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Journal articles on the topic 'Topical gel of Sildenafil citrate'

Author: Grafiati

Published: 3 June 2025

Last updated: 1 August 2025

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1

Dhananjay, Patil* Abdurrahman Helal Ahmed Mohammed Awais Sanaurrahman Rajashri More Karishma Shrivastav Rupesh Deore Vinod Bairagi. "FORMULATION, DEVELOPMENT AND IN VITRO EVALUATION OF SILDENAFIL CITRATE LIGNOCAINE HCl GEL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 7921–37. https://doi.org/10.5281/zenodo.1403219.

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<em>The present study was undertaken to formulate, development and in vitro evaluation</em> <em>of Sildenafil Lignocaine gel</em>. <em>Sildenafil citrate is a drug of choice used in the treatment of premature ejaculation disorder</em>. <em>Topical gel has gained more and more importance because the gel based formulations are better percutaneously absorbed than creams and ointment bases</em>. <em>Therefore, topical gel of Sildenafil citrate was prepared using polymer of Carbopol 934 and triethanolamine at different proportions</em>. <em>The study encompasses compatibility studies using FTIR spe

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2

Umniyatul, Dewi, and Dwi Kurniawati Sambodo. "Identifikasi Sediaan Jamu Kuat yang Beredar di Kecamatan Banguntapan dan Pleret Kabupaten Bantul dengan Metode KLT." Surya Medika: Jurnal Ilmiah Ilmu Keperawatan dan Ilmu Kesehatan Masyarakat 14, no. 2 (2019): 103. http://dx.doi.org/10.32504/sm.v14i2.133.

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Background: Traditional herbs are ingredients or herbs in the form of plant material, animal ingredients, mineral ingredients, galenic preparations or mixtures of these ingredients, it has been used as medicine traditionally.Objective: This study is aimed to Identify of Sildenafil Citrate on “Jamu Kuat” (Herbal Medicine) products.Methods: This type of research was descriptive and the sample was determined by quota sampling. The method used Thin Layer Chromatography (TLC) which was a physicochemical method. There were seven samples were extracted by the soxhletation method until a thick extract

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Osman, Shaaban, Abobakr Yaseen, and Ahmed Mohammed. "FORMULATION AND CHARACTERIZATION OF DIFFERENT TOPICAL HYDROGELS LOADED WITH SILDENAFIL CITRATE." Al-Azhar Journal of Pharmaceutical Sciences 68, no. 2 (2023): 28–42. http://dx.doi.org/10.21608/ajps.2023.332165.

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Martyn-St James, Marrissa, Katy Cooper, Kate Ren, et al. "Topical anaesthetics for premature ejaculation: a systematic review and meta-analysis." Sexual Health 13, no. 2 (2016): 114. http://dx.doi.org/10.1071/sh15042.

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Eutectic Mixture of Local Anaesthetics (EMLA) is recommended for use off-label as a treatment for premature ejaculation (PE). Other topical anaesthetics are available, some of which have been evaluated against oral treatments. The purpose of this systematic review was to evaluate the evidence from randomised controlled trials (RCTs) for topical anaesthetics in the management of PE. Bibliographic databases including MEDLINE were searched to August 2014. The primary outcome was intra-vaginal ejaculatory latency time (IELT). Methodological quality of RCTs was assessed. IELT and other outcomes wer

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Mohamed, Soad A., Remon Roshdy Rofaeil, Hesham Salem, et al. "Proniosomal Gel-Loaded Phosphodiesterase Inhibitors (Sildenafil, Vardenafil, and Tadalafil): Prospects for Topical Penile Therapy of Tadalafil for Treatment of Erectile Dysfunction." Gels 9, no. 8 (2023): 597. http://dx.doi.org/10.3390/gels9080597.

