Dissertations / Theses: 'Tourette’s Syndrome'

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Buse, Judith, Clemens Kirschbaum, James F. Leckman, Alexander Münchau, and Veit Roessner. "The Modulating Role of Stress in the Onset and Course of Tourette’s Syndrome: A Review." Sage, 2014. https://tud.qucosa.de/id/qucosa%3A35434.

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Accumulating data indicate a common occurrence of tic exacerbations and periods of psychosocial stress. Patients with Tourette’s syndrome (TS) also exhibit aberrant markers of hypothalamic-pituitary-adrenal (HPA) axis activation. Based on these findings, a functional relationship between stress and tic disorders has been suggested, but the underlying mechanism of how stress may affect tic pathology remains to be elucidated. We suggest that dopaminergic and noradrenergic neurotransmission as well as immunology play a crucial role in mediating this relationship. Two possibilities of causal direction might be assumed: (a) psychosocial stress might lead to an exacerbation of tics via activation of HPA axis and subsequent changes in neurotransmission or immunology and (b) TS-related abnormalities in neurotransmission or immunology result in a higher vulnerability of affected

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Åkerlund, Tanya. "Tourettes Syndrom och tics hos skolbarn." Thesis, Stockholm University, Department of Social Work, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1179.

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Syftet med denna uppsats har varit att i en litteraturstudie ge en allmän beskrivning av Tourettes syndrom och övriga ticstillstånd, samt att granska förhållandena för barn med TS och tics i skolan och vilka förslag som i litteraturen ges på anpassad skolgång för dessa barn. Studien är en kunskapsöversikt med följande frågeställningar: Hur beskrivs Tourettes syndrom och tics i vald litteratur? Vilka problem kan ses hos barn med Tourettes syndrom och tics i skolan enligt vald litteratur? samt Vilka förslag ges i vald litteratur på anpassad skolgång eller pedagogiska insatser för barn med Tourettes syndrom eller ticsbesvär? Dessa frågeställningar har utgjort kategorier i struktureringen av materialet via meningskategorisering. Tourettes syndrom är en neuropsykiatrisk störning vars bakomliggande orsaker troligtvis är ärftlighet. Syndromet förekommer hos ungefär en halv procent av alla skolbarn som då besväras av en kombination av motoriska och vokala tics. Dessa kan ta sig uttryck som ryckningar, grimaser, blinkningar, harklingar, grymtande och skall men kan också innebära exempelvis upprepande av egna eller andras ord och fraser, tvångsmässigt uttalande av obsceniteter och socialt oacceptabla gester eller handlingar. I skolan kan barn med TS ha kognitiva problem, svårigheter att förstå och ta emot muntlig information, kontrollera impulser och ouppmärksamhet på lektioner. Retningar, mobbing, utstötning och dålig självkänsla förekommer oftare hos dessa barn jämfört med andra. I analysen används socialkonstruktionistiska och diskursanalytiska tankegångar.

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Yates, Rachel. "A randomised trial comparing Habit Reversal and psycho-education treatment groups for children with Tourette Syndrome." Thesis, Royal Holloway, University of London, 2014. http://digirep.rhul.ac.uk/items/d76ad69f-6280-111b-467f-c6b83b7ce5e7/1/.

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The quality of life of children with Tourette Syndrome, a neurodevelopmental condition characterised by chronic tics, is impacted greatly by both the symptoms themselves and their social consequences. Habit Reversal Therapy, a behavioural therapy for tic management, has substantial empirical support in its individual form, but this approach has never been investigated in a group format. Group based delivery of Habit Reversal Therapy could increase access to therapy, improve the cost-effectiveness of treatments and potentially offer additional therapeutic benefits. This randomised controlled pilot study evaluated the feasibility and preliminary efficacy of Habit Reversal Therapy compared to psycho-educational groups for 33 children aged 9 to 13 years with Tourette Syndrome and Chronic Tic Disorders. Outcomes of the groups were evaluated in terms of reductions in tic severity and improvements in quality of life. Good attendance rates in both groups suggested feasibility and acceptability of the interventions. Improvements in tic severity and quality of life were found in both groups, although to a lesser extent compared to previous studies of individual behavioural therapy for tics. Motor tic severity showed greater improvements in the Habit Reversal Therapy group on the main outcome measure (Yale Global Tic Severity Scale) but not on a direct observational measure of tic frequency. Given the potential for such groups to provide additional treatment options for families, further research is warranted. Clinical implications and suggestions for improvements to the current design for a larger study are outlined as well as indications for wider reaching future research.

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Gaynor, Colin Michael. "Biochemical aspects of Tourette's Syndrome." Thesis, Aston University, 1999. http://publications.aston.ac.uk/10961/.

