Relevant bibliographies by topics / TopA

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  2. Dissertations / Theses
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  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'TopA'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 February 2022

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Journal articles on the topic "TopA"

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Magri, Dirceu, and Joelma Santana Siqueira. "Francisco Topa - Entrevista." Jangada: crítica | literatura | artes, no. 12 (December 21, 2018): 178–84. http://dx.doi.org/10.35921/jangada.v1i12.213.

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Francisco Topa é Professor Associado do Departamento de Estudos Românicos da Faculdade de Letras da Universidade do Porto, lecionando nas áreas de Literatura e Cultura Brasileiras, Crítica Textual, Literaturas Africanas de Língua Portuguesa e Literaturas Orais e Marginais. Doutorou-se em Literatura, em 2000, na mesma Faculdade, com uma tese sobre o poeta barroco Gregório de Matos. Obteve em 2016, também na FLUP, o título de Agregado em Estudos Literários, Culturais e Interartísticos, especialidade de Literatura e Cultura. Sua investigação tem estado dirigida para a literatura portuguesa e brasileira dos séculos XVII e XVIII, para as literaturas africanas de língua portuguesa e para algumas áreas da literatura oral e marginal. Tem participado em congressos da especialidade, em Portugal e no estrangeiro, e é autor de vinte livros e de cerca de uma centena de artigos e outras publicações nos domínios mencionados.
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Williams, Neal K., and Judith P. Klinman. "Whence topa? Models for the biogenesis of topa quinone in copper amine oxidases." Journal of Molecular Catalysis B: Enzymatic 8, no. 1-3 (2000): 95–101. http://dx.doi.org/10.1016/s1381-1177(99)00071-5.

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Kano, Kenji, Toshio Mori, Bunji Ono, Masashi Goto, and Tokuji Ikeda. "Characterization of topa quinone cofactor." Biochimica et Biophysica Acta (BBA) - General Subjects 1157, no. 2 (1993): 324–31. http://dx.doi.org/10.1016/0304-4165(93)90117-q.

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Yan, Rong, Shikun Hu, Ning Ma, et al. "Regulatory Effect of DNA Topoisomerase I on T3SS Activity, Antibiotic Susceptibility and Quorum- Sensing-Independent Pyocyanin Synthesis in Pseudomonas aeruginosa." International Journal of Molecular Sciences 20, no. 5 (2019): 1116. http://dx.doi.org/10.3390/ijms20051116.

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Topoisomerases are required for alleviating supercoiling of DNA during transcription and replication. Recent evidence suggests that supercoiling of bacterial DNA can affect bacterial pathogenicity. To understand the potential regulatory role of a topoisomerase I (TopA) in Pseudomonas aeruginosa, we investigated a previously isolated topA mutation using genetic approaches. We here report the effects of the altered topoisomerase in P. aeruginosa on type III secretion system, antibiotic susceptibility, biofilm initiation, and pyocyanin production. We found that topA was essential in P. aeruginosa, but a transposon mutant lacking the 13 amino acid residues at the C-terminal of the TopA and a mutant, named topA-RM, in which topA was split into three fragments were viable. The reduced T3SS expression in topA-RM seemed to be directly related to TopA functionality, but not to DNA supercoiling. The drastically increased pyocyanin production in the mutant was a result of up-regulation of the pyocyanin related genes, and the regulation was mediated through the transcriptional regulator PrtN, which is known to regulate bacteriocin. The well-established regulatory pathway, quorum sensing, was unexpectedly not involved in the increased pyocyanin synthesis. Our results demonstrated the unique roles of TopA in T3SS activity, antibiotic susceptibility, initial biofilm formation, and secondary metabolite production, and revealed previously unknown regulatory pathways.
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Karović, Dragan. "Neke mogućnosti povećanja efikasnosti projektila avionskog topa." Vojnotehnicki glasnik 40, no. 5 (1992): 12–14. http://dx.doi.org/10.5937/vojtehg9201012k.

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Mure, Minae, and Katsuyuki Tanizawa. "Chemical and Biochemical Characteristics of Topa Quinone." Bioscience, Biotechnology, and Biochemistry 61, no. 3 (1997): 410–17. http://dx.doi.org/10.1271/bbb.61.410.

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Stewart, Natalee, Jingyang Feng, Xiaoping Liu, et al. "Loss of topoisomerase I function affects the RpoS-dependent and GAD systems of acid resistance in Escherichia coli." Microbiology 151, no. 8 (2005): 2783–91. http://dx.doi.org/10.1099/mic.0.28022-0.

