Academic literature on the topic 'Traditional medicine – Cambodia'

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Journal articles on the topic "Traditional medicine – Cambodia"

1

Ros, Bandeth, Gillian Lê, Barbara McPake, and Suzanne Fustukian. "The commercialization of traditional medicine in modern Cambodia." Health Policy and Planning 33, no. 1 (2017): 9–16. http://dx.doi.org/10.1093/heapol/czx144.

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2

CLEMENTS, TOM, MARTIN GILBERT, HUGO J. RAINEY, et al. "Vultures in Cambodia: population, threats and conservation." Bird Conservation International 23, no. 1 (2012): 7–24. http://dx.doi.org/10.1017/s0959270912000093.

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SummaryAsian vultures have undergone dramatic declines of 90–99% in the Indian Subcontinent, as a consequence of poisoning by veterinary use of the drug diclofenac, and are at a high risk of extinction. Cambodia supports one of the only populations of three species (White-rumped Vulture Gyps bengalensis, Slender-billed Vulture G. tenuirostris and Red-headed Vulture Sarcogyps calvus) outside of South Asia where diclofenac use is not widespread. Conservation of the Cambodian sub-populations is therefore a global priority. This study analyses the results of a long-term research programme into Cambodian vultures that was initiated in 2004. Population sizes of each species are estimated at 50–200+ individuals, ranging across an area of approximately 300 km by 250 km, including adjacent areas in Laos and Vietnam. The principal causes of vulture mortality were poisoning (73%), probably as an accidental consequence of local hunting and fishing practices, and hunting or capture for traditional medicine (15%). This represents a significant loss from such a small population of long-lived, slow breeding, species such as vultures. Cambodian vultures are severely food limited and are primarily dependent on domestic ungulate carcasses, as wild ungulate populations have been severely depleted over the past 20 years. Local people across the vulture range still follow traditional animal husbandry practices, including releasing livestock into the open deciduous dipterocarp forest areas when they are not needed for work, providing the food source. Reducing threats through limiting the use of poisons (which are also harmful for human health) and supplementary food provisioning in the short to medium-term through ‘vulture restaurants’ is critical if Cambodian vultures are to be conserved.
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3

Chea, Aun, Marie-Caroline Jonville, Sok-Siya Bun, et al. "In vitro Antimicrobial Activity of Plants used in Cambodian Traditional Medicine." American Journal of Chinese Medicine 35, no. 05 (2007): 867–73. http://dx.doi.org/10.1142/s0192415x07005338.

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The purpose of the present study was to screen 27 plant species used in the traditional medicine of Cambodia for in vitro antibacterial and antifungal activities. Thirty-three methanolic extracts were tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Mycobacterium smegmatis and Candida albicans. Screened by disk diffusion assay, the extracts showed antimicrobial activity especially on Gram-positive bacteria. None of the crude methanolic extracts showed activity against P. aeruginosa. Twenty-five selected extracts were evaluated using a micro-dilution test. Harrisonia perforata (roots) and Hymenodictyon excelsum (bark) exhibited a bactericidal effect against S. aureus at a concentration of 500 μg/ml. Azadirachta indica (bark), Harrisonia perforata (roots and stem) and Shorea obtusa (roots) exhibited a bactericidal effect against M. smegmatis at 250 μg/ml.
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Cheung, Peter, and George Spears. "Illness Aetiology Constructs, Health Status and Use of Health Services among Cambodians in New Zealand." Australian & New Zealand Journal of Psychiatry 29, no. 2 (1995): 257–65. http://dx.doi.org/10.1080/00048679509075918.

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Objective: The objectives of this study were to determine, among all adult Cambodians living in Dunedin: prevalence of illness aetiology beliefs; psychiatric and physical health status; pattern of use of health services; relationships between use of health services and demographic factors, illness aetiology constructs and health status; and problems encountered and improvements desired in the local health services. Method: 223 (i.e. 93.3% of all) adult Cambodians living in Dunedin were assessed, using a structured interview, in relation to their sociodemographic status, illness aetiology beliefs, physical health status and use of health services. The 28-item version of the General Health Questionnaire was used to assess psychiatric status. Results: Subjects held multiple indigenous and Western illness aetiology constructs. Psychiatric morbidity using the 28item of the General Health Questionnaire (GHQ28) cutoff of 3/4 was 15.7% despite this only six subjects had ever used specialist psychiatric services. Malaria, intestinal parasitic infestations and heart conditions were the three most frequently reported physical problems. Most subjects had used traditional services in Cambodia but very few had used them in New Zealand. Health service was related to duration of stay in New Zealand. Socio-economic status, both physical and psychiatric health status and some illness aetiology constructs. One hundred and forty-two (63.7%) subjects reported problems with use of health services in Dunedin. Conclusion: Despite methodological limitations, some useful preliminary data on factors pertaining to use of and satisfaction with health services among Cambodians were collected. Future research should examine family characteristics and the decision-making processes that determine service use.
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Ay, N. V., Altantsetseg Kh, Enkhchimeg V, and Baatartsogt O. "ANTI-INFLAMMATORY EFFECT OF PLANTAGO SP ETHANOLIC EXTRACT IN MURINE RAW264.7 MACROPHAGE CELLS." Mongolian Journal of Agricultural Sciences 21, no. 02 (2018): 35–42. http://dx.doi.org/10.5564/mjas.v21i02.903.

