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Dissertations / Theses on the topic 'Transplantation'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Vroemen, Joseph Pieter Anna Maria. "Hepatocyte transplantation." Maastricht : Maastricht : Rijksuniversiteit Limburg ; University Library, Maastricht University [Host], 1987. http://arno.unimaas.nl/show.cgi?fid=5364.

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2

Bour-Guichenez, Gisèle. "Les obstructions urétérales en transplantation rénale : à propos de 16 obstructions concernant 330 transplantations." Saint-Etienne, 1989. http://www.theses.fr/1989STET6220.

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3

Mari, Elisabeth Rose. "Factors affecting the induction of transplantation tolerance in bone marrow transplantation." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9919.

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The engraftment of allogeneic haematopoietic stem cells (HSC) relies on the use partially or fully myeloablative regimens to condition the transplant recipient in order to “make space” in the bone marrow microenvironment and establish immunological tolerance to donor alloantigens. In murine models of bone marrow transplantation where donor-recipient pair differ for a single minor histocompatibility (H) antigen, HY, engraftment can be obtained using low-dose irradiation. Such conditioning favours the homeostatic expansion of regulatory (Treg) cells that play a crucial role in generating host ve

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4

Poyet, Pierre. "Les reflux vésico-urétéraux en transplantation rénale : A propos de 9 reflux concernant 408 transplantations." Saint-Etienne, 1990. http://www.theses.fr/1990STET6217.

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5

Huda, Amina. "Employment after liver transplantation." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2010. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3398878.

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6

Lord, Stephen. "Reinnervation after cardiac transplantation." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410568.

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7

Schafer, Donna. "Hyperlipidemia post heart transplantation." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=69770.

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Hyperlipidemia is prevalent following heart transplantation, and may play a role in the development of late graft atherosclerosis. The charts of 35 heart transplant recipients (n = 32 males and 3 females) were reviewed retrospectively up until three years post transplantation, to describe a time-course of hypercholesterolemia after transplantation, and to determine the mechanisms involved in its pathogenesis. All patients received prednisone, cyclosporine, and azathioprine for immunosuppression. A progressive rise in both serum cholesterol (2.4 $ pm$ 0.4 mmol/l, p $<$ 0.01), and body weight (8

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8

Honey, Karen J. "Mechanisms of transplantation tolerance." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301519.

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9

Wise, Matt. "Mechanisms of transplantation tolerance." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242039.

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10

Jamieson, N. V. "Liver preservation for transplantation." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.605054.

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11

Scully, Ralph. "Mechanisms in transplantation tolerance." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321084.

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12

Bentall, Andrew John. "Antibodies in kidney transplantation." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5817/.

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The aim of this thesis is to examine the effect of anti-donor antibodies in the clinical management and outcomes of antibody incompatible kidney transplantation. Initial studies were conducted to improve measurement of anti-ABO specific blood group antibodies. The specificity of antibody binding to blood group antigens (BGA) depended upon the assay platform and the nature of the core structure to which the BGA was bound. A standardised haemagglutination assay had excellent reproducibility, which was then applied to the analysis of samples derived from a study of 100 ABO incompatible kidney tra

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13

Desai, Rajeev Ramarao. "Organ transplantation related cancer." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6907/.

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Cancer is an important cause of mortality among the recipients of organ transplantation. Cancer transmitted from the donors has poor outcome and the fear of such transmission results in non-acceptance of certain organs. Study of the recipients in the UK over 10 years identified 15 cases of transmitted cancers. The rate of cancer transmission was 0.05%.The risk of cancer transmission was 9 times higher from donors older than 45 years. A comparison of the organ donor data with the guidelines classifying the donor’s risk showed that a selected cohort of donors, who are classed as high risk of can

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14

Fabre, Jean-Michel. "Métabolisme hépatique et transplantation." Montpellier 1, 1994. http://www.theses.fr/1994MON1T013.

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15

Legrand, Éric. "Polyglobulie apres transplantation renale." Nancy 1, 1991. http://www.theses.fr/1991NAN11192.

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16

Lepoivre, Hélène. "Grossesse après transplantation rénale." Caen, 1990. http://www.theses.fr/1990CAEN3085.

