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Journal articles on the topic 'Trajectoire de lanceur'

Author: Grafiati

Published: 13 April 2024

Last updated: 31 July 2025

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1

Maqueda, Francis. "L’angoisse du lanceur dans la trajectoire du poids." Santé mentale au Québec 14, no. 1 (2006): 45–53. http://dx.doi.org/10.7202/031487ar.

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Résumé Sur la base d'une psychothérapie intensive qu'il a faite avec un adolescent, psychothérapie qui s'est poursuivie durant 15 mois, à raison de 2 à 3 séances par semaine, l'auteur essaie de différencier la problématique d'une crise de la pathologie en évolution en cours de consultation. En alternance avec le matériel clinique, l'auteur utilise diverses notions théoriques qui permettent de comprendre ce matériel.

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2

Kida, T., K. Matsuzaki, I. Yokota, et al. "POS0875 LATENT TRAJECTORY MODELING OF PULMONARY ARTERY PRESSURE IN SYSTEMIC SCLEROSIS: A RETROSPECTIVE COHORT STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 732.2–733. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2192.

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BackgroundSystemic sclerosis (SSc) is an autoimmune disease that is characterized by systemic vasculopathy and fibrosis. Pulmonary hypertension (PH), defined as elevated pulmonary arterial pressure (PAP), is one of the leading causes of death of SSc1. In recent years, various therapies have been developed to target each of the pathogenesis of SSc – autoimmunity, vasculopathy, and fibrosis. Accordingly, treatment strategies based on risk stratification for PH progression are aspired; however, prediction of changes in PAP in diverse patients with SSc has not been established2.ObjectivesTo visual

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Duchemin, Marie-Hélène, Marianne Sytchkov, and Charles-Edouard Houllier-Guibert. "Conter son récit entrepreneurial pour apprendre de soi." Marché et organisations N° 53, no. 2 (2025): 145–63. https://doi.org/10.3917/maorg.053.0145.

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Cet article présente les premiers résultats empiriques d’une recherche en entrepreneuriat, menée avec une méthodologie ad hoc basée sur les apports issus de la narratologie. L’objectif de la recherche est d’éclairer le réel expérimenté par les entrepreneurs dans une approche processuelle de l’entrepreneuriat. La narration comme procédé a permis de considérer trois niveaux, l’entrepreneuriat, l’entreprise et l’entrepreneur, tandis que le recours au conte comme forme particulière de récit cristallise les apprentissages que les individus retirent de leur expérience. L’action entrepreneuriale ains

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SAWTSCHUK, Jérôme, Philippe GOURDAIN, Olivier DELZONS, Agathe LARZILLIÈRE, François QUENOT, and Thierry COÏC. "Quelles trajectoires de réhabilitation pour la décharge de l'Île d'Ouessant (29) ? Retour sur dix années de recherche-action." Naturae 2021, no. 22 (2021): 309–19. https://doi.org/10.5852/naturae2021a22.

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En 2009 était lancée l'étude préalable à la fermeture de la décharge de Penn ar Roc'h située en contexte de pelouse et de lande de hauts de falaises littorales. Des échanges entre le bureau d'étude en charge de l'étude environnementale et des universitaires de l'Université de Brest menant des travaux de recherche sur la restauration écologique permettent de lancer une réflexion pour une expérimentation d'ingénierie écologique (transferts de litière de lande et de fauche de pelouse). Lors des journées REVER 2 à Brest en 2010, une visite du site de la décharge est réalisée juste avant les t

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Hundert, Amos, Christy Woolcott, Jon Dorling, Britney Benoit, and Marsha Campbell-Yeo. "Classification of Individual Pain Response Trajectories Following Medically Indicated Heel Lances in Preterm Infants During Their NICU Admission." Clinical Journal of Pain 38, no. 3 (2021): 151–58. http://dx.doi.org/10.1097/ajp.0000000000001011.

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Quincy-Lefebvre, Pascale. "Les campagnes de presse : un creuset militant pour l'enfance. L'engagement d'Alexis Danan, reporter à Paris-Soir dans les années trente." Revue d’histoire de l’enfance « irrégulière » N° 13, no. 1 (2011): 25–43. http://dx.doi.org/10.3917/rhei.013.0025.

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Alexis Danan (1890-1979) est l'une des grandes figures médiatiques de la campagne contre les « bagnes pour enfants » dans la France des années trente. Le reporter n’est pas le premier ni le seul à écrire sur le sujet. Le nom du journaliste est celui que la mémoire de la réforme des établissements de correction a le plus conservé. En pleine période de lutte antifasciste et sous le Front populaire, des hommes et des femmes se mobilisent ; ils interpellent le pouvoir pour dénoncer le scandale et demander des réformes. Après avoir été un homme d'enquête, le journaliste Alexis Danan dénonce et inte

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Malham, M., C. Sejling, D. C. Wilson, V. Wewer, M. Fox, and N. H. Rod. "P1196 The impact of childhood adversity on the disease course in paediatric-onset IBD and immune-mediated inflammatory diseases: a population-based life-course study." Journal of Crohn's and Colitis 19, Supplement_1 (2025): i2171—i2172. https://doi.org/10.1093/ecco-jcc/jjae190.1370.

