Relevant bibliographies by topics / Transcriptional activator-like effector

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  2. Dissertations / Theses
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  4. Conference papers

Academic literature on the topic 'Transcriptional activator-like effector'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "Transcriptional activator-like effector"

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Kim, Jung-Gun, and Mary Beth Mudgett. "Tomato bHLH132 Transcription Factor Controls Growth and Defense and Is Activated by Xanthomonas euvesicatoria Effector XopD During Pathogenesis." Molecular Plant-Microbe Interactions® 32, no. 12 (2019): 1614–22. http://dx.doi.org/10.1094/mpmi-05-19-0122-r.

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Effector-dependent manipulation of host transcription is a key virulence mechanism used by Xanthomonas species causing bacterial spot disease in tomato and pepper. Transcription activator-like (TAL) effectors employ novel DNA-binding domains to directly activate host transcription, whereas the non-TAL effector XopD uses a small ubiquitin-like modifier (SUMO) protease activity to represses host transcription. The targets of TAL and non-TAL effectors provide insight to the genes governing susceptibility and resistance during Xanthomonas infection. In this study, we investigated the extent to whi
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Ma, Wenbo, Yuanchao Wang, and John McDowell. "Focus on Effector-Triggered Susceptibility." Molecular Plant-Microbe Interactions® 31, no. 1 (2018): 5. http://dx.doi.org/10.1094/mpmi-11-17-0275-le.

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Effector biology exhibits diversity at every level. Effector proteins play key roles in the molecular interplay between plants and plant-associated organisms, and effector biology remains one of the most active areas in the research field of molecular plant-microbe interactions. Using effectors as probes, much has been learned about pathogen virulence and host immunity, which has broad implications in developing disease-resistant crops that are essential for global food security. Thus, the MPMI Editorial Board is publishing this Focus Issue to showcase recent progress in this area. Additional
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Zhan, Jun, Maria Johnson Irudayam, Yukio Nakamura, Ryo Kurita, and Arthur W. Nienhuis. "High level of fetal-globin reactivation by designed transcriptional activator-like effector." Blood Advances 4, no. 4 (2020): 687–95. http://dx.doi.org/10.1182/bloodadvances.2019000482.

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Abstract The fetal-to-adult hemoglobin switch has been a focus of a long-standing effort to potentially treat sickle cell disease and β thalassemia by induction of fetal hemoglobin. In a continuation of this effort, we designed specific transcriptional activator-like effectors (TALEs) to target both the Gγ and Aγ-globin promoters. We fused the TALEs to a LIM domain binding protein (Ldb1) dimerization domain, followed by a T2A green fluorescent protein (GFP) cassette, which were assembled into a lentiviral vector. To prevent deletions caused by the repeats of TALEs during the lentivirus packing
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Shen, D. K., D. Filopon, L. Kuhn, B. Polack, and B. Toussaint. "PsrA Is a Positive Transcriptional Regulator of the Type III Secretion System in Pseudomonas aeruginosa." Infection and Immunity 74, no. 2 (2006): 1121–29. http://dx.doi.org/10.1128/iai.74.2.1121-1129.2006.

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ABSTRACT The type III secretion system (TTSS) of Pseudomonas aeruginosa is induced in vivo upon contact with eukaryotic cells and in vitro by calcium depletion in culture medium. We have observed a previously identified protein, PsrA, necessary for full activation of TTSS gene expression in P. aeruginosa. Electrophoretic mobility shift assays showed that recombinant PsrA could bind to the exsCEBA promoter region. A mutant with a deletion in the psrA gene was constructed. Using transcriptional fusions, we demonstrated that PsrA is required for the full activation of transcription of the TTSS re
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Li, Yu-Rong, Yi-Zhou Che, Hua-Song Zou, et al. "Hpa2 Required by HrpF To Translocate Xanthomonas oryzae Transcriptional Activator-Like Effectors into Rice for Pathogenicity." Applied and Environmental Microbiology 77, no. 11 (2011): 3809–18. http://dx.doi.org/10.1128/aem.02849-10.