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Oral phosphodiesterase inhibitors have emerged as a game changer for the treatment of erectile dysfunction (ED) since attaining FDA approval for its first member, sildenafil, in 1998. Topical penile therapy could be a viable replacement for oral medication that would transform the treatment of ED for many decades to come. This innovative idea could offer a safer topical alternative with less vision and cardiovascular side effects than the oral route. This work aims at developing proniosomal gels for three selected members (sildenafil, vardenafil, and tadalafil) and investigating the proniosoma

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T. Tawfeeq, Alaa, Muayad S. Abbood, and Mufeda A. Jwad. "The Comparison Between The Effect of Different Medical Drugs used To Improve Endometrial Receptivity in patients with Thin Poorly Vascularized Endometrium." IraQi Journal of Embryos and Infertility Researches 13, no. 2 (2023): 99–115. http://dx.doi.org/10.28969/ijeir.v13.i2.r8.23.

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In a perfect world, the peak of receptivity of the endometrial lining would occur simultaneously with the entry into the uterine cavity of a healthy blastocyst, which would then be able to adhere, attach, invade, and develop protected until the time of delivery. This would be the ideal scenario. The study was carried out on 200 infertile women who have thin , poorly vascularized endometrium, those patients were divided into five groups ; 40 patients in each group, group A received esterofem oral, group B received vagifem vaginal tablets, group C received sildenafil citrate gel, group D receive

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7

Kulshrestha, Shweta, Raman Chawla, Md Tanjim Alam, J. S. Adhikari, and Mitra Basu. "Efficacy and dermal toxicity analysis of Sildenafil citrate based topical hydrogel formulation against traumatic wounds." Biomedicine & Pharmacotherapy 112 (April 2019): 108571. http://dx.doi.org/10.1016/j.biopha.2019.01.032.

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Umamaheswari. D, Senthil Prabhu. R, Vinodha.G, et al. "Formulation and invitro characterization of tofacitinib citrate emulsion based gel for topical delivery." International Journal of Pharmaceuticals and Health Care Research 12, no. 4 (2024): 492–500. https://doi.org/10.61096/ijphr.v12.iss4.2024.492-500.

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The transdermal route of drug administration is an effective approach for managing various indications. This study aimed to develop a Tofacitinib citrate emulgel to achieve systemic effects, minimize side effects, and reduce the frequency of administration. Tofacitinib citrate, a Janus kinase (JAK) inhibitor, is commonly used to treat atopic dermatitis, psoriasis, and rheumatoid arthritis. The emulgel formulation incorporated liquid paraffin, Tween 80, Span 80, propylene glycol, Carbopol 940, and suitable preservatives. The concentrations of liquid paraffin (1 ml) and Carbopol 940 (150 mg) wer

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Suza Ali, H. M., B. A. Kamal, N. A. Abdalrazaq, and H. M. Mohammed. "Formulation and Evaluation of Orphenadrine Citrate as a Model Drug for Topical Hydrogel." Journal Port Science Research 8, no. 1 (2025): 54–61. https://doi.org/10.36371/port.2025.1.10.

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Orphenadrine Citrate is a muscle relaxant, act as an anti- cholinergic drug and used in the treatment of Parkinson’s disease. The objective of this study was to design a topical hydrogel formulation using Orphenadrine Citrate as a model drug. The topical administration is an alternative route that can minimize the side effects and may improve patient drug delivery. Different formulas were prepared using different gelling agents with different concentrations, CMC (1, 2 and 3% w/w), Xanthan gum (0.5, 1 and 1.5% w/w) and HPMC K40 (2, 2.5 and 3% w/w). The prepared formulas were evaluated for physi

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Sadab, Sadab, Sarad Sahu, Shubham Patel, et al. "A Comprehensive Review: Transdermal Drug Delivery System: A Tool For Novel Drug Delivery System." Asian Journal of Dental and Health Sciences 2, no. 4 (2022): 40–47. http://dx.doi.org/10.22270/ajdhs.v2i4.24.

