Academic literature on the topic 'Total Intravenous Anesthesia (TIVA)'

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Journal articles on the topic "Total Intravenous Anesthesia (TIVA)"

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Kannabiran, Narmadhalakshmi, and Prasanna Udupi Bidkar. "Total Intravenous Anesthesia in Neurosurgery." Journal of Neuroanaesthesiology and Critical Care 05, no. 03 (2018): 141–49. http://dx.doi.org/10.1055/s-0038-1673544.

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AbstractIn recent years, neurosurgical anesthesia has been rapidly evolving in the fields of pharmacotherapy and techniques to administer safe anesthesia. Intravenous (IV) anesthetic agents reduce both cerebral blood flow and intracranial pressure besides maintaining flow–metabolism coupling in contrast to inhalational agents. In neuroanesthesia, the technique and choice of drugs directly influence the outcome of the patients. The purpose of this review is to provide the updated information of total intravenous anesthesia (TIVA) in neuroanesthesia. Administration of TIVA using target-controlled infusion technique is emerging as a standard method to administer safe anesthesia in neurosurgical patients. The propofol–remifentanil combination has become very popular due to their favorable pharmacokinetic and pharmacodynamic properties for neurosurgery cases. Plasma-effect site concentration monitoring from target TCI devices together with electroencephalogram or bispectral index monitors allows easy titration of anesthetic agents to ensure adequate depth of anesthesia depending upon the nociceptive stimulus. TIVA is associated with smooth induction and rapid emergence with less postoperative nausea and vomiting.
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Anna Abad - Torrent. "Recomendaciones para la práctica segura de la Anestesia Total Intravenosa." Revista Electrónica AnestesiaR 12, no. 6 (2020): 2. http://dx.doi.org/10.30445/rear.v12i6.853.

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Wong, Grace L. S., and Neil S. Morton. "Total intravenous anesthesia (TIVA) in pediatric cardiac anesthesia." Pediatric Anesthesia 21, no. 5 (2011): 560–66. http://dx.doi.org/10.1111/j.1460-9592.2011.03565.x.

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LERMAN, JERROLD, and MARTIN JÖHR. "Inhalational anesthesia vs total intravenous anesthesia (TIVA) for pediatric anesthesia." Pediatric Anesthesia 19, no. 5 (2009): 521–34. http://dx.doi.org/10.1111/j.1460-9592.2009.02962.x.

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Toscano, Fiore V., Angela K.Vick, Hamilton H. Shay, and Ellise S. Delphin. "Total Intravenous Anesthesia (TIVA) for Stiff-Person Syndrome." Open Journal of Anesthesiology 02, no. 04 (2012): 185–87. http://dx.doi.org/10.4236/ojanes.2012.24042.

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Velázquez-Delgado, Perla I., Eduardo Gutierrez-Blanco, Felipe de J. Torres-Acosta, Antonio Ortega-Pacheco, Armando J. Aguilar-Caballero, and Brighton T. Dzikiti. "Comparison of Propofol or Isoflurane Anesthesia Maintenance, Combined with a Fentanyl–Lidocaine–Ketamine Constant-Rate Infusion in Goats Undergoing Abomasotomy." Animals 11, no. 2 (2021): 492. http://dx.doi.org/10.3390/ani11020492.

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This study aimed to compare, first, the anesthetic and cardiopulmonary effects of propofol or isoflurane anesthetic maintenance in goats receiving a fentanyl–lidocaine–ketamine infusion undergoing abomasotomy and, secondly, to compare the quality of the recovery from anesthesia. Two groups were used: propofol (TIVA) and isoflurane (PIVA). Goats were premedicated with fentanyl (10 μg/kg intravenously [IV]), lidocaine (2 mg/kg, IV), and ketamine (1.5 mg/kg, IV). Anesthesia was induced with propofol and maintenance consisted of fentanyl (10 μg/kg/h, IV), lidocaine (50 μg/kg/min, IV), and ketamine (50 μg/kg/min, IV) as constant-rate infusions (CRIs), combined with either CRI of propofol at initial dose of 0.3 mg/kg/min, IV (TIVA), or isoflurane with initial end-tidal (FE’Iso) concentration of 1.2% partial intravenous anesthesia (PIVA). The mean effective propofol dose for maintenance was 0.44 ± 0.07 mg/kg/min, while the mean FE’Iso was 0.81 ± 0.2%. Higher systolic arterial pressure (SAP) values were observed in total intravenous anesthesia (TIVA) during some time points. Recovery was smooth in PIVA, while restlessness, vocalizations, and paddling were observed in TIVA. Both protocols produced a satisfactory quality of anesthesia during surgery, with minimal impact on cardiopulmonary function. Nevertheless, recovery after anesthesia in TIVA might be of poor quality.
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Chokshi, Tushar M. "Infographics in TIVA." Journal of Cardiac Critical Care TSS 05, no. 01 (2021): 033–42. http://dx.doi.org/10.1055/s-0041-1723628.

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AbstractInfographics are a new way of visually communicating information in a colorful and concise manner. They are becoming very popular in medical field since the last decade. Through infographics, one can understand the subjects through text, graphics, and images. Total intravenous anesthesia (TIVA) is a technique of general anesthesia (GA) given via intravenous (IV) route exclusively. In perspective of infographics, TIVA is far more understandable through its simple format. TIVA is also more advantageous than inhalational anesthesia. It avoids the deleterious effects of immunosuppressant and lacks any respiratory irritation, thus providing a good alternative anesthesia technique. Many peripheral surgeries can be done with the patient breathing spontaneously without any airway device, thus avoiding airway instrumentation, leading to droplet and aerosol generation. IV agents can be utilized to provide sedation during regional anesthesia (RA), which can easily be escalated to contain pain due to sparing of blocks or receding neuraxial anesthesia. The present narrative review focuses on the infographics in TIVA technique, providing highlights pertaining to its importance.
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Visser, Klazina, Elly A. Hassink, Gouke J. Bonsel, Jeroen Moen, and Cor J. Kalkman. "Randomized Controlled Trial of Total Intravenous Anesthesia with Propofol versus Inhalation Anesthesia with Isoflurane–Nitrous Oxide." Anesthesiology 95, no. 3 (2001): 616–26. http://dx.doi.org/10.1097/00000542-200109000-00012.

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Background To assess the incidence of postoperative nausea and vomiting after total intravenous anesthesia (TIVA) with propofol versus inhalational anesthesia with isoflurane-nitrous oxide, the authors performed a randomized trial in 2,010 unselected surgical patients in a Dutch academic institution. An economic evaluation was also performed. Methods Elective inpatients (1,447) and outpatients (563) were randomly assigned to inhalational anesthesia with isoflurane-nitrous oxide or TIVA with propofol-air. Cumulative incidence of postoperative nausea and vomiting was recorded for 72 h by blinded observers. Cost data of anesthetics, antiemetics, disposables, and equipment were collected. Cost differences caused by duration of postanesthesia care unit stay and hospitalization were analyzed. Results Total intravenous anesthesia reduced the absolute risk of postoperative nausea and vomiting up to 72 h by 15% among inpatients (from 61% to 46%, P < 0.001) and by 18% among outpatients (from 46% to 28%, P < 0.001). This effect was most pronounced in the early postoperative period. The cost of anesthesia was more than three times greater for propofol TIVA. Median duration of stay in the postanesthesia care unit was 135 min after isoflurane versus 115 min after TIVA for inpatients (P < 0.001) and 160 min after isoflurane versus 150 min after TIVA for outpatients (P = 0.039). Duration of hospitalization was equal in both arms. Conclusion Propofol TIVA results in a clinically relevant reduction of postoperative nausea and vomiting compared with isoflurane-nitrous oxide anesthesia (number needed to treat = 6). Both anesthetic techniques were otherwise similar. Anesthesia costs were more than three times greater for propofol TIVA, without economic gains from shorter stay in the postanesthesia care unit
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Cho, Ho Bum, Mun Gyu Kim, Sun Young Park, et al. "The influence of propofol-based total intravenous anesthesia on postoperative outcomes in end-stage renal disease patients: A retrospective observation study." PLOS ONE 16, no. 7 (2021): e0254014. http://dx.doi.org/10.1371/journal.pone.0254014.

