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Journal articles on the topic 'TNSRC'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Yilkal, Bezie Ayele, Tefera Wondyifraw, and Bantte Kassahun. "Enhanced Protocol Development for in vitro Multiplication and Rooting of Vanilla (Vanilla planifolia Andr.) Clone (Van.2/05)." Biotechnology Journal International 18, no. 3 (2017): 1–11. https://doi.org/10.9734/BJI/2017/33726.

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Vanilla (<em>Vanilla planifolia Andr</em>.) is a multipurpose spice in the world. The crop had been introduced to Ethiopia from Mauritius and it is still under maintenance at the Tepi National Spices Research Center (TNSRC). It is commonly propagated through stem cuttings which could arrests subsequent plant growth and development and serves as an ideal means for the spread of varied diseases. To solve the mentioned problems, no efficient <em>in vitro</em> protocol had so far been developed to propagate this vanilla clone in Ethiopia. Therefore, this study was initiated to address this gap by

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Botelho, Michelle R., and Justine E. Vanden Heuvel. "Preliminary Assessment of the Impact of Current Flooding Practices on Nonstructural Carbohydrate Concentrations of Cranberry." HortTechnology 16, no. 2 (2006): 277–85. http://dx.doi.org/10.21273/horttech.16.2.0277.

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American cranberry (Vaccinium macrocarpon) production sites are often flooded for pest control and crop harvest. However, little is known about how this practice affects vines. A survey was conducted in Massachusetts over a 3-year period to determine the effect of spring, fall, and winter floods on total nonstructural carbohydrate concentration (TNSC) of cranberry uprights of four cultivars. With a few exceptions, TNSC generally was unaffected or increased during the course of the 1-month “late water” flood held from mid-April to mid-May. The 48-hour “flash” flood, held in mid- to late May, ge

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Traina-Dorge, Vicki L., Rebecca Lorino, Bobby J. Gormus, et al. "Molecular Epidemiology of Simian T-Cell Lymphotropic Virus Type 1 in Wild and Captive Sooty Mangabeys." Journal of Virology 79, no. 4 (2005): 2541–48. http://dx.doi.org/10.1128/jvi.79.4.2541-2548.2005.

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ABSTRACT A study was conducted to evaluate the prevalence and diversity of simian T-cell lymphotropic virus (STLV) isolates within the long-established Tulane National Primate Research Center (TNPRC) colony of sooty mangabeys (SMs; Cercocebus atys). Serological analysis determined that 22 of 39 animals (56%) were positive for STLV type 1 (STLV-1). A second group of thirteen SM bush meat samples from Sierra Leone in Africa was also included and tested only by PCR. Twenty-two of 39 captive animals (56%) and 3 of 13 bush meat samples (23%) were positive for STLV-1, as shown by testing with PCR. N

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Traina-Dorge, V. L., R. Lorino, B. J. Gormus, et al. "Molecular epidemiology of simian T-cell lymphotropic virus type 1 in wild and captive sooty mangabeys." Journal of virology 79, no. 4 (2005): 2541–48. https://doi.org/10.5281/zenodo.14822542.

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(Uploaded by Plazi for the Bat Literature Project) A study was conducted to evaluate the prevalence and diversity of simian T-cell lymphotropic virus (STLV) isolates within the long-established Tulane National Primate Research Center (TNPRC) colony of sooty mangabeys (SMs; Cercocebus atys). Serological analysis determined that 22 of 39 animals (56%) were positive for STLV type 1 (STLV-1). A second group of thirteen SM bush meat samples from Sierra Leone in Africa was also included and tested only by PCR. Twenty-two of 39 captive animals (56%) and 3 of 13 bush meat samples (23%) were positive f

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Satterlee, Andrew B., Denise E. Dunn, Donald C. Lo, Simon Khagi, and Shawn Hingtgen. "Tumoricidal stem cell therapy enables killing in novel hybrid models of heterogeneous glioblastoma." Neuro-Oncology 21, no. 12 (2019): 1552–64. http://dx.doi.org/10.1093/neuonc/noz138.

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Abstract Background Tumor-homing tumoricidal neural stem cell (tNSC) therapy is a promising new strategy that recently entered human patient testing for glioblastoma (GBM). Developing strategies for tNSC therapy to overcome intratumoral heterogeneity, variable cancer cell invasiveness, and differential drug response of GBM will be essential for efficacious treatment response in the clinical setting. The aim of this study was to create novel hybrid tumor models and investigate the impact of GBM heterogeneity on tNSC therapies. Methods We used organotypic brain slice explants and distinct human

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Adhithya, Mr P., and Mr S. Kamalakannan. "POST-RETIREMENT LIFESTYLE OF TNSTC EMPLOYEES." International Scientific Journal of Engineering and Management 04, no. 04 (2025): 1–7. https://doi.org/10.55041/isjem02724.

