Relevant bibliographies by topics / Toxicometabolomics

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Toxicometabolomics'

Author: Grafiati
Published: 5 June 2025
Last updated: 16 July 2025

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Journal articles on the topic "Toxicometabolomics"

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Araújo, Ana Margarida, Félix Carvalho, Paula Guedes de Pinho, and Márcia Carvalho. "Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions." Metabolites 11, no. 10 (2021): 692. http://dx.doi.org/10.3390/metabo11100692.

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Given the high biological impact of classical and emerging toxicants, a sensitive and comprehensive assessment of the hazards and risks of these substances to organisms is urgently needed. In this sense, toxicometabolomics emerged as a new and growing field in life sciences, which use metabolomics to provide new sets of susceptibility, exposure, and/or effects biomarkers; and to characterize in detail the metabolic responses and altered biological pathways that various stressful stimuli cause in many organisms. The present review focuses on the analytical platforms and the typical workflow emp
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Bouhifd, Mounir, Thomas Hartung, Helena T. Hogberg, Andre Kleensang, and Liang Zhao. "Review: Toxicometabolomics." Journal of Applied Toxicology 33, no. 12 (2013): 1365–83. http://dx.doi.org/10.1002/jat.2874.

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García-Barrera, Tamara, Gema Rodríguez-Moro, Belén Callejón-Leblic, Borrego Ana Arias, and José Luis Gómez-Ariza. "Mass spectrometry based analytical approaches and pitfalls for toxicometabolomics of arsenic in mammals: A tutorial review." Analytica Chimica Acta 1000 (November 2, 2017): 41e66. https://doi.org/10.1016/j.aca.2017.10.019.

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The present review focus on the analytical platforms and the workflow for toxicometabolomics with a special emphasis on their strengths and pitfalls presenting as a case study the toxicometabolomics of arsenic in mammals. Although powerful analytical methods and techniques are currently available for metabolomics, the main “bottleneck” is still the absence of unified protocols for sample preparation (e.g. quenching, solvents used) as well as several important factors in toxicometabolomics, which drastically affect the metabolism (e.g. selection of mode
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da Silva, Katyeny Manuela, Elias Iturrospe, Chloe Bars, et al. "Mass Spectrometry-Based Zebrafish Toxicometabolomics: A Review of Analytical and Data Quality Challenges." Metabolites 11, no. 9 (2021): 635. http://dx.doi.org/10.3390/metabo11090635.

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Metabolomics has achieved great progress over the last 20 years, and it is currently considered a mature research field. As a result, the number of applications in toxicology, biomarker, and drug discovery has also increased. Toxicometabolomics has emerged as a powerful strategy to provide complementary information to study molecular-level toxic effects, which can be combined with a wide range of toxicological assessments and models. The zebrafish model has gained importance in recent decades as a bridging tool between in vitro assays and mammalian in vivo studies in the field of toxicology. F
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Ribbenstedt, Anton, Malte Posselt, Carl Brunius, and Jonathan P. Benskin. "In-plate toxicometabolomics of single zebrafish embryos." Molecular Omics 16, no. 3 (2020): 185–94. http://dx.doi.org/10.1039/d0mo00007h.

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Radilov, Andrey Stanislavovich, and Anton Igorevich Ukolov. "Toxicometabolomics — integration of preventive and analytical toxicology." Toxicological Review 30, no. 5 (2022): 286–96. http://dx.doi.org/10.47470/0869-7922-2022-30-5-286-296.

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Introduction. This paper considers aspects of the development of a toxicokinetically based model for scaling the limit concentrations of toxic compounds in the air, estimating the coefficients of their material cumulation, as well as estimating the concentrations of toxicants in biological media expected in the course of biological control. The results of testing the model on the example of organophosphorus pesticides (OP) and volatile industrial pollutants (VIP) are presented. Material and methods. For experimental modeling of intoxication, male chinchilla rabbits obtained from the Rappolovo
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Gebreab, Kiflom Y., Muhamed N. H. Eeza, Tianyu Bai, et al. "Comparative toxicometabolomics of perfluorooctanoic acid (PFOA) and next-generation perfluoroalkyl substances." Environmental Pollution 265 (October 2020): 114928. http://dx.doi.org/10.1016/j.envpol.2020.114928.

