Relevant bibliographies by topics / Transformed cell

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Transformed cell'

Author: Grafiati
Published: 4 June 2021
Last updated: 4 February 2022

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Journal articles on the topic "Transformed cell"

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LeBrasseur, Nicole. "Transformed fusions." Journal of Cell Biology 171, no. 3 (November 7, 2005): 404. http://dx.doi.org/10.1083/jcb1713iti1.

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Lewis, Andrew M., David W. Alling, Steven M. Banks, Silvia Soddu, and James L. Cook. "Evaluating virus-transformed cell tumorigenicity." Journal of Virological Methods 79, no. 1 (April 1999): 41–50. http://dx.doi.org/10.1016/s0166-0934(98)00182-7.

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Aldhous, Peter. "Transformed: The stem cell breakthrough." New Scientist 198, no. 2654 (May 2008): 40–43. http://dx.doi.org/10.1016/s0262-4079(08)61103-3.

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RYAN, CIARA A., NEIL V. McFERRAN, BRIAN WALKER, and M. ISLA HALLIDAY. "56 Cytokine processing by transformed and non-transformed cell types." Biochemical Society Transactions 26, no. 1 (February 1, 1998): S46. http://dx.doi.org/10.1042/bst026s046.

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Moreira, José. "Cell of the month: Transformed human epithelial cells." Nature Cell Biology 6, no. 12 (December 2004): 1163. http://dx.doi.org/10.1038/ncb1204-1163.

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Wells, William A. "Notch gets transformed." Journal of Cell Biology 163, no. 4 (November 24, 2003): 689. http://dx.doi.org/10.1083/jcb1634iti4.

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Fox, Margaret. "Cancer cell 1: The transformed phenotype." Trends in Biochemical Sciences 10, no. 2 (February 1985): 84. http://dx.doi.org/10.1016/0968-0004(85)90242-7.

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Mesnil, Marc, Ruggero Montesano, and Hiroshi Yamasaki. "Intercellular communication of transformed and non-transformed rat liver epithelial cells." Experimental Cell Research 165, no. 2 (August 1986): 391–402. http://dx.doi.org/10.1016/0014-4827(86)90593-8.

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Santos, Carlos, Karen Chandler, Stephen Zimmer, Paul B. Fisher, Ursula Gunthert, and Kimberly Ward Anderson. "Detachment of transformed cells." Cell Biophysics 26, no. 1 (February 1995): 1–19. http://dx.doi.org/10.1007/bf02820884.

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Shapovalov, George, V’yacheslav Lehen’kyi, Roman Skryma, and Natalia Prevarskaya. "TRP channels in cell survival and cell death in normal and transformed cells." Cell Calcium 50, no. 3 (September 2011): 295–302. http://dx.doi.org/10.1016/j.ceca.2011.05.006.

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Dissertations / Theses on the topic "Transformed cell"

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Palovuori, R. (Riitta). "Regulation of cell-cell adhesion and actin cytoskeleton in non-transformed and transformed epithelial cells." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514269306.

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Abstract Epithelial cell-cell adhesions have a critical role in morphogenesis, establishment and maintenance of tissue architecture, cell-cell communication, normal cell growth and differentiation. These adhesions are disrupted during malignant transformation and tumour cell invasion. Several kinases, phosphatases and small GTPases regulate cell-cell contacts. In the present work we investigated the dynamics of cell-cell adhesion structures after microinjection of fluorophore tagged vinculin, during transformation caused by an active Src tyrosine kinase and during Helicobacter pylori infection. The regulatory role of Rac GTPase as well as the behaviour of actin and cadherin were analysed in all these conditions. Microinjection of vinculin into bovine kidney epithelial MDBK cells induced release of actin, cadherin and plakoglobin to cytoplasm of the cells, caused disruption of protein complexes at adherens and tight junctions that finally led to formation of polykaryons. Activated Rac GTPase, in turn, enhanced accumulation of cadherin to membranes and thereby diminished the formation of polykaryons, whereas inactive Rac removed cadherin from membranes. Incorporation of vinculin to lateral membranes took place also in acidifying and depolarising conditions where cell fusions were prevented. Thus, the membrane potential seemed to control fusion ability. In src-MDCK cells, activation of Src kinase led to disintegration of adherens junctions. Clusters of junctional components and bundles of actin were seen at the basal surface already within 30 min after Src activation. p120ctn was the only component of adherens junction whose relocation correlated to its phosphorylation. Inhibition of Src by a specific inhibitor PP2 restored the cubic morphology of the cells and accumulated cadherin back to lateral walls. Still p120ctn remained in cytoplasm and thereby was not responsible for the epithelial phenotype. Activation of Rac GTPase by Tiam1 also increased the amount of cadherin at lateral membranes and maintained the morphology of src-MDCK cells practically normal after activation of Src kinase. In the same way, actin cytoskeleton was reorganised in gastric carcinoma cells in response to infection with H. pylori via activation of Rac signalling pathway. Hence, Rac and cadherin seem to be the major players in the maintenance of epithelial cell morphology.
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Bowles, Paul Anthony. "Natural killer cell recognition and killing of virally-transformed and cancer cells." Thesis, University of Leeds, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550269.