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Background To determine whether the anesthetic method of propofol total intravenous anesthesia (TIVA) is associated with postoperative outcome in ESRD patients, we evaluated the incidence of postoperative major adverse cardiac events (MACE), comparing propofol TIVA versus anesthesia with volatile anesthesia in ESRD patients. Methods Retrospectively, we identified cases with ESRD patients who underwent surgery under general anesthesia. Patients were divided into those who received only volatile anesthesia (volatile group) and those who received only propofol TIVA (TIVA group). The incidence of MACE and potential confounding variables were compared separately in a univariate logistic model and subsequently by multivariate logistic regression. Results Among the 2576 cases in ESRD patients, 1374 were in the TIVA group and 1202 were in the volatile group. The multivariate analysis included 12 factors, including the anesthesia method, of which five factors were significant. Factors that were associated with a significantly lower MACE risk included preoperative chloride concentration (OR: 0.96; 95% CI, 0.92–0.99), baseline SBP (OR: 0.98; 95% CI, 0.98–0.99), and propofol TIVA (OR: 0.37; 95% CI, 0.22–0.60). Conclusions We inferred that the anesthetic method associated with the postoperative outcome in patients with ESRD.
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Şen, Ahmet, Başar Erdivanlı, Abdullah Özdemir, Hızır Kazdal, and Ersagun Tuğcugil. "Efficacy of Continuous Epidural Analgesia versus Total Intravenous Analgesia on Postoperative Pain Control in Endovascular Abdominal Aortic Aneurysm Repair: A Retrospective Case-Control Study." BioMed Research International 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/205164.

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We reviewed our experience to compare the effectiveness of epidural analgesia and total intravenous analgesia on postoperative pain control in patients undergoing endovascular abdominal aortic aneurysm repair. Records of 32 patients during a 2-year period were retrospectively investigated. TIVA group (n=18) received total intravenous anesthesia, and EA group (n=14) received epidural anesthesia and sedation. Pain assessment was performed on all patients on a daily basis during rest and activity on postoperative days until discharge from ward using the numeric rating scale. Data for demographic variables, required anesthetic level, perioperative hemodynamic variables, postoperative pain, and morbidities were recorded. There were no relevant differences concerning hospital stay (TIVA group: 14.1 ± 7.0, EA group: 13.5 ± 7.1), perioperative blood pressure variability (TIVA group: 15.6 ± 18.1, EA group: 14.8 ± 11.5), and perioperative hemodynamic complication rate (TIVA group: 17%, EA group: 14%). Postoperative pain scores differed significantly (TIVA group: 5.4 ± 0.9, EA group: 1.8 ± 0.8,P<0.001). Epidural anesthesia and postoperative epidural analgesia better reduce postoperative pain better compared with general anesthesia and systemic analgesia, with similar effects on hemodynamic status.
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Dissertations / Theses on the topic "Total Intravenous Anesthesia (TIVA)"

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Bulow, Neusa Maria Heinzmann. "Dexmedetomidina diminui a resposta inflamatória após cirurgia miocárdica sob mini-circulação extracorpórea." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/4472.

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Despite great technological advances in coronary artery bypass grafting (CABG) surgery, there is a high incidence of cardiac dysfunction and neurocognitive deficits in the postoperative period. Preventive measures are essential to reducing these adverse situations that are responsible for significant morbidity and impairment on life quality of these patients. Surgery and cardiopulmonary bypass (CPB) produces important changes in the immune system, directly involved in the incidence of these complications and is credible that anesthesia choice can it modified. We hypothezised that dexmedetomidine, an (α)-2-agonist, could the inflammatory response to CABG and CPB modified. In a prospective and randomized study, we intend to demonstrate the influence of dexmedetomidine (TIVA-DEX group), as a component of a conventional total intravenous anesthesia (TIVA-propofol+sufentanil) in patients undergoing CABG, with mini-CPB, on the behavior of this inflammatory response. The TIVA-DEX group received a continuous infusion of dexmedetomidine associated to a conventional venous anesthesia (continuous infusion of propofol+sufentanil). Intraoperative dosage of cytokines, such as interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-10 (IL-10), gamma interferon (INF-γ) and tumor necrosis factor (TNF-α) were performed, and also C-reactive protein (CRP), creatine phosphokinase (CPK), creatine phosphokinase-MB (CPK-MB), I troponin (cTnI), cortisol and glucose. The occurrence of lipid peroxidation, by the study of thiobarbituric acid reactive substances (TBARS) and the activity of delta-aminolevulinate dehydratase (δ-ALA-D) to oxidative stress verify were also avaliated. Dexmedetomidine induce a significative reduction of IL-1, IL-6, TNF-α and INF-γ, as compared to group that not receive dexmedetomidine. The levels of IL-10 were decreased in both groups along the time, at a similar pattern. Differences between groups on δ-ALA-D activity do not occur and TBARS was higher in TIVA-DEX group. We concluded that dexmedetomidine associated to TIVA was able to reduce plasma levels of proinflammatory cytokines IL-1, IL-6, TNF-α and INF-γ in patients submitted to CABG surgery under mini-CPB, as compared to a conventional TIVA. These results reinforce literature data about dexmedetomidine potentiality as an anti inflammatory agent.<br>Apesar dos grandes avanços tecnológicos nas cirurgias de revascularização miocárdica (CRM), ocorre uma grande incidência de disfunção cardíaca e déficit neurocognitivo no período pós-operatório. As medidas preventivas são essenciais para a redução destas situações adversas, responsáveis pelo comprometimento da qualidade de vida dos pacientes. A cirurgia e a circulação extra-corpórea (CEC) produzem alterações importantes no sistema imunológico, diretamente envolvidas na incidência das complicações e acredita-se que a escolha anestésica possa modificá-las. Em estudo prospectivo e randomizado, pretendemos demonstrar a influência da dexmedetomidina (grupo AIVT-DEX), um anestésico (α)-2-agonista, associado à anestesia intravenosa total (AIVT) no comportamento da resposta inflamatória em pacientes submetidos à CRM, sob mini-circulação extracorpórea (mini-CEC). O grupo AIVT-DEX recebeu infusão contínua de dexmedetomidina associado à técnica de AIVT convencional e o outro grupo foi submetido à AIVT convencional (infusão contínua de propofol e sufentanil). Os grupos foram comparados pela dosagem plasmática trans-operatória de citocinas, como a interleucina-1(IL-1), a interleucina-6 (IL-6), a interleucina-10 (IL-10), o interferon gama (INF-γ) e o fator de necrose tumoral alfa (TNF-α), bem como a proteína C reativa (PCR), creatinofosfoquinase (CPK), creatinofosfoquinase miocárdio específica (CPK-MB), troponina I (cTnI), cortisol e glicose. A peroxidação lipídica foi avaliada pelo estudo das substâncias reativas ao ácido tiobarbitúrico (TBARS) e a presença de estresse oxidativo pela atividade da enzima delta-aminolevulinato desidratase (δ-ALA-D). O uso da dexmedetomidina induziu redução significativa de IL-1, IL-6, TNF-α e INF-γ se comparado ao grupo sem dexmedetomidina. Houve redução progressiva dos níveis de IL-10 ao longo do tempo, de forma semelhante entre os grupos. Não houve diferença entre os grupos para a atividade da enzima δ-ALA-D e os níveis de TBARS foram maiores no grupo AIVT-DEX. Concluímos que a dexmedetomidina associada à AIVT convencional foi capaz de reduzir os níveis plasmáticos das citocinas pró-inflamatórias IL-1, IL-6, TNF-α e INF-γ em pacientes submetidos à CRM sob mini-CEC, se comparados aos pacientes que receberam apenas a AIVT convencional. Estes resultados reforçam os dados da literatura quanto à potencialidade da dexmedetomidina como agente modulador da resposta inflamatória no período trans- operatório.
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Menezes, Daniel Carvalho de [UNESP]. "Utilização do sufentanil durante indução anestésica em anestesia venosa total com remifentanil em infusão contínua." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/137901.