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Abstract Background Psychological and emotional stress can cause inflammation, leading to immune-mediated inflammatory diseases (IMID) and impact the disease course in adults with IBD but the relationship in children remains understudied. [1,2] In a population-based cohort study, we aimed to estimate the effect of childhood adversities on developing a severe disease course in paediatric-onset IBD (pIBD) and IMID (pIMID) Methods Using the Danish registries, we identified all individuals born between 1981 and 2001 who were diagnosed with pIMID before age 18 (defined as IBD [most common pIMID], a

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Laidlaw, Sheonad, and Emma Carduff. "29 Multi-disciplinary palliative care for men living with duchenne: a qualitative interview study." BMJ Supportive & Palliative Care 8, no. 3 (2018): 370.3–371. http://dx.doi.org/10.1136/bmjspcare-2018-mariecurie.29.

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BackgroundDuchenne muscular dystrophy (DMD) is an x-linked ultra-rare neuromuscular condition affecting 1 in 3600–6000 live male births.1 Individuals live with an exceptional illness trajectory of prolonged dwindling frailty and high symptom burden.2 While it is recognised that a co-ordinated multidisciplinary team approach may increase the survival of those with DMD and improve their quality of life (QoL)3 adults are receiving less comprehensive and co-ordinated care compared with those in the paediatric service.4AimTo investigate QoL in adults with DMD living in the West of Scotland (WoS).Me

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Soyunov, Alexej, Dmitry Kuzmin, Sergej Prokopov, Alexandr Golovin, and Raykhan Abdylmanova. "The analyses of physical and mechanical properties in the process of soil interaction with working elements of the cultivator of vibrating principle action." E3S Web of Conferences 539 (2024): 02034. http://dx.doi.org/10.1051/e3sconf/202453902034.

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The characteristics of the natural-climatic zone of the Omsk region are given and an analysis of the physical and mechanical properties of soils is carried out. A technical solution for cultivating the soil using the working parts of vibrating cultivator has been proposed. In the process of this research, the dependences of the trajectory movement of the vibratingtype lancet paw and its blades ends when interacting with the cultivated soil were established, and calculations of traction resistance were performed. The use of vibrating working body of the cultivator reduces traction resistance by

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Kwok, Kaitlyn, Neha Sati, Louis Dron, and Srinivas Murthy. "Data flow within global clinical trials: a scoping review." BMJ Global Health 7, no. 4 (2022): e008128. http://dx.doi.org/10.1136/bmjgh-2021-008128.

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ObjectiveTo document clinical trial data flow in global clinical trials published in major journals between 2013 and 2021 from Global South to Global North.DesignScoping analysisMethodsWe performed a search in Cochrane Central Register of Controlled Trials (CENTRAL) to retrieve randomised clinical trials published between 2013 and 2021 from The BMJ, BMJ Global Health, the Journal of the American Medical Association, the Lancet, Lancet Global Health and the New England Journal of Medicine. Studies were included if they involved recruitment and author affiliation across different country income

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Valletta, Enrico, and Martina Fornaro. "1000 giorni e poi altri 1000: perché e come gli interventi precoci devono proseguire." PAGINE ELETTRONICHE DI QUADERNI ACP 31, no. 6 (2024): 1. https://doi.org/10.53141/peqacp.2024.6.am1.

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1000 days and then 1000 days again: why and how early interventions must continue The first 1000 days, from conception to 2 years of age, are now considered a key period for early childhood development, being crucial for physical growth and brain development in children. However, as now highlighted in the series of two papers published in the Lancet and dedicated to the Early Childhood Development, attention must continue in the next 1000 days of life, the period between 2 and 5 years of age. This time is important to consolidate the investments and achievements in child growth and development

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Charyate, Abdelilah. "Transition psychosociale dans le monde du travail, quel soutien et accompagnement ?" European Scientific Journal, ESJ 21, no. 8 (2025): 176. https://doi.org/10.19044/esj.2025.v21n8p176.

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Les trajectoires professionnelles et institutionnelles s’entremêlent dans un processus de socialisation identitaire, qui se manifeste par des tensions entre les attentes individuelles et les multiples dimensions du métier. Les transitions psychosociales peuvent engendrer diverses répercussions sur le bien-être psychologique et social des individus. L'objectif de ce papier est de se lancer dans une réflexion théorique qui considère les transitions psychosociales comme un processus professionnel important sur le lieu de travail. Il vise également à examiner les facteurs qui influencent la transf

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Beck, Douglas L., and Jedidiah J Grisel. "Cognitive screenings in otolaryngology? The time has come." Journal of Otolaryngology-ENT Research 14, no. 2 (2022): 56–60. http://dx.doi.org/10.15406/joentr.2022.14.00507.

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The demographics and communicative disorders which traverse aging, neurocognitive disorders and auditory problems are staggering. Lancet Public Health1 estimates 57 million people globally with dementia in 2019 and by 2050 there will be 153 million cases. People seek counsel from hearing care professionals (HCPs) because of complaints and observations such as they cannot understand speech-in-noise (SIN), and/or they are not sure what someone just said, and/or they cannot recall the details of a recent conversation. For many, the complaints and observations of hearing and listening disorders ar

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Brulois, Vincent. "S’engager pour engager : dynamique professionnelle des communicateurs internes." Revue Communication & professionnalisation, no. 7 (February 1, 2019): 10–28. http://dx.doi.org/10.14428/rcompro.v7i1.18163.

