Academic literature on the topic 'Transplantation of organs, tissues, etc. in children'

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Journal articles on the topic "Transplantation of organs, tissues, etc. in children"

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Krishna, K. Ananda, and K. R. S. Sambasiva Rao. "Bone Marrow Transplantation." Open Biotechnology Journal 3, no. 1 (March 3, 2009): 24–30. http://dx.doi.org/10.2174/1874070700903010024.

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Stem cells are the centre for regenerative medicine. Given a right signal these undifferentiated cells have a remarkable potential to develop into specialized cell types (blood cells, heart cells etc.) in the human body. Stem cells, therefore, can be used in cell-based therapies to replace/repair damaged tissues and/or organs. Ongoing research in the area of stem cells focuses on their potential application (both embryonic stem cells and adult stem cells) to create specialized cells and replace the damaged ones. Hence, this cutting-edge technology might lead to new ways of detecting and treating diseases. Stem cell transplantation can be considered as an option for the treatment of certain type of cancers. This medical procedure can also be used to treat neurological diseases, autoimmune diseases, heart diseases, liver diseases, metabolic disorders, spinal cord injury etc. The present review, therefore, focuses on the growing use of stem cell transplantation in regenerative medicine to treat a variety of diseases. This review also provides the current status of the field with a particular emphasis on bone marrow transplantation.
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Gomes, Alessandra Araujo, Carla Nolasco Monteiro Breviglieri, Natalia Maria Tavares Ferreira Borges, and Gabriele Zamperlini Netto. "Early complications in pediatric hematopoietic stem cell transplantation." JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY 2, no. 4 (November 30, 2021): 125. http://dx.doi.org/10.46765/2675-374x.2021v2n4p125.

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Hematopoietic stem cell transplantation (HSCT) has the potential to cure a significant proportion of patients with malignant and nonmalignant diseases, but the high doses of chemotherapy and/or radiotherapy included in conditioning regimens affect all organs and tissues. In this article, Brazilian Group for Pediatric Bone Marrow Transplantation of the Brazilian Society of Bone Marrow Transplantation and Cellular Therapy (SBTMO) provides a review of early complications in children undergoing HSCT.
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Jovicic, Olivera, Jelena Mandic, Zoran Mandinic, and Aleksandra Colovic. "Oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells." Srpski arhiv za celokupno lekarstvo, no. 00 (2020): 106. http://dx.doi.org/10.2298/sarh190909106j.

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Introduction/Objective. The aim of this paper is to point out the prevalence and severity of oral diseases in patients in the period before and after the transplantation of solid organs and hematopoietic stem cells. Methods. MEDLINE literature search was done via PubMed. Results. The development and improvement of transplantation medicine in specialized centers lead to an increasing number of patients, both adults and children, with transplanted solid organs and hematopoietic stem cells. Despite the success of therapy, numerous changes and complications can be observed on other organs in patients undergoing transplantation of solid organs and hematopoietic stem cells in the pre and post-transplant phase. Systemic diseases and conditions related to organ and cell transplantation, which are accompanied by numerous oral manifestations. The most common oral changes are gingival enlargement, desquamation of the oral epithelium, very painful ulcerations, polypoid and granulomatous changes in the oral mucosa, hard dental tissues with frequent complications, developmental anomalies of teeth in younger children, and in the later stage also the occurrence of oral cancer. After transplantation of solid organs and hematopoietic changes in the oral cavity and other organs occur depending on the patient?s post- transplantation period as well as on the applied immunosuppressive therapy. Conclusion. Oral changes development pre and post transplantation of solid organ and hematopoietic stem cells points to the importance of timely and good cooperation between the dentist and the doctor who treats the underlying disease.
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Amanova, M. A., A. N. Smirnov, V. V. Kholostova, A. G. Mannanov, S. A. Voina, E. Yu Biryukova, and A. I. Khavkin. "Spontaneous perforation of the stomach and duodenum in children with Ehlers‑Danlos syndrome." Experimental and Clinical Gastroenterology 1, no. 1 (March 17, 2021): 176–82. http://dx.doi.org/10.31146/1682-8658-ecg-185-1-176-182.

