Academic literature on the topic 'Tp-e interval'
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Journal articles on the topic "Tp-e interval"
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Afsin, Abdulmecit, Ramazan Asoğlu, Mehmet Hamdi Orum, and Elvan Cicekci. "Evaluation of TP-E Interval and TP-E/QT Ratio in Panic Disorder." Medicina 56, no. 5 (2020): 215. http://dx.doi.org/10.3390/medicina56050215.
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Background and Objectives: The autonomic nervous system (ANS) is involved in panic disorders. ANS dysfunction has been shown to be associated with ventricular arrhythmia and increased heterogeneity of ventricular repolarization. However, there remains limited evidence of the relationship between panic disorders and ventricular depolarization markers, including the Tp-e interval and Tp-e/QT ratio. This study aimed to evaluate ventricular repolarization parameters in patients with panic disorder. Materials and Methods: In total, 40 patients with panic disorder, diagnosed using the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria, were included in the study group. The control group comprised of 50 age- and sex-matched healthy individuals. A standard 12 lead electrocardiogram was recorded on all participants, and heart rate, QT interval, QRS duration, Tp-e interval, and Tp-e/QT ratio were measured. Results: QRS durations and QT intervals were similar in the study and control groups. Compared to the control group, QTd, Tp-e, and cTp-e intervals as well as Tp-e/QT and Tp-e/QTc ratios were significantly increased in patients with panic disorder (p < 0.05 for all). In the study group, the Severity Measure for Panic Disorder—Adult score had a significant positive correlation with the Tp-e interval (r = 0.369, p < 0001), cTp-e interval (r = 0.531, p < 0.001), Tp-e/QT ratio (r = 0.358, p = 0.001), and Tp-e/QTc ratio (r = 0.351, p = 0.001). Conclusion: These findings indicate that panic disorders are associated with increased ventricular repolarization heterogeneity, which may be attributed to ANS dysregulation.
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Tural Onur, Seda, Imran Onur, Sinem Sokucu, et al. "Tp-E Interval in Sarcoidosis." Chest 148, no. 4 (2015): 399A. http://dx.doi.org/10.1378/chest.2276210.
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Sahin, Kader Eliz, Mesut Karatas, Sezgin Barutcu, and Ibrahim Halil Inanc. "Evaluation of the Electrocardiographic Tp-e, Tp-e/QT, and Tp-e/QTc Parameters in Patients with Non-Alcoholic Liver Disease." Medicina 61, no. 4 (2025): 766. https://doi.org/10.3390/medicina61040766.
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Background and Objectives: Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease associated with significant morbidity, including cardiovascular complications. This study investigates the relationship between NAFLD and electrocardiographic parameters indicative of ventricular arrhythmia risk. Materials and Methods: We conducted a cross-sectional study enrolling 136 patients with NAFLD and 136 healthy controls. Electrocardiographic parameters—Tp-e interval, QT and corrected QT (QTc) intervals, and Tp-e/QTc ratio—were measured and compared between groups. Results: Patients with NAFLD exhibited significantly higher Tp-e, QTc, Tp-e/QT ratio, and Tp-e/QTc ratio (p < 0.001, for all) than controls. Subgroup analysis showed progressive increases in Tp-e and Tp-e/QT ratio correlating with NAFLD severity (p < 0.001 and p = 0.001, respectively, for grade 1 vs. grade 2; p < 0.001 and p = 0.001, respectively, for grade 1 vs. grade 3). ROC analysis indicated that the Tp-e interval was a strong predictor for identifying grade 2 or more NAFLD (AUC 0.887, p < 0.001). Conclusions: Our findings highlight the association of NAFLD with prolonged electrocardiographic intervals that may predispose patients to ventricular arrhythmias. These parameters can serve as valuable markers for cardiac risk stratification in patients with NAFLD, suggesting the need for vigilant cardiac follow-up in this population.
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ÇETİNKAYA, Zeki, Şaban KELEŞOĞLU, Ferhat GÖKAY, and Yücel YILMAZ. "Evaluation of Tp-e interval, Tp-e/QT, and Tp-e/QTc ratio in primary hyperparathyroidism before and after parathyroidectomy." Anatolian Current Medical Journal 6, no. 1 (2024): 73–79. http://dx.doi.org/10.38053/acmj.1382439.