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The retirement lifestyle of Tamil Nadu State Transport Corporation (TNSTC) staff is a key change from a busy, routine-driven professional life to a less hectic and personally controlled way of life. This research examines different aspects of their life after retirement, such as financial security, health, social interaction, psychological adaptation, and family support. Most retirees experience difficulties associated with restricted pension benefits, health problems resulting from years of work-related stress, and the necessity for meaningful involvement. Simultaneously, others discover new

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Vanden Heuvel, Justine. "THE EFFECT OF FLOOD WATER TEMPERATURE ON CRANBERRY UPRIGHTS AND ROOTS DURING SPRING AND FALL FLOODS." HortScience 41, no. 3 (2006): 495C—495. http://dx.doi.org/10.21273/hortsci.41.3.495c.

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Cranberry bogs are flooded for several purposes during the growing season, including pest control and harvest. A spring `late water' and a fall `harvest' flood were simulated on potted cranberry uprights (`Stevens'). The `late water' flood is a 1-month flood held on some Massachusetts bogs from mid-April to mid-May. The flood was simulated at 11 and 21 °C. Over the course of the 1-month flood, total non-structural carbohydrate concentration (TNSC) of the upright tissue decreased by 13% and 46% in the 11 and 21 °C treatments, respectively. Root TNSC was not affected by flooding in the 11 °C tre

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Vanden Heuvel, Justine E. "Flood Water Temperature and Duration Affect Nonstructural Carbohydrate Concentration of Cranberry Uprights and Roots." HortScience 40, no. 4 (2005): 1127D—1127. http://dx.doi.org/10.21273/hortsci.40.4.1127d.

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Flooding is often used as a pest management tool in cranberry production. The “Late Water” flood is a 1-month flood held on some Massachusetts bogs from mid-April to mid-May, and has anecdotally been related to poor vine performance. The flood was simulated at 11 °C and 21 °C on potted cranberry uprights (cv. Stevens). Over the course of the 1-month flood, total nonstructural carbohydrate concentration (TNSC) of the upright tissue decreased by 23% and 50% in the 11 °C and 21 °C treatments, respectively. Decreases in upright TNSC in the 11 °C treatment were mostly due to a substantial decrease

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Alberti, Paola, Davide P. Bernasconi, David R. Cornblath, et al. "Prospective Evaluation of Health Care Provider and Patient Assessments in Chemotherapy-Induced Peripheral Neurotoxicity." Neurology 97, no. 7 (2021): e660-e672. http://dx.doi.org/10.1212/wnl.0000000000012300.

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Background and ObjectiveThere is no agreement on the gold standard for detection and grading of chemotherapy-induced peripheral neurotoxicity (CIPN) in clinical trials. The objective is to perform an observational prospective study to assess and compare patient-based and physician-based methods for detection and grading of CIPN.MethodsConsecutive patients, aged 18 years or older, candidates for neurotoxic chemotherapy, were enrolled in the United States, European Union, or Australia. A trained investigator performed physician-based scales (Total Neuropathy Score–clinical [TNSc], used to calcul

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Ferris, Daniel P., and Kara Mcarthur. "TNSRE Is Flipping to Full Open Access." IEEE Transactions on Neural Systems and Rehabilitation Engineering 28, no. 7 (2020): 1510. http://dx.doi.org/10.1109/tnsre.2020.3004668.

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Park, Jung-Un, Amy Wei-Lun Tsai, Eshan Mehrotra, et al. "Structural basis for target site selection in RNA-guided DNA transposition systems." Science 373, no. 6556 (2021): 768–74. http://dx.doi.org/10.1126/science.abi8976.

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CRISPR-associated transposition systems allow guide RNA–directed integration of a single DNA cargo in one orientation at a fixed distance from a programmable target sequence. We used cryo–electron microscopy (cryo-EM) to define the mechanism that underlies this process by characterizing the transposition regulator, TnsC, from a type V-K CRISPR-transposase system. In this scenario, polymerization of adenosine triphosphate–bound TnsC helical filaments could explain how polarity information is passed to the transposase. TniQ caps the TnsC filament, representing a universal mechanism for target in

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Azoulay, David, Anca Leibovici, Rivka Sharoni, and Hadassah Goldberg. "Association of Met-BDNF allele with pre-existing peripheral neuropathy in breast cancer patients." Journal of Clinical Oncology 35, no. 15_suppl (2017): e21702-e21702. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e21702.