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Ehlers-Danlos syndrome is based on hereditary systemic dysfunction of the connective tissue caused by impaired collagen synthesis. Depending on the individual mutation, the clinical manifestations of the syndrome can range from mild to life-threatening. The result of a violation of collagen synthesis is the proliferation of elastic fibers, loss of compactness and disorientation of collagen fibers, fragility of the vessel wall and expansion of their lumen. And, given that connective tissue fibers are present in almost every organ, the manifestations of Ehlers-Danlos syndrome are polymorphic and generalized, which often complicates the verification of this disease. The most clinically important is the Ehlers-Danlos Syndrome IV (vascular) type, which occurs as a result of mutations in the COL3A1 and COL1A1 genes and manifests itself in a tendency to spontaneous rupture of large arteries and hollow organs (intestinal perforation, strokes, rupture of the spleen, etc.), poor wound healing, fragility soft tissues, impaired hemostasis. The article describes our own experience of treating 4 patients with spontaneous ruptures of internal organs, including those of a recurrent nature.
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Albán Tigre, Jorge, Andrea Villarreal Juris, Juan Mora Betancourt, and Víctor Betancourt Nole. "TRASPLANTE RENAL EN ECUADOR, PUNTOS CLAVE Y SITUACIÓN ACTUAL." Revista Medica Vozandes 31, no. 2 (January 6, 2021): 42–48. http://dx.doi.org/10.48018/rmv.v31.i2.6.

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IntroductionKidney transplantation in Ecuador began in 1976, it was limited until 2011, when the Organic Law of Donation and Transplantation of Organs, Tissues and Cells became valid. This is indicated in end-stage renal failure, in adult and pediatric patients; and, compared to peritoneal and renal dialysis, it is less expensive for the health system. In 2015, in Ecuador, at least 30,000 people suffered from end-stage kidney disease; 45% of them could die without treatment. The objective of this study was to determine the current situation in Ecuador regarding kidney transplantation. MethodologyA descriptive, retrospective study. INDOT statistics were reviewed from 2007 to August 2019, to determine the total number of transplants and kidney transplants, type of transplant, effective donors, rate of donors per million population (pmp), transplanted organ rate (pmp), evolution of the national waiting list, survival rate, etc. Results From 2007 to 2019, 6134 transplants were performed: 25.4% renal. Most donors were male (68.1%). The donor rate (pmp) between 2009 and 2019 was 4.2 (SD: ± 2.1). The mean rate of transplanted organs was 8.1 (SD: ± 3.6) (pmp) from 2007 to 2019. In this period 1560 kidney transplants were performed: 83.1% with cadaveric donors (88.1% adults; 11.9% pediatric) and 16.9% with living donors (72.4% adults; 27.6% pediatric). The one-year survival rate after cadaveric and living donor kidney transplantation was 0.94 and 0.97 in adults; and 0.90 and 0.97 in pediatrics, respectively. Currently there are only 5 accredited centers for kidney transplantation in adults and one for pediatric kidney transplantation .ConclusionsKidney transplantation has made significant progress in Ecuador, however, it is still below the World Health Organization (WHO) goal established for the proper management of patients with chronic kidney failure.
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Magomedova, A. U., E. A. Fastova, A. M. Kovrigina, T. N. Obukhova, N. I. Skidan, Ya K. Mangasarova, A. I. Vorobyev, and S. K. Kravchenko. "Bone marrow involvement in primary mediastinal B-cell lymphoma." Terapevticheskii arkhiv 89, no. 7 (July 15, 2017): 65–68. http://dx.doi.org/10.17116/terarkh201789765-68.