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Aims: This study aimed to evaluate Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratios, which are new ventricular repolarization (VR) parameters in primary hyperparathyroidism (PHPT) patients, and also investigate the potential effect of parathyroidectomy (PTx) on these parameters. Methods: In total, 27 patients with PHPT who underwent PTx and 25 control subjects were selected for our study. Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratios of patients planned for PTx were compared to healthy matched controls. Electrocardiographic parameters measured 6 months after the surgery were also compared with preoperative values for each patient. Results: Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio were significantly higher in PHPT patients compared to the control group (p&lt;0.001, for all).It was observed that the parameters mentioned after surgery decreased significantly, and there was no statistical difference when compared to the control group.The correlation analysis revealed a significant and positive correlation between corrected calcium (CCa) and PTH levels with Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio (for Ca; r=0.515, p=0.006; r=0.398, p=0.040; r=0.797, p&lt;0.001 respectively vs. for PTH; r=538, p=0.04; r=0.422, p=0.028; r=0.812, p&lt;0.001 respectively). Conclusions: This study showed that Tp-e interval, Tp-e/QT, and Tp-e/QTc ratios were prolonged in PHPT.These values, which are accepted as an indicator of sudden cardiac death after PTx, decreased significantly. In addition, both high PTH and high calcium(Ca) levels appear to have the potential to cause arrhythmogenic effects separately.
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Dişyapar, Mustafa Kaan, Şaban Keleşoğlu, Nur Aleyna Yetkin, Fatma Özdemir, and Yücel Yılmaz. "Evaluation of the risk of sudden cardiac death in obstructive sleep apnea syndrome patients with Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio." Journal of Cardiology & Cardiovascular Surgery 1, no. 4 (2023): 82–85. http://dx.doi.org/10.51271/jccvs-0021.
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Aims: Obstructive sleep apnea syndrome (OSAS) is a disorder characterized by recurrent collapse of the upper airway during sleep. OSAS is associated with an increased risk of cardiovascular morbidity and mortality. Tpeak to Trend (Tp-e) interval, the Tp-e interval/QT interval (Tp-e/QT) ratio, and the Tp-e interval/corrected QT interval (Tp-e/QTc) ratio, are associated with ventricular arrhythmias and sudden cardiac death in various disease groups. we aimed to investigate the relationship between changes in the new arrhythmia markers Tp-e interval, Tp-e/QT and Tp-e/QTc ratios in OSAS patients. Methods: The study looked at 45 people with OSAS (32 men) over the age of 18 and 43 healthy people (27 men) who were diagnosed with OSAS through polysomnography in a sleep lab. Tp-e interval, Tp-e/QT and Tp-e/QTc ratios were calculated on the ECG. Results: The QT interval was shorter in the patient group than in the control group, in contrast to the QTc interval, which was comparable between groups (p = 0.006 and 0.810 in the patient and control groups, respectively). The Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio were significantly higher in PHPT patients included in the patient group compared to those included in the control group (p<0.01 in total). Conclusion: The Tp-e interval, Tp-e/QT, and Tp-e/QTc ratios were prolonged in OSAS patients. These findings suggest that OSAS patients may be predisposed to severe ventricular arrhythmias.
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ÇELİK, İBRAHİM ETEM, SEVDE NUR FIRAT, UĞUR BOZKURT, MİKAİL YARLOĞLUEŞ, MUSTAFA DURAN, and SANİ NAMIK MURAT. "Assessment of Tp-e interval, Tp-e/QT and Tp-e/QTc ratios in patients with acromegaly." Turkish Journal of Medical Sciences 52, no. 3 (2022): 809–15. http://dx.doi.org/10.55730/1300-0144.5377.
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Demirtas, Derya, Hilmi Erdem Sumbul, Atilla Bulut, et al. "Tp-e interval, Tp-e/QT and Tp-e/QTc ratio in hypertensive patients with primary aldosteronism." Clinical and Experimental Hypertension 42, no. 1 (2019): 93–98. http://dx.doi.org/10.1080/10641963.2019.1632341.
