Transplantation 2, no. 3 (1993): 215–22. http://dx.doi.org/10.1177/096368979300200305.

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Many recent studies have used a temperature sensitive strain of the simian virus 40 large tumor antigen gene (tsA58) to immortalise foetal neural cells by gene insertion in vitro. The H-2Kb-tsA58 transgenic mouse circumvents the need for such genetic manipulation as the tsA58 gene is already within its genome. The results from this study show that foetal neural cells from this mouse do no proliferate and form tumors after grafting to adult brain; rather they survive and differentiate in a manner similar to nontransgenic foetal neural transplants. Therefore, this mouse is a potential source of
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Paulovic, R. P., and R. A. Anwar. "Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta." Biochemical Journal 261, no. 1 (1989): 227–32. http://dx.doi.org/10.1042/bj2610227.

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The data presented clearly suggest that relative amounts of mRNAs for elastins a, b and c are developmentally regulated in foetal-calf nuchal ligament and aorta and that this regulation is tissue-specific. In nuchal ligament, at earlier stages of foetal development, the relative amounts of mRNAs for elastins a and b are very low. After the foetal age of about 6 months the relative amount of mRNA for elastin b begins to increase. This is followed by an increase in the relative amount of mRNA for elastin a. In aorta, with increasing foetal age, the relative amounts of mRNAs for elastins b and c
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IGBOKWE, Casmir O., and Daniel N. EZEASOR. "Age-related Microscopic Changes in the Thyroid Gland of West African Dwarf Goat During Foetal and Post-natal Periods of Development." Notulae Scientia Biologicae 9, no. 1 (2017): 59–66. http://dx.doi.org/10.15835/nsb9110031.

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The histometric and histologic standard techniques were used to provide comprehensive information on the morphological changes in the thyroid gland of West African Dwarf goat during the foetal and postnatal development stages. The foetal age was determined using crown rump length and the pre-pubertal and pubertal age of animals was determined by dentition. The early foetal thyroid, surrounded by a thin capsule of dense irregular connective tissue, was continuous with well vascularised loose connective tissue septa. The parenchyma was composed of solid cell clusters of follicular epithelial cel
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Conley, Alan J., and Barry A. Ball. "Steroids in the establishment and maintenance of pregnancy and at parturition in the mare." Reproduction 158, no. 6 (2019): R197—R208. http://dx.doi.org/10.1530/rep-19-0179.

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Historically, studies on the endocrinology of pregnancy and parturition in horses have made major contributions of relevance to mammals in general. Recent use of liquid chromatography mass spectrometry, measuring multiple steroid hormones simultaneously in blood, foetal and placental tissues throughout normal gestation, and in mares with experimentally induced placentitis, has advanced our current understanding of many of the unusual strategies seen during gestation and at foaling. This includes the stimulation of luteal steroidogeneisis by equine chorionic gonadotropin (eCG) from the endometr
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Milligan, G. "Foetal-calf serum stimulates a pertussis-toxin-sensitive high-affinity GTPase activity in rat glioma C6 BU1 cells." Biochemical Journal 245, no. 2 (1987): 501–5. http://dx.doi.org/10.1042/bj2450501.

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Cellular proliferation of rat glioma C6 BU1 cells in tissue culture is dependent on the presence of either calf or foetal-calf serum in the medium. Foetal-calf serum stimulated a high-affinity GTPase in membranes derived from C6 BU1 cells. Pretreatment of the cells with pertussis toxin decreased the high-affinity GTPase activity substantially, and attenuated the foetal-calf-serum-stimulated increase in this GTPase activity. Cholera toxin, in contrast, did not modulate the response to foetal-calf serum. Foetal-calf serum did not inhibit adenylate cyclase activity in membranes of these cells, in
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48

Iacono, Eleonora, Romina Marcoccia, and Barbara Merlo. "Current Status on Canine Foetal Fluid and Adnexa Derived Mesenchymal Stem Cells." Animals 11, no. 8 (2021): 2254. http://dx.doi.org/10.3390/ani11082254.

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Effective standards of care treatment guidelines have been developed for many canine diseases. However, a subpopulation of patients is partially or completely refractory to these protocols, so their owners seek novel therapies such as treatments with MSCs. Although in dogs, as with human medicine, the most studied MSCs sources have been bone marrow and adipose tissue, in recent years, many researchers have drawn attention towards alternative sources, such as foetal adnexa and fluid, since they possess many advantages over bone marrow and adipose tissue. Foetal adnexa and fluid could be conside
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Goodyer, Cynthia G., Sorana Marcovitz, Jules Hardy, Yves Lefebvre, Harvey J. Guyda, and Barry I. Posner. "Effect of insulin-like growth factors on human foetal, adult normal and tumour pituitary function in tissue culture." Acta Endocrinologica 112, no. 1 (1986): 49–57. http://dx.doi.org/10.1530/acta.0.1120049.

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Abstract. To determine the direct effects of insulin-like growth factors (IGFs) on hormone release by the human pituitary gland, human foetal, adult normal and tumour pituitary tissues were maintained in culture for 2 to 4 weeks and tested with acute (3 h) exposures to different preparations of IGF peptides. Adult normal pituitaries and adenomas were tested with a semipurified preparation of IGFs, free of immunoreactive insulin, containing IGF-I and IGF-II in a ratio of approximately 1:4. Human foetal pituitaries were tested with the semipurified IGFs as well as more purified preparations of I
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50

Dassios, Theodore, Kamal Ali, Ann Hickey, and Anne Greenough. "Transient iatrogenic heart block following foetal intracardiac transfusion for severe twin anaemia-polycythaemia sequence." Case Reports in Perinatal Medicine 5, no. 2 (2016): 127–29. http://dx.doi.org/10.1515/crpm-2016-0004.

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Abstract Background: Intrauterine blood transfusion is an important treatment of foetal anaemia. Although the standard access to the foetal vasculature for transfusion is the umbilical vein, the intracardiac route is used when foetal or placental positions make other accesses technically challenging. Intrauterine, intracardiac blood transfusion is associated with complications including haemopericardium, damage to cardiac tissues and foetal bradycardia. Highlights of the present report: We report a case of monochorionic twins with twin anaemia-polycythaemia sequence (TAPS). Intracardiac, intra
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