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Primary mediastinal large B-cell lymphoma (PMBCL) is a distinct type of large B-cell lymphoma. In this type of the disease, the neoplastic process is located in the anterior and superior mediastinum, frequently with compression of the superior vena cava and with tumor invasion into the adjacent organs and tissues: the pericardium, lung, pleura, etc. Despite the fact that in PMBCL progression, there may be involvement of extranodal organs, such as the kidney, adrenal glands, liver, and central nervous system, bone marrow (BM) injury is generally absent. Since BM injury in patients with diffuse large B-cell lymphoma is an independent poor prognostic indicator, there is reason to believe that BM involvement in PMBCL affects the prognosis. These cases may need intensified induction therapy followed by autologous hematopoietic stem cell transplantation; and BM injury should be monitored during the therapy. The paper gives reports of clinical cases of bone marrow involvement in 2 PMBCL patients treated at the National Research Center for Hematology, Ministry of Health of the Russian Federation.
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Tonoyan, Narine. "The Right to physical and mental immunity in the light of the new constitution of the Republic of Armenia and modern challenges in this field in Armenia." Bratislava Law Review 3, no. 2 (December 31, 2019): 84–90. http://dx.doi.org/10.46282/blr.2019.3.2.150.

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The Constitution of the Republic of Armenia (RA) for the first time envisaged the right to physical and mental immunity (in the former edition of personal immunity) in 2015. According to Article 25(1) of the RA Constitution, everyone shall have the right to physical and mental integrity. That right may be restricted only by law, for the purpose of state security, preventing or disclosing crimes, protecting public order, health and morals or the basic rights and freedoms of others. The bodily rights of the person, including the right to physical and mental immunity, are recognized in professional literature as somatic rights that have become a subject of vigorous debates as a new generation of human rights. In general, human somatic (bodily) rights constitute a wholeness, which includes: the right to life; the right to die or the right to choose a way of giving up one’s life (right to suicide, right to use euthanasia), etc. Current report in the light of the RA Constitution report discuss some of important issues in this field: eugenic experiments, medical intervention, organs and tissues transplantation, etc.
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Koren, N. A., T. B. Tkachenko, L. G. Vladimirova, Sh R. Abdullaeva, and E. V. Semenova. "Features of basic indicators of oral fluid in children after hematopoietic cell transplantation (pilot study)." Scientific Notes of the Pavlov University 26, no. 4 (March 21, 2020): 29–33. http://dx.doi.org/10.24884/1607-4181-2019-26-4-29-33.

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Relevance. Treatment of patients with refractory forms of acute lymphoblastic leukemia causes a number of complications from the organs and tissues of the oral cavity. It can be both early complications – cytotoxic reactions with the development of oral mucositis, and late, leading to a violation of the mineralization of hard tooth tissues, and to underdevelopment of the teeth. Oral fluid plays an important role in maintaining oral homeostasis. One of the most important functions that it performs is maintaining the physiological balance of the processes of re- and demineralization of tooth enamel. Since demineralization processes begin in childhood at higher pH values than in adults, when the hydrogen index decreases below 6.4, demineralization processes begin to prevail over remineralization, and the solubility of hydroxylapatite crystals which enamel consists of increases.The objective was to assess the basic indicators of oral fluid and oral hygiene indices in this group of patients.Methods and materials. During the examination of the oral cavity, the intensity of caries and hygiene indices were determined. For the study, oral fluid was collected, followed by determination of its viscosity and hydrogen index.Results. These patients showed a lower level of oral fluid hydrogen index and a lower level of oral hygiene compared to healthy children. In addition, during the study, it was found that there is a direct relationship between the pH of the oral fluid and the time elapsed since the hematopoietic cell transplantation.Conclusion. The detected changes are factors that predispose to an increase in the intensity of caries, and require early preventive measures.Authors declare no conflict of interest.The authors confirm that they respect the rights of the people participated in the study, including obtaining informed consent when it is necessary, and the rules of treatment of animals when they are used in the study. Author Guidelines contains the detailed information.
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Domin, Yu. "LEGAL REGULATION OF TRANSPLANTATION IN UKRAINE: THE CURRENT STATE AND PROSPECTS OF DEVELOPMENT." Scientific Notes Series Law 1, no. 12 (October 2022): 226–31. http://dx.doi.org/10.36550/2522-9230-2022-12-226-231.