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17

Pummer-Verté, Lila. "Organ donation and transplantation /." Online version of thesis, 1995. http://hdl.handle.net/1850/12252.

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18

Wotherspoon, John Scott. "Studies in transplantation tolerance." Thesis, The University of Sydney, 1990. https://hdl.handle.net/2123/26352.

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The most fundamental function of the immune system is discrimination between the molecules that constitute "self" and those of foreign organisms, tissues or substances which the organism encounters during life. This immunological discrimination between self and non-self is vital to the maintenance of the biological integrity of the organism and is evident at the lowest phylogenetic levels (Hildemann et al., 1977). Encounters with molecules which are recognised as non-self trigger the immune system to initiate effector mechanisms by which the foreign molecules are eliminated. The diverse range

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19

CLAYTON, Philip. "Outcomes of Kidney Transplantation." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/10553.

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Kidney transplantation is the preferred treatment for the majority of patients with end-stage kidney disease, offering improved survival and quality of life compared with dialysis at reduced cost. However, kidney transplantation remains a treatment rather than a cure. A good outcome requires appropriate donor and recipient selection, careful management of immunosuppression, and avoidance of long-term complications including death from cardiovascular disease or malignancy, and graft loss from chronic allograft nephropathy or recurrence of the primary kidney disease. Making use of data from the

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20

Quteineh, Lina. "Pharmacogénétique en transplantation rénale." Paris 6, 2008. http://www.theses.fr/2008PA066229.

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1) Étude du polymorphisme génétique de la vitamine K époxyde réductase (VKORC1) et le risque de surdosage en anti-vitamine K (AVK). Précédemment, nous avons réalisé une étude prospective de type cas-témoin dans le but de d’identifier des facteurs de risque de surdosage en AVK. La même population a été ré-analysée, en ajoutant un nouveau facteur génétique (VKORC1 1173C>T). Nous avons montré dans cette étude que le risque de surdosage est significativement plus important chez les patients 1173TT et les patients 1173CT comparativement aux patients 1173CC avec un risque relatif de 10,5 et 2,3 resp

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21

POLLET, BEATRICE. "Transplantation cardiaque et grossesse." Lyon 1, 1991. http://www.theses.fr/1991LYO1M239.

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22

LACAILLE, VERONIQUE. "Hyperlipidemie apres transplantation cardiaque." Dijon, 1994. http://www.theses.fr/1994DIJOM075.

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23

Herjean, Marion Christine. "Les causes de mortalité en transplantation hépatique hors les récidives des pathologies initiales, à propos de 207 transplantations hépatiques." Bordeaux 2, 1996. http://www.theses.fr/1996BOR23071.

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24

Jansson, Monika. "Detection of donor cells in recipient tissues after stem cell transplantation using FISH and immunophenotypi Stem cell transplantationng /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-222-4/.

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25

Huang, C. C. "Pathophysiology of post-transplantation bone disease : mechanisms of bone loss after orthotopic liver transplantation." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604707.

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To enhance our understanding of the pathophysiology of bone disease associated with liver transplantation and of the mechanisms underlying bone loss in the three month period following transplantation, this prospective study was undertaken as follows: (1) bone pathophysiology was evaluated pre- and three months post-transplantation in transiliac biopsies using tetracycline-assisted histomorphometry; (2) cellular activities of bone formation and resorption pre- and post- transplantation were studied using quantitative enzyme cytochemistry in combination with histomorphometric methods; (3) cellu

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26

BORIES, GUERIN EMMANUELLE. "Cancers secondaires apres transplantation : a propos d'un cas de cancer bronchique apres transplantation cardiaque." Rennes 1, 1993. http://www.theses.fr/1993REN1M071.

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27

Cortellazzi, Jacopo. "Code transplantation for adversarial malware." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/17288/.

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In the nefarious fight against attackers, a wide range of smart algorithms have been introduced, in order to block and even prevent new families of malware before their appearance. Machine learning, for instance, recently gained a lot of attention thanks to its ability to use generalization to possibly detect never-before-seen attacks or variants of a known one. During the past years, a lot of works have tested the strength of machine learning in the cybersecurity field, exploring its potentialities and weaknesses. In particular, various studies highlighted its robustness against adversarial a

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28

Sáez, Giménez Berta. "Venous thromboembolism after lung transplantation." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/666689.