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Submitted by DANIEL CARVALHO DE MENEZES null (menezesdcc@hotmail.com) on 2016-04-11T00:33:09Z No. of bitstreams: 1 Dissertação - Mestrado - Daniel Carvalho de Menezes.pdf: 1004576 bytes, checksum: ed91db99176a44b0b049ca9ff16a1a70 (MD5)<br>Approved for entry into archive by Ana Paula Grisoto (grisotoana@reitoria.unesp.br) on 2016-04-12T17:59:09Z (GMT) No. of bitstreams: 1 menezes_dc_me_bot.pdf: 1004576 bytes, checksum: ed91db99176a44b0b049ca9ff16a1a70 (MD5)<br>Made available in DSpace on 2016-04-12T17:59:09Z (GMT). No. of bitstreams: 1 menezes_dc_me_bot.pdf: 1004576 bytes, checksum: ed91db99176a44b0b049ca9ff16a1a70 (MD5) Previous issue date: 2016-03-03<br>Introdução: a presença de dor pós-operatória é uma grande preocupação quando o remifentanil é usado em Anestesia Venosa Total (AVT) devido à meia-vida muito curta desse fármaco e possíveis mecanismos de hiperalgesia e tolerância. Opioides com duração de ação mais prolongada - como sufentanil – têm sido usados durante a indução da AVT com infusão contínua de remifentanil no intuito de suplantar essa limitação. Contudo, a efetividade desta estratégia carece de evidência decorrente de ensaios clínicos. Objetivo: avaliar a eficácia e a segurança da estratégia de administrar sufentanil durante a indução de AVT com remifentanil na analgesia pós-operatória por meio de ensaio clínico randomizado. Método: quarenta pacientes em programação de cirurgia abdominal aberta eletiva foram randomizados para receber infusão contínua de remifentanil em anestesia venosa total, com ou sem a administração de uma dose única de sufentanil, durante a indução da anestesia. Foram avaliados a intensidade da dor pós-operatória, o consumo de morfina e a ocorrência de complicações como náuseas, vômitos, prurido, agitação, sonolência e depressão respiratória, até 48 horas após a cirurgia. O desfecho primário foi o consumo de morfina durante as primeiras 24 horas após a cirurgia. Resultados: a média do consumo de morfina durante as primeiras 24 horas após a cirurgia foi 21,55 mg e 26,68 mg para o grupo que recebeu a dose única de sufentanil e para o grupo controle, respectivamente (p = 0,31). Os pacientes que receberam sufentanil necessitaram de menor quantidade de morfina durante o tempo na Sala de Recuperação Pós-anestésica (SRPA) (média do consumo de morfina total de 7,77 mg versus 15,63 mg, p= 0,02). As diferenças nos escores de dor durante todo o período de estudo e no consumo de morfina após a alta da SRPA não alcançaram significância estatística. A frequência de efeitos adversos não foi estatisticamente diferente entre os grupos. Conclusão: a administração de sufentanil durante a indução anestésica de anestesia venosa total com remifentanil em infusão contínua apresentou superioridade analgésica pós-operatória no período até a alta da SRPA, sem a ocorrência de uma maior proporção de efeitos adversos em relação ao grupo que não recebeu sufentanil.<br>Background: the presence of postoperative pain is a major concern when remifentanil is used for Total Intravenous Anesthesia (TIVA) because of the very short half-life of this medication and possible mechanisms of hyperalgesia and tolerance. Longer acting opioids – such as sufentanil – have been used during induction of remifentanil-based TIVA as a means to overcome this shortcoming. However, the effectiveness of the strategy still lacks evidence from randomized clinical trials. Objective: we conducted a randomized clinical trial to assess the postoperative analgesic efficacy and safety of a single dose of sufentanil administered during the induction of remifentanil-based TIVA. Methods: forty patients scheduled for elective open abdominal surgery were randomized to receive remifentanil-based TIVA with or without the administration of a single dose of sufentanil during anesthesia induction. We assessed postoperative pain intensity, morphine consumption and the occurrence of complications such as nausea, vomiting, pruritus, agitation, somnolence and respiratory depression up to 48 hours after surgery. The primary outcome was morphine consumption during the first 24 hours after surgery. Results: the mean morphine consumption during the first 24 hours after surgery was 21,55 mg and 26,68 mg for the group that received sufentanil and the control group, respectively (P=0,31). Patients in the sufentanil group required less morphine during their time in the Post-Anesthetic Care Unit (PACU) (mean total morphine consumption of 7,77 mg versus 15,63 mg, P=0,02). Differences in pain scores during the whole study period and morphine consumption after discharge from PACU were not statistically significant. The frequency of adverse effects did not statistically vary between the groups. Conclusion: the administration of sufentanil during anesthetic induction of remifentanil-based TIVA continuous infusion showed superior postoperative analgesic efficacy in the period until discharge from PACU and did not increase the incidence of adverse effects.
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Menezes, Daniel Carvalho de. "Utilização do sufentanil durante indução anestésica em anestesia venosa total com remifentanil em infusão contínua." Botucatu, 2016. http://hdl.handle.net/11449/137901.

