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Journal articles on the topic 'Transfer and registration, Switzerland: Vaud'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Levi, Fabio, Van-Cong Te, Lalao Randimbison, and Carlo La Vecchia. "Cancer incidence registration and trends in the Canton of Vaud, Switzerland." European Journal of Cancer and Clinical Oncology 27, no. 2 (1991): 207–9. http://dx.doi.org/10.1016/0277-5379(91)90489-z.

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Franceschi, Silvia, Fabio Levi, Isabelle Rolland-Portal, and Carlo La Vecchia. "Linkage of death certification of AIDS and cancer registration in Vaud, Switzerland." European Journal of Cancer 28, no. 8-9 (1992): 1487–90. http://dx.doi.org/10.1016/0959-8049(92)90550-l.

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Zimmermann, Petra, Salome Kurth, Stamatios Giannoukos, Martin Stocker, and Nicholas A. Bokulich. "NapBiome trial: Targeting gut microbiota to improve sleep rhythm and developmental and behavioural outcomes in early childhood in a birth cohort in Switzerland – a study protocol." BMJ Open 15, no. 3 (2025): e092938. https://doi.org/10.1136/bmjopen-2024-092938.

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IntroductionThe gut–brain axis plays a crucial role in the regulation and development of psychological and physical processes. The first year of life is a critical period for the development of the gut microbiome, which parallels important milestones in establishing sleep rhythm and brain development. Growing evidence suggests that the gut microbiome influences sleep, cognition and early neurodevelopment. For term-born and preterm-born infants, difficulties in sleep regulation may have consequences on health. Identifying effective interventions on the gut–brain axis in early life is likely to

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Amador-Fernández, Noelia, Mathilde Escaith, Elodie Simi, Patricia Quintana-Bárcena, and Jérôme Berger. "Evaluation of an enhanced service for medication review with follow up in Swiss community pharmacies: Pre-post study protocol." PLOS ONE 18, no. 10 (2023): e0292037. http://dx.doi.org/10.1371/journal.pone.0292037.

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Background In Switzerland, 20,000 people are hospitalized each year as result of drug related problems (DRPs). The sources of DRPs can be related to patients’ behavior (i.e., wrong administration) or to health processes (i.e., drug-drug interaction). No community pharmacy (CP) service focus on DRPs related to patients’ behavior is currently recognized or remunerated in Switzerland. A medication review with follow up (MRF) has been developed to evaluate prescription and non-prescription medication. Objective To evaluate the impact of MRF service for the identification and management DRPs associ

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Chatelan, Angeline, Pedro Marques-Vidal, Sabine Bucher, et al. "Lessons Learnt About Conducting a Multilingual Nutrition Survey in Switzerland: Results from menuCH Pilot Survey." International Journal for Vitamin and Nutrition Research 87, no. 1-2 (2017): 25–36. http://dx.doi.org/10.1024/0300-9831/a000429.

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This paper informs about the implementation of the first trilingual Swiss nutrition pilot survey and lessons learnt in terms of recruitment, participation, data collection feasibility, and data management. The population-based cross-sectional nutrition pilot survey took place between June and November 2013. Six trained dietitians interviewed 276 adults aged 18-75 years residing in the cantons of Bern (German), Vaud (French) or Ticino (Italian). Food consumption was assessed with two non-consecutive computer-assisted 24-Hour Dietary Recalls (24HDR), applying a trilingual version of GloboDiet® a

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Birkhäuser, Veronika, Martina D. Liechti, Collene E. Anderson, et al. "TASCI—transcutaneous tibial nerve stimulation in patients with acute spinal cord injury to prevent neurogenic detrusor overactivity: protocol for a nationwide, randomised, sham-controlled, double-blind clinical trial." BMJ Open 10, no. 8 (2020): e039164. http://dx.doi.org/10.1136/bmjopen-2020-039164.

