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Journal articles on the topic 'TMAPS'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Kalifa, Abdarahman M., Iwan Triyuwono, Gugus Irianto, and Yeney Widya Prihatiningtias. "The use and benefit of management accounting practices in Libyan oil companies." Asian Journal of Accounting Research 5, no. 1 (March 13, 2020): 91–102. http://dx.doi.org/10.1108/ajar-08-2019-0066.

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PurposeThe purpose of this study is to describe the use and benefit of TMAPs and CMAPs in Libyan oil companies.Design/methodology/approachThe data were collected by distributing 210 mailed questionnaires to senior financial staff, such as financial managers, heads of cost department, financial accountants, department of management accounting employees, managerial accountants and Auditors. IFAC-based model was used in analyzing evolution stages in Libyan management accounting practices.FindingsThis study finds that Libyan oil companies use CMAPs more than TMAPs, the latter being commonly used in Libyan manufacturing companies. This study also finds that CMAPs are more beneficial than TMAPs.Practical implicationsThis study provides more understanding of the use and the benefit of TMAPs and CMAPs and fills research gap regarding the matter, as well as provides new findings that can be used for further research regarding the use and benefit of TMAPs and CMAPs for Libyan oil companies.Originality/valueThe results contribute to a better understanding concerning the use and benefit of TMAPs and CMAPs in Libyan oil companies.

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2

Hussein, Amani. "Adoption, Importance and Barriers to the Implementation of Contemporary Management Accounting Practices: Evidence from Egypt." Accounting and Finance Research 7, no. 1 (December 20, 2017): 192. http://dx.doi.org/10.5430/afr.v7n1p192.

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Nowadays, complexity in the business environment, and advanced technology intensified the challenges for more management accounting information to meet global competition. Therefore, contemporary management accounting practices have emerged which focused on financial and non-financial information to support managers’ decision making. The research aimed at examining the adoption, importance and barriers to the implementation of CMAPs. To achieve the research aim a list of forty MAPs, 171 questionnaires and factor analysis were used. In terms of MAPs adoption the results indicated 9 factors :fundamental TMAPs; control; WCM; performance evaluation non-financial; budgeting for planning cash flows ;contemporary decision support; traditional decision support; planning and capital budget practice. In terms of importance there are 10 factors; benchmarking practices; costing and decision support; fundamental TMAPs; traditional performance evaluation; control; contemporary performance evaluation; budget for planning day to day; WCM –MRP practice, product life cycle practice and performance evaluation – customer satisfaction. The main conclusion was the relative adoption of TMAPs are higher than CMAPs however, the Egyptian companies are realizing the importance of large number of CMAPs. Moreover, the research examined barriers that could limit the implementation of CMAPs and revealed that the highest barriers were; it takes longer time to change the societal values and practices, high degree of uncertainty avoidance and high cost to implement these advanced practices respectively.

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3

Krisztin, Tibor. "Invariance and Noninvariance of Center Manifolds of Time-tMaps with Respect to the Semiflow." SIAM Journal on Mathematical Analysis 36, no. 3 (January 2005): 717–39. http://dx.doi.org/10.1137/s0036141003419170.

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4

Wu, Kuo-Hui, Yin-Chiung Chang, Ken-Fa Cheng, and Je-Chuang Wang. "Antibacterial Activity of Surface-Modified Fabric with Ag/AgCl-Doped Quaternary Ammonium-Modified Silicate Hybrid." Journal of Nanoscience and Nanotechnology 19, no. 11 (November 1, 2019): 7285–93. http://dx.doi.org/10.1166/jnn.2019.16634.

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An organic–inorganic hybrid antibacterial material based on Ag/AgCl and quaternary ammoniummodified silicate (Ormosil (NR+4 Cl-)) was prepared by sol–gel processes and an in situ reduction method, in which silver nitrate, tetraethoxysilane (TEOS), N-trimethoxysilylpropyl-N,N,Ntrimethylammonium chloride (TMAPS) and N-[3-(trimethoxysilyl)propyl]diethylenetriamine (ATS) acted as precursor, linker and colloidal suspension stabilizer, respectively. The physical properties of the Ormosil (NR+4 Cl-) and Ormosil (NR+4 Cl-)/Ag hybrids were examined using XPS and TGA spectroscopy, the results of which indicated that Ag/AgCl was immobilized in channels by dipolar interactions with the Ormosil (NR+4 Cl-) matrix. Ormosil (NR+4 Cl-) and Ormosil (NR+4 Cl-)/Ag sol solutions were used to functionalize non-woven fabrics by simply immersing the textiles into the dispersions in order to obtain antimicrobial fabrics. The antibacterial effects of the Ormosil/Ag- and Ormosil (NR+4 Cl-)/Ag-modified fabrics against Gram-negative P. aeruginosa and E. coli, and Grampositive S. aureus and B. subtilis, were assessed using the zone of inhibition and the plate-counting method. The antibacterial efficacy was maintained even after 20 laundry cycles. The results indicated that the Ormosil/Ag and Ormosil (NR+4 Cl-)/Ag hybrids are useful as non-leaching agents imparting durable antimicrobial properties to fabrics.

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5

Blackman, Ross, Matthew Legge, and Ashim Kumar Debnath. "Comparison of Three Traffic Management Plans Showing Shadow and Police Vehicle Effects on Driver Behavior at Highway Single Lane Closures." Transportation Research Record: Journal of the Transportation Research Board 2674, no. 9 (July 19, 2020): 15–25. http://dx.doi.org/10.1177/0361198120925473.

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Lane closures on multi-lane roads require drivers to transition safely to an open lane before passing the worksite. To reduce worker and driver injury risk, truck-mounted attenuators (TMAs) are often used to prevent vehicle work zone intrusions and reduce the severity of collisions. To maximize the efficiency and effectiveness of TMA use, it is necessary to determine how and when they should be deployed as well as the best supporting measures. The current research focuses on the effects of different traffic management plans (TMPs) on driver behavior. Three TMPs at night time highway work zones were examined: ( 1 ) two tail vehicles in the advance warning area, ( 2 ) three tail vehicles in the advance warning area, and ( 3 ) addition of a marked police car with flashing lights in the buffer area downstream of the TMA. Driver response to the different TMPs was assessed by measuring vehicle speeds at three points in the traffic management area and observing lane change and merging behaviors on the approach to the TMA. Analysis showed a positive effect of police presence in the buffer area on driver behavior: TMP3 produced a reduction of 8.4%–12.9% in proportions of vehicles exceeding the speed limit by at least 5 km/h when passing the TMA. TMP3 also appeared to produce a positive effect on merging behavior compared with the other layouts. Use of a third tail vehicle in the advance warning area was not found to produce any additional safety benefit and may have a detrimental effect.