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Kynurenine (KYN) is the first stable metabolite of the kynurenine pathway, the major route of tryptophan. (TRP) metabolIsm. In the liver, cortisol-inducible tIyptophan-2,3-dioxygenase (TDO) is the first enzyme and rate limiting step. In extrahepatic tissues, it is superceded by indoleamine-2,3-dioxygenase (IDO), an enzyme with a wider substrate specificity. Earlier work in this research group has found substantial elevations in plasma KYN in fasting Tourette's Syndrome (TS) patients with normal TRP and neopterin. The aim of our initial pilot study was to confirm this increase in KYN in fasting human TS patients compared with normal controls, and to see how changes in diet :ay influence certain kynurenine pathway variables. However, we failed to detect a change in plasma KYN, TRP, kynurenic acid (KYNA), neopterin or cortisol between the fasting TS and control groups. Moreover, none of the variables was affected by dietary status, and thus candidates selected for the larger cross-sectional study were permitted to eat and drink freely on the day that blood samples were submitted, but were requested to avoid products containing caffeine, aspirin or nicotine. In the cross-sectional study, TS patients exhibited significantly higher plasma KYN concentrations than controls, although the magnitude of the change was much smaller than originally found. This may be due to differences in detection procedure and the seasonal fluctuation of some biochemical variables, notably cortisol. The generalised increase in neopterin in the TS subject group, suggests a difference in the activity of cytokine-inducible IDO as a likely source for this elevated KYN. Other kynurenine pathway metabolites, specifIcally TRP, 3-hydroxykynurenine (HKY), 3-hydroxyanthranilic acid (HAA) and KYNA were unchanged. In view of recent speculation of the potential therapeutic effects of nicotine in TS, the lower KYN concentrations observed in TS smokers, compared with non-smoking TS patients, was another interesting finding. Tic-like movements, such as head-shakes (HS), which occur in rodents both spontaneously and following diverse drug treatments, closely resemble tic behaviours in humans. The animal tic model was used to examine what effects nicotine may have on shaking behaviours and on selected TRP metabolites. Acute systemic administration of nicotine to mice, produced a dose-dependent reduction in HS frequency (induced by the 5-HT2A/2C agonist DOl), which appeared to be mediated via central nicotinic cholinergic receptors, since mecamylamine pretreatment abolished this effect. Conversely, twice daily subcutaneous injections of nicotine for 7 days, led to an increase in spontaneous and DOI-induced HS. Chronic nicotine also caused a significant elevation m plasma and whole brain KYN concentrations, but plasma TRP, HKY, HAA and KYNA were unaltered. In addition, no change in brain 5-HT or 5-HIAA concentrations or 5-HT turnover, was found. Despite contrasting results from human and animal studIes, a role for nicotine in the mediation of tic-like movements is indicated. The relevance of the kynurenine pathway to TS and the potential role played by nicotine in modifying tic-like behaviours is discussed.

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Nuernberger, Judith. "Tourette Syndrom." Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-86612.

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Glass, Åsa. "Att leva med Tourettes syndrom : En litteraturöversikt." Thesis, Högskolan i Skövde, Institutionen för hälsa och lärande, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-16361.

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Bakgrund: Tourettes syndrom är en neuropsykiatrisk funktionsnedsättning som karaktäriseras av tics. Tics är ofrivilliga, återkommande ljud, rörelser och handlingar. Syndromet förekommer ofta tillsammans med andra diagnoser och kan orsaka ett stort lidande. Syfte: Studiens syfte är att beskriva människors upplevelse av att leva med Tourettes syndrom. Metod: Studien är en litteraturöversikt baserad på elva empiriska, vetenskapliga artiklar. Resultat: Resultatet delas in i fem teman. En del av identitetenbelyser att TS inverkar på identiteten och hur den utvecklas. Nedsatt livskvalitet tar upp att samsjukliga diagnoser och svårare tics ger ökad risk för ytterligare svårigheter och sänkt livskvalitet. Olika former av funktionsnedsättning framhäver att TS är en fysisk, psykisk och känslomässig nedsättning. Strategier för att hantera symtom beskriver strategier som att undertrycka, ignorera eller maskera tics i sociala sammanhang. Social interaktion visar att negativ respons från andra är vanligt samt att nära relationer är den viktigaste faktorn för att kunna må bra trots sin nedsättning. Slutsats: Upplevelsen av att leva med Tourettes syndrom är övervägande negativ. Syndromet inverkar på identitet, livskvalitet och relationer, vilket skapar lidande. Det påverkar även fysiska, psykiska och yrkesmässiga faktorer. Detta är viktig kunskap för sjuksköterskor inom olika vårdkontexter.

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Hazen, Holly. "Tourette syndrome a review of literature on what educators know and how to better help students with the disorder /." Online version, 2009. http://www.uwstout.edu/lib/thesis/2009/2009hazenh.pdf.

