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Journal articles on the topic 'Toxicity tests'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Spielmann, Horst. "Alternative toxicity tests." Nature 357, no. 6378 (1992): 432. http://dx.doi.org/10.1038/357432a0.

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2

ERICKSON, BRITT E. "MODERNIZING TOXICITY TESTS." Chemical & Engineering News Archive 89, no. 29 (2011): 25–26. http://dx.doi.org/10.1021/cen-v089n029.p025.

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3

Gillis, Anna Maria. "Toxicity Tests Minus Animals?" BioScience 43, no. 3 (1993): 137–40. http://dx.doi.org/10.2307/1312016.

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4

Toussaint, Margaret W., Tommy R. Shedd, William H. van der Schalie, and Gerald R. Leather. "A comparison of standard acute toxicity tests with rapid-screening toxicity tests." Environmental Toxicology and Chemistry 14, no. 5 (1995): 907–15. http://dx.doi.org/10.1002/etc.5620140524.

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5

de March, B. G. E. "Mixture Toxicity Indices in acute lethal toxicity tests." Archives of Environmental Contamination and Toxicology 16, no. 1 (1987): 33–37. http://dx.doi.org/10.1007/bf01055357.

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6

UMEDA, MAKOTO. "Toxicity Tests Using Cultured Cells." Eisei kagaku 42, no. 6 (1996): 443–52. http://dx.doi.org/10.1248/jhs1956.42.443.

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7

Snell, Terry W., Brian D. Moffat, Colin Janssen, and Guido Persoone. "Acute toxicity tests using rotifers." Ecotoxicology and Environmental Safety 21, no. 3 (1991): 308–17. http://dx.doi.org/10.1016/0147-6513(91)90070-6.

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8

McGreer, E. R. "Sediment toxicity tests: research needs." Aquatic Toxicology 11, no. 3-4 (1988): 410. http://dx.doi.org/10.1016/0166-445x(88)90108-7.

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9

Janssen, C. R., G. Persoone, and T. W. Snell. "Cyst-based toxicity tests. VIII. Short-chronic toxicity tests with the freshwater rotifer Brachionus calyciflorus." Aquatic Toxicology 28, no. 3-4 (1994): 243–58. http://dx.doi.org/10.1016/0166-445x(94)90036-1.

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10

Bailer, A. John, and James T. Oris. "MODELING REPRODUCTIVE TOXICITY IN CERIODAPHNIA TESTS." Environmental Toxicology and Chemistry 12, no. 4 (1993): 787. http://dx.doi.org/10.1897/1552-8618(1993)12[787:mrtict]2.0.co;2.

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11

Green, T. "Changes in metabolism during toxicity tests." Xenobiotica 20, no. 11 (1990): 1233–40. http://dx.doi.org/10.3109/00498259009046840.

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12

Sklarew, M. "Toxicity tests in animals: alternative models." Environmental Health Perspectives 101, no. 4 (1993): 288–91. http://dx.doi.org/10.1289/ehp.93101288.

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13

Lambré, Claude R., Michaela Aufderheide, Robert E. Bolton, et al. "In Vitro Tests for Respiratory Toxicity." Alternatives to Laboratory Animals 24, no. 5 (1996): 671–81. http://dx.doi.org/10.1177/026119299602400506.

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14

Brown, V. K. "Predictive Acute Toxicity Tests With Pesticides." Acta Pharmacologica et Toxicologica 52 (March 13, 2009): 247–62. http://dx.doi.org/10.1111/j.1600-0773.1983.tb02693.x.

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15

Welscher, U., M. Michailov, S. Magour, E. Neu, C. Hahnel, and D. G. Weiss. "Toxicity tests on urogenital tract preparations." Pharmacological Research 31 (January 1995): 142. http://dx.doi.org/10.1016/1043-6618(95)86829-1.

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16

Sullivan, F. M. "Reproductive Toxicity Tests: Retrospect and Prospect." Human Toxicology 7, no. 5 (1988): 423–27. http://dx.doi.org/10.1177/096032718800700507.

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1 The design of the classical three segment reproductive test for new drugs is described and the relative merits of the USA/EEC and the Japanese guidelines are discussed. 2 The importance of pharmacokinetic studies in the interpretation of teratology studies and extrapolation to humans is mentioned in relation to caffeine, sodium valproate and cyclophosphamide. 3 Changing ideas on the design of multi-generation studies are reviewed. 4 Recent developments in the fields of behavioural teratology, chemicals in breast milk and transplacental carcinogenesis are described.

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17

FORD, JASON. "Nanotech device enables onsite toxicity tests." Engineer 302, no. 7927 (2021): 8. http://dx.doi.org/10.12968/s0013-7758(22)90008-x.