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In the recent decade, skin delivery (topical and transdermal) has gained an unprecedented popularity, especially due to increased incidences of chronic skin diseases, demand for targeted and patient compliant delivery and interest in life cycle management strategies among pharmaceutical companies. Transdermal drug delivery system was presented to overcome the difficulties of drug delivery especially oral route. Transdermal drug delivery refers to a means of delivering drugs through the surface of the skin for local or systemic treatment. The drug functions after absorption through the skin int

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Deepika, V., and S. Srinu Naik. "Tofacitinib Citrate-Loaded Topical Gel for the Treatment of Rheumatoid Arthritis: Formulation and In-vitro-In-vivo Characterization." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 03 (2024): 1366–71. http://dx.doi.org/10.25258/ijpqa.15.3.43.

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This study aims to create and assess the anti-arthritic activity of tofacitinib citrate (TC) as a topical gel formulation. Using the gelling agent Carbopol 980 P, seven gel formulations were formed. The gel formulations were assessed for pH, drug content, spreadability, homogeneity, and in-vitro diffusion profile. Out of all the formulations, G7 exhibited superior release characteristics (99.1%) in comparison to the other formulations. The DSC research revealed a strong endothermal peak at 214.17°C and demonstrated an interaction with the excipients taken into consideration in this investigati

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12

Mostafa, Heba Abdo, Ibrahim fathi Fouda, and Hassan Khodair. "Evaluation of the Efficacy and Safety of Topical Sildenafil Citrate Solution in the Treatment of Female Pattern Hair Loss." International Journal of Medical Arts 7, no. 1 (2025): 5274–79. https://doi.org/10.21608/ijma.2024.256552.1894.

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13

Abdulkader, Omar Saleh, Abdulkareem Hameed Abd, and Ahmed Najim Abood. "Formulation and Characterization of Sodium Fusidate Loaded-Silver Nanoparticles as Gel for Topical Applications." Journal of Pioneering Medical Science 13, no. 4 (2024): 138–40. http://dx.doi.org/10.61091/jpms202413421.

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Background: The application of topical medications to facilitate the healing process and prevent infection continues to be an essential component of treatment for all types of wounds. Methods: Silver nanoparticles loaded with sodium fusidate were produced through chemical reduction using trisodium citrate as the reducing agent. The silver nanoparticles were initially produced and then incorporated into a gel prepared using carbomer 940 and triethanolamine. The sodium fusidate-loaded silver nanoparticles were characterized by pH, polydispersity index (PDI), and globular diameter. Results: The n

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14

Sharannavar, B., M. Bhagat Amonkar, Apurva Deo, Shailendra Suryawanshi, and Nithyanand Sastry Darbha. "Simultaneous Estimation of Minoxidil and Tofacitinib Citrate in Bulk and Topical Gel - A Validated UV-spectrophotometric Technique." Advances in Pharmacology and Pharmacy 13, no. 1 (2025): 37–49. http://dx.doi.org/10.13189/app.2025.130105.

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15

Alyami, Mohammad H., Hamad S. Alyami, Abdullah A. Alshehri, Wijdan K. Alsharif, Ibrahim Ahmed Shaikh, and Thamer S. Algahtani. "Tamoxifen Citrate Containing Topical Nanoemulgel Prepared by Ultrasonication Technique: Formulation Design and In Vitro Evaluation." Gels 8, no. 7 (2022): 456. http://dx.doi.org/10.3390/gels8070456.

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The present study aims to design and develop a nanoemulgel formulation of Tamoxifen citrate (TAM), a water-insoluble, potent anticancer drug, using the spontaneous emulsification method to improve topical delivery, achieve high accumulation at the tumour site, and spare the healthy tissues. The oil-based selection was related to the TAM solubility, while the surfactant and co-surfactant were chosen based on the droplets’ thermodynamic stability and size. Afterwards, a pseudo-ternary phase diagram was built for the most promising formulation using two oils, olive and sesame, with a varied mix o

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16

Dubey, Rupal, and Umadoss Pothuvan. "Transdermal patches: an emerging mode of drug delivery system in pulmonary arterial hypertension." Journal of Drug Delivery and Therapeutics 11, no. 4-S (2021): 176–86. http://dx.doi.org/10.22270/jddt.v11i4-s.4925.