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Besides being recorded as a traditional medicine, nowadays, plantain plants (Plantago sp.) are appreciated in many more aspects. Plantain is a name applied both to a drug and to a vegetable in a number of countries as Vietnam, China, Cambodia, Laos and North American Indians [9, 13]. Plantago sp. traditionally used for treating wound, fever and inflammation in Asia. This study aimed to investigate the anti-inflammatory activity of ethanolic extracts of Plantago sp. including P. major L. and P. depressa Willd. on RAW 264.7 murine macrophage cells. Cells were treated with different concentration of the PAE extract (50, 100, 200, 400 μg/mL) with or without lipopolysaccharide (LPS) stimulation to evaluate its effect on cell viability, using CCK-8 assay. Nitric oxide (NO) production was assessed by Griess reagent on LPS-stimulated cells using preceding PEE treatment. Furthermore, mRNA expression of inflammmatory-related genes were evaluated by RT-PCR analysis. The results revealed that PEE treatment increased cell viability in naive cells whereas inhibited cell profileration in LPS-stimulated cell dose-dependently. In addition, NO emission and mRNA level of IL-1β, IL-6, iNOS, COX-2 and NF-κB decreased by dose dependant manner. As summary, PEE exhibits anti-inflammatory activity through inhibition of pro-inflammatory mediators mRNA expression in macrophages.
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6

Houy, Chandy, Sam Ol Ha, Margit Steinholt, Eystein Skjerve, and Hans Husum. "Delivery as Trauma: A Prospective Time-Cohort Study of Maternal and Perinatal Mortality in Rural Cambodia." Prehospital and Disaster Medicine 32, no. 2 (2017): 180–86. http://dx.doi.org/10.1017/s1049023x1600145x.

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AbstractObjectiveThe majority of maternal and perinatal deaths are preventable, but still women and newborns die due to insufficient Basic Life Support in low-resource communities. Drawing on experiences from successful wartime trauma systems, a three-tier chain-of-survival model was introduced as a means to reduce rural maternal and perinatal mortality.MethodsA study area of 266 villages in landmine-infested Northwestern Cambodia were selected based on remoteness and poverty. The five-year intervention from 2005 through 2009 was carried out as a prospective study. The years of formation in 2005 and 2006 were used as a baseline cohort for comparisons with later annual cohorts. Non-professional and professional birth attendants at village level, rural health centers (HCs), and three hospitals were merged with an operational prehospital trauma system. Staff at all levels were trained in life support and emergency obstetrics.FindingsThe maternal mortality rate was reduced from a baseline level of 0.73% to 0.12% in the year 2009 (95% CI Diff, 0.27-0.98; P<.01). The main reduction was observed in deliveries at village level assisted by traditional birth attendants (TBAs). There was a significant reduction in perinatal mortality rate by year from a baseline level at 3.5% to 1.0% in the year 2009 (95% CI Diff, 0.02-0.03; P<.01). Adjusting maternal and perinatal mortality rates for risk factors, the changes by time cohort remained a significant explanatory variable in the regression model.ConclusionThe results correspond to experiences from modern prehospital trauma systems: Basic Life Support reduces maternal and perinatal death if provided early. Trained TBAs are effective if well-integrated in maternal health programs.HouyC,HaSO,SteinholtM,SkjerveE,HusumH.Delivery as trauma: a prospective time-cohort study of maternal and perinatal mortality in rural Cambodia.Prehosp Disaster Med.2017;32(2):180–186.
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7

Bazzano, Alessandra N., Jeni A. Stolow, Ryan Duggal, Richard A. Oberhelman, and Chivorn Var. "Warming the postpartum body as a form of postnatal care: An ethnographic study of medical injections and traditional health practices in Cambodia." PLOS ONE 15, no. 2 (2020): e0228529. http://dx.doi.org/10.1371/journal.pone.0228529.

