Relevant bibliographies by topics / Total genotype score TGS

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Academic literature on the topic 'Total genotype score TGS'

Author: Grafiati
Published: 4 June 2025
Last updated: 20 July 2025

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Journal articles on the topic "Total genotype score TGS"

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Pranckeviciene, Erinija, Valentina Gineviciene, Audrone Jakaitiene, Laimonas Januska, and Algirdas Utkus. "Total Genotype Score Modelling of Polygenic Endurance-Power Profiles in Lithuanian Elite Athletes." Genes 12, no. 7 (2021): 1067. http://dx.doi.org/10.3390/genes12071067.

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Total genotype score (TGS) reflects additive effect of genotypes on predicting a complex trait such as athletic performance. Scores assigned to genotypes in the TGS should represent an extent of the genotype’s predisposition to the trait. Then, combination of genotypes highly ranks those individuals, who have a trait expressed. Usually, the genotypes are scored by the evidence of a genotype–phenotype relationship published in scientific studies. The scores can be revised computationally using genotype data of athletes, if available. From the available genotype data of 180 Lithuanian elite athl
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Homma, Hiroki, Mika Saito, Aoto Saito, et al. "The Association between Total Genotype Score and Athletic Performance in Weightlifters." Genes 13, no. 11 (2022): 2091. http://dx.doi.org/10.3390/genes13112091.

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This study aimed to investigate the relationship between power-oriented genetic polymorphisms and weightlifting status, create a total genotype score (TGS), and validate the association between TGS models and power-oriented athletes. First, 192 weightlifters and 416 controls were studied, and 12 polymorphisms that have previously been associated with strength, power status, and phenotype were genotyped using the TaqMan SNP genotyping assay. We calculated the TGS for the 12 polymorphisms using a PWM (power-oriented whole model) and for 6 of them using a WRM (weightlifting-related model) based o
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Ab Wahab, Wan Atiyyah, Sarina Md Yusof, Lay Kek Teh, Suhana Aiman, Elin Elisa Khairul, and Nur Amirah Asyiqin Zaihuri. "CORRELATION OF TOTAL GENOTYPE SCORES AND AEROBIC CAPACITY AMONG FIELD HOCKEY PLAYERS." Malaysian Journal of Sport Science and Recreation 18, no. 2 (2022): 161–78. http://dx.doi.org/10.24191/mjssr.v18i2.19555.

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A balanced aerobic and anaerobic capacity is an important determinant of performance among field hockey players during the competition. Training and heritable talent play important roles in determining the performance of the athletes. Therefore, this study aimed to investigate the influence of sport-related genetic variants on aerobic capacity and repeated sprint ability performance among field hockey players. A total of 45 participants (age = 16.42 ± 0.50 years old, height = 1.67 ± 0.06 m) were selected based on the inclusion criteria of this study. Participants were divided into three groups
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Vostrikova, Anna, Victoria Pechenkina, Maria Danilova, Svetlana Boronnikova, and Ruslan Kalendar. "Gene Polymorphism and Total Genetic Score in Martial Arts Athletes with Different Athletic Qualifications." Genes 13, no. 9 (2022): 1677. http://dx.doi.org/10.3390/genes13091677.

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The personalized approach in sports genetics implies considering the allelic variants of genes in polymorphic loci when adjusting the training process of athletes. The personalized approach is used both in sports genetics and in medicine to identify the influence of genotype on the manifestations of human physical qualities that allow to achieve high sports results or to assess the impact of genotype on the development and course of diseases. The impact of genes of the renin-angiotensin and kinin-bradykinin systems in the development of cardiovascular disease in athletes has not been defined.
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Khairul, Elin Elisa, Wan Atiyyah Ab Wahab, Lay Kek Teh, et al. "The Predictive Ability of Total Genotype Score and Serum Metabolite Markers in Power-Based Sports Performance Following Different Strength Training Intensities — A Pilot Study." Pertanika Journal of Science and Technology 31, no. 2 (2023): 1087–103. http://dx.doi.org/10.47836/pjst.31.2.23.

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Muscular power is one of the factors that contribute to an athlete’s performance. This study aimed to explore the predictive ability of total genotype score (TGS) and serum metabolite markers in power-based sports performance following different strength training (ST) intensities. We recruited 15 novice male field hockey players (age = 16.27 ± .12 years old, body mass index = 22.57 ± 2.21 kg/m2) and allocated them to; high-intensity strength training (HIST, n=5), moderate intensity strength (MIST, n=5), and control group (C, n=5). Both training groups completed an eight-week ST intervention. P
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Malyutkina, A., V. Kardakova, M. Burlutskaya, E. Gavrikova, and S. Boronnikova. "Allelic options of genes ACE, PPARG and PPARGC1A at martial artists of the city of Perm." Bulletin of Science and Practice 4, no. 12 (2018): 125–33. https://doi.org/10.5281/zenodo.2255526.