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Tous les ans, nombre d’entreprises lancent leur enquête d’engagement et les communicateurs internes sont sommés d’interroger des salariés, confrontés à des questions de sens. Partant du propos qu’« il faut s’engager pour engager », selon les mots d’un praticien, quelle sorte de professionnel engagé est ce praticien ? Celui-ci ne peut-il exercer son métier sans un investissement personnel fort ? De quoi est alors fait cet engagement ? Dans quelle mesure cet engagement influence-t-il la façon d’exercer son métier ? Telle est l’intrigue proposée et trois éclairages nous seront utiles pour la réso

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Zhang, Yujie, and Chaoran Yu. "Bibliometric Evaluation of Publications (2000-2020) on the Prognosis of Gastric Cancer." INQUIRY: The Journal of Health Care Organization, Provision, and Financing 58 (January 2021): 004695802110560. http://dx.doi.org/10.1177/00469580211056015.

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Background: Gastric cancer remains a global malignancy. The role of bibliometric analysis is increasingly valued. It is feasible and necessary to perform a bibliometric analysis to regurgitate studies in the prognosis of gastric cancer. Materials and methods: Web of Science was selected for the dataset resource. Articles published between 2000 and 2020 within the database of Web of Science Core Collection were included with predefined search terms. CiteSpace version 5.7.R1 and R software program version 4.0.3 were used for bibliometric analysis with parameters extrapolated from included studie

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Wang, Yingjie, Meiyi Liu, and Jiali Gao. "Enhanced receptor binding of SARS-CoV-2 through networks of hydrogen-bonding and hydrophobic interactions." Proceedings of the National Academy of Sciences 117, no. 25 (2020): 13967–74. http://dx.doi.org/10.1073/pnas.2008209117.

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Molecular dynamics and free energy simulations have been carried out to elucidate the structural origin of differential protein–protein interactions between the common receptor protein angiotensin converting enzyme 2 (ACE2) and the receptor binding domains of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [A. E. Gorbalenyaet al.,Nat. Microbiol.5, 536–544 (2020)] that causes coronavirus disease 2019 (COVID-19) [P. Zhouet al.,Nature579, 270–273 (2020)] and the SARS coronavirus in the 2002–2003 (SARS-CoV) [T. Kuikenet al., Lancet 362, 263–270 (2003)] outbreak. Analysis of the dy

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Bilyk, Artem, and Yaroslav Kashuba. "Threat factors from Lancet-type adversary UAVs and means of engineering protection against them, including the use of pre-detonation screens." Military Technical Collection, no. 31 (December 23, 2024): 71–82. https://doi.org/10.33577/2312-4458.31.2024.71-82.

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The article analyzes the known parameters of the Russian Lancet-type unmanned aerial vehicles and the threats they pose to military equipment and facilities. Formulas and calculation parameters of damage factors are presented. The mechanisms of destruction of protective materials under the action of these factors were analyzed. It is shown that the main safety during the detonation of the warhead is provided by the cumulative jet. Calculations of engineering defense systems to increase the survivability of military equipment and structures were carried out. It has been proven that shelters sho

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Ba, Hongjun, Lili Zhang, Xiufang He, and Shujuan Li. "Knowledge Mapping and Global Trends in the Field of the Objective Structured Clinical Examination: Bibliometric and Visual Analysis (2004-2023)." JMIR Medical Education 10 (September 30, 2024): e57772. http://dx.doi.org/10.2196/57772.

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Background The Objective Structured Clinical Examination (OSCE) is a pivotal tool for assessing health care professionals and plays an integral role in medical education. Objective This study aims to map the bibliometric landscape of OSCE research, highlighting trends and key influencers. Methods A comprehensive literature search was conducted for materials related to OSCE from January 2004 to December 2023, using the Web of Science Core Collection database. Bibliometric analysis and visualization were performed with VOSviewer and CiteSpace software tools. Results Our analysis indicates a cons

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Drummen, S., S. Balogun, L. Scheepers, et al. "AB0994 Exploring knee osteoarthritis pain trajectories and movement-evoked pain changes during a 24-week outdoor walking program (WALK)." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1622.1–1622. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4090.

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BackgroundExercise therapy is recommended as first line treatment for knee osteoarthritis (OA), but it remains to be sub-optimally applied (1). Movement-evoked pain is a potential barrier to exercise adherence, but recent evidence suggests that such pain can be improved by training (2). Walking programs are low-cost, easily adopted and can be performed outdoors which can minimize the risk of SARS-CoV-2 transmission when in a group (3).ObjectivesTo explore the acute pain trajectories of individuals with knee OA during a 24-week outdoor walking intervention. In addition, to explore the effect of

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Knaul, Felicia Marie, William E. Rosa, Lukas Radbruch, et al. "Improving access to palliative care to mitigate multi-dimensional breast cancer suffering." Journal of Clinical Oncology 42, no. 16_suppl (2024): e24084-e24084. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e24084.