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Acid resistance (AR) in Escherichia coli is important for its survival in the human gastrointestinal tract and involves three systems. The first AR system is dependent on the sigma factor RpoS. The second system (the GAD system) requires the glutamate decarboxylase isoforms encoded by the gadA and gadB genes. The third system (the ARG system) requires the arginine decarboxylase encoded by adiA. Loss of topoisomerase I function from topA deletion or Tn10 insertion mutations lowered the resistance to killing by pH 2 or 2·5 treatment by 10-fold to >100-fold. The RpoS and GAD systems were both affected by the topA mutation, but the ARG system of AR was not affected. Northern blot analysis showed that induction of gadA and gadB transcription in stationary phase and at pH 5·5 was decreased in the topA mutant. Western blot analysis showed that the topA mutation did not affect accumulation of RpoS, GadX or GadW proteins. Topoisomerase I might have a direct influence on the transcription of AR genes. This influence does not involve R-loop formation as the overexpression of RNase H did not alleviate the decrease of AR caused by the topA mutation. The effect of the topA mutation could be suppressed by an hns mutation, so topoisomerase I might be required to counteract the effect of H-NS protein on gene expression, in addition to its influence on RpoS-dependent transcription.
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Wilfong, Lalan S., John Russell Hoverman, Nate Gosse, Marcus A. Neubauer, and Vanessa Torres. "Changing physician compensation and implementing new technology to enhance pathways compliance." Journal of Clinical Oncology 34, no. 7_suppl (2016): 187. http://dx.doi.org/10.1200/jco.2016.34.7_suppl.187.

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187 Background: Pathways have shown to decrease cost of care while maintaining efficacy of treatment. In 2005, The US Oncology Network, which includes Texas Oncology, P.A. (TOPA) developed physician-led clinical pathways based on national guidelines, cost and efficacy. This abstract reviews the impact of changes TOPA initiated to improve pathway compliance Methods: Since 2011, TOPA has assessed pathways compliance using the iKnowMed (iKM) electronic medical record. Individual compliance was reported to each physician, but no incentives were tied to this. In 2015, the TOPA annual productivity bonus structure (2% of compensation) was changed to introduce pathways compliance and exception documentation thresholds, with penalties for sub-threshold performance. Additionally, TOPA sought to improve on iKM-based data collection and assessment. Previously, there were data challenges with pathways assessed retrospectively, offering limited visibility at the time of decision-making. In September 2015, new technology (Clear Value Plus – CVP) was embedded within iKM, which allowed prospective pathways assessment and provided real-time compliance reporting. Results: Introduction of individual incentives and improved decision support increased pathways compliance. For the initial yearly bonus measurement period, TOPA pathways compliance was 78%. After implementation of the new bonus structure, compliance increased significantly to 83% (p<0.0001). Implementation of CVP further improved pathway compliance for comparable reporting periods from 78% in September 2014 to 90% in September of 2015 (p<0.0001) Conclusions: We have shown that even a small change in compensation significantly influences physician pathways compliance. Additionally, technology to assist physicians with documentation and real-time assessment also significantly improves pathway compliance. [Table: see text] [Table: see text]
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Klinman, Judith P. "The multi-functional topa-quinone copper amine oxidases." Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1647, no. 1-2 (2003): 131–37. http://dx.doi.org/10.1016/s1570-9639(03)00077-3.

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Hammond, G. G., P. J. Cassidy, and K. M. Overbye. "Novobiocin-dependent topA deletion mutants of Escherichia coli." Journal of Bacteriology 173, no. 17 (1991): 5564–67. http://dx.doi.org/10.1128/jb.173.17.5564-5567.1991.

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Dissertations / Theses on the topic "TopA"

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MacCormack, Sabine. "¿Inca o español? Las identidades de Paullu Topa Inca." Pontificia Universidad Católica del Perú, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/113531.

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Inca or Spanish? The Identities of Paullu Topa IncaPaullu Topa Inca tends to be described, in modern historiography, as a traitor to his own people. This judgement misrepresents the circumstances of his life as perceived during the sixteenth century. During his own life time, he was indeed respected by many Spaniards, but Incas and andean people also regarded him as a man of very great authority and worth. After his death, the complex events of the invasion and conquest in which Paullu Topa Inca participated were streamlined into a smooth narrative that fitted in with the perspective of the winning side in the civil wars of the conquest period, and that became canonical once the viceregal state was established. The old men who at century’s end remembered Paullu Topa Inca did so as part of their own memories of their childhood and youth.<br>En la historiografía moderna, Paullu Topa Inca aparece como traidor de su gente. Este juicio da una imagen falsa de las circunstancias de su vida como la representaron sus contemporáneos. Durante su existencia, muchos españoles lo respetaron, y los incas y la gente andina lo miraron como hombre de gran autoridad y valía. Después de muerto, los sucesos complejos de invasión y conquista en los que Paullu Topa Inca participó fueron transformados en una narrativa llana y sencilla, según las ideas del partido victorioso en las guerras civiles. Esta narrativa se hizo canónica, una vez que se estableció el Estado virreinal. Los viejos que recordaban a Paullu Topa Inca lo hicieron en el contexto de sus propias memorias de niñez y juventud.
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Souza, Leila Damiana Almeida dos S. "Missão do SAHY: Hãm ha Topa, yãymaih xix ayuhuk (Terra de Deus, índios e não-índios)." Instituto de Humanidades, Artes e Ciências, 2013. http://repositorio.ufba.br/ri/handle/ri/14591.

