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Relevant bibliographies by topics / Translational large animal model

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Academic literature on the topic 'Translational large animal model'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Translational large animal model"

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Qi, Steven S., Laura Hocum Stone, Cory Swingen, Christin Wright, and Rosemary F. Kelly. "Diastolic Dysfunction in a Translational Large Animal Model." Journal of the American College of Surgeons 231, no. 4 (2020): S46—S47. http://dx.doi.org/10.1016/j.jamcollsurg.2020.07.071.

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Eaton, Samantha L., Fraser Murdoch, Nina M. Rzechorzek, et al. "Modelling Neurological Diseases in Large Animals: Criteria for Model Selection and Clinical Assessment." Cells 11, no. 17 (2022): 2641. http://dx.doi.org/10.3390/cells11172641.

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Issue: The impact of neurological disorders is recognised globally, with one in six people affected in their lifetime and few treatments to slow or halt disease progression. This is due in part to the increasing ageing population, and is confounded by the high failure rate of translation from rodent-derived therapeutics to clinically effective human neurological interventions. Improved translation is demonstrated using higher order mammals with more complex/comparable neuroanatomy. These animals effectually span this translational disparity and increase confidence in factors including routes o

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Obeid, Michele, Ramzy C. Khabbaz, Kelly D. Garcia, Kyle M. Schachtschneider, and Ron C. Gaba. "Translational Animal Models for Liver Cancer." American Journal of Interventional Radiology 2 (February 24, 2018): 2. http://dx.doi.org/10.25259/ajir-11-2017.

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Animal models have become increasingly important in the study of hepatocellular carcinoma (HCC), as they serve as a critical bridge between laboratory-based discoveries and human clinical trials. Developing an ideal animal model for translational use is challenging, as the perfect model must be able to reproduce human disease genetically, anatomically, physiologically, and pathologically. This brief review provides an overview of the animal models currently available for translational liver cancer research, including rodent, rabbit, non-human primate, and pig models, with a focus on their resp

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Vilahur, Gemma, Teresa Padro, and Lina Badimon. "Atherosclerosis and Thrombosis: Insights from Large Animal Models." Journal of Biomedicine and Biotechnology 2011 (2011): 1–12. http://dx.doi.org/10.1155/2011/907575.

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Atherosclerosis and its thrombotic complications are responsible for remarkably high numbers of deaths. The combination ofin vitro, ex vivo, andin vivoexperimental approaches has largely contributed to a better understanding of the mechanisms underlying the atherothrombotic process. Indeed, different animal models have been implemented in atherosclerosis and thrombosis research in order to provide new insights into the mechanisms that have already been outlined in isolated cells and protein studies. Yet, although no model completely mimics the human pathology, large animal models have demonstr

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Kőrösi, Dénes, András Vorobcsuk, Dániel Fajtai, Ottó Tátrai, Emőke Bodor, and Rita Garamvölgyi. "Closed-chest occlusion of the left anterior descending artery in swine infarction model." Acta Agraria Kaposváriensis 27, no. 1-2 (2023): 77–85. http://dx.doi.org/10.31914/aak.3423.

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Pigs have played a significant role in biological and medical research for many years. In the case of non-rodent models, pigs are the primary choices as experimental animals in the cardiovascular studies. Accumulating data indicate that the closed-chest coronary balloon-occlusion technique is one of the most successful method for creating ischemic heart failure (HF). However, consistent and thoroughly characterized large animal models of HF are a critical translational tool for drug development and toxicology. The knowledge of the different catheterization protocols is crucial to ensure a suit

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Hollister, S. J., M. B. Wheeler, S. E. Feinberg, and W. L. Murphy. "THE IMPORTANCE OF LARGE ANIMAL MODELS FOR TRANSLATIONAL RESEARCH IN BONE TISSUE ENGINEERING." Reproduction, Fertility and Development 24, no. 1 (2012): 287. http://dx.doi.org/10.1071/rdv24n1ab249.