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e24084 Background: The breast cancer (BC) divide persists as a global health and equity challenge. IARC data show that in low human development index (HDI) countries – 1/27 women is diagnosed with BC in their lifetime and 1/48 die from it. In very high HDI countries, BC is more common (1/12), but death is much less so (1/71). Hence, BC generates a substantial burden of serious health-related suffering (SHS) worldwide, and a particularly high and unmet demand for end-of-life care in poorer countries. This research links to three Lancet Commissions (LC): the forthcoming report of LC on BC, follo

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Boehm-Schnitker, Nadine. "Neo-Victorian Re-Imaginations of the Famine: Negotiating Bare Life through Transnational Memory." Neo-Victorian Studies 12, no. 1 (2019): 80–118. https://doi.org/10.5281/zenodo.3471028.

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Taking its cue from transcultural memory studies and the notion of travelling memory, this article analyses neo-Victorian famine novels, film and music with regard to these texts’ orientations towards the hungry body. The Great Famine in Ireland caused mass migration and resulted in both geographical and cultural re-orientations across a range of intertextual and intermedial products published in Ireland and in the diaspora, including Joseph O’Connor’s <em>Star of the Sea </em>(2002), which looks back to Emily Brontë’s <em>Wuthering Heights </em>(1847), and Paul Ly

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Santiago-Vieira, Carolina, Gustavo Velasquez-Melendez, Rita de Cássia Ribeiro Silva, Elizabete de Jesus Pinto, Maurício L. Barreto, and Leah Li. "Corrigendum to “Recent changes in growth trajectories: a population-based cohort study of over 5 million Brazilian children born between 2001 and 2014” [The Lancet Regional Health—Americas 2024; Volume 32, 100721, Published: March 27, 2024]." Lancet Regional Health - Americas 34 (June 2024): 100787. http://dx.doi.org/10.1016/j.lana.2024.100787.

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Coates, L., J. Ramírez, D. Mcgonagle, et al. "POS1540 EARLY SKIN AND EARLY ENTHESITIS RESPONSES IN PSORIATIC ARTHRITIS PATIENTS TREATED WITH GUSELKUMAB ASSOCIATE WITH LONG-TERM RESPONSE: POST HOC ANALYSIS THROUGH 2 YEARS OF A PHASE 3 STUDY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1137.1–1137. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2581.

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BackgroundGuselkumab (GUS), an IL-23p19 inhibitor, has demonstrated efficacy in psoriatic arthritis (PsA) across key Group for Research and Assessment of Psoriasis (PsO) and Psoriatic Arthritis (GRAPPA)-recommended domains[1,2]. Skin disease and enthesitis have been identified as disease manifestations with earlier response times than others[3].ObjectivesIn this analysis we: (a) Determined whether early skin and/or entheseal response predicts future response in other PsA domains; (b) Evaluated the trajectory for achieving skin/entheseal responses by 52 weeks (W) in patients (pts) without early

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Cheng, Yung-Ze, Tzu-Han Lai, Tsair-Wei Chien, and Willy Chou. "Evaluating cluster analysis techniques in ChatGPT versus R-language with visualizations of author collaborations and keyword cooccurrences on articles in the Journal of Medicine (Baltimore) 2023: Bibliometric analysis." Medicine 102, no. 49 (2023): e36154. http://dx.doi.org/10.1097/md.0000000000036154.

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Background: Analyses of author collaborations and keyword co-occurrences are frequently used in bibliographic research. However, no studies have introduced a straightforward yet effective approach, such as utilizing ChatGPT with Code Interpreter (ChatGPT_CI) or the R language, for creating cluster-oriented networks. This research aims to compare cluster analysis methods in ChatGPT_CI and R, visualize country-specific author collaborations, and then demonstrate the most effective approach. Methods: The research focused on articles and review pieces from Medicine (Baltimore) published in 2023. B

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Bulatov, K. V., V. P. Zhukov, E. V. Bratygin, N. A. Tomilov, and V. A. Menshchikov. "Investigation of Pobeda furnace bubbling zone physics using cold modeling method Part 3. The hydro-gas dynamics of combined blowing of liquid by gas using bottom and lateral lances." Izvestiya. Non-Ferrous Metallurgy 1, no. 1 (2023): 26–38. http://dx.doi.org/10.17073/0021-3438-2023-1-26-38.

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Hydro-gas regularities of liquid combined blowing by gas were studied using cold modeling method at Archimedes criterion for lateral Arl = 12÷120 and bottom blowing Arb = 5÷60 simulating Pobeda bubbling unit. The blowing was performed simultaneously by bottom lance vertically fixed in centre of reactor and by the lateral lance which was attached at an angle 5° to the horizontal axis. The quantitative estimation of instantaneous and average circulation velocities (Vav) of liquid flow elements in different bath areas, depending on the location of blowing zone and Archimedes criterion, was perfor

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Harty, T., D. Dahly, S. Costelloe, M. O’ Shaughnessy, and S. Harney. "AB0335 INCIDENT CHRONIC KIDNEY DISEASE IN PATIENTS WITH RHEUMATOID AND PSORIATIC ARTHRITIS – A COMPARATIVE ANALYSIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1350.2–1351. http://dx.doi.org/10.1136/annrheumdis-2023-eular.5818.