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6

Ghaderi, Masoumeh, S. Zahra Bathaie, Ali-Akbar Saboury, Hashem Sharghi, and Shahram Tangestaninejad. "Interaction of an Fe derivative of TMAP (Fe(TMAP)OAc) with DNA in comparison with free-base TMAP." International Journal of Biological Macromolecules 41, no. 2 (July 2007): 173–79. http://dx.doi.org/10.1016/j.ijbiomac.2007.01.014.

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7

Biwersi, Joachim, Nazih Farah, Yong-Xiong Wang, R. Ketcham, and A. S. Verkman. "Synthesis of cell-impermeable Cl-sensitive fluorescent indicators with improved sensitivity and optical properties." American Journal of Physiology-Cell Physiology 262, no. 1 (January 1, 1992): C243—C250. http://dx.doi.org/10.1152/ajpcell.1992.262.1.c243.

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Quinolinium compounds have been used as Cl-sensitive fluorescent indicators in cells and cell-free membrane fractions. To improve Cl sensitivity and for conjugation via nucleophilic reaction, the compounds 6-methoxy-N-(n-aminoalkyl)quinolinium bromide hydrochloride (AAQ) with alkyl chain lengths (n) of 2 (AEQ), 3 (APQ), and 4 (ABQ) were synthesized. AAQ was water soluble, fluorescent, and quenched by Cl. The Stern-Volmer constants (KCl) for quenching of protonated AEQ, APQ and ABQ by Cl were 354, 322, and 272 M-1, respectively, higher than KCl for 6-methoxy-N-(3-sulfopropyl)quinolinium (SPQ; 118 M-1). To eliminate pH-dependent fluorescence, 6-methoxy-N-(3-trimethylammoniumpropyl)quinolinium dibromide (TMAPQ) was synthesized (KCl, 310 M-1). To red shift fluorescence excitation and emission spectra, 6-phenyl-N-(3-trimethylammoniumpropyl) quinolinium dibromide (phenyl-TMAPQ) (emission 475 nm) and N-(3-trimethylammoniumpropyl)phenanthridinium dibromide (TMAPP) (excitation 380 nm) were synthesized. AEQ and ABQ were conjugated with neutral dextran activated by cyanogen bromide to give indicator-to-dextran mole ratios of 5 to 20. KCl values at pH 7.4 were 132 (AEQ-dextran) and 237 M-1 (ABQ-dextran). To construct a single molecule with Cl-sensitive and insensitive moieties, the bichromophores 6-methoxy-N-(n-dansylsulfonamidoalkyl)quinolinium with alkyl chains of two and four were synthesized. The new Cl-sensitive indicators were used for measurement of intracellular Cl activity and for the labeling of endocytic vesicles in 3T3 fibroblasts and T84 cells. Our results indicate that N-substitution of quinoline with positively charged moieties gives increased Cl sensitivity, and extension of ring conjugation gives indicators with red-shifted fluorescence spectra. 6-methoxy-N-(3-sulfopropyl)quinolinium; dextran; fibroblast Submitted on December 20, 1990 Accepted on June 10, 1991

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8

Miele, Joshua A., Steven Landau, and Deborah Gilden. "Talking TMAP: Automated generation of audio-tactile maps using Smith-Kettlewell's TMAP software." British Journal of Visual Impairment 24, no. 2 (May 2006): 93–100. http://dx.doi.org/10.1177/0264619606064436.

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9

Im, Cheol, and Sung Tae Ku. "A Study on the Implementation of TMAP for MCRS Automatic Processing System Based on MES." Journal of the Korea Management Engineers Society 25, no. 2 (June 30, 2020): 187–205. http://dx.doi.org/10.35373/kmes.25.2.11.

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10

Stock, Martin. "TMAP Wadden Sea Sedimentation Database." Biodiversity & Ecology 4 (September 10, 2012): 372. http://dx.doi.org/10.7809/b-e.00162.

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11

Stock, Martin. "TMAP Wadden Sea Vegetation Database." Biodiversity & Ecology 4 (September 10, 2012): 373. http://dx.doi.org/10.7809/b-e.00163.

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12

PARKMAN, CYNTHIA A., KAY J. EVANS, and ROSIE COX. "Mapping out care with TMAP." Nursing 30, no. 8 (August 2000): 74. http://dx.doi.org/10.1097/00152193-200030080-00034.

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13

Wang, Yue, Danqun Huo, Huixiang Wu, Hui Liu, Junjie Li, Mei Yang, Chenghong Huang, and Changjun Hou. "A Ratiometric Fluorescent Assay for Fluazinam Based on FRET Between CdTe Quantum Dots and Porphyrin." Nano 12, no. 10 (October 2017): 1750128. http://dx.doi.org/10.1142/s1793292017501284.

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A fluorescent detection system for fluazinam was reported using fluorescence resonance energy transfer (FRET) method based on CdTe quantum dots (CdTe QDs) and 5, 10, 15, 20-tetrakis(4-methacryloyloxy) phenyl porphyrin (TMaPP). TMaPP and water-soluble CdTe QDs were synthesized successfully and characterized using FT-IR, 1H NMR, XPS and TEM, respectively. FRET mechanism between CdTe QDs and TMaPP was confirmed by detailed studies on their fluorescent spectra. After a co-culture of TMaPP and CdTe QDs, fluorescent intensity of CdTe QDs decreased significantly while that of TMaPP increased concomitantly due to altered FRET. Addition of fluazinam led to impaired energy transfer from CdTe QDs to TMaPP and therefore fluorescence recovery of CdTe QDs with fluorescence quenching of TMaPP. The correlation of fluazinam concentration with the fluorescence intensity ratio [Formula: see text] provided the basis for quantitative analysis, and a broad linear range varying from 0.01[Formula: see text][Formula: see text]M to 5[Formula: see text][Formula: see text]M with a low detection limit of 2.3[Formula: see text]nM was obtained. As-reported sensor system demonstrated excellent reproducibility, selectivity and sensitivity in real sample detection.

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14

Topayung, Daud. "PENGARUH ARUS LISTRIK DAN WAKTU PROSES TERHADAP KETEBALAN DAN MASSA LAPISAN YANG TERBENTUK PADA PROSES ELEKTROPLATING PELAT BAJA." JURNAL ILMIAH SAINS 11, no. 1 (April 1, 2011): 97. http://dx.doi.org/10.35799/jis.11.1.2011.50.