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The translation of bone tissue engineering (BTE) research to clinical use has been absymal1. Outside of bone void filler biomaterials, only Bone Morphogenetic Protein 2 (BMP2) has made significant inroads to clinical practice, and even BMP2 use has been associated with significant complications including death, dysphagia, and ectopic bone formation. The dearth of BTE products can be attributed to two main causes: (1) the need to develop BTE systems, that successfully integrate scaffolds, growth factors like BMP2 and cells and (2) the need to adapt and implement such systems for a wide variety

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Taha, Aladdin, Joaquim Bobi, Ruben Dammers, et al. "Comparison of Large Animal Models for Acute Ischemic Stroke: Which Model to Use?" Stroke 53, no. 4 (2022): 1411–22. http://dx.doi.org/10.1161/strokeaha.121.036050.

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Translation of acute ischemic stroke research to the clinical setting remains limited over the last few decades with only one drug, recombinant tissue-type plasminogen activator, successfully completing the path from experimental study to clinical practice. To improve the selection of experimental treatments before testing in clinical studies, the use of large gyrencephalic animal models of acute ischemic stroke has been recommended. Currently, these models include, among others, dogs, swine, sheep, and nonhuman primates that closely emulate aspects of the human setting of brain ischemia and r

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Sorby-Adams, Annabel J., Robert Vink, and Renée J. Turner. "Large animal models of stroke and traumatic brain injury as translational tools." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 315, no. 2 (2018): R165—R190. http://dx.doi.org/10.1152/ajpregu.00163.2017.

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Acute central nervous system injury, encompassing traumatic brain injury (TBI) and stroke, accounts for a significant burden of morbidity and mortality worldwide. Studies in animal models have greatly enhanced our understanding of the complex pathophysiology that underlies TBI and stroke and enabled the preclinical screening of over 1,000 novel therapeutic agents. Despite this, the translation of novel therapeutics from experimental models to clinical therapies has been extremely poor. One potential explanation for this poor clinical translation is the choice of experimental model, given that

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Walker, Rebecca L., and Matthias Eggel. "From Mice to Monkeys? Beyond Orthodox Approaches to the Ethics of Animal Model Choice." Animals 10, no. 1 (2020): 77. http://dx.doi.org/10.3390/ani10010077.

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Recent developments in genome editing tools, along with limits in the translational potential of rodent models of human disease, have spurred renewed biomedical research interest in large mammals like nonhuman primates, pigs, and dogs. Such scientific developments raise ethical issues about the use of these animals in comparison with smaller mammals, such as mice and rats. To examine these ethical questions, we first consider standard (or “orthodox”) approaches, including ethics oversight within biomedical research communities, and critical theoretical reflections on animal research, including

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Krause, S., S. Reichert, T. Donandt, et al. "Molecular therapy in a novel translational large animal model for Duchenne muscular dystrophy." Neuromuscular Disorders 27 (October 2017): S188—S189. http://dx.doi.org/10.1016/j.nmd.2017.06.345.

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Dissertations / Theses on the topic "Translational large animal model"

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Monreal, Gretel. "Ventricular Remodeling in a Large Animal Model of Heart Failure." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1210007937.

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Steele, Allison M. "NEW INSIGHTS INTO POST-SEPSIS MUSCLE WEAKNESS ELUCIDATED USING A NOVEL ANIMAL MODEL." UKnowledge, 2017. https://uknowledge.uky.edu/physiology_etds/37.

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Sepsis is a severe life-threatening critical illness that damages multiple physiological systems. After hospital discharge, more than 70% of severe sepsis survivors report profound weakness which significantly impacts quality of life. Such weakness gives rise to new limitations of daily living, which ultimately leads to loss of independence in many patients. Despite wide recognition of this serious issue by clinicians and researchers alike, the mechanisms contributing to chronic skeletal muscle dysfunction after sepsis are not well understood. Lack of progress in this field is largely due to t

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Cove-Smith, Laura Suzanne. "Cardiotoxicity from cancer therapy : a translational approach to biomarker development." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/cardiotoxicity-from-cancer-therapy-a-translational-approach-to-biomarker-development(b9cc1130-250e-4d75-84b5-bebe8148c26d).html.

