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1

Sabane, Anand, Amol Patil, Vinit Swami, and Preethi Nagarajan. "Biology of Tooth Movement." British Journal of Medicine and Medical Research 16, no. 12 (2016): 1–10. http://dx.doi.org/10.9734/bjmmr/2016/27019.

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2

PC, Lekic. "Molecular Biology of Orthodontic Tooth Movement." jdoh 1, no. 1 (2019): 1–5. http://dx.doi.org/10.17303/jdoh.2013.1.101.

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3

Shivalinga, BM, H. Jyothikiran, and Vishal Devendrakumar Patel. "Enroute through Bone: Biology of Tooth Movement." World Journal of Dentistry 3, no. 1 (2012): 55–59. http://dx.doi.org/10.5005/jp-journals-10015-1128.

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ABSTRACT Biology of orthodontic tooth movement has always been an interesting field of orthodontist. Orthodontic tooth movement is divided into different phases and number of theories has been given for it, at present most of them are invalid. Gene-directed protein synthesis, modification and integration form the essence of all life processes, including OTM. Bone adaptation to orthodontic force depends on normal osteoblast and osteoclast genes that correctly express needed proteins at the right time and places. Prostaglandins, cytokines and growth factors play an important role in OTM. How to
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4

Krishnan, Vinod, Sajan V. Nair, Ambili Ranjith, and Ze'ev Davidovitch. "Research in Tooth Movement Biology: The Current Status." Seminars in Orthodontics 18, no. 4 (2012): 308–16. http://dx.doi.org/10.1053/j.sodo.2012.06.009.

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5

Norton, Louis A. "Fundamental principles of the biology of tooth movement." Seminars in Orthodontics 6, no. 3 (2000): 139–44. http://dx.doi.org/10.1053/sodo.2000.8080.

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6

Li, Yina, Laura A. Jacox, Shannyn H. Little, and Ching-Chang Ko. "Orthodontic tooth movement: The biology and clinical implications." Kaohsiung Journal of Medical Sciences 34, no. 4 (2018): 207–14. http://dx.doi.org/10.1016/j.kjms.2018.01.007.

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7

Gorski, Jeffrey P., and Sandy C. Marks. "Current Concepts of the Biology of Tooth Eruption." Critical Reviews in Oral Biology & Medicine 3, no. 3 (1992): 185–206. http://dx.doi.org/10.1177/10454411920030030201.

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Tooth eruption is defined as the movement of a tooth from its site of development within the jaws to its position of function within the oral cavity. We present a critical review of evidence for the mechanisms and regulation of the intraosseous and supraosseous phases of eruption, with an emphasis upon the canine premolar model studied by the authors. Analyses at different stages of premolar eruption indicate that selective fragmentation of dental follicle protein DF-95 correlates with the presence of elevated levels of follicular collagenase and stromelysin, and with the onset of premolar mov
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8

Choi, Hyung-Joo, Dong-Yeol Lee, and Tae-Woo Kim. "Dynamics of Alloplastic Bone Grafts on an Early Stage of Corticotomy-Facilitated Orthodontic Tooth Movement in Beagle Dogs." BioMed Research International 2014 (2014): 1–13. http://dx.doi.org/10.1155/2014/417541.

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Alveolar augmented corticotomy is effective in accelerating orthodontic tooth movement, but the effect only lasts for a relatively short time. Therefore, the purpose of this study was to investigate the underlying biology of the immediate periodontal response to orthodontic tooth movement after a corticotomy with alloplastic bone grafts. The results demonstrated that measurable tooth movement began as early as 3 days after the intervention in beagle dogs. Based on the results and histological findings, augmented corticotomy-facilitated orthodontic tooth movement might enhance the condition of
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9

Dolce, Calogero, J. Scott Malone, and Timothy T. Wheeler. "Current concepts in the biology of orthodontic tooth movement." Seminars in Orthodontics 8, no. 1 (2002): 6–12. http://dx.doi.org/10.1053/sodo.2002.28165.

