Academic literature on the topic 'Transciptomic analysis'

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Journal articles on the topic "Transciptomic analysis"

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Kim, Kwang-Ho, and Dae-Weon Lee. "Transciptomic Analysis of Larval Fat Body of Plutella xylostella under Low Temperature." Korean Journal of Environmental Agriculture 38, no. 4 (2019): 296–306. http://dx.doi.org/10.5338/kjea.2019.38.4.40.

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Orekhov, A., Y. Oishi, N. Nikiforov, et al. "Transciptome analysis revealed inflammatory genes responsible for foam cell formation." Atherosclerosis 275 (August 2018): e116. http://dx.doi.org/10.1016/j.atherosclerosis.2018.06.329.

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Wiwanitkit, Somsri, and Viroj Wiwanitkit. "Nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1: Transciptomics approach." Annals of Tropical Medicine and Public Health 10, no. 4 (2017): 1081. http://dx.doi.org/10.4103/1755-6783.196696.

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Cui, Jun, Shikai Liu, Bing Zhang, et al. "Transciptome Analysis of the Gill and Swimbladder of Takifugu rubripes by RNA-Seq." PLoS ONE 9, no. 1 (2014): e85505. http://dx.doi.org/10.1371/journal.pone.0085505.

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Hotinski, Anya K., Karen M. Lower, and Bryone J. Kuss. "Somatic MDC1 Mutation in Putative Pre-Leukaemic Stem Cell of a Biclonal Case of Chronic Lymphocytic Leukaemia." Blood 132, Supplement 1 (2018): 5534. http://dx.doi.org/10.1182/blood-2018-99-115704.

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Abstract Chronic lymphocytic leukaemia (CLL) is an inherently heterogeneous disease in which founding lesions and cell of origin remain a subject of debate. This case of truly biclonal CLL provides evidence of the presence of a pre-leukaemic stem cell, supporting other lines of evidence that pathogenic genetic and epigenetic lesions in CLL arise early in haematopoiesis. An individual with trisomy 12 containing CLL, present at a frequency of 30%, was identified. Two distinct CD5/19-positive CLL clones were separated by flow cytometry, based on bimodal expression of CD49d. Each leukaemic clone w
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Babenko, Vladislav V., Rustam H. Ziganshin, Christoph Weise, et al. "Novel Bradykinin-Potentiating Peptides and Three-Finger Toxins from Viper Venom: Combined NGS Venom Gland Transcriptomics and Quantitative Venom Proteomics of the Azemiops feae Viper." Biomedicines 8, no. 8 (2020): 249. http://dx.doi.org/10.3390/biomedicines8080249.

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Feae’s viper Azemipos feae belongs to the Azemiopinae subfamily of the Viperidae family. The effects of Viperidae venoms are mostly coagulopathic with limited neurotoxicity manifested by phospholipases A2. From A. feae venom, we have earlier isolated azemiopsin, a novel neurotoxin inhibiting the nicotinic acetylcholine receptor. To characterize other A. feae toxins, we applied label-free quantitative proteomics, which revealed 120 unique proteins, the most abundant being serine proteinases and phospholipases A2. In total, toxins representing 14 families were identified, among which bradykinin-
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Branca, Enrica, Giovanna Carrà, Isabella Russo, Massimo Terzolo, Angelo Guerrasio, and Alessandro Morotti. "In-Silico Transcriptome Analyses of Hemostasis Triggers in Inflamed Vs Normal Mucosa of IBD Patients." Blood 136, Supplement 1 (2020): 19–20. http://dx.doi.org/10.1182/blood-2020-136706.

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Background:inflammatory bowel disease (IBD) is characterized by chronic inflammation associated with an increased tendency to thrombosis and thromboembolic complications. The underlying mechanisms of VTE are not yet fully understood. Several studies reported different expressions of circulating procoagulant factors or fibrinolysis inhibitors in IBD. Others linked podoplanin overexpression with thrombosis, hypercoagulability, and increased risk of VTE. Here, we aimed to identify, among genes able to trigger thrombosis, those aberrantly expressed in IBD samples as compared with matched normal mu
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Ribeiro, Edna, Mariana Delgadinho, and Miguel Brito. "Environmentally Relevant Concentrations of Bisphenol A Interact with Doxorubicin Transcriptional Effects in Human Cell Lines." Toxics 7, no. 3 (2019): 43. http://dx.doi.org/10.3390/toxics7030043.

