Dissertations / Theses on the topic 'TotalPSA'
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Hoberg, Emilia. "Metodverifiering av reagens med förhöjt tröskelvärde för biotininterferens för biomarkörerna NT-proBNP, prokalcitonin och prostataspecifikt antigen på Roche Cobas® e801." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-96861.
Full textBiotin is naturally found in foods, and we obtain this vitamin through our daily diet. Biotin supplements as well as high doses of biotin in drugs can lead to biotin interference in clinical immunochemical analyzes. Therefore, the purpose of this study was to methodically verify four new reagents from Roche Diagnostics® with a higher threshold for biotin interference, used in the diagnosis and treatment of heart faliure, sepsis and prostate cancer. The four reagents, Elecsys® proBNP II, Elecsys® BRAHMS PCT, Elecsys® total PSA and Elecsys® free PSA were method-verified for use on Cobas® e801. The study material consisted of 20 patient samples of lithium heparin plasma per reagent. In total 80 samples were analyzed.The result of the verification of Elecsys® proBNP II showed a correlation to the existing reagent of r = 0.9998 and Bland-Altman analysis showed a distribution of the results of <10 %. The withinseries precision study yielded CV 1.56 %. Elecsys® BRAHMS PCT had a correlation of r = 0.9997 and the Bland-Altman analysis showed a distribution of > 10 %. The withinseries precision study gave CV 1.70 %. For Elecsys® total PSA and free PSA, the correlation to the existing reagent was r = 1 and 0.9997, respectively, and the Bland-Altman analysis showed a distribution of <10 % in both reagents. The withinseries precision study yielded CV 0.44 % and CV 2.67 % respectively.The results for all reagents show a good correlation to the existing reagent and a high accuracy of measurement, which indicates that the four new reagents can be used.
Kloudová, Erika. "Totalita LARPu." Master's thesis, Vysoké učení technické v Brně. Fakulta výtvarných umění, 2019. http://www.nusl.cz/ntk/nusl-396116.
Full textNavarro, Veronica, Harumi Oshiro, Bruce Peña, and Pineda Fernando Moquillaza. "Situs inversus totalis." Sociedad de Gastroenterología del Perú, 2014. http://hdl.handle.net/10757/322409.
Full textRevisión por pares
Daugan, Alain. "Synthèses totales de lignanes optiquement actifs." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376042586.
Full textDaugan, Alain. "Synthèses totales de lignanes optiquement actifs." Paris 11, 1987. http://www.theses.fr/1987PA112225.
Full text(R)-(+)-β-Benzyl-γ-butyrolactones are key-intermediates in the total syntheses of natural lignans and analogues. The only optically active lactone of this type, which was known before us, is (R)-(+)-β piperonyl-γ -butyrolactone, two syntheses of which have been described in the literature. Both these syntheses being long and consequently of limited preparative value, we sought to develop a simpler and more efficient route leading to optically active β-benzyl-γ-butyrolactones. Thus, the methyl (R,S)-α-benzylhemisuccinate resulting from a STOBBE condensation with an appropriate aromatic aldehyde, followed by catalytic hydrogenation of the intermediate α-benzylidene hemisuccinic ester, was resolved by means of a chiral base. Reduction of each enantiomer, using calcium borohydride, then led to the corresponding optically active β-benzyl-γ-butyrolactone. In this way, we obtained the following three lactones in both (R)-(+) and (S)-(-) enantiomeric forms, β-piperonyl-, β-veratryl-, and β-vanillyl-γ-butyrolactones. We used these chiral precursors to synthesize various lignoids including fifteen natural lignans
BAUDER, CLAUDE. "Syntheses totales de porphyrines d'interet geochimique." Université Louis Pasteur (Strasbourg) (1971-2008), 1990. http://www.theses.fr/1990STR13211.
Full textLegault, Benoît. "Derivations partielles et totales du coeur droit." Clermont-Ferrand 1, 1994. http://www.theses.fr/1994CLF1MS08.
Full textSandri, Jacqueline. "Synthèses totales de l'EPA et du DHA." Aix-Marseille 3, 1994. http://www.theses.fr/1994AIX30032.
Full textTorre, Aurélien de la. "Synthèses totales de neurofuranes et dihomo-isofuranes." Thesis, Montpellier 1, 2014. http://www.theses.fr/2014MON13513/document.