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Transdermal Patches have been contributing important part to the pharmaceutical industry and medical practice by providing advances in delivery of treatment with existing and novel drugs. Transdermal drug delivery system has made great contribution in the medical practices but many researches are undergoing to achieve its full potential. Transdermal drug delivery system was came into existence to overcome difficulties of drug delivery especially oral route. Transdermal drug delivery refers to means of delivering drugs through the surface of the skin for local or systemic treatment. The drug fu

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17

López Jornet, Pia, Laureano Hernandez, Francisco Gomez García, Fe Galera Molero, Eduardo Pons-Fuster López, and Asta Tvarijonaviciute. "A Clinical Study on the Efficacy and Tolerability of a New Topical Gel and Toothpaste in Patients with Xerostomia: A Randomized Controlled Trial." Journal of Clinical Medicine 10, no. 23 (2021): 5641. http://dx.doi.org/10.3390/jcm10235641.

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Objective: xerostomia is a very common problem in the general population. The objective of this study was to determine the efficacy of a new gel and toothpaste in patients with xerostomia, analyze the role of salivary cytokines as biomarkers of xerostomia and assess the possible changes in salivary cytokines following treatment. Materials and methods: A randomized, controlled double-blind clinical study was carried out in 73 patients with xerostomia divided into two groups: placebo and active treatment (cymenol; tocopheryl acetate; D-panthenol; Aloe barbadensis; citrate tribasic dihydrate; flu

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18

Park, Jun-Soo, Jun-Hyuk Choi, Min-Yeong Joung, et al. "Design of High-Payload Ascorbyl Palmitate Nanosuspensions for Enhanced Skin Delivery." Pharmaceutics 16, no. 2 (2024): 171. http://dx.doi.org/10.3390/pharmaceutics16020171.

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A high-payload ascorbyl palmitate (AP) nanosuspension (NS) was designed to improve skin delivery following topical application. The AP-loaded NS systems were prepared using the bead-milling technique, and softly thickened into NS-loaded gel (NS-G) using hydrophilic polymers. The optimized NS-G system consisted of up to 75 mg/mL of AP, 0.5% w/v of polyoxyl-40 hydrogenated castor oil (Kolliphor® RH40) as the suspending agent, and 1.0% w/v of sodium carboxymethyl cellulose (Na.CMC 700 K) as the thickening agent, in citrate buffer (pH 4.5). The NS-G system was embodied as follows: long and flaky n

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19

HAKSEVEN, Musluh, Murat KAPAN, Ulas ALABALIK, and Gökhan AVŞAR. "Comparing The Effects Of Sildenafil Citrate And Dexpanthenol On Wound Healing: An Experimental Study." SDÜ Tıp Fakültesi Dergisi, July 26, 2022. http://dx.doi.org/10.17343/sdutfd.1100763.

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Objective: Wound healing is a serious problem that causes high morbidity. Different pharmacological agents have been studied to accelerate wound healing and to prevent necrosis and ischemia, and still continue to work. Topical dexpanthenol is widely used in both wound healing and various dermatological diseases. The aim of this study was to compare the effects of topical sildenafil citrate and topical dexpanthenol on wound healing in rats. Material and Methods: A total of 30 female Wistar Albino rats, weighing 200-250 gr, were used in the study. Rats were divided into 3 groups. A linear

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20

Haresmita, Perdana Priya, Arief Kusuma Wardani, and Missya Putri Kurnia Pradani. "Analysis of Sildenafil Citrate in Herbal for Men and Herbal for Stamina Enhancers Using High Performance Liquid Chromatography." Jurnal Ilmu Farmasi dan Farmasi Klinik 22, no. 1 (2025). https://doi.org/10.31942/jiffk.v22i1.11670.