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Background: Heart damage from cancer therapy is a significant problem for survivors. Some of the most effective treatments, such as anthracyclines, cause heart toxicity that can lead to significant morbidity and mortality. Cardiotoxicity also contributes to the loss of promising cancer drugs in early development and is notoriously difficult to predict. This translational project employs parallel pre-clinical and clinical studies to explore circulating biomarkers and cardiac magnetic resonance imaging (CMR) during development of anthracycline associated cardiotoxicity with the aim of finding bi

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Green, Andrea Michelle. "Visual-vestibular interaction in a bilateral model of the rotational and translational vestibulo-ocular reflexes : an investigation of viewing-context-dependent reflex performance." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=36810.

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Traditionally, the vestibulo-ocular reflex (VOR) has been considered a stereotyped ocular counterrotation response to head movement that stabilizes a visual image on the retinae. However, during natural head movements, the appropriate magnitudes and directions of compensatory ocular deviations depend on viewing context. Moment-to-moment adjustments in VOR performance are required as gaze is redirected towards different viewing locations.<br>This thesis presents an investigation of viewing-context-dependent VOR performance through the development of a physiologically and anatomically based bila

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Hettiaratchy, Shehan Peter. "The use of mixed haematopoietic chimerism to generate allograft tolerance in a large animal model." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433322.

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Hossain, Mohammad Ayaz. "Candidate biomarkers of renal warm ischaemia in a donation after circulatory death large animal model." Thesis, St George's, University of London, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686431.

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Background The increased use of donation after circulatory death (DCD) kidneys in the UK has followed a UK government mandate of a 50% increase in organ donation from 2008- 2013. DCD kidneys have associated higher rates of delayed graft function (DGF) and primary non-function (PNF), which is thought to be due to warm ischaemia (WI) exposure during the retrieval process. This project aimed to utilise a porcine model of DCD WI in order to examine candidate biomarkers. Both a proteomic (2D DIGE) and a genomic (expression microarray) study were undertaken with appropriate validation. Methods Sched

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Reichert, Johannes Christian. "Tissue engineering bone - reconstruction of critical sized segmental bone defects in a large animal model." Thesis, Queensland University of Technology, 2010. https://eprints.qut.edu.au/48080/1/Johannes_Reichert_Thesis.pdf.

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Currently, well established clinical therapeutic approaches for bone reconstruction are restricted to the transplantation of autografts and allografts, and the implantation of metal devices or ceramic-based implants to assist bone regeneration. Bone grafts possess osteoconductive and osteoinductive properties, their application, however, is associated with disadvantages. These include limited access and availability, donor site morbidity and haemorrhage, increased risk of infection, and insufficient transplant integration. As a result, recent research focuses on the development of complementar

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Kyeremanteng, Catherine. "The Biological and Behavioural Effects of Electroconvulsive Stimulus in Rodents: Investigation and Translational Implications of a Genetic Animal Model of Depression." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/20694.

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Electroconvulsive therapy (ECT) is one of the oldest and most effective treatments for depression; however, its biological underpinnings are poorly understood. Brain-derived neurotrophic factor (BDNF) and the hypothalamic-pituitary-adrenal (HPA) axis are two chemical messenger systems implicated in the antidepressant action and cognitive side effects of ECT. The Wistar-Kyoto (WKY) strain is a genetic model of depression that shows biological, cognitive, behavioural, and treatment-response abnormalities, making it potentially a useful model in which to investigate the underpinnings of the actio

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Tran, Nam D. "In utero gene transfer into fetal sheep : a large animal model for in utero gene therapy /." abstract and full text PDF (UNR users only), 1999. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:9961136.

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de, Strobel Francesca. "IN VIVO CHARACTERIZATION OF A NEW TRANSPEDICULAR APPROACH TO THE INTERVERTEBRAL DISC IN A LARGE ANIMAL MODEL." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3424387.