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Natural Killer (NK) cells are important in the elimination of virally-infected and cancer cells. NK cell recognise changes in surface molecules on cells, which can cause an NK cell to kill the target cell by either ligation of death receptors or perforin-mediated release of granzymes. Granzymes are serine proteases that cleave numerous cellular proteins that are important in co-ordinating cell death in the target cell. Induction of apoptosis involves dysregulation of cellular machinery including disruption of mitochondrial membrane potential, nuclear fragmentation and cell membrane permeability. Here I have analysed the differences in NK cell susceptibility of human cells transformed with either the adenovirus species A (Ad12) or adenovirus species C (AdS) El regions, as well as looking at the mechanisms of how a cancer cell could become resistant to NK cell-mediated killing.
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Lehane, Margaret. "Radiation quality as a determinant of transformed cell phenotypes." Thesis, University of St Andrews, 1997. http://hdl.handle.net/10023/14085.

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Transformation is a complex multistage process in vitro by which benign cells gradually acquire characteristics of tumour cells. Transformed C3H10T1/2 cells appear in vitro as multilayers of cells termed foci. Two main aspects of transformation of C3H10T1/2 cells in vitro have been investigated. Firstly, the quantitative assessment of the dose and dose-rate effects after irradiation with 250 kVp X-rays were examined and secondly the relationship between various properties of transformed cells in vitro and their tumourigenic potential in vivo. The induction of transformation was found to be linear with dose for 0.25 to 5 Gy X-rays. Lowering the rate at which the X-ray dose is delivered to the C3H10T1/2 cells lowers the observed transformation frequency by at least a factor of two. A variety of transformed phenotypes are observed in vitro and samples of these phenotypes were developed as cell lines and assessed for a number of properties. These properties were the ability to induce tumours in C3H mice and the ability to reconstruct foci in vitro. Other properties examined were growth in vitro parameters (lag time, doubling time and saturation density) as well as chromosome number and distribution. Tumour cell lines were also developed and assessed for the above properties. Transformation phenotypes induced by X-rays and alpha-particles were compared. Differences were found between some of the properties of the X-ray and alpha- particle induced transformants. In particular, higher proportions of X-ray induced transformants were tumourigenic while most of the alpha-particle induced transformants were non-tumourigenic and also tumours induced by the X-ray induced transformants appeared earlier and grew faster than the alpha-particle induced equivalent. The ability of the transformation phenotypes to reconstruct foci in vitro was greater for alpha-particle induced transformants (not including tumour cell lines) than for the X-ray induced transformants. The reverse was true for tumour cells where X-rays produced higher frequencies of reconstructed foci than alpha-particles. No differences were noted in in vitro growth parameters irrespective of transformation phenotype or radiation type apart from differences in saturation density where the transformation phenotypes (not including tumour cells) generally produced higher densities than the tumour cells for both X-rays and alpha-particles. Chromosome numbers in cells of the different transformation phenotypes (including tumour cells) induced by both X-rays and alpha-particles showed a greater spread and a general shift of the mean and modal chromosome number to lower values than that of untransformed C3H10T1/2 cells. The presence of metacentric chromosomes (Robertsonian chromosomes) was not unique to the radiation induced transformation phenotypes as most of the cell lines examined showed fewer of these chromosomes than the untransformed cells. The X-ray induced transformants (including tumour cells) generally produced more Robertsonian chromosomes than the alpha-particle equivalent. Correlation tests of the above properties with tumourigenicity of the transformed cells revealed a positive correlation of tumourigenicity with the ability to reconstruct foci. A negative correlation was noted between the ability to reconstruct foci and the mean and modal chromosome numbers.
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Abraham, Samuel D. M. "Activation of multiple hemopoietic growth factor genes in Abelson virus transformed myeloid cells." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27786.