Full textArachidonic acid (AA, C20 :4, n-6) and docosahexaenoïc acid (DHA, C22 :6, n-3) are phospholipidic membranes polyinsaturated fatty acids. During and oxidative stress, these are metabolized into tetrahydrofuran-containing compounds, known as isofurans (IsoFs) for AA and neurofurans (NeuroFs) for DHA. We were interested in the total synthesis of these compounds in the aim of getting access to novel biomarkers of the oxidative stress. Towards the same goal, we envisaged the total synthesis of potential analog structures coming from adrenic acid (AdA, C22 :4, n-6), that we named dihomo-isofurans (dihomo-IsoFs)
Frioux, Renaud Letenneur Joseph. "Suivi d'une série de 106 prothèses totales de genou à glissement de type GENESIS II sur un recul de 3 à 5 ans." [S.l.] : [s.n.], 2005. http://theses.univ-nantes.fr/thesemed/SPEfrioux.pdf.
Full textPacheco, Eslava Angélica. "PREVALENCIA DE COLESTASIS INTRAHEPÁTICA GESTACIONAL EN EL HOSPITAL SANTA ROSA, DURANTE EL PERIODO 2013-2015." Bachelor's thesis, Universidad Ricardo Palma, 2016. http://cybertesis.urp.edu.pe/handle/urp/573.
Full textKarlsson, Emma, and Madelen Tram. "Undersökning av en rullstols totala miljöpåverkan." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-263935.
Full textCompany X was established in the second half of the 20th century with the goal to develop high-quality medical aids such as wheelchairs. The company strives for their users to be able to sit in a way that maximises their ability to move as well as their activity rate based on their individual prerequisites. The purpose of the project was to examine the total environmental impacts of one of Company X’s wheelchairs, used during 13 years, using a lifecycle analysis as well as providing a good foundation for future sustainability work. Based on the results gained from the lifecycle analysis suggestions that could, if possible, lower the impacts of the product should be examined. The analysis was based on two different markets. In market 1 the wheelchair is disposed of after one use, in market 2 the wheelchair is reconditioned and reused at least once before disposal. The information that was collected in the beginning of the project showed that one user uses the wheelchair for 4,3 years on average. This means that one wheelchair is used by about three users during its lifetime. In market 1, therefore, three wheelchairs that are disposed of after 4,3 years are examined and in market 2 one wheelchair that is reconditioned and reused twice before being disposed of after the third user has been examined. The project is divided into two phases, phase 1 where the wheelchair is analysed using the program SimaPro and phase 2 where suggestions to lower the impact was examined using the methods 10 Golden Principles and the 5-Layer Approach. The result from phase 1 showed that the manufacturing phase and the frame stood for the largest impact and that the reason for the high values was the manufacturing process X of aluminium. The results also showed that market 1 had an impact that was about 60% higher than that of market 2 when looking at categories such as carbon footprint, water and energy usage. To fulfil the design demands of the master thesis two redesign proposals were developed on modules and components where there were mixed materials, one was the armrest, the other the frame and the casted in leg rest sleeve. Due to the fact that the results showed Master of Science Thesis TRITA-ITM-EX 2019:669 Analysis of the environmental impact of a wheelchair Emma Karlsson Madelen Tram v that the frame had the greatest impact and that the manufacturing of it was what caused the high numbers its material and manufacturing-phase was chosen for further examination during phase 2. The developed design proposals were also examined further during this phase. The new material and manufacturing processes that were proposed and analysed were an aluminium composite and the manufacturing prosses welding, extrusion and CNC. The analysis showed that exchanging the material would lead to an increased environmental impact but a longer life span. This would result in a reduced environmental impact per year whilst an exchange of the manufacturing process would result in the opposite. The environmental impact would be reduced but so would the life span which means that the environmental impact per year would be increased. Implementing the two design proposals would lead to a reduction of the environmental impact. To reduce the total environmental impact, it is recommended to lengthen the life span of all the modules that make up the wheelchair.
Gloaguen, Pascal. "Les doléances phonétiques des porteurs de prothèses totales." Nantes, 1986. http://www.theses.fr/1986NANT1550.
Full textMuller, Philippe. "Reconstructions nasales partielles et totales : evolutions techniques recentes." Lyon 1, 1993. http://www.theses.fr/1993LYO1M310.
