Relevant bibliographies by topics / TITAN trial

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  2. Dissertations / Theses
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Academic literature on the topic 'TITAN trial'

Author: Grafiati
Published: 7 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "TITAN trial"

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King, Alexandra. "TITAN trial results published." Nature Reviews Cardiology 9, no. 8 (2012): 433. http://dx.doi.org/10.1038/nrcardio.2012.90.

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Daniel, García Flores, and Armando Pérez Espinoza José. "A Review of TITAN Trial for Prostate Cancer." International Journal of Medical Science and Clinical Research Studies 04, no. 12 (2024): 2398–99. https://doi.org/10.5281/zenodo.14557927.

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The TITAN trial, a phase III, randomized, double-blind, placebo-controlled study, evaluated the efficacy and safety of apalutamide in combination with androgen deprivation therapy (ADT) for patients with metastatic castration-sensitive prostate cancer (mCSPC). The trial included 1,052 patients randomized to receive apalutamide or placebo plus ADT, with primary endpoints of overall survival (OS) and radiographic progression-free survival (rPFS). Results demonstrated that apalutamide significantly improved OS and rPFS, with a 35% reduction in the risk of death (HR, 0.65; 95% CI, 0.53–0.79;
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Goshua, George, Pranay Sinha, Jeanne E. Hendrickson, Christopher A. Tormey, Pavan Bendapudi, and Alfred Ian Lee. "Cost Effectiveness of Caplacizumab in Acquired Thrombotic Thrombocytopenic Purpura." Blood 136, Supplement 1 (2020): 18–19. http://dx.doi.org/10.1182/blood-2020-138515.

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Introduction: Acquired thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease characterized by thrombotic microangiopathy leading to end-organ damage. The standard of care (SOC) treatment is therapeutic plasma exchange (TPE) alongside immunomodulation with steroids, with increasing use of rituximab +/- other immunomodulatory agents. The addition of caplacizumab, a nanobody targeting von Willebrand factor, was shown to accelerate platelet count recovery, reduce TPE treatments and hospital length of stay, decrease exacerbations and increase relapses in TTP patients treated in th
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Ozay, Zeynep Irem, Scott C. Morgan, Kim N. Chi, et al. "Association of statin use with overall survival and cardiac adverse events in patients with advanced prostate cancer treated with apalutamide: A pooled analysis of TITAN and SPARTAN." Journal of Clinical Oncology 43, no. 5_suppl (2025): 137. https://doi.org/10.1200/jco.2025.43.5_suppl.137.

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137 Background: The impact of statins on overall survival (OS) in patients (pts) with advanced prostate cancer is not fully understood. We performed a pooled analysis of the TITAN and SPARTAN trials to determine if exposure to statins had an independent effect on OS and grade ≥3 cardiac adverse events (AE) in pts treated with androgen deprivation therapy (ADT) with/without apalutamide (APA). Methods: TITAN and SPARTAN randomized pts to receive ADT with/without APA either in metastatic hormone-sensitive or in non-metastatic castration-resistant prostate cancer, respectively. Pts had at least so
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Small, Eric Jay, Kim N. Chi, Simon Chowdhury, et al. "Association between patient-reported outcomes (PROs) and changes in prostate-specific antigen (PSA) in patients (pts) with advanced prostate cancer treated with apalutamide (APA) in the SPARTAN and TITAN studies." Journal of Clinical Oncology 40, no. 6_suppl (2022): 73. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.073.

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73 Background: In phase 3 placebo (PBO)-controlled studies, addition of APA to androgen deprivation therapy (ADT) improved overall survival, resulted in rapid and deep PSA declines, and reduced risk of disease progression while preserving health-related quality of life (HRQoL) in nonmetastatic castration-resistant prostate cancer (nmCRPC; SPARTAN) and metastatic castration-sensitive prostate cancer (mCSPC; TITAN). This post hoc analysis evaluated the association of a deep PSA decline with PROs in these studies. Methods: Pts on ADT were randomized to APA (240 mg QD) or PBO: SPARTAN 2:1 (N = 1,2
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Johnson, Dennis A. "Stability of Slow-Rusting Resistance to Puccinia asparagi and Managing Rust in Asparagus." Plant Disease 96, no. 7 (2012): 997–1000. http://dx.doi.org/10.1094/pdis-09-11-0797-re.