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The article is devoted to the characteristics of the current state and existing problems of the legal regulation of transplantation in Ukraine, as well as to the formulation of scientifically based recommendations aimed at its improvement. The works of Ukrainian scientists devoted to certain issues of legal regulation of the transplantation of anatomical materials in Ukraine were analyzed. The latest positive changes in the national legislation in this area are characterized. In particular, it is noted that the identified problems were partially resolved thanks to the adoption of the Law of Ukraine "On Amendments to Certain Laws of Ukraine Regulating the Transplantation of Anatomical Materials to Humans" dated 12/16/2021 No. 1967-IX. The positive provisions of this law were noted. On the basis of the analysis of the current legislation in the field of transplantation of anatomical materials to a person, its shortcomings and gaps were identified and determined. It is about: 1) proper formulation of the principles of transplantation; 2) determination of the legal status of the authorized person of a specialized state institution in the field of transplantation of organs, tissues and cells, 3) the involvement of a forensic medical expert in the extraction of anatomical materials; 4) the issue of legal responsibility for violations of legislation in the field of transplantation of anatomical materials to humans; 5) proper legal regulation of xenotransplantation, etc. It was concluded that despite the positive developments in the field of transplantation, which were caused by the adoption of Law No. 2427-VIII, there are still many issues in Ukraine that require urgent solutions.
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Majid, Marina Abdul. "Combating Malaysia's Involvement in Worldwide Organ Trafficking by Tapping into the Potential of Bioprinting." GATR Global Journal of Business Social Sciences Review 7, no. 1 (February 20, 2019): 61–74. http://dx.doi.org/10.35609/gjbssr.2019.7.1(8).

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Objective - Organ shortages have caused many Malaysian people to travel to India or China to purchase organs illegally and to have those organs transplanted into their body, thus contributing to the worldwide problem of organ trafficking. Bioprinting presents the potential to develop human organs in the future. The objective of this study is to explore, through empirical research, the potential of bioprinting as a means of addressing Malaysia’s organ shortages, thereby discouraging Malaysians from obtaining illicitly acquired organs abroad. Methodology/Technique – This is a qualitative study involving primary data including binding international agreements, soft law (non-binding documents issued by international organizations) and Malaysian legislation dealing with organ trafficking. These legal documents are interpreted through a textual analysis. A content analysis was also conducted on the secondary resources consisting of journals, book chapters, conference and working papers, newspaper reports, and other internet materials. Findings - The results of the study show that between 2014 and 2018, Malaysia experienced significant organ shortages, particularly shortages of kidneys. They also suffered from a lack of transplant specialists and medical teams as well as overburdened government hospitals. The Organ and Tissue Transplantation Bill, a new law replacing the Human Tissues Act of 1974, aims to ban organ trading and regulate organ donations. Malaysian research universities have embraced bioprinting through the production of blood vessels and skin, and the Malaysian government has introduced grants and technology transfers that are hoped to accelerate bioprinting. This has the potential to curb Malaysian involvement in worldwide organ trafficking. Novelty – This study is novel as it proposes bioprinting as a technological solution to illicit organ trading and transplantation within the Malaysian context, which has not been previously suggested. Type of Paper: Review. JEL Classification: K10, K14, K49. Keywords: 2000 Protocol to Prevent, Suppress and Punish Trafficking in Persons, Especially Women and Children; Bioprinting; Guiding Principles on Human Cell; Transplantation Bill; Organ Trafficking.
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Dissertations / Theses on the topic "Transplantation of organs, tissues, etc. in children"

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Pummer-Verté, Lila. "Organ donation and transplantation /." Online version of thesis, 1995. http://hdl.handle.net/1850/12252.