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La enfermedad tromboembólica es una complicación frecuente tras el trasplante de órgano sólido y, específicamente, tras el trasplante pulmonar. Los objetivos de nuestro trabajo fueron: describir los factores de riesgo de la enfermedad tromboembólica, evaluar el impacto de un protocolo de profilaxis extendido y describir los perfiles de coagulación antes y hasta 1 año tras el trasplante pulmonar. Con dicho objetivo llevamos a cabo dos estudios; el primero compara retrospectivamente una cohorte estudio (n=138) que recibió profilaxis con enoxaparina 90 días post-trasplante y una cohorte co

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29

Neal, David A. J. "Cardiovascular risk after liver transplantation." Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418005.

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30

ChacoÌn-Chaves, Ronald Alfredo. "Respiratory function after lung transplantation." Thesis, University of Newcastle upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247836.

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31

Brice, Sarah Louise, and sarahlbrice@gmail com. "Regional Immunosuppression for Corneal Transplantation." Flinders University. Medicine, 2010. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20100811.113448.

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Corneal transplantation is performed to restore vision or to relieve pain in patients with damaged or diseased corneas. However, approximately 40% of corneal allografts fail after 10 years. The most common cause of graft failure is irreversible immunological rejection, primarily mediated by CD4+ T cells, despite the topical application of glucocorticosteroids. The aim of this project was to investigate the anatomic site of antigen presentation during corneal transplantation in the rat, by using a lentiviral vector to express an anti-CD4 antibody fragment at potential sites of antigen presentat

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32

Ruers, Theodoor Jacques Marie. "Selective immunosuppression in organ transplantation." Maastricht : Maastricht : Rijksuniversiteit Limburg ; University Library, Maastricht University [Host], 1989. http://arno.unimaas.nl/show.cgi?fid=5415.

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33

Polak, Wojciech Grzegorz. "Technical aspects of liver transplantation." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.

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34

Marelli, Daniel. "Cell transplantation for myocardial repair." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=61231.

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It was hypothesized that skeletal muscle (SKM) satellite cells multiplied in vitro could be used to repair injured heart muscle. The purpose of this study was to test this hypothesis by auto-transplanting SKM satellite cells to a myocardial injury site. Fourteen dogs underwent explanation of the anterior tibialis muscle. Satellite cells were multiplied in vitro and their nuclei were labelled with tritiated thymidine 24 hours prior to implantation. The same dogs were then subjected to a myocardial injury by the application of a cryoprobe. The cells were suspended in serum free growth medium and

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35

Qin, Shi-Xin. "Transplantation tolerance with monoclonal antibodies." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305697.

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36

Leong, Louise Yi Won. "Transplantation tolerance in the adult." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259603.

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37

GracÌ§a, LuiÌs. "Mechanisms of peripheral transplantation tolerance." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249470.

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38

Titus, Thomas T. "Studies on pancreatic islet transplantation." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270180.

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39

Stovold, Rachel. "Gastric aspiration and lung transplantation." Thesis, University of Newcastle Upon Tyne, 2009. http://hdl.handle.net/10443/1709.

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Lung transplantation has become a viable therapeutic option for patients with end-stage lung disease, however, despite improvements in surgical techniques and post-operative management long term survival is poor when compared to those of other solid organ transplants. The long term success is limited by the onset of obliterative bronchiolitis (08) and its clinical correlate bronchiolitis obliterans syndrome (80S). Obliterative bronchiolitis is a chronic pathology involving inflammation and airway fibrosis causing allograft dysfunction. It is thought to occur as a response to both immunological

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40

Hardstaff, Ruth. "Compliance post solid organ transplantation." Thesis, University of Newcastle Upon Tyne, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493240.

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The twentieth century was a time of a lot of advances in medicine, none more so than in the field of transplantation. Thanks to the pioneering work of many different people in a variety of different fields it is now possible to transplant bone marrow and solid organs. Transplantation is a truly multidisciplinary specialty where patient care is shared between physicians and surgeons. As in all medical specialties good nursing care is essential and requires a high degree of specialisation. Pathologists are key in post operative management in order to promptly diagnose problems so that treatment

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41

Eckoldt, Stephanie Martina. "Glycaemic control after pancreas transplantation." Thesis, University of Bristol, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.633150.