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10

Lobb, W. K. "Current concepts in the biology of orthodontic tooth movement." Yearbook of Dentistry 2007 (January 2007): 199–200. http://dx.doi.org/10.1016/s0084-3717(08)70456-2.

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11

Masella, Richard S., and Malcolm Meister. "Current concepts in the biology of orthodontic tooth movement." American Journal of Orthodontics and Dentofacial Orthopedics 129, no. 4 (2006): 458–68. http://dx.doi.org/10.1016/j.ajodo.2005.12.013.

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12

Sun, Yuqing, Jingfei Fu, Feiran Lin, et al. "Force-Induced Nitric Oxide Promotes Osteogenic Activity during Orthodontic Tooth Movement in Mice." Stem Cells International 2022 (September 6, 2022): 1–10. http://dx.doi.org/10.1155/2022/4775445.

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Objectives. The aim of this study was to investigate the effect of nitric oxide (NO) on orthodontic tooth movement and the regulatory effect on bone formation. Design. A mouse orthodontic tooth movement model was established to measure the level of releasing NO. Besides, orthodontic tooth movement distance and the bone formation in the tension side of the orthodontic tooth were also analyzed. In vitro, human periodontal ligament stem cells (hPDLSCs) were cultured under tensile force stimulation. The production of NO and the expression level of nitric oxide synthase (NOS) were detected after me
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13

Hilbert, David Andreas, Svenja Memmert, Jana Marciniak, and Andreas Jäger. "Molecular biology of periodontal ligament fibroblasts and orthodontic tooth movement." Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie 80, no. 6 (2019): 336–47. http://dx.doi.org/10.1007/s00056-019-00195-5.

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14

Perinetti, Giuseppe. "The friction concept must acknowledge the biology of tooth movement." American Journal of Orthodontics and Dentofacial Orthopedics 134, no. 4 (2008): 468–69. http://dx.doi.org/10.1016/j.ajodo.2008.08.007.

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15

Sugimori, Tadasu, Masaru Yamaguchi, Jun Kikuta, Mami Shimizu, and Shinichi Negishi. "Micro-Osteoperforations Accelerate Tooth Movement without Exacerbating the Progression of Root Resorption in Rats." Biomolecules 14, no. 3 (2024): 300. http://dx.doi.org/10.3390/biom14030300.

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A recent study reported that micro-osteoperforations (MOPs) accelerated tooth movement by activating alveolar bone remodeling. However, very little is known about the relationship between MOPs and external apical root resorption during orthodontic treatment. In this study, in order to investigate the mechanism through which MOPs accelerate tooth movement without exacerbating the progression of root resorption, we measured the volume of the resorbed root, and performed the terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick-end labeling (TUNEL) method on exposed MOPs during ex
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16

Andhare, Pushkar, Sanjeev Datana, Shiv Agarwal, SS Chopra, and ID Roy. "Assessment of changes in maxillary dentoalveolar complex following retraction and intrusion of maxillary anterior teeth in mixed Indian population." Journal of Contemporary Orthodontics 7, no. 2 (2023): 125–32. http://dx.doi.org/10.18231/j.jco.2023.021.

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The biology of tooth movement implies to selective resorption and deposition of the alveolar bone during orthodontic tooth movement. The controversy about "tooth movement through bone" and "tooth movement with bone” is still not settled. The cortices of the alveolar bone are considered boundaries of the alveolar complex that limit the orthodontic tooth movement. The present study evaluated the change in these limits of maxillary dentoalveolar complex post-retraction and intrusion of maxillary anterior teeth.: CBCT data of 15 subjects was assessed to primarily measure the changes in thickness,
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17

Kanzaki, Hiroyuki, and Yoshiki Nakamura. "Orthodontic tooth movement and HMGB1." Journal of Oral Biosciences 60, no. 2 (2018): 49–53. http://dx.doi.org/10.1016/j.job.2018.03.002.