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The stringent requirement for hemopoietic growth factors (HGF) in the induction of hemopoiesis in vitro has raised questions as to their possible role(s) in leukemogenesis. Several recent clinical studies have shown aberrant cell growth factor gene activation in patient derived leukemic cells. Assessment of growth factor activity is often based on in vitro bioactivity assays of conditioned media or body fluids. The specificity of this type of endpoint is, however, open to question due to the overlap in biological activities of many HGFs. In assessing the role of growth factor gene expression in a murine myeloid leukemia model I have used a sensitive RNA detection procedure coupled with a vector-probe system that enables the synthesis of uniformly labelled radioactive DNA probes to detect unambiguously the expression of particular growth factor genes. The Abelson murine leukemia virus (A-MuLV) derived myeloid transformants used in this study had previously been shown to produce a multi-lineage colony stimulating activity (CSA). While these A-MuLV transformants were shown to produce GM-CSF, it seemed likely that the multi-lineage CSA was due to another factor. In addition to confirming the expression of GM-CSF mRNA, I was able to show that the cells of all four A-MuLV transformed lines tested also expressed interleukin-3 mRNA. This finding was strongly corroborated by bio-activity data obtained using the CM from the A-MuLV myeloid transformants. Additional preliminary analysis by bioactivity assays have also shown the possible presence of interleukin-6 (IL-6) and a recently described pre-B cell factor suggesting perhaps a common mechanism underlying the activation of these various growth factor genes.
Medicine, Faculty of
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Foulkes, Iain W. "The role of cell-to-cell interactions in the suppression of the transformed phenotype." Thesis, University of Glasgow, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360329.

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De, Haan Judy Bettina. "DNA synthesis and methylation in normal and transformed cells." Master's thesis, University of Cape Town, 1985. http://hdl.handle.net/11427/27266.

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In this study, DNA methylation was examined during the eukaryotic cell cycle, and shown to occur throughout the S phase as well as during the "early" G₂ phase. However, DNA synthesis and methylation of newly synthesized DNA did not occur simultaneously, but the latter lagged behind DNA synthesis by about two hours. Once added during the S phase, the methyl groups were stably maintained in the DNA. Various compounds which are known to affect DNA synthesis in tissue cultured cells, were tested for their ability to alter the methylation status of DNA. The effects of three DNA synthesis inhibitors, viz. hydroxyurea (HU), 1-S-D-arabinofuranosyl cytosine (ara-C) and aphidicolin were examined on a normal embryonic lung fibroblast cell line (WI-38) and its two transformed counterparts, a simian virus 40 (SV 40) transformed line (SVWI-38) and a y-irradiation transformed cell line (CT-1). HU was shown to enhance hypermethylation of pre-existing DNA strands in the normal cells, while ara-C and aphidicolin caused hypermethylation of newly synthesized DNA strands. The effects of various concentrations of a known inducer of gene expression, sodium butyrate, were examined on these three cell lines as well. During a 16-20 hour treatment period, at butyrate concentrations of between 5 and 20 mM, no adverse effect on cell morphology was observed. Cell growth, in the presence of butyrate for 14 hours, showed that butyrate was more toxic on the transformed cells than on the normal cells. However, at 5 mM butyrate, DNA synthesis was inhibited by 75% in the normal cells, and was unaffected in the transformed lines. RNA synthesis was not affected in the transformed cells, whilst in the normal cell line, RNA synthesis was decreased to 76% of the control value, at sodium butyrate concentrations as low as 5 mM. Protein synthesis also was unaffected in the transformed cells and only slightly (+ 10%) inhibited in the normal cells at 20 mM butyrate. SDS polyacrylamide gel electrophoresis of proteins synthesized in the presence of 10 mM sodium butyrate, showed that most proteins were unaffected. Two high molecular weight proteins in the WI-38 cells appeared to be modified during butyrate. treatment, while one protein was induced by butyrate treatment in the CT-1 cells. More importantly though, butyrate treatment also resulted in hypermethylation of DNA, as shown by MSP 1 and Hpa II restriction endonuclease digestion and high-pressure liquid chromatography analysis. Butyrate appeared to specifically cause hypermethylation of pre-existing DNA strands in the WI-38 cells, while the SVWI-38 and CT-1 cells showed preferential hypermethylation of newly synthesized DNA strands. However, the hyper-methylated state was only heritable if the methylation event occurred in newly synthesized DNA. Hypermethylation on pre-existing DNA was rapidly lost in the subsequent generation. It would therefore appear that methylcytosines are only maintained in the DNA if they are generated on newly synthesized DNA. This study has clearly shown that the heritability of DNA methylation patterns is closely linked to DNA replication.
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Saunders, Margaret. "Analysis of immune responses to transformed cells in vitro." Thesis, University of Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.481435.

