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Relevant bibliographies by topics / Transcription factor IIIA-interacting protein

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Academic literature on the topic 'Transcription factor IIIA-interacting protein'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Transcription factor IIIA-interacting protein"

1

Moreland, R. J., M. E. Dresser, J. S. Rodgers, et al. "Identification of a transcription factor IIIA-interacting protein." Nucleic Acids Research 28, no. 9 (2000): 1986–93. http://dx.doi.org/10.1093/nar/28.9.1986.

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Shastry, B. S. "Transcription factor IIIA (TFIIIA) in the second decade." Journal of Cell Science 109, no. 3 (1996): 535–39. http://dx.doi.org/10.1242/jcs.109.3.535.

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Transcription factor IIIA is a very extensively studied eukaryotic gene specific factor. It is a special member of the zinc finger family of nucleic acid binding proteins with multiple functions. Its N-terminal polypeptide (280 amino acid residue containing peptide; finger containing region) carries out sequence specific DNA and RNA binding and the C-terminal peptide (65 amino acid residue containing peptide; non-finger region) is involved in the transactivation process possibly by interacting with other general factors. It is a unique factor in the sense that it binds to two structurally diff

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Wyszko, E., M. Radłowski, S. Bartkowiak, and M. Z. Barciszewska. "Maize TF IIIA--the first transcription factor IIIA from monocotyledons. Purification and properties." Acta Biochimica Polonica 44, no. 3 (1997): 579–89. http://dx.doi.org/10.18388/abp.1997_4406.

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Purification and properties of transcription factor IIIA (TF IIIA) from maize pollen (Zea mays L.) are presented for the first time. The purified protein has a molecular mass of about 35 kDa and exhibits binding affinity toward both 5S rRNA and 5S rRNA gene. It also facilitates transcription of the 5S rRNA gene in a HeLa cell extract.

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Hall, R. K., and W. L. Taylor. "Transcription factor IIIA gene expression in Xenopus oocytes utilizes a transcription factor similar to the major late transcription factor." Molecular and Cellular Biology 9, no. 11 (1989): 5003–11. http://dx.doi.org/10.1128/mcb.9.11.5003-5011.1989.

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Xenopus transcription factor IIIA (TFIIIA) gene expression is stringently regulated during development. The steady-state level of TFIIIA mRNA in a somatic cell is approximately 10(6) times less than in an immature oocyte. We have undertaken studies designed to identify differences in how the TFIIIA gene is transcribed in oocytes and somatic cells. In this regard, we have localized an upstream transcriptional control element in the TFIIIA promoter that stimulates transcription from the TFIIIA promoter approximately threefold in microinjected oocytes. The upstream element, in cis. does not stimu

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Hall, R. K., and W. L. Taylor. "Transcription factor IIIA gene expression in Xenopus oocytes utilizes a transcription factor similar to the major late transcription factor." Molecular and Cellular Biology 9, no. 11 (1989): 5003–11. http://dx.doi.org/10.1128/mcb.9.11.5003.

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Xenopus transcription factor IIIA (TFIIIA) gene expression is stringently regulated during development. The steady-state level of TFIIIA mRNA in a somatic cell is approximately 10(6) times less than in an immature oocyte. We have undertaken studies designed to identify differences in how the TFIIIA gene is transcribed in oocytes and somatic cells. In this regard, we have localized an upstream transcriptional control element in the TFIIIA promoter that stimulates transcription from the TFIIIA promoter approximately threefold in microinjected oocytes. The upstream element, in cis. does not stimu

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CHEN, Feifei, Kenji OGAWA, Raman P. NAGARAJAN, Meiyu ZHANG, Chenzhong KUANG, and Yan CHEN. "Regulation of TG-interacting factor by transforming growth factor-beta." Biochemical Journal 371, no. 2 (2003): 257–63. http://dx.doi.org/10.1042/bj20030095.

