Academic literature on the topic 'Trail Making Test A e B'

Introdução: Prejuízos na atenção, concentração e execução de tarefas, entre outras funções cognitivas, parecem ser frequentes em doentes com câncer e em cuidados paliativos e podem comprometer o cotidiano desses pacientes. No entanto, há poucos estudos sobre o tema e desconhecem-se testes validados para essa população no Brasil. Objetivo: Validar o Teste de Trilhas B (TT-B) para uso em pacientes com câncer em cuidados paliativos. Método: Trata-se de estudo metodológico, de validação de instrumento, que envolveu pacientes (n=94) em tratamento paliativo no Ambulatório de Quimioterapia do Instituto do Câncer do Estado de São Paulo e seus acompanhantes (n=39). Os avaliados realizaram o TT-B e responderam dados sócio-demográficos, sobre a presença e intensidade de dor, de fadiga, sobre a qualidade do sono, ansiedade e depressão, em dois momentos, com intervalo máximo de sete dias. Os doentes também foram caracterizados quanto à doença e tratamento. As validades convergente e divergente foram testadas pela correlação entre o desempenho no TT-B, mensurado pelo tempo para a realização do teste e o número de erros cometidos, com a intensidade da dor, da fadiga, da ansiedade, da depressão e do repouso atribuído ao sono da noite anterior às avaliações. A validade discriminante foi testada pela comparação do TT-B entre doentes e sadios. A estabilidade do TT-B, em doentes e sadios, foi avaliada por meio de teste e reteste. Resultados: Os doentes tinham câncer colo-retal (47,8%), câncer de mama (15,9%), a totalidade apresentava metástase, foram homens (52,1%), com idade média de 53 anos. Para os doentes, o tempo médio de realização do TT-B foi de 147,5 segundos na primeira e 132 segundos na segunda avaliação e o número de erros médio foi de 1 na primeira e 0,8 na segunda avaliação. Para os acompanhantes o tempo de realização do TT-B foi de 127,3 e 110,7 segundos na primeira e segunda avaliação respectivamente e o número de erros foi 0,9 na primeira e 0,6 na segunda avaliação. O instrumento discriminou doentes de sadios em relação ao tempo utilizado para a realização do teste na primeira (p=0,014) e na segunda (p=0,035) avaliação, indicando melhor desempenho para os sadios, mas não em relação ao número de erros. O teste foi estável entre os sadios nas duas avaliações, tanto em relação ao tempo (p=0,071) quanto em relação ao número de erros (p=0,352) e entre os doentes o instrumento foi estável apenas em relação ao número de erros (p=0,913). O TT-B não demonstrou correlações significativas com dor, fadiga, depressão, ansiedade e descanso, o que causou estranheza. Conclusão: O TT-B está em processo de validação. Mostrou-se capaz de discriminar doentes de sadios e foi estável entre os saudáveis. Recomenda-se a continuidade de estudos com amostras maiores e a utilização do TT-B em paralelo a outro instrumento que avalie a função executiva.<br>Introduction: Impairments in attention, concentration and execution of tasks, among other cognitive functions, seem to be frequent in patients with cancer in palliative care and they can affect patients daily life. However, there are few studies about the theme and to our knowledge there are no validated tests for this population in Brazil. Objective: To validate Trial Making TestB (TMT-B) for assessment of patients with cancer in palliative care. Methods: Methodological study to validate an instrument that involved patients (n=94) in palliative treatment at the Clinic of Chemotherapy of the Instituto do Câncer do Estado de São Paulo and their healthy accompanying person (n=39). Patients were tested on TMT-B and answered demographic data, questions about the presence of pain and intensity, fatigue, quality of sleep, anxiety and depression, in two moments, with maximum interval of seven days. The patients were also characterized according to disease and treatment. The convergent and divergent validities were tested by the correlation between the performance on TMT-B, measured by the amount of time required to complete the task and the number of mistakes, and pain intensity, fatigue, anxiety, depression and the rest attributed to sleep in the previous night before assessments. The discriminate validity was tested by the comparison of TMT-B between patients and healthy accompany persons. The stability of TMT-B, in patients and healthy companions was evaluated through test and re-test. Results: The patients had colorectal cancer (47.8%), followed by breast cancer (15.9%), the totality presented metastasis, most patients were men (52.1%), mean age was 53 years. For patients, mean time required to complete TMT-B was 147.5 seconds in the first and 132 seconds in the second assessments and the mean number of mistakes was 1 in the first and 0.8 in the second assessments. For the healthy accompany person, the time required to complete TMT-B was respectively 127.3 and 110.7 seconds in the first and second assessments and the number of mistakes was 0.9 in the first and 0.6 in the second assessments. The instrument discriminated patients from healthy accompany persons regarding time required to complete the test in the first (p=0.014) and second (p=0.035) assessments, indicating better performance for the healthy ones, but not in relation to the number of mistakes. The test was stable among healthy people in the two assessments regarding time (p=0.071) and number of mistakes (p=0.352); for patients, the instrument was stable only in relation to the number of mistakes (p=0.913). TMT-B did not demonstrate significant correlations with pain, fatigue, depression, anxiety and rest. Conclusion: TMT-B is in validation process. It was able to discriminate between patients and healthy accompany persons and was stable for the healthy ones. Further studies are recommended with larger samples as well as the use of TMT-B in parallel to other instrument that evaluates the executive function.