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Van, den Berg Leon. "Organ and tissue donation and transplantation a perspective of South African Baptists from the Baptist Northern Association and its implications for preaching /." Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-10022007-164428/.

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Chudik, John D. "Human fetal tissue transplantation an Orthodox Christian ethical evaluation /." Theological Research Exchange Network (TREN), 1994. http://www.tren.com.

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Fisher, Karen Joan. "Allocating scarce resources an ethical case study of organ transplantation /." Theological Research Exchange Network (TREN), 1997. http://www.tren.com.

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Motallebzadeh, Reza. "Tertiary lymphoid organogenesis in solid organ transplantation." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608121.

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Greenwood, Gay. "The spaces within : a Foucaudian analysis of organ donation discourses /." Title page, table of contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phg81652.pdf.

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Shubane, Nancy. "Black critical care nurses' perceptions of organ donation and organ transplantation." Pretoria : [s.n.], 2009. http://upetd.up.ac.za/thesis/available/etd-10262009-185326/.

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Poliachik, Sandra Louise. "Transplant organ preservation cooler." Thesis, Virginia Tech, 1991. http://hdl.handle.net/10919/41591.

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A method for preserving transplant organs for extended periods of time has been developed in the transplant organ preservation cooler. The preservation cooler enhances organ viability by maintaining a temperature controlled organ bath and pumping perfusate through the transplant organ. The emphasis on the transplant organ preservation cooler is to provide a simple and portable system which will be powered by boiled off oxygen from a liquid oxygen source. The design of the preservation cooler pump and temperature control system are presented. Results of tests proving the successful operation of the preservation cooler prototype are also presented.
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Nagel, Markus. "Organtransplantation und Internationales Privatrecht." Berlin ; Heidelberg : Springer, 2009. http://deposit.d-nb.de/cgi-bin/dokserv?id=3182142&prov=M&dok%5Fvar=1&dok%5Fext=htm.

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Waln, Donna L. "The ethics of fetal tissue research and transplant." Theological Research Exchange Network (TREN), 1998. http://www.tren.com.

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Books on the topic "Transplantation of organs, tissues, etc. in children"

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N, Fine Richard, Harmon William 1943-, and Tejani Amir, eds. Pediatric solid organ transplantation. Copenhagen: Munksgaard, 2000.

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B, Johnson Ann, and Hooper Patricia Lee, eds. Pediatric transplantation. Philadelphia, PA: W.B. Saunders, 1992.

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Amir, Tejani, and Fine Richard N, eds. Pediatric renal transplantation. New York, N.Y: Wiley-Liss, 1994.

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Office, General Accounting. Organ transplants: Increased effort needed to boost supply and ensure equitable distribution of organs : report to congressional committees. Washington, D.C: GAO, 1993.

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Katō, Tomoaki. Ishoku byōtō 24-ji: You have the power to donate life. Tōkyō: Shūeisha, 2005.

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Katō, Tomoaki. Ishoku byōtō 24-ji, akachan o sukue!: You have the power to donate life. Tōkyō: Shūeisha, 2007.

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Office, General Accounting. Organ transplants: Allocation policies include special protections for children : report to Congressional requesters. Washington, DC (P.O. Box 37050, Washington 20013): U.S. General Accounting Office, 2001.

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1945-, Johnson F. Leonard, and Pochedly Carl, eds. Bone marrow transplantation in children. New York: Raven Press, 1990.

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L, Franco Kenneth, ed. Pediatric cardiopulmonary transplantation. Armonk, N.Y: Futura Pub., 1997.

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Scott, Ann. Living donor liver transplantation in children. Edmonton, AB: Alberta Heritage Foundation for Medical Research, 2004.

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