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Orientador: Fernanda Bono Fukushima<br>Resumo: Introdução: a presença de dor pós-operatória é uma grande preocupação quando o remifentanil é usado em Anestesia Venosa Total (AVT) devido à meia-vida muito curta desse fármaco e possíveis mecanismos de hiperalgesia e tolerância. Opioides com duração de ação mais prolongada - como sufentanil – têm sido usados durante a indução da AVT com infusão contínua de remifentanil no intuito de suplantar essa limitação. Contudo, a efetividade desta estratégia carece de evidência decorrente de ensaios clínicos. Objetivo: avaliar a eficácia e a segurança da estratégia de administrar sufentanil durante a indução de AVT com remifentanil na analgesia pós-operatória por meio de ensaio clínico randomizado. Método: quarenta pacientes em programação de cirurgia abdominal aberta eletiva foram randomizados para receber infusão contínua de remifentanil em anestesia venosa total, com ou sem a administração de uma dose única de sufentanil, durante a indução da anestesia. Foram avaliados a intensidade da dor pós-operatória, o consumo de morfina e a ocorrência de complicações como náuseas, vômitos, prurido, agitação, sonolência e depressão respiratória, até 48 horas após a cirurgia. O desfecho primário foi o consumo de morfina durante as primeiras 24 horas após a cirurgia. Resultados: a média do consumo de morfina durante as primeiras 24 horas após a cirurgia foi 21,55 mg e 26,68 mg para o grupo que recebeu a dose única de sufentanil e para o grupo controle, respectivamente (p = 0,31). Os pacient... (Resumo completo, clicar acesso eletrônico abaixo)<br>Abstract: Background: the presence of postoperative pain is a major concern when remifentanil is used for Total Intravenous Anesthesia (TIVA) because of the very short half-life of this medication and possible mechanisms of hyperalgesia and tolerance. Longer acting opioids – such as sufentanil – have been used during induction of remifentanil-based TIVA as a means to overcome this shortcoming. However, the effectiveness of the strategy still lacks evidence from randomized clinical trials. Objective: we conducted a randomized clinical trial to assess the postoperative analgesic efficacy and safety of a single dose of sufentanil administered during the induction of remifentanil-based TIVA. Methods: forty patients scheduled for elective open abdominal surgery were randomized to receive remifentanil-based TIVA with or without the administration of a single dose of sufentanil during anesthesia induction. We assessed postoperative pain intensity, morphine consumption and the occurrence of complications such as nausea, vomiting, pruritus, agitation, somnolence and respiratory depression up to 48 hours after surgery. The primary outcome was morphine consumption during the first 24 hours after surgery. Results: the mean morphine consumption during the first 24 hours after surgery was 21,55 mg and 26,68 mg for the group that received sufentanil and the control group, respectively (P=0,31). Patients in the sufentanil group required less morphine during their time in the Post-Anesthetic Care... (Complete abstract click electronic access below)<br>Mestre
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Allisson, Anna. "När återhämtar patienten sig snabbast? : Jämförlse mellan inhalationsanestesi och total intravenös anestesi." Thesis, Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-6059.

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Generell anestesi kan ges som inhalationsanestesi eller total intravenös anestesi (TIVA). En förutsägbar anestesi med snabbt uppvaknande och bibehållen vakenhet är en högt önskvärd egenskap oavsett anestesiform. Det råder en klinisk och vetenskaplig diskussion om vilken anestesiform som ger snabbast tidig postoperativ återhämtning. syftet med studien var att jämföra patienters tidiga postoperativa återhämtning efter inhalationsanestesi respektive efter total intravenös anestesi (TIVA). Metoden var en litteraturstudie baserad på 15 vetenskapliga artiklar. Dessa analyserades utifrån frågeställningen: Vilken anestesiform som ger den snabbaste tidiga postoperativa återhämtningen. Det framkom en indelning av resultatet i tre kategorier: snabbare tidig postoperativ återhämtning efter inhalationsanestesi, lika lång tid till återhämtning efter inhalationsanestesi som efter TIVA samt snabbare tidig postoperativ återhämtning efter TIVA. Resultatet visade att inhalationsanestesi gav snabbast tdiig postoperativ återhämtning. Anestesisjuksköterskans handhavande, planering och erfarenhet påverkar patientens uppvakande. därför skulle vidare forskning istället jämföra dessa båda anestesiformer på ett annat sätt. Tiden kunde istället mätas från det att anestesisjukskäterskan extuberat patienten och till payienten verkar adekvat orienterad för att erhålla ett mer jämförbart resultat.<br>General anesthesia includes both inhalations anesthesia and total intravenous anesthesia (TIVA). After any anesthetic technique a de sirable characteristics is a predictably rapid emergence and sustained alertness. There is a clinical and scientific debate about which anesthetic technique who gives the most rapid emergence in the early postoperative recovery. The aim of this study was to compare patients early postoperative recovery after inhalations anesthesia and after total intravenous anesthesia (TIVA). The methods are based on 15 research articles. They where analysized from the questionnaire: which anesthetic technique gives the most rapid emergence in the early postoperative recovery. The results showed that inhalations anesthesia gave the most rapid emergence in the earky postoperative recovery. The nurse anesthetist handling, planning and experience affect the patients awakening. Therefore further research instead could compare these anesthetic techniques in another way. The time after the nurse anesthetist has extubate the patient until the patient is adequate orientated, could be measured to find a more comparable result.
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Batista, Priscila Andrea Costa dos Santos [UNESP]. "Estudo comparativo entre as ventilações espontânea, mandatória intermitente sincronizada, pressão de suporte e volume garantido e suporte pressórico, em coelhos anestesiados com propofol e induzidos à hipovolemia aguda." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/101147.

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Made available in DSpace on 2014-06-11T19:31:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-06-20Bitstream added on 2014-06-13T20:41:26Z : No. of bitstreams: 1 batista_pacs_dr_jabo.pdf: 1010587 bytes, checksum: 02a7bf064302a3fb5658ae96cde626bf (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Avaliaram-se os efeitos das ventilações espontânea, mandatória intermitente sincronizada (SIMV), pressão de suporte e volume garantido (VAPSV) e suporte pressórico (VPS) sobre as variáveis hemogasométricas, cardiovasculares e da dinâmica respiratória em coelhos anestesiados com infusão contínua de propofol e submetidos à hipovolemia aguda. Para tal, foram utilizados 40 coelhos, da raça Nova Zelândia, os quais foram distribuídos em quatro grupos, sendo denominados GE (ventilação espontânea), GM (SIMV), GP (VPS) e GV (VAPSV). Na medicação préanestésica foi administrado cetamina (15 mg/kg) e xilazina (1 mg/kg) pela via intramuscular. O propofol foi empregado na indução (8mg/kg) e na manutenção anestésica (0,5 mg/kg/min). Decorridos 40 minutos da indução, os animais foram induzidos à hipovolemia por meio da retirada de sangue arterial (12 mL/kg). Os parâmetros foram mensurados 40 minutos após a indução anestésica (M0), seguido de novas mensurações a cada dez minutos depois da hipovolemia (de M1a M6). O método estatístico utilizado foi o quadrado mínimo, utilizando o programa computacional SAS. Em relação às variáveis cardiovasculares, as médias de débito cardíaco no GE, GP e GM foram maiores que as no GV. Quanto à hemogasometria, a pressão parcial de oxigênio no sangue arterial (PaO2) foi maior no GV do que no GE e GP. Em relação às variáveis respiratórias, os valores da pressão alveolar de oxigênio (PAO2), diferença alvéolo-arterial de oxigênio (AaDO2), espaço morto fisiológico (Vdfis) e espaço morto alveolar (Vdalv) no GE foram maiores do que no GM e GV . Enquanto, as médias do conteúdo arterial de oxigênio (CaO2), diferença entre a tensão de o dióxido de carbono alveolar e o expirado [P(a-ET)CO2], volume corrente (Vt) e tempo inspiratório (Tinsp), no GE foram menores do que no ao GV e GM...<br>The effects of spontaneous ventilation, pressure support ventilation (VPS), synchronized intermittent mandatory ventilation (SIMV) and ventilation with pressure support and volume assured (VAPSV) on cardiovascular, blood-gas and respiratory dynamic variables, in rabbits anesthetized with continuous infusion of propofol and underwent acute hypovolemia, were evaluated. Forty New Zealand rabbits were randomly assigned into four groups, namely: GE (spontaneous ventilation), GM (SIMV), GP (VPS) and GV (VAPSV). In premedication were administered ketamine (15 mg/kg) and xylazine (1 mg/kg) intramuscularly. Propofol was used in induction (8 mg/kg) and anesthesia maintenance (0.5 mg/kg/min). After 40 minutes, the rabbits were induced to hypovolemia by withdrawing arterial blood (12 ml/kg). The parameters were measured 40 minutes after anesthetic induction (M0) and, then at 10-minute intervals after hipovolemia induction (from M1 to M6). Numeric data were submitted to the least-squares using the SAS program. In the hemodynamic parameters, means of cardiac output in GP, GE and GM were higher than in GV. About blood-gas parameters, arterial partial pressure of oxygen (PaO2) was bigger in GV than in GE and GP. The arterial hemoglobin saturation (SaO2) was lower in GP than in GV. Regarding respiratory variables, the values of alveolar oxygen partial pressure (PAO2), alveolar-arterial oxygen gradient (AaDO2), physiological dead space (Vdfis), and alveolar dead space (Vdalv) in GE were bigger than in GM, GV and GP. While, means of arterial oxygen content (CaO2), alveolar-arterial carbon dioxide gradient [P(a-ET)CO2], tidal volume (Vt) and inspiratory time (Tinsp), in GE were lower than in GV,GM and GP. The peak inspiratory pressure (PIP) was higher compared to the GV and GM, work of breathing was higher compared to the GV to GV ... (Complete abstract click electronic access below)
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6