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Submitted by Leila Souza (leila.damiana@ufrb.edu.br) on 2014-02-04T14:01:23Z No. of bitstreams: 1 DISSERTAÇÃO. Leila Damiana A. Santos Souza.MISSÃO DO SAHY. Hãm ha Topa, yãymaih xix ayuhuk (2).doc: 11707904 bytes, checksum: a6e1ed07346c382310ff17df6b588570 (MD5)<br>Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-02-13T17:24:04Z (GMT) No. of bitstreams: 1 DISSERTAÇÃO. Leila Damiana A. Santos Souza.MISSÃO DO SAHY. Hãm ha Topa, yãymaih xix ayuhuk (2).doc: 11707904 bytes, checksum: a6e1ed07346c382310ff17df6b588570 (MD5)<br>Made available in DSpace on 2014-02-13T17:24:04Z (GMT). No. of bitstreams: 1 DISSERTAÇÃO. Leila Damiana A. Santos Souza.MISSÃO DO SAHY. Hãm ha Topa, yãymaih xix ayuhuk (2).doc: 11707904 bytes, checksum: a6e1ed07346c382310ff17df6b588570 (MD5)<br>RESUMO Este trabalho versa sobre os processos identitários de um grupo de descendentes indígenas da comunidade Missão do Sahy, distrito do Município de Senhor do Bonfim - BA. Foi realizada uma retomada histórica onde se buscaram aspectos que indicassem uma atribuição de características culturais aos descendentes de índios. O estudo da historiografia, juntamente com as narrativas orais dos moradores, voltou-se para os primeiros contatos dos europeus com os povos tradicionais brasileiros, passando pela situação dos índios no nordeste e na Bahia. Utilizamos formulações epistemológicas acerca da “misturação dos índios”, do hibridismo cultural e da diáspora. O enquadramento teórico ladeado pelo estudo de caso objetivou analisar a partir das narrativas como os processos de atribuição da identidade conduziram o (não) pertencimento étnico dos descendentes indígenas da Missão do Sahy. Foram utilizados, entre outros, autores como: Da Paz, Machado, Pacheco de Oliveira, Paula Caleffi, Canclini, Homi Bhabha e Stuart Hall. As análises qualitativas do estudo de caso foram possibilitadas pela relação dialógica entre pesquisadora e objeto de estudo a partir da valorização das respostas obtidas, assim, foi possível construir a imbricação da historiografia, dos pressupostos teóricos e das narrativas orais desde o primeiro capítulo do trabalho. Os resultados revelaram que aos indígenas diversas identidades foram atribuídas em diferentes épocas e contextos, essa atribuição gerou uma desconstrução das identidades que se deu por meio de um processo de “misturação” e pelo hibridismo cultural. Por outro lado, a luta e a emergência de grupos indígenas apontavam para a existência de um processo de constituição de identidades individual e coletiva, conquanto as investigações apontaram que também na Missão do Sahy esse processo ocorreu (ocorre). Foi por meio das formulações acerca da diáspora que se chegou à compreensão de que as novas identidades no plano cultural vêm se constituindo numa dinâmica de produção e autoprodução, onde os descendentes assumem não só o seu pertencimento, mas também buscam meios para se afirmarem como comunidade descendente dos índios Cariri e Paiaiás. Palavras-chave: Descendentes Indígenas. Diáspora. Hibridismo. Identidades.<br>RÉSUMÉ Ce travail s´agit de l´investigation sur les processus identitaires d´un groupe de descendants d´indigènes de la communauté appelée Missão do Sahy, dans un petit village situé dans la ville de Senhor do Bonfim, à l´état de Bahia, Brésil. Nous avons fait une description de les plus importantes moments de cette histoire, oú on a remarqué des aspects qui dénote l´attribution des caractéristiques culturelles aux descendants d´indigènes. L´étude de l´historiographie, avec les narratives orales des habitants, a mise-en-relief les premiers contacts des européens avec les peuples traditionnels brésiliens, notamment sur la situation des indigénes de la región Nordeste et de l´etat de Bahia. Nous avons utilisé de la pensée épistémologique de la “mixage des indigènes”, de l´hybridité culturelle et de la diaspora. La base theorique accompagné par l´étude de cas, a eut le but d´analyser, apartir des narratives, comment les processus d´attribution de l´identité ont conduit le (non) appartenance éthnique des descendants indigènes de la Missão do Sahy. Nous utilisons les contributions theoriques de Da Paz, Machado, Pacheco de Oliveira, Paula Caleffi, Canclini, Homi Bhabha e Stuart Hall, parmi d´autres. La realisation d´analyses qualitatives de l´étude de cas ont été possible à cause de la relation dialogique entre la chercheuse et l´objet d´étude apartir d´une valorisation de tous les réponses reçues. De cette façon, nous avons fait l´imbrication de l´historiographie, de la base théorique et des narratives orales depuis le premier partie du travail. Les resultats ont revelé que plusieurs identités étaient attribuée aux indigènes pendant des différentes époques et contextes. Cette attribution a creé une (dé)constrution des identités à travers d´un processus de “mixage” et par l´hybridisme culturelle. Par contre, la lutte et l´emergence des groupes indigenes ont souligné l´existence d´un processus de constitution d´identités au niveau individuel et collectif; cependant, l´investigation a montré que ce processus est arrivé (et arrive) aussi dans la Missão do Sahy. Il était à travers des réfléchissements sur la diaspora que ont a compris que les nouvelles identités au plan culturelle sont construit dans une dynamique de production e auto-production, oú les descendants affirment pas seulement leur appartennance, mais ils cherchent aussi des moyens pour s´affirmer comme une communauté descendent des indigènes Cariri e Paiaiás. Mots-Clés: Descendants d´indigènes. Diaspora. Hybridisme. Identités.
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Barros, Ludimila de Oliveira. "Nas p?ginas do livro-mundo, travessias do alfabetizar: saberes e pr?ticas de professores alfabetizadores do TOPA/UEFS." Universidade Estadual de Feira de Santana, 2016. http://localhost:8080/tede/handle/tede/443.

