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Dissertations / Theses on the topic 'Total Internal Reflection Raman Spectroscopy'

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1

Finzer, Brant M. "Detection of Oxyanion Adsorption at the Silica-Aqueous Interface using Total Internal Reflection (TIR)-Raman Spectroscopy." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417521135.

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2

Bingham, Laura Maria. "Development of nanoparticle catalysts and total internal reflection (TIR) Raman spectroscopy for improved understanding of heterogeneous catalysis." Thesis, Durham University, 2017. http://etheses.dur.ac.uk/12445/.

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Laser Raman spectroscopy has been used very effectively for some time to probe heterogeneous catalytic reactions in situ. TIR Raman is a variant of non-resonant Raman spectroscopy which uses a totally internally reflected light, i.e. an evanescent electric field acts as the excitation source. TIR Raman reduces or avoids some key limitations of bulk Raman spectroscopy, including reduction of laser induced sample damage. This thesis has therefore been investigating the possible application of TIR Raman spectroscopy to studying heterogeneous catalysts, in particular films of size controlled metal
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3

Shou, Xiao. "Low Frequency and Total Internal Reflection Raman Spectroscopic Study of Ions in Bulk and at the Silica/Aqueous Interface." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1398878470.

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4

Parsons, David. "The use of total internal reflection fluorescence spectroscopy to study polymer and particle adsorption." Thesis, University of Salford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304598.

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5

Pero, Jamie Kay Thompson Nancy L. "Advancements in methodologies and theories regarding model membrane environments by total internal reflection with fluorescence correlation spectroscopy." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,1279.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2006.<br>Title from electronic title page (viewed Mar. 27, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry." Discipline: Chemistry; Department/School: Chemistry.
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6

Yordanov, Stoyan [Verfasser]. "Total internal reflection fluorescence cross-correlation spectroscopy: theory and application for studying boundary slip phenomenon / Stoyan Yordanov." Mainz : Universitätsbibliothek Mainz, 2011. http://d-nb.info/1030030928/34.

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7

Kwok, Ka Cheung. "Measuring binding kinetics of ligands with tethered receptors by fluorescence polarization complemented with total internal reflection fluorescence microscopy." HKBU Institutional Repository, 2010. https://repository.hkbu.edu.hk/etd_oa/18.

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The study of the binding between estrogen receptors (ER) and their ligands in vitro has long been of interest mainly because of its application in anti-estrogen drug discovery for breast cancer treatment as well as in the screening of environmental contaminants for endocrine disruptors. Binding strength was conventionally quantified in terms of equilibrium dissociation constant (KD). Recently, emphasis is shifting towards kinetics rate constants, and off-rate (koff) in particular. This thesis reported a novel method to measure such binding kinetics based on fluorescence polarization complement
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8

Kerssens, Marleen Maartje. "Study of calcification formation and disease diagnostics utilising advanced vibrational spectroscopy." Thesis, Cranfield University, 2012. http://dspace.lib.cranfield.ac.uk/handle/1826/7924.

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The accurate and safe diagnosis of breast cancer is a significant societal issue, with annual disease incidence of 48,000 women and around 370 men in the UK. Early diagnosis of the disease allows more conservative treatments and better patient outcomes. Microcalcifications in breast tissue are an important indicator for breast cancers, and often the only sign of their presence. Several studies have suggested that the type of calcification formed may act as a marker for malignancy and its presence may be of biological significance. In this work, breast calcifications are studied with FTIR, sync
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9

Yiu, Kwok Wing. "Measuring the binding between estrogen receptor alpha and potential endocrine disruptors by fluorescence polarization and total internal reflection fluorescence." HKBU Institutional Repository, 2013. http://repository.hkbu.edu.hk/etd_ra/1503.

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10

Chmyrov, Andriy. "Photo-induced dark states influorescence spectroscopy – investigations & applications." Doctoral thesis, KTH, Experimentell biomolekylär fysik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-12372.

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This thesis focuses on investigations of transient dark states of fluorescentmolecules using spectroscopic techniques. The main purpose is to show andconvince the reader that transient dark states are not always a nuisance, butalso represent an additional source of information. Several studies with fluorescencecorrelation spectroscopy were performed, all related to non-fluorescentstates such as triplet state or isomerized states.Photobleaching is one of the main problems in virtually all of the fluorescencetechniques. In this thesis, mechanisms that retard photobleaching arecharacterized. Seve
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11

Menegazzo, Nicola. "A novel approach to diamondlike carbon based mid-infrared attenuated total reflectance spectroelectrochemistry." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/22616.

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Thesis (Ph. D.)--Chemistry and Biochemistry, Georgia Institute of Technology, 2007.<br>Committee Chair: Mizaikoff, Boris; Committee Member: Bottomley, Lawrence; Committee Member: Hunt, William; Committee Member: Janata, Jiri; Committee Member: Josowicz, Miroslawa.
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12

Abdalla, Hope Cook. "Investigation of Amyloid β Oligomer Dissociation Mechanisms by Single Molecule Fluorescence Techniques". UKnowledge, 2019. https://uknowledge.uky.edu/chemistry_etds/109.