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IntroductionNeurogenic lower urinary tract dysfunction (NLUTD), including neurogenic detrusor overactivity (NDO) and detrusor sphincter dyssynergia, is one of the most frequent and devastating sequelae of spinal cord injury (SCI), as it can lead to urinary incontinence and secondary damage such as renal failure. Transcutaneous tibial nerve stimulation (TTNS) is a promising, non-invasive neuromodulatory intervention that may prevent the emergence of the C-fibre evoked bladder reflexes that are thought to cause NDO. This paper presents the protocol for TTNS in acute SCI (TASCI), which will evalu

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Di Bernardo, Stefano, Yvan Mivelaz, Adina Mihaela Epure, et al. "Assessing the consequences of gestational diabetes mellitus on offspring’s cardiovascular health: MySweetHeart Cohort study protocol, Switzerland." BMJ Open 7, no. 11 (2017): e016972. http://dx.doi.org/10.1136/bmjopen-2017-016972.

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IntroductionGestational diabetes mellitus (GDM) is a state of glucose intolerance with onset during pregnancy. GDM carries prenatal and perinatal risks as well as long-term risks for the mother and her child. GDM may be involved in the foetal programming of long-term cardiovascular health. However, evidence is sparse and the effect of GDM on cardiovascular health is unknown. To address these issues, we will conduct MySweetHeart Cohort study. The objectives are to assess the effect of GDM on offspring’s cardiovascular health early in life by using surrogate markers of cardiovascular disease and

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Rexhaj, Shyhrete, Shadya Monteiro, Philippe Golay, Claire Coloni-Terrapon, Daniel Wenger, and Jérôme Favrod. "Ensemble programme for early intervention in informal caregivers of psychiatric adult patients: a protocol for a randomised controlled trial." BMJ Open 10, no. 7 (2020): e038781. http://dx.doi.org/10.1136/bmjopen-2020-038781.

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IntroductionInformal caregivers play a major role in the support and maintenance of community patients with severe psychiatric disorders. A pilot study showed that an individualised brief intervention such as the Ensemble programme leads to significant improvements in psychological health state and optimism.Methods and analysisThis randomised controlled trial aims to compare the efficacy of using Ensemble in improving informal caregivers’ psychological health states and the ability to play an active role in their situations with that of support as usual. Improvements on the psychological healt

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Savoy, Simon, Pierre-Nicolas Carron, Nathalie Romain-Glassey, and Nicolas Beysard. "Self-Reported Violence Experienced by Swiss Prehospital Emergency Care Providers." Emergency Medicine International 2021 (December 17, 2021): 1–6. http://dx.doi.org/10.1155/2021/9966950.

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Background. Workplace violence is a serious and increasing problem in health care. Nevertheless, only few studies were carried out concerning this topic and then mainly in English-speaking countries. The objectives were to describe the acts of violence experienced by prehospital emergency care providers (PECPs) in the western part of Switzerland between January and December 2016 and to assess the consequences for subsequent PECPs behaviors. Methods. An observational cross-sectional study, carried out using an online survey, has been sent to all 416 PECPs in the Canton of Vaud, in the western,

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Plys, Ekaterina, Jean-Luc Bulliard, Aziz Chaouch, et al. "Colorectal Cancer Screening Decision Based on Predicted Risk: Protocol for a Pilot Randomized Controlled Trial." JMIR Research Protocols 12 (September 7, 2023): e46865. http://dx.doi.org/10.2196/46865.

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Background Incidence of and mortality from colorectal cancer (CRC) can be effectively reduced by screening with the fecal immunochemical test (FIT) or colonoscopy. Individual risk to develop CRC within 15 years varies from <1% to >15% among people aged 50 to 75 years. Communicating personalized CRC risk and appropriate screening recommendations could improve the risk-benefit balance of screening test allocations and optimize the use of limited colonoscopy resources. However, significant uncertainty exists regarding the feasibility and efficacy of risk-based screening. Objective We aim to

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Chanvrier, Hélène, Valentine Rattaz, Valentin Offredi, Marc Dupuis, and Antje Horsch. "Swiss cohort on Traumatic Childbirth and Health (SwiTCH): protocol for a prospective, population-based cohort study on parents’ mental health from pregnancy to one year postpartum." BMJ Open 14, no. 1 (2024): e080557. http://dx.doi.org/10.1136/bmjopen-2023-080557.