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Carnochan, Jean Kathleen. "Tourette's syndrome and primary education : child and teacher perceptions." Thesis, University of Bristol, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616638.

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This study illustrates the creation, exploration and analysis of the narratives of five primary school children with a diagnosis of Tourette's syndrome (TS). Additionally it provides the analysis of thematic data gathered from semi-structured interviews conducted with their teachers which focused upon the teachers' perspectives of teaching a child with TS. The aims of this study are to: to gauge a better understanding of the children's views of their TS and their primary school experience; consider the interactions within this environment; and consider interventions and approaches that might support children in primary school. The children participating in this study do not wish to be defined by their TS, and they make semi-successful attempts to supress tics. However, their limited success at tic suppression sometimes leads to misinterpretation by teachers of the nature of tics. The children's attempts to suppress their tics and others' misinterpreted responses may have implications for their emotional development and access to learning. The children's teachers report a lack of easily accessible information about TS. Subsequently, they feel unsupported and unknowledgeable about how to provide effective support; instead, they build knowledge and understanding through experience. Having a 'sanctuary' within school and an adult to advocate on their behalf is cited as a potentially supportive strategy. Peer support and peer education are also thought to be of value; however, there are exceptions, making it important to listen to individual children about their perceived support needs. Implications for Educational Psychologist's practice and the limitations of this study are also discussed.

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Drury, H. M. "Social-emotional processing and executive functions in Tourette's syndrome." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1318075/.

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Tourette’s syndrome (TS) is a neurodevelopmental disorder often associated with social difficulties and inappropriate behaviours (e.g. Kurlan et al., 1996). These behavioural difficulties may indicate impairment on aspects of social-emotional processing, but may also be related to impairments in executive functions which have been reported in TS, particularly for aspects of inhibition. This thesis aims to examine different aspects of social-emotional processing and executive functions in TS, and to assess the possible contribution of executive processes. A series of experimental studies was conducted to compare those with TS to healthy matched control participants. With respect to social-emotional processing, ability to decode social-emotional cues, to regulate emotional experience, and to regulate social behaviour according to context, and possible executive contributions to these processes were examined. Further studies extended previous research by examining inhibitory functions not previously assessed in TS, and explored the contribution of task complexity to inhibitory performance. The findings of the experimental studies are considered in the context of recent models of social-emotional processing (Ochsner, 2008), executive functions (Miyake et al., 2000) and inhibition (Nigg, 2000). Several alternative explanations of the findings of this thesis were identified: selective inhibitory impairment, level of executive task demands, or multiple deficits in executive and social-emotional processing. The applicability of these different explanations to the findings is discussed, and the implications of the findings are reviewed.

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Mason, Damon. "Implicit sequence learning in Gilles de la Tourette's syndrome." Thesis, University of Birmingham, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422724.

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Rybak, Celina. "Tourette's Syndrome from a social work perspective : an exploratory study." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=22710.

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Tourette's syndrome (TS) is a chronic movement disorder characterized by motor and vocal tics. This report looks at TS through the eyes of three families and two adults diagnosed with the syndrome. The social and psychological reactions and adjustment to the disorder are examined. Three approaches were used to explore the issues: a literature review; field notes and unstructured biographical interviews. Social and psychological reactions include: depression, withdrawal and suicidal ideation. Unresponsiveness on the part of the health care and social service systems contributed to feelings of anger, powerlessness, guilt and shame. The families' and individuals' ability to lobby for services was an important factor in enhancing adjustment. TS is a multi-faceted disorder; it serves as a paradigm for issues and problems that are best served by a multi-disciplinary approach. Services must be coordinated; a case management approach would facilitate efficient coordination and delivery of services.

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Dehning, Sandra. "Chromosomen-Screening bei Tourette-Syndrom." Diss., kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/9009/.

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Shahana, Nasrin. "Sensory Dysfunction in Children with Tourette Syndrome." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1445609142.

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Harter, C. "Characterising the comorbid subtypes of Tourette syndrome." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444733/.

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Tourette syndrome (TS) is a neurodevelopmental disability characterised by a cognitive profile of executive function deficits, particularly relating to inhibitory control. There is much evidence that TS is likely to occur comorbidly with other disorders and that this may exacerbate the presence of cognitive disruptions. Attention Deficit Hyperactivity Disorder (ADHD) is one of the neurodevelopmental disorders that TS often occurs comorbidly with. This review provides an examination of TS including its clinical presentation, aetiology, comorbidities and cognitive profiles. A similar discussion is followed for ADHD. This leads to an examination of the key processes and measures of attention and inhibition with reference to these disorders. It is hoped that by examining these shared profiles, it might lead to a greater understanding of the overlap between these two neurodevelopmental disorders.