Mild Cognitive Impairment is a condition that affects an individual's thinking and decision making capabilities. Specifically, it is one where an individual's capabilities of memorizing, thinking and decision making are less efficient when compared to others. In order to diagnose this condition, a conventional method is to provide the subject with a small challenge they should be completed using pen and paper. This thesis focuses on how this method can be converted to a computer based test. A data visualization tool named Processing has been used to develop a system that runs a game-like test, which is completed by individuals using a mouse. The system then saves the individual's mouse movements in the form of a CSV file. This files are used for further analyzed using JMP Pro on how this data can be used for determining cognitive abilities via computing a metric called Fractal, and what conclusions can be drawn. In order to achieve comparable results, readings from two diverse age groups have been collected. The results using a total of 12 subjects are convincing in that the tool can be used to as a marker for detecting cognitive impairment.

Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>A população de idosos cresce rapidamente no Brasil. A prevalência de hipertensão arterial sistêmica (HAS) e distúrbios cognitivos é elevada nesta população. Testamos a hipótese de que a HAS reduz o desempenho cognitivos em idosos. Foram selecionamos idosos hipertensos e normotensos com idade &#8805; 60 < 80. O desempenho cognitivo foi avaliado pelo Cambridge Cognitive Examination Revised (CAMCOG-R), por subtestes do Wechsler Adult Intelligence Scale v.3 (WAIS III), além do Rey Auditory Verbal Learning Test (RAVLT), e o dos Trail Making Tests A/B (TMT-A/B). O desempenho cognitivo avaliado pelo escore global do CAMCOG-R e do QI estimado do WAIS III está reduzido nos idosos hipertensos mesmo quando controlado pela escolaridade, depressão, estado geral de saúde e qualidade de vida. O desempenho cognitivo em diversos domínios específicos controlados para a escolaridade, depressão, estado geral de saúde e qualidade de vida, e avaliados pelo CAMCOG-R, WAIS III, TMT-A e RAVLT também está reduzido nos idosos hipertensos. O presente estudo sugere que a HAS está associada ao declínio do desempenho cognitivo global em idosos. Notadamente, o desempenho das funções executivas está reduzido nos idosos hipertensos. Especula-se que a HAS seja um fator de risco para o declínio progressivo do desempenho cognitivo e, portanto, para o desenvolvimento de demência.<br>The elderly population is growing rapidly in Brazil. The prevalence of hypertension and cognitive disorders is high in this population. We tested the hypothesis that hypertension is associated with decreased cognitive performance in the elderly. We selected normotensive and hypertensive subjects aged &#8805; 60 <80 years old. Cognition was assessed through Cambridge Cognitive Examination Revised (CAMCOG-R), subtests of the Wechsler Adult Intelligence Scale v.3 (WAIS III), the Rey Auditory Verbal Learning Test (RAVLT), and the Trail Making Tests A/B (TMT-A/B). The cognitive performance assessed by the CAMCOG-R global score and the estimated WAIS III. QI is reduced in elderly hypertensives even when controlled for education, depression, health status and quality of life. The cognitive performance in diverse cognitive domains assessed through CAMCOG-R, WAIS III, TMT-A e RAVLT is also reduced in elderly hypertensives when contolled for education, depression, health status and quality of life. These results suggest that hypertension is associated with reduced global cognitive performance in eldely hypertensives. Notably, executive functions are reduced in eldely hypertensives. We speculate that hypertension might be a risk factor for the progressive decline in cognitive function and, therefore, for the development of dementia.