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ABSTRACTXanthomonas oryzaepv. oryzicola, the causative agent of bacterial leaf streak, injects a plethora of effectors through the type III secretion system (T3SS) into rice cells to cause disease. The T3SS, encoded by thehrpgenes, is essential for the pathogen to elicit the hypersensitive response (HR) in nonhost tobacco and for pathogenicity in host rice. Whether or not a putative lytic transglycosylase, Hpa2, interacts with a translocon protein, HrpF, to facilitate bacterial pathogenicity remains unknown. Here we demonstrated that both thehpa2andhrpFgenes are required for the pathogenicity
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Ferguson, Carolyn, Matthew McKay, R. Adron Harris, and Gregg E. Homanics. "Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation." Alcohol 47, no. 8 (2013): 595–99. http://dx.doi.org/10.1016/j.alcohol.2013.09.043.

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Ji, Zhi-Yuan, Muhammad Zakria, Li-Fang Zou, et al. "Genetic Diversity of Transcriptional Activator-Like Effector Genes in Chinese Isolates of Xanthomonas oryzae pv. oryzicola." Phytopathology® 104, no. 7 (2014): 672–82. http://dx.doi.org/10.1094/phyto-08-13-0232-r.

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Xanthomonas oryzae pv. oryzicola causes bacterial leaf streak (BLS), a devastating disease of rice in Asia countries. X. oryzae pv. oryzicola utilizes repertoires of transcriptional activator-like effectors (TALEs) to manipulate host resistance or susceptibility; thus, TALEs can determine the outcome of BLS. In this report, we studied genetic diversity in putative tale genes of 65 X. oryzae pv. oryzicola strains that originated from nine provinces of southern China. Genomic DNAs from the 65 strains were digested with BamHI and hybridized with an internal fragment of avrXa3, a tale gene origina
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García-Cano, Elena, Hagit Hak, Shimpei Magori, Sondra G. Lazarowitz, and Vitaly Citovsky. "The Agrobacterium F-Box Protein Effector VirF Destabilizes the Arabidopsis GLABROUS1 Enhancer/Binding Protein-Like Transcription Factor VFP4, a Transcriptional Activator of Defense Response Genes." Molecular Plant-Microbe Interactions® 31, no. 5 (2018): 576–86. http://dx.doi.org/10.1094/mpmi-07-17-0188-fi.

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Agrobacterium-mediated genetic transformation not only represents a technology of choice to genetically manipulate plants, but it also serves as a model system to study mechanisms employed by invading pathogens to counter the myriad defenses mounted against them by the host cell. Here, we uncover a new layer of plant defenses that is targeted by A. tumefaciens to facilitate infection. We show that the Agrobacterium F-box effector VirF, which is exported into the host cell, recognizes an Arabidopsis transcription factor VFP4 and targets it for proteasomal degradation. We hypothesize that VFP4 r
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Read, Andrew C., Mathilde Hutin, Matthew J. Moscou, Fabio C. Rinaldi, and Adam J. Bogdanove. "Cloning of the Rice Xo1 Resistance Gene and Interaction of the Xo1 Protein with the Defense-Suppressing Xanthomonas Effector Tal2h." Molecular Plant-Microbe Interactions® 33, no. 10 (2020): 1189–95. http://dx.doi.org/10.1094/mpmi-05-20-0131-sc.

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The Xo1 locus in the heirloom rice variety Carolina Gold Select confers resistance to bacterial leaf streak and bacterial blight, caused by Xanthomonas oryzae pv. oryzicola and X. oryzae pv. oryzae, respectively. Resistance is triggered by pathogen-delivered transcription activator-like effectors (TALEs) independent of their ability to activate transcription and is suppressed by truncated variants called truncTALEs, common among Asian strains. By transformation of the susceptible variety Nipponbare, we show that one of 14 nucleotide-binding, leucine-rich repeat (NLR) protein genes at the locus
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Yang, Feng-Juan, Li-Li Cheng, Ling Zhang, et al. "Y4lO of Rhizobium sp. Strain NGR234 Is a Symbiotic Determinant Required for Symbiosome Differentiation." Journal of Bacteriology 191, no. 3 (2008): 735–46. http://dx.doi.org/10.1128/jb.01404-08.

