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Dissertations / Theses on the topic 'Toxiciteit'

Author: Grafiati

Published: 4 June 2021

Last updated: 3 March 2023

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1

Kardinaal, Willem Edwin Adrianus. "Who's bad? molecular identification reveals seasonal dynamics of toxic and non-toxic freshwater cyanobacteria /." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2007. http://dare.uva.nl/document/51515.

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2

Hage, Annemarie. "Biocatalytic conversions by white-rot fungi: exploring the reductive enzyme system." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2001. http://dare.uva.nl/document/58083.

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Proefschrift Universiteit van Amsterdam.<br>Research carried out as part of the Innovation oriented research programme on catalysis (IOP Katalyse, no. IKA 94046) Met lit. opg. - Met samenvatting in het Nederlands.

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3

Vliet, Cornelis van. "Organic solvent exposure and neuropsychiatric disorders results from an epidemiological study among Dutch painters and construction workers /." Maastricht : Maastricht : Datawyse ; University Library, Maastricht University [Host], 1989. http://arno.unimaas.nl/show.cgi?fid=5532.

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4

Shahrour, Ola. "Kemikalier hos frisörer : Ekotoxikologisk farobedömning." Thesis, Linnéuniversitetet, Institutionen för biologi och miljö (BOM), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-39025.

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Studien undersöker vilka kemikalier som används i frisersalonger och som kan vara farliga för miljön. Största delen av kemikalierna sprids till vattenmiljön genom avloppsvatten, där exponering för vattenlevande organismer kan orsaka förändringar. En ekotoxikologisk farobedömning identifierar och karakteriserar kemikaliers risker och toxicitet. Farobedömningen baseras på tester utförda på de trofiska nivåer som finns i den akvatiska miljön och bygger på tre kriterier: akvatisk toxicitet, nedbrytbarhet och bioackumulerbarhet. Syftet med examensarbetet är att genomföra en farobedömning på kemikal

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5

Deveaux, Philippe. "Toxicite cardiaque du cisplatyl*." Nancy 1, 1994. http://www.theses.fr/1994NAN11039.

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6

BERGER, VIRGINIE. "Toxicite pulmonaire du nilutamide." Nantes, 1993. http://www.theses.fr/1993NANT262M.

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7

MALOGNE, HERVE. "La toxicite hepatique des benzodiazepines." Amiens, 1993. http://www.theses.fr/1993AMIEM013.

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8

YERROUM, MOHAMMED. "Toxicite mitochondriale de l'azt ; implication du stress oxydant dans l'expression de la toxicite chez le rat." Paris 12, 2000. http://www.theses.fr/2000PA120043.

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L'utilisation prolongee de l'azt dans le traitement de l'infection par le vih induit une myopathie mitochondriale toxique reversible. Le stress oxydant pourrait etre un cofacteur de la toxicite mitochondriale de l'azt. Dans un premier temps, nous avons precise la nature du dysfonctionnement mitochondrial induit par l'azt chez l'homme en etudiant l'expression musculaire des sous-unites de la cytochrome c oxydase chez les patients atteints de myopathie a l'azt. Nous avons montre une baisse des sous-unites d'origine mitochondriale et d'origine nucleaire, ainsi que l'existence d'un deficit segment

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9

Berton, Pierre. "La toxicite des dioxines chez l'homme." Lille 2, 1991. http://www.theses.fr/1991LIL2M372.

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10

Paranjpe, Avina. "Mechanisms and prevention of material toxicities in dentistry." Diss., Restricted to subscribing institutions, 2007. http://proquest.umi.com/pqdweb?did=1472130861&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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11

Nahar, Kazi Jannatun. "Mechanisms of immune checkpoint inhibitor-induced gastrointestinal toxicities." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29500.

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Monoclonal antibodies against immune checkpoints such as CTLA-4 and PD-1/PD-L1 have improved response and survival outcomes in advanced melanoma. While improving anti-tumour responses, they can also give rise to atypical inflammatory side effects known as immune-related adverse events (irAEs). Gastrointestinal irAEs, mainly colitis can lead to significant morbidity and cessation of treatment. It is important to identify characteristics and potential mechanisms of colitis to guide treatments without compromising their outcomes. Therefore, the thesis aimed to define the characteristics of coliti

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12

DIDES, PIERRE-YVES. "Toxicite de la vitamine a ou retinol." Nice, 1991. http://www.theses.fr/1991NICE6511.