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IntroductionApproximately 4%–5% of mothers develop childbirth-related post-traumatic stress disorder (CB-PTSD) and approximately 12.3% of mothers develop some CB-PTSD symptoms (CB-PTSS). To date, there is a dearth of studies on fathers and other coparents. Parental CB-PTSD and CB-PTSS may have a negative impact not only on the parents but also on the infant. Understanding risk and protective factors of CB-PTSD for both parents and its consequences on the family is key to detecting or anticipating it, to developing interventions aimed at reducing its detrimental effects and to supporting parent

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Santos, Gabrielle Cécile, Maria Liljeroos, Roger Hullin, et al. "SYMPERHEART: an intervention to support symptom perception in persons with heart failure and their informal caregiver: a feasibility quasi-experimental study protocol." BMJ Open 11, no. 7 (2021): e052208. http://dx.doi.org/10.1136/bmjopen-2021-052208.

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IntroductionSymptom perception in heart failure (HF) has been identified as crucial for effective self-care, and is related to patient and health system outcomes. There is uncertainty regarding the feasibility and acceptability of symptom perception support and doubts regarding how to include informal caregivers. This study aims to test the feasibility, acceptability and outcome responsiveness of an intervention supporting symptom perception in persons with HF and their informal caregiver.Methods and analysisA feasibility study with a quasi-experimental pretest and post-test single group desig

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Ortoleva Bucher, Claudia, Maryline Abt, Laurent Berthoud, and Christine Cohen. "Health and coping strategies of nursing home residents and their relatives during the COVID-19 pandemic: a mixed-methods study protocol." BMJ Open 12, no. 3 (2022): e059262. http://dx.doi.org/10.1136/bmjopen-2021-059262.

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IntroductionThe COVID-19 pandemic hit older adults particularly hard, especially those living in nursing homes. The present study’s primary aim is to quantify the states of physical and mental health of nursing home residents and their relatives following the implementation of the exceptional confinement measures. The secondary aim is to explore the lived experiences of the stressors perceived by older adults and their relatives, as well as the support strategies implemented by health professionals and their results.Methods and analysisWe chose a mixed-methods (quantitative/qualitative) study

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Fort, Déborah, Camille Deforges, Nadine Messerli-Bürgy, et al. "Tackling childbirth-related intrusive memories with a single-session behavioural intervention involving a visuospatial task: protocol for a single-blind, waitlist-controlled randomised trial." BMJ Open 13, no. 5 (2023): e073874. http://dx.doi.org/10.1136/bmjopen-2023-073874.

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IntroductionApproximately 12.3% of mothers experience childbirth-related post-traumatic stress symptoms (CB-PTSS). However, evidence-based interventions to treat CB-PTSS are lacking. Intrusive memories (IM), a key CB-PTSS, are distressing and can trigger other PTSS by reliving the traumatic event. Emerging evidence shows that a behavioural intervention involving a visuospatial task (BI-VT) can reduce the number of IM and PTSS, supposedly by interfering with the reconsolidation of the trauma memory. This study aims to test the efficacy of a single-session BI-VT targeting IM to reduce the number

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Hafner, Albert, Mirco Brunner та Julian Laabs. "Археологія альпійського простору. Дослідження передгір'їв, долинних систем та високогірних ландшафтів Альп / Archaeology of the Alpine space. Research on the foothills, valley systems and high mountain landscapes of the Alps". VITA ANTIQUA 9, HUMAN & LANDSCAPE: Prehistoric Archaeology of Eastern Europe (2017): 16–37. https://doi.org/10.5281/zenodo.1240724.

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В даній статті наводяться приклади ландшафтних археологічних досліджень в альпійському регіонально- му контексті. Як навколо, так і в самих Європейських Альпах ландшафти відзначаються великою різноманітніс- тю. Найбільш істотні ландшафтні відмінності спостерігаються на висотах, що мають відмітки від 400 до 3000 і більше метрів над рівнем моря. Основними топографічними ознаками регіону являються горбисті альпійські передгір’я, широкі внутрішні долини, що заходять далеко в самі Альпи та високогірні зони, які починаються вище лінії деревної рослинності. В статті наводяться приклади, що тема

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Bandiera, Carole, Jennifer Dotta-Celio, Isabella Locatelli, et al. "Interprofessional Medication Adherence Program for Patients With Diabetic Kidney Disease: Protocol for a Randomized Controlled and Qualitative Study (PANDIA-IRIS)." JMIR Research Protocols 10, no. 3 (2021): e25966. http://dx.doi.org/10.2196/25966.

