Academic literature on the topic 'Tocolyse'

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Journal articles on the topic "Tocolyse"

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Barrier, G. "Magnésium et tocolyse." Annales Françaises d'Anesthésie et de Réanimation 4, no. 5 (January 1985): 458. http://dx.doi.org/10.1016/s0750-7658(85)80285-9.

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Carrez, S., and J. Sibiude. "Tocolyse d’entretien par nifédipine." Gynécologie Obstétrique & Fertilité 41, no. 7-8 (July 2013): 465–66. http://dx.doi.org/10.1016/j.gyobfe.2013.05.005.

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Durlach, J., M. Bara, and A. Guiet-Bara. "Bêta-mimétiques, magnésium et tocolyse." Annales Françaises d'Anesthésie et de Réanimation 4, no. 4 (January 1985): 391. http://dx.doi.org/10.1016/s0750-7658(85)80119-2.

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Rozenberg, P. "Le point sur la tocolyse." Journal de Gynécologie Obstétrique et Biologie de la Reproduction 44, no. 8 (October 2015): 752–59. http://dx.doi.org/10.1016/j.jgyn.2015.06.015.

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Carbillon, L. "Tocolyse dans les situations pathologiques particulières." Journal de Gynécologie Obstétrique et Biologie de la Reproduction 33, no. 1 (February 2004): 45–50. http://dx.doi.org/10.1016/s0368-2315(04)96664-1.

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Gondry, J. "Tocolyse de première intention par atosiban." Gynécologie Obstétrique & Fertilité 33, no. 4 (April 2005): 260–62. http://dx.doi.org/10.1016/j.gyobfe.2005.03.014.

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Tsatsaris, V., F. Goffinet, B. Carbonne, G. Abitayeh, and D. Cabrol. "Tocolyse de première intention par nifédipine." Gynécologie Obstétrique & Fertilité 33, no. 4 (April 2005): 263–65. http://dx.doi.org/10.1016/j.gyobfe.2005.03.015.

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Maisonneuve, E., and B. Carbonne. "Tocolyse d’entretien par les inhibiteurs calciques." Journal de Gynécologie Obstétrique et Biologie de la Reproduction 44, no. 4 (April 2015): 357–62. http://dx.doi.org/10.1016/j.jgyn.2014.12.009.

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Hannah, W. J. "Une tocolyse efficace—Notre quête du Saint-Graal." Journal SOGC 17, no. 11 (November 1995): 1063–66. http://dx.doi.org/10.1016/s0849-5831(16)30181-1.

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Bekkari, Y., J. Lucas, T. Beillat, A. Chéret, and M. Dreyfus. "Tocolyse par la nifédipine. Utilisation en pratique courante." Gynécologie Obstétrique & Fertilité 33, no. 7-8 (July 2005): 483–87. http://dx.doi.org/10.1016/j.gyobfe.2005.05.020.

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Dissertations / Theses on the topic "Tocolyse"

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Killian, Hélène Hullen Christian Siegrist Sophie. "HAD obstétricale indications et rôles du médecin généraliste /." [S.l.] : [s.n.], 2007. http://www.scd.uhp-nancy.fr/docnum/SCDMED_T_2007_KILLIAN_HELENE.pdf.

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Doret, Muriel. "Le travail prématuré spontané : identification précoce par l'électromyogramme utérin et inhibition par le rofecoxib (un inhibiteur de la cyclooxygénase-2) et par les associations de tocolytiques : approche expérimentale chez la rate gestante." Lyon 1, 2006. http://www.theses.fr/2006LYO10062.

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L'objectif de ce travail était d'évaluer de nouvelles approches diagnostique et thérapeutique du travail prématuré chez la rate gestante. L'étude de l'électromyogramme utérin a montré que l'analyse spectrale permettait d'identifier précocement le travail prématuré, bien avant l'augmentation de la pression intra-utérine. Au cours du travail prématuré, la cyclooxydenase-2 joue un rôle central dans la synthèse des prostaglandines. Elle est donc une cible thérapeutique privilégiée pour inhiber le travail prématuré. Nous avons montré que le rofecoxib, in inhibiteur spécifique de la cyclooxydenase-2, a un eeffet tocolytique comparable aux inhibiteurs calciques in vitro et in vivo, mais plus puissant que l'indométacine, la ritodrine, et l'atosiban.
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Lorthe, Elsa. "Rupture prématurée des membranes avant 33 semaines d'aménorrhée : prise en charge anténatale et déterminants du pronostic de l'enfant." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066350/document.