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Stephens, Robyn J. "Aggressive behavior in children with Tourette's Syndrome and associated disorders." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0024/MQ34003.pdf.

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Evans, Rob. "Gilles de la Tourette's Syndrome : research from a critical perspective." Thesis, Manchester Metropolitan University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392833.

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Cornejo, Leticia. "School Psychologists’ Training and Knowledge of Tourette Syndrome." Chapman University Digital Commons, 2015. https://digitalcommons.chapman.edu/ces_dissertations/15.

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A web-based survey was conducted that included 97 practicing school psychologists in California. The results from the survey indicated that the majority (88%) of respondents were knowledgeable about Tourette Syndrome. Many respondents (28%) had never worked with a student with Tourette’s, 20% had at least one case, and 52% indicated that they had worked with more than two cases in their careers as school psychologists. The majority of respondents indicated that their school psychology program did not adequately train them to assess or counsel students with Tourette’s. The majority of participants also did not feel confident to work with students with Tourette’s. As found in the study, school psychologists are in need of training to better serve children with Tourette Syndrome. Children, whether diagnosed with Tourette Syndrome or not, may exhibit difficulties making academic progress because of tic related issues, as well as comorbid disorders such as Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD). Schools typically are where students spend many hours of their day, and where those who are knowledgeable about Tourette’s can identify and provide needed supports depending on the student’s needs. Therefore, school psychologists play a key role in facilitating proper education regarding Tourette’s to students, teachers, staff, and families, as well as providing academic, behavioral, emotional, and social support a student may need.

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Khalifa, Najah. "Tourette Syndrome and Tic Disorders in a Swedish School Population : Prevalence, Clinical Assessment, Background, Psychopathology, and Cognitive Function." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6334.

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Resch, Romana. "Tourette-Syndrom: Immunerkrankung, Entzündung oder Neuroakanthozytose?" Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-68567.

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Weidinger, Elif. "Antikörpertiter bei Schizophrenie und Tourette Syndrom." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-156238.

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Donaher, Joseph Gerard. "SPEECH FLUENCY DEMONSTRATED BY CHILDREN WITH TOURETTE SYNDROME." Diss., Temple University Libraries, 2008. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/7333.

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Communication Sciences
Ph.D.
Children with Tourette Syndrome (CWTS) frequently exhibit a high prevalence of disfluent speech behaviors which are often labeled stuttering. The present study analyzed the fluency characteristics of CWTS, in comparison to children who stutter (CWS) and typically developing peers (TDP). It was predicted that CWTS would be less fluent than TDP but more fluent than CWS. A related purpose was to explore whether differences existed in the pattern of disfluencies demonstrated by these groups. To this end, it was predicted that CWTS would demonstrate significantly lower proportions of stuttering-like disfluencies than CWS and significantly higher proportions of stuttering-like disfluencies than TDP. Participants included eight CWTS, eight CWS and eight TDP. Speech samples, collected during a narrative story telling task, were analyzed to determine whether significant differences in the type and frequency of disfluencies were evident between the groups. Results revealed that CWTS were significantly more fluent than CWS and that CWTS produced significantly lower proportions of stuttering-like disfluencies than CWS. Although not statistically significant, CWTS were twice as disfluent as TDP and CWTS produced significantly higher proportions of stuttering-like disfluencies than TDP. These findings confirmed that CWTS present with an atypical disfluency pattern which can be differentiated from that of CWS and TDP based on the total disfluency level and the proportion of stuttering-like disfluencies.
Temple University--Theses

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Wildenauer, Agnes. "Untersuchungen zur Monozyten-Stimulierbarkeit bei Tourette-Syndrom." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-137119.

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Klug, Birgit. "Familienuntersuchung zum Gilles-de-la-Tourette-Syndrom." [S.l.] : [s.n.], 2003. http://archiv.ub.uni-marburg.de/diss/z2003/0418/.

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Howells, Debra 1975. "Fronto-striatal mechanisms in adults with Tourette's Syndrome and obsessive-compulsive disorder." Monash University, Dept. of Psychology, 2001. http://arrow.monash.edu.au/hdl/1959.1/9000.

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Sasnett, Roger Harris. "The Lived Experience of Parenting Children with Tourette's Syndrome: A Phenomenological Study." Columbus, Ohio : Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1211321903.

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McGinley, Emmett W. "Psychological, Pharmaceutical, or Neurosurgical: A Meta-Analysis of Treatments for Tourette's Syndrome." Marietta College Honors Theses / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=marhonors1211115706.

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Svensson, Emma, and Ratchadaphorn Phongsiri. "Att ha ett barn med Tourettes syndrom : - Ur ett anhörigperspektiv." Thesis, Linnéuniversitetet, Institutionen för hälso- och vårdvetenskap (HV), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-95527.