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Tokatlı, Alptuğ, Tevfik Fikret İlgenli, Onur Akpınar, Fethi Kılıçaslan, Mehmet Uzun, and Bekir Sıtkı Cebeci. "Effect of Cigarette Smoking on Tp-e interval, Tp-e/QT Ratio and Tp-e/QTc Ratio." Journal of the American College of Cardiology 62, no. 18 (2013): C144. http://dx.doi.org/10.1016/j.jacc.2013.08.429.
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Demir, C., and Mehmet Demir. "Evaluation of Tp-e Interval and Tp-e/QT Ratio in Patients with Chronic Hepatitis B." Prague Medical Report 114, no. 4 (2013): 239–45. http://dx.doi.org/10.14712/23362936.2014.13.
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Chronic hepatitis B (CHB) is a chronic inflammatory viral disorder. Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarisation and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. Impaired autonomic function has been described in patients with CHB. The aim of this study was to evaluate ventricular repolarisation by using Tp-e interval and Tp-e/QT ratio in patients with CHB, and to assess the relation with inflammation. Fifty-five patients with CHB and 50 controls were included. Tp-e interval and Tp-e/QT ratio were measured from the 12-lead electrocardiogram, and Tp-e interval corrected for heart rate. These parameters were compared between groups. In electrocardiographic parameters analysis, QT dispersion (QTd) and corrected QTd were significantly increased in CHB patients compared to the controls (38.3 ± 10.9 vs. 28.5 ± 7.3 mi- lliseconds and 39.5 ± 11.2 vs. 29.6 ± 7.6 milliseconds, P=0.01 and P<0.001, respectively). cTp-e interval and Tp-e/QT ratio were also significantly higher in CHB patients (85.3 ± 8.2 vs. 74.5 ± 7.4 milliseconds and 0.24 ± 0.02 vs. 0.18 ± 0.02, all P-value < 0.001). Our study revealed that Tp-e interval and Tp-e/QT ratio were increased in CHB patients.
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Yahia, Mohamed, Amgad Elshazly, and Maha Yousif. "Study of electrocardiographic indices of myocardial repolarization in patients with obstructive sleep apnea." Egyptian Journal of Chest Diseases and Tuberculosis 73, no. 2 (2024): 175–80. http://dx.doi.org/10.4103/ecdt.ecdt_31_23.
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Abstract Background Obstructive sleep apnea (OSA) is a sleep disorder manifested by airflow severe reduction or stoppage during breathing exertion. OSA cases had a higher incidence of ventricular arrhythmias, according to reports. Aim This research aimed to determine ventricular repolarization in OSA cases using the electrocardiographic indices of ventricular repolarization. Patients and methods This observational research involved 60 patients who underwent overnight polysomnography (PSG). 20 cases with normal PSG were employed as controls. Moderate or severe OSA cases were employed as study group. Tp-e, QTc intervals & Tp-e/QTc ratios measurement was performed in all patients. Results Patients had significantly prolonged QTc intervals, Tp-e intervals & Tp-e/QTc ratio compared to controls (446.4 ± 36.99 ms vs. 408.6 ± 25.23 ms, 86.12 ± 17.63 ms vs. 66.65 ± 15.49 ms & 0.19 ± 0.04 vs. 0.16 ± 0.04 respectively, P<0.001). There was a significant positive correlation between OSA degree and Tp-e/QTc ratio (r=0.374, P=0.017), Tp-e/QT ratio (r=0.448, P=0.004) & Tp-e interval (r=0.377, P=0.016). There is also significant correlation between such repolarization indices and both lowest SpO2 and arousal index (P<0.05). Conclusions We concluded a significant positive correlation between OSA degree and Tp-e/QTc, Tp-e/QT ratios & Tp-e interval. OSA is associated with prolonged Tp-e/QTc & Tp-e/QT ratios and a prolonged Tp-e interval.