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La rupture prématurée des membranes avant terme (RPMAT) est une complication de la grossesse responsable d’une importante morbi-mortalité périnatale. La prise en charge anténatale vise à réduire les conséquences délétères de cette pathologie, liées à l’inflammation intra-utérine et à la prématurité, à la fois pour la mère et pour l’enfant. L’objectif de cette thèse était d’étudier les déterminants obstétricaux du pronostic de L’enfant prématuré né dans un contexte de RPMAT, à partir des données de la cohorte EPIPAGE 2. Nous avons d’abord évalué l’impact de la durée de latence, comprise entre la RPMAT et l’accouchement, sur le pronostic néonatal. Nos résultats montrent que pour un âge gestationnel de naissance donné, la durée de latence après une RPMAT entre 24 et 32 SA n’est pas associée à la survie ou à la survie sans morbidité sévère. Le principal déterminant du pronostic néonatal est l’âge gestationnel à la naissance. Nous avons ensuite étudié la tocolyse, un traitement médicamenteux largement utilisé après une RPMAT dans le but de prolonger la grossesse. L’administration d’une tocolyse après une RPMAT n’est associée ni à l’amélioration de la survie sans morbidité du prématuré, ni à la prolongation de la grossesse. Enfin, une analyse descriptive des cas de RPMAT entre 22 et 25 SA montre qu’à ces âges gestationnels extrêmes, la RPMAT est associée à un risque élevé de mortalité périnatale et de morbidité à court et à long terme, avec de grandes variations selon l’âge gestationnel à la rupture. Nos travaux fournissent des informations pertinentes pour les équipes médicales et les femmes enceintes et questionnent certaines pratiques obstétricales, notamment l’administration d’une tocolyse après une RPMAT. Ils soulèvent des questions qui feront l’objet de nouveaux projets de recherche, en particulier un essai contrôlé randomisé sur la tocolyse après RPMAT, financé par le PHRC-N 2016 (essai TOCOPROM)
Preterm premature rupture of membranes (PPROM) is a complication of pregnancy responsible for significant perinatal mortality and morbidity. Antenatal management aims to reduce adverse consequences, relating to intrauterine inflammation and prematurity, for both mother and child. This thesis aimed to study obstetric determinants impacting the outcome of preterm babies born following PPROM, using data from the EPIPAGE 2 cohort. We first evaluated the impact of latency duration, i.e. the time from PPROM to delivery, on neonatal prognosis. For a given gestational age at birth, latency duration after PPROM at 24-32 weeks' gestation was not associated with survival or survival without severe morbidity. The principal determinant of neonatal prognosis was gestational age at birth. We then studied tocolysis, a treatment widely used after PPROM to prolong pregnancy. Administration of tocolysis after PPROM was not associated with either improved survival without morbidity of the preterm infant or prolongation of pregnancy. Finally, a descriptive analysis of cases of PPROM occurring at 22-25 weeks’ gestation demonstrated that, at these extreme gestational ages, PPROM was associated with high risks of perinatal mortality and short- and long-term morbidity, with large variations according to gestational age at rupture. Our work provides relevant information for medical teams and pregnant women and questions some obstetric practices, particularly the use of tocolysis after PPROM. They raise issues that will be the subject of future research projects, specifically a randomized controlled trial on tocolysis after PPROM, already funded by PHRC-N 2016 (TOCOPROM trial)
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Dupouy, Hélène. "Médicaments tocolytiques : intérêt de la nifédipine." Bordeaux 2, 1996. http://www.theses.fr/1996BOR2P077.

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Rouget, Céline. "Le récepteur β3-adrénergique du muscle lisse utérin humain : une cible potentielle d'agents tocolytiques." Paris 5, 2004. http://www.theses.fr/2004PA05P614.