Full textCroset-Rebotier, Martine. "Reprise pour suppuration des prothèses totales du genou." Montpellier 1, 1990. http://www.theses.fr/1990MON11190.
Full textLarrouy, Manuel. "Nouvelles synthèses totales de la nicotianamines et d'analogues." Thesis, Montpellier 2, 2010. http://www.theses.fr/2010MON20168/document.
Full textOur work focused on developing new strategies for synthesis of nicotianamine (a natural molecule ubiquitous in plants and involved in iron transport in planta) which have been applied to the preparation of new natural and unnatural analogues. The chelating properties of a natural analogue, the thermonicotianamine, were investigated by mass spectrometry.This manuscript is organized into four chapters: the first part presents a literature review on the central role of nicotianamine in iron homeostasis in plants.After an overview of the state of the art in the synthesis of nicotianamine and its natural and non-natural analogues, we described our new synthetic strategy based on the N-alkylation reaction.To meet the need for new molecules and reduce manufacturing time we developed the first synthesis of nicotianamine and its analogues on solid phase.Finally, after a view of the state of the art on methods for analyzing phytosiderophores and their complexes with metal, chelating properties of thermonicotianamine with metals have been studied by mass spectrometry
Assarsson, Kristina, Sandra Gunnarsson, and Marcus Svalner. "Hälsoinvesteringar - ekonomiskt motiverbara utifrån sjukfrånvarons totala kostnad?" Thesis, Kristianstad University College, Department of Teacher Education, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-3234.
Full textUppsatsens syfte var att beräkna företagets totala kostnader för sjukfrånvaro och undersöka om hälsoinvesteringarna är ekonomiskt motiverbara i form av minskad sjukfrånvarokostnad.
Vid beräkning av företagets totala kostnader för sjukfrånvaron har vi utgått från Liukkonens modell som innefattar både kvarvarande- och merkostnader som uppkommer till följd av sjukfrånvaron. Modellen har sedan kompletterats med förklaringar från andra författare.
Datainsamlingen har genomförts genom semistrukturerade intervjuer med personalansvariga på tre företag. Vi valde företag i tre olika branscher; ett tjänsteföretag, ett tillverkande företag och ett sjukhus i den offentliga sektorn.
I vår undersökning fann vi att företagens redovisade kostnader för sjukfrånvaro är betydligt lägre än vad våra beräkningar visade. Detta kan till viss del förklaras med att företagen inte tar hänsyn till de kring- och merkostnader som uppkommer vid sjukfrånvaro. Konsekvenserna av detta kan vara att företagen aldrig ser de totala kostnaderna som sjukfrånvaron medför, vilket i sin tur kan leda till felaktiga investeringsbeslut. Vidare undersökte vi företagets hälsoinvesteringar och om dessa fått effekter på sjukfrånvaron. Undersökningen visade att alla tre företagen hade en minskning i sjukfrånvaro. För att kunna konkludera om det är hälsoinvesteringarna som bidragit till denna minskning har vi granskat andra faktorer som kunnat påverka resultatet. Analysen påvisade att tjänsteföretagets hälsoinvesteringar hade ett samband med minskningen av sjukfrånvaro, vilket gör investeringen ekonomiskt motiverbar. I de andra företagen kunde vi inte påvisa ett direkt samband.
För att se effekterna av lagen om särskild sjukförsäkringsavgift har vi genomfört ett förenklat exempel på tjänsteföretaget. Beräkningen visade att företaget kommer att få ökade kostnader för sjukfrånvaron från den 1 januari 2005.
Dever, Jill A. "Sampling weight calibration with estimated control totals." College Park, Md.: University of Maryland, 2008. http://hdl.handle.net/1903/8815.
Full textThesis research directed by: Joint Program in Survey Methodology. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
Gay, Michel. "Prostatectomies totales pour cancer : à propos de 69 cas." Montpellier 1, 1988. http://www.theses.fr/1988MON11348.
Full textKHAMLACH, KENZA. "Syntheses totales de la ()-trachelogenine et des lignanes apparentes." Le Mans, 1991. http://www.theses.fr/1991LEMA1004.
Full textBillard, Barbara. "Contribution à l'étude biomécanique des prothèses totales de hanche." Lyon 1, 1991. http://www.theses.fr/1991LYO10022.