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18

Yamauchi, Taisuke, Megumi Miyabe, Nobuhisa Nakamura, et al. "Impacts of Glucose-Dependent Insulinotropic Polypeptide on Orthodontic Tooth Movement-Induced Bone Remodeling." International Journal of Molecular Sciences 23, no. 16 (2022): 8922. http://dx.doi.org/10.3390/ijms23168922.

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Glucose-dependent insulinotropic polypeptide (GIP) exerts extra-pancreatic effects via the GIP receptor (GIPR). Herein, we investigated the effects of GIP on force-induced bone remodeling by orthodontic tooth movement using a closed-coil spring in GIPR-lacking mice (GIPRKO) and wild-type mice (WT). Orthodontic tooth movements were performed by attaching a 10-gf nickel titanium closed-coil spring between the maxillary incisors and the left first molar. Two weeks after orthodontic tooth movement, the distance of tooth movement by coil load was significantly increased in GIPRKO by 2.0-fold compar
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19

Yamashiro, T., H. Kabuto, T. Fukunaga, N. Ogawa, and T. Takano-Yamamoto. "Medullary monoamine levels during experimental tooth movement." Brain Research 878, no. 1-2 (2000): 199–203. http://dx.doi.org/10.1016/s0006-8993(00)02655-x.

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20

Milosevic-Jovcic, Nadezda, Amila Vujacic, Aleksandra Konic, Jasna Pavlovic, Vera Todorovic, and Marija Glibetic. "The role of cytokines in orthodontic tooth movement." Srpski arhiv za celokupno lekarstvo 140, no. 5-6 (2012): 371–78. http://dx.doi.org/10.2298/sarh1206371m.

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One of the most important breakthroughs in the understanding of bone biology was the identification of the role of cytokines in bone remodelling including the alveolar bone exposed to the effect of mechanical forces during orthodontic treatment. Since bone remodelling is associated, in its early phase, with inflammation of the surrounding tissue, the hypothesis has been suggested on the role of proinflammatory cytokines in the process of bone remodelling, primarily IL-1?, IL-6 and TNF- ?. These cytokines function as response mediators in the acute phase of inflammation, as well as in the proce
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21

Kirschneck, Christian, Nadine Straßmair, Fabian Cieplik та ін. "Myeloid HIF1α Is Involved in the Extent of Orthodontically Induced Tooth Movement". Biomedicines 9, № 7 (2021): 796. http://dx.doi.org/10.3390/biomedicines9070796.

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During orthodontic tooth movement, transcription factor hypoxia-inducible factor 1α (HIF1α) is stabilised in the periodontal ligament. While HIF1α in periodontal ligament fibroblasts can be stabilised by mechanical compression, in macrophages pressure application alone is not sufficient to stabilise HIF1α. The present study was conducted to investigate the role of myeloid HIF1α during orthodontic tooth movement. Orthodontic tooth movement was performed in wildtype and Hif1αΔmyel mice lacking HIF1α expression in myeloid cells. Subsequently, µCT images were obtained to determine periodontal bone
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22

Alhashimi, Najat, Lars Frithiof, Pongsri Brudvik, and Moiz Bakhiet. "Chemokines Are Upregulated During Orthodontic Tooth Movement." Journal of Interferon & Cytokine Research 19, no. 9 (1999): 1047–52. http://dx.doi.org/10.1089/107999099313271.

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23

Choi, Kwang-Hyo, Dae-Won Kim, Suk Keun Lee, Seong-Gon Kim, and Tae-Woo Kim. "The Administration of 4-Hexylresorcinol Accelerates Orthodontic Tooth Movement and Increases the Expression Level of Bone Turnover Markers in Ovariectomized Rats." International Journal of Molecular Sciences 21, no. 4 (2020): 1526. http://dx.doi.org/10.3390/ijms21041526.

