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Journal articles on the topic 'Toxicology'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Hayes, A. Wallace, and Darlene Dixon. "Cornerstones of Toxicology." Toxicologic Pathology 45, no. 1 (2017): 57–63. http://dx.doi.org/10.1177/0192623316675768.

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The 35th Annual Society of Toxicologic Pathology Symposium, held in June 2016 in San Diego, California, focused on “The Basis and Relevance of Variation in Toxicologic Responses.” In order to review the basic tenants of toxicology, a “broad brush” interactive talk that gave an overview of the Cornerstones of Toxicology was presented. The presentation focused on the historical milestones and perspectives of toxicology and through many scientific graphs, data, and real-life examples covered the three basic principles of toxicology that can be summarized, as dose matters (as does timing), people

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2

BABIŃSKA, IZABELLA, JÓZEF SZAREK, MARIUSZ Z. FELSMANN, and ANDRZEJ DZIKOWSKI. "Scientific toxicology societies in Europe." Medycyna Weterynaryjna 74, no. 1 (2018): 5981–2018. http://dx.doi.org/10.21521/mw.5981.

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With the development of toxicology as a science, the second half of the 20th century saw the establishment of scientific societies, such as the International Society of Ecotoxicology and Environmental Safety (SECOTOX), the Federation of European Toxicologists and European Societies of Toxicology (EUROTOX), the Polish Society of Toxicology, and the European Society of Toxicologic Pathology (ESTP). This study describes their development, organizational structure and mission. The scope of their interest, in addition to toxicology, also includes ecotoxicology, which protects the natural environmen

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3

Hukkanen, Renee R., Noel Dybdal, Niraj Tripathi, Patricia V. Turner, and Sean P. Troth. "Scientific and Regulatory Policy Committee Points to Consider*: The Toxicologic Pathologist’s Role in the 3Rs." Toxicologic Pathology 47, no. 7 (2019): 789–98. http://dx.doi.org/10.1177/0192623319859261.

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Pathologists are trained medical professionals with special expertise in diagnostics, research, and pathophysiology. In these roles, pathologists are well qualified and positioned to engage in conversations about animal use replacement, reduction, and refinement (3Rs), thereby championing the guiding principles of the 3Rs. In particular, toxicology or nonclinical safety assessment is an important area where the discipline of toxicologic pathology can have a critical role in adopting 3Rs principles. As such, a working group of the Society of Toxicologic Pathology Scientific and Regulatory Polic

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4

Cohen, Samuel M., Wanda M. Haschek-Hock, and Carl Alden. "Obituary: Dr Gordon Charles Hard (1931-2021)." Toxicologic Pathology 50, no. 2 (2022): 164–65. http://dx.doi.org/10.1177/01926233211068853.

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Dr Gordon Hard, of Tairua, New Zealand, a preeminent international toxicology thought leader and international consultant in toxicologic pathology of the kidney, passed on November 22, 2021. He was a key player in shaping and developing the global field of toxicologic pathology and the role of toxicologic pathology in risk assessment of environmental chemicals and pharmaceuticals.

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5

Bolon (Chair), Brad, Erio Barale-Thomas, Alys Bradley, et al. "International Recommendations for Training Future Toxicologic Pathologists Participating in Regulatory-type, Nonclinical Toxicity Studies." Toxicologic Pathology 38, no. 6 (2010): 984–92. http://dx.doi.org/10.1177/0192623310378137.

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The International Federation of Societies of Toxicologic Pathologists (IFSTP) proposes a common global framework for training future toxicologic pathologists who will support regulatory-type, nonclinical toxicology studies. Optimally, trainees should undertake a scientific curriculum of at least five years at an accredited institution leading to a clinical degree (veterinary medicine or medicine). Trainees should then obtain four or more years of intensive pathology practice during a residency and/or on-the-job “apprenticeship,” at least two years of which must be focused on regulatory-type to

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6

Maronpot, Robert R., Abraham Nyska, Sean P. Troth, et al. "Regulatory Forum Opinion Piece*: Imaging Applications in Toxicologic Pathology—Recommendations for Use in Regulated Nonclinical Toxicity Studies." Toxicologic Pathology 45, no. 4 (2017): 444–71. http://dx.doi.org/10.1177/0192623317710014.