Full textHenry, Olivier. "Synthèses totales de métabolites de la 15-F2t-Isoprostane." Montpellier 2, 2002. http://www.theses.fr/2002MON20009.
Full textChouteau, Julien. "Cinématique des prothèses totales de genou à plateau mobile." Lyon 1, 2008. http://www.theses.fr/2008LYO10044.
Full textWe report post operative and mid term kinematics of mobile bearing total knee arthroplasty (MB-TKA). The radiographic images were digitized using a high-resolution scanner. The 3-dimensional position and orientation of the implant components were determined using model-based shape-matching techniques. First, effects of radiograph projection parameter uncertainty on TKA kinematics from model-image registration were analyzed. Then, we performed three studies: “Sagittal laxity after posterior cruciate ligament found when retaining MB-TKA”, “Kinematics of a cementless MB PCR-TKA”, and finally, with 3D models of the metallic beads inserted in the PE insert, we studied “Mobile-bearing kinematics in PCL-retaining TKA
Gabino, Curiñahui Rocío Lizeth. "Opuntia ficus-indica como coagulante para remoción de sólidos suspendidos totales del efluente de beneficio en avícola La Chacra." Bachelor's thesis, Universidad Continental, 2018. http://repositorio.continental.edu.pe/handle/continental/5029.
Full textBouvaist, Odile, and Jean-Claude Caput. "Utilisation d'une héparine de bas poids moléculaire "Enoxaparine" dans les thromboses lors de microréimplantations totales ou sub-totales : à propos de douze observations." Bordeaux 2, 1991. http://www.theses.fr/1991BOR2M012.
Full textDe, Jesús Hernandez Gerardo Daniel. "Determinación de Mesofilos Aerobios, Coliformes Totales y Coliformes Fecales en el cultivo de cilantro ( Coriandrum sativum L.), producido en tres municipios del Estado de México." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2016. http://hdl.handle.net/20.500.11799/65576.
Full textUniversidad Autónoma del Estado de México; Facultad de Ciencias Agrícolas. Proyecto: Calidad microbiologica de tres hortalizas producidas en el Estado de México. con clave:3791/2014/CID
Ramirez, Cruz Katia Anahi. "Determinación de Mesofilos Aerobios, Coliformes Totales y Coliformes Fecales en el cultivo de espinaca ( Spinacia oleraceaL.), producido en tres municipios del Estado de México." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2017. http://hdl.handle.net/20.500.11799/65584.
Full textUniversidad Autónoma del Estado de México, Facultad de Ciencias Agrícolas. Proyecto: Calidad Microbiologica de tres hortalizas producidas en el Estado de México. clave: 3791/2014/CID
Farkas, Pierre, and Henrik Bodarve. "LHC - Strävan efter att öka den totala kundupplevelsen." Thesis, Mälardalens högskola, Akademin för hållbar samhälls- och teknikutveckling, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-12532.
Full textI dagens samhälle finns det mängder av olika erbjudanden som konsumenter ställs inför genom olika marknadsförningskanaler, där de aktivt måste välja det erbjudande som är mest tilltalande. För att ett erbjudande ska vara tilltalande så måste det ge ett mervärde i form av upplevelser. Det krävs även att erbjudandet ger underlag att skapa en tillräcklig attraktion så att kunden väljer just den produkten/tjänsten framför ett annat. Vidare bör även varje enskilt erbjudande överträffa besökarnas förväntningar, för att på sätt leverera något ”utöver det vanliga”. Vi har valt att studera hur LHC (Linköpings Hockey Klubb) arbetar med marknadsföring för att öka den totala kundupplevelsen. LHC startades som en idrottsförening vars syfte var att nå framgång inom ishockeyn, men ishockey handlar dock så mycket mer än om själva idrotten. Ishockeyklubbarna är idag stora företag vars syfte är att vara resultatrika, både sportligt och företagsekonomiskt. Idag har LHC svårigheter med att attrahera och engagera sin publik, stödet fluktuerar och relationerna med både supportrar och besökare är undermåliga. Det finns många olika sätt för hur en organisation ska kunna öka den totala kundupplevelsen. LHC arbetar mycket med sina evenemang för att stärka sitt varumärke, målet är även att ta marknadsandelar och på så sätt öka antalet besökare. I dagens Idrotts-Sverige går oftast idrottsliga framgångar och ekonomiska medgångar hand i hand, vilket medför att idrottsklubbarna