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Surgical methods for accelerating orthodontic tooth movement are limited by possible damage to the tooth root and patient discomfort. 4-Hexylresorcinol (4HR) has been shown to increase bone remodeling and may potentially facilitate tooth movement. This study investigated the (1) effect of 4HR administration on osteoblast-like cells and (2) effect of 4HR administration on tooth movement in ovariectomized rats. Saos-2 cells were treated with either 4HR or solvent (control). Protein expression levels were investigated 2, 8, and 24 h after treatment. Thirty ovariectomized Sprague-Dawley rats were
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24

Cadenas de Llano-Pérula, M., RM Yañez-Vico, E. Solano-Reina, JC Palma-Fernandez, and A. Iglesias-Linares. "Effectiveness of Biology-Based Methods for Inhibiting Orthodontic Tooth Movement. A Systematic Review." Journal of Clinical Pediatric Dentistry 41, no. 6 (2017): 494–502. http://dx.doi.org/10.17796/1053-4628-41.6.14.

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Introduction: Several experimental studies in the literature have tested different biology-based methods for inhibiting or decreasing orthodontic tooth movement (OTM) in humans. This systematic review investigated the effects of these interventions on the rate of tooth movement. Study design: Electronic [MedLine; SCOPUS; Cochrane Library; OpenGrey;Web of Science] and manual searches were conducted up to January 26th, 2016 in order to identify publications of clinical trials that compared the decreasing or inhibiting effects of different biology-based methods over OTM in humans. A primary outco
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25

Zheng, Junyi, Bowen Xu, and Kai Yang. "Autophagy Regulates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells Induced by Orthodontic Tension." Stem Cells International 2022 (October 4, 2022): 1–17. http://dx.doi.org/10.1155/2022/2983862.

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Tooth movement is the core of orthodontics. Osteogenesis of the tension side under orthodontic force has great significance on tooth movement and stability, which involves complex mechanical and biological signal transduction. However, the mechanism remains unclear. Through in vitro cell studies, we observed the increased expression levels of osteogenesis-related factors and autophagy-related factors during the osteogenic differentiation of mesenchymal stem cells induced by orthodontic force. The change trend of autophagy-related factors and osteogenesis-related factors is similar, which indic
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26

Alam, Mohammad K., and Balqees Alahmari. "Evaluation of Micro-Osteoperforations in Expediting Orthodontic Tooth Movement in Adult Patients." Journal of Pharmacy and Bioallied Sciences 16, Suppl 1 (2024): S527—S529. http://dx.doi.org/10.4103/jpbs.jpbs_844_23.

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ABSTRACT Background: Orthodontic tooth movement, the process of aligning teeth, can often be time-consuming, particularly in adult patients. Micro-osteoperforations (MOPs) have emerged as a potential technique to accelerate this process. Materials and Methods: A sample of 30 adult patients undergoing orthodontic treatment was selected. The patients were divided into two groups: an experimental group (EG) receiving MOPs and a control group (CG) without MOPs. Standard orthodontic treatment was administered to both groups. The rate of tooth movement was measured using digital models and recorded
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27

Zhou, Yonglong, Zhiping Song, Shibiao Chen, et al. "Mechanism of Catechol-O-methyltransferase Regulating Orofacial Pain Induced by Tooth Movement." BioMed Research International 2021 (October 23, 2021): 1–11. http://dx.doi.org/10.1155/2021/4229491.

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Objective. To explore the mechanism of catechol-O-methyltransferase (COMT) in tooth movement pain. Methods. The experimental groups were randomly allocated into the healthy control, sham operation, model, model+shCOMT experimental, model+shCOMT control, and model+COMT antagonist groups. A tooth movement pain model was established. The pain stimulation and behavior test were performed. The duration of grooming behavior was determined. The appropriate experimental force and duration for application were selected. COMT shRNA vector was constructed and packaged as adenovirus. The shCOMT adenovirus
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28

Krishnan, Vinod, Robert L. Sanford, and Ze’ev Davidovitch. "Tooth movement biology and laboratory experiments: How useful are they to orthodontic practitioners?" Seminars in Orthodontics 23, no. 4 (2017): 373–81. http://dx.doi.org/10.1053/j.sodo.2017.07.007.