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e21702 Background: We previously published preliminary results suggesting an association between the met-BDNF allele and vulnerability to paclitaxel-induced peripheral neuropathy (PIPN) in breast cancer patients. Here we present updated data obtained from our extended study. Methods: 35 patients; 34 women (33 with breast cancer and 1 with ovarian cancer) and one man (breast cancer) completed their follow-up. Peripheral neuropathy (PN) was assessed at diagnosis and along the treatment protocol, using the reduced version of Total Neuropathy Score (TNSr). Patients with TNSr≥2 at diagnosis were de

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Schaffer, B., J. A. Bar den, and J. M. Williams. "Whole Plant Photosynthesis and Dry-matter Partitioning in Fruiting and Deblossomed Day-neutral Strawberry Plants." Journal of the American Society for Horticultural Science 111, no. 3 (1986): 430–33. http://dx.doi.org/10.21273/jashs.111.3.430.

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Abstract On a whole-plant basis, deblossomed ‘Tribute’ strawberry plants had higher rates of net photosynthesis (Pn) and greater leaf area than fruiting plants during the last 3 weeks of a 6-week fruiting cycle. Leaves of both fruiting and deblossomed plants had a greater dry weight and total nonstructural carbohydrate (TNSC) content than the roots, crown, or fruit. At the end of the fruiting cycle, dry weight and TNSC content of leaves were higher for deblossomed plants than fruiting plants. There was no difference in crown or root dry weights between treatments. Pn was highly correlated with

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Heuvel*, Justine E. Vanden, Jessica L. Robidoux, and Catherine C. Neto. "Leaf Carbohydrate Concentration Affects Development of Phenolic Compounds in Grape Berries." HortScience 39, no. 4 (2004): 761B—761. http://dx.doi.org/10.21273/hortsci.39.4.761b.

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Carbon supply reduction was used to investigate the relationship between total non-structural carbohydrate (TNSC) concentration in the vegetative tissue and the production of phenolic compounds in the fruit of grapevines. Potted, greenhouse-grown DeChaunac vines were partially defoliated on one of three dates (berry set, veraison, or 7 days pre-harvest) during the growing season. Light environment of the fruit clusters was not affected by defoliation. Seven days following defoliation, half of the vines were destructively harvested for carbohydrate analysis, while the remaining vines were kept

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Stellwagen, Anne E., and Nancy L. Craig. "Gain-of-Function Mutations in TnsC, an ATP-Dependent Transposition Protein That Activates the Bacterial Transposon Tn7." Genetics 145, no. 3 (1997): 573–85. http://dx.doi.org/10.1093/genetics/145.3.573.

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The bacterial transposon Tn7 encodes five genes whose protein products are used in different combinations to direct transposition to different types of target sites. TnsABC+D directs transposition to a specific site in the Escherichia coli chromosome called attTn7, whereas TnsABC+E directs transposition to non-attTn7 sites. These transposition reactions can also recognize and avoid “immune” targets that already contain a copy of Tn7. TnsD and TnsE are required to activate TnsABC as well as to select a target site; no transposition occurs with wild-type TnsABC alone. Here, we describe the isola

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Hurtado Martinez, Jorge Arturo Arturo, Patricia Alejandra Flores Pérez, Felipe Flores Quiroz, et al. "Unraveling the Dynamics of Protein Secretion in Multiple Myeloma: A Comparative Study of Non-Secretory Patterns and Disease Evolution." Blood 142, Supplement 1 (2023): 6704. http://dx.doi.org/10.1182/blood-2023-190557.

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Background Non-secretory multiple myeloma (NSMM), 1-2% of all multiple myeloma (MM) cases, was traditionally defined by the absence of detectable M-Spike in serum or urine. Advancements in diagnostic methodologies have revealed that a proportion of NSMMs are, in fact, more accurately categorized as oligo-secretory, highlighting the dynamic nature of MM and its classification. Disease evolution, especially towards less secretory types, significantly impacts monitoring, progression, and prognosis. This study examines MM secretion patterns (SP) and evolution, particularly NSMM and oligo-secretory

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Zhang, Xiaopei, Denise Dunn, Alain Valdivia, et al. "MODL-14. MODELING THE INTRATUMORAL HETEROGENEITY OF AGGRESSIVE GLIOBLASTOMA ON ORGANOTYPIC BRAIN SLICES TO OPTIMIZE TUMOR-HOMING TUMORICIDAL INSC TREATMENT." Neuro-Oncology 24, Supplement_7 (2022): vii293—vii294. http://dx.doi.org/10.1093/neuonc/noac209.1142.