In this thesis, the relationship between cognition and speech-in-noise recognition, in normally-hearing Swedish students, is examined. The Trail Making Test, hypothesized to measure a wide range of cognitive functions, including executive function and working memory, has been criticized for being a culturally biased measure, hence the need for a culturally unbiased version. A between-group experiment was conducted in which a non-semantically dependent version of the Trail Making Test was compared to the original Trail Making Test in order to test for psychometric equivalence. A total of 21 young normally-hearing Swedish students were given three tests: TMT or TMT (non-semantically dependent version), a Swedish Reading Span Task and a Swedish speech-in-noise recognition task. The B parts of the two Trail Making Test versions differed significantly and both were moderately to highly correlated to speech-in-noise and reading span performance. The results indicates that the original Trail Making Test is a more plausible index for executive function and strengthens the relationship between executive function, working memory and speech-in-noise recognition.

The aim of the study was to produce preliminary normative indications for the Trail Making Test and the Stroop Test, administered in English, on a non-clinical sample of black, Xhosa-speaking, unskilled individuals (N = 33), with an educational level of 11 – 12 years, in two age categories (18 –29 and 30 – 40 years). The sample was equally distributed for gender and level of education. Participants, who were required to have a basic proficiency in English, were from traditionally black township schools with relatively disadvantaged quality of education. Within-sample age and gender effects were investigated. There were no significant age effects on the Trail Making Test, whereas there was one significant difference between age groups on the Stroop Test with respect to the Color-Word task, and a result that strongly approached significance on the Word task, with the younger group performing better than the older group. There were no significant gender effects on the Trail Making Test, whereas there was one significant difference between genders on the Stroop Test with respect to the Word task, and a result that approached significance on the Color task, with females performing better than males. Normative indications for both measures were compared to available normative data on western populations with higher levels and more advantaged quality of education. This comparison revealed consistently poorer performances for both the Trail Making Test and the Stroop Test, confirming the need for localised normative datasets to facilitate accurate neuropsychological diagnoses on culturally disadvantaged individuals.

La notion de "fonctions exécutives" est complexe et revêt de multiples dimensions. Pour mesurer de façon objective et reproductible ces fonctions, nous disposons d'outils dont le Trail Making Test (TMT) est un exemple. Afin d'appréhender les performances au TMT dans ses deux formes A et B, les cliniciens s'appuient sur les indices B-A ou B/A, supposés refléter le poids du processus d'alternance. L'objectif de notre étude est d'une part, de vérifier la validité de l'utilisation du TMT en pratique clinique à partir de l'indice B-A, et d'autre part, d'évaluer si le procesus d'alternance est le seul impliqué dans cette épreuve. Les résultats montrent que l'indice B-A ne permet pas d'évaluer de manière univoque le coût de l'alternance entre les deux lexiques impliqués et ceci pour trois raisons : les différences de longueur et d'organisation spatiale entre les parties A et B du TMT ont un effet sur les temps de réalisation, au détriment de la partie B. De plus, le type de lexique influence les performances, le lexique alphabétique étant plus long d'accès que le lexique numérique. Enfin la partie B du TMT apparaît multifactorielle : les performances à cette épreuve sont liées aux performances à différentes tâches évaluant des aspects distincts de l'administrateur central. Celui-ci semble jouer un rôle important dans la recherche en mémoire à long terme impliquée par l'accès au lexique alphabétique, alors que la procédure d'alternance semble pouvoir être réalisée sans l'intervention d'un contrôle exécutif<br>The concept of executive functions is complex and includes various aspects. We can use different tools to get an objective and reproductible evaluation of these functions, including the TMT. TMT can be assessed in the two forms, A and B, and psychologists used B-A or B/A indexes which represent the switching procedures. The first aim of our study is to examine the validity of TMT used in clinical practice with the B-A index, and the second objective is to assess if only the switching process is included in this task. Results showed the B-A index does not allow a non equivocal evaluation of the switching cost for three reasons : length and spatial organization between part A and B and lexicon types are sufficient to induce significant time differences in test performances, affecting more the part B. In addition the type of lexicons influences the performances. TMT part B performances are linked to task, exploring various components of the CE. Central Executive seems to have an important part in long term memory research associated with alphabetical lexicon access whereas switching operation could be performed without the involvement of an executive control