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29

Alam, Mohammad K., Razan A. I. Alderaan, Shahad R. F. Alruwaili, and Dana S. A. Alanazi. "Comparing the Efficacy of Different Archwire Materials in Accelerating Orthodontic Tooth Movement." Journal of Pharmacy and Bioallied Sciences 16, Suppl 1 (2024): S537—S539. http://dx.doi.org/10.4103/jpbs.jpbs_851_23.

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ABSTRACT Background: Orthodontic treatment is commonly used to correct misaligned teeth and improve dental aesthetics and function. Archwires play a crucial role in this treatment by exerting forces on teeth, prompting them to shift into desired positions. Materials and Methods: For this experimental study, 60 participants requiring orthodontic treatment were selected and divided into three groups: Group A, treated with stainless steel archwires; Group B, treated with nickel-titanium archwires; and Group C, treated with beta-titanium archwires. Standardized orthodontic procedures were followed
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30

Gluhak-Heinrich, J., D. Pavlin, W. Yang, M. MacDougall, and S. E. Harris. "MEPE expression in osteocytes during orthodontic tooth movement." Archives of Oral Biology 52, no. 7 (2007): 684–90. http://dx.doi.org/10.1016/j.archoralbio.2006.12.010.

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31

Lin, Peng, Xin-xing Guo, Yi-ling Wang, Zhu-liang Wei, Hai-yan Xin, and Tong-bin Liu. "Inhibitory effect of baicalin on orthodontically induced inflammatory root resorption in rats." Journal of International Medical Research 48, no. 9 (2020): 030006052095507. http://dx.doi.org/10.1177/0300060520955070.

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Objective This study investigated the inhibitory effect of baicalin on orthodontically induced inflammatory root resorption in rats. Methods Forty-five male Wistar rats were randomly divided into three groups of 15 rats each. Fifty grams of force was used to establish an orthodontic tooth movement model. Baicalin (40 mg/kg) was locally injected into rats in the baicalin group at 3-day intervals; concurrently, normal saline was injected into rats in the negative control group. On the 21st day after orthodontic treatment, the tooth movement distance and root resorption area ratio were measured.
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32

Brockhaus, Julia, Rogerio B. Craveiro, Irma Azraq, et al. "In Vitro Compression Model for Orthodontic Tooth Movement Modulates Human Periodontal Ligament Fibroblast Proliferation, Apoptosis and Cell Cycle." Biomolecules 11, no. 7 (2021): 932. http://dx.doi.org/10.3390/biom11070932.

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Human Periodontal Ligament Fibroblasts (hPDLF), as part of the periodontal apparatus, modulate inflammation, regeneration and bone remodeling. Interferences are clinically manifested as attachment loss, tooth loosening and root resorption. During orthodontic tooth movement (OTM), remodeling and adaptation of the periodontium is required in order to enable tooth movement. hPDLF involvement in the early phase-OTM compression side was investigated for a 72-h period through a well-studied in vitro model. Changes in the morphology, cell proliferation and cell death were analyzed. Specific markers o
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33

Nagappan, Nagappan, Thomson Mariadasan Dcruz, Archana Loganathan, et al. "Evaluation of Dentist Perception of Platelet Rich Plasma (PRP) for Accelerated Tooth Movement - Cross Sectional Survey." Journal of Pharmacy and Bioallied Sciences 16, Suppl 2 (2024): S1591—S1593. http://dx.doi.org/10.4103/jpbs.jpbs_1187_23.

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ABSTRACT The current survey was conducted to assess the knowledge, awareness and perception of platelet-rich plasma (PRP) on accelerated tooth movement among dentist present in the state of Tamil Nadu. Tamil Nadu dentists were the subjects of the cross-sectional questionnaire survey. 500 participants completed self-administered questionnaires about their knowledge, awareness, and perception of PRP’s effect on accelerated tooth movement. The Statistical Package for the Social Sciences (SPSS) (V 22.0) was used to do the statistical analysis. It computed the frequency distribution.The result show
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34

Şen, Sinan, and Ralf Erber. "Neuronal Guidance Molecules in Bone Remodeling and Orthodontic Tooth Movement." International Journal of Molecular Sciences 23, no. 17 (2022): 10077. http://dx.doi.org/10.3390/ijms231710077.