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BackgroundPatients with inflammatory joint conditions have a high prevalence of comorbidities including chronic kidney disease (CKD) [1]. The data pertaining to CKD in rheumatoid arthritis (RA) is limited [2], however and its association with psoriatic arthritis (PsA) remains unclear. Renal disease in RA and PsA is clinically important as it can lead to restrictions in the management of the primary disease, and is also associated with increased all-cause morbidity and mortality [3].ObjectivesTo determine and compare the rate of incident CKD in patients with rheumatoid and psoriatic arthritis a

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Ibrahim, F. A. E., and S. Sebastian. "P0365 The evolution of Geldof fistula class in patients with Crohn’s disease perianal fistula." Journal of Crohn's and Colitis 19, Supplement_1 (2025): i839. https://doi.org/10.1093/ecco-jcc/jjae190.0539.

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Abstract Background Progressing the evaluation and management of Perianal fistulizing Crohn’s disease ( CD-pAF ) , an aggressive phenotype of CD , is one of the key unmet needs in Inflammatory Bowel Disease (IBD). There is sub-optimal understanding of the behavior of CD-pAF with some patients having rapid velocity of disease progression needing radical surgery such as proctectomy or diverting stoma. More recently, a practical patient-centric classification has been developed recently by Geldof et al has been used to classify patients underpinned by the behavior of CD-pAF(1). We aimed to evalua

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Jayadi, Akhmad, Dwi Handoko, Rizka Permata, Atika Arpan, and Dian Meilantika. "IMPLEMENTASI PATH SMOOTHING MENGGUNAKAN ALGORITMA GRADIENT DESCENT MENGGUNAKAN SIMULASI V-REP." HOAQ (High Education of Organization Archive Quality) : Jurnal Teknologi Informasi 15, no. 2 (2024): 107–15. https://doi.org/10.52972/hoaq.vol15no2.p107-115.

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Perkembangan teknologi robot mobile telah mengubah berbagai sektor industri, dan salah satu tantangan utama dalam pengoperasian robot mobile adalah perencanaan jalur (path planning). Jalur yang direncanakan sering kali tidak mempertimbangkan gerakan robot, terutama saat menghadapi belokan tajam yang dapat menyebabkan inefisiensi gerak robot, untuk mengatasi hal ini, teknik path smoothing digunakan untuk mereduksi ketajaman belokan, memungkinkan robot bergerak lebih lancar dan efisien. Salah satu algoritma yang digunakan dalam path smoothing adalah Gradient Descent, yang secara iteratif memperb

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Peyrin-Biroulet, L., E. Louis, T. Hisamatsu, et al. "P736 Factors associated with partial Mayo Clinic Score over time in patients with Ulcerative Colitis treated with filgotinib in the phase 2b/3 SELECTION trial." Journal of Crohn's and Colitis 17, Supplement_1 (2023): i866. http://dx.doi.org/10.1093/ecco-jcc/jjac190.0866.

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Abstract Background Responses to ulcerative colitis (UC) treatments vary considerably between individuals, and factors associated with a stable response are not well defined. Filgotinib (FIL) is an oral, Janus kinase 1 preferential inhibitor approved in the EU and the UK as a UC therapy. We aimed to identify factors associated with partial Mayo Clinic Score (pMCS) over time in FIL-treated patients with UC in the phase 2b/3 SELECTION trial (NCT02914522). Methods In SELECTION, adults with moderately to severely active UC received FIL 200 mg (FIL200), FIL 100 mg (FIL100) or placebo once daily for

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Imran Majeed, Syed Muhammad, and Rehma Ahsan Gilani. "Covid-19: Navigating Scientific Uncertainty." Life and Science 1, no. 3 (2020): 2. http://dx.doi.org/10.37185/lns.1.1.127.

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   Alvin Toffler once wrote: "The illiterate of the 21st century will not be those who cannot read and write, but those who cannot learn, unlearn, and relearn." This pandemic has proven his statement correct. The global academic community has learned a completely new culture of research, with torrents of data being released daily on preprint servers1,2 and dissected on platforms such as Slack and Twitter before formally peer reviewed. Fifty-five thousand viral genomes sequences of hCoV-19 shared on GISAID platforms to date3 that have been analyzed instantaneously, by a phalan

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Vincent, *Kathleen Frances, Angel J. Cho, and Ken Solt. "ACTIVATING DOPAMINE NEURONS IN THE VENTRAL TEGMENTAL AREA FACILITATES COGNITIVE RECOVERY FOLLOWING DEXMEDETOMIDINE- INDUCED LOSS OF CONSCIOUSNESS IN RATS." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i270. https://doi.org/10.1093/ijnp/pyae059.477.

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Abstract Background As the number of people requiring general anesthesia continues to increase (Meara et al., 2015), understanding how consciousness and cognition are restored following drug-induced loss of consciousness becomes increasingly important. Rodent studies indicate that dopaminergic neurons in the ventral tegmental area (VTA) are critically involved in restoring arousal following general anesthesia (Vincent and Solt, 2023). Whether these circuits contribute to cognitive recovery, however, is unknown. Recently, a novel cognitive recovery testing paradigm for rodents was established u

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Aprillia, Yuna Trisuci, Asyifa Robiatul Adawiyah, Kusmayra Ambarwati, and Faradibha Tenrilemba. "Factors Associated with Breastfeeding Self-Efficacy and COVID-19 Pandemic Anxiety in Post Partum Mothers." Jurnal Kesehatan Masyarakat 20, no. 1 (2024): 47–57. https://doi.org/10.15294/kemas.v20i1.45047.