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18

KAISER, MARK S., and SUSAN E. FINGER. "A MODEL FOR FIELD TOXICITY TESTS." Environmetrics 7, no. 2 (1996): 215–29. http://dx.doi.org/10.1002/(sici)1099-095x(199603)7:2<215::aid-env206>3.0.co;2-b.

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19

Dearden, John C. "Rodent LD50 Tests." International Journal of Quantitative Structure-Property Relationships 5, no. 3 (2020): 1–5. http://dx.doi.org/10.4018/ijqspr.2020070101.

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Rodent LD50 values have been used for almost a century as a measure of potential human toxicity from drugs and other chemicals. However, they have been found not, on the whole, to be good models for human toxicity. One reason for this could be the often-high variability of LD50 values. It has recently been shown that by using median LD50 values, very good correlations have been found with human lethal dosages. Bearing in mind the millions of rodent lives sacrificed, many with no good reason, it is proposed that some reparation could be made by more investigations using median values of already

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20

Rentz, Neil, and Mark Hanson. "Duckweed Toxicity Tests ARE Appropriate For ERA." Integrated Environmental Assessment and Management 5, no. 2 (2009): 350. http://dx.doi.org/10.1897/1551-3793-5.3.350.

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21

Festing, Michael. "Experimental design, genetics and animal toxicity tests." Significance 4, no. 1 (2007): 37–40. http://dx.doi.org/10.1111/j.1740-9713.2007.00220.x.

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22

Karstadt, Myra. "Inadequate Toxicity Tests of Food Additive Acesulfame." International Journal of Occupational and Environmental Health 16, no. 1 (2010): 89–96. http://dx.doi.org/10.1179/oeh.2010.16.1.89.

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23

Spurny, K. R. "Fibrous aerosols: physical and chemical toxicity tests." Journal of Aerosol Science 30 (September 1999): S707—S708. http://dx.doi.org/10.1016/s0021-8502(99)80364-4.

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24

Bownik, Adam. "Physiological endpoints in daphnid acute toxicity tests." Science of The Total Environment 700 (January 2020): 134400. http://dx.doi.org/10.1016/j.scitotenv.2019.134400.

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25

ZURER, PAMELA. "CFC SUBSTITUTES: Candidates pass early toxicity tests." Chemical & Engineering News 67, no. 41 (1989): 4. http://dx.doi.org/10.1021/cen-v067n041.p004.

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26

Kooijman, S. A. L. M., and J. J. M. Bedaux. "Analysis of toxicity tests on fish growth." Water Research 30, no. 7 (1996): 1633–44. http://dx.doi.org/10.1016/0043-1354(96)00057-7.

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27

Chapman, Peter M. "Do sediment toxicity tests require field validation?" Environmental Toxicology and Chemistry 14, no. 9 (1995): 1451–53. http://dx.doi.org/10.1002/etc.5620140901.

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28

Grothe, Donald R., and Daniel E. Johnson. "Bacterial interference in whole-effluent toxicity tests." Environmental Toxicology and Chemistry 15, no. 5 (1996): 761–64. http://dx.doi.org/10.1002/etc.5620150523.

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29

Micevska, Tina, and Stuart Simpson. "Modifying tie methods to demonstrate dietary toxicity in whole-sediment toxicity tests." Integrated Environmental Assessment and Management 4, no. 3 (2008): 371–72. http://dx.doi.org/10.1002/ieam.5630040314.

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30

Slabbert, J. L., and E. A. Venter. "Biological assays for aquatic toxicity testing." Water Science and Technology 39, no. 10-11 (1999): 367–73. http://dx.doi.org/10.2166/wst.1999.0684.

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A number of aquatic toxicity tests have been established for South African use, which include fish and Daphnia lethality tests, microbiotests, and short-term chronic tests. Studies on effluents and surface waters showed that all the tests have a viable role to play in water quality management. The most advantageous use of the tests is in battery form, so that tests can complement each other. The fish and Daphnia lethality tests, and algal growth inhibition test are recommended for regulatory and management purposes of effluents. If receiving water is used for drinking water purposes, the Ames

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31

Hao, Oliver J., Shin Chien-Jen, Lin Cheng-Fang, Jeng Fu-Tien, and Chen Zen-Chyuan. "Use of microtox tests for screening industrial wastewater toxicity." Water Science and Technology 34, no. 10 (1996): 43–50. http://dx.doi.org/10.2166/wst.1996.0237.

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Conventional parameters such as chemical oxygen demand and suspended solids may not detect toxic compounds present in a variety of industrial wastewaters and treated wastes. Thus, the presence of toxicity in many industrial wastes presents a significant impact on biological wastewater treatment, and exerts adverse effects on receiving waters. Because of their easy technique and rapid turnaround results, the Microtox tests were used in this study to pinpoint unusual wastewaters, evaluate the toxicity reduction through activated sludge processes, observe the impact of excessive chemical addition

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32

Clemedson, Cecilia, Elisabeth McFarlane-Abdulla, Marianne Andersson, et al. "MEIC Evaluation of Acute Systemic Toxicity." Alternatives to Laboratory Animals 24, no. 1_part_1 (1996): 251–72. http://dx.doi.org/10.1177/026119299602400102.1.