Costa, Paula Ferreira da [UNESP]. "Parâmetros ventilométricos, cardiovasculares, hematológicos e índice biespectral, em cães anestesiados com infusão contínua de propofol, associado ou não ao tramadol." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/89039.

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Made available in DSpace on 2014-06-11T19:23:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-02Bitstream added on 2014-06-13T19:50:47Z : No. of bitstreams: 1 costa_pf_me_jabo.pdf: 620381 bytes, checksum: 87c337a2a755bf1ab30092e7a26ca60f (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Avaliaram-se os efeitos da anestesia total intravenosa com propofol associado ou não ao tramadol sobre os parâmetros ventilométricos, cardiovasculares, hematológicos e índice biespectral em cães. Utilizaram-se oito animais submetidos a duas anestesias com 15 dias de intervalo, formando-se dois grupos (n=8): grupo controle (GC) e grupo tramadol (GT). Os animais foram induzidos à anestesia geral com propofol (10mg/kg) por via intravenosa. Seguindose, iniciou-se a infusão do fármaco na taxa de 0,7 mg/kg/min. Os cães foram mantidos em ventilação controlada a pressão de maneira a obter-se normocapnia, com FiO2=0,6. No GT os animais receberam, por via intravenosa, tramadol (2 mg/kg), seguido de infusão contínua do fármaco na taxa de 0,5 mg/kg/h, enquanto no GC, foi administrada solução de NaCl a 0,9%, seguido de infusão contínua da mesma solução, em volume idêntico ao empregado no GT. As mensurações das variáveis, exceto as hematológicas, iniciaram-se 30 minutos após o bolus de propofol (M0), e então em intervalos de 15 minutos, durante um período de 60 minutos (M15, M30, M45 e M60). Para os parâmetros hematológicos, uma amostra de sangue foi coletada antes da indução anestésica (Mbasal), 30 minutos após a indução (M0) e em intervalos de 30 minutos durante 60 minutos (M30 e M60). O método estatístico utilizado foi a Análise de Perfil (P<0,05). A associação de propofol e tramadol não promoveu alterações nos parâmetros ventilométricos, cardiovasculares e eletrocardiográficos avaliados e no índice biespectral, mas promoveu diminuição da temperatura corpórea (TC), redução da contagem de hemácias (He), hemoglobina (Hb) e hematócrito (Ht). O sinergismo do tramadol com propofol também reduziu as contagens de leucócitos totais (Le) e linfócitos (Linf).<br>The effects of total intravenous anesthesia with propofol associated or not to tramadol on ventilometric, cardiovascular, hematologic and bispectral index parameters in dogs were evaluated. Eight adult mongrel dogs were anesthetized on 2 occasions, 15 d apart, in a randomized crossover fashion. Two groups were formed: control group (GC) and tramadol group (GT). Propofol was used for induction (10 mg/kg IV) followed by a continuous rate infusion at 0.7 mg/kg/min. The animals were kept in pressure controlled ventilation with FiO2=0.6 with the aim to produce normocapnia. In GT, the tramadol bolus (2 mg/kg) followed by a continuous rate infusion at 0.5 mg/kg/min was administered in dogs via intravenous route. While, in GC, the NaCl to 0.9% was administrated followed by its continuous rate infusion, in the same volume that was used in GT. The measurement of all variables, except the hematologic parameters, was performed 30 minutes after propofol bolus (M0), and then, in intervals of 15 minutes, during 60 minutes (M15, M30, M45 and M60). For hematologic parameters, a blood sample was collected before anesthesia induction (Mbasal), 30 minutes after induction (M0) and, then, in intervals of 30 minutes during 60 minutes (M30 and M60). Numeric data were submitted to Profile analysis (P<0,05). The association of propofol and tramadol did not promote changes in bispectral index, ventilometric, cardiovascular and electrocardiographic parameters, but it promoted corporal temperature (TC) decrease and reduction in counting of hemaceas (He), hemoglobin (Hb) and hematocrit (Ht). The synergism of tramadol with propofol reduced the counting of total leukocytes (Le) and lymphocytes (Lymph).
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Batista, Priscila Andrea Costa dos Santos. "Estudo comparativo entre as ventilações espontânea, mandatória intermitente sincronizada, pressão de suporte e volume garantido e suporte pressórico, em coelhos anestesiados com propofol e induzidos à hipovolemia aguda /." Jaboticabal : [s.n.], 2011. http://hdl.handle.net/11449/101147.

