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1

Sheagley, Eric Eugene. "Mechanisms of transcription elongation and the nuclease activity of RNA polymerase II /." view abstract or download file of text, 2003. http://wwwlib.umi.com/cr/uoregon/fullcit?p3080598.

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Thesis (Ph. D.)--University of Oregon, 2003.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 119-129). Also available for download via the World Wide Web; free to University of Oregon users.
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2

Chisholm, Robert David. "Mutations in RNA polymerase II that affect poly (a)-dependent termination /." view abstract or download file of text, 2006. http://proquest.umi.com/pqdweb?did=1188876151&sid=1&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2006.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 80-86). Also available for download via the World Wide Web; free to University of Oregon users.
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3

Micorescu, Michael. "The Function of an Alternate TFB from Pyrococus furiosus and the Orientation of the TFB B-reader within Archaeal Transcription Initiation Complexes." PDXScholar, 2010. https://pdxscholar.library.pdx.edu/open_access_etds/278.

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The genome of the hyperthermophile archaeon Pyrococcus furiosus encodes two transcription factor B (TFB) paralogs, one of which (TFB1) was previously characterized in transcription initiation. The second TFB (TFB2) is unusual in that it lacks recognizable homology to the archaeal TFB/eukaryotic TFIIB B-reader (also called the B-finger) motif. TFB2 functions, though poorly, in promoter-dependent transcription initiation. Domain swaps between TFB1 and TFB2 showed that the low activity of TFB2 is determined mainly by its N terminus. The low activity of TFB2 in promoter opening and transcription c
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4

Ranish, Jeffrey A. "Mechanisms of transcription by RNA Polymerase II /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/5057.

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5

Reichow, Steve L. "Structure and function of RNA modification and transcription regulation factors by NMR /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/11596.

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6

Ouyang, Ching. "Investigation of the role of TBP-TATA interaction in differential transcription of two alanine tRNA genes in silkworm Bombyx mori /." view abstract or download file of text, 1999. http://wwwlib.umi.com/cr/uoregon/fullcit?p9947978.

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Thesis (Ph. D.)--University of Oregon, 1999.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 90-101). Also available for download via the World Wide Web; free to University of Oregon users. Address: http://wwwlib.umi.com/cr/uoregon/fullcit?p9947978.
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7

Chang, Ya-Wen. "The Ras/PKA pathway controls transcription of genes involved in stationary phase entry in Saccharomyces cerevisiae." Columbus, Ohio : Ohio State University, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1061214472.

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Thesis (Ph. D.)--Ohio State University, 2003.<br>Title from first page of PDF file. Document formatted into pages; contains xiii, 108 p.; also includes graphics. Includes abstract and vita. Advisor: Paul K. Herman, Dept.of Molecular, Cellular, and Developmental Biology. Includes bibliographical references (p. 96-108).
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8

Yang, Margaret Hwae-Ling. "Mutations flanking the DNA channel through RNA polymerase II affect transcription-coupled repair in Saccharomyces cerevisiae /." view abstract or download file of text, 2007. http://proquest.umi.com/pqdweb?did=1417800941&sid=1&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2007.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 80-87). Also available for download via the World Wide Web; free to University of Oregon users.
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9

Lee, Sally. "Architecture of RNA polymerase II and RNA polymerase III pre-initiation transcription complexes /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/9213.

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10

Martinez, Maria Juanita. "Transcription factor IIIB binding to two classes of Alanine tRNA gene promoters of the silkmoth, Bombyx mori /." view abstract or download file of text, 2001. http://wwwlib.umi.com/cr/uoregon/fullcit?p3018382.

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Thesis (Ph. D.)--University of Oregon, 2001.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 128-143). Also available for download via the World Wide Web; free to University of Oregon users.
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11

O'Gorman, William Evert. "Analysis of cyclin H interaction with non-coding RNAs." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670092.

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12

Colbert, Trenton. "Characterization of BRF1, an RNA polymerase III transcription factor /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/6320.