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Submitted by Ricardo Cedraz Duque Moliterno (ricardo.moliterno@uefs.br) on 2017-02-14T22:48:29Z No. of bitstreams: 1 LUDIMILA BARROS. Disserta??o de Mestrado. PPGE2016.pdf: 1224261 bytes, checksum: 73682ebd9cde5b626cf8443fc6814194 (MD5)<br>Made available in DSpace on 2017-02-14T22:48:29Z (GMT). No. of bitstreams: 1 LUDIMILA BARROS. Disserta??o de Mestrado. PPGE2016.pdf: 1224261 bytes, checksum: 73682ebd9cde5b626cf8443fc6814194 (MD5) Previous issue date: 2016-09-30<br>Funda??o de Amparo ? Pesquisa do Estado da Bahia - FAPEB<br>This paper seeks to understand the pedagogical practices of literacy teachers from the Todos pela Alfabetiza??o Program implemented by Universidade Estadual of Feira de Santana (TOPA / UEFS) and the knowledge mobilized by them in their literacy "crossings". The investigation lies in the field of qualitative research, based on the emerging paradigm of science (SANTOS, 1995), in connection with the approach of the History of Everyday Life (CERTEAU, 1998). The locus of this study was the city of Feira de Santana, where literacy teachers from TOPA have served as collaborators. There were a total of six respondents in this research: five literacy teachers from TOPA and a general coordinator of the program during the years of 2007-2011. In addition to the narrative interviews, UEFS?s Pr? Reitoria de Extens?o (PROEX/UEFS) provided documents used for training teachers from TOPA that were employed in the production of data analysis contained in this work. Academic reflections were woven from the theoretical and methodological assumptions of the Youth and Adult Education (Freire, 2011), in connection with the field of Teacher Training and Teacher Knowledges (Tardif, 2012; CHARLOT, 2000). Of the many lessons learned, it is clear that learning and teaching to read necessarily entails the understanding of the world around us and the seizure of the realities that reach us. This interpretation has helped us to think about the everyday life and the experiences in the routine processes of life-training, as producers of experiential knowledge that are so important to the teaching practice. Thus, it can be concluded that: 1) the pedagogical practice of literacy teachers from TOPA / UEFS are necessarily involved with their own cultural repertoires and with their learners?; 2) the literacy teachers from TOPA / UEFS in their everyday classrooms, give other meanings to the teaching training they receive in order to obtain success in literacy processes; and 3) the knowledge mobilized by literacy teachers in their literacy crossings intermingle with their experiences of "existing and being" on / with the world.<br>Este trabalho busca compreender as pr?ticas pedag?gicas dos professores alfabetizadores do Programa Todos pela Alfabetiza??o implementado pela Universidade Estadual de Feira de Santana (TOPA/UEFS), e os saberes mobilizados por eles em suas ?travessias? do alfabetizar. A investiga??o situa-se no campo da pesquisa qualitativa, amparada no paradigma emergente de ci?ncia (SANTOS, 1995), e em di?logo com a abordagem da Hist?ria do Cotidiano (CERTEAU, 1998). O l?cus foi a cidade de Feira de Santana, visto que os colaboradores desse trabalho atuaram como alfabetizadores do TOPA nesse munic?pio, e os sujeitos informantes dessa pesquisa foram um total de seis: cinco alfabetizadores do TOPA e uma coordenadora geral do programa entre os anos de 2007 a 2011. Al?m das entrevistas narrativas, utilizamos documentos da forma??o docente do TOPA, disponibilizados pela Pr? Reitoria de Extens?o da UEFS (PROEX/UEFS), na produ??o das an?lises de dados que constam nesse trabalho. As reflex?es acad?micas foram tecidas a partir dos pressupostos te?rico-metodol?gicos da Educa??o de Jovens e Adultos (FREIRE, 2011), em di?logo com o campo da Forma??o de Professores e Saberes Docentes (TARDIF, 2012; CHARLOT, 2000). Das muitas li??es apreendidas, ? poss?vel afirmar que aprender e ensinar a leitura implica, necessariamente, na compreens?o do mundo que nos cerca e na apreens?o das realidades que nos alcan?am. Essa interpreta??o nos ajudou a pensar o cotidiano e as experi?ncias vivenciadas nos processos rotineiros de vida-forma??o, como produtores de saberes experienciais t?o relevantes para a pr?tica docente. Assim, conclu?mos que: 1) a pr?tica pedag?gica dos alfabetizadores do TOPA/UEFS, se implicam, necessariamente, com os seus repert?rios culturais e de seus alfabetizandos; 2) os alfabetizadores do TOPA/UEFS, no cotidiano de suas salas de aula, d?o outros significados ? forma??o docente que recebem, no sentido de obterem ?xito nos processos de alfabetiza??o; e 3) os saberes mobilizados pelos alfabetizadores, em suas travessias do alfabetizar, se (con)fudem com suas experi?ncias de ?ser e estar? no/com o mundo.
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Amaral, Alencar Miranda. "Topa e a tentativa missionária de inserir o Deus cristão ao contexto Maxakali: análise do contato inter-religioso entre missionários cristãos e índios." Universidade Federal de Juiz de Fora (UFJF), 2007. https://repositorio.ufjf.br/jspui/handle/ufjf/3197.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-02-03T12:05:23Z No. of bitstreams: 1 alencarmirandaamaral.pdf: 1670327 bytes, checksum: 2d9c3f9a9d891835776120bfdbe35f33 (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-02-03T12:07:46Z (GMT) No. of bitstreams: 1 alencarmirandaamaral.pdf: 1670327 bytes, checksum: 2d9c3f9a9d891835776120bfdbe35f33 (MD5)<br>Made available in DSpace on 2017-02-03T12:07:46Z (GMT). No. of bitstreams: 1 alencarmirandaamaral.pdf: 1670327 bytes, checksum: 2d9c3f9a9d891835776120bfdbe35f33 (MD5) Previous issue date: 2007-08-31<br>CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Nesta dissertação de mestrado analiso o contato inter-religioso promovido pela atuação de missões evangélicas (SIL e MNTB) junto à comunidade indígena Maxakali, localizada no nordeste do Estado de Minas Gerais. Além de acompanhar o desenvolvimento das atividades proselitistas destas instituições entre os índios Maxakali, objetivamos compreender como ao longo do contato inter-religioso ocorre o processo de identificação do Deus cristão com o personagem indígena Topa. Na bibliografia sobre os índios Maxakali, Topa aparece como o personagem central do “mito de criação” do grupo, e apesar de alguns autores reconhecerem que seu nome também era associado ao Deus cristão, não existem análises sobre este processo. Assim, nosso desafio será compreender como Topa foi, e vêm sendo, apropriado de diferentes maneiras ao longo do contato entre os Maxakali e os missionários evangélicos; e também analisar o processo que possibilitou que este personagem gradativamente fosse identificado com o Deus cristão. O escopo desta pesquisa é, portanto, perceber o esforço missionário de inserir o Deus cristão ao contexto Maxakali através do personagem Topa. A partir da análise de mitos Maxakali e hinos evangélicos traduzidos para o idioma do grupo buscaremos compreender este processo de associação, e também a (in)adequação dos ensinamentos missionários aos padrões sócioculturais e religiosos dos índios Maxakali.<br>In this master’s dissertation, I analyze the pro inter-religious contact heard by acts of evangelic missions (SIL and MNTB) on the Maxakali Indian at the northeast of Minas Gerais. Besides of studying the proselytizes activities of this institutions among the Maxakali Indians, we have the goal to understand how the Indians started to associate Topa (the Indian character) as the Christian God during this inter-religious contact. In the Maxakali biography, Topa come as the central character of the “creation myth” of the group an despite of the fact that some authors recognize Topa as the Christian God in their works, that are no analysis about it. So the challenge here is to understand how Topa was used in so many ways during the contact between the Maxakali and the evangelic missionaries; and analyze the process the made possible this character to be gradually associated with the Christian God. Hence, the purpose of this research is to realize the missionary effort to introduce the Christian God in the Maxakali context through Topa. From the analysis of the Maxakali myths an evangelic religions songs translated to their idiom, we will try understand the association process, and also how (in)adequate were the Christian teaching to the Maxakali religious and social-cultural standards.
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Zhi, Xiaoduo. "Transcription-Coupled DNA Supercoiling in Escherichia Coli: Mechanisms and Biological Functions." FIU Digital Commons, 2012. http://digitalcommons.fiu.edu/etd/865.