måste lägga stort fokus på vad marknaden efterfrågar. En helhetsupplevelse måste skapas för att besökarna ska känna ett mervärde, dvs. att fokus inte enbart bör ligga på det sportsliga evenemanget. Utifrån ovanstående diskussion förväntas denna uppsats svara på följande frågor:Varför har LHC inte lyckats attrahera och engagera sin publik trots idrottliga framgångar? Hur arbetar LHC idag och hur borde de arbeta i framtiden för att öka den totala kundupplevelsen? För att svara och analysera på ovanstående frågor har vi tagit hjälp av den teori som föreligger inom ämnet marknadsföring där bland annat Sports Marketing, relationsmarknadsföring och upplevelserum studerats. Det empiriska materialet har bestått av ett antal intervjuer med supportrar och nyckelpersoner inom LHC:s organisation och detta material har vidare analyserats genom den kvalitativa metoden. Denna studie visar på att LHC tenderar att fokusera för mycket på hur många besökare de haft, samt hur stora intäkterna varit vid varje enskilt evenemang istället för att koncentrera sig på att möta efterfrågan. Det har även framkommit att LHC har en undermålig relation till sina supportrar och besökare och om detta skulle förbättras så skulle engagemanget hos publik och supportrar sannolikt öka. Detta skulle troligtvis även göra att klubbens ekonomiska och sportliga resultat ökar. För övrigt så spelar varumärket en stor roll och det är vikigt att LHC ständigt arbetar för att stärka och bibehålla varumärkets status. Det även av stor vikt att skapa en delaktighetskänsla hos publik och supportrar för att skapa en god atmosfär i och kring ishockeymatcherna. De bör således inte bara fokusera på evenemangen som är relaterade till ishockeyn, utan snarare sträva efter att leverera en total kundupplevelse som inkluderar alla evenemang. Detta kan sedan vara en del i den totala marknadsföringsstrategin vilket bör ha incitamenten att leverera upplevelser och mervärde för besökarna. Något som även är viktigt att beakta är personalen som arbetar med varje enskilt evenemang, dvs. att de känner engagemang och dedikation för att skapa ett mervärde för besökarna i de upplevelserum och servicemöten som förkommer. Detta kommer sedan att bidra till att LHC stärker sitt varumärke, vilket i sin tur skapar underlag för att attrahera nya kunder i form av sponsorer, investerare och slutligen fler besökare.
Potvin, Steeves. "Synthèses totales de la (-)-microcionine 2 et du (±)-déshydroambliol A." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq25713.pdf.
Full textBoisgard, Stéphane. "Migration des implants acetabulaires dans les protheses totales de hanche." Clermont-Ferrand 1, 1989. http://www.theses.fr/1989CLF11029.
Full textGILARDONE, HAOND CATHERINE. "Bilan de 1000 coloscopies totales consecutives realisees en pratique liberale." Lyon 1, 1991. http://www.theses.fr/1991LYO1M318.
Full textBazgan, Cristina. "Approximation de problemes d'optimisation et de fonctions totales de np." Paris 11, 1998. http://www.theses.fr/1998PA112297.
Full textLefebvre-Josien, Delphine. "Synthèses totales de deux cyanoglucosides : la bauhinine et le lithospermosid." Mulhouse, 2001. http://www.theses.fr/2001MULH0665.
Full textThe total synthèses of two naturally occurring non-cyanogenic cyanoglucosides have been achieved from the optically pure oxanorbomenone: Bauhinin was prepared in 12 steps and a 8% global yield, Lithospermoside in 13 steps and 9% yield. The glycosidation key-step was studied on several aglycones bearing différent acid-sensitive groups. This step was carried out by a modification of the Koenigs-Knorr procédure using bromotetraisobutyrylglucose as donor, silver triflate as promoter and an hindered pyridine as base which, afforded the desired beta-glucosides with very good yields (50%-70%). The aglycones required for the total synthèses were prepared by the stereoselective introduction of protected hydroxyle on the oxanorbomenone skeleton, followed by cyanomethylation via a Wittig-Horner reaction and by the base-induced opening of the oxa bridge. After the glycosidation, the synthèses were finished by deprotection and photoisomerization steps
DUVINAGE, JEAN-PIERRE. "Rescellement en un temps des protheses totales de hanche septiques." Lille 2, 1992. http://www.theses.fr/1992LIL2M163.