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Background Despite effective treatments, more than 30% of patients with diabetes will present with diabetic kidney disease (DKD) at some point. Patients with DKD are among the most complex as their care is multifactorial and involves different groups of health care providers. Suboptimal adherence to polypharmacy is frequent and contributes to poor outcomes. As self-management is one of the keys to clinical success, structured medication adherence programs are crucial. The PANDIA-IRIS (patients diabétiques et insuffisants rénaux: un programme interdisciplinaire de soutien à l’adhésion thérapeut

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Egger, Matthias, Mamatha Sauermann, Tom Loosli, et al. "HIV-1 subtype-specific drug resistance on dolutegravir-based antiretroviral therapy: protocol for a multicentre study (DTG RESIST)." BMJ Open 14, no. 8 (2024): e085819. http://dx.doi.org/10.1136/bmjopen-2024-085819.

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IntroductionHIV drug resistance poses a challenge to the United Nation’s goal of ending the HIV/AIDS epidemic. The integrase strand transfer inhibitor (InSTI) dolutegravir, which has a higher resistance barrier, was endorsed by the WHO in 2019 for first-line, second-line and third-line antiretroviral therapy (ART). This multiplicity of roles of dolutegravir in ART may facilitate the emergence of dolutegravir resistance.Methods and analysisNested within the International epidemiology Databases to Evaluate AIDS (IeDEA), DTG RESIST is a multicentre study of adults and adolescents living with HIV

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Kohl Schwartz, A. S., I. Calzaferri, M. Roumet, et al. "Follicular flushing leads to higher oocyte yield in monofollicular IVF: a randomized controlled trial." Human Reproduction 35, no. 10 (2020): 2253–61. http://dx.doi.org/10.1093/humrep/deaa165.

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Abstract STUDY QUESTION Does follicular flushing increase the number of mature oocytes in monofollicular IVF? SUMMARY ANSWER Follicular flushing increases the number of mature oocytes in monofollicular IVF. WHAT IS KNOWN ALREADY Flushing increases neither the oocyte yield nor the pregnancy rate in polyfollicular IVF or in poor responder patients. In monofollicular IVF, the effect of flushing has so far been addressed by two studies: (i) a prospective study with minimal stimulation IVF demonstrated an increased oocyte yield, and (ii) a retrospective study with natural cycle (NC)-IVF showed an i

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Kim, SooJeong. "Discussion on the Qualification of Virtual Assets as a Property." Korean Association of Civil Law 106 (March 31, 2024): 35–79. http://dx.doi.org/10.52554/kjcl.2024.106.35.

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Whether virtual assets can be regarded as a ‘thing’ or ‘property has been widely discussed, because it can be a prerequisite to whether legal theories in property law and in bankruptcy law would be applied to virtual assets. Although financial regulatory Acts on virtual asset law are being legislated around the world, few countries have legislated how virtual assets will be understood in civil law. In this situation, Liechtenstein has in 2019 and Switzerland has in 2021 partially regulated civil legal issues of virtual assets in their Acts and UNIDROIT adopted its principles on digital assets

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Pellet, Joanie, Marianne Weiss, Franziska Zúñiga, and Cedric Mabire. "Implementation and preliminary testing of a theory-guided nursing discharge teaching intervention for adult inpatients aged 50 and over with multimorbidity: a pragmatic feasibility study protocol." Pilot and Feasibility Studies 7, no. 1 (2021). http://dx.doi.org/10.1186/s40814-021-00812-4.

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Abstract Background Discharge teaching by nurses during hospitalization is essential to provide multimorbid inpatients with the knowledge and skills to self-manage their health conditions. However, available disease-specific teaching guidelines do not address the cumulative complexity of multiple chronic diseases that occur with greater frequency in older adults. Therefore, there is a need for a discharge teaching intervention which uses concepts that specifically address the needs of these patients, such as considering their level of activation (i.e. knowledge, skills and confidence to self-m

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Gościński, Jan, and Artur D. Kubacki. "Land Registration Concepts in Translation." International Journal for the Semiotics of Law - Revue internationale de Sémiotique juridique, November 19, 2020. http://dx.doi.org/10.1007/s11196-020-09800-y.