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TG-interacting factor (TGIF) is a transcriptional co-repressor that directly associates with Smad (Sma- and Mad-related protein) proteins and inhibits Smad-mediated transcriptional activation. By using Affymetrix (Santa Clara, CA, U.S.A.) oligonucleotide microarray analysis, we found that TGIF mRNA level was elevated by transforming-growth-factor-β (TGF-β) treatment in a human T-cell line, HuT78. Subsequent reverse-transcription PCR assays indicated that TGF-β1 and activin were able to induce a rapid and transient increase in the level of TGIF in both HuT78 and HepG2 hepatoma cells. To analyse

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Kołodziej, Marta, Panagiotis Tsapras, Alexander D. Cameron, and Ioannis P. Nezis. "Transcription Factor Deformed Wings Is an Atg8a-Interacting Protein That Regulates Autophagy." Cells 13, no. 22 (2024): 1897. http://dx.doi.org/10.3390/cells13221897.

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LC3 (microtubule-associated protein 1 light chain 3, called Atg8 in yeast and Drosophila) is one of the most well-studied autophagy-related proteins. LC3 controls the selectivity of autophagic degradation by interacting with LIR (LC3-interacting region) motifs also known as AIM (Atg8-interacting motifs) on selective autophagy receptors that carry cargo for degradation. Although the function of Atg8 family proteins is primarily cytoplasmic, they are also enriched in the nucleus. Despite the accumulating evidence indicating the presence of Atg8 proteins in the nucleus, the mechanisms by which th

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Kitagawa, Takao, Daiki Kobayashi, Byron Baron, et al. "AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells." PLOS ONE 17, no. 10 (2022): e0269077. http://dx.doi.org/10.1371/journal.pone.0269077.

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Ewing’s sarcoma is the second most common bone malignancy in children or young adults and is caused by an oncogenic transcription factor by a chromosomal translocation between the EWSR1 gene and the ETS transcription factor family. However, the transcriptional mechanism of EWS-ETS fusion proteins is still unclear. To identify the transcriptional complexes of EWS-ETS fusion transcription factors, we applied a proximal labeling system called BioID in Ewing’s sarcoma cells. We identified AHDC1 as a proximal protein of EWS-ETS fusion proteins. AHDC1 knockdown showed a reduced cell growth and trans

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Palvimo, J. J. "PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription." Biochemical Society Transactions 35, no. 6 (2007): 1405–8. http://dx.doi.org/10.1042/bst0351405.

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Transcriptional activity of signal-dependent transcription factors, including nuclear receptors, relies on interacting co-regulator proteins, many of which possess protein-modifying activity. SUMOs (small ubiquitin-related modifiers) and their conjugation pathway components act as co-regulator proteins for numerous transcription factors that also are often targets for SUMO modification. PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] proteins promote SUMOylation in a manner that resembles the action of RING-type ubiquitin E3 ligases. PIAS proteins

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Shimojo, Masahito, and Louis B. Hersh. "REST/NRSF-Interacting LIM Domain Protein, a Putative Nuclear Translocation Receptor." Molecular and Cellular Biology 23, no. 24 (2003): 9025–31. http://dx.doi.org/10.1128/mcb.23.24.9025-9031.2003.

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ABSTRACT The transcriptional repressor REST/NRSF (RE-1 silencing transcription factor/neuron-restrictive silencer factor) and the transcriptional regulator REST4 share an N-terminal zinc finger domain structure involved in nuclear targeting. Using this domain as bait in a yeast two-hybrid screen, a novel protein that contains three LIM domains, putative nuclear localization sequences, protein kinase A phosphorylation sites, and a CAAX prenylation motif was isolated. This protein, which is localized around the nucleus, is involved in determining the nuclear localization of REST4 and REST/NRSF.

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Dissertations / Theses on the topic "Transcription factor IIIA-interacting protein"

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Yatherajam, Gayatri. "Regulation of transcription by factors interacting with the TATA binding protein." Access citation, abstract and download form; downloadable file 7.32 Mb, 2004. http://wwwlib.umi.com/dissertations/fullcit/3131704.

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Abdallat, Ayed Mrief Ayed al. "Isolation and characterization of proteins interacting with tobacco transcription factor TGA2.2." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972633030.