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Transcription by RNA polymerase can induce the formation of hypernegatively supercoiled DNA both in vivo and in vitro. This phenomenon has been explained by a “twin-supercoiled-domain” model of transcription where a positively supercoiled domain is generated ahead of the RNA polymerase and a negatively supercoiled domain behind it. In E. coli cells, transcription-induced topological change of chromosomal DNA is expected to actively remodel chromosomal structure and greatly influence DNA transactions such as transcription, DNA replication, and recombination. In this study, an IPTG-inducible, two-plasmid system was established to study transcription-coupled DNA supercoiling (TCDS) in E. coli topA strains. By performing topology assays, biological studies, and RT-PCR experiments, TCDS in E. coli topA strains was found to be dependent on promoter strength. Expression of a membrane-insertion protein was not needed for strong promoters, although co-transcriptional synthesis of a polypeptide may be required. More importantly, it was demonstrated that the expression of a membrane-insertion tet gene was not sufficient for the production of hypernegatively supercoiled DNA. These phenomenon can be explained by the “twin-supercoiled-domain” model of transcription where the friction force applied to E. coli RNA polymerase plays a critical role in the generation of hypernegatively supercoiled DNA. Additionally, in order to explore whether TCDS is able to greatly influence a coupled DNA transaction, such as activating a divergently-coupled promoter, an in vivo system was set up to study TCDS and its effects on the supercoiling-sensitive leu-500 promoter. The leu-500 mutation is a single A-to-G point mutation in the -10 region of the promoter controlling the leu operon, and the AT to GC mutation is expected to increase the energy barrier for the formation of a functional transcription open complex. Using luciferase assays and RT-PCR experiments, it was demonstrated that transient TCDS, “confined” within promoter regions, is responsible for activation of the coupled transcription initiation of the leu-500 promoter. Taken together, these results demonstrate that transcription is a major chromosomal remodeling force in E. coli cells.
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6