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Back pain (BP) is a common clinical condition that leads to high morbidity with significant psychosocial and economic effects. It is the leading cause of disability in people under 45 years of age, and it results in enormous national economic losses in developed countries. The wide majority of BP is associated with degenerative changes of the intervertebral disc (IVD).  Intervertebral disc degeneration (IVDD) is an age-related chronic process that is characterized by a progressive reduction of proteoglycans and water content in the nucleus pulposus (NP) with loss of the IVD's ability to resist

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Books on the topic "Translational large animal model"

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Lewis, Carroll. Ailisi jing zhong yu ji: Through the looking-glass. Jiu yi chu ban she, 1999.

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Lewis, Carroll. Ailisi jing zhong qi yu. Guo ji shao nian cun, 1996.

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Karpova, Nina N. Pharmacological Adjuncts and Evidence-Supported Treatments for Trauma. Edited by Sara Maltzman. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199739134.013.32.

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A large proportion of humans experienced a traumatic event in their lifetime, with more than 10% developing posttraumatic stress disorder (PTSD), panic disorder, phobias, and other fear/anxiety disorders. The neural circuitry of fear responses is highly conserved in humans as well as rodents, and this allows for translational research using animal models of fear. Fear/anxiety disorders in humans are most efficiently treated by exposure-based psychotherapy (i.e., cognitive behavioral therapy; CBT), the main aspects of which are closely modeled by extinction training in Pavlovian fear conditioni

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Striedter, Georg. Model Systems in Biology. The MIT Press, 2022. http://dx.doi.org/10.7551/mitpress/14366.001.0001.

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How biomedical research using various animal species and in vitro cellular systems has resulted in both major successes and translational failure. In Model Systems in Biology, comparative neurobiologist Georg Striedter examines how biomedical researchers have used animal species and in vitro cellular systems to understand and develop treatments for human diseases ranging from cancer and polio to Alzheimer's disease and schizophrenia. Although there have been some major successes, much of this “translational” research on model systems has failed to generalize to humans. Striedter explores the h

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Morinobu, Shigeru, Shigeto Yamamoto, and Manabu Fuchikami. Translational Research from Animals to Humans. Edited by Israel Liberzon and Kerry J. Ressler. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190215422.003.0017.

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To elucidate the pathophysiology of post-traumatic stress disorder (PTSD), the establishment of an appropriate animal model is necessary. In a series of studies, the authors validated single prolonged stress (SPS) as a model for PTSD. SPS-treated rats mimic the pathophysiological abnormalities and behavioral characteristics of PTSD, such as enhanced anxiety-like behavior, glucocorticoid negative feedback, and analgesia. In addition, the authors demonstrated enhanced freezing in response to contextual fear conditioning, and impaired extinction of fear memory, which was alleviated by D-cycloseri

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Baglietto-Vargas, David, Rahasson R. Ager, Rodrigo Medeiros, and Frank M. LaFerla. Animal Models of Neurodegenerative Diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0014.

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The incidence and prevalence of neurodegenerative disorders (e.g., Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD), etc.) are growing rapidly due to increasing life expectancy. Researchers over the past two decades have focused their efforts on the development of animal models to dissect the molecular mechanisms underlying neurodegenerative disorders. Existing models, however, do not fully replicate the symptomatic and pathological features of human diseases. This chapter focuses on animal models of AD, as this disorder is the most prevalent of the brain degen

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Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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Lewis, Carroll. Through the Looking-Glass Large Print. Independently Published, 2019.

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Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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Book chapters on the topic "Translational large animal model"

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Uthamanthil, Rajesh K., and Mei Tian. "ROLE OF LARGE ANIMAL MODELS IN TRANSLATIONAL STUDIES OF IMAGING AND TARGETED DRUG DELIVERY." In Drug Delivery Applications of Noninvasive Imaging. John Wiley & Sons, Inc, 2013. http://dx.doi.org/10.1002/9781118356845.ch17.

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Njenga, M. K., A. Matsumori, and J. K. Gwathmey. "Large Animal Model of Viral Myocarditis." In Developments in Cardiovascular Medicine. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-9264-2_24.