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Ho, Yuen. "Proteins physically interacting with the Swi6 cell cycle regulatory transcription factor." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0002/NQ41175.pdf.

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Osman, Waffa. "Modulation of nuclear receptor function by interacting proteins /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-264-4/.

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Last, Thomas J. "Transcriptional Regulation of a Human H4 Histone Gene is Mediated by Multiple Elements Interacting with Similar Transcription Factors: A Dissertation." eScholarship@UMMS, 1998. https://escholarship.umassmed.edu/gsbs_diss/15.

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Synthesis of histone proteins occurs largely during the S phase of the cell cycle and coincides with DNA replication to provide adequate amounts of histones necessary to properly package newly replicated DNA. Controlling transcription from cell cycle dependent and proliferation specific genes, including histone H4, is an important level of regulation in the overall governance of the cell growth process. Coordination of histone gene transcription results from the cumulative effects of cell signaling pathways, dynamic chromatin structure and multiple transcription factor interactions. The resear

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Lee, Gui-in. "Structure and dynamics of the receptor kinase interacting FHA domain of kinase associated protein kinase from arabidopsis." Free to MU campus, others may purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3100058.

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Tai, Chi Shing. "Identification and characterization of Vps74p, a coatomer and SNARE interacting protein involved in membrane traffic /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202004%20TAI.

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Latreche-Carton, Céline. "Rôle oncogénique des fragments de p65/RelA Nf-kB générés par l'activité de RIPK3." Thesis, Lille 2, 2017. http://www.theses.fr/2017LIL2S048/document.

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L'utilisation d'un agent déméthylant induit la réexpression de la protéine RIP3, une sérine-thréonine kinase, dans un modèle leucémique murin exprimant BCR-ABL humain. La réexpression de RIP3 conduit rapidement les cellules vers la nécroptose. Le mutant délété du domaine kinase est de façon surprenante plus "apoptogène" et induit le clivage de p65/RelA sur le résidu d'acide aspartique D361 par la caspase 6. Pour déterminer l'impact de ce clivage, nous avons construit un mutant non clivable p65/RelA D361E, ainsi que des plasmides exprimant chacun des fragments p65/RelA 1-361 ou p65/RelA 362-549

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Nugues, Anne-Lucie. "Altération du ripoptosome dans la leucémie aiguë myéloïde." Phd thesis, Université du Droit et de la Santé - Lille II, 2013. http://tel.archives-ouvertes.fr/tel-01018661.

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Les protéines receptor-interacting protein kinase 1 (RIP1) et RIP3 ont été identifiées comme intervenant dans la régulation de la mort cellulaire apoptotique ou nécroptotique mais également dans la survie cellulaire. Ces deux protéines possèdent un domaine sérine/thréonine kinase, un domaine d'interaction spécifique RHIM (RIP homotypic interacting motif) et diffèrent dans leur domaine C-terminal car seule RIP1 possède un domaine de mort. Ces protéines font partie d'un ensemble de protéines régulatrices nommé ripoptosome. Des études ont montré une altération du ripoptosome dans les leucémies ly

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Al-Abdallat, Ayed Mrief Ayed. "Isolation and Characterization of Proteins Interacting with Tobacco Transcription Factor TGA2.2." Doctoral thesis, 2004. http://hdl.handle.net/11858/00-1735-0000-0006-ACD5-5.

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Books on the topic "Transcription factor IIIA-interacting protein"

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Ho, Yuen. Proteins physically interacting with the Swi6 cell cycle regulatory transcription factor. 1999.

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Book chapters on the topic "Transcription factor IIIA-interacting protein"

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Bhalla, Parinishtha, Anukriti Verma, Bhawna Rathi, Shivani Sharda, and Pallavi Somvanshi. "Exploring Molecular Signatures in Spondyloarthritis: A Step Towards Early Diagnosis." In Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_15.