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Alzheimer’s disease (AD) is currently considered the most prevalent neurodegenerative disease and places a large financial burden on society as healthcare resources are limited and the disease does not have a cure. Alzheimer’s disease is characterized by the presence of amyloid beta (Aβ) plaques and neurofibrillary tangles; however current literature suggests Aβ oligomers are the main aggregating species leading to AD symptoms. Therefore, the underlying cause of Alzheimer’s, accumulation of amyloid beta, is currently being studied in hopes of developing treatment options. Our research aims at
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13

Jasper, Evan. "Development of Techniques in Time Domain Terahertz Spectroscopy for the Study of Chiral and Topological Materials." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1597048083501651.

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14

Pu, Mingming. "Investigations of the Mechanism for Activation of Bacillus Thuringiensis Phosphatidylinositol-specific Phospholipase C." Thesis, Boston College, 2009. http://hdl.handle.net/2345/1179.

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Thesis advisor: Mary F. Roberts<br>Thesis advisor: Steven D. Bruner<br>The bacterial phosphatidylinositol-specific phospholipase C (PI-PLC) from Bacillus thuringiensis is specifically activated by low concentrations of a non-substrate lipid, phosphatidylcholine (PC), presented as an interface. However, if the PC concentration in the interface is too high relative to substrate, the enzyme exhibits surface dilution inhibition. Understanding this bacterial enzyme, which shares many kinetic features with the larger and more complex mammalian PI-PLC enzymes, requires elucidating the mechanism for P
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15

Decan, Matthew. "The Copper(I)-catalyzed Azide–Alkyne Cycloaddition: A Modular Approach to Synthesis and Single-Molecule Spectroscopy Investigation into Heterogeneous Catalysis." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31882.

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Click chemistry is a molecular synthesis strategy based on reliable, highly selective reactions with thermodynamic driving forces typically in excess of 20 kcal mol-1. The 1,3-dipolar cycloaddition of azides and alkynes developed by Rolf Huisgen saw dramatic rate acceleration using Cu(I) as a catalyst in 2002 reports by Barry Sharpless and Morten Meldal enabling its click chemistry eligibility. Since these seminal reports, the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) has become the quintessential click reaction finding diverse utility. The popularity of the CuAAC has naturally l
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16

Morten, Michael J. "Developing novel single molecule analyses of the single-stranded DNA binding protein from Sulfolobus solfataricus." Thesis, University of St Andrews, 2015. http://hdl.handle.net/10023/7568.

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Single-stranded DNA binding proteins (SSB) bind to single-stranded DNA (ssDNA) that is generated by molecular machines such as helicases and polymerases. SSBs play crucial roles in DNA translation, replication and repair and their importance is demonstrated by their inclusion across all domains of life. The homotetrameric E. coli SSB and the heterotrimeric human RPA demonstrate how SSBs can vary structurally, but all fulfil their roles by employing oligonucleotide/oligosaccharide binding (OB) folds. Nucleofilaments of SSB proteins bound to ssDNA sequester the ssDNA strands, and in doing so pro
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17

Do, Le Duy. "Relation entre l’annexine A6 et la phospholipase D1 pendant le processus d’exocytose dans les cellules PC12." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10160/document.

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L'exocytose régulée, est un processus qui permet la communication entre les cellules à travers la sécrétion des hormones et des neurotransmetteurs. Dans les neurones et les cellules neuroendocrines, l'exocytose est strictement contrôlée par des signaux extracellulaires tels que le potentiel trans-membranaire et la fixation des ligands sur des récepteurs. Des progrès substantiels ont été effectués afin de comprendre le mécanisme moléculaire de l'exocytose. Les composants majeurs de la machinerie de sécrétion ont été dévoilés. Maintenant, la question qui émerge concerne le rôle de la plateforme
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18

Praveena, M. "Design, Fabrication and Application of In situ Total Internal Reflection (TIR) Raman Tribometer For the Chemical Analysis of Tribological Systems." Thesis, 2013. https://etd.iisc.ac.in/handle/2005/4581.

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In conventional tribological experiments that study friction and wear behavior of materials, the contact interface is hidden by the contacting bodies. The physical or chemical phenomena taking place at the interface must then be examined through intermittent tests. These kinds of postmortem studies have remained speculative and model based. The inadequacy of such analysis has long been recognized. For a fundamental understanding of interfacial phenomena, it is important to study interactions in real-time. The present work attempts to overcome this hidden-interface problem by developing a tribo
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19

Kraning, Casey M. "A comparison of the surface adsorption characteristics of reduced and oxidized cytochrome c on a fused silica surface via attenuated total internal reflection spectroscopy /." 2008. http://digitalcommons.butler.edu/ugtheses/54/.

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Thesis (B.S.) Summa Cum Laude--Butler University, 2008.<br>Includes curriculum vitae. Appendix 2 includes the article: Kraning CM, Benz TL, Bloome KS, Campanello GC, Fahrenbach VS, Mistry SA, Hedge CA, Clevenger KD, Gligorich KM, Hopkins TA, Hoops GC, Mendes SB, Chang H-C, Su M-C (2007) Determination of surface coverage and orientation of reduced cytochrome c on a silica surface with polarized ATR spectroscopy. J. Phys. Chem. C 2007, 111:13062-13067. Includes bibliographical references (88-91).
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