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13

Awrey, Donald E. "Structural and functional analysis of the yeast general transcript elongation factor, TFIIS." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0009/NQ30069.pdf.

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14

Kotova, Irina. "Purification of general RNA polymerase II transcription factors from mouse for studies of proliferation-specific transcription." Doctoral thesis, Umeå : Department of Medical BIochemistry and Biophysics, Umeå University, 2003. http://publications.uu.se/umu/theses/abstract.xsql?dbid=91.

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15

Reeves, Wendy Michele. "Diverse functions of yeast co-activators in RNA polymerase II transcription /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/5058.

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16

Yudkovsky, Natalya. "Mechanisms of factor recruitment at promoters during RNA polymerase II transcription /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/5046.

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17

Tronnersjö, Susanna. "Functional studies of RNA polymerase II-dependent transcription in yeast Saccharomyces cerevisiae /." Uppsala : Department of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/2006109.pdf.

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18

Hilton, Traci Leigh. "Dual function of TAF1 in basal and activated cyclin D1 transcription /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/6275.

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19

Pearson, Erika L. Erie Dorothy A. "Regulation of transcription elongation via interactions of RNA polymerase with sequence elements and accessory factors." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,2116.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2008.<br>Title from electronic title page (viewed Feb. 17, 2009). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry." Discipline: Chemistry; Department/School: Chemistry.
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20

Luo, Weifei. "The coupling of transcription termination by RNA polymerase II to MRNA 3' end processing in Saccharomyces cerevisiae /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2006.

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Thesis (Ph.D. in Biochemistry) -- University of Colorado at Denver and Health Sciences Center, 2006.<br>Typescript. Includes bibliographical references (leaves 135-145). Free to UCD Anschutz Medical Campus. Online version available via ProQuest Digital Dissertations;
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21

Caglio, Giulia. "RNA Polymerase II identifies enhancers in different states of activation." Doctoral thesis, Humboldt-Universität zu Berlin, 2019. http://dx.doi.org/10.18452/19946.

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Enhancer regulieren die Transkription ihrer Zielgene und deren Expression. Sie bieten eine Bindestelle für verschiedenste Transkriptionsfaktoren (TF) und RNA Polymerase II (RNAPII) und unterstützen die Gentranskription durch das Zustandekommen von Chromatinkontakten. Zusätzlich transkribiert RNAPII in Enhancer-Regionen kurze, non-polyadenylierte Transkripte, die man Enhancer-RNA (eRNA) nennt. Der Mechanismus der RNAPII-Rekrutierung und –Regulation an Enhancern ist bisher wenig verstanden, insbesondere wie das Vorhandensein von RNAPII-Modifikationen den Chromatinstatus, -faltung sowie die Genak
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22

Fenouil, Romain. "Etude des mécanismes de la régulation transcriptionnelle et développement d'outils bioinformatiques pour le traitement des données de séquençage haut débit." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM4089.

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Les mécanismes de régulation de l’expression génétique sont essentiels pour l’adaptation du comportement cellulaire face à son environnement (différenciation, développement, réponse à un stimulus). Les études moléculaires décrivent une grande diversité de facteurs impliqués dans ce phénomène (TFs, marques épigénétiques, nucléosomes) et plusieurs niveaux de régulation (initiation, élongation, épissage, maturation) qui expliquent la complexité du transcriptome cellulaire. Durant ma thèse, nous nous sommes intéressés aux processus de régulation de la transcription en nous appuyant sur le modèle d
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23

Ferreiro, Neira Isabel. "Transcriptional regulation by the mammalian stress-activated protein kinase p38." Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/80661.

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Regulation of transcription by Stress Activated Protein Kinases (SAPKs) is an essential aspect for adaptation to extracellular stimuli. In mammals, the activation of the p38 SAPK results in the regulation of gene expression through the direct phosphorylation of several transcription factors. However, how p38 SAPK regulates the proper gene expression program of adaptation to stress as well as the basic mechanisms used by the SAPK remains uncharacterized. The results displayed in this manuscript show that the p38 SAPK plays a central role in the regulation of gene expression upon stress, as up t
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24

O'Brien, Siobhan. "Regulation of Cellular and HIV-1 Gene Expression by Positive Transcription Elongation Factor B: A Dissertation." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/528.