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The worldwide production of synthetic chemicals, including endocrine disruptor chemicals (EDCs), such as Bisphenol A (BPA) has increased significantly in the last two decades. Human exposure to BPA, particularly through ingestion, is continuous and ubiquitous. Although, considered a weak environmental estrogen, BPA can induce divergent biological responses through several signaling pathways, including carcinogenesis in hormone-responsive organs. However, and despite the continuous increase of tumor cell-resistance to therapeutic drugs, such as doxorubicin (DOX), information regarding BPA drug
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de Jong, Madelon M. E., Zoltan Kellermayer, Natalie Papazian, et al. "Single Cell Transcriptomic Analysis of the Multiple Myeloma Bone Marrow Identifies a Unique Inflammatory Stromal Cell Population Associated with TNF Signaling." Blood 134, Supplement_1 (2019): 690. http://dx.doi.org/10.1182/blood-2019-123012.

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Background: In multiple myeloma, tumor cell survival, disease progression and therapy response are influenced by signals derived from the non-malignant bone marrow niche. This notwithstanding, a detailed in-vivo definition of the cells that define the multiple myeloma niche is lacking. Mesenchymal stromal cells are important niche constituents. Recent progress made with single cell transciptomics suggests that mesenchymal stromal cells are a dynamic population of cells that can exist as several subsets with functionally distinct activation and differentiation profiles. Aim: To identify mesench
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Visani, Giuseppe, Francesco Di Raimondo, Felicetto Ferrara, et al. "Low-Dose Lenalidomide Plus Low Dose Cytarabine Induce Complete Remission That Can Be Predicted By Genetic Profiling In Very Elderly Acute Myeloid Leukemia Patients." Blood 122, no. 21 (2013): 496. http://dx.doi.org/10.1182/blood.v122.21.496.496.

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Abstract Outcome for older patients with acute myeloid leukemia (AML) is extremely poor. Intensive induction chemotherapy is often unsuitable. In this phase II study we tested, for the first time, the efficacy of a novel combination therapy with low-dose lenalidomide plus low-dose cytarabine. Further, based on the hypothesis that genetic features might influence treatment response, we aimed at identifying a possible biomarker by studying the global gene expression profiles (GEP). We designed a prospective phase II study to assess the efficacy of the concomitant administration of low-dose lenal
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Dissertations / Theses on the topic "Transciptomic analysis"

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Xu, Guorong. "RNA CoMPASS: RNA Comprehensive Multi-Processor Analysis System for Sequencing." ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1531.

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The main theme of this dissertation is to develop a distributed computational pipeline for processing next-generation RNA sequencing (RNA-seq) data. RNA-seq experiments generate hundreds of millions of short reads for each DNA/RNA sample. There are many existing bioinformatics tools developed for the analysis and visualization of this data, but very large studies present computational and organizational challenges that are difficult to overcome manually. We designed a comprehensive pipeline for the analysis of RNA sequencing which leverages many existing tools and parallel computing technology
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Toueni, Maoulida. "Étude de l'interaction entre Verticillium alfalfae et Medicago truncatula." Thesis, Toulouse, INPT, 2014. http://www.theses.fr/2014INPT0097/document.

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La verticilliose de la luzerne cultivée (Medicago sativa L.) est une maladie de flétrissement vasculaire causée par le champignon du sol Verticillium alfalfae. C’est une des maladies les plus dévastatrices et les plus difficiles à contrôler. Les symptômes sont un jaunissement des feuilles suivi de flétrissement et défoliation. Les structures de dormance produites en fin de cycle de maladie constituent une source de contamination pour plusieurs années. Aucun traitement fongicide n’est efficace, la seule méthode de contrôle reste la production de variétés résistantes. En raison de sa nature tétr
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