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Orientador: Newton Nunes<br>Banca: João Moreira da Costa Neto<br>Banca: José Antonio Marques<br>Banca: Paulo Sérgio Patto dos Santos<br>Banca: Roberta Carareto<br>Resumo: Avaliaram-se os efeitos das ventilações espontânea, mandatória intermitente sincronizada (SIMV), pressão de suporte e volume garantido (VAPSV) e suporte pressórico (VPS) sobre as variáveis hemogasométricas, cardiovasculares e da dinâmica respiratória em coelhos anestesiados com infusão contínua de propofol e submetidos à hipovolemia aguda. Para tal, foram utilizados 40 coelhos, da raça Nova Zelândia, os quais foram distribuídos em quatro grupos, sendo denominados GE (ventilação espontânea), GM (SIMV), GP (VPS) e GV (VAPSV). Na medicação préanestésica foi administrado cetamina (15 mg/kg) e xilazina (1 mg/kg) pela via intramuscular. O propofol foi empregado na indução (8mg/kg) e na manutenção anestésica (0,5 mg/kg/min). Decorridos 40 minutos da indução, os animais foram induzidos à hipovolemia por meio da retirada de sangue arterial (12 mL/kg). Os parâmetros foram mensurados 40 minutos após a indução anestésica (M0), seguido de novas mensurações a cada dez minutos depois da hipovolemia (de M1a M6). O método estatístico utilizado foi o quadrado mínimo, utilizando o programa computacional SAS. Em relação às variáveis cardiovasculares, as médias de débito cardíaco no GE, GP e GM foram maiores que as no GV. Quanto à hemogasometria, a pressão parcial de oxigênio no sangue arterial (PaO2) foi maior no GV do que no GE e GP. Em relação às variáveis respiratórias, os valores da pressão alveolar de oxigênio (PAO2), diferença alvéolo-arterial de oxigênio (AaDO2), espaço morto fisiológico (Vdfis) e espaço morto alveolar (Vdalv) no GE foram maiores do que no GM e GV . Enquanto, as médias do conteúdo arterial de oxigênio (CaO2), diferença entre a tensão de o dióxido de carbono alveolar e o expirado [P(a-ET)CO2], volume corrente (Vt) e tempo inspiratório (Tinsp), no GE foram menores do que no ao GV e GM ... (Resumo completo, clicar acesso eletrônico abaixo)<br>Abstract: The effects of spontaneous ventilation, pressure support ventilation (VPS), synchronized intermittent mandatory ventilation (SIMV) and ventilation with pressure support and volume assured (VAPSV) on cardiovascular, blood-gas and respiratory dynamic variables, in rabbits anesthetized with continuous infusion of propofol and underwent acute hypovolemia, were evaluated. Forty New Zealand rabbits were randomly assigned into four groups, namely: GE (spontaneous ventilation), GM (SIMV), GP (VPS) and GV (VAPSV). In premedication were administered ketamine (15 mg/kg) and xylazine (1 mg/kg) intramuscularly. Propofol was used in induction (8 mg/kg) and anesthesia maintenance (0.5 mg/kg/min). After 40 minutes, the rabbits were induced to hypovolemia by withdrawing arterial blood (12 ml/kg). The parameters were measured 40 minutes after anesthetic induction (M0) and, then at 10-minute intervals after hipovolemia induction (from M1 to M6). Numeric data were submitted to the least-squares using the SAS program. In the hemodynamic parameters, means of cardiac output in GP, GE and GM were higher than in GV. About blood-gas parameters, arterial partial pressure of oxygen (PaO2) was bigger in GV than in GE and GP. The arterial hemoglobin saturation (SaO2) was lower in GP than in GV. Regarding respiratory variables, the values of alveolar oxygen partial pressure (PAO2), alveolar-arterial oxygen gradient (AaDO2), physiological dead space (Vdfis), and alveolar dead space (Vdalv) in GE were bigger than in GM, GV and GP. While, means of arterial oxygen content (CaO2), alveolar-arterial carbon dioxide gradient [P(a-ET)CO2], tidal volume (Vt) and inspiratory time (Tinsp), in GE were lower than in GV,GM and GP. The peak inspiratory pressure (PIP) was higher compared to the GV and GM, work of breathing was higher compared to the GV to GV ... (Complete abstract click electronic access below)<br>Doutor
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Barbosa, Vivian Fernanda. "Avaliação de diferentes frações inspiradas de oxigênio em coelhos submetidos ao pneumoperitônio e mantidos em cefalodeclive /." Jaboticabal : [s.n.], 2011. http://hdl.handle.net/11449/101117.

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Orientador: Newton Nunes<br>Banca: José Antonio Marques<br>Banca: Paulo Sérgio Patto dos Santos<br>Banca: João Moreira da Costa Neto<br>Banca: Roberta Carareto<br>Resumo: Avaliaram-se os efeitos respiratórios, hemogasométricos e cardiovasculares do fornecimento de diferentes frações inspiradas de oxigênio (FiO2) em coelhos submetidos ao pneumoperitônio e mantidos em cefalodeclive ("Trendelenburg a 30°). Foram utilizados oito coelhos adultos em cada grupo, os quais foram pré-medicados com acepromazina (0,5 mg/kg) e submetidos a anestesia com propofol (10 mg/kg, seguido de infusão contínua de 1,2 mg/kg/min) e rocurônio (0,6 mg/kg bolus e infusão contínua de 0,6 mg/kg/h), sendo que, cada procedimento anestésico foi diferenciados pela FiO2 fornecida ao paciente, permitindo formar os seguintes grupos: G40 (FiO2 = 0,4), G60 (FiO2 = 0,6) e G100 (FiO2 = 1,0). Os parâmetros foram mensurados uma hora após a indução anestésica (M0) e a cada 20 minutos, durante um período de 100 minutos (M20 a M100). Os animais foram mantidos em ventilação controlada a tempo, e receberam PEEP de 2 cmH2O em M80 e M100. Os dados foram submetidos à Análise de Perfil (p<0,05). A comparação das diferentes frações inspiradas foi caracterizada por aumento da PAO2, PaO2, PvO2 e AaDO2 e redução da relação PaO2/FiO2 quanto mais altas foram as FiO2. Nos grupos tratados com maiores e menores frações inspiradas constatou-se alteração da SaO2, PvCO2 e SvO2 . Conclui-se que as diferentes FiO2 não alteram as variáveis hemodinâmicas e que o fornecimento de oxigênio a 40% é o mais indicado por melhor manter as trocas gasosas e a estabilidade dos parâmetros ventilatórios. A inclusão de PEEP promoveu discretas alterações hemodinâmicas e ventilatórias, e quando associada a elevadas FiO2, resultou em incremento da oxigenação arterial e prejuízos na eliminação de dióxido de carbono<br>Abstract: The effects of several inspired oxygen fractions (FiO2) on the blood gases, respiratory and cardiovascular parameters were evaluated in rabbits undergoing pneumoperitoneum under head-down tilt position ("Trendelenburg" position at 30°). Eight adult rabbits were used in each group. The animals were premedicated with acepromazine (0.5 mg/kg) and, thereafter underwent general anesthesia with propofol (10 mg//kg, followed by continuous infusion of 1.2 mg/kg/min) and rocuronium (0.6 mg/kg, followed by continuous infusion of 0.6 mg/kg/h). The patients were distributed into three groups according to the FiO2 regimen during general anesthesia: G40 (FiO2 = 0,4), G60 (FiO2 = 0,6) and G100 (FiO2 = 1,0). The first data sampling (M0) was carried out one hour after anesthesia induction (M0). Additional recordings were performed every 20-minute intervals for 100 minutes (M20 to M100). The animals were maintained in time controlled ventilation. Additionally, PEEP (2 cmH2O) was performed in M80 and M100. Numeric data were submitted to Profile Analysis (p<0.05). The comparison among the different FiO2 regimen was based on the variation of the values of PAO2, PaO2, PvO2 and AaDO2, which increased in patients submitted to higher FiO2 regimen. Significant changes in SaO2, PvCO2 e SvO2 were documented in the patients belonging to the groups that underwent higher and lower FiO2. Results showed that FiO2 does not impair hemodynamic parameters and 40% oxygen is the most suitable for better maintenance of gas exchange and stability of ventilatory parameters. The PEEP inclusion promoted discrete hemodynamic and ventilatory changes and when combined with high FiO2 it resulted in increased blood oxygenation and damage on the elimination of carbon dioxide<br>Doutor
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Lopes, Patrícia Cristina Ferro [UNESP]. "Infusão contínua de propofol ou tiopental em cães portadores de hipertensão pulmonar induzida pela serotonina." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/101115.

