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Dissertations / Theses on the topic 'Transcription initiation sites'

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1

Auchincloss, Andrea Helen. "Transcription initiation sites on the soybean mitochondrial genome." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=63914.

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2

Voronin, Yegor A. "Investigation of initiation of reverse transcription in retroviruses using vectors with two primer-binding sites." Morgantown, W. Va. : [West Virginia University Libraries], 2003. http://etd.wvu.edu/templates/showETD.cfm?recnum=3136.

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3

Yamaguchi, Shun. "Regional Expression and Regulation of Alternative Forms of mRNAs Derived from Two Distinct Transcription Initiation Sites of the Rat mGluR5 Gene." Kyoto University, 1998. http://hdl.handle.net/2433/182240.

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4

Sidarovich, Viktoryia. "Transcription of the human plasma prekallikrein gene : demonstration of alternative promoters, multiple initiation sites, and alternative splicing and identification of cis-acting DNA elements." kostenfrei, 2008. http://mediatum2.ub.tum.de/doc/645828/645828.pdf.

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5

Zhang, Yuanyuan. "TRANSLATIONAL REGULATORY MECHANISMS OF THE RAT AND HUMAN MULTIDRUG RESISTANCE PROTEIN 2." UKnowledge, 2008. http://uknowledge.uky.edu/gradschool_diss/649.

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Multidrug resistance protein 2 (MRP2) is the second member the C subfamily in the superfamily of adenosine triphosphate (ATP)-binding cassette (ABC) efflux transporters. MRP2 is a critical player for generation of bile acidindependent bile flow and biliary excretion of glutathione, glucuronate and sulfate conjugates of endo- and xenobiotics. Dysfunctional expression of MRP2 is associated with Dubin-Johnson Syndrome. Pathological and physiological states or xenobiotics change the MRP2 expression level. Under some conditions, expression of the human MRP2 and rat Mrp2 proteins are regulated at th
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6

Raborn, R. Taylor. "Genome-wide analysis of transcription initiation and promoter architecture in eukaryotes." Diss., University of Iowa, 2012. https://ir.uiowa.edu/etd/4728.

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The transcriptome represents the entirety of RNA molecules within a cell or tissue at a given time. Recent advances have facilitated the production of large-scale, global interrogations of transcriptomes, finding that genomes are extensively transcribed and contain diverse classes of RNAs (Dinger et al., 2009). Information generated by high-throughput analyses of mRNA transcription start sites (TSSs) such as CAGE (Cap Analysis of Gene Expression) indicate that eukaryotic genomes have complex landscapes of transcription initiation. The TSS is important for the annotation of cis-regulatory seque
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7

Bharadwaj, Rahul. "Regulation of Higher Order Chromatin at GRIN2B and GAD1 Genetic Loci in Human and Mouse Brain: A Dissertation." eScholarship@UMMS, 2013. https://escholarship.umassmed.edu/gsbs_diss/651.

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Little is known about higher order chromatin structures in the human brain and their function in transcription regulation. We employed chromosome conformation capture (3C) to analyze chromatin architecture within 700 Kb surrounding the transcription start site (TSS) of the NMDA receptor and schizophrenia susceptibility gene, GRIN2B, in human and mouse cerebral cortex. Remarkably, both species showed a higher interaction between the TSS and an intronic sequence, enriched for (KRAB) Krueppel associated Box domain binding sites and selectively targeted by the (H3K9) histone 3 lysine 9 specific me
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Bharadwaj, Rahul. "Regulation of Higher Order Chromatin at GRIN2B and GAD1 Genetic Loci in Human and Mouse Brain: A Dissertation." eScholarship@UMMS, 2002. http://escholarship.umassmed.edu/gsbs_diss/651.