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Penelitian menggunakan hukum Faraday untuk analisis teoritis dan metode statistik untuk analisis hasil pengukuran. Hasil teoritis, Ketebalan: Tmaks = 0.116461 mm, Tmin = 0.028423 mm. Massa: Mmaks = 5.2100 gr, Mmin = 1.3025 gr. Hasil pengukuran, Ketebalan: Tmaks = 0.109 mm, Tmin = 0.026 mm. Massa: Mmaks = 4.8516 gr, Mmin = 1.1902 gr. Ketebalan dan massa lapisan teoritis lebih besar dari hasil pengukuran. Perbedaan keduanya: Tmaks = 0.007 mm (6.12%), Tmin = 0.002 mm (7.35%), Mmaks = 0.3564 gr (6.88%), Mmin = 0.1123 gr (8.62%). Untuk hasil teoritis dan hasil pengukuran: Tmaks and Mmaks diperoleh pada arus listrik = 8 Ampere dan waktu proses 60 menit, Tmin dan Mmin diperoleh pada arus listrik = 4 Ampere dan waktu proses 30 menit. EFFECT OF ELECTRIC CURRENT AND PROCESS TIME THE THICKNESS AND MASS LAYER FORMED ON ELECTROPLATING PROCESSSTEEL PLATESABSTRACTResearch using Faraday's law for the theoretical analysis and statistical methods to analyze the results of measurements. Theoretical results, Thickness: Tmaks = 0.116461 mm, Tmin = 0.028423 mm. Mass: Mmaks = 5.2100 gr, Mmin = 1.3025 gr. Results of measurement, Thickness: Tmaks = 0.109 mm, Tmin = 0.026 mm. Mass: Mmaks = 4.8516 gr, Mmin = 1.1902 gr. Layer thickness and mass is theoretically greater than the measurement results. Differences both: Tmaks = 0.007 mm (6.12%), Tmin = 0.002 mm (7.35%), Mmaks = 0.3564 gr (6.88%), Mmin = 0.1123 gr (8.62%). For the theoretical results and measurements: Tmaks and Mmaks obtained at an electric current = 8 Amperes and 60 minutes, Tmin and Mmin obtained = 4 Amperes of electric current and 30 minutes

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15

Aditya, Mr Pujari. "Tmap: Traffic Detection using Tweet Analysis." International Journal for Research in Applied Science and Engineering Technology V, no. III (March 30, 2017): 703–6. http://dx.doi.org/10.22214/ijraset.2017.3133.

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16

Brown, John P., and Ashish Chandra. "Science made simple: tissue microarrays (TMAs)." BJU International 114, no. 2 (July 28, 2014): 294–95. http://dx.doi.org/10.1111/bju.12578.

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17

Rosack, Jim. "TMAP Shows Promise In Depression Treatment." Psychiatric News 39, no. 15 (August 6, 2004): 35. http://dx.doi.org/10.1176/pn.39.15.0390035.

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18

Serudji, Joserizal, and Rizanda Machmud. "PERBEDAAN SKOR KECEMASAN TAYLOR MINNESOTA ANXIETY SCALE (TMAS) MATERNAL PADA KEHAMILAN DENGAN PREEKLAMPSIA DAN HAMIL NORMAL." JOURNAL OBGIN EMAS 2, no. 2 (November 28, 2019): 92–100. http://dx.doi.org/10.25077/aoj.2.2.92-100.2018.

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Management of preeclampsia is limited to blood pressure control and symptom relief in combination with close maternal/ fetal surveillance. Until recently, very little attention has been paid to preeclampsia's psychological consequences, especially maternal anxiety. Anxiety disorders can be identified using questionnaires instrument determining anxiety level, the Taylor Minnesota Anxiety Scale (TMAS) questionnaires is one among them. This study aimed to determine the TMAS maternal anxiety score difference between preeclampsia and normal pregnancy. This was an analytical study with a cross-sectional design conducted from March-August 2014 in 40 subjects, consisting of 20 women with preeclampsia and 20 women with normal pregnancy who met the inclusion and exclusion criteria. Anxiety was measured with the TMAS questionnaire. Statistical analysis to determine the TMAS maternal anxiety score difference between preeclampsia and normal pregnancy was t-test. In preeclampsia group, the mean of TMAS maternal anxiety score was 30,45 ± 9,65. While in the normal pregnancy group, the mean of TMAS maternal anxiety score was 18,50 ± 7,62. There was a significant TMAS maternal anxiety score difference between preeclampsia and normal pregnancy (p = 0,000).Keywords: TMAS maternal anxiety score, preeclampsia

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19

Amiri, Nesrine, Mouhieddinne Guergueb, Maged S. Al-Fakeh, Marwa Bourguiba, and Habib Nasri. "A new cobalt(ii) meso-porphyrin: synthesis, characterization, electric properties and application in the catalytic degradation of dyes." RSC Advances 10, no. 73 (2020): 44920–32. http://dx.doi.org/10.1039/d0ra08786f.

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In this work, a new porphyrin, 5,10,15,20-tetrakis{4-[((4-methoxyphenyl)acetyl)oxy]phenyl}porphyrin (H₂TMAPP) (1), and its cobalt complex [Co^II(TMAPP)] (2) were synthesized in good and quantitative yields, respectively.

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20

Tomio, Ryosuke, Takenori Akiyama, Takayuki Ohira, and Kazunari Yoshida. "Effects of transcranial stimulating electrode montages over the head for lower-extremity transcranial motor evoked potential monitoring." Journal of Neurosurgery 126, no. 6 (September 2016): 1951–58. http://dx.doi.org/10.3171/2016.7.jns16643.

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OBJECTIVEThe aim of this study was to determine the most effective electrode montage to elicit lower-extremity transcranial motor evoked potentials (LE-tMEPs) using a minimum stimulation current.METHODSA realistic 3D head model was created from T1-weighted images. Finite element methods were used to visualize the electric field in the brain, which was generated by transcranial electrical stimulation via 4 electrode montage models. The stimulation threshold level of LE-tMEPs in 52 patients was also studied in a practical clinical setting to determine the effects of each electrode montage.RESULTSThe electric field in the brain radially diffused from the brain surface at a maximum just below the electrodes in the finite element models. The Cz-inion electrode montage generated a centrally distributed high electric field with a current direction longitudinal and parallel to most of the pyramidal tract fibers of the lower extremity. These features seemed to be effective in igniting LE-tMEPs.Threshold level recordings of LE-tMEPs revealed that the Cz-inion electrode montage had a lower threshold on average than the C3–C4 montage, 76.5 ± 20.6 mA and 86.2 ± 20.6 mA, respectively (31 patients, t = 4.045, p < 0.001, paired t-test). In 23 (74.2%) of 31 cases, the Cz-inion montage could elicit LE-tMEPs at a lower threshold than C3–C4.CONCLUSIONSThe C3–C4 and C1–C2 electrode montages are the standard for tMEP monitoring in neurosurgery, but the Cz-inion montage showed lower thresholds for the generation of LE-tMEPs. The Cz-inion electrode montage should be a good alternative for LE-tMEP monitoring when the C3–C4 has trouble igniting LE-tMEPs.