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13

Escoubas, Pierre. "Alcaloïdes de fourmis identification, toxicité et mode d'action /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37613521n.

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14

Pittaya, Kanchanapakonchai Amnuay Thithapandha. "Effects of vitamin B6 on CC14 toxicities in rats /." abstract, 1986. http://mulinet3.li.mahidol.ac.th/thesis/2529/29E-Pittaya-K.pdf.

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15

Sánchez, González Marta. "Estudi de la toxicitat i biodisponibilitat de l’àcid maslínic." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/283977.

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L’àcid maslínic (2a, 3ß-dihidroxilean-12-ene-28oic) és un triterpè pentacíclic que s’ha aïllat de diferents espècies vegetals, tant medicinals com comestibles, i al qual se li han atribuït efectes beneficiosos per a la salut. A la present memòria s’ha estudiat la toxicitat i la biodisponibilitat d’aquest compost per tal d’aprofundir en el seu coneixement. En primer lloc, s’ha posat a punt una tècnica per determinar l’àcid maslínic a plasma de rata mitjançant una doble extracció líquid-líquid i posterior anàlisi per HPLC-MS. Aquest mètode ha demostrat ser lineal (R>0,997), exacte (<4,82%), sens

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16

Mansour, Hamza. "Toxicité pulmonaire et lymphoïde de l'oxygène normobare études pharmacologiques." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb37599420z.

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17

QUILLASI, VINCENT. "Toxicite des anti-arythmiques de la classe 1c." Lyon 1, 1990. http://www.theses.fr/1990LYO1M034.

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18

Halioua, Bruno. "Toxicite lipidique et oculaire des retinoides de synthese." Nice, 1990. http://www.theses.fr/1990NICE6822.

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19

Bedane, Christophe. "Effets secondaires et toxicite des retinoides de synthese." Limoges, 1988. http://www.theses.fr/1988LIMO0133.

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20

Escoubas, Pierre. "Alcaloides de fourmis : identification, toxicite et mode d'action." Paris 6, 1988. http://www.theses.fr/1988PA066228.

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Les alcaloides synthetises par les fourmis des genres monomorium et solenopsis sont des insecticides de contact. De nouvelles molecules ont ete identifiees et leur mode d'action etudie. La structure chimique particuliere des molecules leur confere une liposolubilite elevee, et leur permet de franchir la barriere epicuticulaire. Ces toxines agissent comme bloquants du systeme nerveux de l'insecte

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21

Huang, Kevin M. "Contribution of organic cation-type transporters to chemotherapy-induced toxicities." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1606768331375801.

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22

Matsubara, Junichi. "Identification of a Predictive Biomarker for Hematologic Toxicities of Gemcitabine." Kyoto University, 2011. http://hdl.handle.net/2433/142054.

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23

Wall, Bradley A. "Exercise as medicine : reversing treatment toxicities in prostate cancer patients." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2013. https://ro.ecu.edu.au/theses/691.

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A common treatment for prostate cancer, which is the most common form of cancer after skin cancer in Australian males, is androgen deprivation therapy (ADT). However, ADT is associated with an array of adverse effects including reduced bone and lean mass, loss of muscle strength, negative change in lipid profile, and increased risk of cardiovascular disease (CVD) as well as diabetes, all of which can compromise physical function and quality of life. Physical exercise has been suggested as a key lifestyle intervention for this group of cancer patients as it has enormous potential to limit and e

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24

DHERS, DOMINIQUE. "Toxicite des pyrethres : etude sur 270 appels recus au centre anti-poisons de toulouse, de janvier 1992 a juin 1994." Toulouse 3, 1994. http://www.theses.fr/1994TOU31118.

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25

DELAFOND, ALAIN. "Risques toxicologiques des amalgames dentaires." PARIS 6, DENTAIRE, 1994. http://www.theses.fr/1994PA06H002.