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Bakgrund: Tourettes syndrom är en neuropsykiatrisk funktionsnedsättning som upptäcks innan 18 års ålder och utgörs av ofrivilliga vokala- och motoriska tics. Tourettes syndrom hos barnet påverkar hela familjen då de är involverade i varandras liv, där förändringar i en del påverkar helheten i familjesystemet. Syfte: Syftet var att belysa anhörigas upplevelser av barn som har Tourettes syndrom. Metod: Litteraturstudie genomfördes och åtta artiklar både kvantitativa och kvalitativa, valdes ut efter kvalitetsgranskning. Artiklarnas resultat analyserades och sammanställdes till olika kategorier. Resultat: Resultatet sammanställdes till fyra olika kategorier. Resultatet indikerade på ökad stress och oro för de flesta anhöriga i samband med att ha ett barn med Tourettes syndrom. Upplevelse av lägre självkänsla, social isolering och skuld var också någonting som många upplevde på grund av barnets beteende. Det fanns även en brist på förståelse och stöd från både skola och vården. Slutsats: Anhöriga blev påverkade av olika situationer kring barnet med Tourettes syndrom som minskade deras livskvalité. För att anhöriga ska kunna få stöd i samhället och känna sig trygga behöver både skolor och vården öka kunskaperna kring hanteringen av Tourettes syndrom.

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Stenborg, Malin, and Alexandra Livh. "Skolkuratorers kunskap och erfarenhet om tics och Tourette syndrom : En kvalitativ intervjustudie." Thesis, Linnéuniversitetet, Institutionen för socialt arbete (SA), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-29120.

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The aim of this study was to examine the knowledge and the experience that school counsellors have about tics and Tourette syndrome. This study is based on a qualitative research which we conducted with semi-structured interviews. We have done five interviews with different school counsellors in a small municipality in southern Sweden. The theoretical approach that was used in this study was theory of knowledge as a comprehensive theory and professional competence which includes formal knowledge and tacit knowledge. Some of the study’s conclusions are that the School Counsellors had different professional competence about tics and Tourette syndrome. The school counsellors had received their knowledge through formal educations and work experience. School counsellors had different types of education which mean that they had different knowledge and experiences but also different approaches, methods and way to relate students with tics and Tourette syndrome in their profession. In our results, it appears that work experience and formal education often exist together. Therefore it is not possible to say which specific form of knowledge school counsellors use in a meeting with a student with tics and Tourette syndrome, and whether this could have affected the meeting.

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Ganos, Christos [Verfasser]. "Volitional inhibition of tics in Tourette syndrome / Christos Ganos." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2020. http://d-nb.info/1203309198/34.

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Nussey, C. C. "An evaluation of a classroom presentation about Tourette Syndrome." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1325633/.

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The thesis comprises three parts - a literature review, empirical paper and critical appraisal. The literature review appraises studies examining interventions giving information (or diagnostic label) about Tourette Syndrome (TS) and attention-deficit/hyperactivity disorder to parents, teachers and peers of individuals with the conditions. The empirical paper evaluates the impact of a psychosocial intervention (classroom presentation) for TS in a naturalistic setting from multiple perspective. It utilises a multiple case study design with primarily qualitative methods and quantitative questionnaires. The critical appraisal offers the author's reflections on the research process.

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Nürnberger, Judith. "Tourette Syndrom : immunologische Untersuchungen von Monozyten und Zytokinen." kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/8661/.

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Antonsson, Jesper, and Robin Johansson. "Att leva med ofrivilliga ljud och rörelser : - upplevelser av Tourettes syndrom." Thesis, Högskolan i Halmstad, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-33088.

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Tourettes syndrom är ett neuropsykiatriskt tillstånd som kännetecknas av ticks, vilket är ofrivilliga rörelser och verbala läten. Tourettes syndrom förekommer hos 1 % av världsbefolkningen. Syndromet debuterar oftast mellan 3–10 års ålder och försvinner eller reduceras vanligen före 18 års ålder. Syftet med studien var att belysa personers upplevelser av att leva med Tourettes syndrom. Uppsatsen genomfördes som en allmän litteraturstudie där elva vetenskapliga artiklar analyserades. Följande huvudkategorier framkom i resultatet: upplevelser av att vara i sociala sammanhang samt upplevelser av att hantera tillvaron. Resultatet påvisade att personer med Tourettes syndrom upplevde svårigheter i sociala sammanhang, stigmatisering och att kamrater var viktiga i vardagen. Då knapphändig forskning finns om hur det är att leva med Tourettes syndrom, är det av vikt att sjuksköterskan får ökad förståelse om syndromet för att kunna personcentrera omvårdnaden.
Tourette syndrome is a neuropsychiatric disorder characterized by ticks, which is involuntary movements and verbal sounds. Tourette syndrome affects 1% of the world population. The syndrome has it´s onset usually between 3-10 years of age and disappears or is reduced usually before the age of 18. The purpose of the study was to illuminate people's experiences of living with Tourette syndrome. The essay was carried out as a literature study where eleven scientific articles were analyzed and summarized. The following main categories emerged in the result: experiences of being in social situations and experiences of handling life. The results showed that people with Tourette syndrome experienced difficulties in social contexts, stigma and that peers were important in everyday life. Then there is scant research about what it's like to live with Tourette syndrome, it is important that the nurse gain a greater understanding about the syndrome to be able to give person-centered care.