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Slaughenhoupt, Bruce L., and John P. Gearhart. "A Large Animal Model of Bladder Exstrophy." In The Exstrophy—Epispadias Complex. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4757-3056-2_9.

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Chaudhari, Pradip. "Preclinical Animal Model and Non-invasive Imaging in Apoptosis." In Proteases in Apoptosis: Pathways, Protocols and Translational Advances. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19497-4_6.

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Martins, Raphaël P., and José Jalife. "Generating a Large Animal Model of Persistent Atrial Fibrillation." In Manual of Research Techniques in Cardiovascular Medicine. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118495148.ch3.

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Gavin, P. R., S. L. Kraft, C. E. DeHaan, M. L. Griebenow, and M. P. Moore. "A Large Animal Model for Boron Neutron Capture Therapy." In Progress in Neutron Capture Therapy for Cancer. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3384-9_106.

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Ozturk, Can, Safak Uygur, and Miroslaw Lukaszuk. "Sheep as a Large Animal Model for Nerve Regeneration Studies." In Plastic and Reconstructive Surgery. Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-6335-0_62.

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Gavin, P. R., S. L. Kraft, C. E. DeHaan, R. D. Sande, M. Papageorges, and W. F. Bauer. "Spontaneous Canine Oral Melanoma: A Large Animal Model for BNCT." In Progress in Neutron Capture Therapy for Cancer. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3384-9_91.

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Hilgers, Luuk A. Th. "Large-Animal Model for Establishing E/T Ratio of Adjuvants." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-585-9_17.

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Mo, Weilan, and J. Kevin Donahue. "Atrial Gene Painting in Large Animal Model of Atrial Fibrillation." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2707-5_16.

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Conference papers on the topic "Translational large animal model"

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Kim, Keuntae, and Chung Hyuk Park. "Data-Driven Natural Behavior Model Design with Large Language Models for Robotic-Animal Assisted Interventions (RAAI)." In 2025 20th ACM/IEEE International Conference on Human-Robot Interaction (HRI). IEEE, 2025. https://doi.org/10.1109/hri61500.2025.10973862.

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Rathod, Megh H., Samantha Unger, Heather J. Ross, Leo Shmuylovich, Mitchell Pet, and Daniel Franklin. "Development of a melanin-inclusive reflective pulse oximeter model for equitable performance tested in a large-animal model undergoing hypoxia: pilot study." In Optical Diagnostics and Sensing XXV: Toward Point-of-Care Diagnostics, edited by Justin S. Baba and Gerard L. Coté. SPIE, 2025. https://doi.org/10.1117/12.3042334.

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Aires, Jeremy, Shannah Withrow-Maser, and Nicholas Peters. "Utilizing Advanced Air Mobility Rotorcraft Tools for Wildfire Applications." In Vertical Flight Society 80th Annual Forum & Technology Display. The Vertical Flight Society, 2024. http://dx.doi.org/10.4050/f-0080-2024-1079.

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Over the past decade, due in large part to heavy investment in the field of Advanced Air Mobility (AAM), significant progress in rotorcraft-focused modeling tools has been made. Such progress has notably increased AAM rotorcraft modeling capabilities in the topics of conceptual design, preliminary design, and more recently flight dynamics. Yet, due to recent and persistent increases in extreme weather events, an emerging interest has been raised in utilizing such modeling capabilities for aiding in emergency relief efforts and other public good missions. This paper uses wildfire fighting as a

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Gadomski, B. C., K. C. McGilvray, J. T. Easley, R. H. Palmer, and C. M. Puttlitz. "Simulating Microgravity in a Large Animal Model." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14215.

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The microgravity environment encountered during spaceflight has numerous deleterious effects on the human body, with one of the most drastic being decreased bone mass due to mechanical unloading. These alterations in bone mass and skeletal strength are one of the foremost limitations of future space exploration. Due to the cost of long-duration space missions, it is critically important to develop ground-based models of the microgravity environment encountered during spaceflight to investigate possible countermeasures to maintain skeletal integrity.

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Schröter, L., F. Kaiser, S. Stein, B. T. Krüger, U. Gbureck, and A. Ignatius. "Magnesium phosphate granules support bone regeneration in a large animal model." In III. MuSkITYR Symposium. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736727.