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Abstract BACKGROUND Tumor-homing tumoricidal neural stem cell (tNSC) therapy is a promising new strategy that recently entered human patient testing for glioblastoma (GBM). Developing strategies for tNSC therapy to overcome intratumoral heterogeneity, variable cancer cell invasiveness, and differential drug response of GBM will be essential for efficacious treatment response in the clinical setting. We sought to create novel hybrid tumor models and investigate the impact of GBM heterogeneity on tNSC tumor response and treatment durability. METHODS We utilized organotypic brain slice explants a

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Cavaletti, Guido, Chiara Pizzamiglio, Albert Man, Thomas M. Engber, Cristoforo Comi, and Darren Wilbraham. "Studies to Assess the Utility of Serum Neurofilament Light Chain as a Biomarker in Chemotherapy-Induced Peripheral Neuropathy." Cancers 15, no. 17 (2023): 4216. http://dx.doi.org/10.3390/cancers15174216.

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Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common and disabling dose-limiting toxicities of chemotherapy. We report here the results of two separate non-interventional studies (49 patients), which evaluated blood neurofilament light chain (NfL) as a biomarker of CIPN in breast cancer patients treated with paclitaxel. All patients underwent a standard treatment protocol that was established independently of the present studies. NfL was measured in serum using an ultrasensitive single-molecule array and compared with the self-administered European Organization for Resea

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Ferris, Daniel P., and He Huang. "Editorial IEEE TNSRE Has a New Editor-in-Chief!!" IEEE Transactions on Neural Systems and Rehabilitation Engineering 31 (2023): 4978–79. http://dx.doi.org/10.1109/tnsre.2023.3345053.

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Vanden Heuvel, Justine E., and Joan R. Davenport. "(124) The Impact of Nitrogen Application on Nonstructural Carbohydrate Production in Cranberry Leaves." HortScience 41, no. 4 (2006): 1061C—1061. http://dx.doi.org/10.21273/hortsci.41.4.1061c.

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Five fertilizer treatments were applied to a `Stevens' cranberry bed in a 3-way split application (roughneck, 75% bloom, and 3 weeks after bloom) in Spring 2004 at State Bog in E. Wareham, Mass. Nitrogen rates were 0, 22, 45, 67, and 90 kg/ha; P was applied at 22 kg/ha, and K at 44 kg/ha. At mid-fruit development and again at preharvest, 20 vegetative and 20 fruiting uprights were collected from each plot in mid-morning. The N concentration per upright increased linearly with increased N application. Increased upright N concentration had no effect on soluble carbohydrate (sucrose + glucose + f

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Baez Camargo, Claudia, and Gayle Burgess. "Working Paper 39: Behavioural drivers of corruption facilitating illegal wildlife trade." Basel Institute on Governance Working Papers, no. 39 (June 2, 2022): 1–61. http://dx.doi.org/10.12685/bigwp.2022.39.1-61.

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This Problem Analysis is a review of the efficacy and opportunities for using social norm and behaviour change (SNBC) approaches to combat illegal wildlife trade (IWT) and other natural resource-related corruption. Behavioural science is a rich and expansive field that has received prominent coverage in recent years for the promise it offers as a foundational yet underutilised approach to achieving biodiversity conservation. Extensive literature shows how SNBC initiatives can help combat diverse corruption problems, although for those related to natural resource management the evidence f

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Acuña Lugo, Martin, Silvana Espinosa, and Viviana Navarro. "Los hoteles de campo y el transporte de lana en la conformación del espacio rural del NO del Territorio Nacional de Santa Cruz (1880-1950)." Informes Científicos Técnicos - UNPA 12, no. 3 (2020): 1–26. http://dx.doi.org/10.22305/ict-unpa.v12.n3.738.

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El presente trabajo brinda un panorama acerca de los hoteles de campo y el transporte de la lana en la conformación del espacio rural del NO del Territorio Nacional de Santa Cruz (TNSC) entre los años 1880-1950. El análisis de la historia de los Hoteles “Riera”, “Las Horquetas”, “Olnie” y ”Bajo Caracoles” -antiguos boliches de la región- resulta revelador de un mundo rural dinámico, con una intensa vida social, en una región que hasta ahora había sido caracterizada por la historiografía como un espacio despoblado y marginal a los grandes centros de actividad económica del TNSC.

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Heuvel*, Justine E. Vanden. "Source-Sink Relationships in Cranberry: Effects on Carbohydrate Production and Partitioning." HortScience 39, no. 4 (2004): 761A—761. http://dx.doi.org/10.21273/hortsci.39.4.761a.