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Shanmugam, Vijayalakshmi. "Characterization of osteopontin in RSV transformed rat-1 cells and its role in cell transformation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0005/NQ37025.pdf.

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Bove, A. "Single cell approaches to study the interaction between normal and transformed cells in epithelial monolayers." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10049549/.

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Cell competition is a quality control mechanism through which tissues eliminate unfit cells. Cell competition can result from short-range biochemical signals or long-range mechanical cues. However, little is known about how cell-scale interactions give rise to population shifts in tissues, due to the lack of experimental and computational tools to efficiently characterise interactions at the single-cell level. In the work presented in this thesis, I address these challenges by combining long-term automated microscopy with deep learning image analysis to decipher how single-cell behaviour determines tissue make-up during competition. Using a novel high-throughput analysis pipeline, I show that competitive interactions between MDCK wild-type cells and cells depleted of the polarity protein scribble are governed by differential sensitivity to local density and the cell-type of each cell’s neighbours. I find that local density has a dramatic effect on the rate of division and apoptosis under competitive conditions. Strikingly, such analysis reveals that proliferation of the winner cells is up-regulated in neighbourhoods mostly populated by loser cells. These data suggest that tissue-scale population shifts are strongly affected by cellular-scale tissue organisation. I present a quantitative mathematical model that demonstrates the effect of neighbour cell-type dependence of apoptosis and division in determining the fitness of competing cell lines.
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Keith, Michelle Barbara Ann. "Screening of stably transformed insect cell lines for recombinant protein production." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ38634.pdf.

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Books on the topic "Transformed cell"

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Greene, Mark I., and Toshiyuki Hamaoka, eds. Development and Recognition of the Transformed Cell. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1925-2.

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service), SpringerLink (Online, ed. Adhesive Interactions in Normal and Transformed Cells. Totowa, NJ: Springer Science+Business Media, LLC, 2011.

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1947-, Barry John M., ed. The transformed cell: Unlocking the mysteries of cancer. New York: Putnam, 1992.

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Michael, Barry John, ed. The transformed cell: Unlocking the mysteries of cancer. London: Chapmans Publishers, 1992.

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Rosenberg, Steven A. The transformed cell: Unlocking the mysteries of cancer. New York: Avon, 1993.

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1947-, Barry John M., ed. The transformed cell: Unlocking the mysteries of cancer. London: Phoenix, 1993.

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The Nokia revolution: The story of an extraordinary company that transformed an industry. New York: AMACOM, 2001.

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Britton, Fiona Catherine. The molecular and biochemical characterisation of thymidine kinase 1 from normal and transformed mammary cell lines. [S.l: The Author, 1997.

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Rovensky, Yury A. Adhesive Interactions in Normal and Transformed Cells. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-304-2.