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26

Robbana-Barnat, Saïda. "Toxicité et pouvoir immunomodulateur de mycotoxines (désoxynivalénol, T-2 toxine)." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb376007996.

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27

BRILLET, GEORGES. "Toxicite renale chronique du cisplatine : etude clinique et experimentale." Reims, 1992. http://www.theses.fr/1992REIMM065.

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28

Turcat-Brines, Carole. "Etude de la toxicite nerveuse peripherique des triaryl-phosphates." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20213.

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29

Ard, Teri A. "The comparative toxicities of filtrates from conventional and alternative bleaching agents." Diss., Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/7008.

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30

Sutton, April E. "Residual toxicities of synergized pyrethrins and methoprene applied as aerosol insecticides." Thesis, Manhattan, Kan. : Kansas State University, 2009. http://hdl.handle.net/2097/2331.

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31

SADEG, NOUREDINE. "Etude toxicopharmacologique et immunotoxicologique de la cyclosporine a et de ses principaux metabolites." Paris 5, 1992. http://www.theses.fr/1992PA05P617.

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32

Joyeux, Michel. "Contribution a l'etude des effets toxiques des sous-produits de la chloration de l'eau." Nancy 1, 1994. http://www.theses.fr/1994NAN11112.

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33

LE, NOIR DE CARLAN HERVE. "Toxicologie des pyralenes : revue de la litterature." Lyon 1, 1989. http://www.theses.fr/1989LYO1M102.

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34

Roux, Vincent. "Toxicite de l'aminotriazole et de l'atrazine : a propos d'une observation." Lille 2, 1990. http://www.theses.fr/1990LIL2M043.

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35

MAREZ, THIERRY. "Consequences cardiaques, respiratoires et genotoxiques en relation avec l'exposition professionnelle au methacrylate de methyle et l 'etude des effets cytotoxiques et genotoxiques in vitro." Lille 2, 1989. http://www.theses.fr/1989LIL2P280.

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36

BLANZAT, ANNIE. "Etat actuel des connaissances sur le cannabis sativa l." Strasbourg 1, 1994. http://www.theses.fr/1994STR15078.

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37

Abad, Fernández Mª Alba. "Pentraxina Neuronal i la toxicitat sinàptica en la malaltia d'Alzheimer, La." Doctoral thesis, Universitat de Barcelona, 2008. http://hdl.handle.net/10803/898.

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TESI:<br/><br/>L'objectiu general del projecte de tesi és estudiar la implicació de la NP1 en el procés de mort neuronal programada i en el dany sinàptic induïts per beta-amiloid en la malaltia d'Alzheimer.<br/><br/>Està descrit que l'acumulació de beta-amiloid juga un paper central en la pèrdua progressiva de sinapsis, el dany neurític i la mort neuronal característiques de la malaltia d'Alzheimer. Els mecanismes mitjançant els quals el pèptid beta-amiloid indueix aquesta neurotoxicitat encara romanen desconeguts.<br/>Ens basem en la hipòtesi de que les proteïnes del programa de mort cel·lula

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38

Riera, Armengol Pau. "Marcadors genètics d'eficàcia i toxicitat en el tractament del càncer colorectal." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/671210.

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El càncer colorectal (CCR) és una neoplàsia molt freqüent que causa una elevada mortalitat arreu del món. Els fàrmacs més utilitzats en el seu maneig són quimioteràpics (fluoropirimidines, oxaliplatí i irinotecan), agents biològics contra el receptor del factor de creixement epidèrmic (fàrmacs anti-EGFR, com el cetuximab i el panitumumab) i antiangiogènics (fàrmacs anti-VEGF, com el bevacizumab i l’aflibercept). Malgrat els avenços produïts en els últims anys, l’efectivitat d’aquests fàrmacs continua essent limitada. A més, cal tenir en compte l’elevat cost i toxicitat de molts d’aquests tract

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39

Shacoori, Valliollah. "Contribution à l'étude du mécanisme de toxicité du maléate de perhexiline." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376099063.