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Made available in DSpace on 2014-06-11T19:31:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-18Bitstream added on 2014-06-13T19:20:10Z : No. of bitstreams: 1 lopes_pcf_dr_jabo.pdf: 913328 bytes, checksum: efbc4209053a9d5baf857b73e739ed21 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Avaliaram-se os efeitos da infusão contínua de propofol ou tiopental sobre os parâmetros respiratórios, hemodinâmicos, hemogasométricos e do índice biespectral em cães portadores de hipertensão pulmonar (HP) induzida pela serotonina (5-HT). Utilizaram-se 20 cães adultos SRD, machos ou fêmeas, distribuídos em dois grupos de dez animais denominados grupo propofol (GP, n= 10) e grupo tiopental (GT, n = 10). O peso médio dos cães no GP foi 11,8 ± 1,8 kg e no GT 10,6 ± 2,7 kg. O propofol foi empregado na indução (8 ± 0,03 mg/kg) e manutenção da anestesia (0,8 mg/kg/min) no GP, e o tiopental foi utilizado para indução (22 ± 2,92 mg/kg) seguido por infusão contínua (0,5 mg/kg/min) no GT. Em seguida, a ventilação mecânica ciclada a tempo foi iniciada. A HP foi induzida pela administração de 5-HT em bolus (10 μg/kg) seguido por infusão contínua (1 mg/kg/h) na artéria pulmonar. As mensurações dos parâmetros tiveram início antes da aplicação (M0) e após 30 minutos da administração da 5-HT (M30), seguida de intervalos de 15 minutos (M45, M60, M75 e M90). As variáveis foram submetidas à Análise de Perfil (p<0,05). O coeficiente de Pearson foi calculado em ambos os grupos para determinar a correlação entre mistura arteriovenosa (Qs/Qt) e diferença de tensão entre o oxigênio alveolar e o arterial (AaDO2), entre Qs/Qt e o índice respiratório (IR), entre Qs/Qt e a relação artérioalveolar (a/A) e entre Qs/Qt e o índice de oxigenção (IO). Os resultados mostraram que a indução da HP alterou as variáveis hemogasométricas, respiratórias, a frequência cardíaca (FC), sendo registradas diferenças significativas entre os grupos...<br>The effects of continuous infusion of propofol or thiopental on respiratory, hemodynamic, blood-gas parameters and on bispectral index, in dogs induced to pulmonary hypertension (PH) by serononin (5-HT), were evaluated. Twenty adult mongrel dogs, male or female, were randomly assigned into two groups composed by ten animals: propofol group (PG, n = 10) and thiopental group (TG, n= 10). In PG, dogs weighing 11.8 ± 1.8 kg and in TG, 10.6 ± 2.7 kg. Propofol was used for induction (8 ± 0.03 mg/kg) and maintenance of anesthesia (0.8 mg/kg/minute) in PG. Thiopental was used for induction (22 ± 2.92 mg/kg) followed by continuous infusion (0.5 mg/kg/minute) in TG. Mechanical ventilation using time cycled was started. PH was induced by administration of a serotonin (5-HT) bolus (10 μg/kg) followed by continuous infusion (1 mg/kg/hour) in the pulmonary artery. The parameters were measured before administration of 5-HT (T0), after 30 minutes (T30) and, then, at 15-minute intervals (T45, T60, T75 and T90). Numeric data were submitted to Profile analysis (P<0.05). Pearson’s coefficient was calculated in both groups to determine the correlation between venous admixture (Qs/Qt) and alveolar-arterial oxygen tension difference (AaDO2), between Qs/Qt and respiratory index (RI), between Qs/Qt and alveolo-arterial ratio (a/A) and between Qs/Qt and oxygenation index (IO) ... (Complete abstract click electronic access below)
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10

Barbosa, Vivian Fernanda [UNESP]. "Avaliação de diferentes frações inspiradas de oxigênio em coelhos submetidos ao pneumoperitônio e mantidos em cefalodeclive." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/101117.

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Made available in DSpace on 2014-06-11T19:31:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-06-21Bitstream added on 2014-06-13T19:01:28Z : No. of bitstreams: 1 barbosa_vf_dr_jabo.pdf: 857896 bytes, checksum: be55354f43cf593758c89ed8d7f0452f (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Avaliaram-se os efeitos respiratórios, hemogasométricos e cardiovasculares do fornecimento de diferentes frações inspiradas de oxigênio (FiO2) em coelhos submetidos ao pneumoperitônio e mantidos em cefalodeclive (“Trendelenburg a 30°). Foram utilizados oito coelhos adultos em cada grupo, os quais foram pré-medicados com acepromazina (0,5 mg/kg) e submetidos a anestesia com propofol (10 mg/kg, seguido de infusão contínua de 1,2 mg/kg/min) e rocurônio (0,6 mg/kg bolus e infusão contínua de 0,6 mg/kg/h), sendo que, cada procedimento anestésico foi diferenciados pela FiO2 fornecida ao paciente, permitindo formar os seguintes grupos: G40 (FiO2 = 0,4), G60 (FiO2 = 0,6) e G100 (FiO2 = 1,0). Os parâmetros foram mensurados uma hora após a indução anestésica (M0) e a cada 20 minutos, durante um período de 100 minutos (M20 a M100). Os animais foram mantidos em ventilação controlada a tempo, e receberam PEEP de 2 cmH2O em M80 e M100. Os dados foram submetidos à Análise de Perfil (p<0,05). A comparação das diferentes frações inspiradas foi caracterizada por aumento da PAO2, PaO2, PvO2 e AaDO2 e redução da relação PaO2/FiO2 quanto mais altas foram as FiO2. Nos grupos tratados com maiores e menores frações inspiradas constatou-se alteração da SaO2, PvCO2 e SvO2 . Conclui-se que as diferentes FiO2 não alteram as variáveis hemodinâmicas e que o fornecimento de oxigênio a 40% é o mais indicado por melhor manter as trocas gasosas e a estabilidade dos parâmetros ventilatórios. A inclusão de PEEP promoveu discretas alterações hemodinâmicas e ventilatórias, e quando associada a elevadas FiO2, resultou em incremento da oxigenação arterial e prejuízos na eliminação de dióxido de carbono<br>The effects of several inspired oxygen fractions (FiO2) on the blood gases, respiratory and cardiovascular parameters were evaluated in rabbits undergoing pneumoperitoneum under head-down tilt position (“Trendelenburg” position at 30°). Eight adult rabbits were used in each group. The animals were premedicated with acepromazine (0.5 mg/kg) and, thereafter underwent general anesthesia with propofol (10 mg//kg, followed by continuous infusion of 1.2 mg/kg/min) and rocuronium (0.6 mg/kg, followed by continuous infusion of 0.6 mg/kg/h). The patients were distributed into three groups according to the FiO2 regimen during general anesthesia: G40 (FiO2 = 0,4), G60 (FiO2 = 0,6) and G100 (FiO2 = 1,0). The first data sampling (M0) was carried out one hour after anesthesia induction (M0). Additional recordings were performed every 20-minute intervals for 100 minutes (M20 to M100). The animals were maintained in time controlled ventilation. Additionally, PEEP (2 cmH2O) was performed in M80 and M100. Numeric data were submitted to Profile Analysis (p<0.05). The comparison among the different FiO2 regimen was based on the variation of the values of PAO2, PaO2, PvO2 and AaDO2, which increased in patients submitted to higher FiO2 regimen. Significant changes in SaO2, PvCO2 e SvO2 were documented in the patients belonging to the groups that underwent higher and lower FiO2. Results showed that FiO2 does not impair hemodynamic parameters and 40% oxygen is the most suitable for better maintenance of gas exchange and stability of ventilatory parameters. The PEEP inclusion promoted discrete hemodynamic and ventilatory changes and when combined with high FiO2 it resulted in increased blood oxygenation and damage on the elimination of carbon dioxide
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Books on the topic "Total Intravenous Anesthesia (TIVA)"

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Absalom, Anthony R., and Keira P. Mason, eds. Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4.

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Total Intravenous Anaesthesia. Butterworth-Heinemann, 2000.

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B, Kay, ed. Total intravenous anaesthesia. Elsevier, 1991.