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AbstractLand registration systems are used throughout the world in order to store information on the ownership of land, rights attached to it, and burdens affecting it. A smoothly functioning land registration system guarantees the security of land transfer operations. However, there are significant differences in the way national land registration systems are run due to their historical development and divergent legislative approaches to land registration. Consequently, the need arises to compare different systems so as to find both common ground and discrepancies between them. The paper cont

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Determann, Lothar, Michaela Nebel, and Michael Schmidl. "The EU–US data privacy framework and the impact on companies in the EEA and USA compared to other international data transfer mechanisms." Journal of Data Protection & Privacy, December 1, 2023. http://dx.doi.org/10.69554/qunv4897.

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Third time's a charm? Companies in the European Economic Area, Switzerland and the UK (EEA+) are considering the pros and cons of the third attempt of the EU Commission and US government to establish interoperability between their data protection and privacy law systems, after the demise of the US Safe Harbor Program and the EU–US Privacy Shield. Should US companies register? Are the efforts worth the potential benefits, given that the new programme has already been challenged and may be invalidated like previous programmes for reasons that businesses cannot control? Should companies that were

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James, CE, C. Stucker, C. Junker-Tschopp, et al. "Musical and psychomotor interventions for cognitive, sensorimotor, and cerebral decline in patients with Mild Cognitive Impairment (COPE): a study protocol for a multicentric randomized controlled study." BMC Geriatrics 23, no. 1 (2023). http://dx.doi.org/10.1186/s12877-022-03678-0.

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Abstract Background Regular cognitive training can boost or maintain cognitive and brain functions known to decline with age. Most studies administered such cognitive training on a computer and in a lab setting. However, everyday life activities, like musical practice or physical exercise that are complex and variable, might be more successful at inducing transfer effects to different cognitive domains and maintaining motivation. "Body-mind exercises", like Tai Chi or psychomotor exercise, may also positively affect cognitive functioning in the elderly. We will compare the influence of active

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Cecchini, Luca, Colette Barmaz, Maria José Coloma Cea, et al. "The Bern Birth Cohort (BeBiCo) to study the development of the infant intestinal microbiota in a high-resource setting in Switzerland: rationale, design, and methods." BMC Pediatrics 23, no. 1 (2023). http://dx.doi.org/10.1186/s12887-023-04198-5.

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Abstract Background Microbiota composition is fundamental to human health with the intestinal microbiota undergoing critical changes within the first two years of life. The developing intestinal microbiota is shaped by maternal seeding, breast milk and its complex constituents, other nutrients, and the environment. Understanding microbiota-dependent pathologies requires a profound understanding of the early development of the healthy infant microbiota. Methods Two hundred and fifty healthy pregnant women (≥20 weeks of gestation) from the greater Bern area will be enrolled at Bern University ho

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Monseur, B., L. Shandley, J. Zhang, et al. "O-159 Domestic and cross-border reproductive care among same-sex male intended parents: comparing live birth rates (LBRs) in a national retrospective cohort in the United States (U.S.)." Human Reproduction 39, Supplement_1 (2024). http://dx.doi.org/10.1093/humrep/deae108.178.

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Abstract Study question How common is cross-border reproductive care (CBRC) in the U.S. among international same-sex male intended parents? Do CBRC LBRs differ compared to domestic counterparts? Summary answer A substantial number of international same-sex male intended parents seek CBRC in the U.S. LBRs per transfer are reassuring and comparable to domestic counterparts. What is known already Same-sex male intended parents often work with a gestational carrier to have a genetically related child(ren); however, restrictive and/or discriminatory policies in their home countries may prevent acce

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Vidal, A., C. Dhakal, J. Weiss, D. Lehnick, and A. Koh. Schwartz. "P–654 What is the best luteal phase support in frozen-thawed embryo transfer cycle?" Human Reproduction 36, Supplement_1 (2021). http://dx.doi.org/10.1093/humrep/deab130.653.