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The multicentre evaluation of in vitro cytotoxicity (MEIC) study is a programme designed to evaluate the relevance of in vitro toxicity tests for predicting human toxicity, and is organised by the Scandinavian Society for Cell Toxicology. The project started in 1989 and is scheduled to be finished by June 1996. MEIC is a voluntary effort by international laboratories to test the same 50 reference chemicals in their own in vitro toxicity systems. At present, 31 laboratories have submitted results for the first 30 reference chemicals from a total of 68 in vitro cytotoxicity tests. In the definit

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33

Jop, Krzysztof M., Thomas F. Parkerton, John H. Rodgers, Kenneth L. Dickson, and Philip B. Dorn. "Comparative toxicity and speciation of two hexavalent chromium salts in acute toxicity tests." Environmental Toxicology and Chemistry 6, no. 9 (1987): 697–703. http://dx.doi.org/10.1002/etc.5620060907.

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34

Torres Lozada, Patricia, Yazmin Carabalí Rivera, and Luz Edith Barba Ho. "Evaluation of toxicity from leachate lagoons sediments, using the toxicity leaching procedure - TCLP and acute toxicity tests." DYNA 86, no. 208 (2019): 192–98. http://dx.doi.org/10.15446/dyna.v86n208.75348.

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Landfills have been the most used alternative for final municipal solid wastes disposal, however, this system is the responsible of contamination problems associated with the generation of leachates, sediments and toxic gasses emissions. The sediments occur by the organic and inorganic matter precipitation from leachates dumped in retention lagoons, which can present toxic characteristics than affect the environment. The aim of this work was to evaluate the potential toxicity of leachates from a municipal landfill, using the TCLP procedure and acute toxicity assays with Daphnia pulex and Poeci

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35

van, Gestel Cornelis A.M., Susana Loureiro, and Promoz Zidar. "Terrestrial isopods as model organisms in soil ecotoxicology: a review." ZooKeys 801 (December 3, 2018): 127–62. https://doi.org/10.3897/zookeys.801.21970.

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Isopods play an important role in the decomposition of leaf litter and therefore are making a significant contribution to nutrient cycling and soil ecosystem services. As a consequence, isopods are relevant models in soil ecotoxicology, both in laboratory toxicity tests and in field monitoring and bioindication studies. This paper aims at reviewing the use of isopods as test organisms in soil ecotoxicology. It provides an overview of the use of isopods in laboratory toxicity tests, with special focus on comparing different exposure methods, test durations, and ecotoxicological endpoints. A bri

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36

Aydιn, Ahmet, Göknur Aktay, and Erdem Yesilada. "A Guidance Manual for the Toxicity Assessment of Traditional Herbal Medicines." Natural Product Communications 11, no. 11 (2016): 1934578X1601101. http://dx.doi.org/10.1177/1934578x1601101131.

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Herbal remedies have been used for thousands of years in worldwide traditional medicines for their potential health benefits. Although they are generally presumed safe unless a significant risk has been identified in humans, increasing number of case reports notify acute or chronic intoxications resulting from their use. This study aims to produce a scientific guide for the evaluation of traditional herbal medicines (THMs) in terms of their toxicity risks based on the published regulatory documents. For this purpose recommended in vitro and in vivo toxicity tests on medicinal products for huma

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37

Haq, Mohammad Inamul, Joanna Nixon, and Adrian J. Stanley. "Imatinib and liver toxicity." BMJ Case Reports 11, no. 1 (2018): e226740. http://dx.doi.org/10.1136/bcr-2018-226740.

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Imatinib is a specific tyrosine kinase inhibitor which has been approved for the treatment of Philadelphia chromosome-positive chronic myeloid leukaemia and c-KIT (CD117)-positive gastrointestinal stromal tumours. It has been associated with hepatotoxicity ranging from abnormal liver function tests to acute liver failure along with chronic hepatitis B reactivation. We report the case of a patient who was started on adjuvant treatment with imatinib following resection of a primary gastrointestinal stromal cell tumour of jejunum and developed severe hepatotoxicity. There was no history of risk f

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38

Hosomi, Masaaki, and Hidehiro Kaneko. "Assessment of Hazardous Wastes Using Acute Toxicity Tests." Waste Management Research 9, no. 5 (1998): 384–93. http://dx.doi.org/10.3985/wmr.9.384.

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39

Maloney, Dennis. "Toxicity Tests in Animals: Extrapolating to Human Risks." Environmental Health Perspectives 101, no. 5 (1993): 396. http://dx.doi.org/10.2307/3431894.