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ABSTRACT Type 3 (T3) effector proteins, secreted by nitrogen-fixing rhizobia with a bacterial T3 secretion system, affect the nodulation of certain host legumes. The open reading frame y4lO of Rhizobium sp. strain NGR234 encodes a protein with sequence similarities to T3 effectors from pathogenic bacteria (the YopJ effector family). Transcription studies showed that the promoter activity of y4lO depended on the transcriptional activator TtsI. Recombinant Y4lO protein expressed in Escherichia coli did not acetylate two representative mitogen-activated protein kinase kinases (human MKK6 and MKK1
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Dissertations / Theses on the topic "Transcriptional activator-like effector"

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Peng, Zhao. "Contribution of TAL effectors in Xanthomonas to diseases of rice and wheat." Diss., Kansas State University, 2015. http://hdl.handle.net/2097/20443.

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Doctor of Philosophy<br>Plant Pathology<br>Frank F. White<br>Rice and wheat are two major crops that suffer losses from the diseases of bacterial blight and bacterial leaf streak, which are caused by Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas translucens pv. undulosa (Xtu), respectively. Transcriptional-Activator Like (TAL) effectors, a special family of type III effector proteins from Xanthomonas, have been demonstrated as critical virulence factors that act by inducing corresponding susceptibility (S) genes in several disease complexes of plants. In this study, I analyzed the contri
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Waltl, Laura [Verfasser]. "Generation and characterization of transcription activator-like effector nucleases / Laura Waltl." Gießen : Universitätsbibliothek, 2016. http://d-nb.info/1102854069/34.

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Kubik, Grzegorz [Verfasser]. "Deciphering Epigenetic Cytosine Modifications with Transcription Activator Like Effector Proteins / Grzegorz Kubik." Konstanz : Bibliothek der Universität Konstanz, 2016. http://d-nb.info/1112337008/34.

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辻, 将吾. "分子進化法によるTranscription activator-like effectorの機能拡張". 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225531.

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Zhang, Junli. "Functional analysis of bacterial TAL effectors and the targeted susceptibility genes in plants." Diss., Kansas State University, 2015. http://hdl.handle.net/2097/20361.

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Doctor of Philosophy<br>Department of Plant Pathology<br>Frank White<br>The genus Xanthomonas consists of bacterial species causing economically important plant diseases in major crops. In a wide variety of Xanthamonas species, the transcription activator-like (TAL) effectors (proteins) are synthesized and secreted into host cells, whereby they enter the plant nucleus. TAL effectors bind specific host gene promoters, inducing the expression of the targeted genes, which in some cases leads to either resistance or an enhanced state of disease susceptibility. The TAL effectors in individual Xanth
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Habierski, Andre [Verfasser]. "Die in vitro-Modifikation des kaninen ß-Galaktosidase-Gens mittels Zinkfingernukleasen und transcription activator like effector nucleases / Andre Habierski." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2014. http://d-nb.info/106486306X/34.

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Maeder, Morgan Lee. "Engineered DNA-Binding Proteins for Targeted Genome Editing and Gene Regulation." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:10770.