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RNA polymerase II-mediated transcription of HIV-1 genes depends on positive transcription elongation factor b (P-TEFb), the complex of cyclin T1 and CDK9. Recent evidence suggests that regulation of transcription by P-TEFb involves chromatin binding and modifying factors. To determine how P-TEFb may connect chromatin remodeling to transcription, we investigated the relationship between P-TEFb and histone H1. We show that P-TEFb interacts with H1 and that H1 phosphorylation in cell culture correlates with P-TEFb activity. Importantly, P-TEFb also directs H1 phosphorylation during Tat transacti
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25

Shah, Sheila Marie Alojipan. "Studies on RNA polymerase III transcription : Structural organization of transcription factor IIIb /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2001. http://wwwlib.umi.com/cr/ucsd/fullcit?p3025949.

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26

Niedbala, Angela Rochelle. "Kinetic studies of transcription initiation by wild type T7 RNA polymerase, his-tagged wild type T7 RNA polymerase and GP1-Lys222 T7 RNA polymerase." Thesis, Georgia Institute of Technology, 1995. http://hdl.handle.net/1853/27288.

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27

Nayak, Dhananjaya. "Conformational mechanisms in T7 RNA polymerase transcription a dissertation /." San Antonio : UTHSC, 2008. http://learningobjects.library.uthscsa.edu/cdm4/item_viewer.php?CISOROOT=/theses&CISOPTR=44&CISOBOX=1&REC=11.

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28

Åberg, Anna. "New insights into the role of ppGpp and DksA through their effect on transcriptional regulation of housekeeping and colonization related genes of Escherichia coli." Doctoral thesis, Umeå universitet, Molekylärbiologi (Medicinska fakulteten), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1669.

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Bacteria have the ability to sense different environmental signals. When an environmental stress is detected, bacteria rapidly adjust their gene expression profile to be able to survive and thrive. The transduction of such environmental signals often requires the coordinated involvement of several factors that constitute complex regulatory networks. Hence, depending on the combination of signals, a unique gene expression profile required to adapt to the specific stress conditions is generated. Proteins are the best-known regulatory factors. However, non-proteinaceous molecules are also importa
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29

Bailey, Paul Austyn. "Inhibition of T7 RNA polymerase by T7 lysozyme." Diss., Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/30418.

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30

Henfrey, R. D. "In vitro transcription of exogenous plant DNA." Thesis, University of Hertfordshire, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381604.

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31

Moreland, Rodney J. "Molecular interactions in RNA polymerase II and III transcription systems /." Full-text version available from OU Domain via ProQuest Digital Dissertations, 1998.

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32

Guo, Xieyang. "Regulation of transcription : structural studies of an RNA polymerase elongation complex bound to transcription factor NusA." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAJ071/document.

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La pause transcriptionnelle marquée par les ARN polymérases (RNAP) est un mécanisme clé pour réguler l'expression des gènes dans tous les règnes de la vie et est une condition préalable à la terminaison de la transcription. Le facteur de transcription bactérien essentiel NusA stimule à la fois la pause et la terminaison de la transcription, jouant ainsi un rôle central. Ici, je présente des reconstructions par cryo-microscopie électronique (cryo-EM) à une seule particule de NusA lié à des complexes d'élongation en présence et en absence d’ARN en épingle à cheveux dans le canal de sortie de l'A
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33

Glover-Cutter, Kira Marina. "Integration of POL II transcription with pre-MRNA processing on human genes /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2008.