Dissertations / Theses on the topic "Tp-e interval"
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Chen, Yu-Pin, and 陳宇斌. "Research on Prolonged QT or Tp-e Intervals in Male Workers Affected by Sleep Apnea or Hyperarousal across Pre-sleep and Sleep-Stages." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/00972367126155518726.
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碩士<br>中山醫學大學<br>生物醫學科學學系碩士班<br>103<br>Objective: Obstructive sleep apnea and repetitive arousals enhance sympathetic activities, and potentially cause electrical disturbances during ventricular repolarization. Spectral parameters of heart rate variability (HRV) and heart rate corrected QT interval (QTc), the interval between peak and the end of T wave (Tp-e), Tp-e/QT ratio, and Tp-e/QTc ratio are promising surrogates for autonomic nervous activity and electrocardiographic indices of ventricular arrhythmogenesis, respectively. We aim to investigate that QTc, Tp-e, Tp-e/QT, and Tp-e/QTc are greater in male subjects with sleep apnea or hyperaousal over various night-sleep-stages and fluctuate with corresponding HRV parameters.
Material and method: Natural-logarithm-transformed power values of HRV, QTc, Tp-e, Tp-e/QT, and Tp-e/QTc from one 5-min arousal-free electrocardiography segment in each of pre-sleep-wakefulness (AWK), non-rapid-eye-movement stage 2 (N2), slow-wave (N3), and the latest rapid-eye-movement sleep (REM) were computed in 101 healthy males (43.5±7.9 yrs., 26.7±3.3 kg/m2) with wide-ranged apnea-hypopnea and arousal indices (17.7±18.3 and 33.0±17.6/hr., respectively).
Results: All participants were sub-grouped into normal, mild-moderate and severe OSA or low, moderate and high arousal in frequency by apnea-hypopnea index (AHI) or arousal index, which significantly correlated by QTc or Tp-e by linear regression analyses. No differences were found in fluctuation of each HRV parameter across various stages among three subgroups categorized by AHI values. QTc values at stages AWK, N2 and N3 are greater in severe OSA patient than normal control (468±40 vs 431±39; 469±46 vs 430±40; and 472±50 vs 434±41 ms; each p value is 0.01, 0.01 and 0.02 respectively), whereas Tp-e values sequentially decreased from high, middle and low arousal subjects at stages AWK, N2 and N3 (each p value is 0.00, 0.01 and 0.02) but with constant Tp-e/QT and Tp-e/QTc ratios. Though HRV spectral parameters fluctuating over various presleep wakefulness and three sleep stages as previous reports, QTc, Tp-e, Tp-e/QT ratio, and Tp-e/QTc ratio are not found oscillate with these corresponding automatic nervous indices.
Conclusions: It might suggest that severe OSA or repetitive arousals likely have a higher risk for nocturnal arrhythmia accounted for by prolonged repolarization and/or depolarization periods of ventricles and long-term accumulating adverse effect of OSA or arousals, rather than real-timed autonomic activities, play a major role in the dysfunction of ventricular repolarization.
Book chapters on the topic "Tp-e interval"
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Bacskai-Atkari, Julia. "Information structure, functional left peripheries, and the history of a Hungarian interrogative marker." In Functional Heads Across Time. Oxford University PressOxford, 2022. http://dx.doi.org/10.1093/oso/9780198871538.003.0006.
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Abstract This article examines diachronic changes affecting functional left peripheries in Hungarian embedded polar interrogatives. While Old Hungarian embedded polar questions were introduced by an interrogative complementiser (ha ‘if’), similarly to Germanic languages, Modern Hungarian polar questions are marked by the clause-internal element -e. Middle Hungarian represents an intermediate stage in which both elements were present. There are two factors responsible for this change. First, Proto-Hungarian saw a major word order change from strict SOV to a much freer word order in which various left-peripheral positions were established, including that of the FP on top of the TP: this came to host wh-constituents and focussed elements. As a consequence, the overt marking of [Q] in constituent questions grammaticalized in the FP. Second, this had an analogical effect on polar questions, ultimately resulting in the grammaticalization of -e as an F head specified for overtly marking [Q].