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AbstractSpondyloarthritis is an acute inflammatory disorder of the musculoskeletal system often accompanied by pain, stiffness, bone and tissue damage. It majorly consists of ankylosing spondylitis, psoriatic arthritis and reactive arthritis. It follows a differential diagnosis pattern for demarcation between the spondyloarthritis subtypes and other arthritic subtypes such as rheumatoid arthritis, juvenile arthritis and osteoarthritis due to the heterogeneity causing gradual chronicity and complications. Presence of definite molecular markers can not only improve diagnosis efficiency but also

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2

Nunez, B. Scott, and Wayne V. Vedeckis. "Monitoring nuclear receptor function." In Receptors: Structure and function. Oxford University PressOxford, 2001. http://dx.doi.org/10.1093/oso/9780199638819.003.0011.

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Abstract The glucocorticoid receptor (GR), one of the first nuclear receptors to be characterized and to have its gene cloned, serves to illustrate the complexity of nuclear receptor function. The expression of the GR gene is regulated by at least three different promoters and the resulting mRNAs can be differentially spliced into several transcriptional variants (1-3). Following the translation of these transcripts into protein, the activity and/or subcellular distribution of the GR protein may be modified by post-translational modifications such as phosphorylation (4). In the absence of liga

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Pieler, Tomas. "Interaction of 5S RNA -with TFIIIA." In RNA-Protein Interactions. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780199635054.003.0008.

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Abstract Among the structural motifs which identify DNA- and RNA-binding proteins in eukaryotes, zinc finger modules are unique in defining the nucleic acid-binding domain in proteins with a demonstrated ability to form sequence-specific com plexes with either RNA or DNA or even with both classes of nucleic acids (1). Transcription factor IIIA (TFIIIA) is the founding member of the zinc finger protein superfamily, which is comprised of several hundred members in vertebrates (2, 3). TFIIIA is one of the most abundant proteins in immature Xenopus laevis oocytes, where it is found primarily in a

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Sierra, Felipe, Jian-Min Tian, and Ueli Schibler. "In vitro transcription with nuclear extracts from differentiated tissues." In Gene Transcription. Oxford University PressOxford, 1993. http://dx.doi.org/10.1093/oso/9780199632923.003.0004.

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Abstract Much recent research in molecular biology is focusing on the molecular interactions that control transcription. Transcription of protein-coding genes is performed by RNA polymerase II (pol II). This enzyme, however, is not capable of recognizing bona fide promoters by itself. To do so, it requires protein-protein interactions with a number of ancillary factors (1). Some of these transcription factors, the so-called basal factors, are needed for the initiation of transcription at most promoters (2). In contrast, some promoter¬ specific regulatory proteins stimulate transcription of onl

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Galat, Andrzej, and Sylvie Riviere. "Proteins interacting with PPlases." In Peptidyl–Prolyl Cis/Trans lsomerases. Oxford University PressOxford, 1998. http://dx.doi.org/10.1093/oso/9780198502883.003.0004.

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Abstract Specific interactions between PPiases (immunophilins) and various intracellular proteins are summarized in this chapter. PPiases are important factors for in vivo protein folding and assembly of infectious particles of HIV-2 and HIV-1, and they may be involved in the transcription of the HIV genome [400]. Some PPiases function as ‘foldases’ and are associated with other protein components of the cellular machinery for translocating proteins from the cytosol to the lumen of the ER, folding of proteins in the mitochondria and secretion of gene products to the extracellular space [384, 4

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Hampsey, Michael. "RNA polymerase II transcriptional machinery." In The Yeast Nucleus. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199637737.003.0006.

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Abstract Transcription initiation by RNA polymerase II (RNAP II) requires interaction between cis-acting promoter elements and trans-acting factors. The eukaryotic promoter consists of core elements that include the TATA box and other DNA sequences that define transcription start sites, and regulatory elements that either enhance or repress transcription in a gene-specific manner. The core promoter is the site of assembly of the transcription preinitiation complex (PIC), which includes RNAP II and the general transcription factors (GTFs) TATA-binding protein (TBP), TFIIB, TFIIE, TFIIF, and TFI

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Lucchesi, John C. "The role of non-coding RNAs." In Epigenetics, Nuclear Organization & Gene Function. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198831204.003.0006.