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Thesis (Ph.D. in Molecular Biology) -- University of Colorado Denver, 2008.<br>Typescript. Includes bibliographical references (leaves 185-214). Free to UCD Anschutz Medical Campus. Online version available via ProQuest Digital Dissertations;
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34

Xie, Yunwei. "Nucleosomes, transcription and transcription regulation in Archaea." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1127830717.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xiv, 200 p.; also includes graphics (some col.). Includes bibliographical references (p. 167-197). Available online via OhioLINK's ETD Center
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35

Kantidakis, Theodoros. "In vivo studies of repressors of RNA polymerase III transcription." Thesis, Thesis restricted. Connect to e-thesis to view abstract, 2008. http://theses.gla.ac.uk/161/.

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Thesis (Ph.D.) - University of Glasgow, 2008.<br>Ph.D. thesis submitted to the Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, 2008. Includes bibliographical references. Print version also available.
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36

Xiong, Yalin. "Downstream NTP effects on human RNA polymerase II transcription elongation." Diss., Connect to online resource - MSU authorized users, 2008.

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Thesis (Ph.D.)--Michigan State University. Dept. of Biochemistry and Molecular Biology, 2008.<br>Title from PDF t.p. (viewed on Apr. 2, 2009) Includes bibliographical references. Also issued in print.
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37

Apone, Lynne Marie. "Analysis of TAF II Function in the Yeast Saccharomyces Cerevisiae." eScholarship@UMMS, 1998. https://escholarship.umassmed.edu/gsbs_diss/183.

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Transcription by RNA polymerase II is a highly regulated process requiring a number of general and promoter specific transcription factors. Although many of the factors involved in the transcription reaction are known, exactly how they function to stimulate or repress transcription is not well understood. Central to understanding gene regulation is understanding the mechanism by which promoter specific transcription activators (activators) stimulate transcription. A group of factors called coactivators have been shown to be required for activator function in vitro. The best characterized coact
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38

Warshamana, Gnana Sakuntala. "Interactions of T7 RNA polymerase with its promoters : Part I: T7 promoter contacts essential for promoter activity in vivo ; Part II: Isolation and characterization of a mutant T7 RNA polymerase with altered promoter specificity." Diss., Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/26303.

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39

Hemming, Sally Anne. "Functional analysis of the ninth subunit of yeast RNA polymerase II, RPB9 / by Sally Anne Hemming." *McMaster only, 1998.

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40

Nesser, Nicole Katherine. "RNA polymerase II subunit RPB9 is important for transcriptional fidelity and processivity /." view abstract or download file of text, 2005. http://wwwlib.umi.com/cr/uoregon/fullcit?p3201694.

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Thesis (Ph. D.)--University of Oregon, 2005.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 78 - 83). Also available for download via the World Wide Web; free to University of Oregon users.
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41

Zechner, Kerstin. "3' end processing and RNA polymerase II transcription termination in protein coding genes in the nematode C. elegans." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564397.

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In all organisms studied so far, the recognition of a functional poly(A) site is essential for RNA polymerase II termination at the end of nearly all genes transcribed by this enzyme (Whitelaw and Proudfoot, 1986; Guo et al., 1995; Birse et al. 1997). A number of eukaryotes have some of their genes organised in polycistronic structures which resemble bacterial operons (Davis and Hodgson, 1997; Ganot et al., 2004; Spieth et al. 1993), and in C. elegans, approximately 20% of all genes are contained within these operon-like structures (Blumenthal et al., 2002). Here, functional poly(A) sites will
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42

Jiang, Yunnan. "Testing the occurrence of forward hyper-translocation during the promoter escape transition / Yunnan Jiang." Connect to online version, 2009. http://ada.mtholyoke.edu/setr/websrc/pdfs/www/2009/381.pdf.

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43

Banks, Charles Antony Scott. "Regulation of RNA polymerase II transcription elongation in Schizosaccharomyces pombe by SpELL and associated factor SpEAF." Thesis, Open University, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520739.

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44

Selvakumar, Tharakeswari. "Regulation of the human U6 small nuclear RNA transcription by the Retinoblastoma tumor suppressor protein." Diss., Connect to online resource - MSU authorized users, 2008.

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45

Schreieck, Amelie. "Role of the RNA polymerase II C-terminal domain in transcription termination and function of Spt5 in 3' RNA-processing factor recruitment." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-164544.