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Admasu, J., Egata, G., Bassore, D. G., Feleke, F. W. (2022). Effect of maternal nutrition education on early initiation and exclusive breast-feeding practices in south Ethiopia: a cluster randomised control trial. Journal of Nutritional Science, 11. https://doi.org/10.1017/JNS.2022.36American Dietetic Association. (2009). Position of the American Dietetic Association: Promoting and Supporting Breastfeeding. Journal of the American Dietetic Association, 109(11), 1926–1942. https://doi.org/10.1016/J.JADA.2009.09.018Badan Pusat Statistik. (2021). Potret Sensus Penduduk 2020 Menuju Satu Data Kepen

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Shen, *Cheng Che, Ya-Han Hu, and Ya-Mei Bai. "A STUDY ON USING CHIEF COMPLAINTS OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND BIPOLAR DISORDER FOR VOICE ANALYSIS AND TEXT MINING TO DIFFERENTIATE BETWEEN THE TWO." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i284—i285. https://doi.org/10.1093/ijnp/pyae059.504.

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Abstract Background Major depressive disorder (MDD) and bipolar disorder are common psychiatric mood disorders with distinct clinical trajectories and treatment approaches. Misdiagnosis occurs when bipolar disorder manifests as depression, leading to treatment resistance in MDD. Currently, no method can reliably differentiate between depressive episodes in MDD and bipolar disorder. This study employs text mining, audio analysis, and data mining to develop predictive models for distinguishing these conditions. Aims & Objectives The study aims to: 1. Collect data from individuals diagnosed w

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Dreo, B., B. Prietl, S. Kofler, et al. "AB0019 RITUXIMAB TREATMENT DOES NOT ALTER EXPRESSION OF CO-STIMULATION MARKER CD19 ON B CELLS IN SYSTEMIC SCLEROSIS PATIENTS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1144.2–1145. http://dx.doi.org/10.1136/annrheumdis-2022-eular.768.

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BackgroundCD19 is a membrane glycoprotein interacting with different surface molecules like the B cell receptor (BCR) and is crucial for antigen-independent development as well as immunoglobulin-induced activation of B cells.[1] Alterations in this signalling pathway can incline autoantibody production and systemic autoimmunity in humans. Rituximab (RTX), a CD20 antagonist appears to be an effective candidate in the treatment of different autoimmune diseases that are partly driven by autoreactive B cells, such as systemic sclerosis (SSc).[2] It has been speculated that RTX might work not only

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Silberstein, Alice, Mark A. Fiala, Sarah Kelley, Mark A. Schroeder, Keith E. Stockerl-Goldstein, and Ravi Vij. "Financial Toxicity Among Patients with Multiple Myeloma." Blood 138, Supplement 1 (2021): 4027. http://dx.doi.org/10.1182/blood-2021-153653.

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Abstract Background: Treatment-related financial burden, or financial toxicity, can detract from mental health and quality of life and can lead patients to alter their care to offset treatment costs. In doing so, these patients compromise adherence which can contribute to disparities (Zafar Oncologist 2013). Among cancers, multiple myeloma treatment is particularly costly due to use of expensive, novel agents, often in combination, and for extended durations. One study found that patients with myeloma frequently reported financial toxicity and used coping strategies, including borrowing money

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Bartlett, S. J., O. Schieir, M. F. Valois, et al. "OP0308-HPR MORE THAN HALF OF RA PATIENTS WITH A LIFETIME HISTORY OF MOOD DISORDERS WERE ANXIOUS AND DEPRESSED DURING THE COVID-19 PANDEMIC: RESULTS FROM THE CANADIAN EARLY COHORT (CATCH) STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 204.2–204. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2411.

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BackgroundA growing number of studies indicate the considerable mental health impacts of the prolonged COVID-19 pandemic in the general population as chronic stress is a risk factor for the development of depression and anxiety. Mood disorders are more prevalent in RA and a history of anxiety or depressive disorders increases the risk of recurrence in the future.ObjectivesTo compare trends in prevalence of anxiety and depressive symptoms, prior to and during the COVID-19 pandemic in RA patients with and without a lifetime history of mood disorders.MethodsData were from RA patients diagnosed an

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Cocciardi, Sibylle, Nina Weiß, Maral Saadati, et al. "The Genomic Landscape and Its Clinical Implication in NPM1-Mutated AML Patients: A Study within the AMLSG 09-09 Clinical Trial." Blood 142, Supplement 1 (2023): 4311. http://dx.doi.org/10.1182/blood-2023-185566.

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Background: Mutations in the Nucleophosmin 1 gene ( NPM1 mut ) represent one of the most common genetic lesions in acute myeloid leukemia (AML).Based on its characteristic clinico-pathologic features, NPM1 mutAML has been recognized as a distinct entity among the category “AML with recurrent genetic abnormalities”. According to the ELN 2022 genetic risk-stratification, NPM1 mut AML, in the absence of FLT3-ITD mutation, is associated with a favorable prognosis. However, a significant proportion of these patients (pts) relapse after intensive therapy suggesting that other co-mutations may have a

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Tyanova, Stefka, Tao Xu, Mellissa Williamson, et al. "Lab-Based Response Assessment Algorithm Recapitulates Investigator's Response Assessment in the Phase 3 Bellini Trial." Blood 138, Supplement 1 (2021): 4758. http://dx.doi.org/10.1182/blood-2021-147713.