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Available imaging systems for use in preclinical toxicology studies increasingly show utility as important tools in the toxicologic pathologist’s armamentarium, permit longitudinal evaluation of functional and morphological changes in tissues, and provide important information such as organ and lesion volume not obtained by conventional toxicology study parameters. Representative examples of practical imaging applications in toxicology research and preclinical studies are presented for ultrasound, positron emission tomography/single-photon emission computed tomography, optical, magnetic resona

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7

Troth, Sean P., Nancy E. Everds, William Siska, Brian Knight, Martin Lamb, and Julie Hutt. "Scientific and Regulatory Policy Committee Points to Consider: Data Visualization for Clinical and Anatomic Pathologists." Toxicologic Pathology 46, no. 5 (2018): 476–87. http://dx.doi.org/10.1177/0192623318778733.

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Assessment and communication of toxicology data are fundamental components of the work performed by veterinary anatomic and clinical pathologists involved in toxicology research. In recent years, there has been an evolution in the number and variety of software tools designed to facilitate the evaluation and presentation of toxicity study data. A working group of the Society of Toxicologic Pathology Scientific and Regulatory Policy Committee reviewed existing and emerging visualization technologies. This Points to Consider article reviews some of the currently available data visualization opti

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8

Bhat, Sagar S., and Srinivasa Gopala Rao. "Toxicology-the blind spot." Asian Pacific Journal of Health Sciences 5, no. 3 (2018): 225–32. http://dx.doi.org/10.21276/apjhs.2018.5.3.31.

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9

Hobson, David W., Stephen M. Roberts, Anna A. Shvedova, David B. Warheit, Georgia K. Hinkley, and Robin C. Guy. "Applied Nanotoxicology." International Journal of Toxicology 35, no. 1 (2016): 5–16. http://dx.doi.org/10.1177/1091581816628484.

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Nanomaterials, including nanoparticles and nanoobjects, are being incorporated into everyday products at an increasing rate. These products include consumer products of interest to toxicologists such as pharmaceuticals, cosmetics, food, food packaging, household products, and so on. The manufacturing of products containing or utilizing nanomaterials in their composition may also present potential toxicologic concerns in the workplace. The molecular complexity and composition of these nanomaterials are ever increasing, and the means and methods being applied to characterize and perform useful t

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10

Lamb, J. C., M. D. Ross, and R. E. Chapin. "Experimental Methods for Studying Male Reproductive Function in Standard Toxicology Studies." Journal of the American College of Toxicology 5, no. 4 (1986): 225–34. http://dx.doi.org/10.3109/10915818609140747.

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Indicators of insult to the male reproductive system can be incorporated into standard toxicology studies so that the assessment of reproductive toxicity does not interfere with the general toxicologic evaluation. This can include assessment of testicular spermatids, or sperm from the epididymis, or vas deferens, or assessment of semen collected from the female reproductive tract postcoitally. Endpoints evaluated may include sperm count, motility, or sperm head morphology. Testicular morphology also may be evaluated by various improved histologic techniques. For example, when testes are immers

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11

Rico Martínez, Roberto. "An Introduction to Aquatic Toxicology [Introducción a la Toxicología acuática]." Investigación y Ciencia de la Universidad Autónoma de Aguascalientes, no. 72 (November 29, 2017): 131–32. http://dx.doi.org/10.33064/iycuaa201772231.

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12

Kuper, C. Frieke, and Maarten C. Bosland. "Victor Feron, A life dedicated to toxicology and toxicologic pathology." Food and Chemical Toxicology 125 (March 2019): 438. http://dx.doi.org/10.1016/j.fct.2019.01.006.

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13

Dagli, Maria L. Z., Arun Pandiri, Jeff Wolf, Sibylle Groeters, and Wanda M. Haschek-Hock. "Global Perspective on Careers in Environmental Toxicologic Pathology: The 2019 Society of Toxicologic Pathology Annual Symposium Lunchtime Career Development Session." Toxicologic Pathology 47, no. 8 (2019): 1088–95. http://dx.doi.org/10.1177/0192623319877859.