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Fruiting and vegetative greenhouse-grown cranberry uprights (Vaccinium macrocarpon Ait.) were subjected to four defoliation levels (0%, 25%, 50%, 75%) on one of three dates during the growing season. Seven days following defoliation, vines were destructively harvested and carbohydrate concentration was quantified using HPLC. Prior to new growth, defoliation did not affect the concentration of total non-structural carbohydrates (TNSC) in the uprights, or the partitioning of water-soluble (i.e., sucrose, glucose, fructose) to ethanol-insoluble (i.e., starch) carbohydrates, even though uprights w

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SHENBER *, M. A., M. N. ELAYAN, and M. E. FLEFEL. "Environmental Gamma radiation measurement using TLDs around TNRC, tripoli." International Journal of Environmental Studies 61, no. 5 (2004): 509–13. http://dx.doi.org/10.1080/0020723022000026301.

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Cavaletti, Guido. "The chemotherapy-induced peripheral neuropathy (CIPN) outcome measure standardization (CI-PeriNomS) study: From consensus to validity and reliability in CIPN assessment." Journal of Clinical Oncology 30, no. 15_suppl (2012): 9089. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.9089.

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9089 Background: Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a debilitating and dose limiting complication of cancer treatment. However, the impact of CIPN has never been studied in a clinimetric manner, in its impact on quality of life. This study was performed to select appropriate outcome measures and to establish, for the first time with a clinimetric approach, their validity and reproducibility. Methods: After literature review and a consensus meeting, face/content validity were obtained for the following scales: the National Cancer Institute Common-Toxicity-Criteria (NCI-CTC), t

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M., Neela. "A Study on Passengers Satisfaction towards Transport Services of TNSTC Buses." Shanlax International Journal of Commerce 6, S2 (2018): 34–38. https://doi.org/10.5281/zenodo.3243781.

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The aim of this study is to  gure out what factors are most important in explaining  different level of satisfaction concerning passengers with regard to Transport Corporation, Problem faced by such passengers and to provide suggestions to overcome the problems .The state road transport undertakings have a place of prominence in the road transport sector. They perform very vital road in the daily life of millions of our country. The STUs carried (satisfaction, there  nancial position of STU in India had been for from satisfactory).

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Zambello, Renato, Tamara Berno, Laura Candiotto, et al. "Lenalidomide Therapy Is Associated with Improvement of Peripheral Neuropathy in Patient with Relapsed/Refractory Multiple Myeloma: Preliminary Results From a Single-Centre Prospective Non Interventional Study." Blood 114, no. 22 (2009): 4949. http://dx.doi.org/10.1182/blood.v114.22.4949.4949.

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Abstract Abstract 4949 In recent years, proteasome inhibitors and immunomodulatory drugs (IMIDs) have provided invaluable advantage in the therapy of multiple myeloma (MM) in terms of disease free survival and often overall survival. However the benefits have sometimes been blunted by the occurrence of adverse effects which strongly impact quality of life. Among them, peripheral neuropathy (PN) represents one of the most disabling and often dose-limiting side effect. Lenalidomide, a second generation IMID and a structural analogue of thalidomide, has been claimed to have low toxicity on periph

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Yang, Kuo-Liang, Mei-Fang Chen, Chia-Hsin Liao, Chen-Yoong Pang, and Py-Yu Lin. "A simple and efficient method for generating Nurr1-positive neuronal stem cells from human wisdom teeth (tNSC) and the potential of tNSC for stroke therapy." Cytotherapy 11, no. 5 (2009): 606–17. http://dx.doi.org/10.1080/14653240902806994.

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Souther, Sara, Vincent Randall, and Nanebah Lyndon. "The Use of Citizen Science to Achieve Multivariate Management Goals on Public Lands." Diversity 13, no. 7 (2021): 293. http://dx.doi.org/10.3390/d13070293.

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Federal land management agencies in the US are tasked with maintaining the ecological integrity of over 2 million km2 of land for myriad public uses. Citizen science, operating at the nexus of science, education, and outreach, offers unique benefits to address socio-ecological questions and problems, and thus may offer novel opportunities to support the complex mission of public land managers. Here, we use a case study of an iNaturalist program, the Tribal Nations Botanical Research Collaborative (TNBRC), to examine the use of citizen science programs in public land management. The TNBRC colle

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M. Ganesan, K, K. Veerakumar, N. R Vembu, Dr. M. K Durgamani, and Dr. Renuka. "A Study on Job Satisfaction among Tamil Nadu State Transport Corporation (TNSTC) Employees at Tiruvarur Branch." GIS Business 14, no. 6 (2019): 230–42. http://dx.doi.org/10.26643/gis.v14i6.11703.