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21

Mazo, Giovana Zarpellon, Eduardo Capeletto, Keyla Mara Santos, Franciele Silva Pereira, Enaiane Cristina Menezes, and Janeisa Franck Virtuoso. "Motivos de aderência das idosas incontinentes após follow-up de 24 meses de treinamento muscular." Motricidade 14, SI (December 30, 2018): 11–15. http://dx.doi.org/10.6063/motricidade.16228.

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Objetivo: investigar os motivos de aderência 24 meses após intervenção com treinamento dos musculos do assoalho pélvico (TMAP) com e sem musculação em idosas com incontinência urinária (IU). Método: Após o follow-up de 24 meses das intervenções foram contatadas 23 idosas. Foram aplicados o International Consultation on Incontinence Questionnaire – Short Form(ICIQ-SF) para verificar a frequência e gravidade da IU e o Questionário de Motivos para a Prática do TMAP para descrever os motivos de aderência ao TMAP e a prática de exercícios físicos (AFR). Resultados: Após 24 meses do tratamento da IU por meio do TMAP com e sem a prática da musculação 30,4% (n=7) das idosas permaneceram continentes. A adesão ao TMAP foi de 52,2% (n=12) e ao AFR de 73,9% (n=17), após 24 meses da intervenção. O motivo para a prática do TMAP foi a prevenção da IU. Para a AFR, o principal motivo foi a melhora da saúde geral. Conclusão: Sugerem-se novos estudos que utilizem estratégias para facilitar a adesão ao tratamento, num período longo de seguimento

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22

Jaodand, Amruta, Jason W. T. Hessels, and Anne Archibald. "A decade of transitional millisecond pulsars." Proceedings of the International Astronomical Union 13, S337 (September 2017): 47–51. http://dx.doi.org/10.1017/s1743921317010407.

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AbstractTransitional millisecond pulsars (tMSPs), which are systems that harbor a pulsar in the throes of the recycling process, have emerged as a new source class since the discovery of the first such system a decade ago. These systems switch between accretion-powered low-mass X-ray binary (LMXB) and rotation-powered radio millisecond pulsar (RMSP) states, and provide exciting avenues to understand the physical processes that spin-up neutron stars to millisecond periods. During the last decade, three tMSPs, as well as a candidate source, have been extensively probed using systematic, multi-wavelength campaigns. Here we review the observational highlights from these campaigns and our general understanding of tMSPs.

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23

Gallo, Anthony A., Lance E. Dougald, and Michael J. Demetsky. "Formalized Process for Performance Assessment of Work Zone Transportation Management Plans in Virginia." Transportation Research Record: Journal of the Transportation Research Board 2337, no. 1 (January 2013): 50–58. http://dx.doi.org/10.3141/2337-07.

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FHWA's Final Rule on Work Zone Safety and Mobility, which is part of the Code of Federal Regulations, requires transportation management plans (TMPs) for all federally funded roadway construction projects. These plans are a documented combination of traffic control, public relations, and transportation demand operations strategies designed to mitigate the impacts that work zones can have on safety and mobility. A key component in TMPs is monitoring and assessing traffic impacts to incorporate lessons learned into future TMPs. The Virginia Department of Transportation (DOT) sought to formalize a process to assess individual TMPs and TMPs at an agencywide level. This paper summarizes the rationale and steps taken to develop this TMP assessment process. This process, which has been developed in the form of Virginia DOT's new TMP performance assessment guidelines and postconstruction report form, is outlined for various project complexities.

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24

Shechter, Dvir, Michal Harel, Abhishek Mukherjee, Leonel M. Sagredo, David Loven, Elad Prinz, Shimrit Avraham, et al. "Breast Cancer-Derived Microparticles Reduce Cancer Cell Adhesion, an Effect Augmented by Chemotherapy." Cells 9, no. 10 (October 10, 2020): 2269. http://dx.doi.org/10.3390/cells9102269.

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Tumor cell heterogeneity is primarily dictated by mutational changes, sometimes leading to clones that undergo a metastatic switch. However, little is known about tumor heterogeneity following chemotherapy perturbation. Here we studied the possible involvement of tumor-derived extracellular vesicles, often referred to as tumor-derived microparticles (TMPs), as mediators of the metastatic switch in the tumor microenvironment by hindering cell adhesion properties. Specifically, we show that highly metastatic or chemotherapy-treated breast cancer cells shed an increased number of TMPs compared to their respective controls. We found that these TMPs substantially reduce cell adhesion and disrupt actin filament structure, therefore increasing their biomechanical force pace, further implicating tumor cell dissemination as part of the metastatic cascade. Our results demonstrate that these pro-metastatic effects are mediated in part by CD44 which is highly expressed in TMPs obtained from highly metastatic cells or cells exposed to chemotherapy when compared to cells with low metastatic potential. Consequently, when we inhibited CD44 expression on TMPs by a pharmacological or a genetic approach, increased tumor cell adhesion and re-organized actin filament structure were observed. We also demonstrated that breast cancer patients treated with paclitaxel chemotherapy exhibited increased CD44-expressing TMPs. Overall, our study provides further insights into the role of TMPs in promoting metastasis, an effect which is augmented when tumor cells are exposed to chemotherapy.

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Longhurst, Glen R., and James Ambrosek. "Verification and Validation of the Tritium Transport Code TMAP7." Fusion Science and Technology 48, no. 1 (August 2005): 468–71. http://dx.doi.org/10.13182/fst05-a967.

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26

Hong, Kyung Uk, Young Soo Park, Yeon-Sun Seong, Dongmin Kang, Chang-Dae Bae, and Joobae Park. "Functional Importance of the Anaphase-Promoting Complex-Cdh1-Mediated Degradation of TMAP/CKAP2 in Regulation of Spindle Function and Cytokinesis." Molecular and Cellular Biology 27, no. 10 (March 5, 2007): 3667–81. http://dx.doi.org/10.1128/mcb.01386-06.