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Most of the genome is transcribed into non-coding transcripts that far exceed in number the transcripts of protein-coding genes. These RNAs are subdivided into different classes. Long non-coding RNAs (lncRNAs) are at least 200 nucleotides in length and are transcribed from promoter, coding, intergenic or enhancer regions (eRNAs). These RNAs repress or enhance the transcription of target genes by facilitating the interaction between promoters and enhancers or by interacting with transcription factors and targeting histone-modifying enzymes. Short non-coding RNAs include a diverse group of funct

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Pfahl, Magnus, Xiao-Kun Zhang, Jürgen M. Lehmann, Matthias Husmann, Gerhart Graupner, and Birgit Hoffmann. "Molecular mechanisms of retinoic acid action." In Retinoids in Normal Development and Teratogenesis. Oxford University PressOxford, 1992. http://dx.doi.org/10.1093/oso/9780198547709.003.0004.

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Abstract The multitude of essential biological processes regulated by the vitamin A derivative retinoic acid (RA) and synthetic analogues (retinoids) (reviewed in Lotan 1980; Sporn et al. 1984), combined with the many beneficial and undesirable side-effects (Lippman et al. 1987) associated with retinoid therapies, suggest the existence of a highly complex regulatory mechanism. How can a single substance —RA—regulate a large diversity of programmes and, in addition, provoke at times opposite effects, e.g. during limb morphogenesis, where low concentrations of RA can lead to duplications of digi

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Jabs, Ethylin Wang. "TWIST1 and the Saethre–Chotzen Syndrome." In Inborn Errors Of Development. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195306910.003.0046.

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Abstract Saethre–Chotzen syndrome (OMIM 101400) is one of the most common craniosynostosis syndromes with autosomal dominant inheritance. The most frequently observed features are the premature fusion of coronal sutures resulting in brachycephaly, low frontal hairline, facial asymmetry, ptosis of the eyelids, prominent helical crus, syndactyly, and broad great toes. This syndrome is caused by mutations in the TWIST1 gene that map to chromosome 7p21 and codes for a basic helix–loop–helix (bHLH) transcription factor (OMIM 601622). At least 97 different mutations, including missense and nonsense

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Bessa-Pereira, Catarina, Ricardo Dias, Elsa Brandão, et al. "Eat Tasty and Healthy: Role of Polyphenols in Functional Foods." In Functional Foods [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96577.

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Adverse reactions to food such as allergies and celiac disease are increasingly recognized as a growing public health burden. There is currently no cure for these diseases so that there is an unmet need to evaluate different nutritional approaches aiming at improving the quality of life of affected patients and their families. In this context, healthy promising nature-derived compounds, most of which contained in fruits and vegetables, have been studied as an alternative to attenuate the epidemic. Indeed, phenolic compounds have become an emerging field of interest in nutrition in the last dec

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Conference papers on the topic "Transcription factor IIIA-interacting protein"

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"Expression of IPD3, a transcriptional regulator of AM symbiosis, affects immunity and flowering time in non-host Arabidopsis." In IS-MPMI Congress. IS-MPMI, 2023. http://dx.doi.org/10.1094/ismpmi-2023-13.

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Arbuscular mycorrhizal symbiosis (AM) is a beneficial trait originating with the first land plants. The ability to host AM has since been lost from diverse plant species. Genes in the Common Symbiosis Pathway that are essential to establish AM hosting were lost from Brassicaceae along with the trait itself, including Interacting Protein of DMI3 (IPD3), a key transcription factor connecting upstream signaling of AM fungal presence to the downstream gene-regulatory network for AM functions. We generated transgenic Arabidopsis plants expressing the DNA-binding domain of IPD3 and used phenotypic a

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Souza, Priscila M., Filomena M. Carvalho, Fernando N. Aguiar, Débora Gagliato, and Alfredo C. S. D. Barros. "ASSOCIATION BETWEEN GATA3 AND PATHOLOGIAL AND IMMUNOHISTOCHEMICAL PREDICTIVE AND PROGNOSTIC PARAMETERS IN EARLY BREAST CANCER." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1046.