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Job satisfaction is an important factor for employees working in formal and informal sector. The job is small or big, permanent or temporary, risky or non-risky, job satisfaction is important. It is the mental feeling which drives the employees to excel. Job satisfaction is a combination of psychological, physiological and environmental circumstances. A satisfied employee is a contented and happy human being. The labour turnover depends upon job satisfaction. Even highly paid employees quit the job when they are not satisfied with the job. Road transportation in Tamilnadu is growing day by day

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Martinho, Teresa Duarte, and José Nuno Matos. "COMO GOVERNAR O ÚNICO TEATRO DE ÓPERA EM PORTUGAL? A incerteza permanente do estatuto do Teatro Nacional de São Carlos." Revista Lusófona de Estudos Culturais 2, no. 2 (2014): 165–87. http://dx.doi.org/10.21814/rlec.73.

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Fundado em 1793, o Teatro Nacional de São Carlos (TNSC) é uma referência no campo da difusão e da produção de ópera em Portugal. Considerando o período entre 1974 e 2013, o presente artigo tem como principal objetivo compreender a evolução dos vários estatutos do TNSC e das lógicas que os enformam. A partir da análise de documentação jurídica, bem como de relatórios de gestão e de monografias dedicadas à história do referido teatro, é possível identificar ao longo deste período a oscilação entre dois paradigmas: o da gestão pública, que coloca a instituição sob a alçada direta do Estado, ident

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Dang, Xuan Thi, Thanh Xuan Nguyen, Thu Thi Hoai Nguyen, and Hung Tran Ha. "Nitrous Oxide-Induced Neuropathy among Recreational Users in Vietnam." International Journal of Environmental Research and Public Health 18, no. 12 (2021): 6230. http://dx.doi.org/10.3390/ijerph18126230.

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Nitrous oxide (N2O) commonly referred to as laughing gas, has significant medical uses. This study aims to describe the neurological disorders associated with N2O. We conducted across-sectional study that enrolled patients with nitrous oxide toxicity admitted to Vietnam Poison Control Center, Bach Mai Hospital, Hanoi, Vietnam from June 2018 to July 2019. The questionnaire included demographic characteristics, characteristics of using N2O, signs and clinical symptoms, neuroimaging findings, injury on electromyography (EMG) and the Total Neuropathy Score clinical version (TNSc) criteria. A total

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Thang, Morrent, Clara Mellows, Breanna Mann, et al. "EXTH-13. ENHANCING INDUCED NEURAL STEM CELL-BASED TRAIL THERAPY FOR GLIOBLASTOMA THROUGH COMBINATION WITH THE NOVEL SENSITIZING AGENT TR-107." Neuro-Oncology 25, Supplement_5 (2023): v226. http://dx.doi.org/10.1093/neuonc/noad179.0867.

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Abstract Tumor-homing neural stem cell therapy (tNSC) is emerging as a promising treatment for aggressive cancers of the brain. Despite their success, developing tNSC therapies that maintain durable tumor suppression remains a challenge. Here, we report a new synergistic combination regimen where the novel agent TR107 augments induced NSC-TRAIL therapy (hiNeuroS-TRAIL) in models of the incurable brain cancer glioblastoma (GBM). We found that the combination of hiNeuroS-TRAIL and TR-107 synergistically upregulated caspase markers and restored the sensitivity to the intrinsic apoptotic pathway b

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Yeung, Nicole, Hui-Ming Lin, Hannah Timmins, et al. "Plasma lipidomic profiling of chemotherapy-induced peripheral neuropathy." Journal of Clinical Oncology 41, no. 16_suppl (2023): 3031. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.3031.

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3031 Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of cytotoxic cancer treatment. This may result in dose reduction (DR) or chemotherapy discontinuation (CD) and ultimately decrease the efficacy of therapy. There is a lack of studies examining the role of lipids in relation to CIPN, despite the association of obesity with worse CIPN, and hyperlipidaemia with diabetic neuropathy. The aim of this study is to determine if circulating lipids are associated with CIPN severity. Methods: Pre-chemotherapy plasma samples from 137 patients with CIPN from do

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Smith, Ellen M. Lavoie, Robert Knoerl, James J. Yang, Grace Kanzawa-Lee, Deborah Lee, and Celia M. Bridges. "In Search of a Gold Standard Patient-Reported Outcome Measure for Use in Chemotherapy- Induced Peripheral Neuropathy Clinical Trials." Cancer Control 25, no. 1 (2018): 107327481875660. http://dx.doi.org/10.1177/1073274818756608.

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Purpose: To test a reduced version—CIPN15—of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Chemotherapy-Induced Peripheral Neuropathy scale (QLQ-CIPN20) to establish a possible gold-standard patient-reported outcome measure for chemotherapy-induced peripheral neuropathy (CIPN). Methods: Using a prospective, longitudinal, case–control design, patients (n = 121) receiving neurotoxic chemotherapy completed the CIPN15 at baseline and 12 weeks and underwent objective neurological assessment using the 5-item Total Neuropathy Score-Clinical (TNSc

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Hossain, Amer A., and Luciano A. Marraffini. "CRISPR-assisted transposition: TnsC finds (and threads) the needle in the haystack." Molecular Cell 82, no. 21 (2022): 3968–69. http://dx.doi.org/10.1016/j.molcel.2022.10.014.