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Little is known about higher order chromatin structures in the human brain and their function in transcription regulation. We employed chromosome conformation capture (3C) to analyze chromatin architecture within 700 Kb surrounding the transcription start site (TSS) of the NMDA receptor and schizophrenia susceptibility gene, GRIN2B, in human and mouse cerebral cortex. Remarkably, both species showed a higher interaction between the TSS and an intronic sequence, enriched for (KRAB) Krueppel associated Box domain binding sites and selectively targeted by the (H3K9) histone 3 lysine 9 specific me
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9

Palii, Stela S. "Transcriptional regulation of the human system a amino acid transporter, snat2 gene by amino acid availability." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0008371.

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Thesis (Ph.D.)--University of Florida, 2004.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 210 pages. Includes Vita. Includes bibliographical references.
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10

Pauly, Marc. "Etude structurale et fonctionnelle de la sequence tata du promoteur precoce du virus simien sv40." Université Louis Pasteur (Strasbourg) (1971-2008), 1989. http://www.theses.fr/1989STR13043.

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Dans le but d'elucider les mecanismes moleculaires de la regulation de l'expression des genes, une etude structurale et fonctionnelle detaillee de la sequence tata du promoteur precoce du virus sv40 est realisee. La mutagenese dirigee utilisant des oligodesoxynucleotides de synthese permet la localisation des domaines fonctionnels de deux elements tata situes dans la region d'origine de replication virale. Chacun des elements dirige independamment l'initiation precise et efficace de la transcription precoce in vivo a partir d'un groupe de sites definis
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11

Myers, Stephen Anthony. "Kallikrein Gene Regulation in Hormone-Dependent Cancer Cell Lines." Queensland University of Technology, 2003. http://eprints.qut.edu.au/15842/.

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Hormone-dependent cancers (HDCs), such as those of the prostate, ovary, breast and endometrium, share characteristics that indicate similar underlying mechanisms of carcinogenesis. Through steroid hormone signalling on "down-stream" target genes, the growth, development and progression of HDCs are regulated. One such family of target genes, highly expressed in HDCs and regulated by steroid hormones, are the tissue kallikreins (KLKs). The KLKs are a multigene family of serine proteases involved in physiological processes such as blood pressure regulation, inflammation, and tumour development an
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12

Ya-Ling, Chen, and 程雅玲. "Characterization of the Transcription and Translation Initiation Sites of Epstein-Barr Virus BGLF4 Protein Kinase and It's Possible Ganciclovir Kinase Activity." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/23797226603881205002.

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碩士<br>國立臺灣大學<br>微生物學研究所<br>89<br>The Epstein-Barr virus (EBV) open reading frame BGLF4 was identified as a ser/thr protein kinase based on the homology alignment to the conserved motifs of known protein kinases. In a previous study, by using an EBNA-1 tag, the immunoprecipitated BGLF4 was demonstrated for its abilities of autophosphorylation and phosphorylating casein, histone, and EBV early-antigen diffuse type (EA-D). According to the EBV genome map, BGLF4 is located at nt 123,692-122,328 of B95-8 EBV. Since no in frame ATG was identified at 123,692, the first in frame ATG at 123,614 was use
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13

Gressel, Saskia. "Multi-omics analysis of transcription kinetics in human cells." Doctoral thesis, 2019. http://hdl.handle.net/21.11130/00-1735-0000-0003-C183-E.

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14

Sidarovich, Viktoryia [Verfasser]. "Transcription of the human plasma prekallikrein gene : demonstration of alternative promoters, multiple initiation sites, and alternative splicing and identification of cis-acting DNA elements / Viktoryia Sidarovich." 2008. http://d-nb.info/989357244/34.

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15

Majovski, Robert C. "Structure-function analysis of the Saccharomyces cerevisiae RNA polymerase II active center a functional role for the switch 2 region in transcription start site utilization and abortive initiation /." 2007. http://proquest.umi.com/pqdweb?did=1402170981&sid=15&Fmt=2&clientId=39334&RQT=309&VName=PQD.

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Thesis (Ph.D.)--State University of New York at Buffalo, 2007.<br>Title from PDF title page (viewed on Mar. 06, 2008) Available through UMI ProQuest Digital Dissertations. Thesis adviser: Ponticelli, Alfred S. Includes bibliographical references.
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