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ABSTRACT Cytoskeleton-associated protein 2 (CKAP2), also known as tumor-associated microtubule-associated protein (TMAP), is a novel microtubule-associated protein that is frequently upregulated in various malignances. However, its cellular functions remain unknown. A previous study has shown that its protein level begins to increase during G1/S and peaks at G2/M, after which it decreases abruptly. Ectopic overexpression of TMAP/CKAP2 induced microtubule bundling related to increased microtubule stability. TMAP/CKAP2 overexpression also resulted in cell cycle arrest during mitosis due to a defect in centrosome separation and subsequent formation of a monopolar spindle. We also show that degradation of TMAP/CKAP2 during mitotic exit is mediated by the anaphase-promoting complex bound to Cdh1 and that the KEN box motif near the N terminus is necessary for its destruction. Compared to the wild type, expression of a nondegradable mutant of TMAP/CKAP2 significantly increased the occurrence of spindle defects and cytokinesis failure. These results suggest that TMAP/CKAP2 plays a role in the assembly and maintenance of mitotic spindles, presumably by regulating microtubule dynamics, and its destruction during mitotic exit serves an important role in the completion of cytokinesis and in the maintenance of spindle bipolarity in the next mitosis.

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Davila, Monica, Ali Amirkhosravi, Enriqueta Coll, Robles D. Liza, and John Francis. "Tissue Factor-Bearing Microparticles Derived from Tumor Cells: Impact on Coagulation Activation." Blood 108, no. 11 (November 16, 2006): 1757. http://dx.doi.org/10.1182/blood.v108.11.1757.1757.

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Abstract Thromboembolic disease is a frequent complication in cancer. Tissue factor (TF), shown to be involved in tumor growth and metastasis, is also considered to play a central role in the pathogenesis of cancer-associated thrombosis. Circulating TF-bearing microparticles (TF+ MPs) have been found in the plasma of patients with different malignancies and are thought to contribute to their hypercoagulable state. Although numerous studies have focused on TF+ MPs derived from blood cells, there is no information available on the pathological relevance of MPs originating from tumor cells. We conducted a study to detect, enumerate and characterize the procoagulant activity (PCA) of MPs released specifically from tumor cells. MPs from high (MDA-231) and low (MCF-7) TF-expressing human breast carcinoma cells were generated ex vivo in whole blood or in buffer under stirring conditions for 45 minutes. The numbers (MPs/ml) of total and TF-expressing tumor-derived particles (TMPs) in cell-free plasmas were measured by flow cytometry using FITC-labeled annexin V and a PE-labeled monoclonal anti-TF antibody respectively. The PCA of TMPs was measured by a one stage clotting assay and a highly sensitive fluorogenic thrombin generation assay. In order to evaluate the PCA of circulating TMPs, we injected 2x106 TF+ MPs derived from MDA-231 cells into mice via the tail vein. Human TF antigen and activity were measured in cell-free mouse plasmas at various intervals (5–420 min) after injections by ELISA and clotting assay, respectively. MPs less than 1μm in diameter were released from tumor cells in both buffer and whole blood by stirring. TMPs positive for TF consisted of approximately 40% of the annexin V+ MPs, and such particles derived from as low as 1x105 MDA-231 cells could be enumerated reliably (2.5x104 MPs/105 cells). By ultracentrifugation of cell-free plasmas, we confirmed that TF antigen was associated entirely with the MP fraction. TMPs derived from as few as 450 MDA-231 cells shortened plasma recalcification times from 525 ± 114 to 265 ± 148 (P<0.01), and significantly accelerated thrombin generation as evidenced by a 3 fold shortening in lag time, and a 2 fold increase in the rate of thrombin formation and thrombin concentration. No PCA was detected with MCF-7-derived TMPs. The PCA of TMPs was inhibited completely by a blocking anti-TF monoclonal antibody, but not by saturating concentrations of annexin V (an inhibitor of phospholipid PCA) or corn trypsin inhibitor (an inhibitor of the intrinsic pathway). Five minutes following the injection of TMPs into mice, appreciable levels of human TF antigen and activity were detected in cell-free plasmas. Both TF activity and antigen decreased over time and were detectable no longer than 30 minutes after injection, indicating a rapid clearance of circulating TMPs in vivo. In contrast, when TMPs were incubated in human whole blood ex vivo for various intervals, TF activity remained unchanged in cell-free plasmas for at least 5 hrs and TF antigen was not detected by flow cytometry on any blood corpuscles, including platelets, at all intervals. However, when whole blood containing TMPs was clotted by recalcification, no TF activity could be detected in the serum, indicating the incorporation of TMPs in formed clots. In summary, MPs bearing active TF are released readily from tumor cells and can significantly activate coagulation even at very low concentrations. These results provide new insights towards the potential contribution of TMPs to the pathogenesis of cancer-associated thrombosis.

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Huang, Haihong, Baosheng Ge, Shuai Zhang, Jiqiang Li, Chenghao Sun, Tongtao Yue, and Fang Huang. "Using Fluorescence Quenching Titration to Determine the Orientation of a Model Transmembrane Protein in Mimic Membranes." Materials 12, no. 3 (January 23, 2019): 349. http://dx.doi.org/10.3390/ma12030349.

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After synthesis of transmembrane proteins (TMPs), they are transferred and inserted into plasma membranes to play biological functions. Crucially, orientation of TMPs in membranes determines whether they have biological activities. In cellular environments, a number of cofactors, such as translocon, can assist TMPs to be inserted into membranes in defined orientations. During in vitro reconstitution of TMPs with mimic membranes, both insertion and orientation of TMPs are primarily determined by interactions with the membrane. Yet the knowledge is limited, hindering the in vitro applications of TMPs. Here, we take Bacteriorhodopsin (bR) as a model TMP, using fluorescence quenching titration experiment to identify orientation of bR in mimic membranes, examining effects of a number of factors, including lipid composition, pH value, ionic strength and membrane curvature. The most effective determinant is the lipid type, which modulates insertion and orientation of bR in membranes by changing the membrane surface charge and the membrane fluidity. Both the pH value and the ionic strength play secondary roles by tuning the nature of the electrostatic interaction. The membrane curvature was found to have a minor effect on orientation of bR in membranes. By comparing orientations of bR in folded and unfolded states, no obvious change was observed, informing that nascent proteins could be inserted into membranes in defined orientations before folding into the native state inside the membrane.

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Koroglu, Mehmet, Selami Gunal, Fatma Yildiz, Mehtap Savas, Ali Ozer, and Mustafa Altindis. "Comparison of keypads and touch-screen mobile phones/devices as potential risk for microbial contamination." Journal of Infection in Developing Countries 9, no. 12 (December 30, 2015): 1308–14. http://dx.doi.org/10.3855/jidc.6171.