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Silva, T. D., C. Alves, G. M. Pereira, et al. "P10-23: Toxicometabolomics of atmospheric particulate matter (PM) in neuronal cells." Toxicology Letters 384 (September 2023): S154. http://dx.doi.org/10.1016/s0378-4274(23)00630-6.

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Kim, Kyu-Bong, Ji-Young Yang, Seung Jun Kwack, et al. "Toxicometabolomics of Urinary Biomarkers for Human Gastric Cancer in a Mouse Model." Journal of Toxicology and Environmental Health, Part A 73, no. 21-22 (2010): 1420–30. http://dx.doi.org/10.1080/15287394.2010.511545.

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Ryu, Sung Ha, Ji Won Kim, Dahye Yoon, Suhkmann Kim, and Kyu-Bong Kim. "Serum and urine toxicometabolomics following gentamicin-induced nephrotoxicity in male Sprague-Dawley rats." Journal of Toxicology and Environmental Health, Part A 81, no. 11 (2018): 408–20. http://dx.doi.org/10.1080/15287394.2018.1451180.

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Dissertations / Theses on the topic "Toxicometabolomics"

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Manier, Sascha Kevin [Verfasser]. "Toxicometabolomics of cathinone derivatives / Sascha Kevin Manier." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2020. http://d-nb.info/122297391X/34.

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Araújo, Ana Margarida Carvalho. "Toxicometabolomics of amphetaminic derivates in in vitro and in vivo experimental models." Doctoral thesis, 2021. https://hdl.handle.net/10216/133680.

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Araújo, Ana Margarida Carvalho. "Toxicometabolomics of amphetaminic derivates in in vitro and in vivo experimental models." Tese, 2021. https://hdl.handle.net/10216/133680.

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Book chapters on the topic "Toxicometabolomics"

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Gómez-Ariza, José Luis, Tamara García-Barrera, Belén Callejón-Leblic, and Gema Rodríguez Moro. "Environmental Metabolomics and Toxicometabolomics in Marine Pollution Assessment." In Environmental Problems in Marine Biology. CRC Press, 2017. http://dx.doi.org/10.1201/9781315119113-11.

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Milburn, Michael V., John A. Ryals, and Lining Guo. "Toxicometabolomics." In A Comprehensive Guide to Toxicology in Preclinical Drug Development. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-387815-1.00034-4.

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Milburn, M. V., J. A. Ryals, and L. Guo. "Toxicometabolomics." In A Comprehensive Guide to Toxicology in Nonclinical Drug Development. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-803620-4.00033-5.

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Nurain, Ismaila O. "Oxidative stress, Reactive species, Antibiotics, Antimicrobial therapy, Bacteria, Adaptations." In Therapeutic Use of Plant Secondary Metabolites. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815050622122010016.

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Medicinal plants are particularly important biobanks for chemical andstructural diversity and the identification and characterization of druggable agents inthe pharmaceutical developmental processes. Many researchers are now striving toupgrade traditional medicine to match modern medicine. One of the greatest means todo this is by omics sciences. This chapter focuses on the description of ‘omicstechnologies as a pivotal tool in the standardization and modernization of phytotherapy.Some of the ‘omics approaches discussed are genomics, proteomics, chemoproteomics,glycoproteomics, immunoproteomics, interactomics, transcriptomics, metabolomics,toxicogenomics, pharcogenomics, pharmacometabolomics, phytochemomics,toxicometabolomics, phenomics, cytomics, and metallomics. These fields of sciencesare very important for the understanding of components and mechanisms of actions ofcells, tissues, organs, and systems with disease mechanisms. Thus, ‘omics scienceshave been gaining ground and acceptance in the drug development processes ofmodern medicine and as a precision medicine for disease management. Overall,utilizing ‘omics technologies as tools for the standardization and modernization ofphytotherapy is a promising way to improve traditional medicine in tackling severallife-threatening and deadly diseases.
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Journal articles
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