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Engineered DNA-binding proteins enable targeted manipulation of the genome. Zinc fingers are the most well characterized DNA-binding domain and for many years research has focused on understanding and manipulating the sequence-specificities of these proteins. Recently, major advances in the ability to engineer zinc finger proteins, as well as the discovery of a new class of DNA-binding domains - transcription activator-like effectors (TALEs), have made it possible to rapidly and reliably engineer proteins targeted to any sequence of interest. With this capability, focus has shifted to explo
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Moreira, Catarina Alfaya. "DESENVOLVIMENTO DE PROTEÍNA SINTÉTICA QUIMÉRICA BASEADA EM TALE (TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR) PARA APLICAÇÃO EM SISTEMA BIOSSENSOR DE DNA. 72f 2017." Instituto de Ciências da Saúde, 2017. http://repositorio.ufba.br/ri/handle/ri/25293.

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Submitted by Hiolanda Rêgo (hiolandarego@gmail.com) on 2018-02-05T18:15:30Z No. of bitstreams: 1 Dissertação_ICS_Catarina Alfaya Moreira.pdf: 3840507 bytes, checksum: 842c5cfecee2c3b039e0c031feb67016 (MD5)<br>Made available in DSpace on 2018-02-05T18:15:30Z (GMT). No. of bitstreams: 1 Dissertação_ICS_Catarina Alfaya Moreira.pdf: 3840507 bytes, checksum: 842c5cfecee2c3b039e0c031feb67016 (MD5)<br>As abordagens de Biologia Sintética possuem potencial de aumentar a produção de ferramentas diagnósticas adequadas para utilização na prática, como os biossensores de DNA. O controle dos sistemas biol
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Rathi, Preeti [Verfasser], Daniel [Akademischer Betreuer] Summerer, and Leif [Gutachter] Dehmelt. "Isolation of genomic DNA sequences with expanded nucleobase selectivity using Transcription Activator-Like Effector Proteins / Preeti Rathi ; Gutachter: Leif Dehmelt ; Betreuer: Daniel Summerer." Dortmund : Universitätsbibliothek Dortmund, 2017. http://d-nb.info/1160443246/34.

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Gieß, Mario David [Verfasser], Daniel [Akademischer Betreuer] Summerer, and Daniel [Gutachter] Rauh. "Chemoselective conjugation strategies for the programmable detection of epigenetic cytosine 5-modifications with transcription activator-like effectors / Mario David Gieß ; Gutachter: Daniel Rauh ; Betreuer: Daniel Summerer." Dortmund : Universitätsbibliothek Dortmund, 2019. http://d-nb.info/1195777272/34.

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Book chapters on the topic "Transcriptional activator-like effector"

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Buchmuller, Benjamin, Álvaro Muñoz-López, Mario Gieß, and Daniel Summerer. "Design and Application of DNA Modification-Specific Transcription-Activator-Like Effectors." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0876-0_29.

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Taheri-Ghahfarokhi, Amir, Luis F. Malaver-Ortega, and Huseyin Sumer. "Genome Modification of Pluripotent Cells by Using Transcription Activator-Like Effector Nucleases (TALENs)." In Methods in Molecular Biology. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2848-4_19.

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Hummel, Aaron W., and Adam J. Bogdanove. "The Roles of Transcription Activator-Like (TAL) Effectors in Virulence and Avirulence ofXanthomonas." In Molecular Plant Immunity. Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781118481431.ch6.

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Ochiai, Hiroshi, and Takashi Yamamoto. "Genome Editing Using Zinc-Finger Nucleases (ZFNs) and Transcription Activator-Like Effector Nucleases (TALENs)." In Targeted Genome Editing Using Site-Specific Nucleases. Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-55227-7_1.

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Schreiber, Tom, and Alain Tissier. "Synthetic Transcription Activator-Like Effector-Activated Promoters for Coordinated Orthogonal Gene Expression in Plants." In Molecular Pharming. John Wiley & Sons, Inc., 2018. http://dx.doi.org/10.1002/9781118801512.ch2.

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Van Nieuwenhuysen, Tom, and Kris Vleminckx. "Targeted Genome Engineering in Xenopus Using the Transcription Activator-Like Effector Nuclease (TALEN) Technology." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8784-9_4.