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Background: Pancreas transplantation is considered in patients with type 1 diabetes in whom usual medical management is not able to provide adequate glycaemic control or causes frequent severe episodes of hypoglycaemia. Benefits of transplantation in terms of correction of glycaemia (hyper- and hypoglycaemia) must be weighed carefully against risks associated with surgery and lifelong immunosuppression. Improved long-term graft survival would tip the risk-benefit balance in favour of transplantation. It is not clear what factors determine longterm metabolic graft function and there is currentl

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42

Sieunarine, Krishen. "The feasibility of uterine transplantation." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497648.

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43

Agorogiannis, Eleftherios. "TH17 cells in transplantation biology." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540084.

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44

Hosgood, Sarah Anne. "Normothermic perfusion in renal transplantation." Thesis, University of Leicester, 2012. http://hdl.handle.net/2381/10924.

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One of the main causes of early graft dysfunction in kidney transplantation is ischaemia reperfusion (I/R) injury. This unavoidable event occurs immediately when oxygenated blood is re-introduced into the transplanted kidney. Its severity is influenced by many predetermined factors. However, the condition under which an organ is preserved has a significant bearing on the outcome. Traditionally, organs are preserved using hypothermic temperatures, to reduce metabolism and the requirement for oxygen. Although practical and simple, hypothermic conditions are not entirely favourable and over time

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45

勞錦輝 and Kam-fai Simon Lo. "Cytomegalovirus and bone marrow transplantation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1997. http://hub.hku.hk/bib/B31215609.

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46

Al-Muzairai, Ibrahim Abdulaziz. "Antiidiotypic antibodies in renal transplantation." Thesis, University of Aberdeen, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280624.

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Blood transfusion given before transplantation may improve subsequent allograft survival but the mechanism of action remains unknown. Several groups have postulated that the blood transfusion effect in renal transplantation is mediated through idiotypic- antiidiotypic antibody interactions which result in specific immunosuppression. These antibodies were found to be directed towards both class I & II MHC antigens. Cyclosporin has been shown to be effective in abrogating a primary immune response (if administered concomitantly with blood transfusions) but not an established response. Recent stu

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47

Targett, Michael Peter. "Investigations into glial cell transplantation." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627550.

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48

Renshaw, A. "Clinical considerations in facial transplantation." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1322991/.

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Facial transplantation has emerged as the next step on the reconstructive ladder for severe facial disfigurement. Clinical issues surrounding facial tissue donation are examined, comprising pre-transplant facial vessel delineation; pre-operative aesthetic matching; and attitudes towards donation. An anatomical study of 200 consecutive facial and transverse facial vessels was performed using colour Doppler ultrasound. Facial vessels were measured at three landmarks and their branching pattern documented. The facial artery main branch was detected at the lower mandibular border in 99.5% of cases

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49

Kerby, Alan. "Immunoisolation approaches for islet transplantation." Thesis, King's College London (University of London), 2013. https://kclpure.kcl.ac.uk/portal/en/theses/immunoisolation-approaches-for-islet-transplantation(dbea18df-91a3-41c8-b9ba-24666a2a889f).html.

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The widespread use of islet transplantation as a treatment for type 1 diabetes is limited in part by the necessity for long term immunosuppression. The principle of immunoisolation is to create a physical barrier surrounding the islets to prevent immune destruction after implantation, therefore removing the requirement for immunosuppression. Alginate microcapsules are the most commonly used immunoisolation device which are typically implanted intraperitoneally. Intraperitoneal microencapsulated islet grafts are suboptimal, requiring at least double the number of islets to reverse hyperglycaemi

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50

Gingell-Littlejohn, Marc. "Cellular senescence and renal transplantation." Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/4986/.

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With the current crisis of organ shortage and an increasing number of dialysis patients,studies directed at ameliorating such a substantial organ discrepancy are of considerable importance to the transplant community. The use of extended criteria donation has helped to compensate the disparity of organs however, we are still a long way from achieving satisfactory targets. Still there are many organs from older donors that are discarded primarily on the basis of chronological age. It is here that biological age may display a crucial role in allowing the transplant team to characterize donor org

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