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Curd, Kacie L. "The Neuroanatomical Functions of Tourette Syndrome and a Treatment Analysis." Scholarship @ Claremont, 2012. http://scholarship.claremont.edu/cmc_theses/315.

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The etiology of Tourette syndrome has been elusive for researchers ever since its discovery, making treatment especially difficult. After proving the disorder was organic in the second half of the 20th century, researchers have been creating theories of the underlying neural basis for Tourette’s symptomatology. These theories include abnormalities in brain structure, dysregulation of the dopamine system, dysregulation of the serotonin system and overall neurotransmitter system interactions. The etiology is likely a complex combination of all of these. Treatments for this disorder include pharmacological, behavioral and surgical. I believe the best approach for treatment is behavioral first, followed by pharmacological if behavioral does not work, and then surgical as a last resort if the previous two do not show results.

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Diaz, Anzaldua Adriana. "Genetic investigation of Tourette syndrome in the French Canadian population." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18194.

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Tourette syndrome (TS) is a childhood-onset neuropsychiatric disorder characterized by multiple motor and one or more phonic tics. TS affects all races and ethnic groups and its prevalence is estimated to be 1% of school children who are 6 to 17 years old. The etiology of this disorder is unknown, but there is strong evidence that supports the involvement of genetic factors. No specific gene unequivocally increasing the risk for TS has been identified. However, positive linkage and association studies, as well as chromosomal anomalies have been reported in the past. The aim of this study was to search for genetic variants associated with TS as a step towards the elucidation of the causes of the disorder. This study represents the first population-based genetic analysis of TS in the French Canadian population, a genetically homogenous group with respect to typical outbred human populations. We found associations between TS and variants in two dopaminergic genes, the dopamine D4 receptor and the Monoamine oxidase genes. Furthermore, we identified a new locus on chromosome 7, flanked by Dock 4 and FoxP2 genes, within a larger region previously suggested as candidate for TS by cytogenetic studies. Our results illustrate the multifactorial etiology of TS in the French Canadian population. It is probable that there is locus heterogeneity for TS even in homogenous populations such as the French Canadians in Quebec, which adds to the complexity of the involvement of non-genetic factors.
Le syndrome Gilles de la Tourette (SGT) est une affection neuropsychiatrique caractérisée par de multiples tics moteurs ainsi qu’un ou plusieurs tics vocaux. Chez les écoliers de 6 à 17 ans, la fréquence de la maladie est estimée à environ 1%. Elle touche tous les groupes ethniques. La cause du syndrome n’est pas connue, mais des facteurs génétiques jouent très probablement un rôle important, même si aucun gène augmentant les risques d’exprimer le SGT n’a encore été identifié formellement. Seules des études de linkage positives ainsi que des anomalies chromosomiques ont pour l’instant été rapportées. La recherche de variants génétiques associés au SGT était le but de cette étude; et ce, dans l’optique d’une meilleure compréhension des causes de cette maladie. Cette étude présente les premières analyses génétiques du SGT basées sur une population précise : les Canadiens-français. La relative homogénéité génétique de ce groupe est un facteur important pour ce type de recherche. Plusieurs variants appartenant à deux gènes dopaminergiques se sont avérés être associés à la maladie chez les Canadiens-français. Ces deux gènes sont le récepteur de dopamine D4 ainsi que le gène de la monoamine oxydase. De plus, nous proposons un nouveau locus sur le chromosome 7 comprenant les gènes Dock4 et FoxP2, dans une région auparavant suggérée par des études cytogénétiques. Les résultats présentés ici illustrent bien les multiples causes du syndrome de Tourette dans la population canadienne-française. L’hétérogénéité des locus est très probable, même dans une population homogène comme c’est le cas ici. Cette hétérogénéité doublée de l’influence de facteurs environnementaux rend les études génétiques beaucoup plus complexes. fr

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Liao, Sheng-Hui. "Daily functioning of children with Tourette syndrome| An exploratory study." Thesis, State University of New York at Buffalo, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=1600781.