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Protein-coding genes in eukaryotes are transcribed by RNA polymerase II (Pol II). This process is tightly regulated and coupled to RNA processing. Many transcription and RNA processing factors are recruited to Pol II via its conserved C-terminal domain (CTD) containing 27 heptapeptide repeats of the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 in Saccharomyces cerevisiae. These repeats can be differentially phosphorylated during the transcription cycle serving as a code for interacting factors. During transcription initiation, Ser5 is phosphorylated at the 5’-end of genes and this pho
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46

Larkin, Robert M. "Analysis of nuclear DNA-dependent RNA polymerase subunits and tata-binding protein from plants /." free to MU campus, to others for purchase, 1996. http://wwwlib.umi.com/cr/mo/fullcit?p9821341.

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47

Lescure, Alain. "Etude des mecanismes de la transcription des genes de sn rna u1 et u6 par les rna polymerases deux et trois." Université Louis Pasteur (Strasbourg) (1971-2008), 1993. http://www.theses.fr/1993STR13159.

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Les travaux presentes dans ce memoire concernent l'etude fonctionnelle des elements promoteurs et activateurs de la transcription des genes de snrna et la determination de leur role dans la specificite de la transcription par les rna polymerases 2 ou 3. Nous avons montre que l'element promoteur pse du gene u1 definit une sorte de fenetre a l'interieur de laquelle un motif ca est choisi comme site unique d'initiation de la transcription. En ce qui concerne la transcription du gene u6 par la rna polymerase 3, des etudes anterieures avaient montre que la sequence tata est un determinant majeur de
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48

Oficjalska, Danuta. "Etude du mode d'action de la protéine Maf1 lors de la répression de la transcription par l'ARN polymérase III chez Saccharomyces cerevisiae." Paris 7, 2006. http://www.theses.fr/2006PA077145.

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L'ARN polymérase III (Pol III), avec P aide de facteurs multiprotéiques, synthétise les ARN de transfert, l'ARN ribosomique 55 et d' autres ARN stables et non traduits. La transcription de ces gènes par la Pol III joue un rôle essentiel dans le contrôle de la synthèse protéique et des croissance et prolifération cellulaires. La Pol III interagit physiquement avec Maf1, une protéine conservée chez les eucaryotes supérieurs. Maf1 réprime P expression des gènes transcrits parla Pol III. Nous avons montré par immunoprécipitation de chromatine analysée sur puce à ADN qu' en réponse à un stress cell
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49

Chakraborty, Atanu. "Mechanism Of mom Gene Transactivation By Transcription Factor C Of Phage MU." Thesis, Indian Institute of Science, 2006. http://hdl.handle.net/2005/275.

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Regulation of transcription initiation is the major determining event employed by the cell to control gene expression and subsequent cellular processes. The weak promoters, with low basal transcription activities, are activated by activators. Bacteriophage Mu mom gene, which encodes a unique DNA modification function, is detrimental to cell when expressed early or in large quantities. Mu has designed a complex, well-controlled and orchestrated regulatory network for mom expression to ensure its synthesis only in late lytic cycle. The phage encoded transcription activator protein C activates th
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50

Ayoub, Nayla. "Conséquences physiologiques et mécanistiques de l'intéraction covalente du facteur Rrn3 avec l'ARN polymérase I chez la levure Saccharomyces cerevisiae." Paris 7, 2009. https://tel.archives-ouvertes.fr/tel-00446803.

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Chez les Eucaryotes, la transcription du génome nucléaire est assurée par trois formes d'ARN polymérase ADN dépendantes (Pol I, II et III) qui transcrivent chacune une classe spécifique de gènes. Ainsi, la Pol I transcrit uniquement le gène codant le précurseur des grands ARN ribosomiques. La transcription Pol I est extrêmement active et représente plus de 60% de l'activité transcriptionnelle totale de la cellule en phase exponentielle de croissance. Nous avons étudié chez la levure S. Cerevisiae les effets de traitements longs à la rapamycine sur la transcription Pol I. Grâce à une souche mut
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