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Introduction: Touch-screen mobile phones/devices (TMPs/Ds) are increasingly used in hospitals. They may act as a mobile reservoir for microbial pathogens. The rates of microbial contamination of TMPs/Ds and keypad mobile phones (KMPs) with respect to different variables including use by healthcare workers (HCWs)/non-HCWs and the demographic characteristics of users were investigated. Methodology: A total of 205 mobile phones/devices were screened for microbial contamination: 76 devices belonged to HCWs and 129 devices belonged to the non-HCW group. By rubbing swabs to front screen, back, keypad, and metallic surfaces of devices, 444 samples were collected. Results: Of 205 mobile phones/devices, 143 (97.9%) of the TMPs/Ds and 58 (98.3%) of the KMPs were positive for microbial contamination, and there were no significant differences in contamination rates between these groups, although TMPs/Ds had significantly higher microbial load than KMPs (p <0.05). The significant difference in this analysis was attributable to the screen size of mobile phones ≥ 5”. Microbial contamination rates increased significantly as phone size increased (p <0.05). Higher numbers of coagulase-negative Staphylococci (CNS) were isolated from KMPs than TMPs/Ds (p = 0.049). The incidence of Enterococcus spp. was higher on the KMPs of HCWs, and methicillin resistant CNS was higher from the TMPs/Ds of non-HCWs (p <0.05). Isolation of CNS, Streptococcus spp. and Escherichia coli was higher from the TMPs/Ds of HCWs (p <0.05). Conclusions: We found no significant difference between TMP/Ds and KMPs in terms of microbial contamination, but TMP/Ds harboured more colonies and total microbial counts increased with screen size.

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Stegmann, Niklas, Hilke Petersen, Claudia Weidenthaler, and Wolfgang Schmidt. "Facile synthesis of novel, known, and low-valent transition metal phosphates via reductive phosphatization." Journal of Materials Chemistry A 9, no. 34 (2021): 18247–50. http://dx.doi.org/10.1039/d1ta03782j.

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Novel and known low valent transition metal phosphates (TMPs) are accessible via a novel and facile pathway denoted as reductive phosphatization. The method allows syntheses of TMPs especially with reduced oxidation states.

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Rimm, David L., Torsten O. Nielsen, Scott D. Jewell, Daniel C. Rohrer, Gloria Broadwater, Frederic Waldman, Kisha A. Mitchell, et al. "Cancer and Leukemia Group B Pathology Committee Guidelines for Tissue Microarray Construction Representing Multicenter Prospective Clinical Trial Tissues." Journal of Clinical Oncology 29, no. 16 (June 1, 2011): 2282–90. http://dx.doi.org/10.1200/jco.2010.33.2023.

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Practice-changing evidence requires confirmation, preferably in multi-institutional clinical trials. The collection of tissue within such trials has enabled biomarker studies and evaluation of companion diagnostic tests. Tissue microarrays (TMAs) have become a standard approach in many cooperative oncology groups. A principal goal is to maximize the number of assays with this precious tissue. However, production strategies for these arrays have not been standardized, possibly decreasing the value of the study. In this article, members of the Cancer and Leukemia Group B Pathology Committee relay our experiences as array facility directors and propose guidelines regarding the production of high-quality TMAs for cooperative group studies. We also discuss statistical issues arising from having a proportion of patients available for TMAs and the possibility that patients with TMAs fail to represent the greater study population.

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Jones, Susie, and Manju L. Prasad. "Comparative Evaluation of High-Throughput Small-Core (0.6-mm) and Large-Core (2-mm) Thyroid Tissue Microarray: Is Larger Better?" Archives of Pathology & Laboratory Medicine 136, no. 2 (February 1, 2012): 199–203. http://dx.doi.org/10.5858/arpa.2011-0080-oa.

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Context.—Tissue microarrays (TMAs) are useful in gene/protein expression profiling of large number of tumors. Several studies have validated that a 0.6-mm core of a large tumor would give results similar to results of the whole section. However, cores from colloid-filled thyroid follicles, for example in breast carcinoma, may contain fewer cells compared to solid tumors. Objective.—The aim of this study is to validate thyroid TMAs choosing 2 core diameters, 0.6 and 2 mm, and to study the effect of core size and grid density on concordance with whole sections. Design.—0.6-mm tissue cores were arrayed on a high-density TMA (406 cores). Two low-density TMAs (35 cores each) composed of 2-mm cores were also constructed. Immunohistochemistry was performed using primary antibodies to cytokeratin 19, HBME1, and CITED1 that have been found to be useful in the diagnosis of thyroid carcinoma. The results were compared with whole sections. Results.—The concordance between high-density TMAs and whole sections was 61 of 77 (79%) for cytokeratin 19; 76 of 80 (95%) for HBME 1; and 67 of 75 (89%) for CITED1. The concordance between the low-density TMAs and whole sections was cytokeratin 19, 41 of 51 (80%) for cytokeratin 19; HBME1, 52 of 56 (92.8%) for HBME1 and 58 of 59 (98%) for CITED1. The most frequent discordance was negative core but positive focal heterogeneous protein expression in whole sections. On whole sections, the sensitivity of tests increased but the specificity decreased compared to TMAs; however, the accuracy remained similar (77%–83%). Conclusion.—Focal and heterogeneous protein expression was the most frequent reason for false negative results in TMAs. Tissue microarray remains an accurate method of screening for protein expression in a large number of thyroid tissues irrespective of core diameters or grid densities.

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Ludvigsen, Trine Pagh, Lisbeth Høier Olsen, Henrik Duelund Pedersen, Berit Østergaard Christoffersen, and Lars Jørn Jensen. "Hyperglycemia-induced transcriptional regulation of ROCK1 and TGM2 expression is involved in small artery remodeling in obese diabetic Göttingen Minipigs." Clinical Science 133, no. 24 (December 2019): 2499–516. http://dx.doi.org/10.1042/cs20191066.