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A wide range of career options is available globally in the environmental toxicologic pathology (ETP) arena including academia, government, contract research organizations, and the agrichemical/chemical industry. This small and specialized subset of toxicologic pathologists addresses the effects of contaminants and pollutants on human, animal, and ecological health (One Health). Veterinary students and pathology trainees are primarily exposed to diagnostic pathology and often have limited exposure to toxicologic pathology and even less so to the issues and opportunities in environmental toxico

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14

Zimmerman, Janice L. "Toxicology." Critical Care Clinics 37, no. 3 (2021): i. http://dx.doi.org/10.1016/s0749-0704(21)00029-4.

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15

Mote, Pat. "Toxicology." American Biology Teacher 65, no. 9 (2003): 714–15. http://dx.doi.org/10.2307/4451599.

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16

Zurita, Antonio Zarzuelo. "Toxicology." Pharmaceuticals, Policy and Law 17, no. 1,2 (2015): 101–16. http://dx.doi.org/10.3233/ppl-140404.

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17

Baars, Bert-Jan. "Toxicology." Land Contamination & Reclamation 14, no. 4 (2006): 775–91. http://dx.doi.org/10.2462/09670513.696.

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18

Tabatabai, M. A. "Toxicology." Journal of Environmental Quality 19, no. 2 (1990): 349–50. http://dx.doi.org/10.2134/jeq1990.00472425001900020026x.

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19

Editors, The. "Toxicology." Emergency Care Journal 6, no. 4 (2010): 30. http://dx.doi.org/10.4081/ecj.2010.4.30.

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20

Poppenga, Robert H., and Petra A. Volmer. "Toxicology." Veterinary Clinics of North America: Small Animal Practice 32, no. 2 (2002): 307–8. http://dx.doi.org/10.1016/s0195-5616(01)00002-x.

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21

Cicmanec, J. L. "Toxicology." Toxicology 119, no. 3 (1997): 239. http://dx.doi.org/10.1016/s0300-483x(97)00051-6.

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22

Warshawsky, David, William Barkley, Marian L. Miller, Kathy Ladow, and anastasia Andringa. "Toxicology." Toxicology 96, no. 3 (1995): 239–40. http://dx.doi.org/10.1016/s0300-483x(99)80002-x.

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23

Ensley, Steve, and Timothy J. Evans. "Toxicology." Veterinary Clinics of North America: Food Animal Practice 36, no. 3 (2020): i. http://dx.doi.org/10.1016/s0749-0720(20)30063-3.

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24

Adoga, GI. "Toxicology." Biochemical Education 13, no. 1 (1985): 43. http://dx.doi.org/10.1016/0307-4412(85)90152-9.

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25

Miller, Anita C. K., Lori D. Dwyer-Nield, and Alvin M. Malkinson. "Toxicology." Toxicology 103, no. 1 (1995): 75. http://dx.doi.org/10.1016/0300-483x(95)99371-i.

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26

Lodge, James P. "Toxicology." Atmospheric Environment (1967) 23, no. 10 (1989): 2339. http://dx.doi.org/10.1016/0004-6981(89)90203-5.

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27

Netter, K. J. "Toxicology." Toxicology 61, no. 2 (1990): 212–13. http://dx.doi.org/10.1016/0300-483x(90)90024-b.

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28

Oehme, Frederick W. "Toxicology." Toxicology Letters 87, no. 2-3 (1996): 167–68. http://dx.doi.org/10.1016/0378-4274(96)03769-1.

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29

Fawcett, H. H. "Toxicology." Journal of Hazardous Materials 22, no. 3 (1989): 417. http://dx.doi.org/10.1016/0304-3894(89)80011-1.

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30

Kruse, James A. "Toxicology." Critical Care Clinics 28, no. 4 (2012): xi—xii. http://dx.doi.org/10.1016/j.ccc.2012.08.001.