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La prématurité reste la principale cause de mortalité et morbidité néonatales dans les pays industrialisés. Les stratégies de prise en charge médicale restent limitées et relativement inefficaces. Parmi les différentes mesures à mettre en place pour tenter de diminuer le taux de prématurité et les complications aigues ou retardées affectant le nouveau-né prématuré, le développement d'outils pharmacologiques nouveaux visant à traiter les dysfonctionnements de la contractilité utérine est indispensable. Nous nous sommes intéressés au récepteur b3-adrénergique et à ses agonistes connus pour avoir un effet myorelaxant sur le muscle lisse utérin, le myomètre. L'objectif de notre travail a été de poursuivre la caractérisation pharmacologique du récepteur b3-adrénergique dans le myomètre humain, d'une part en étudiant l'influence de la grossesse sur l'expression de ce récepteur et d'autre part en explorant les phénomènes de désensibilisation pouvant l'affecter. L'ensemble de nos résultats permet ainsi d'envisager le développement clinique d'agonistes sélectifs du récepteur b3-adrénergique dans la prise en charge pharmacologique de la menace d'accouchement prématuré
The preterm birth represents the leading cause of neonatal mortality and morbidity in developed countries. The strategies for medical management remain restricted and relatively inefficient. Amongst different actions undertaken to reduce preterm birth and health problems of preterm neonates, the development of new pharmacological tools to treat uterine contractility dysfunction is essential. We were interested in the b3-adrenoceptor and its agonists known to have myorelaxant properties on the uterus smooth muscle, the myometrium. The aim of our work consisted in the pharmacological characterisation of the b3-adrenoceptor in the human myometrium, on the one hand in studying the influence of pregnancy on the expression of this receptor and on the other hand, by exploring the desensitisation phenomenon which can affect it. Our results give arguments in favour of clinical development of selective b3- adrenoceptor agonists in the pharmacological treatment of preterm labour
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Barets, Frédéric. "Œdèmes aigus du poumon et grossesse gémellaire : à propos de 4 cas observés à la Réunion aux décours de traitements tocolytiques par bêtamimétiques." Bordeaux 2, 1998. http://www.theses.fr/1998BOR2M041.

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Rihana, Sandy. "Modélisation de l'activité électrique utérine." Compiègne, 2008. http://www.theses.fr/2008COMP1742.

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Durant ces dernières décennies, l'activité électrique utérine origine des contractions menant à l'accouchement constitue une étude de recherche primordiale pour la prévention et pour la détection des accouchements prématurés. La modélisation mathématique et la simulation informatique sont devenues des outils indispensables pour la compréhension de différents phénomènes électrophysiologiques afin de prédire, et d'agir en cas d'anomalie. Sachant que le contrôle de l'excitabilité utérine s'avère avoir des conséquences thérapeutiques importantes, nous avons choisi de débuter le modèle à l'échelle cellulaire. L'analyse dynamique de ce modèle a permis de montrer l'efficacité de certains traitements tocolytiques tels que les bloqueurs des canaux calciques et les ouvreurs des canaux potassiques. Le contrôle de la contractilité utérine ne se limite pas au niveau cellulaire mais s'étend aussi au niveau tissulaire. Nous avons démontré comment un modèle de propagation biophysique permet de reproduire le couplage électrique réduit entre les cellules en début de grossesse et le couplage fort et synchronisé à l'approche du terme. Cette propagation a permis d'estimer un électromyogramme utérin de surface. Ce travail de thèse, quoique innovant et intéressant reste dans une première étape préliminaire. Il en porte en lui de futurs axes de recherches et de développement pluridisciplinaires prometteurs, dans l'objectif de fournir un modèle numérique de l'activité électrique utérine, contribuant à la compréhension de phénomènes physiologiques et à la prédiction d'accouchement prématuré
It is hypothesized that uterine electrical activity is efficiently correlated to the uterine contractions appearance. Once, forceful contractions appear, delivery is near. Therefore, the understanding of the genesis and of the propagation of the uterine electrical activity may provide an efficient tool to diagnosis preterm labour. Moreover, the control of uterine excitability seems to have important therapeutic consequences in controlling preterm labour. Modelling the electrical activity in uterine tissue is an important step for the understanding of physiological uterine contractile mechanisms. It would permit to reconstruct the uterine EMG. This work presents an electrophysiological model of the uterine cell that incorporates ion channel models at the cell level. The dynamical analysis of the uterine cell model allows a better apprehension of the main physiological effects on the cell's reponse. The cellular electrical activity will be integrated in a two dimension model, represented by the reaction diffusion equations, and will serve to the spatio-temporel integration at the uterine level for EMG reconstruction. This model validates some key physiological hypotheses considering uterine excitability and propagation
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Panter, Katerine Ruth. "Cyclooxygenase expression and inhibition and tocolysis in preterm labour." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391614.