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S. Dev, Sona, Jini Joseph, and Ligi Lambert D’Rosario. "Prospects for Genome Editing of Potato." In Solanum tuberosum - a Promising Crop for Starvation Problem [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99278.

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Potato (Solanum tuberosum L.) is a staple food crop that could play a major role in improving food security in developing nations. The sustainable production of this crop faces many challenges like pests, diseases, abiotic stresses and post-harvest problems. Transgenic technology and gene silencing strategies offered a new hope of solution to the conventional time consuming breeding programmes. However the genetically modified crops are affected by regulatory approvals and safety concerns. In this aspect, gene editing techniques like ZFNs (zinc-finger nucleases), TALENs (transcription activator-like effector nucleases), and CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR associated Cas9), offer better choice for production of transgene and marker free disease resistant potatoes.
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Betul Kaya, Hilal, Rhitu Rai, and Adam J. Bogdanove. "Using TALENs for genome editing in plants." In Genome editing for precision crop breeding. Burleigh Dodds Science Publishing, 2021. http://dx.doi.org/10.19103/as.2020.0082.02.

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Transcription activator-like effector nucleases (TALENs) are powerful tools for precise and efficient locus-specific editing. Among the various genome editing tools that were developed prior to the CRISPR/Cas system, TALENs have been the most widely used, and they remain worthy of consideration due to their unique targeting properties and the current intellectual property landscape, which give them distinct advantages over CRISPR/Cas for some applications. This chapter briefly reviews and discusses use of TALENs in plants including their important distinguishing features, as well as design principles and tools, methods for construct assembly, and other available resources to assist researchers using this technology.
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"CHAPTER 8: Transcription Activator-Like Effectors: From Pathogenesis to Targeted Genome Editing." In Virulence Mechanisms of Plant-Pathogenic Bacteria, edited by Bing Yang and Frank F. White. The American Phytopathological Society, 2016. http://dx.doi.org/10.1094/9780890544495.008.

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Zobrist, Jacob D., Morgan McCaw, Minjeong Kang, Alan L. Eggenberger, Keunsub Lee, and Kan Wang. "Genome editing of maize." In Genome editing for precision crop breeding. Burleigh Dodds Science Publishing, 2021. http://dx.doi.org/10.19103/as.2020.0082.19.

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Developed over thousands of years largely through human intervention, the modern maize genome can now be precisely modified for agricultural improvement and scientific research. This chapter focuses on progress made in recent decades utilizing site-specific nuclease (SSN) technologies in maize genome engineering. Many SSNs, such as meganucleases, zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated proteins (Cas) have been used in maize for both functional analysis and trait improvement. The chapter summarizes the recent innovations related to maize genome editing using SSN technologies, the type of approaches, target genes and traits, and reagent delivery methods. It also discusses the current challenges as well as potential improvements for maize genome engineering protocols.
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Conference papers on the topic "Transcriptional activator-like effector"

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Lee, Sanghoon, Changhong Yin, Timmy O'Connell, Janet Ayello, Carmella van de Ven, and Mitchell S. Cairo. "Abstract 3112: Transcription activator-like effector nucleases (TALENs) mediated silencing of Bruton's tyrosine kinase (BTK) inhibits phosphorylation of Erk in Burkitt lymphoma." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3112.

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Mohbeddin, Abeer, Nawar Haj Ahmed, and Layla Kamareddine. "The use of Drosophila Melanogaster as a Model Organism to study the effect of Innate Immunity on Metabolism." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0224.

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Apart from its traditional role in disease control, recent body of evidence has implicated a role of the immune system in regulating metabolic homeostasis. Owing to the importance of this “immune-metabolic alignment” in dictating a state of health or disease, a proper mechanistic understanding of this alignment is crucial in opening up for promising therapeutic approaches against a broad range of chronic, metabolic, and inflammatory disorders like obesity, diabetes, and inflammatory bowel syndrome. In this project, we addressed the role of the Janus kinase/signal transducer and activator of tr
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