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8

Thay, Sovannara, Andrew Goldstein, Lena Sophia Goldstein, Vaishnavi Govind, Kruy Lim, and Chanthou Seang. "Prospective cohort study examining cervical cancer screening methods in HIV-positive and HIV-negative Cambodian Women: a comparison of human papilloma virus testing, visualization with acetic acid and digital colposcopy." BMJ Open 9, no. 2 (2019): e026887. http://dx.doi.org/10.1136/bmjopen-2018-026887.

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ObjectivesLogistical and economic issues make traditional cytology-based cervical cancer screening challenging in developing countries. Alternative, cost-effective, screening strategies must be developed to screen millions of women in resource-poor countries such as Cambodia.DesignA prospective cohort study during which all women underwent four cervical cancer screening methods: (1) self-sampled human papilloma virus (HPV) testing (careHPV system), (2) clinician-collected HPV testing, (3) visualization with acetic acid (VIA) and (4) digital colposcopy (DC) with the Enhanced Visual Assessment System (EVA).SettingA referral hospital in Phnom Penh, Cambodia.ParticipantsTwo hundred and fifty Cambodian women (129 HIV+, 121 HIV-). Subjects were recruited from the National Center for HIV/AIDS Dermatology and sexually transmitted disease (STD) cohort, the Sihanouk Hospital Center of Hope’s Rural Outreach Teams and the Pochentong Medical Center.ResultsFifty six of the 250 (22.4%) patients tested positive for high-risk HPV (hrHPV+). Thirty seven of the 129 HIV+ women were hrHPV+ (28.6%) whereas 19/121 HIV- women were hrHPV+ (15.7%) p=0.0154. Self-sampling HPV specimens identified 50/56 (89%) whereas physician-collected specimens identified 45/56 (80%) p=0.174. 95.2% of the patients felt comfortable obtaining HPV self-samples. Thirty seven of 250 women were VIA+. Thirty of 37 VIA+ women underwent confirmatory biopsies for cervical intraepithelial neoplasia (CIN) (26 CIN1, 4 CIN2+). The rate of confirmed dysplasia in the HIV+ group was 20/129 (15.5%) compared with 10/121 (8.26%) in HIV- women p=0.0291. The contemporaneous physician impressions of the DC images accurately differentiated between CIN1 and CIN2+ lesions in all 30 women having confirmatory biopsies.ConclusionsThe results of this study suggest potential modifications of the current cervical screening strategy that is currently being employed in Cambodia. The first step in this new strategy would be self-swabbing for hrHPV. Subsequently, hrHPV+ patients would have DC and immediate treatment based on colposcopic findings: cryotherapy for suspected CIN1 and loop electrosurgical excision procedure (LEEP) for suspected CIN2+.
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9

Katz, James, Kenneth Prescott, and Alan D. Woolf. "Strychnine poisoning from a cambodian traditional remedy." American Journal of Emergency Medicine 14, no. 5 (1996): 475–77. http://dx.doi.org/10.1016/s0735-6757(96)90157-6.

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10

Napagoda, Mayuri, Jana Gerstmeier, Hannah Butschek, et al. "The Anti-Inflammatory and Antimicrobial Potential of Selected Ethnomedicinal Plants from Sri Lanka." Molecules 25, no. 8 (2020): 1894. http://dx.doi.org/10.3390/molecules25081894.

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Traditional folk medicine in Sri Lanka is mostly based on plants and plant-derived products, however, many of these medicinal plant species are scientifically unexplored. Here, we evaluated the anti-inflammatory and antimicrobial potency of 28 different extracts prepared from seven popular medicinal plant species employed in Sri Lanka. The extracts were subjected to cell-based and cell-free assays of 5-lipoxygenase (5-LO), microsomal prostaglandin E2 synthase (mPGES)-1, and nitric oxide (NO) scavenging activity. Moreover, antibacterial and disinfectant activities were assessed. Characterization of secondary metabolites was achieved by gas chromatography coupled to mass spectrometric (GC-MS) analysis. n-Hexane- and dichloromethane-based extracts of Garcinia cambogia efficiently suppressed 5-LO activity in human neutrophils (IC50 = 0.92 and 1.39 µg/mL), and potently inhibited isolated human 5-LO (IC50 = 0.15 and 0.16 µg/mL) and mPGES-1 (IC50 = 0.29 and 0.49 µg/mL). Lipophilic extracts of Pothos scandens displayed potent inhibition of mPGES-1 only. A methanolic extract of Ophiorrhiza mungos caused significant NO scavenging activity. The lipophilic extracts of G. cambogia exhibited prominent antibacterial and disinfectant activities, and GC-MS analysis revealed the presence of fatty acids, sesquiterpenes and other types of secondary metabolites. Together, our results suggest the prospective utilization of G. cambogia as disinfective agent with potent anti-inflammatory properties.
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