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Grant, Therese Marie. "The management of preterm labor with tocolytics in general obstetric practice /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/10867.

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Mohanna, Magdi. "Preterm birth : evaluation of an intervention programme comprising risk factor scoring, fetal fibronectin testing and nifedipine tocolysis." Thesis, Keele University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341303.

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Introduction Neonatal mortality and morbidity from premature birth are still a major concern despite significant advances in perinatal medicine. Objective of the study The primary aim of the study was to establish the feasibility of accurately identifying a cohort of vvomen at increased risk of preterm birth using a modified risk assessment score and fetal fibronectin testing in order to undertake a pilot randomised placebo-controlled trial of nifedipine as a tocolytic. Methodology A population of pregnant women was screened prospectively between 24 and 34 weeks of gestation using a modified risk assessment system. Women identified as high-risk for preterm birth were then tested with fetal fibronectin. Those testing positive were randomised to either nifedipine or placebo. The study at this point was randomised, placebo-controlled and double-blind. Measures of outcome were compared for babies of trial vvomen with high-risk women who withheld consent. Main outcome measures Delivery before 34 weeks, neonatal death, admission to the Special Care Baby Unit (SCBU), chronic lung disease and major cerebral abnormality on ultrasound scan constituted the main measures of outcome. Results Five hundred and thirty four vvomen were identified as high-risk for preterm birth. One hundred and forty two women agreed to participate in the study. Forty nine women delivered before 37 weeks' gestation. The system was sensitive in predicting preterm birth before 34 weeks of gestation and within one week of testing for fetal fibronectin in symptomatic women. Babies of non-consenting mothers fared better overall than babies of the trial women. Conclusion Risk factor scoring and fetal fibronectin testing are useful screening tools that can predict preterm delivery. This sysytem can be clinically useful in the management of preterm labour or women at increased risk for preterm birth. There was no impact on the neonatal mortality or morbidity.
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Books on the topic "Tocolyse"

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Kuhn, Walther, and Gerhard G. Grospeitsch. Tocolysis: Treatment of Premature Labor With B2-Sympathicomimetics. Thieme-Stratton Corp, 1985.

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Doumouchtsis, Stergios K., S. Arulkumaran, Eleftheria L. Chrysanthopoulou, Stergios K. Doumouchtsis, Sambit Mukhopadhyay, Kostis I. Nikolopoulos, Christiana Nygaard, et al. Intrapartum procedures and complications. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199651382.003.0005.

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This chapter discusses the diagnosis of labour, and describes what to do in the case of cord prolapse, abnormal fetal heart rate patterns in labour, continuous abdominal pain in labour, instrumental delivery for fetal distress in the second stage of labour, shoulder dystocia, acute tocolysis, symphysiotomy and destructive operations, along with twin delivery, breech delivery, abnormal lie or presentation in labour, and anaesthetic complications on the labour ward.
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1933-, Tejani Nergesh, ed. Obstetrical events and developmental sequelae. 2nd ed. Boca Raton: CRC Press, 1994.

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Book chapters on the topic "Tocolyse"

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Matsuda, Yoshio. "Prevention and Tocolytic Agent: Hydration, Bed Rest, Ritodrine, and Special Comments on Long-Term Tocolysis." In Preterm Labor and Delivery, 107–14. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9875-9_10.

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C., John, John P., and Stephen Jones. "Uterine Contraction Monitoring, Maintenance Tocolysis, and Preterm Birth." In Preterm Birth - Mother and Child. InTech, 2012. http://dx.doi.org/10.5772/26897.

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Pugh, Meredith, and Tina Hartert. "Chest diseases in pregnancy." In Oxford Textbook of Medicine, edited by Catherine Nelson-Piercy, 2613–18. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0270.