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Jamu is a traditional Indonesian medicine that has been used for generations based on experience, using raw materials that have not been standardized. In accordance with existing laws and regulations, traditional medicines are prohibited from adding isolated chemicals or synthetic compounds with medicinal properties, known as medicinal chemicals (BKO). Sildenafil citrate is one of drugs that are often added to herbal medicine samples. The purpose of adding sildenafil citrate for “jamu” for men and stamina enhancers is to improve the quality and duration of consumer erections. The purpose of th

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"Preparation and in vitro Characterization of Sildenafil Citrate Oral Gel." International Journal of Pharmaceutical Research 12, sp1 (2020). http://dx.doi.org/10.31838/ijpr/2020.sp1.229.

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Camilla Magnano, Greta, Marika Quadri, Elisabetta Palazzo, et al. "3D human foreskin model for testing topical formulations of sildenafil citrate." International Journal of Pharmaceutics, November 2023, 123612. http://dx.doi.org/10.1016/j.ijpharm.2023.123612.

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23

Sumner, Scarlett M., Mandy L. Wallace, Alan T. Mulder, et al. "Development and evaluation of a novel topically applied sildenafil citrate hydrogel and its influence on wound healing in dogs." American Journal of Veterinary Research 83, no. 8 (2022). http://dx.doi.org/10.2460/ajvr.21.12.0209.

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Abstract OBJECTIVE To develop a topical sildenafil hydrogel and evaluate its effect on wound healing in dogs. ANIMALS 6 purpose-bred, sexually intact, adult Beagles. PROCEDURES Hydrogels containing sildenafil citrate, N-methyl-2-pyrrolidone, propylene glycol, and poloxamer 407 were developed. Four excision wounds were created along the dorsum of the dogs. Each wound was treated for 21 days with a nonadherent bandage (C) or with a hydrogel containing 0% (G), 5% (5S), or 10% (10S) sildenafil. Daily bandage changes with wound imaging were performed. Biopsy specimens were collected 5 times. RESULT

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DIGHE, PEARL PIRES, and H. M. TANK. "FORMULATION DEVELOPMENT AND STATISTICAL OPTIMIZATION OF A BILAYER TABLET OF BOSENTAN MONOHYDRATE AND SILDENAFIL CITRATE IN MANAGEMENT OF PULMONARY ARTERIAL HYPERTENSION." International Journal of Applied Pharmaceutics, February 12, 2019, 239–46. http://dx.doi.org/10.22159/ijap.2019v11i2.30927.

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Objective: The current study aims at fabrication of an oral bilayer matrix tablet of bosentan monohydrate and sildenafil citrate; the optimisation of their in vitro release and characterization, thereby reducing the side effects associated with bosentan, reducing dosing frequency and increasing patient compliance in the management of pulmonary arterial hypertension. Methods: Methocel K4M Premium DC2, a directly compressible HPMC grade was used as the sustained release polymer. Pregelatinised starch is used as a diluent and release modifier and sodium lauryl sulphate (SLS) as a solubilise

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SHARANNAVAR, BHUVANESHWARI, MONALI BHAGAT AMONKAR, POONAM INAMDAR, and MRUNALINI KULKARNI. "FORMULATION AND EVALUATION OF A TOPICAL GEL CONTAINING MINOXIDIL AND TOFACITINIB CITRATE FOR ALOPECIA AREATA." International Journal of Applied Pharmaceutics, September 7, 2023, 75–83. http://dx.doi.org/10.22159/ijap.2023v15i5.45798.