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Mason, Keira P., and Anthony R. Absalom. Total Intravenous Anesthesia and Target Controlled Infusions: A Comprehensive Global Anthology. Springer, 2018.

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Nizamuddin, Sarah, and Caitlin Aveyard. Airway Foreign Body Aspiration. Edited by Kirk Lalwani, Ira Todd Cohen, Ellen Y. Choi, and Vidya T. Raman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190685157.003.0024.

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Aspiration of a foreign body is a potentially life-threatening problem that often necessitates an anesthetic for removal of the foreign body. Foreign body aspiration is most common among children aged 1 to 4 years old and has a wide variety of symptoms ranging from a mild, nagging cough to complete airway obstruction. Definitive diagnosis and treatment of foreign body aspiration involve flexible or rigid bronchoscopy. The urgency of the procedure depends on the type of object aspirated and the location of the foreign body in the airway. The appropriate anesthetic for removal of the foreign body is dependent upon the surgeon’s plan and involves several steps in decision-making: intravenous versus inhalational induction, airway maintenance (endotracheal tube vs. supraglottic airway vs. mask), spontaneous versus controlled ventilation, maintenance of anesthesia (total intravenous anesthesia vs. volatile agents). Good communication with the surgeon or proceduralist is key to a safe and effective anesthetic.
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Chidambaran, Vidya, and Senthilkumar Sadhasivam. Foreign Body in the Airway. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0012.

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Anesthetic management of suspected foreign body aspiration in the airway can be challenging. It is critical to develop a coordinated plan with the surgeon. Removal of a foreign body may necessitate laryngoscopy, bronchoscopy (commonly used), thoracoscopy, thoracotomy, or even a tracheotomy. Anesthesia could be induced using inhalation or intravenous anesthetics, while maintaining spontaneous ventilation. However, there is no consensus as to whether controlled or spontaneous ventilation is more advantageous. Maintaining deep planes of anesthesia, with minimal airway reflexes, during bronchoscopy is essential. In the event that total airway obstruction due to a tracheal foreign body occurs, a potentially life-saving technique is to push the object deeper into one of the main bronchi, for temporary relief. Postoperatively, steroids, racemic epinephrine, and intubation/ventilation may be necessary for airway edema. A chest x-ray may be indicated to rule out postobstructive pulmonary edema, pneumothorax, and pneumonia.
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Book chapters on the topic "Total Intravenous Anesthesia (TIVA)"

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Kennedy, Martin J. "Total Intravenous Anesthesia (TIVA)." In Questions and Answers in Small Animal Anesthesia. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118912997.ch14.

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Montgomery, Jane, and Mary Stocker. "Economics of TIVA." In Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4_33.

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Schraag, Stefan. "TIVA for Cardiac Surgery." In Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4_30.

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Glass, Peter S. A. "The Principles of Total Intravenous Anesthesia (TIVA)." In Anesthesia for the New Millennium. Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4566-4_14.

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Sutcliffe, Nicholas. "TCI/TIVA Adult Case Studies." In Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4_23.

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Beths, Thierry. "TIVA/TCI in Veterinary Practice." In Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4_31.

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Leslie, Kate. "Awareness and Dreaming During TIVA." In Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4_44.

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Yuen, Vivian Man-ying. "Pediatric TIVA/TCI: Case Presentations and Discussion." In Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4_22.

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Johnson, Ken B. "Advantages, Disadvantages, and Risks of TIVA/TCI." In Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4_32.

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Lamperti, Massimo, and Fazil Ashiq. "TCI and TIVA for Neurosurgery: Considerations and Techniques." In Total Intravenous Anesthesia and Target Controlled Infusions. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47609-4_28.

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Conference papers on the topic "Total Intravenous Anesthesia (TIVA)"

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Kumar, Jonnakuti S., Gandhi K. Anil, Nidhi B. Panda, Apinderpreet Singh, and Divya Jain. "Comparison of Total Intravenous Anesthesia (TIVA) versus Volatile Induction Maintenance Anesthesia (VIMA) Complemented by Controlled Hypotension on Quality of Surgical Field during Transsphenoidal Resection of Pituitary Tumor." In Abstracts of 21st Annual Conference of the Indian Society of Neuroanaesthesiology and Critical Care (ISNACC 2020). Thieme Medical and Scientific Publishers Private Ltd., 2020. http://dx.doi.org/10.1055/s-0040-1709574.

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Singh, M., R. Chandrashekar, and I. Khan. "ESRA19-0120 Intraoperative use of depth of anaesthesia (DOA) monitoring in total intravenous anaesthesia (TIVA) with neuromuscular blockade: an audit in UK district general hospital." In Abstracts of the European Society of Regional Anesthesia, September 11–14, 2019. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/rapm-2019-esraabs2019.306.

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Paz, Luis A., Margarida M. Silva, Simao Esteves, Rui Rabico, and Teresa Mendonca. "Automated total intravenous anesthesia (amTIVA) from induction to recovery." In 2014 IEEE International Symposium on Medical Measurements and Applications (MeMeA). IEEE, 2014. http://dx.doi.org/10.1109/memea.2014.6860039.

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Zeiner, S., O. Kimberger, K. Thüringer, O. Zotti, and E. Knolle. "Schmerzmedizin (D) – Intravenous diclofenac-orphenadrine in the treatment of postoperative pain after remifentanil-based total intravenous anesthesia for elective cruciate ligament surgery." In AIC 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1700689.

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Reports on the topic "Total Intravenous Anesthesia (TIVA)"

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Murray, W. B. Provider Needs for Distributed Simulation Education System in Total Intravenous Anesthesia and Target Controlled Infusion. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada542258.

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Murray, W. B. Provider Needs for Distributed Simulation Education System in Total Intravenous Anesthesia and Target Controlled Infusion. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada542263.

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Acred, Aleksander, Milena Devineni, and Lindsey Blake. Opioid Free Anesthesia to Prevent Post Operative Nausea/Vomiting. University of Tennessee Health Science Center, 2021. http://dx.doi.org/10.21007/con.dnp.2021.0006.

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Purpose The purpose of this study is to compare the incidence of post-operative nausea and vomiting (PONV) in opioid-utilizing and opioid-free general anesthesia. Background PONV is an extremely common, potentially dangerous side effect of general anesthesia. PONV is caused by a collection of anesthetic and surgical interventions. Current practice to prevent PONV is to use 1-2 antiemetics during surgery, identify high risk patients and utilize tracheal intubation over laryngeal airways when indicated. Current research suggests minimizing the use of volatile anesthetics and opioids can reduce the incidence of PONV, but this does not reflect current practice. Methods In this scoping review, the MeSH search terms used to collect data were “anesthesia”, “postoperative nausea and vomiting”, “morbidity”, “retrospective studies”, “anesthesia, general”, “analgesics, opioid”, “pain postoperative”, “pain management” and “anesthesia, intravenous”. The Discovery Search engine, AccessMedicine and UpToDate were the search engines used to research this data. Filters were applied to these searches to ensure all the literature was peer-reviewed, full-text and preferably from academic journals. Results Opioid free anesthesia was found to decrease PONV by 69%. PONV incidence was overwhelming decreased with opioid free anesthesia in every study that was reviewed. Implications The future direction of opioid-free anesthesia and PONV prevention are broad topics to discuss, due to the nature of anesthesia. Administration of TIVA, esmolol and ketamine, as well as the decision to withhold opioids, are solely up to the anesthesia provider’s discretion. Increasing research and education in the importance of opioid-free anesthesia to decrease the incidence of PONV will be necessary to ensure anesthesia providers choose this protocol in their practice.
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