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Abstract Background: Real-world data (RWD) derived from electronic health records are becoming increasingly important for deriving insights from clinical practice to complement findings from clinical trials. Response to treatment in multiple myeloma (MM) is assessed using the International Myeloma Working Group (IMWG) response criteria based on MM-specific laboratory measures (i.e. monoclonal [M] protein in serum and urine, free light chain [FLC] levels), as well as radiological images and bone marrow (BM) investigations when appropriate. As healthcare providers do not routinely collect all th

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Hong, Fangxin, Andrew M. Evens, Paul J. Novotny, et al. "A Longitudinal Toxicity over Time (ToxT) Analysis of Bortezomib When Added to Bendamustine-Rituximab (BR) in Previously Untreated High Risk (HR) Follicular Lymphoma (FL) from in E2408." Blood 132, Supplement 1 (2018): 4157. http://dx.doi.org/10.1182/blood-2018-99-117249.

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Abstract Background: Bortezomib has efficacy in follicular lymphoma (FL). Though generally well tolerated, it is associated with a few known toxicities, including neurotoxicity. As a chronically administered agent, it is important to investigate the tolerability of bortezomib over time as a single agent and in combination with chemotherapy. The current method of summarizing adverse events (AEs) -focusing on the maximum grade and reporting only grade 3 or higher incidences- fails to capture toxicity that evolves over time or chronic low grade AEs that may occur at significant expense to patient

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Barraclough, Allison, Edward Yoo, Chan Y. Cheah, et al. "The 'Real World' Uptake and Prognostic Impact of GELF in Newly Diagnosed Follicular Lymphoma: An Australasian Alliance Initiative." Blood 134, Supplement_1 (2019): 3986. http://dx.doi.org/10.1182/blood-2019-129294.

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Background The time to treatment initiation is determined by tumour burden in patients with follicular lymphoma (FL). The Groupe d'Etude des Lymphomes Folliculaires ('GELF') criteria, defined in the pre-rituximab era, are commonly used to assess tumour burden.2 Patients must meet ≥1 of the following criteria to be considered "high" tumour burden according to GELF: any tumour mass >7 cm; ≥ 3 nodal sites (each >3 cm); B symptoms; splenomegaly; compression syndrome; pleural/peritoneal effusion; leukemic phase or cytopenias. Low tumour burden FL is often excluded from clinical trials, based

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Sidana, Surbhi, Gita Thanarajasingam, Joan Griffin, et al. "Patient Experience of Chimeric Antigen Receptor (CAR)-T Cell Therapy Vs. Stem Cell Transplant: Longitudinal Patient Reported Adverse Events, Cognition and Quality of Life." Blood 134, Supplement_1 (2019): 794. http://dx.doi.org/10.1182/blood-2019-121715.

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Introduction: With the expanding use of CAR-T cell therapy, which is associated with serious adverse effects (AEs), there is a need to characterize the patient's experience over time to guide patient/provider education, and help optimize symptom management. This study reports on longitudinal evaluation of patient-reported quality of life (QOL) and symptom burden of CAR-T cell therapy compared with established forms of cellular therapy i.e autologous stem cell transplant (autoSCT) and allogeneic SCT (alloSCT). Methods: Patients with hematologic malignancies were prospectively recruited in three

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Akmal, Yenina, Hikmah, Astari, and Ichtineza Halida Hardono. "Preparing for Parenthood; Parenting Training Module on six Child Development Aspect in East Jakarta." JPUD - Jurnal Pendidikan Usia Dini 13, no. 2 (2019): 371–85. http://dx.doi.org/10.21009/jpud.132.12.

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 The age period of 0-8 years is the most important moment for every human being to develop all the developmental features supported by parents at home and teachers / tutors at the Early Childhood Education Institute (ECE). In parenting, six main aspects must be known and applied by each parent. Lack of education, nutritional knowledge, care and care, and aspects of clean-living habits in the family can have an impact on children's growth and development processes. This study aims to develop a module 6 aspects of child development for parental guidance. This study uses a research and deve

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Hong, Fangxin, Gita Thanarajasingam, Stephen M. Ansell, et al. "Longitudinal Adverse Event Assessment of the Combination of Ipilimumab, Nivolumab and Brentuximab Vedotin in Relapsed / Refractory Hodgkin Lymphoma: A Trial of the ECOG-ACRIN Cancer Research Group (E4412: Arms A-F)." Blood 132, Supplement 1 (2018): 623. http://dx.doi.org/10.1182/blood-2018-99-119372.

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Abstract Background: Checkpoint blockade therapies (CBT) have substantially improved outcomes for patients in a variety of cancers. However, they are associated with a unique spectrum of immune-related adverse events (AEs). Additionally, unlike standard chemotherapy, many patients (pts) remain on CBT for prolonged periods of time, thus immune-related symptomatic AEs may be chronic or low grade therefore important to capture long term tolerability when used as a single agent or in combination with chemotherapy. In this study, we applied the Toxicity over Time (ToxT) analytic approach (Thanaraja

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Капранов, Олександр. "The Framing of Dementia in Scientific Articles Published in ‘Alzheimer’s and Dementia’ in 2016." East European Journal of Psycholinguistics 3, no. 2 (2016): 32–48. http://dx.doi.org/10.29038/eejpl.2016.3.2.kap.