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Abstract Study question What is the best progesterone administration for luteal phase support (LPS) in frozen-thawed embryo transfer cycle? Summary answer Different modes of hormonal luteal phase support do not affect clinical pregnancy rate (CPR) or live birth rate (LBR) in frozen-thawed embryo transfer (FET) cycles. What is known already FET has increased substantially over the last years. To support implantation, endometrial and embryo maturities must be synchronized; therefore, endometrial and follicular maturation are monitored either within the artificial cycle. Estrogen and progesterone

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Okamoto, E., N. Enatsu, K. Yamada, et al. "P-630 Comparison of follitropin delta versus follitropin alfa in progestin-primed ovarian stimulation in IVF." Human Reproduction 38, Supplement_1 (2023). http://dx.doi.org/10.1093/humrep/dead093.958.

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Abstract Study question Is there a difference in a clinical outcome between using follitropin delta and follitropin alfa undergoing a progestin primed ovarian stimulation (PPOS) protocol? Summary answer There was no difference between follitropin delta and follitropin alfa in terms of pregnancy rates. What is known already Follitropin delta (REKOVELLE, Ferring Pharmaceuticals, Switzerland) is the first recombinant human follicle-stimulating hormone (FSH) using the algorithm-based individualized dosing regimen while reducing the risk of ovarian hyperstimulation syndrome (OHSS) as compared with

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Koh. Schwartz, A., A. Vidal, L. Fritsche, K. Nirgianakis, M. Vo. Wolff, and V. Mitter. "P–310 Women with endometriosis achieve live birth after a similar number of embryo transfers independent of the endometriosis subtype." Human Reproduction 36, Supplement_1 (2021). http://dx.doi.org/10.1093/humrep/deab130.309.

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Abstract Study question How many embryo transfers are needed to achieve the first live birth in women with endometriosis depending on disease localisation? Summary answer The number of transfers needed to achieve live birth in women with endometriosis is independent from the disease’s subtype. What is known already Infertility is one of the leading symptoms in women with endometriosis. Endometriosis is also known to negatively impact in-vitro fertilization (IVF) outcome. A reduction of oocyte yield, especially of mature oocytes in women with endometrioma (OMA) and deep infiltrating endometrios

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Makieva, S., M. K. Sachs, M. Xie, et al. "P-255 Double vitrification and warming does not impact clinical pregnancy rate in single blastocyst transfer cycles." Human Reproduction 37, Supplement_1 (2022). http://dx.doi.org/10.1093/humrep/deac107.245.

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Abstract Study question Does double vitrification and thawing impact clinical pregnancy rate after a single blastocyst transfer? Summary answer The clinical pregnancy rate obtained after double vitrification was comparable to that obtained after single vitrification. What is known already Double vitrification-warming (DVW) is commonly practiced to accommodate surplus viable embryos suitable for transfer, allow retesting of inconclusive-diagnosed blastocysts for PGT and circumvent limitations associated with national policies on embryo culture in certain countries. Despite its popularity, the e

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James, Clara E., Eckart Altenmüller, Matthias Kliegel, et al. "Train the brain with music (TBM): brain plasticity and cognitive benefits induced by musical training in elderly people in Germany and Switzerland, a study protocol for an RCT comparing musical instrumental practice to sensitization to music." BMC Geriatrics 20, no. 1 (2020). http://dx.doi.org/10.1186/s12877-020-01761-y.

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Abstract Background Recent data suggest that musical practice prevents age-related cognitive decline. But experimental evidence remains sparse and no concise information on the neurophysiological bases exists, although cognitive decline represents a major impediment to healthy aging. A challenge in the field of aging is developing training regimens that stimulate neuroplasticity and delay or reverse symptoms of cognitive and cerebral decline. To be successful, these regimens should be easily integrated in daily life and intrinsically motivating. This study combines for the first-time protocoll

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Muller, Dion R. P., Dirk J. Stenvers, Arjan Malekzadeh, Frederik Holleman, Rebecca C. Painter, and Sarah E. Siegelaar. "Effects of GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation on offspring outcomes: a systematic review of the evidence." Frontiers in Endocrinology 14 (October 10, 2023). http://dx.doi.org/10.3389/fendo.2023.1215356.