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Introduction: GATA3 gene, at 10p14, a member of the GATA family with two GATA-type zinc-fingers, encodes the transcription factors GATA - binding protein 3 (GATA3), critical for the luminal breast epithelium development and maintenance. The GATA3 protein is a linear one, with more than 400 aminoacids, that can be recognized by immunohistochemical analysis. Mutations of the GATA3 and loss of the expression of its related protein are implicated in breast cancer development and aggressiveness. As the most frequent transcription factor in luminal tumor cells, GATA3 became an important marker of ma

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Marquerie, G., A. Duperray, G. Uzan, and R. Berthier. "BIOSYNTHETIC PATHWAYS OF THE PLATELET FIBRINOGEN RECEPTOR IN HUMAN MEGAKARYOCYTES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642954.

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Interaction between cells and between cells and extracellular matrices are critical for a number of biological processes, including organ development, cell differenciation, cell motility, and the inimune' response. These interactions are mediated by a family of adhesion receptors that recognize short sequences such as Arg-Gly-Asp (RGD). These receptors share similar structural properties. They are heterodimers composed of a and B subunits and sometime express common epitopes. This suggests that the structural and functional relationship of these receptors may result from the transcription of r

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Hensel, Tim, Chiara Giorgi, Fiona Becker-Dettling, et al. "Abstract A27: BET bromodomain proteins in Ewing sarcoma regulate a specific transcriptional program, tumorigenicity and apoptosis by interacting with EWS-FLI1 and the positive transcription elongation factor." In Abstracts: AACR International Conference: New Frontiers in Cancer Research; January 18-22, 2017; Cape Town, South Africa. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.newfront17-a27.

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Reports on the topic "Transcription factor IIIA-interacting protein"

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Barg, Rivka, Erich Grotewold, and Yechiam Salts. Regulation of Tomato Fruit Development by Interacting MYB Proteins. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7592647.bard.

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Background to the topic: Early tomato fruit development is executed via extensive cell divisions followed by cell expansion concomitantly with endoreduplication. The signals involved in activating the different modes of growth during fruit development are still inadequately understood. Addressing this developmental process, we identified SlFSM1 as a gene expressed specifically during the cell-division dependent stages of fruit development. SlFSM1 is the founder of a class of small plant specific proteins containing a divergent SANT/MYB domain (Barg et al 2005). Before initiating this project,

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Chen, Junping, Zach Adam, and Arie Admon. The Role of FtsH11 Protease in Chloroplast Biogenesis and Maintenance at Elevated Temperatures in Model and Crop Plants. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699845.bard.

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specific objectives of this proposal were to: 1) determine the location, topology, and oligomerization of FtsH11 protease; 2) identify the substrate/s of FtsH11 and the downstream components involved in maintaining thermostability of chloroplasts; 3) identify new elements involved in FtsH11 protease regulatory network related to HT adaptation processes in chloroplast; 4) Study the role of FtsH11 homologs from crop species in HT tolerance. Background to the topic: HT-tolerant varieties that maintain high photosynthetic efficiency at HT, and cope better with daily and seasonal temperature fluctu

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Olszewski, Neil, and David Weiss. Role of Serine/Threonine O-GlcNAc Modifications in Signaling Networks. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7696544.bard.

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Significant evidence suggests that serine/threonine-O-linked N-acetyl glucosamine0-(GlcNAc) modifications play a central role in the regulation of plant signaling networks. Forexample, mutations in SPINDLY,) SPY (an O-GlcNAc transferase,) OGT (promote gibberellin GA) (signal transduction and inhibit cytokinin responses. In addition, mutating both Arabidopsis OGTsSEC (and SPY) causes embryo lethality. The long-term goal of this research is to elucidate the mechanism by which Arabidopsis OGTs regulate signaling networks. This project investigated the mechanisms of O-GlcNAc regulation of cytokini

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