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40

Lelièvre, Hélène. "Le Diéthylstilboestrol toxicité, métabolisme et mise au point d'un enzymo-immunodosage /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376151738.

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41

PICARD, PASCAL. "Toxicite du midazolam injecte par voie intrathecale chez le rat." Clermont-Ferrand 1, 1989. http://www.theses.fr/1989CLF13801.

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42

COSTA, BRIGITTE. "La toxicite cardiaque des anthracyclines et des autres traitements anticancereux." Reims, 1994. http://www.theses.fr/1994REIMM009.

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43

HAYEM, GILLES. "Etude experimentale de la toxicite des fluoroquinolones sur l'appareil locomoteur." Paris 7, 1997. http://www.theses.fr/1997PA077039.

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Pour mieux comprendre la toxicite des quinolones sur les articulations et les tendons, nous avons concu deux types de modeles experimentaux utilisant des cultures cellulaires de chondrocytes articulaires et de tenocytes de lapin. Ces cellules ont ete traitees, in vivo et surtout in vitro, par differentes quinolones, fluorees ou non, a des doses et pendant des durees variables. Une analyse biochimique et cytofluorometrique, centree sur le comportement du secteur mitochondrial et du systeme oxydatif cellulaires, a permis d'aboutir aux conclusions suivantes : les quinolones stimulent tres precoce

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44

Robbana-Barnat, Saïda. "Toxicite et pouvoir immunomodulateur de mycotoxines (desoxynivalenol, t-2 toxine)." Paris 6, 1986. http://www.theses.fr/1986PA066597.

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45

Danjuma, M. I. "Determinants of anti-retroviral therapy drug-related toxicities in HIV positive patients." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3011379/.

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Antiretroviral therapy (ART) drugs have increasingly been shown to contribute significantly to the morbidity of HIV positive patients exposed to them. This is more so with increasing survival of HIV patients since the introduction of ART. Individual ART drugs have been associated with specific organ related toxicities and clinical toxicity syndromes, such as Tenofovir disoproxil fumarate (TDF) association with risk of kidney injury. The pattern, pathogenesis, as well as key genetic and non-genetic determinants of some these clinical ART drug-related toxicity syndromes remains uncertain. This t

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46

Okeson, Carl D. "In-Vitro Analysis of the Respiratory Toxicities of Fossil Fuel Combustion Ashes." Diss., The University of Arizona, 2006. http://hdl.handle.net/10150/194225.

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Epidemiological studies have linked exposure to elevated levels of airborne particulate matter with increased incidences of several types of respiratory disease, hospital admissions and morbidity. Millions of tons of airborne particulate matter are generated and released into the atmosphere each year. However, particulate matter resulting from the combustion of fuel oil and coal are of particular concern, because they are generally composed of small particles that can easily penetrate deep into the lungs, and can contain significant concentrations of toxic transition metals, such as zinc, iron

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47

Wang, Bingxuan. "Mechanistic studies of the toxicities of the aryl hydrocarbon receptor agonist PCB126." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/2786.

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PCB126 is the most potent agonist of the aryl hydrocarbon receptor (AhR) in the whole family of chlorinated biphenyls (PCBs), a class of persistent organic pollutants that are classified as probable human carcinogens. It exerts systematic toxicities in animals mainly through the AhR pathway and generates cellular oxidative stress which might damage cellular macromolecules. The goal of this thesis is to elucidate the mechanisms of PCB126 toxicity in the aspect of AhR-related oxidative stress. Reactive superoxide radicals could be generated as the result of electron leakage in the catalytic cycl

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48

Donatiello, Cosima. "La toxicité cardiaque des anthracyclines dans le traitement des tumeurs de l'enfant /." Genève : [s.n.], 2002. http://www.unige.ch/cyberdocuments/theses2002/DonatielloC/these.pdf.

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49

Doran, Dominic Anthony. "The role of exercise in the management of protease inhibitor related glucose toxicities." Thesis, Liverpool John Moores University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502751.

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50

Shacoori, Valliollah. "Contribution a l'etude du mecanisme de toxicite du maleate de perhexiline." Rennes 1, 1987. http://www.theses.fr/1987REN10101.

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