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Respiratory changes in pregnancy include an increase in tidal volume and minute ventilation, leading to a primary respiratory alkalosis. This chapter examines the various chest conditions arising in pregnancy—these include: amniotic fluid embolism—unique to pregnancy; venous air embolism—a rare condition that can occur in pregnancy; venous and pulmonary thromboembolism—pregnancy is a risk factor; pulmonary oedema—this can be caused by heart disease, as in the non-pregnant state, but it can also be associated with pre-eclampsia or HELPP syndrome and be induced by tocolysis; aspiration; varicella pneumonia—a potentially devastating complication of primary varicella-zoster virus infection; and influenza, which is associated with increased maternal morbidity.
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Fratianni, Alessandra, Gianfranco Panfili, and Raimondo Cubadda. "Carotenoids, Tocols, and Retinols during the Pasta-Making Process." In Processing and Impact on Active Components in Food, 309–17. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-404699-3.00037-8.

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Shendy, Maged, Hend Hendawy, Amr Salem, Ibrahim Alatwi, and Abdurahman Alatawi. "Preterm Labour." In Midwifery [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96049.

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Preterm delivery is defined as delivery before 37 weeks completed gestation. It represents a major cause of neonatal morbidity and mortality and accounts for 5–10% of all deliveries. Cervical length assessment between 16–24 weeks and positive fetal fibronectin beyond 21 weeks gestation are proved to useful tools in prediction of preterm labour. Treating asymptomatic bacteruia and bacterial vaginosis in high-risk women reduces the incidence of preterm labour. Cervical cerclage is recommended to reduce the incidence of preterm birth in women with 2nd trimester losses and those with cervical length of 25 mm or less on transvaginal ultrasound between 16–24 weks gestation. Atosiban and nifidipine are currently the agents of choice in tocolysis. Antenal steriods in womens with threating preterm labour reduces the perinatal morbidties. Magnisum sulphate role is established for neuroprotection especially in extreme gestations between 24–30 weeks. Vaginal delivery is mode of choice for delivery with consideration to avoid fetal blood sampling, fetal scalp electrodes and ventouse prior to 34 weeks gestations. Caesarean section is considered for obstetric reasons that guide labour management at term.
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Conference papers on the topic "Tocolyse"

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RajKumar, Ashwin, Jeffrey Karsdon, Frederick Naftolin, and Vikram Kapila. "Electrical Inhibitor for Tocolysis." In 2020 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/dmd2020-9075.

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Abstract Preterm birth (PTB) is one of the leading causes of neonatal morbidities and mortalities. Limited methods are available to physicians for mitigating PTB, thus posing an urgent need to develop effective methods for its prevention. In prior research, a benchtop electronic uterine control device (EUCD) was developed for tocolysis through injection of current pulses. However, the benchtop version is wall tethered and constrains patients to hospitals, i.e., it is unsuitable for deployment in outpatient or home settings. This paper focuses on the development of a mechatronics-based, low-cost, battery-powered, portable, and reproducible EUCD, which is suitable for use in home and clinical environments. The developed mechatronic version is validated for electrical performance with resistive load-tests, which indicate that the mechatronic device can generate current pulses similar to the existing benchtop EUCD. Furthermore, the signals generated from the device are evaluated for repeatability using coefficient of variation (CV) analysis and the results indicate that the mechatronic version can produce repeatable frequency (1–100Hz), amplitude (1–17mA), and pulse width (1–120ms) modulated current signals. An internet of medical things (IoMT) methodology is discussed to enable seamless transition of the developed device from a clinical environment to a home-based setting for remote use by the patients.
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Gallardo, Jade, Sandeep Chennadi, and Joshua Rosenberg. "Pulmonary Edema After Magnesium Sulfate Tocolysis In Twin Gestation Associated Preterm Labor." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5941.

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Huang, Yan, Jonathan Katz, and David Evans. "Quid-Pro-Quo-tocols: Strengthening Semi-honest Protocols with Dual Execution." In 2012 IEEE Symposium on Security and Privacy (SP) Conference dates subject to change. IEEE, 2012. http://dx.doi.org/10.1109/sp.2012.43.

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