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Abstract Obesity and diabetes in humans are associated with hypertrophic remodeling and increased media:lumen ratio of small resistance arteries, which is an independent predictor of cardiovascular events. In order to minimize increases in media:lumen ratio, hypertrophic remodeling should be accompanied by outward remodeling. We aimed to investigate the mechanisms of structural remodeling in small pial arteries (PAs) and terminal mesenteric arteries (TMAs) from obese Göttingen Minipigs with or without diabetes. Göttingen Minipigs received either control diet (lean control (LC)), high fat/high fructose/high cholesterol diet (FFC), or FFC diet with streptozotocin (STZ)-induced diabetes (FFC/STZ) for 13 months. At the end of the study (20 months), we assessed body weight, fasting plasma biochemistry, passive vessel dimensions, mRNA expression (matrix metallopeptidases 2/9 (MMP2, MMP9), tissue inhibitor of metallopeptidase 1 (TIMP1), transglutaminase 2 (TGM2), Rho-kinase 1 (ROCK1), TGFβ-receptor 2 (TGFBR2), and IGF1-receptor (IGFR1) genes), and immunofluorescence in PAs and TMAs. We performed multiple linear correlation analyses using plasma values, structural data, and gene expression data. We detected outward hypertrophic remodeling in TMAs and hypertrophic remodeling in PAs from FFC/STZ animals. ROCK1 and TGM2 genes were up-regulated in PAs and TMAs from the FFC/STZ group. Passive lumen diameter (PLD) of TMAs was correlated with plasma values of glucose (GLU), fructosamine (FRA), total cholesterol (TC), and triglycerides (TGs). ROCK1 and TGM2 expressions in TMAs were correlated with PLD, plasma GLU, fructosamine, and TC. ROCK1 and TGM2 proteins were immunolocalized in the media of PAs and TMAs, and their fluorescence levels were increased in the FFC/STZ group. Hyperglycemia/hyperlipidemia is involved in regulation of ROCK1 and TGM2 expression leading to outward remodeling of small resistance arteries in obese diabetic Göttingen Minipigs.

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Miller, Alexander L., John A. Chiles, Judith K. Chiles, M. Lynn Crismon, A. John Rush, and Steven P. Shon. "The Texas Medication Algorithm Project (TMAP) Schizophrenia Algorithms." Journal of Clinical Psychiatry 60, no. 10 (October 15, 1999): 649–57. http://dx.doi.org/10.4088/jcp.v60n1002.

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Rush, A. John, M. Lynn Crismon, T. Michael Kashner, Marcia G. Toprac, Thomas J. Carmody, Madhukar H. Trivedi, Trisha Suppes, et al. "Texas Medication Algorithm Project, Phase 3 (TMAP-3)." Journal of Clinical Psychiatry 64, no. 4 (April 15, 2003): 357–69. http://dx.doi.org/10.4088/jcp.v64n0402.

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Suppes, Trisha, A. John Rush, Ellen B. Dennehy, M. Lynn Crismon, T. Michael Kashner, Marcia G. Toprac, Thomas J. Carmody, et al. "Texas Medication Algorithm Project, Phase 3 (TMAP-3)." Journal of Clinical Psychiatry 64, no. 4 (April 15, 2003): 370–82. http://dx.doi.org/10.4088/jcp.v64n0403.

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Rigal, L. B., D. K. Maude, J. C. Portal, M. Bennett, K. E. Singer, A. R. Peaker, G. Hill, and M. A. Pate. "Exchange splitting and spin disorder scattering in TmAs." Solid State Communications 106, no. 6 (May 1998): 373–77. http://dx.doi.org/10.1016/s0038-1098(98)00056-8.

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Hong, Kyung Uk, Eunhee Kim, Chang-Dae Bae, and Joobae Park. "TMAP/CKAP2 is essential for proper chromosome segregation." Cell Cycle 8, no. 2 (January 15, 2009): 314–24. http://dx.doi.org/10.4161/cc.8.2.7597.

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Bessant, John. "TMAP: a guide to technology management assessment procedure." Technovation 22, no. 7 (July 2002): 469–70. http://dx.doi.org/10.1016/s0166-4972(01)00101-8.

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Miller, A. L., J. A. Chiles, K. Shores-Wilson, M. M. Biggs, A. Podawiltz, M. L. Crisman, S. Shan, M. Mason, and A. J. Rush. "Feasibility trial of the schizophrenia algorithm in TMAP." Schizophrenia Research 41, no. 1 (January 2000): 230. http://dx.doi.org/10.1016/s0920-9964(00)90877-6.

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41

Ferguson, Jonathan. "Masuh: The 2001 TMAP Topographic and Archaeological Survey." Liber Annuus 63 (January 2013): 423–59. http://dx.doi.org/10.1484/j.la.5.105606.

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42

Matsumoto, Kenji, Noriyuki Tawara, Yurie Shimakawa, and Kazunari Hioki. "Dispatch Reports on Thai Medical Physicist Society (TMPS)." Japanese Journal of Radiological Technology 74, no. 5 (2018): 516–19. http://dx.doi.org/10.6009/jjrt.2018_jsrt_74.5.516.

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Mohammed, Atheer Abdullah, Abdul Hafeez Baig, and Raj Gururajan. "An examination of talent management processes in Australian higher education." International Journal of Productivity and Performance Management 69, no. 6 (January 13, 2020): 1271–99. http://dx.doi.org/10.1108/ijppm-10-2018-0352.

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Purpose The purpose of this paper is to understand the best processes that are currently used in managing talent in Australian higher education (HE) and to examine the policies in terms of talent management processes (TMPs) that are derived from objective one. Pragmatic benefits for academic institutions focused on enhancing talent. Design/methodology/approach This study selects the mixed method as its research design. In the qualitative study, there were three methods: brainstorming, focus group and individual interviews, followed by the quantitative questionnaire study. The sample consisted of 6 participants for brainstorming, 11 in focus group, 6 individual interviews and 286 participants for the quantitative questionnaire, all conducted in nine Australian universities. Findings Three key themes: talent retention, talent development and talent attraction were explored by the qualitative study. The quantitative study tests the level of an importance regarding the three TMPs explored. Practical implications This empirical research is one of the first few studies that extended the previous investigation of TMPs in various industries to the HE sector. This research provides more debates for adding more new ideas in the Australian education strategic plans for HE. Originality/value This study offers a value-add to talent management literature through designing a quantitative measurement of TMPs for the educational sector. Consequently, there is a deficiency of pragmatic evidence in terms of TMPs in the aforementioned sector. Furthermore, this study provides a clear and comprehensive outline of the extant scholarly research of TMPs from the period 2006–2018.

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Matsuyama, Tomomi, Masataka Kuwana, Masanori Matsumoto, Ayami Isonishi, Shigeko Inokuma, and Yoshihiro Fujimura. "Heterogeneous pathogenic processes of thrombotic microangiopathies in patients with connective tissue diseases." Thrombosis and Haemostasis 102, no. 08 (2009): 371–78. http://dx.doi.org/10.1160/th08-12-0825.