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The stability of slow-rusting resistance to Puccinia asparagi in several asparagus cultivars was evaluated in two replicated field trials. Rust epidemics were monitored in each trial for 8 years spanning a period of 13 years (1983–1990 and 1987–1995). Inoculum of P. asparagi, an autoecious macrocyclic rust, originated each year as teliospores. In the first trial, the cultivars Jersey Titan, Jersey Centennial, Jersey Giant, Delmonte-361, and UC-157 had consistently lower area under the disease progress curve (AUDPC) values than Wash T2 and WSU-1. Cultivar Mary Washington was intermediate betwee
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Chi, Kim N., Fred Saad, Simon Chowdhury, et al. "Prostate-specific antigen (PSA) kinetics in patients (pts) with advanced prostate cancer treated with apalutamide: Results from the TITAN and SPARTAN studies." Journal of Clinical Oncology 38, no. 15_suppl (2020): 5541. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.5541.

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5541 Background: The phase III TITAN and SPARTAN studies demonstrated improved outcomes with the addition of apalutamide (APA) to androgen deprivation therapy (ADT); outcomes included prolonging overall survival and radiographic progression-free survival (rPFS) in metastatic castration-sensitive prostate cancer (mCSPC) in TITAN, and metastasis-free survival (MFS) in nonmetastatic castration-resistant PC (nmCRPC) in SPARTAN. A post hoc analysis of PSA kinetics in pts from both studies is reported. Methods: Baseline PSA at randomization, time to PSA nadir, and proportion of pts achieving a PSA d
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Greenhalgh, Janette, Adrian Bagust, Angela Boland, et al. "Erlotinib and gefitinib for treating non-small cell lung cancer that has progressed following prior chemotherapy (review of NICE technology appraisals 162 and 175): a systematic review and economic evaluation." Health Technology Assessment 19, no. 47 (2015): 1–134. http://dx.doi.org/10.3310/hta19470.

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BackgroundLung cancer is the second most diagnosed cancer in the UK. Over 70% of lung cancers are non-small cell lung cancers (NSCLCs). Patients with stage III or IV NSCLC may be offered treatment to improve survival, disease control and quality of life. One-third of these patients receive further treatment following disease progression; these treatments are the focus of this systematic review.ObjectivesTo appraise the clinical effectiveness and cost-effectiveness of erlotinib [Tarceva®, Roche (UK) Ltd] and gefitinib (IRESSA®, AstraZeneca) compared with each other, docetaxel or best supportive
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Calvez, V., AM Hill, and AG Marcelin. "Re-evaluation of resistance algorithms for lopinavir/ritonavir in the TITAN trial." Journal of the International AIDS Society 11, Suppl 1 (2008): P178. http://dx.doi.org/10.1186/1758-2652-11-s1-p178.

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Đorđević, Mića, Dragan Đorđević, Vladimir Đorđević, and Nenad Gačić. "Manufacture of the reactor for chlorine-dioxide production from double-layer titanium-steel plates." Zavarivanje i zavarene konstrukcije 69, no. 3 (2024): 129–41. http://dx.doi.org/10.5937/zzk2403129q.

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Titanium has the widest application of all reactive metals. The basic properties of titanium are good corrosion resistance and an excellent strength-to-weight ratio. It is applied in: chemical industry, aviation, rocket technology, medicine, etc. With development of metallurgy of titanium production, its price became much more accessible, but it is still very high, the welding repair is therefore applied wherever possible. Welding is also significantly used for the production of machine parts. This paper presents a detailed procedure of reactor vessel production for obtaining chlorinedioxide (
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Dissertations / Theses on the topic "TITAN trial"

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Ni, Xinghua. "Late Paleozoic - Early Mesozoic tectonic evolution of the southwestern Central Asian Orogenic Belt : structural, metamorphic and magmatic evidence from the eastern Tianshan." Electronic Thesis or Diss., Orléans, 2024. http://www.theses.fr/2024ORLE1043.

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Les orogènes d'accrétion formées le long de marges convergentes se caractérisent par une longue évolution et sont les principaux sites de croissance continentale sur la Terre. Les phénomènes de convergence dans les orogènes d'accrétion impliquent des processus tectoniques complexes, tels que la subduction et le retrait de slabs, l'accrétion arc-arc/continent, et l'extension post-collisionnelle. Cependant, les processus orogéniques des anciennes orogènes sont plus compliqués en raison de l'importante érosion, nécessitant de connaissances approfondies sur la déformation, le métamorphisme et le m
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HSIUNG, HSU CHI, and 許吉雄. "A Study on The Taipei Tian Mu Hiking Trail Users’ Leisure Benefit and Satisfaction." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/19126625940561355874.