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European, Symposium on Calcium Binding Proteins in Normal and Transformed Cells (1st 1989 Brussels Belgium). Calcium binding proteins in normal and transformed cells. New York: Plenum Press, 1990.

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Book chapters on the topic "Transformed cell"

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Rovensky, Yury A. "Cell Migration." In Adhesive Interactions in Normal and Transformed Cells, 121–44. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-304-2_6.

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Rovensky, Yury A. "Topographic Cell Responses." In Adhesive Interactions in Normal and Transformed Cells, 153–84. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-304-2_8.

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Garrels, James I., and B. Robert Franza. "Construction of Protein Databases for Comparison of Normal and Transformed Cells." In Cell Transformation, 209–22. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-5009-5_13.

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Hamaoka, Toshiyuki, Yasuyuki Takai, Atsushi Kosugi, Junko Shima, Takashi Suda, Yumiko Mizushima, Soichiro Sato, and Hiromi Fujiwara. "Application of T Cell—T Cell Interaction to Enhanced Tumor-Specific Immunity Capable of Eradicating Tumor Cells in Vivo." In Development and Recognition of the Transformed Cell, 355–72. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1925-2_22.

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Sager, Georg, Berit E. Bang, Mona Pedersen, and Jarle Aarbakke. "Beta-Adrenergic Receptors of Normal, Transformed and Immature Human Leucocytes." In Tumor Cell Differentiation, 115–20. Totowa, NJ: Humana Press, 1987. http://dx.doi.org/10.1007/978-1-4612-4594-0_8.

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Kumagai, Katsuo, Ryuji Suzuki, Satsuki Suzuki, Tetsu Takahashi, and Minoru Igarashi. "A Regulatory Role of Natural Killer Cells (LGL) in T-Cell-Mediated Immune Response." In Development and Recognition of the Transformed Cell, 261–77. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1925-2_17.

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Cheresh, David A. "Ganglioside Involvement in Tumor Cell—Substratum Interactions." In Development and Recognition of the Transformed Cell, 407–28. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1925-2_25.

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Marchev, Andrey S., Zhenya P. Yordanova, and Milen I. Georgiev. "Transformed Root Culture: From Genetic Transformation to NMR-Based Metabolomics." In Plant Cell Culture Protocols, 457–74. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8594-4_32.

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Al, E. J. M., R. A. Mijnhart, N. J. J. Dekker, R. J. P. Ouwerkerk, H. M. G. Sillekens, and P. C. van Mourik. "Optimization of Human Antibody Production by Xenohybridization of EBV-Transformed Cell Lines." In Animal Cell Technology, 801–6. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-011-5404-8_128.

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Comoglio, P. M., D. Cirillo, M. F. Di Renzo, R. Ferracini, F. G. Giancotti, S. Giordano, L. Naldini, G. Tarone, and P. C. Marchisio. "Identification and Localization of Phosphoproteins in v-onc Transformed Fibroblasts by Means of Phosphotyrosine Antibodies." In Cell Transformation, 97–112. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-5009-5_5.

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Conference papers on the topic "Transformed cell"

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Teo, Soo Kng, Kim Parker, and K. H. Chiam. "Viscoelastic Finite-Element Modelling of Cell Deformation in an Optical Stretcher." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176085.

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In this paper, we discuss the results arising from using a finite-element model [1] of cell deformation to study the optical stretching [2,3] of normal and malignantly transformed fibroblast cells. The key feature of our model is the use of a constitutive viscoelastic fluid element [4] whose parameters are both spatially and temporally varying so as to mimic the experimentally-observed spatiotemporal heterogeneity of cellular material properties. First, we show that normal fibroblast cells can undergo active cellular response by increasing their cellular viscosity when optically stretched for loading times of between 0.2s and 2.5s. Second, we show that, under similar optical conditions, cells of a smaller radius will experience more stretching compared to cells of a larger radius. This may explain why malignantly transformed cells experience higher strains than normal cells. Third, we compute the extent of the propagation of stress in the cytoplasm, and show that, for malignantly transformed cells, the maximal stress does propagate into the nuclear region whereas for normal cells, the maximal stress does not. We discuss how this may impact the transduction of cancer signalling pathways.
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Michaelson, Jarett, Heejin Choi, Peter So, and Hayden Huang. "Mechanical Properties of Primary and Immortal Fibroblasts in Cell Bi-Layers." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80385.