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Objective: This retrospective study sought to identify the functional limitations in occupations, body functions, and performance skills, during periods of increased symptoms (waxing periods) and periods of decreased symptoms (waning periods) in children with Tourette syndrome (TS). Additionally, relevant demographic and health factors and frequency of occupational therapy intervention were explored.

Method: Parents of 32 children with TS under the age of 18 participated in an online survey based on the Occupational Therapy Practice Framework: Domain and Process – Third Edition.

Results: The children with TS experienced difficulty in functional performance of all occupations, body functions, and performance skills to varying degrees during a waxing period, with the majority experiencing difficulty in sleep, rest, handwriting, participating in organized activities, all mental functions, tactile (touch) perception, and ability to suppress tics.. Demographic and health factors predicting functional limitations in theses areas were age, gender, and the comorbid symptoms of anxiety disorders and sensory processing disorder. Fewer than one-third of the children had ever received occupational therapy intervention.

Conclusion: These results suggest a strong role for occupational therapy during evaluation and intervention for children with TS. The findings could be used to guide occupational therapy practice and provide basic knowledge for parents and other related professionals to support the daily functioning of these children. Future research exploring the effectiveness of occupational therapy intervention including those aimed at sensory processing, tic management, and anxiety symptom reduction is needed.

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Sims, Deanna. "Adlerian Personality Priorities of Siblings of Individuals with Tourette Syndrome." Thesis, University of North Texas, 1998. https://digital.library.unt.edu/ark:/67531/metadc278606/.

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This study was designed to examine Adlerian personality priorities of siblings of individuals with Tourette Syndrome (TS). This study aimed to investigate whether a difference exists between TS siblings and siblings of those without disabilities on variables related to personality priorities. It was hypothesized that TS siblings would score significantly higher than the control group on the superiority and pleasing personality priorities and significantly lower on the comfort and control personality priorities. Both of the hypotheses were rejected. First, no significant difference was found between TS siblings and the control group on the superiority and pleasing personality priorities. Second, no significant difference was found between TS siblings and the control group on the comfort personality priority, and TS siblings scored significantly higher than the control group on the control personality priority.

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Fine, Jason A. "Understanding the Impact of Teacher Preparation Related to Tourette Syndrome." Miami University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=miami1584463978284961.

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Deranlot, Fabienne. "Maladie des tics chroniques et multiples : syndrome de Gilles de La Tourette, revue de la littérature." Bordeaux 2, 1996. http://www.theses.fr/1996BOR2M138.

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Larsson, Susanne, and Pia Nyqvist. "Koncentrationssvårigheter : Svårighet eller möjlighet." Thesis, Mälardalen University, School of Education, Culture and Communication, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-4604.

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Isaacs, Cloes Kelly M. "Functional Impairment in Children with Tourette Syndrome: Parent and Child Agreement." Xavier University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=xavier1510248121232777.

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41

Howson, Anne L. "Clinical and attentional effects of acute nicotine treatment in Tourette syndrome." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ66157.pdf.

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Eapen, Valsamma. "Pathogenesis of Gilles de la Tourette Syndrome : clues from clinical phenotypes." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243963.

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Brett, Peter Mark. "The genetics of Gilles de la Tourette Syndrome : a linkage study." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243330.

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Farber, Robert H. "Ocular motor system functioning in obsessive-compulsive disorder and Tourette syndrome /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC IP addresses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p9917950.

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45

Cutler, D. "The Quality of Life of young people affected by Tourette Syndrome." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1444618/.

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This review considers how young people's Quality of Life (QoL) is affected by the symptoms of Tourette Syndrome (TS). The construct of QoL aims to capture how satisfied a person is with their level of functioning in life, rather than assuming that those with mild symptoms have a higher QoL than those with severe symptoms. This may be particularly relevant in TS, where a strong relationship between symptom severity and well-being has not been established. The research into QoL in TS is limited, but there is a wide body of evidence that suggests TS can impair functioning across many domains. This research reminds us that individuals with TS are coping with more than just tics. Rage attacks, attention and learning difficulties, obsessions and compulsions are also experienced by individuals with TS and can have an equally significant impact on their life.

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46

Johansson, Anna, and Sandra Jönsson. "Barn med DAMP, ADHD, Tourette syndrom och Asperger syndrom - hur kan deras skolverksamhet underlättas?" Thesis, Kristianstad University College, Department of Teacher Education, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-3637.

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Huvudsyftet med den här studien var att ta reda på hur vi som pedagoger kan hjälpa barn som är i behov av särskilt stöd för att underlätta deras skolverksamhet. Vi ville även få ökad förståelse och kunskap om vad DAMP, ADHD, Tourette syndrom och Asperger syndrom är och hur de olika symtomdiagnoserna kännetecknas.