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During orthodontic tooth movement, mechanically induced remodeling occurs in the alveolar bone due to the action of orthodontic forces. The number of factors identified to be involved in mechanically induced bone remodeling is growing steadily. With the uncovering of the functions of neuronal guidance molecules (NGMs) for skeletal development as well as for bone homeostasis, NGMs are now also among the potentially significant factors for the regulation of bone remodeling during orthodontic tooth movement. This narrative review attempts to summarize the functions of NGMs in bone homeostasis and
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35

Ambroise, Marie A., Tara V. Avirachan, S. Brijesh, Arun Bosco Jerald, Mahima Anilkumar Sreelatha, and Sukumar V. Lipare. "Accelerated Orthodontic Treatment using Biomodulation: A Randomized Clinical Trial." Journal of Pharmacy and Bioallied Sciences 16, Suppl 2 (2024): S1792—S1794. http://dx.doi.org/10.4103/jpbs.jpbs_1143_23.

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ABSTRACT Background: Orthodontic treatment often spans several months or even years, which can be burdensome for patients. Biomodulation techniques have emerged as potential strategies to expedite orthodontic tooth movement. Materials and Methods: A randomized clinical trial was conducted with a sample of 60 orthodontic patients, aged 12–30 years, requiring fixed appliance therapy. Patients were randomly assigned to either the biomodulation group (n = 30) or the control group (n = 30). The biomodulation group received low-level laser therapy (LLLT) along with traditional orthodontic treatment,
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Dr., Mansi Mehta, Khyati Patel Dr., Ajay Kubavat Dr., and Alpesh Vaghela Dr. "Role of Genetics in Orthodontics – Simplified Concept." International Journal of Innovative Science and Research Technology 7, no. 11 (2022): 963–67. https://doi.org/10.5281/zenodo.7420594.

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In oral cavity, disturbances due to genetic alterations may range from lack of tooth development to morphological defects. Due to technical advances in genetic engineering and molecular biology, valuable information regarding dentofacial growth could be studied in detailed manner. This helps us to explain the aetiology and pathogenesis of many dentofacial disorders. The success in treatment lies first in determining the aetiology of tooth anomalies and finally differentiating the effect of genes and environment on the orofacial diseases of that particular individual. Types of Genetic Factors i
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Agrawal, Miral, Shefali Sharma, and Parmeshwari Rathod. "Periodontally Accelerated Osteogenic Orthodontics (PAOO) vs Osteoperforations (A Review on Periodontal Reactions to Orthodontic Tooth Movement)." Academic Journal of Research and Scientific Publishing 3, no. 32 (2021): 36–51. http://dx.doi.org/10.52132/ajrsp.e.2021.32.2.

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A high number of adult patients are undertaking orthodontic treatment now because of the newer methods, technology, and innovations available in the market. Orthodontic profession is continually looking for new ways to perform treatment effectively for such patients, as there are many differences in the biology, motivation, and treatment objectives between adults and children. Aligner therapy and mini-implants are some of the ways of managing orthodontic treatment for adult patients. Treatment time is a concern for adult patients and methods to accelerate the orthodontic tooth movement have be
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Krishnajith, J. K., K. K. Manjusha, A. Nishad, Abin Mohammed, M. A. Aparna, and Praveen Roy. "Effect of Micro Osteoperforation with Mini Implant on Rate of Tooth Movement During Maxillary Arch En-Masse Retraction in Class I Malocclusion Cases-A Split Mouth Study." Journal of Pharmacy and Bioallied Sciences 16, Suppl 5 (2024): S4608—S4612. https://doi.org/10.4103/jpbs.jpbs_962_24.