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Dr., P. Sabarinathan, and Shanmuga Saranya P. "AN OCCUPATIONAL STRESS OF TNSTC EMPLOYEES (A STUDY WITH SPECIAL REFERENCE TO POLLACHI BRANCH)." International Journal of Applied and Advanced Scientific Research 2, no. 2 (2017): 299–303. https://doi.org/10.5281/zenodo.1117196.

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In the fast changing world of today, no individual is free from stress and no profession is stress free. Everyone experiences stress, whether it is within the family, business, organization, study, work, or any other social or economical activity. Thus in modern time, stress in general and job stress in particular has become a part of the life and has received considerable attention in recent years. Stress has become the core concern in the life of everyone, but everybody wants stress-free life. Not only just high pressure executives are its key victims but it also includes laborers’, sl

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Lin, Huang-Chen, and Shyh-Hau Wang. "Window-Modulated Compounding Nakagami Parameter Ratio Approach for Assessing Muscle Perfusion with Contrast-Enhanced Ultrasound Imaging." Sensors 20, no. 12 (2020): 3584. http://dx.doi.org/10.3390/s20123584.

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The assessment of microvascular perfusion is essential for the diagnosis of a specific muscle disease. In comparison with the current available medical modalities, the contrast-enhanced ultrasound imaging is the simplest and fastest means for probing the tissue perfusion. Specifically, the perfusion parameters estimated from the ultrasound time-intensity curve (TIC) and statistics-based time–Nakagami parameter curve (TNC) approaches were found able to quantify the perfusion. However, due to insufficient tolerance on tissue clutters and subresolvable effects, these approaches remain short of re

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Farkas, Tibor, Robert W. Cross, Edwin Hargitt, Nicholas W. Lerche, Ardythe L. Morrow, and Karol Sestak. "Genetic Diversity and Histo-Blood Group Antigen Interactions of Rhesus Enteric Caliciviruses." Journal of Virology 84, no. 17 (2010): 8617–25. http://dx.doi.org/10.1128/jvi.00630-10.

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ABSTRACT Recently, we reported the discovery and characterization of Tulane virus (TV), a novel rhesus calicivirus (CV) (T. Farkas, K. Sestak, C. Wei, and X. Jiang, J. Virol. 82:5408-5416, 2008). TV grows well in tissue culture, and it represents a new genus within Caliciviridae, with the proposed name of Recovirus. We also reported a high prevalence of CV antibodies in macaques of the Tulane National Primate Research Center (TNPRC) colony, including anti-norovirus (NoV), anti-sapovirus (SaV), and anti-TV (T. Farkas, J. Dufour, X. Jiang, and K. Sestak, J. Gen. Virol. 91:734-738, 2010). To broa

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Maschio, Marta, Andrea Maialetti, Francesco Marchesi, et al. "Prevention of Bortezomib-Induced Peripheral Neuropathy in Newly Multiple Myeloma Patients Using Nervonic Acid, Curcuma Rizoma, and L-Arginine Compound: A Pilot Study." Integrative Cancer Therapies 21 (January 2022): 153473542211141. http://dx.doi.org/10.1177/15347354221114142.

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Introduction: This is a phase II pilot study to evaluate the efficacy of a nutraceutical compound composed of nervonic acid, curcuma rizoma, and l-Arginine to prevent the onset of bortezomib-induced peripheral neuropathy (BIPN) in 16 newly diagnosed multiple myeloma (MM) patients treated with bortezomib (BTZ) over 6 months. Materials and methods: Assessments included neurological examination and electroneurography, Common Terminology Criteria for Adverse Events (NCI-CTCAE), reduced version of Total Neuropathic Score (TNSr), pain evaluation, functional autonomy scales, self-perceived symptoms a

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Zhu, Lin, Shu Hua Li, Zong Suo Liang, Zhan Feng Zhang, and Xing Xu. "Relationship between yield, carbon isotope discrimination and stem carbohydrate concentration in spring wheat grown in Ningxia Irrigation Region (North-west China)." Crop and Pasture Science 61, no. 9 (2010): 731. http://dx.doi.org/10.1071/cp10002.