Conference papers on the topic "Tp-e interval"
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Muller, KG, PHC França, MF Mastroeni, and MAA Prado. "INTERVALOS DE REFERÊNCIA POR MÉTODO INDIRETO PARA MARCADORES SÉRICOS HEPÁTICOS EM CRIANÇAS BRASILEIRAS." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.6785.
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Objetivo: Determinar intervalos de referência, em crianças brasileiras, para os marcadores séricos hepáticos alanina aminotransferase (ALT), aspartato aminotransferase (AST), fosfatase alcalina (FAL) e gama glutamiltransferase (GGT) por meio de método indireto. Método: Recuperaram-se os dados, de janeiro de 2017 a dezembro de 2018, do sistema de informação laboratorial de uma empresa de medicina diagnóstica com várias marcas distribuídas no Brasil. O grupo amostral inicial englobou 26.718 crianças das cinco regiões do Brasil, de 0 a 12 anos incompletos, que realizaram pelo menos a dosagem de ALT e AST na plataforma Roche Cobas. Aplicaram-se os critérios de exclusão de indivíduos com base na realização de mais de uma dosagem do mesmo marcador sérico hepático durante o período do estudo e a ausência de qualquer anormalidade nos exames laboratoriais correlatos. Os dados do grupo amostral final foram utilizados para a determinação dos intervalos de referência, utilizando-se os percentis de 2,5 a 97,5. Conclusão: O comportamento das atividades séricas das enzimas pesquisadas foi semelhante ao de outros estudos internacionais por abordagem direta ou indireta com população infantil e adulta, mas os valores encontrados nesta pesquisa se diferem dessas populações, o que reforça a importância de se estabelecer intervalos de referência específicos para a população infantil brasileira. Os resultados deste estudo são clinicamente úteis e podem permitir aos profissionais de saúde requisitantes desses exames laboratoriais interpretarem de forma mais adequada os resultados emitidos e decidir por condutas clínicas mais eficazes. Além disso, eles poderão ser utilizados para o planejamento de pesquisas similares para outros analitos importantes na pediatria. Referências: 1. Jones GRD, Haeckel R, Loh TP et al. Indirect methods for reference interval determination review and recommendations. Clin Chem Lab Med 2018; 57: 20-9.
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Meruva, Prathik, Alexander Michlberger, Pruthvi Bachu, and Daniel Christopher Bitsis. "Optimizing Hybrid Powertrains for Light Duty Commercial Vehicles." In WCX SAE World Congress Experience. SAE International, 2025. https://doi.org/10.4271/2025-01-8544.
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<div class="section abstract"><div class="htmlview paragraph">Battery electric vehicles (BEVs) are well-suited for many passenger vehicle applications, but high cost, short range, and long recharging times have limited their growth in commercial vehicle markets. These constraints can be eliminated with plug-in hybrid electric vehicles (PHEVs) which combine many benefits of BEVs with those of conventional vehicles. In this study, research was conducted to determine the optimal hybrid electric powertrain system for a Class 3, light duty commercial vehicle. The key technologies used in this hybrid powertrain include engine downsizing, P3 architecture hybridization, and active thermal management of aftertreatment. A vehicle cost of ownership analysis was conducted to determine the economic viability, a very important consideration for commercial vehicles. Several combinations of E-motor and battery pack sizes were evaluated during the cost analysis and the best possible configuration was determined. The resulting vehicle powertrain demonstrated ~60% reduction in CO<sub>2</sub> over the World Harmonized Light Duty Transient Cycle (WLTC) and Federal Transient Procedure (FTP75) test cycles compared to the baseline internal combustion engine (ICE) vehicle. The NO<sub>X</sub> emissions were also evaluated during those test cycles, and the test results indicated that intermittent engine operation associated with Plug-in Hybrid Electric Vehicle (PHEV) operation, can result in higher NO<sub>X</sub> emissions. Advanced aftertreatment thermal management strategies are required to reduce NO<sub>X</sub> emissions in PHEVs. Finally, an exhaust heater was used to reduce tailpipe (TP) NO<sub>X</sub> emissions, and a pathway for even lower NO<sub>X</sub> emissions is identified.</div></div>