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Krafsur, G. M., K. Jennings, R. D. Brown, et al. "Obesity Modifies Pulmonary Hypertension and Heart Disease in a Large Animal Model." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4200.

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Xin, Y., M. Cereda, H. Hamedani, et al. "Assessing Voxel Recruitment in Prone Ventilation in a Large ARDS Animal Model." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2317.

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Xin, Y., T. Mandelbaum, A. Lenart, et al. "Propagation of Lung Injury in a Large Animal Model of Acid Aspiration." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1154.

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Derseh, H. B., K. U. E. Perera, V. D. S. Nimanthi, et al. "Tetrathiomolybdate Treatment Attenuates Bleomycin-Induced Pulmonary Fibrosis in a Large Animal Model." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2578.

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Balivada, Sivasai, Matthew T. Basel, Marla Pyle, et al. "Abstract LB-116: Immunodeficient pigs as a large animal model for human tumors." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-lb-116.

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Reports on the topic "Translational large animal model"

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McKinley, Todd O. Mitochondrial Based Treatments that Prevent Posttraumatic Osteoarthritis in a Translational Large Animal Intraarticular Fracture Survival Model. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada567276.

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McKinley, Todd O., and James A. Martin. Mitochondrial Based Treatments that Prevent Post-Traumatic Osteoarthritis in a Translational Large Animal Intraarticular Fracture Survival Model. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada592443.

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Gavin, Patrick. BNCT - Large animal model studies utilizing epithermal neutrons. Office of Scientific and Technical Information (OSTI), 1998. http://dx.doi.org/10.2172/761739.

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Goetz, Jessica E. A Clinically Realistic Large Animal Model of Intra-Articular Fracture. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada612770.

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Tochigi, Yuki. A Clinically Realistic Large Animal Model of Intra-Articular Fracture. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada570059.

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Goetz, Jessica E. A Clinically Realistic Large Animal Model of Intra-Articular Fracture. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada591969.

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Wade, Charles E. Characterization and Application of a Large Animal Model of Penetrating Ballistic Brain Injury (PBBI). Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada559331.

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Gallogly, Hilary. Comparative Testing of Hemostatic Dressing in a Large Animal Model (Sus Scorofa) with Severe hepatic Injuries. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada608134.

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Lai, Chin-Ta, and Joel Conte. Dynamic Modeling of the UC San Diego NHERI Six-Degree-of-Freedom Large High-Performance Outdoor Shake Table. Pacific Earthquake Engineering Research Center, University of California, Berkeley, CA, 2024. http://dx.doi.org/10.55461/jsds5228.

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Abstract:

The UC San Diego Large High-Performance Outdoor Shake Table (LHPOST), which was commissioned on October 1, 2004 as a shared-use experimental facility of the National Science Foundation (NSF) Network for Earthquake Engineering Simulation (NEES) program, was upgraded from its original one degree-of-freedom (LHPOST) to a six degree-of-freedom configuration (LHPOST6) between October 2019 and April 2022. The LHPOST6 is a shared-use experimental facility of the NSF Natural Hazard Engineering Research Infrastructure (NHERI) program. A mechanics-based numerical model of the LHPOST6 able to capture the

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Shrestha, Tanuja, Mir A. Matin, Vishwas Chitale, and Samuel Thomas. Exploring the potential of deep learning for classifying camera trap data: A case study from Nepal - working paper. International Centre for Integrated Mountain Development (ICIMOD), 2023. http://dx.doi.org/10.53055/icimod.1016.

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Data from camera trap networks provide crucial information on various important aspects of wildlife presence, movement, and behaviour. However, manual processing of large volumes of images captured is time and resource intensive. This study explores three different approaches of deep learning methods to detect and classify images of key animal species collected from the ICIMOD Knowledge Park at Godavari, Nepal. It shows that transfer learning with ImageNet pretrained models (A1) can be used to detect animal species with minimal model training and testing. These methods when scaled up offer tre

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