Vi har genomfört kvalitativa intervjuer med nyckelpersoner inom detta ämne. Syftet med intervjuerna var att ta reda på hur intervjupersonerna anser att man ska arbeta med barn i behov av särskilt stöd i skolverksamheten. I undersökningen intervjuade vi en rektor, två specialpedagoger och två förskollärare.

Vår slutsats är att det inte finns någon färdig mall för hur pedagoger skall arbeta med barn i behov av särskilt stöd. Det är upp till pedagogen att lära känna varje individ och anpassa undervisningen och andra aktiviteter efter barnens utvecklingsnivå. Barn i behov av särskilt stöd har olika svårigheter och olika talanger.

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47

Thompson, Miles. "Mutation screening of dopamine and serotonin candidate genes in Tourette's syndrome and alcohol-dependent patients." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29330.pdf.

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Malli, Melina Aikaterini. "Adolescents' perceptions of their peers with Tourette's syndrome : does a brief anti-stigma intervention help?" Thesis, University of Kent, 2018. https://kar.kent.ac.uk/70039/.

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Background and aim: Tourette's syndrome is a neurodevelopmental condition characterised by tics. It is a condition that has been stigmatised by the public. School age children and especially adolescents often experience rejection from their typically developing peers due to their symptomology which could hinder school inclusion and social participation. Therefore, there is a need for implementing interventions to target typically developing peers' inaccurate knowledge about TS, and their negative attitudes. There is also a paucity of studies that explore the motivation of peers who stigmatise against people with TS. Understanding stigma and its underlying causes, however, is vital to develop effective interventions that can minimise and help to eventually eradicate stigma. The aim of the thesis is therefore three-fold: firstly, to understand how individuals with TS were perceived by typically developing adolescents. Secondly, based on these attitudes, to develop a tailor-made anti-stigma intervention; and thirdly to evaluate the effectiveness of the developed intervention within a secondary school classroom setting. Method: A sequential mixed-method design was used. Qualitative data were collected to capture tic-free adolescents' motives, and reasoning involved in the exclusion of individuals with TS. These findings were then used to design a tailor- made intervention and research measures. A randomised cluster control trial with a mixed-model design was used to determine the impact of the developed intervention on tic-free adolescents' awareness of Tourette's syndrome, attitudes, and behaviours towards individuals with TS. Data were collected at three time points: pre-intervention, post-intervention and 9 weeks after its implementation. This is the first intervention that was specifically designed for adolescents and with an assessment at a follow-up stage. Results: The qualitative study indicated that adolescents understanding about the condition was construed from misconceptions, unfamiliarity and unanswered questions. Furthermore, people with TS were either perceived as being deprived of agency and strength or as deserving pity, and in need of support. These findings helped design the intervention which was implanted on Year Ten students in a school in the South East. Upon completion of the intervention, positive changes were recorded relating to students' awareness, attitudes and behavioural intentions. Tic-free adolescents were more willing to embrace diversity within the classroom and rejected previously held notions of ableism. However, only changes in awareness were maintained at the 9-weeks follow-up. Conclusion: Tailor-made interventions can contribute substantially to preventing consolidation of unfavourable attitudes towards individuals with TS. Future research should however place emphasis on how these positive outcomes could be maintained over time. Implications of these findings for school curricula and mental health policy, as well as suggestions for future research, are discussed.

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Bailey, Malgorzata. "Executive functions in children with Tourette Syndrome : the confounding effects of comorbid attention deficit hyperactivity disorder /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19284.pdf.

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Khoury, Rita. "Perceptions of FQOL of families who have a child with Tourette syndrome." Thesis, Anglia Ruskin University, 2010. http://arro.anglia.ac.uk/211450/.

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The Family Quality Of Life (FQOL) of families who have a child with Tourette Syndrome (TS) has not yet been investigated globally. The purpose of this study was to gather data and listen to the voices and opinions of families of children with TS in order to examine the extent to which the existence of a child with TS, in the family, affected their FQOL. The research was conducted according to the mixed methods approach, combining quantitative and qualitative methods. Data was collected concerning the research population that included all the families who have a child with TS living at home, and registered at the Tourette Syndrome Organisation in Israel. Additionally, semi-structured interviews were conducted with 10 of these 25 families of children with TS. The questionnaire was analysed statistically and the interviews were analysed using a content analysis method. Conclusions derived from the research findings allowed the emergence of the ACEIST model, including five new sub-domains of FQOL that reflect the experiences of the studied families: Advocacy, cooperation, explanation, information, and severity of TS. This is a new way to view FQOL of families having a child with TS, very precise and operative and specific to those families. This ACEIST model fills the gap in knowledge identified in this field, contributing to knowledge regarding FQOL of families who have a child with TS. The new model has practical implications for the education, social and health policies in Israel regarding families who have a child with TS.

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Dissertations / Theses on the topic 'Tourette’s Syndrome'

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