Dianderas, Gutierrez Enrique, Orchard Sergio Andrés López, Saldaña Alexis Samohod, and De la Vega Karen Yarasca. "Planeamiento estratégico de la empresa Topy Top." Master's thesis, Pontificia Universidad Católica del Perú, 2018. http://tesis.pucp.edu.pe/repositorio/handle/123456789/12677.

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En el Planeamiento Estratégico para la empresa Topy Top se ha planteado como visión que para el 2023 sea reconocida como la empresa peruana líder en la industria de confecciones de prendas de vestir y una referencia dentro de América Latina incrementando su presencia en América del Norte y Europa. La posición competitiva de la que goza la compañía y una perspectiva positiva en la demanda global de prendas de vestir ofrecen el panorama ideal para la implementación de este plan estratégico. Se han formulado seis objetivos de largo plazo todos enfocados al año 2023, los cuales se listan a continuación: (a) localizarse en el primer lugar en la industria de confecciones peruanas, (b) aumentar las ventas en 15% anual, (c) contar con una marca premium orientada al mercado europeo, (d) incrementar las exportaciones en 10% anual, (e) aumentar la producción a 5’000,000 de prendas mensuales, e (f) incrementar el retorno sobre la inversión de cinco a ocho por ciento. Estos objetivos de largo plazo, han sido divididos en 20 objetivos de corto plazo que conduzcan de forma progresiva hacia la consecuión de la misión. Estos objetivos serán permanente evaluados y monitoreados a través del Balance Scorecard mediante sus cuatros perspectivas: aprendizaje interno, proceso interno, clientes y financiero. Durante el análisis de la industria y de la compañía, se definieron 19 estrategias de las cuales 15 fueron retenidas en primer orden y las restantes quedaron como estrategias de contingencia. Topy Top identificará a sus mejores empleados para constituir un equipo multidisciplinario que lidere el cambio y conduzca a la compañía hacia el futuro deseado.<br>In the Strategic Planning for Topy Top has been proposed as a vision that by 2023 it will be recognized as the leading Peruvian company in the apparel industry and a reference within Latin America, increasing its presence in North America and Europe. The competitive position of the company and a positive outlook on the global demand for garments offers the ideal scenario for the implementation of this strategic plan. Six long-term objectives have been formulated, all focused on the year 2023, which are listed below: (a) lead the Peruvian apparel industry, (b) increasing sales by 15% per year, (c) counting with a premium brand oriented to the European market, (d) increasing exports by 10% per year, (e) increasing production to 5'000,000 pieces per month, and (f) increasing the return on investment from 5% to 8%. These long-term objectives have been divided into 20 short-term objectives that progressively lead to the achievement of the mission. These objectives are permanently evaluated and monitored through the Balance Scorecard for its four perspectives: internal learning, internal process, clients and financial. During the analysis of the industry and the company, 19 strategies were defined then 15 strategies have been retained and the remaining ones have been left as contingency strategies. Topy Top identified its best employees to form a multidisciplinary team that leads the company towards the desired future.<br>Tesis
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7

Theobald, Martin. "TopX efficient and versatile top-k query processing for text, structured, and semistructured data." Saarbrücken VDM Verlag Dr. Müller, 2006. http://d-nb.info/99139089X/04.