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ABSTRACT Aims: Extended orthodontic treatment leads to a number of negative outcomes, including a higher chance of dental cavities, gingival recession, open gingival embrasure gaps, and root resorption. It has been stated that micro osteoperforations (MOPs) use the biology of the body to speed up tooth movement. Our objective was to investigate how MOPs with micro implants affected the tooth movement rate. Methods: A parallel arm clinical trial at Noorul Islam College of Dental Sciences involved 36 maxillary quadrants from 18 patients aged 14–20 with class I malocclusion requiring maxillary fi
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Nixon, C., and G. King. "Macrophage chemotaxis in experimental tooth movement in the rat." Archives of Oral Biology 30, no. 10 (1985): 739–43. http://dx.doi.org/10.1016/0003-9969(85)90186-4.

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40

Zou, Min, Chenshuang Li, and Zhong Zheng. "Remote Corticotomy Accelerates Orthodontic Tooth Movement in a Rat Model." BioMed Research International 2019 (June 17, 2019): 1–9. http://dx.doi.org/10.1155/2019/4934128.

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Introduction. With an increasing demand for orthodontic treatment for adult patients, orthodontic professionals are constantly seeking novel strategies and technologies that can accelerate tooth movement in order to shorten the treatment period. For instance, in recent years, the influences of different surgical techniques on orthodontic tooth movement in the ipsilateral side of surgery were intensively investigated. Here, we attempt to examine if corticotomy could also affect the rate of tooth movement in the contralateral side of the surgery by using a rodent model. Materials and Methods. 72
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41

Yamaguchi, Masaru, and Shinichi Fukasawa. "Is Inflammation a Friend or Foe for Orthodontic Treatment?: Inflammation in Orthodontically Induced Inflammatory Root Resorption and Accelerating Tooth Movement." International Journal of Molecular Sciences 22, no. 5 (2021): 2388. http://dx.doi.org/10.3390/ijms22052388.

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The aim of this paper is to provide a review on the role of inflammation in orthodontically induced inflammatory root resorption (OIIRR) and accelerating orthodontic tooth movement (AOTM) in orthodontic treatment. Orthodontic tooth movement (OTM) is stimulated by remodeling of the periodontal ligament (PDL) and alveolar bone. These remodeling activities and tooth displacement are involved in the occurrence of an inflammatory process in the periodontium, in response to orthodontic forces. Inflammatory mediators such as prostaglandins (PGs), interleukins (Ils; IL-1, -6, -17), the tumor necrosis
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Liu, Yuanbo, Yilong Ai, Xuan Sun, et al. "Interleukin-20 Acts as a Promotor of Osteoclastogenesis and Orthodontic Tooth Movement." Stem Cells International 2021 (May 26, 2021): 1–20. http://dx.doi.org/10.1155/2021/5539962.

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Objectives. Bones constitute organs that are engaged in constant self-remodelling. Osteoblast and osteoclast homeostasis during remodelling contribute to overall skeletal status. Orthodontics is a clinical discipline that involves the investigation and implementation of moving teeth through the bone. The application of mechanical force to the teeth causes an imbalance between osteogenesis and osteogenesis in alveolar bone, leading to tooth movement. Osteoimmunology comprises the crosstalk between the immune and skeletal systems that regulate osteoclast–osteoblast homeostasis. Interleukin- (IL-
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Patil, AnandK, AdarshS Shetty, Swati Setty, and Srinath Thakur. "Understanding the advances in biology of orthodontic tooth movement for improved ortho-perio interdisciplinary approach." Journal of Indian Society of Periodontology 17, no. 3 (2013): 309. http://dx.doi.org/10.4103/0972-124x.115648.

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Domínguez Camacho, Angela, and Sergio Andres Velásquez Cujar. "Reevaluation of the Strain Pressure Theory: Toward a Better Understanding the Biology of Tooth Movement." International journal of odontostomatology 11, no. 2 (2017): 133–40. http://dx.doi.org/10.4067/s0718-381x2017000200003.

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LIU, ZI JUN, GREGORY J. KING, GAO MAN GU, JA YOUNG SHIN, and DENNIS R. STEWART. "Does Human Relaxin Accelerate Orthodontic Tooth Movement in Rats?" Annals of the New York Academy of Sciences 1041, no. 1 (2005): 388–94. http://dx.doi.org/10.1196/annals.1282.059.