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Immortalized cells are commonly used as analogs for primary cells in many cell mechanics, tissue engineering, and biochemical assays. However, it is not well-established whether immortal cell lines can mimic the behavior of primary cells in more physiological (three-dimensional) environments. For this project, we investigate the mechanical properties of primary cardiac fibroblasts (CFs) and 3T3 transformed fibroblasts when cultured in cell bi-layers by comparing the cells’ viscoelastic properties.
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Ma, Kaixue, Shouxian Mou, Keping Wang, Nagarajan Mahalingam, and Kiat Seng Yeo. "Transformed radial stub cell embedded resonator for high performance filter applications." In 2012 IEEE/MTT-S International Microwave Symposium - MTT 2012. IEEE, 2012. http://dx.doi.org/10.1109/mwsym.2012.6258258.

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Salmanzadeh, Alireza, Harsha Kittur, Michael B. Sano, Mark A. Stremler, P. Christopher Roberts, Eva M. Schmelz, and Rafael V. Davalos. "Investigating Dielectrophoretic Signature of Mouse Ovarian Surface Epithelial Cells, Macrophages and Fibroblasts." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80872.

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Epithelial ovarian carcinomas are the fourth leading cause of death in women in the United States among all cancers and the leading cause of death from gynecological malignancies1. The main reason for this high rate of mortality is the inability to properly detect these carcinomas early. Investigations for diagnosing ovarian cancer in early stages have been hindered by two major obstacles: lack of adequate cell models to study different cancer stages and lack of a reliable technique to isolate these cancer cells from peritoneal fluid. In trying to solve the first challenge, Dr. Schmelz and collaborators presented a transformed mouse ovarian surface epithelial (MOSE) cell model by isolating different transitional stages of ovarian cancer as cells progressed from a premalignant nontumorigenic phenotype to a highly aggressive malignant phenotype2, 3. In this model four stages of transformed cells, namely early (MOSE-E), early-intermediate (MOSE-E/I), intermediate (MOSE-I) and late (MOSE-L) cells, were distinguishable3. In the current study, we attempt to solve the second challenge of isolating cancer cells from macrophages and fibroblasts, which are found in the peritoneal fluid. Based on differences in cells’ intrinsic electrical properties, a new cell manipulation technique, contactless dielectrophoresis (cDEP), was implemented.
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Nerurkar, Nandan L., and Clifford J. Tabin. "Cell Velocity Gradients Underlie Early Morphogenesis of the Avian Gut Tube." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80898.

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At the end of gastrulation, the endoderm forms the ventral surface of the developing embryo. Subsequently, through a series of poorly understood morphogenetic events, the initially flat endoderm is transformed into the gut tube, a cylindrical structure that gives rise to the epithelial lining of the entire respiratory and gastrointestinal tracts. At present there is no mechanistic understanding of how the endoderm is transformed from a planar sheet to a simple tube. In avian and mammalian species, formation of the gut tube begins with two invaginations at the anterior and posterior poles of the embryo, termed the anterior (AIP) and caudal intestinal portals (CIP). The AIP, which forms the foregut, and CIP which forms the hindgut, begin moving toward one another, “zipping” the gut tube closed along the embryonic midline (Fig. 1A). The AIP and CIP meet at the umbilicus (mammals) or yolk stalk (avian), where the midgut is formed.
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Lalli, Mark L., and Anand R. Asthagiri. "Investigating electrotaxis of the non-transformed MCF-10A mammary epithelial cell line." In 2014 40th Annual Northeast Bioengineering Conference (NEBEC). IEEE, 2014. http://dx.doi.org/10.1109/nebec.2014.6972848.

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Kuanquan Wang, Dong Sui, Wei Wang, Yongfeng Yuan, and Wangmeng Zuo. "A cell counting method for BEVS based on nonlinear Transformed Sliding Band Filter." In 2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2012. http://dx.doi.org/10.1109/embc.2012.6345885.