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Aims/hypothesisGlucagon-like peptide 1 (GLP-1) agonists and sodium-glucose co-transporter-2 (SGLT2) inhibitors are novel drugs which have recently seen rapid uptake in the treatment of type 2 diabetes and obesity. The paucity of data regarding their safety during pregnancy and lactation causes a dilemma for the physician. The aim of the present study was to systematically review all available data on the offspring effects of GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation.MethodsWe systematically searched PubMed, clinicaltrials.gov, FDA and EMA product information on GLP-1 a

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Neumann, Kay, Antonia Masuch, Reinhard Vonthein та ін. "Dydrogesterone and 20α-dihydrodydrogesterone plasma levels on day of embryo transfer and clinical outcome in an anovulatory programmed frozen-thawed embryo transfer cycle: a prospective cohort study". Human Reproduction, 22 березня 2022. http://dx.doi.org/10.1093/humrep/deac045.

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Abstract STUDY QUESTION What are the plasma concentrations of dydrogesterone (DYD) and its metabolite, 20α-dihydrodydrogesterone (DHD), measured on day of embryo transfer (ET) in programmed anovulatory frozen embryo transfer (FET) cycles using 10 mg per os ter-in-die (tid) oral DYD, and what is the association of DYD and DHD levels with ongoing pregnancy rate? SUMMARY ANSWER DYD and DHD plasma levels reach steady state by Day 3 of intake, are strongly correlated and vary considerably between and within individual subjects, women in the lowest quarter of DYD or DHD levels on day of FET have a r

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Blockeel, C., G. Griesinger, R. Rago, et al. "O-011 A prospective multicentre, non-interventional, real-world study to assess the pattern of use, effectiveness and safety of follitropin delta in routine clinical practice (the PROFILE study)." Human Reproduction 37, Supplement_1 (2022). http://dx.doi.org/10.1093/humrep/deac104.011.

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Abstract Study question To observe real-world utilization of algorithm-based dosing of follitropin delta in women naïve to ovarian stimulation (OS) and undergoing either in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). Summary answer Individualized dosing of follitropin delta in real-world clinical practice results in predictable ovarian response while minimizing risk of ovarian hyperstimulation syndrome (OHSS). What is known already Follitropin delta (REKOVELLE, Ferring Pharmaceuticals, Switzerland), is the first recombinant human follicle-stimulating hormone (FSH) to

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Carullo, G., S. El-Hadad, S. Makieva, et al. "P-259 Blastocysts Vitrified on Day 6 Have Comparable Live Birth Rates and Neonatal Birth Weights to that of Day 5 Blastocysts." Human Reproduction 40, Supplement_1 (2025). https://doi.org/10.1093/humrep/deaf097.567.

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Abstract Study question How do the clinical outcomes of unbiopsied single transferred blastocysts vitrified on day 6 (D6) compare to those vitrified on day 5 (D5)? Summary answer The live birth rate (LBR) and neonatal birth Weight (NB) were comparable between D5 and D6 single frozen blastocyst transfers. What is known already Studies suggest that D5 blastocysts lead to higher LBR than D6 blastocysts, likely due to endometrial-embryo asynchrony during fresh D6 transfers. However, mixed results have emerged concerning frozen blastocyst transfers. Some studies indicate that high-quality D6 blasto

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Enatsu, Y., D. Fukagawa, M. Otsuka, N. Yoshioka, K. Kuramoto, and T. Kuramoto. "P-594 Retrospective comparative study of follitropin delta vs follitropin alfa in progestin-primed ovarian stimulation (PPOS) protocol in IVF." Human Reproduction 39, Supplement_1 (2024). http://dx.doi.org/10.1093/humrep/deae108.926.

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Abstract Study question Could the individualized fixed-dose algorithm with follitropin delta show a similar pregnancy rate to conventional dosing with follitropin alfa in PPOS protocol? Summary answer Individualized fixed-dose algorithm with follitropin delta showed a similar pregnancy rate to follitropin alfa In PPOS protocol. What is known already Follitropin delta (REKOVELLE, Ferring Pharmaceuticals, Switzerland) is the first human cell line driven recombinant follicle-stimulating hormone (FSH) with an individualized fixed-dose algorithm based on serum AMH level and body weight. Follitropin

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Lass, A., and G. Lass. "P–731 Correlation between fertility rate, utilisation of ART and gross domestic product across Europe." Human Reproduction 36, Supplement_1 (2021). http://dx.doi.org/10.1093/humrep/deab130.730.