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Sanguineti, Raymond Wilfredo, Landaburu María Katia García, and Ponce Milagros Vivas. "Effects of multinational companies’ Corporate Social Responbility (CSE) commitments of the Peruvian labor market: the experience of Topy Top." Economía, 2015. http://repositorio.pucp.edu.pe/index/handle/123456789/118322.

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This paper studies the impact that the social responsibility commitments of multinational companies are can have in the settlement of labor disputes that arise in its supply chain through a landmark case that occurred in Peru. There, the en masse dismissal of union members and their representatives by the textiles company Topy Top was resolved through the intervention of two international brands that were clients of that company. This intervention not only enabled the reinstatement of the workers, but also generated a series of instruments designed to develop a mature system of industrial relations. Through an analysis of the agreements and instruments adopted and the way the relationship between the company and the union developed thereafter, we evaluate the role that multinational companies can assume to ensure the compliance of fundamental labor rights.<br>El presente trabajo estudia la incidencia que son capaces de tener los compromisos de responsabilidad social de las empresas multinacionales en la solución de conflictos laborales suscitados en sus cadenas de producción, a través de un caso emblemático que se produjo en el Perú, como consecuencia del cese masivo de representantes y afiliados sindicales por parte de la empresa Topy Top, que se solucionó a través de la intervención de dos marcas internacionales que eran clientes de dicha empresa. Esa intervención no solamente permitió la reposición de los trabajadores, sino que generó una serie de instrumentos que tenían por objeto desarrollar un sistema de relaciones industriales maduro. A través del análisis de los acuerdos e instrumentos adoptados y la forma cómo se desarrollaron las relaciones entre la empresa y el sindicato posteriormente, se evalúa el rol de garantía del cumplimiento de derechos laborales fundamentales que pueden asumir las empresas multinacionales.
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Cedeño, Rojas Maribel. "Arbeitsmittel und Arbeitsabläufe beim Übersetzen audiovisueller Medien Synchronisation und Untertitelung in Venezuela und in Deutschland." Trier Wiss. Verl. Trier, 2006. http://www.wvttrier.de/top/uebersetzwiss_r_programm.htm.

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Moenikes, Ansgar. "Tora ohne Mose : zur Vorgeschichte der Mose-Tora /." Berlin : Philo, 2004. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=013004084&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Books on the topic "TopA"

1

Devala, Candraprakāsa. Topa nāmā. Rājasthānī Granthāgāra, 1997.

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Newcomen Society of the United States., ed. Topa Equities, Ltd. Newcomen Society of the United States, 1996.

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E, Anderson John. Topa Equites, Ltd. Newcomen Society of the United States, 1996.

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Dhakal, Shiva. Topa carāko gunḍa: Bāla kathā. Ḍāyarī Prakāśana, 1988.

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Od trešnjevog topa do savremene artiljerije, 1804-1878. Vizartis, 2003.

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Topa, Manasārāmajī Śāstrī Vaidika. Paurāṇika popa para Vaidika Topa, arthāt Sanātanadharma kī mauta. Vijayakumāra Govindarāma Hāsn̄anda, 2003.

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Topa, Manasārāmajī Śāstrī Vaidika. Paurāṇika popa para Vaidika Topa, arthāt Sanātanadharma kī mauta. Bhagavatī Prakāśana, 1992.

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Hugo, James R. The Cabeza de Vaca family and its relationship to the Topa Inca Yupanqui dynasty of Peru. J.R. Hugo, 1985.

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Hilman. Topi-topi centil. 6th ed. Gramedia, 1989.

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Jornada, de Estudos Italianos em Honra de Giuseppe Mae (2008 Porto Portugal). Nel mezzo del cammin: Actas da Jornada de Estudos Italianos em Honra de Giuseppe Mae, (Porto, 24-25 de novembro de 2008) ; organização de Francisco Topa e Rita Marnoto. Sombra pela Cintura, 2009.

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Book chapters on the topic "TopA"

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Dooley, David M., Doreen E. Brown, Michele A. McGuirl, and L. J. Sears. "Mechanistic Studies of Copper/Topa Amine Oxidases." In Biochemistry of Vitamin B6 and PQQ. Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7393-2_41.

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Tanizawa, Katsuyuki, Ryuichi Matsuzaki, and Toshio Fukui. "Copper ion-dependent biogenesis of topa quinone cofactor covalently bound to bacterial monoamine oxidase." In Biochemistry of Vitamin B6 and PQQ. Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7393-2_43.

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Tanizawa, Katsuyuki, Hideyuki Matsunami, and Hiroshi Yamaguchi. "Mechanism of Topa Quinone Biogenesis in Copper Amine Oxidase Studied by Site-Directed Mutagenesis and X-Ray Crystallography." In Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins. Birkhäuser Basel, 2000. http://dx.doi.org/10.1007/978-3-0348-8397-9_11.