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40

Zeiger, Errol. "Strategies for the Use of Genetic Toxicity Tests." Drug Metabolism Reviews 22, no. 6-8 (1990): 765–75. http://dx.doi.org/10.3109/03602539008991467.

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41

Park, Jin Hwa, and Yong Woo Yl. "Toxicity Screening Tests for Wastewater Treatment Plants – I." Key Engineering Materials 277-279 (January 2005): 559–68. http://dx.doi.org/10.4028/www.scientific.net/kem.277-279.559.

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Toxicity screening tests using the Reserve Electron Transfer (RET) and Electron Transfer (ETr) assays were performed with five wastewater samples amended with trickling filter (TF) or activated sludge (AS) biomass. In the case of untreated samples, Home Life domestic wastewater (HLD/W) showed the lowest inhibition, followed by domestic sewage (DS), hospital wastewater (H/W), East Straus wastewater (ES/W), and Mills wastewater (M/W) from both ETr and RET assays. After 12 hours of treatment at 20°C, DS with AS biomass had the lowest % inhibition from the RET assay, followed by DS with TF, HLD/W

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42

&NA;. "Toxicity tests unnecessary for HIV in developing world." Reactions Weekly &NA;, no. 1284 (2010): 3. http://dx.doi.org/10.2165/00128415-201012840-00008.

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43

Poštulková, Eva, and Radovan Kopp. "Guanicid and PHMG Toxicity Tests on Aquatic Organisms." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 64, no. 1 (2016): 129–34. http://dx.doi.org/10.11118/actaun201664010129.

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The emergence and development of new algicidal products is caused by the ever increasing popularity of garden ponds as well as the use of these products in the fisheries sector, especially for disposal of cyanobacteria and algae. Most frequent means of combating cyanobacteria and algae are applications of algicidal substances. Newly developed algaecides include Guanicid and polyhexamethylene guanidine hydrochloride (PHMG). The aim of the study was to identify toxic effects of Guanicid and PHMG on zebrafish (Danio rerio) and green algae (Desmodesmus communis). We determined the acute toxicity i

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44

Simonsen, Susanne, and Øjvind Moestrup. "Toxicity tests in eight species of Chrysochromulina (Haptophyta)." Canadian Journal of Botany 75, no. 1 (1997): 129–36. http://dx.doi.org/10.1139/b97-015.

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Blooms of the marine flagellate Chrysochromulina have resulted in mortality of marine organisms in Scandinavian waters, including fish in aquaculture. Eight species of Chrysochromulina, namely C. apheles, C. brevifilum, C. ericina, C. hirta, C. leadbeateri, C. parva, C. polylepis, and C. simplex, isolated into unialgal culture, were examined for haemolytic activity and toxicity to the brine shrimp, Artemia salina. Haemolytic fractions were obtained from all species, but only C. polylepis cells were toxic to Artemia. Thin-layer chromatography (TLC) analysis in chloroform –methanol–water (75:25:

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45

Eriksson, Eva, Anders Baun, Mogens Henze, and Anna Ledin. "Phytotoxicity of grey wastewater evaluated by toxicity tests." Urban Water Journal 3, no. 1 (2006): 13–20. http://dx.doi.org/10.1080/15730620600578645.

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46

Scanu, M., L. Mancuso, and G. Cao. "Human mesenchymal stem cells for acute toxicity tests." Toxicology Letters 205 (August 2011): S175. http://dx.doi.org/10.1016/j.toxlet.2011.05.609.

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47

Cukras, Catherine, Nancy Huynh, Susan Vitale, Wai T. Wong, Fredrick L. Ferris, and Paul A. Sieving. "Subjective and Objective Screening Tests for Hydroxychloroquine Toxicity." Ophthalmology 122, no. 2 (2015): 356–66. http://dx.doi.org/10.1016/j.ophtha.2014.07.056.

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48

Jop, Krzysztof M., John H. Rodgers, Edmund E. Price, and Kenneth L. Dickson. "Renewal device for test solutions inDaphnia toxicity tests." Bulletin of Environmental Contamination and Toxicology 36, no. 1 (1986): 95–100. http://dx.doi.org/10.1007/bf01623480.

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49

Seidel, Florian. "Highlight report: Stem cell-based developmental toxicity tests." Archives of Toxicology 92, no. 12 (2018): 3609–10. http://dx.doi.org/10.1007/s00204-018-2357-y.

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50

Jayne Haynes, G., Arthur J. Stewart, and Bret C. Harvey. "Gender-dependent problems in toxicity tests withCeriodaphnia dubia." Bulletin of Environmental Contamination and Toxicology 43, no. 2 (1989): 271–79. http://dx.doi.org/10.1007/bf01701758.

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