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31

WADA, OSAMU. "ECO-BIO-TOXICOLOGY AND PREVENTIVE TOXICOLOGY." Journal of Toxicological Sciences 16, SupplementII (1991): 3–12. http://dx.doi.org/10.2131/jts.16.supplementii_3.

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32

Netter, K. J. "Reproductive toxicology (target organ toxicology series)." Toxicology 38, no. 2 (1986): 249–50. http://dx.doi.org/10.1016/0300-483x(86)90126-5.

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33

Morais, Rutiléa Mendes de, Márcia Martins Ornelas, Lucas Da Conceição Santos, and Benedito Gonçalves Eugenio. "O Conhecimento do Conteúdo de Licenciandas de Pedagogia Sobre as Plantas Medicinais e sua Toxicologia." Revista de Ensino, Educação e Ciências Humanas 24, no. 3 (2023): 462–67. http://dx.doi.org/10.17921/2447-8733.2023v24n3p462-467.

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Este artigo apresenta os resultados de uma pesquisa que objetivou compreender quais os conhecimentos que as licenciandas do curso de Pedagogia da Universidade Estadual do Sudoeste da Bahia (UESB) têm sobre o conteúdo das plantas medicinais e a toxicologia das plantas medicinais. Para obtenção dos dados, contamos com questionários e entrevista semiestruturada por meio do CoRe (Representação do Conteúdo). Para o processo de análise consideramos três categorias, a saber: 1) Conhecimentos das licenciandas sobre as plantas medicinais; 2) Conhecimentos das licenciandas sobre a intoxicação por planta

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34

Harrill, Alison H., Jonathan G. Moggs, Karissa K. Adkins, Hellmut G. Augustin, Robert C. Johnson, and Michael W. Leach. "A Synopsis of the “Influence of Epigenetics, Genetics, and Immunology” Session Part A at the 35th Annual Society of Toxicologic Pathology Symposium." Toxicologic Pathology 45, no. 1 (2016): 114–18. http://dx.doi.org/10.1177/0192623316670781.

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The overarching theme of the 2016 Society of Toxicology Pathology’s Annual Symposium was “The Basis and Relevance of Variation in Toxicologic Responses.” Session 4 focused on genetic variation as a potential source for variability in toxicologic responses within nonclinical toxicity studies and further explored how knowledge of genetic traits might enable targeted prospective and retrospective studies in drug development and human health risk assessment. In this session, the influence of both genetic sequence variation and epigenetic modifications on toxicologic responses and their implication

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35

Patočka, Jiří, Zdeněk Hon, Petr Procházka, and Kamil Kuča. "Toxicology and environmental toxicology of herbicide triclopyr." Kontakt 13, no. 2 (2011): 242–49. http://dx.doi.org/10.32725/kont.2011.029.

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36

Boué, S., B. Hardy, W. Hayes, et al. "Sharing systems toxicology data for inhalation toxicology." Toxicology Letters 259 (October 2016): S141—S142. http://dx.doi.org/10.1016/j.toxlet.2016.07.598.

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37

Manzetti, Sergio. "Quantum toxicology—A potential perspective in toxicology?" Toxicology 288, no. 1-3 (2011): 56–57. http://dx.doi.org/10.1016/j.tox.2011.06.015.

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38

Gussow, Leon. "Toxicology Rounds: Kitchen Toxicology: Nutmeg (the Hallucinogen)." Emergency Medicine News 33, no. 5 (2011): 16. http://dx.doi.org/10.1097/01.eem.0000398222.48791.3d.

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39

Christian, Mildred S. "History of the American College of Toxicology (ACT)." International Journal of Toxicology 23, no. 5 (2004): 285–99. http://dx.doi.org/10.1080/10915810490517054.

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This manuscript is one of two written to celebrate the 25th Anniversary of the American College of Toxicology (ACT). This history of ACT describes its evolution from an entrepreneurial, risk taking model to a conservative business model, fully accepted in the scientific community. ACT started with a small group of scientists who were dissatisfied with the relatively narrow approach to full membership then taken by the Society of Toxicology (SOT). They were excited by new research and collaborative opportunities resulting from an enhanced public awareness of the impact of chemicals on the envir

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40

Petkov, Daniel, Daniel J. Patrick, Petrina Rogerson, et al. "Idiopathic Aneurysms of the Ascending Aorta in the Mouse and Rat." Toxicologic Pathology 50, no. 1 (2021): 4–12. http://dx.doi.org/10.1177/01926233211056872.