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Objective: The objective of the present study is to formulate and evaluate a topical gel containing Minoxidil and Tofacitinib citrate for alopecia areata. Methods: Six gels were formulated using the direct-dispersion method by using polymers in the ratio of Carbopol 934: HPMC and Carbopol 934: HPC in three different concentrations each. All the prepared gels were then characterized for its drug content, pH, Rheological measurement, Spreadibility, skin adhesion study, In vitro drug release, Ex-vivo skin permeation study and stability studies. Results: All the six formulations were evaluated for

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Mchallah, Flora J., Raphael Matinde, Adelina Thomas, et al. "Presence of Sildenafil and Tadalafil in Herbal Medicinal Products Claimed to Treat Erectile Dysfunction in Nyamagana and Ilemela Districts, Mwanza, Tanzania." BioMed Research International 2025, no. 1 (2025). https://doi.org/10.1155/bmri/8222227.

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Background: Herbal products are increasingly utilized for various conditions, including erectile dysfunction (ED), due to their minimal side effects, affordability, and natural properties. Phosphodiesterase type 5 inhibitors (PDE 5is) such as sildenafil citrate, tadalafil, vardenafil hydrochloride, and avanafil are synthetic oral medications approved for ED treatment. However, multiple studies have highlighted the contamination of herbal aphrodisiacs with PDE 5i or their conventional analogs. This study evaluated the contamination of aphrodisiac‐claimed herbal products available in Mwanza, Tan

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Alaa Tahir Tawfeeq, Muayad Sraibet Abbood, and Mufeda Ali Jwad. "Correlation Between Vascularity Index And Pregnancy Rate During Improve Endometrial Receptivity In Thin Poorly Vascularized Endometrium Therapy." Journal of Pharmaceutical Negative Results, October 10, 2022, 227–35. http://dx.doi.org/10.47750/pnr.2022.13.s05.29.

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Background: Pregnancy has been one of life’s great mysteries. The endometrium is where life begins, and a receptive endometriumlies at the crossroads of menstruation and pregnancy.Aim of the study: To evaluate the effects of different medical drugs used routinely to improve endometrial thickness, vascularity, andpregnancy rates and to find out the best medical protocol could be used to improve endometrial thickness, vasculature, and pregnancyrate for patient with thin and poorly vascularized endometrium regardless the cause.Materials and methods: The study was carried out on 200 infertile wome

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Kuchukuntla, Mounika, Venkatesan Palanivel, and Ananthula Madhubabu. "Tofacitinib Citrate-loaded Nanoparticle Gel for the Treatment of Alopecia Areata: Response Surface Design, Formulation and In vitro-in Vivo Characterization." Recent Advances in Drug Delivery and Formulation 17 (November 22, 2023). http://dx.doi.org/10.2174/0126673878264814231106094853.

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Objective: The purpose of this research was to optimize the design and construction of nanoparticle gel (TFN-NPs) loaded with tofacitinib citrate (TFN) using poly lactic co glycolic acid (PLGA). Method: PLGA (A) as the polymer, polyvinyl alcohol (PVA) (B) as the stabilizer and stirring speed (C) as independent variables were used. TFN-NPs were prepared using single emulsion-solvent evaporation. Box Behnken Design (BBD) was used to determine the optimal component ratio of TFN-NPs based on point prediction. Results: The entrapment efficiency, particle size, and cumulative drug release of the bes

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Tawfeeq, Alaa Tahir, Muayad Sraibet Abbood, and Mufeda Ali Jwad. "comparison between the effect of different medical drugs used to improve endometrial receptivity in patients with thin poorly vascularized endometrium." International journal of health sciences, September 30, 2022. http://dx.doi.org/10.53730/ijhs.v6ns6.13119.

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Background: Pregnancy has been one of life’s great mysteries. The endometrium is where life begins, and a receptive endometrium lies at the crossroads of menstruation and pregnancy. Aim of the study: To evaluate the effects of different medical drugs used routinely to improve endometrial thickness, vascularity, and pregnancy rates and to find out the best medical protocol could be used to improve endometrial thickness, vasculature, and pregnancy rate for patient with thin and poorly vascularized endometrium regardless the cause. Materials and methods: The study was carried out on 200 infertile

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Abdelalim, Lamiaa R., Yosra S. R. Elnaggar, and Ossama Y. Abdallah. "Oleosomes Encapsulating Sildenafil Citrate as Potential Topical Nanotherapy for Palmar Plantar Erythrodysesthesia with High Ex vivo Permeation and Deposition." AAPS PharmSciTech 21, no. 8 (2020). http://dx.doi.org/10.1208/s12249-020-01862-2.