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Mehlhorn, Heinz. "TOVA." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_5012.

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Mehlhorn, Heinz. "TOVA." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_5012-1.

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Falke, D. "Toga-Viren." In Springer-Lehrbuch. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-662-08626-1_91.

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Jodorowsky, Alejandro. "El Topo." In 100 Cult Films. British Film Institute, 2011. http://dx.doi.org/10.1007/978-1-84457-571-8_92.

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Kochman, Stanley O. "Toda brackets." In Lecture Notes in Mathematics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/bfb0083797.

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Newey, Katherine, and Jeffrey Richards. "Toga Plays." In John Ruskin and the Victorian Theatre. Palgrave Macmillan UK, 2010. http://dx.doi.org/10.1057/9780230276512_4.

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Balliet, Kristy, and Brennan Buck. "Topo — Panelization." In Visual Catalog: Greg Lynn’s Studio. Springer Vienna, 2010. http://dx.doi.org/10.1007/978-3-211-99193-0_4.

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Conference papers on the topic "TopA"

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Victor, Allen, Thomas Zurbuchen, and Alec Gallimore. "Development of the Top Hat Electric Propulsion Plume Analyzer (TOPAZ)." In 40th AIAA/ASME/SAE/ASEE Joint Propulsion Conference and Exhibit. American Institute of Aeronautics and Astronautics, 2004. http://dx.doi.org/10.2514/6.2004-4099.

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Sugawara-Tanabe, Kazuko, and Kosai Tanabe. "Tops-on-top model for triaxial strongly deformed bands in even-A nuclei." In Proceedings of the French–Japanese Symposium. WORLD SCIENTIFIC, 2012. http://dx.doi.org/10.1142/9789814417952_0014.

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Ghezzi, Giacomo, Michael Wursch, Emanuel Giger, and Harald C. Gall. "An architectural blueprint for a pluggable version control system for software (evolution) analysis." In 2012 2nd Workshop on Developing Tools as Plug-ins (TOPI). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229803.

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Tajalli, H., and N. Medvidovic. "A reference architecture for integrated development and run-time environments." In 2012 2nd International Workshop on Developing Tools as Plug-ins (TOPI 2012). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229804.

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Schiller, Todd W., and Brandon Lucia. "Playing cupid: The IDE as a matchmaker for plug-ins." In 2012 2nd Workshop on Developing Tools as Plug-ins (TOPI). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229805.

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Karus, Siim. "XML development with plug-ins as a service." In 2012 2nd Workshop on Developing Tools as Plug-ins (TOPI). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229806.

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Kuhn, Adrian. "IDEs need become Open Data platforms (As need languages and VMs)." In 2012 2nd Workshop on Developing Tools as Plug-ins (TOPI). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229807.

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Chicote, Marcos, and Juan Pablo Galeotti. "TacoPlug: An Eclipse plug-in for TACO." In 2012 2nd Workshop on Developing Tools as Plug-ins (TOPI). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229808.

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Fahndrich, Manuel, Michael Barnett, Daan Leijen, and Francesco Logozzo. "Integrating a set of contract checking tools into Visual Studio." In 2012 2nd Workshop on Developing Tools as Plug-ins (TOPI). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229809.

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Catano, Nestor, K. Rustan M. Leino, and Victor Rivera. "The EventB2Dafny Rodin plug-in." In 2012 2nd Workshop on Developing Tools as Plug-ins (TOPI). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229810.

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Reports on the topic "TopA"

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Cochoy, Robert. Technical Operations Support (TOPS). Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada387660.

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Williamson, John. Technical Operations Support (TOPS). Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada387783.

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Prévost, C. Cartes topo sur mesures. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2001. http://dx.doi.org/10.4095/219852.

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Quigg, Chris. Top-ophilia. Office of Scientific and Technical Information (OSTI), 2008. http://dx.doi.org/10.2172/924922.

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Tartarelli, G. F. CDF top physics. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/244674.

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Bell, J. S. Structure, IV, Labrador sea, Top Bjarni and top Markland formations. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1989. http://dx.doi.org/10.4095/127185.

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Benitez, Jorge Armando. Uncovering the single top: observation of electroweak top quark production. Office of Scientific and Technical Information (OSTI), 2009. http://dx.doi.org/10.2172/965012.

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Pothen, Alex. Terascale Optimal PDE Simulations (TOPS) Center. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/890547.

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Krasnykh, Anatoly. An Improved Version of TOPAZ 3D. Office of Scientific and Technical Information (OSTI), 2003. http://dx.doi.org/10.2172/815736.

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Zimmerman, Seth. Elite Colleges and Upward Mobility to Top Jobs and Top Incomes. National Bureau of Economic Research, 2016. http://dx.doi.org/10.3386/w22900.

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