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Abstract Study question Are there any correlations between a country’s wealth determined by GDP per capita and its total fertility rate (TFR) and utilisation of ART in Europe? Summary answer There is strong correlation across Europe between GDP and utilisation of ART. This correlation does not exist when only investigating the European Economic Area (EEA) What is known already The number of documented ART cycles has increased significantly from 203,893 cycles in 1997 (first European report) to 918,159 in 2016. During the same period, growth was observed in European GDP and, to a lesser extent,

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Sordal, T., E. Ekerhovd, B. Cohlen, et al. "O-131 BEYOND: a randomised controlled trial comparing efficacy and safety of individualised follitropin delta dosing in GnRH agonist versus antagonist protocols for first ovarian stimulation cycle." Human Reproduction 38, Supplement_1 (2023). http://dx.doi.org/10.1093/humrep/dead093.158.

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Abstract Study question How does a long GnRH agonist versus a GnRH antagonist protocol affect ovarian response when using individualised fixed daily follitropin delta dose for ovarian stimulation? Summary answer BEYOND trial data demonstrates that individualised follitropin delta dosing is safe and effective in a long GnRH agonist protocol in women with AMH ≤35 pmol/L. What is known already Efficacy and safety of a fixed daily dose of follitropin delta, individualised based on bodyweight and anti-Müllerian (AMH), have been established in RCTs using a GnRH antagonist protocol. Preliminary study

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Kadam, K., D. Natu, and D. Akhani. "P-714 Unlocking better outcomes: comparing rFSh+rLH(2:1) vs. rFSH for blastocyst formation and clinical pregnancy in older women with low ovarian reserve in IVF/ICSI." Human Reproduction 40, Supplement_1 (2025). https://doi.org/10.1093/humrep/deaf097.1020.

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Abstract Study question Is Pergoveris (rFSH+rLH, 2:1) better than Gonal F (rFSH) with respect to age and AMH in women undergoing self ICSI cycles. Summary answer Clinical pregnancies are higher in women above 38 years in Pergoveris group. Pergoveris gives higher blastulation, lesser Germinal vesicle (GV) and lower Biochemical pregnancies. What is known already Patients with age &gt; 35 years and previous poor response to ovarian stimulation (OS), benefit from LH supplementation. One of the studies confirmed LH supplementation resulted in higher implantation rates independent of maternal ag

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Polyzos, N. P., F. Martinez, C. Blockeel, et al. "O-066 Transdermal testosterone prior to ovarian stimulation for in vitro fertilization in women with poor ovarian response. A multicenter multinational double-blind placebo-controlled randomized trial (The T-TRANSPORT)." Human Reproduction 38, Supplement_1 (2023). http://dx.doi.org/10.1093/humrep/dead093.080.

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Abstract Study question Does administration of 2 months of transdermal testosterone prior to ovarian stimulation for IVF/ICSI increase clinical pregnancy rates in Bologna criteria poor ovarian responders? Summary answer Pre-treatment with 5.5mg testosterone for 2 months prior to ovarian stimulation for IVF/ICSI does not increase clinical pregnancy rates as compared with placebo. What is known already The role of androgens in the treatment of infertile women has been extensively investigated over the last 20 years. Early animal studies and small human studies supported a potentially beneficial

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Lobo, Rita, Terje Soerdal, Erling Ekerhovd, et al. "BEYOND: a randomized controlled trial comparing efficacy and safety of individualized follitropin delta dosing in a GnRH agonist versus antagonist protocol during the first ovarian stimulation cycle." Human Reproduction, May 9, 2024. http://dx.doi.org/10.1093/humrep/deae092.

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Abstract STUDY QUESTION How does a gonadotrophin-releasing hormone (GnRH) agonist versus a GnRH antagonist protocol affect ovarian response when using an individualized fixed daily dose of follitropin delta for ovarian stimulation? SUMMARY ANSWER The BEYOND trial data demonstrate thatindividualized fixed-dose follitropin delta is effective when used in a GnRH agonist protocol, compared with a GnRH antagonist protocol, in women with anti-Müllerian hormone (AMH) ≤35 pmol/l and no increased risk of ovarian hyperstimulation syndrome (OHSS). WHAT IS KNOWN ALREADY The efficacy and safety of an indiv

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