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Zhou, Yuling, Xin He, and Dongliang Zhang. "Study of bone remodeling in corticotomy‐assisted orthodontic tooth movement in rats." Journal of Cellular Biochemistry 120, no. 9 (2019): 15952–62. http://dx.doi.org/10.1002/jcb.28872.

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Kinjo, Ria, Hideki Kitaura, Saika Ogawa та ін. "Micro-Osteoperforations Induce TNF-α Expression and Accelerate Orthodontic Tooth Movement via TNF-α-Responsive Stromal Cells". International Journal of Molecular Sciences 23, № 6 (2022): 2968. http://dx.doi.org/10.3390/ijms23062968.

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Micro-osteoperforations (MOPs) have been reported to accelerate orthodontic tooth movement (OTM), and tumor necrosis factor (TNF)-α has been reported to play a crucial role in OTM. In this report, the influence of MOPs during OTM was analyzed. We evaluated the expression of TNF-α with and without MOPs by RT-PCR analysis. A Ni-Ti closed coil spring was fixed between the maxillary left first molar and the incisors as an OTM mouse model to move the first molar in the mesial direction. MOPs were prepared on the lingual side and mesial side of the upper first molars. Furthermore, to investigate the
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Sinha, Abhishek, Tara V. Avirachan, Paul V. Thomas, Leelamma Kuruvilla, Parag S. Majithia, and Mithun Paul. "Accelarated Orthodontic Treatment Using Microosteoperforations: A Comparative Study." Journal of Pharmacy and Bioallied Sciences 16, Suppl 2 (2024): S1805—S1807. http://dx.doi.org/10.4103/jpbs.jpbs_1168_23.

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ABSTRACT Background: Accelerated orthodontic treatment has gained popularity in recent years as patients seek shorter treatment durations. Microosteoperforations (MOPs) have emerged as a minimally invasive technique to expedite tooth movement. This study aims to compare the effectiveness of MOPs in accelerating orthodontic treatment with conventional methods. Materials and Methods: A randomized controlled trial was conducted on 60 orthodontic patients requiring dental alignment. The participants were divided into two groups: Group A (MOPs) and Group B (conventional orthodontic treatment). In G
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Parashos, Peter. "The orthodontic-endodontic interface: trauma and pulpal considerations." British Dental Journal 237, no. 5 (2024): 389–97. http://dx.doi.org/10.1038/s41415-024-7786-9.

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AbstractThe interpretation of the clinical signs and symptoms arising from the interdisciplinary relationship between orthodontics and endodontics becomes more complicated when superimposed by dental trauma. A history of dental trauma before or during orthodontic tooth movement may have implications for pulpal health and clinical outcomes. An understanding of the biology is essential for appropriate treatment planning. This review and treatment recommendations will assist dental practitioners in managing orthodontic-endodontic interactions.
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Hadi, Lina, Albert Manggading Hutapea та Florenly Florenly. "Effects of Hydrogen-Rich Water on Interleukin-1β, Number of Osteoclasts and Osteoblasts in Streptozotocin-induced Diabetic Rats with Orthodontic Tooth Movement". Indonesian Biomedical Journal 15, № 6 (2023): 420–8. http://dx.doi.org/10.18585/inabj.v15i6.2677.

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BACKGROUND: Orthodontic tooth movement (OTM) may increase the risk of treatment-related complications for some diabetes mellitus (DM) patients. Hydrogen-rich water (HRW) has been demonstrated in many studies to reduce oxidative stress and cell damage. This study aimed to examine the levels of interleukin (IL)-1β, blood glucose level, body weight, tooth displacement, and population of osteoclasts and osteoblasts in diabetic rats with OTM.METHODS: Thirty rats (Rattus novergicus) were divided into 6 groups: OTM, HRW, DM, DM+OTM, DM+HRW, and DM+OTM+HRW. DM, DM+OTM, DM+HRW, and DM+OTM+HRW groups we
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