Full textTymen, Anne-Marie. "Contribution de la phonétique à la création des prothèses totales." Brest, 1990. http://www.theses.fr/1990BRES4013.
Full textAndersson, Tobias, and Rasmus Bergmark. "Värnplikten som en socialiseringsprocess : En undersökning av hur identitet formas, upprätthålls och förändras." Thesis, Uppsala universitet, Sociologiska institutionen, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-256252.
Full textHamza, Samir Pluvinage Guy. "Etude du comportement en fatigue en compression des biocéramiques (AI2O3, ZrO2) utilisées pour la conception des prothèses ostéo-articulaires." Metz : Université Metz, 2008. ftp://ftp.scd.univ-metz.fr/pub/Theses/2002/Hamza.Samir.SMZ0236.pdf.
Full textPhilippeau, Jean-Marie Gouin François. "Etude de l'incidence de l'ostéolyse acétabulaire après implantation d'une cupule Atlas® à propos de 217 prothèses à plus de 13 ans de recul /." [S.l.] : [s.n.], 2008. http://castore.univ-nantes.fr/castore/GetOAIRef?idDoc=46216.
Full textLopes, Ronny Gouin François. "Étude de la prévalence des ruptures d'inserts CÉRASUL® l'expérience nantaise de 353 implantations /." [S.l.] : [s.n.], 2009. http://castore.univ-nantes.fr/castore/GetOAIRef?idDoc=60216.
Full textJecko, Thierry. "Sections efficaces totales d'une molécule diatomique dans l'approximation de Born-Oppenheimer." Phd thesis, Université de Nantes, 1996. http://tel.archives-ouvertes.fr/tel-00007457.
Full textLéger, Olivier. "Prothèses totales de genou total condylar à 10 ans de recul." Bordeaux 2, 1993. http://www.theses.fr/1993BOR23080.
Full textMAUREL, REMI. "De l'utilisation d'obturateurs bio-degradables dans les protheses totales de hanche." Toulouse 3, 1990. http://www.theses.fr/1990TOU31107.
Full textCéruse, Philippe. "Reconstructions partielles et totales du pavillon de l'oreille : evolution, techniques recentes." Lyon 1, 1994. http://www.theses.fr/1994LYO1M221.
Full textJecko, Thierry. "Sections efficaces totales d'une molecule diatomique dans l'approximation de born-oppenheimer." Nantes, 1996. http://www.theses.fr/1996NANT2046.
Full textVANDAMME, BENEDICTE. "Syntheses totales de phospholipides amines susceptibles de presenter des proprietes antitumorales." Paris 11, 1991. http://www.theses.fr/1991PA112163.
Full textRixrath, Emmanuel. "Contributions numériques à l'étude de l'usure des prothèses totales de hanche." Aix-Marseille 2, 2008. http://theses.univ-amu.fr.lama.univ-amu.fr/2008AIX22044.pdf.
Full textIn this work, macroscopic analytical and numerical models have been developed in order to analyse the contact stress distribution between the prosthetic head and the polyethylene cup as a function of factors related to (i) the implant (clearance and cup thickness), (ii) the surgeon (cup position) and (iii) the physical activities of the patients (walking and jogging). The coupling of these different factors plays an important role in the contact stress distibution and the contact surface degradation. This coupling is fundamental to study the wear of orthopaedic implants. For an articular clearance higher than 50μm, the contact pressure increases by 40% when the inclination increases by 50° to 75°. In order to simulate the wear particles formation, a numerical model based on the particule method « Smoothed Particles Hydrodynamics » has been developed. The results obtained with this model show that degradation state of the polyethylene as well as asperity geometry of the prosthetic head play a major role in the wear particles formation. The ability of the polyethylene to create wear debris increases when the material is degraded
Lopetegui-Bourega, Corinne. "Infection des prothèses totales du genou : à propos de quinze cas." Bordeaux 2, 1992. http://www.theses.fr/1992BOR2M100.
Full textGoran, Benedeković. "Enantiodivergentna totalna sinteza odabranih stiril laktona i preliminarno ispitivanje njihove citotoksičnosti." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2012. http://dx.doi.org/10.2298/NS20121011BENEDEKOVIC.