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Aneurysms of the ascending aorta, unrelated to xenobiotic administration, are described in 5 rats and 2 mice in nonclinical safety studies conducted at Charles River Laboratories (CRL) sites over the past 10 years. The most prominent microscopic finding was focal dilation with disruption of the wall of the ascending aorta with chronic adventitial inflammation or fibroplasia. The pathogenesis of this finding is unknown. There were no associated macroscopic findings, clinical abnormalities, or vascular lesions elsewhere. The results of a search of historical control data from toxicology studies

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41

Derosa, Christopher T., Yee-Wan Stevens, Jewell D. Wilson, et al. "The Agency for Toxic Substances and Disease Registry's Role in Development and Application of Biomarkers in Public Health Practice." Toxicology and Industrial Health 9, no. 6 (1993): 979–94. http://dx.doi.org/10.1177/074823379300900601.

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717 An overview of the Agency for Toxic Substances and Disease Registry's (ATSDR) biomarker program is presented in the context of the paradigm for biomarkers developed by the National Research Council (NRC, 1987, 1991). The status and projected utility of four biomarker studies conducted by NRC and sponsored by ATSDR, the Environmental Protection Agency (EPA), and the National Institute of Environmental Health Sciences (NIEHS) are discussed. These studies include a review of relevant research on biomarkers for specific toxicologic end points, including reproductive toxicology, pulmonary toxic

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42

Robinson, J. Paul, and R. W. Pfeifer. "New Technologies for Use in Toxicology Studies: Monitoring the Effects of Xenobiotics on Immune Function." Journal of the American College of Toxicology 9, no. 3 (1990): 303–17. http://dx.doi.org/10.3109/10915819009078741.

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New developments in flow cytometry are now being applied in toxicology studies. There are several reasons for using this technology. First, techniques are well characterized to measure functional parameters of single cells. Such measurements can be directly related to perturbations by xenobiotics, cell-mediated immune responses, or trauma. Second, there is a clear indication for movement toward in vitro systems as highly objective assessments of toxicologic interactions. By measuring specific cell functions at the single cell level, it is possible to define a range of normal responses. More im

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43

Gussow, Leon. "Toxicology Rounds." Emergency Medicine News 42, no. 9 (2020): 22. http://dx.doi.org/10.1097/01.eem.0000697748.39768.b8.

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44

Flanagan, Robert J., Geraldine Connally, and Julie M. Evans. "Analytical Toxicology." Toxicological Reviews 24, no. 1 (2005): 63–71. http://dx.doi.org/10.2165/00139709-200524010-00005.

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45

Needleman, Herbert L. "Behavioral Toxicology." Environmental Health Perspectives 103 (September 1995): 77. http://dx.doi.org/10.2307/3432352.

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46

Davis, Gregory G. "Forensic Toxicology." American Society for Clinical Laboratory Science 25, no. 2 (2012): 120–24. http://dx.doi.org/10.29074/ascls.25.2.120.

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47

Charan Gowda, BK, BSivapatha Sundharam, Jyothi Mahadesh, and Mukund. "Oral-toxicology." Journal of Forensic Dental Sciences 6, no. 1 (2014): 3. http://dx.doi.org/10.4103/0975-1475.127763.

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48

Jelinek, George A. "Total toxicology." Medical Journal of Australia 192, no. 1 (2010): 43. http://dx.doi.org/10.5694/j.1326-5377.2010.tb03402.x.

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49

Karr, James R. "Beyond Toxicology." BioScience 40, no. 6 (1990): 420. http://dx.doi.org/10.2307/1311380.

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50

Mattu, Amal. "Toxicology Emergencies." Emergency Medicine Clinics of North America 40, no. 2 (2022): xiii—xiv. http://dx.doi.org/10.1016/j.emc.2022.03.001.

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