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Books on the topic 'Translational large animal model'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Lewis, Carroll. Ailisi jing zhong yu ji: Through the looking-glass. Jiu yi chu ban she, 1999.

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Lewis, Carroll. Ailisi jing zhong qi yu. Guo ji shao nian cun, 1996.

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3

Karpova, Nina N. Pharmacological Adjuncts and Evidence-Supported Treatments for Trauma. Edited by Sara Maltzman. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199739134.013.32.

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A large proportion of humans experienced a traumatic event in their lifetime, with more than 10% developing posttraumatic stress disorder (PTSD), panic disorder, phobias, and other fear/anxiety disorders. The neural circuitry of fear responses is highly conserved in humans as well as rodents, and this allows for translational research using animal models of fear. Fear/anxiety disorders in humans are most efficiently treated by exposure-based psychotherapy (i.e., cognitive behavioral therapy; CBT), the main aspects of which are closely modeled by extinction training in Pavlovian fear conditioni

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4

Striedter, Georg. Model Systems in Biology. The MIT Press, 2022. http://dx.doi.org/10.7551/mitpress/14366.001.0001.

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How biomedical research using various animal species and in vitro cellular systems has resulted in both major successes and translational failure. In Model Systems in Biology, comparative neurobiologist Georg Striedter examines how biomedical researchers have used animal species and in vitro cellular systems to understand and develop treatments for human diseases ranging from cancer and polio to Alzheimer's disease and schizophrenia. Although there have been some major successes, much of this “translational” research on model systems has failed to generalize to humans. Striedter explores the h

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5

Morinobu, Shigeru, Shigeto Yamamoto, and Manabu Fuchikami. Translational Research from Animals to Humans. Edited by Israel Liberzon and Kerry J. Ressler. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190215422.003.0017.

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To elucidate the pathophysiology of post-traumatic stress disorder (PTSD), the establishment of an appropriate animal model is necessary. In a series of studies, the authors validated single prolonged stress (SPS) as a model for PTSD. SPS-treated rats mimic the pathophysiological abnormalities and behavioral characteristics of PTSD, such as enhanced anxiety-like behavior, glucocorticoid negative feedback, and analgesia. In addition, the authors demonstrated enhanced freezing in response to contextual fear conditioning, and impaired extinction of fear memory, which was alleviated by D-cycloseri

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6

Baglietto-Vargas, David, Rahasson R. Ager, Rodrigo Medeiros, and Frank M. LaFerla. Animal Models of Neurodegenerative Diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0014.

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The incidence and prevalence of neurodegenerative disorders (e.g., Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD), etc.) are growing rapidly due to increasing life expectancy. Researchers over the past two decades have focused their efforts on the development of animal models to dissect the molecular mechanisms underlying neurodegenerative disorders. Existing models, however, do not fully replicate the symptomatic and pathological features of human diseases. This chapter focuses on animal models of AD, as this disorder is the most prevalent of the brain degen

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7

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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8

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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9

Lewis, Carroll. Through the Looking-Glass Large Print. Independently Published, 2019.

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10

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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11

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2020.

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12

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2020.

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13

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2019.

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14

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2020.

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15

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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16

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2020.

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17

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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18

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2019.

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19

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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20

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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21

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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22

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2019.

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23

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2020.

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24

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2019.

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25

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2019.

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26

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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27

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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28

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2021.

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29

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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30

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2019.

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31

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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32

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2018.

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33

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2018.

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34

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2019.

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35

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2019.

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36

Lewis, Carroll. Through the Looking Glass: Large Print. Independently Published, 2018.

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37

Through the Looking-Glass: Large Print. Independently Published, 2018.

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38

Lewis, Carroll. Through the Looking-Glass: Large Print. Independently Published, 2020.

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39

Lewis, Carroll. Through the Looking-Glass and What Alice Found There: Large Print. Independently Published, 2019.

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40

Lewis, Carroll. Through the Looking-Glass and What Alice Found There: Large Print. Independently Published, 2019.

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41

Lewis, Carroll. Through the Looking-Glass and What Alice Found There: Large Print. Independently Published, 2019.

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42

Lewis, Carroll. Through the Looking-Glass : And What Alice Found There: Large Print. Independently Published, 2020.

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43

Lewis, Carroll. Through the Looking-Glass and What Alice Found There: Large Print. Independently Published, 2019.

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44

Lewis, Carroll. Through the Looking-Glass and what Alice found there: In large print. Outlook Verlag, 2022.

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45

Lewis, Carroll. Through the Looking Glass (and What Alice Found There). Independently Published, 2021.

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46

Lewis, Carroll. Through the Looking Glass. Independently Published, 2019.

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47

A traves del espejo. Alianza Editorial, 2010.

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48

Through the Looking Glass. Penguin Random House, 1994.

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49

Lewis, Carroll. Through The Looking Glass. Createspace Independent Publishing Platform, 2012.

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50

Through the Looking-Glass. Independently Published, 2017.

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