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SummaryTo clarify the pathogenic processes of thrombotic microangiopathies (TMAs) in patients with connective tissue disease (CTD), we analysed clinical characteristics and plasma ADAMTS13 levels in 127 patients with CTD-TMAs, including patients with systemic lupus erythematosus (SLE), systemic sclerosis, polymyositis/dermatomyositis, and rheumatoid arthritis (RA), and 64 patients with acquired idiopathic thrombotic thrombocytopenic purpura (ai-TTP). Plasma levels of ADAMTS13 activity, antigen, and inhibitors were determined by enzyme immunoassays. IgG type anti-ADAMTS13 antibodies were also detected by immunoblots using purified ADAMTS13. ADAMTS13 activity was significantly decreased in CTD-TMAs, regardless of the underlying disease, but the frequency of severe deficiency (defined as <0.5% of normal) was lower in CTD-TMA patients than in ai-TTP patients (16.5% vs.70.3%,p<0.01). Severe deficiency of ADAMTS13 activity was predominantly detected in patients with RA and SLE-TMAs, and was closely associated with the presence of anti-ADAMTS13 IgG antibodies. CTD-TMA patients with severe deficiency of ADAMTS13 activity appeared to have lower platelet counts and better therapeutic outcomes. At least two phenotypic TMAs occur in patients with CTDs: a minor population with deficient ADAMTS13 activity caused by neutralising autoantibodies, and a major population with normal or moderately reduced activity. Classifying CTD-TMAs by ADAMTS13 activity may be useful in predicting the clinical course and therapeutic outcomes, as patients with moderately reduced activity are likely to have more prominent renal impairment and poor prognoses.

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Jiang, Mingfeng, Feng Liu, Yaming Wang, Guofa Shou, Wenqing Huang, and Huaxiong Zhang. "A Hybrid Model of Maximum Margin Clustering Method and Support Vector Regression for Noninvasive Electrocardiographic Imaging." Computational and Mathematical Methods in Medicine 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/436281.

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Noninvasive electrocardiographic imaging, such as the reconstruction of myocardial transmembrane potentials (TMPs) distribution, can provide more detailed and complicated electrophysiological information than the body surface potentials (BSPs). However, the noninvasive reconstruction of the TMPs from BSPs is a typical inverse problem. In this study, this inverse ECG problem is treated as a regression problem with multi-inputs (BSPs) and multioutputs (TMPs), which will be solved by the Maximum Margin Clustering- (MMC-) Support Vector Regression (SVR) method. First, the MMC approach is adopted to cluster the training samples (a series of time instant BSPs), and the individual SVR model for each cluster is then constructed. For each testing sample, we find its matched cluster and then use the corresponding SVR model to reconstruct the TMPs. Using testing samples, it is found that the reconstructed TMPs results with the MMC-SVR method are more accurate than those of the single SVR method. In addition to the improved accuracy in solving the inverse ECG problem, the MMC-SVR method divides the training samples into clusters of small sample sizes, which can enhance the computation efficiency of training the SVR model.

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Huang, Song, Edison Huixiang, Yang Yang, Yufei Zhang, Minghui Ye, and Cheng Chao Li. "Transition metal phosphides: new generation cathode host/separator modifier for Li–S batteries." Journal of Materials Chemistry A 9, no. 12 (2021): 7458–80. http://dx.doi.org/10.1039/d0ta11919a.

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This article summarizes the latest progress on TMPs for Li–S batteries in recent years, with a particular focus on the adsorption and catalysis of TMPs to PS, also including synthesis strategies, challenges and opportunities in the future.

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Huang, Weihong, Ping Xu, Wenming Yang, and Wanzhen Xu. "Thermosensitive molecularly imprinted polymers based on magnetic nanoparticles for the recognition of sulfamethazine." RSC Advances 6, no. 78 (2016): 74734–41. http://dx.doi.org/10.1039/c6ra16162f.

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Rock, Gail, William Clark, Ronan Foley, Susan Huang, Vincent Laroche, John Klassen, Christopher Patriquin, and Katrina Pavenski. "TTP: One of the TMA’s—How to sort it out." Transfusion and Apheresis Science 56, no. 1 (February 2017): 57–58. http://dx.doi.org/10.1016/j.transci.2016.12.020.

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Chang, Kai, Guang Ren Sun, and Da Di Yao. "Optimization of Extraction of Bioactive Material-Polysaccharides from the Roots of Taraxacum mongolicum by Box-Behnken Experimental Design." Advanced Materials Research 749 (August 2013): 354–58. http://dx.doi.org/10.4028/www.scientific.net/amr.749.354.

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Dandelion (Taraxacum spp) is an medical active materials used in many traditional and modern herbal medical systems, its polysaccharides have many bioactivities. Taraxacum mongolicum is one of the most widely consumed as Chinese herbal medicine and root tea in Changbai Mountains area, Northeast China. In this study, a procedure for the extraction of polysaccharides from the root of T mongolicum(TMRPS) was established. Based on single-variable tests experiment to determine the ranges of the extraction parameters (extraction temperature (X1), extraction time (X2), and ratio of solvent to raw material (X3)), response surface methodology (RSM) was used to optimize for these extraction parameters (X1, X2, X3) enhancing the forward extraction efficiency of TMRPS by a three-level three-variable Box-Behnken experimental design. The results showed that the ranges of the extraction parameters were determined as 60°C-80°C(X1),1h-3h (X2),20-40(v/m)(X3) by single-variable tests and the maximal yield (9.01%) of TMRPS was reached at extraction temperature 70.2°C, extraction time 1.79 h and ratio of solvent to raw material 28.0 (v):1 (m). Convenient for experiment, appropriate readjustment of these extraction parameters was made. Under these readjusted conditions, the mean extraction yield of TMRPS was 8.85%, which was near to theoretical calculation and indicates that these results were agree closely with model predictions.

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Duda, Kusuma, Gaddipati R, Ramsetti S, and Suvvada B. "Transmasseteric antero-parotid approach through modified preauricular lazy ‘S’ incision for management of mandible condylar fractures: a prospective study." Journal of Dental and Maxillofacial Surgery 1, no. 1 (December 18, 2018): 85–89. http://dx.doi.org/10.18314/jdms.v1i1.1436.

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To report the surgical details and results of our technique of Transmasseteric antero-parotid approach (TMAP) through modified preauricular lazy ‘S’ incision for management of mandibular condylar fractures. This was an observational analysis of 65 patients where 25 patients were treated with conventional preauricular approach, 25 patients with closed reduction and 15 patients with a mean age of 29.4 years with condylar fractures were treated by TMAP technique between September 2016 to June 2018. Aim of the study was to evaluate the proficiency of TMAP approach for open reduction and internal fixation (ORIF) of condylar fracture. The only complication which was noticed was sialocele formation and managed by drainage. TMAP is versatile since it avoids facial nerve damage as it involves identification and preservation of facial nerve and has less chances of post-operative complications related to facial nerve injury. The accessibility achieved by this approach is fair enough to facilitate anatomic reduction and fixation of condyle.

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