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The present article involves a qualitative study of the framing of dementia in ‘Alzheimer’s and Dementia’, the Journal of the Alzheimer’s Association, published in 2016. The aim of this study is to elucidate how dementia is framed qualitatively in the corpus consisting of scientific articles involving dementia published in ‘Alzheimer’s and Dementia’. The results of the qualitative analysis indicate that dementia is represented in ‘Alzheimer’s and Dementia’ in 2016 as the frames associated with gender, age, costs, caregiver and care-recipients, disability and death, health policy, spatial orien

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Bukhari, Syeda Tehmina, Muhammad Rafiq-uz-Zaman, and Sumera Bano. "Analysing the Impact of Education Policies and Their Implementation on the School Education System in Punjab, Pakistan." Inverge Journal of Social Sciences 4, no. 1 (2025): 98–110. https://doi.org/10.63544/ijss.v4i1.136.

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In Punjab, Pakistan, a province whose educational outcomes are pivotal to national development, the school system continues to struggle with significant challenges in access, quality, and equity. Despite a long history of ambitious education policies, a persistent and critical gap exists between policy intentions and their practical implementation, leaving many students without quality learning opportunities and teachers without adequate support. This narrative review analyzes the landscape of education policy and reform since 2001, synthesizing a wide body of evidence from policy documents, p

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CERF, Max. "Trajectoires spatiales - Étagement de lanceur." Systèmes aéronautiques et spatiaux, November 2023. http://dx.doi.org/10.51257/a-v1-trp4065.

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Kolunsarka, Iiris, Michael Beets, Mikko Huhtiniemi, and Timo Jaakkola. "212 Multi-trajectory analysis of changes in physical activity, BMI and cardiorespiratory fitness in adolescence." European Journal of Public Health 34, Supplement_2 (2024). http://dx.doi.org/10.1093/eurpub/ckae114.089.

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Abstract Purpose Over the past four decades, the worldwide prevalence of obesity has nearly tripled, with childhood obesity being now more common than ever. Furthermore, children and adolescents with overweight or obesity are at a higher risk of retaining this condition into adulthood (Lobstein et al., 2015). Previous studies have shown that larger increase in body mass index (BMI) during adolescence is associated with less improvements in cardiorespiratory fitness (CRF) and steeper decline in moderate to vigorous physical activity (MVPA) (Kolunsarka et al., 2021). However, the trajectories of

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De Looze, Céline, Wilby Williamson, Naiara Demnitz, Deirdre O’Connor, Belinda Hernández, and Rose Anne Kenny. "Physical Function, An Adjunct to Brain Health Score for Phenotyping Cognitive Function Trajectories in Older Age: Findings From The Irish Longitudinal Study on Ageing (TILDA)." Journals of Gerontology: Series A, January 29, 2022. http://dx.doi.org/10.1093/gerona/glac024.

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Abstract Background Evidence is limited regarding the cumulative effect of risk factors on cognitive decline and the added value of physical function for cognitive function trajectory stratification. We operationalize 13 modifiable dementia risk factors in a scoring system and investigate the relationship between this brain health score, combined with simple measures of physical function, and risk of cognitive decline. Methods Population-based cohort study of persons aged 50 and older from the Irish Longitudinal Study on Ageing without a history of dementia at baseline who underwent repeated n

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SAWTSCHUK, Jérôme, Philippe GOURDAIN, Olivier DELZONS, Agathe LARZILLIÈRE, François QUENOT, and Thierry COÏC. "Quelles trajectoires de réhabilitation pour la décharge de l’Île d’Ouessant (29) ? Retour sur dix années de recherche-action." Naturae, no. 22 (October 20, 2021). http://dx.doi.org/10.5852/naturae2021a22.

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En 2009 était lancée l’étude préalable à la fermeture de la décharge de Penn ar Roc’h située en contexte de pelouse et de lande de hauts de falaises littorales. Des échanges entre le bureau d’étude en charge de l’étude environnementale et des universitaires de l’Université de Bretagne occidentale menant des travaux de recherche sur la restauration écologique permettent de lancer une réflexion pour une expérimentation d’ingénierie écologique (transferts de litière de lande et de fauche de pelouse). Lors des journées REVER 2 à Brest en 2010, une visite du site de la décharge est réalisée juste a

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Damigou, E., C. Chrysohoou, F. Barkas, et al. "Adherence to a sustainable diet, measured via the EAT-Lancet Index, predicts incident short-term and long-term cardiovascular disease incidence: the ATTICA study (2002-2022)." European Heart Journal 45, Supplement_1 (2024). http://dx.doi.org/10.1093/eurheartj/ehae666.2936.

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Abstract Background/Introduction The World Heart Federation has estimated that air pollution was the second most fatal modifiable risk factor for cardiovascular disease (CVD), causing approximately 5 million CVD deaths in 2021. Diets and food systems can affect the environment; however, research scarcely focuses on the association between planet-healthy dietary habits and CVD risk. Purpose The purpose of this study was to evaluate the adherence to a sustainable diet and CVD incidence during 20 years of follow-up. Methods Participants initially free-of-CVD from the ATTICA study were used (n=1,9

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