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碩士<br>國立臺北教育大學<br>體育學系碩士班<br>96<br>The purpose of this study was to understand the leisure benefits and satisfaction of Taipei Tian Mu Hiking Trail Users’, also to analyze the difference in degree of leisure benefit and satisfaction of this Hiking Trail according to different demographic variables. The survey started on Jan.21 and ended on Feb. 10, 2008. The “Questionnaire of Taipei Tian Mu Hiking Trail Users’ Leisure Benefit and Satisfaction” was used for this purpose. Of all the received questionnaires, 355 were valid. According to the data and descriptive statistics, data analysis was accom
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Chuang, Hui-Wen, and 莊惠雯. "A Study of the Writers from Other Provinces:The Tribal Identification of the First and Second Generations---Case Studies:Zhu Xi-Ning,Zhu Tian-Wen,and Zhu Tian-Xin." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/dt9jf9.

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Books on the topic "TITAN trial"

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The Philadelphia Titan The Adam Renfroe Jr. Story: Lawyer Who Put Major League Baseball on Trial. Page Publishing, Inc, 2019.

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Lobdell, Scott. Teen Titans: The trial of Kid Flash. 2015.

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Awo, on the trail of a titan: Essays in celebration of the Obafemi Awolowo centennial. The Obafemi Awolowo Foundation, 2009.

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Conference papers on the topic "TITAN trial"

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Rocha, George, and Rainer Kurz. "Field and Application Experience of the Titan 130 Industrial Gas Turbine." In ASME Turbo Expo 2001: Power for Land, Sea, and Air. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/2001-gt-0224.

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The two-shaft Titan 130 industrial gas turbine was introduced into commercial service in 1998 and has gained field experience in mechanical-drive and compressor-set applications. A single-shaft configuration is also available for electrical power generation applications. The 14-MW class two-shaft engine is nominally rated at 19,500 hp with a simple-cycle efficiency of more than 35% at ISO operating conditions. It is available with two combustor options: a dry, low-pollutant emissions combustion system featuring Solar’s proven SoLoNOx technology or a diffusion-flame type combustor adapted from
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Wiest, I., R. Keller, M. Marin-Galiano, et al. "Steroid and antibiotic treatment are associated with diverse immunotherapy efficacy a pooled analysis of the RAMONA, INTEGA, OPTIM, ELDORANDO, FORCE, TITAN-RCC and TITAN-TCC trials of the German AIO study group." In Viszeralmedizin 2024. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1789880.

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Yuan, Shuai, Fujian Zhou, Yakai Tian, Tianbo Liang, and Xingyuan Liang. "Laboratory Evaluation of Micro-Proppants on Enhancement of Microfracture Conductivity." In 56th U.S. Rock Mechanics/Geomechanics Symposium. ARMA, 2022. http://dx.doi.org/10.56952/arma-2022-2055.

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ABSTRACT: The complex fracture network generated from hydraulic fracturing is of great importance for well productivity in unconventional reservoirs. However, numerous natural or induced microfractures are closed without proppant placement after hydraulic fracturing is completed. Micro-proppants have small enough particle sizes and longer transport distances, which can access microfractures and keep them open. The objective of this work is to investigate the particle size distribution, crushing rate as well as microfracture conductivity by micro-proppants from fly ash. Microproppants have a la
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Reports on the topic "TITAN trial"

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Cowell, Luke, and Ivan Carlos. PR-283-18202-R01 Improved SoLoNox T70S and T130S Controls to Reduce Part Load Emissions. Pipeline Research Council International, Inc. (PRCI), 2021. http://dx.doi.org/10.55274/r0012019.

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An executed NDA is required from Solar Turbines to have access to this document. The low load control algorithm for Solar Turbines' Taurus 70-10802S and Titan 130-20502S has been modified and evaluated in two field trials at the Kinder Morgan Wharton 301 and Enbridge Sabal Trail Alexander City Compressor Stations. The new algorithm extends temperature control, via bleed valve modulation, to lower engine speed settings now covering operation from full load to idle vs full load to 50% load with the prior production control method. The pilot fuel control schedule has also been optimized along wit
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Tian, Cong, Jianlong Shu, Wenhui Shao, Zhengxin Zhou, Huayang Guo та Jingang Wang. The efficacy and safety of IL Inhibitors, TNF-α Inhibitors, and JAK Inhibitor on ankylosing spondylitis: A Bayesian network meta-analysis of a “randomized, double-blind, placebo-controlled” trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.9.0117.

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Review question / Objective: In this study, we conducted a Bayesian network meta-analysis to evaluate the efficacy and safety of interleukin (IL) inhibitors, tumor necrosis factor-alpha (TNF-α) inhibitors, and Janus kinase (JAK) inhibitors on ankylosing spondylitis (AS).The purpose of this study is to compare the effectiveness and safety of different interventions for treating AS to provide insights into the decision-making in clinicalpractice. Condition being studied: Ankylosing spondylitis. Based on the Bayesian hierarchical model, we conducted a network meta-analysis using the gemtc package
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