Full textEnantiodivergent total syntheses of both (+)- and (−)-enantiomers of goniofufurone, 7-epi-goniofufurone and crassalactone C have been accomplished starting from D-glucose. The key steps of the synthe-sis of 7-epi-(+)-goniofufurone were a stereo-selective addition of phenyl magnesium bromide to a protected dialdose, followed by a stereospecific furano-lactone ring formation by condensation of a partially protected lactole with Meldrum’s acid. The synthesis of (+)-goniofufurone and (+)-crassalactone C required a configurational inversion at C-5 in the common intermediate that was efficiently achieved under the standard Mitsunobu conditions, or alternatively through a sequential oxidation of the benzylic hydroxyl group followed by a stereo-selective reduction with borohydride. A similar approach was applied to the synthesis of the unnatural enantiomers of goniofufurone, 7-epi-goniofufurone and crassalactone C, two novel, conformationally constrained analogues of both (+)- and (−)-goniofufurone (oxetanes 34 and ent-34). as well as the corresponding 7-deoxygenated derivatives (31 and ent-31). We have also developed the first total synthesis of (+)-crassalactone B (2) and an alternative synthesis of (+)-crassalactone C (3) starting from D-glucose. Finally, the synthesized styryl-lactones were evaluated for their antiproliferative activity against a panel of human tumor cell lines.
Li, Kenneth, and Adam Forsström. "Färjestad BK: Hur man bör öka den totala kundupplevelsen." Thesis, Karlstads universitet, Avdelningen för företagsekonomi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-14320.
Full textThe purpose of the essay is to examine the current marketing situation for Färjestad BK, develop proposals for improvements regarding their marketing and the customer experience that’s offered to achieve a turnaround of a negative trend. To gather information for the essay two respondents were selected, a representative from Färjestad BK and the other from Wolfpack. Qualitative personal in-depth interviews were chosen, because the authors needed as relevant and detailed information as possible. Theories in marketing, sports marketing, marketing strategy, relationship marketing and experience economy were used as a theoretical basis. The basis was chosen based on the purpose of this essay to be able to solve the prepared problem formulations. The information gathered from the interviews were described in the empirical chapter of the essay and also used as a basis for the analysis, results and conclusions. The analysis was based on the theoretical and empirical chapter and also on our own thoughts and opinions with the purpose as a starting point. In the analysis the marketing, brand, activities on and off the ice and the attendance of Färjestad BK was primarily discussed. Some emphasis was put on how Färjestad BK works today, but mostly what Färjestad BK intend to work on and should work on. The analysis and the results presented were verified by existing theories and research articles that previously studied these phenomena. In the conclusion the substantial reasons regarding the problem and the possible solutions of the problem formulation were discussed. With increased competition from television Färjestad BK needs to rethink and improve their overall product to increase the customer value. It is all about creating something extraordinary to offer the customer an experience which is unique when attending ice hockey live. Finally, factors that influences Färjestad BKs product is mentioned and how they all are connected to each other and Färjestad BK should view their product from an overall perspective.
Gustafsson, Hanna, and Olsson Karin Axelsson. "BROTTSKONCENTRATION- IDENTIFIERA BROTTSMÖNSTER GENOM BROTTSFREKVENS ELLER DET TOTALA BROTTSSKADEVÄRDET?" Thesis, Malmö universitet, Fakulteten för hälsa och samhälle (HS), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-24428.
Full textThe current study aims to investigate whether or not the neighborhoods with the highest crime rates in Malmö also are the areas with the highest crime harm. A database analysis of reported crime incidents shows that 13 of the highest crime rate neighborhoods likewise are the neighborhoods with the highest crime harm rate. Five neighborhoods are solely classified as high crime rate neighborhoods meanwhile five are classified solely as high crime harm neighborhoods. This result indicates that the crime fighting agencies should supplement their working methods against high-crime areas with methods targeting neighborhoods with high crime harm. Thereby it is possible that the crime prevention could work more efficiently. The result also shows on weak correlations between several different independent variables, linked to theory, and neighborhoods that can be classified as high crime rate neighborhoods and/or a high crime harm neighborhoods. In conclusion the study encourages for further research on the subject with focus on microplaces.