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Carbon isotope discrimination (Δ) in flag leaf, grain and basal stem, grain yield (GY), and harvest index (HI), were determined in a collection of 20 bread wheat cultivars (landraces, released cultivars and advanced lines) in Yinchuan, located in the central region of the Ningxia region (North-west of China), in 2007 and 2008. In 2008, specific stem DW (SSDW) and carbohydrates, including water-soluble carbohydrate (WSC), non-water-soluble carbohydrates (NWSC) and total non-structural carbohydrate (TNSC) in stem were also measured. Relationships between GY, HI, SSDW, accumulation and mobilisati

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Vanden Heuvel, Justine E., and Martin C. Goffinet. "The Effects of Flood Initiation Timing and Water Temperature During Flooding on Nonstructural Carbohydrate Concentration and Anatomy of Cranberry." HortScience 43, no. 2 (2008): 338–45. http://dx.doi.org/10.21273/hortsci.43.2.338.

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The objective of this research was to determine the effect of water temperature during spring and fall floods on nonstructural carbohydrate concentration and anatomy/morphology of ‘Stevens’ and ‘Early Black’ cranberry vines. Potted vines of each cultivar were subjected to either a simulated 1-month late water (LW) flood in the spring at either 11 or 21 °C or a simulated 1-week harvest flood in the fall at either 12 or 20 °C. Higher water temperature resulted in decreased total nonstructural carbohydrate concentration (TNSC) during the LW flood in both uprights (i.e., vertical shoots) and roots

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Adhikari, Sudipta, and Kaushik Banerjee. "Role of Trade Union on Labour Administration on its Associate’s Performance in TNSTC, Kumbakonam Division–I." International Journal on Recent Trends in Business and Tourism 06, no. 03 (2022): 27–35. http://dx.doi.org/10.31674/ijrtbt.2022.v06i03.003.

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The existence of a recognized and strong trade union is vital for an industrial process to run smoothly. Act 651, also called the Labor Act 2003, was formed to help, and act as a guide to maintain a peaceful relationship between the employees and the management. It becomes important to acknowledge the major role the Union Activities have for an organization. These roles include maintaining harmony among employers and employees of an industry; negotiating or dealing with employees; serving as a director and guide for the employees for directing their concerns; and other similar roles. Decisions

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Bhargava, D. S., and S. B. Sheldarkar. "Use of TNSAC in phosphate adsorption studies and relationships. Isotherm relationships and utility in the field." Water Research 27, no. 2 (1993): 325–35. http://dx.doi.org/10.1016/0043-1354(93)90092-v.

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Trinh, Terry, Kimberley Au, Arun V. Krishnan, et al. "Comparison of nab-paclitaxel, paclitaxel, and oxaliplatin-induced peripheral neuropathy: a cross-sectional cohort study." Acta Oncologica 64 (April 15, 2025): 527–33. https://doi.org/10.2340/1651-226x.2025.42935.

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Background and purpose: There remains limited evidence regarding the relative neurotoxic potential of nab-paclitaxel long-term. This cross-sectional matched cohort study aimed to compare the severity and natural history of chemotherapy-induced peripheral neuropathy (CIPN) between patients treated with nab-paclitaxel and patients treated with oxaliplatin or paclitaxel using a suite of clinical, patient reported, and neurophysiological assessments. Patients and methods: CIPN assessments included the total neuropathy score (TNSc), grooved pegboard assessment, sensory assessments (grating orientat

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Gamas, Pascal, and Nancy L. Craig. "Purification and characterization of TnsC, a Tn7 transposition protein that binds ATP and DNA." Nucleic Acids Research 20, no. 10 (1992): 2525–32. http://dx.doi.org/10.1093/nar/20.10.2525.

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Bhargava, D. S., and S. B. Sheldarkar. "Use of TNSAC in phosphate adsorption studies and relationships. Effects of adsorption operating variables and related relationships." Water Research 27, no. 2 (1993): 313–24. http://dx.doi.org/10.1016/0043-1354(93)90091-u.

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Choi, K. Y., J. M. Spencer, and N. L. Craig. "The Tn7 transposition regulator TnsC interacts with the transposase subunit TnsB and target selector TnsD." Proceedings of the National Academy of Sciences 111, no. 28 (2014): E2858—E2865. http://dx.doi.org/10.1073/pnas.1409869111.

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Bhargava, D. S., and S. B. Sheldarkar. "Use of TNSAC in phosphate adsorption studies and relationships. Literature, experimental methodology, justification and effects of process variables." Water Research 27, no. 2 (1993): 303–12. http://dx.doi.org/10.1016/0043-1354(93)90090-5.

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Ronning, Donald R., Ying Li, Zhanita N. Perez, et al. "The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA." EMBO Journal 23, no. 15 (2004): 2972–81. http://dx.doi.org/10.1038/sj.emboj.7600311.

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