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Su, H., T. Xu, S. Ganapathy, and Z.-M. Yuan. "P2-02-04: Novel Functions of vps34 in Non-Transformed Epithelial Cells: Regulation of Cell Proliferation and Tumorigenesis." In Abstracts: Thirty-Fourth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 6‐10, 2011; San Antonio, TX. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/0008-5472.sabcs11-p2-02-04.

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Lai, Junyun, Wei Jian Tan, Chien Tei Too, Nalini Srinivasan, Lan Hiong Wong, Fatimah Mustafa, Soh Ha Chan, Jianzhu Chen, and Paul Anthony MacAry. "Abstract B095: Targeting Epstein-Barr virus transformed B lymphoblastoid cells using antibodies with T cell receptor-like specificities." In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-b095.

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Sepe, Leandra, Concita Cantarella, Francesca Fioretti, and Giovanni Paolella. "Quantitative in vitro characterization of transformed cell lines as a model for metastatic dissemination." In 2009 IEEE International Workshop on Medical Measurements and Applications (MeMeA). IEEE, 2009. http://dx.doi.org/10.1109/memea.2009.5167991.

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Reports on the topic "Transformed cell"

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Ince, Tan A. Epigenetic Regulation of Normal and Transformed Breast Epithelial Cell Phenotype. Fort Belvoir, VA: Defense Technical Information Center, June 2009. http://dx.doi.org/10.21236/ada514040.

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Norman Bessette, Douglas S. Schmidt, Jolyon Rawson, Rhys Foster, and Anthony Litka. Fuel Transformer Solid Oxide Fuel Cell. Office of Scientific and Technical Information (OSTI), January 2007. http://dx.doi.org/10.2172/909613.

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Norman Bessette, Douglas S. Schmidt, Jolyon Rawson, Rhys Foster, and Anthony Litka. Fuel Transformer Solid Oxide Fuel Cell. Office of Scientific and Technical Information (OSTI), July 2006. http://dx.doi.org/10.2172/898110.

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Norman Bessette, Douglas S. Schmidt, Jolyon Rawson, Lars Allfather, and Anthony Litka. FUEL TRANSFORMER SOLID OXIDE FUEL CELL. Office of Scientific and Technical Information (OSTI), March 2005. http://dx.doi.org/10.2172/840679.

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Norman Bessette, Douglas S. Schmidt, Jolyon Rawson, Lars Allfather, and Anthony Litka. Fuel Transformer Solid Oxide Fuel Cell. Office of Scientific and Technical Information (OSTI), August 2005. http://dx.doi.org/10.2172/859103.

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Conrad, Samuel E. Regulation of the Gl-S-Phase Transition in Non-Transformed and Transformed Human Breast Epithelial Cells. Fort Belvoir, VA: Defense Technical Information Center, October 1995. http://dx.doi.org/10.21236/ada303143.

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Norman Bessette, Douglas S. Schmidt, Jolyon Rawson, Rhys Foster, and Anthony Litka. Program Area of Interest: Fuel Transformer Solid Oxide Fuel Cell. Office of Scientific and Technical Information (OSTI), February 2006. http://dx.doi.org/10.2172/886019.

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Dyakova, Lora, Tanya Zhivkova, Rossen Spasov, Reni Kalfin, and Radostina Alexandrova. Disulfiram as a New Potential Anticancer Agent – Influence on Viability and Proliferation of Virus-transformed Tumour Cells. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, December 2019. http://dx.doi.org/10.7546/crabs.2019.11.14.

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Wilcoski, James, and Steven J. Smith. Fragility Testing of a Power Transformer Bushing; Demonstration of CERL Equipment Fragility and Protection Procedure. Fort Belvoir, VA: Defense Technical Information Center, February 1997. http://dx.doi.org/10.21236/ada341297.

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Villa, E. Analysis of F-Canyon Effluents During the Dissolution Cycle with a Fourier Transform Infrared Spectrometer/Multipath Cell. Office of Scientific and Technical Information (OSTI), July 1999. http://dx.doi.org/10.2172/9297.

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