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Fontenot, Greg, and Joseph Podolski. "MP81-08 ENCLOMIPHENE CITRATE VS. TOPICAL TESTOSTERONE GEL: EFFECTS ON REPRODUCTIVE HORMONES AND SPERM PARAMETERS." Journal of Urology 197, no. 4S (2017). http://dx.doi.org/10.1016/j.juro.2017.02.2534.

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Mahajan, Hitendra S., Vikram D. Jadhao, and Sachin M. Chandankar. "Pullulan and Pluronic F-127 based in situ gel system for intranasal delivery: Development, in vitro and in vivo evaluation." Journal of Bioactive and Compatible Polymers, July 7, 2022, 088391152211102. http://dx.doi.org/10.1177/08839115221110284.

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The current work seeks to use Pullulan and Pluronic F-127 (PF-127), a new gel-forming material, for sildenafil citrate (SLC) intranasal delivery. The cold approach was used to develop an SLC-loaded in situ gel based on thermoreversible polymer PF-127 and mucoadhesive polymer Pullulan. In situ gel systems based on Pullulan responds intelligently to environmental stimuli like charge, pH, temperature, light, and redox. To achieve gelation at physiological temperature formulations were modified to have gelation temperatures lower than 34.1°C. Physical appearance and rheological measurements were u

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HANAFIAH, OLIVIA AVRIYANTI, DENNY SATRIA, AMI ANGELA HARAHAP, et al. "WOUND HEALING ACTIVITY OF BINAHONG LEAF EXTRACT NANOGEL ON ORAL TISSUES." International Journal of Applied Pharmaceutics, May 27, 2024, 29–33. http://dx.doi.org/10.22159/ijap.2024.v16s2.07.

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Objective: The objective of the present study is to formulate and evaluate a topical gel containing minoxidil and tofacitinib citrate for alopecia areata. Methods: Forty-eight rat males were given treatment using 3% binahong leaf extract nanogel (twelve rats given palatal wound, twelve rats mandibular tooth extraction) and nanogel base (same with the amount used to extract). On palatal wounds, as many as four rats were in euthanasia on days third, seven, and fourteen for each group treatment. Whereas on the extraction groups, four rats were in euthanasia on days seventh, fourteen, and twenty-e

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"The Pattern of NSAIDs Drugs Use by Libyans Patients for Acute Tissue Injury." International Internal Medicine Journal 1, no. 2 (2023). http://dx.doi.org/10.33140/iimj.01.02.04.

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Introduction: NSAIDs are a family of drugs that have achieved widespread use in sports medicine in both prescription and over-the counter (OTC) forms. NSAIDs are often administered after acute soft tissue injury in an effort to reduce pain and inflammation and thus speed an injured athlete's return to competition. However, recent evidence suggests that the short term benefits of NSAID therapy may adversely affect the long-term healing of injured soft tissues. Method: The study was performed to test pattern of NSAIDs use by Libyan patients. Patients were asked to complete a self-report question

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jackleo. "How Do Erectile Dysfunction and Hemorrhoids Cause It?" April 18, 2025. https://doi.org/10.5281/zenodo.15239141.

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Hemorrhoids and erectile dysfunction are associated; this is a frequently discussed topic.  Although the link between hemorrhoids and erectile dysfunction is not completely clear, it is strong.  As a result, hemorrhoids indirectly contribute to erectile dysfunction, or you might claim that they are linked. <strong>Vidalista professional</strong> might help you regain an erection and treat erectile dysfunction.  Research is needed to determine whether the medicine can treat hemorrhoids in addition to ED.  Before learning about the relationship between ED and piles, you shoul

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