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Genotyping of 143 athletes of the martial artist at three sports schools of Perm aged from 9 up to 20 years is carried out. With use of PCR method allelic options of genes of ACE, PPARG and PPARGC1A are revealed; their frequencies and genotypes are determined. The polymorphisms of I/D of a gene of ACE (angiotensin I converting enzyme) is studied, and also a polymorphism of Pro12→Ala of a gene of PPARG (peroxisome proliferator-activated receptor gamma) and a polymorphism of Gly482Ser of a gene of PPARGC1A (peroxisome proliferator-activated receptor gamma coactivator 1–alpha) are esta
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Varillas-Delgado, David, Juan José Tellería Orriols, and Juan Del Coso. "Genetic Profile in Genes Associated with Cardiorespiratory Fitness in Elite Spanish Male Endurance Athletes." Genes 12, no. 8 (2021): 1230. http://dx.doi.org/10.3390/genes12081230.

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Background: most of the research concerning the influence of genetics on endurance performance has been carried out by investigating target genes separately. However, endurance performance is a complex trait that can stem from the interaction of several genes. The objective of this study was to compare the frequencies of polymorphisms in target genes involving cardiorespiratory functioning in elite endurance athletes vs. non-athlete controls. Methods: genotypic frequencies were determined in 123 elite endurance athletes and in 122 non-athletes. Genotyping of ACE (rs4340), NOS3 (rs2070744 and r
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Freitas, Nei Adão Ribeiro de, Simone Mader Dall Agnol, Cristiana Magni, Paulo Roberto da Silva, Cesar Augusto de Souza Santos, and Luis Paulo Gomes Mascarenhas. "Comparação entre o polimorfismo do gene Apoe na composição corporal, potência muscular e Total Genotype Score (TGS)." Revista Brasileira de Educação Física e Esporte 35, no. 4 (2021): 131–43. http://dx.doi.org/10.11606/issn.1981-4690.v35i4p131-143.

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Descrever o perfil de saúde dos grupos estudados, verificar a frequência dos alelos e dos genótipos do gene Apolipoproteína E (ApoE) e comparar os polimorfismos do gene ApoE com composição corporal, potência de membros inferiores (MMIIs) e total genotype score (TGS), a amostra foi composta por 81 indivíduos. O ácido desoxirribonucleico (ADN) foi obtido a partir de amostras do esfregaço da mucosa oral. A composição corporal foi avaliada pela balança de bioimpedância OMRON e a potência de MMIIs foi mensurada pelo tapete de contato da Hidrofit, com os testes Squat jump (SJ) e Counter moviment jum
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Gómez-Gallego, Félix, Jonatan R. Ruiz, Amaya Buxens, et al. "Are elite endurance athletes genetically predisposed to lower disease risk?" Physiological Genomics 41, no. 1 (2010): 82–90. http://dx.doi.org/10.1152/physiolgenomics.00183.2009.

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We compared a polygenic profile that combined 33 disease risk-related mutations and polymorphisms among nonathletic healthy control subjects and elite endurance athletes. The study sample comprised 100 healthy Spanish male nonathletic (sedentary) control subjects and 100 male elite endurance athletes. We analyzed 33 disease risk-related mutations and polymorphisms. We computed a health-related total genotype score (TGS, 0–100) from the accumulated combination of the 33 variants. We did not observe significant differences in genotype or allele distributions among groups, except for the rs4994 p
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Pagliaro, Andrea, Anna Alioto, Alessia Boatta, et al. "Genetic Profiling and Performance Optimization in Elite Combat Sport Athletes: A Cross-Sectional Study Based on Total Genetic Score Analysis." Genes 16, no. 4 (2025): 461. https://doi.org/10.3390/genes16040461.

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Background/Objectives: The interplay between genetics and athletic performance has garnered significant attention, particularly regarding performance-enhancing polymorphisms (PEPs) and their role in determining key traits that are critical for athletic success. Therefore, this study investigates the genetic predispositions related to peroxisome proliferator-activated receptor alpha (PPARα), angiotensin converting enzyme (ACE), and creatine kinase muscle-type (CKM) gene variants and their potential influence on elite point-fighting (PF) athletes. Methods: A total of 24 elite PF athletes (12 wom
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Dissertations / Theses on the topic "Total genotype score TGS"

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Guilherme, João Paulo Limongi França. "Perfil poligênico de atletas brasileiros: distribuição de polimorfismos associados ao desempenho físico." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/39/39132/tde-10042017-134032/.

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A partir da finalização do projeto genoma humano, fornecendo informação sobre o código genético de um indivíduo referência, pesquisadores direcionam a busca por sítios polimórficos existentes no DNA genômicos e mitocondrial capazes de influenciar direta ou indiretamente traços relevantes nas mais diversas áreas. No esporte esta busca tem sido direcionada para identificar marcadores genéticos associados aos fenótipos envolvidos com o desempenho físico (endurance vs. força e potência muscular). Atualmente, diversos polimorfismos foram associados ao desempenho físico-esportivo, em pelo menos um e
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