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Journal articles on the topic 'Transsexuals sex reassignment process'

Author: Grafiati

Published: 4 June 2021

Last updated: 12 February 2022

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1

Mrsevic, Zorica. "Transsexuals and families: Between discrimination and inclusion." Temida 16, no. 2 (2013): 57–73. http://dx.doi.org/10.2298/tem1302057m.

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The text comprises analysis of family relations of transsexual persons. Its aim is to present the legal solutions of international courts as the way of solving their legal status in family relations. The author presents sentences of the European Court of Human Rights and European Court of Justice as well as the whole range of international treaties, resolutions and other documents of international law, aiming to promote legal importance of the newly gained sex of the transsexuals who passed the genital reassignment process. This is important for the regulation of their marriage and family rela

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2

Vetri, Mario, Alessia Cataldi, and Adriano Naselli. "Gender Identity Disorder Etiology and Medical Treatment: Between Scientific Evidence and Personal Experiences." Journal of Drugs Addiction & Therapeutics 2, no. 2 (2021): 1–12. http://dx.doi.org/10.47363/jdat/2021(2)112.

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Gender Identity Disorder (GID) is a condition characterized by a strong and persistent identification with the opposite sex. These people consider themselves victims of a sort of biological accident: “a soul in a wrong body”. There are numerous theories on the origin of transsexualism: genetic, hormonal and psychological causes have been hypothesized, but those currently most accredited are the neuroanatomical ones. The cornerstones of hormone conversion therapy (Gender Affirming Hormone Therapy, GAHT) are feminizing hormones for transgender women (MtFs or AMAB: Assigned Male at Birth) and vir

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3

Petry, Analídia Rodolpho. "Transgender women and the Gender Reassignment Process: subjection experiences, suffering and pleasure in body adaptation." Revista Gaúcha de Enfermagem 36, no. 2 (2015): 70–75. http://dx.doi.org/10.1590/1983-1447.2015.02.50158.

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OBJECTIVE: This article seeks to understand the experiences of transgender women in relation to the hormone therapy and sex reassignment surgery that make up the Gender Reassignment Process. METHOD: It is a qualitative study inserted into the field of cultural and gender studies. Data collection used narrative interviews, conducted in 2010 and 2011, with seven transsexual women who had been undergoing the Gender Reassignment Process for at least two years. The data was submitted to a thematic analysis. RESULTS: The results show that the transformation processes for construction of the female b

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4

Barišić, Jasmina, Marija Milosavljević, Dragana Duišin, Borjanka Batinić, Svetlana Vujović, and Srdjan Milovanović. "Assessment of Self-Perception of Transsexual Persons: Pilot Study of 15 Patients." Scientific World Journal 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/281326.

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Background and Aims. There have been few studies in the area of Self-Perception in transsexual persons, except for the population of transsexual adolescents. Bearing in mind its importance not only in the assessment of personality but also in predicting adaptive capacity, the goal of our research is based on the examination of Self-Perception of adult transsexual persons.Method. The study was conducted using a Rorschach test, which provides an insight into various aspects of Self-Perception. The sample consisted of 15 transsexual persons, who passed the standard diagnostic procedure.Results. T

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5

Jokić-Begić, Nataša, Anita Lauri Korajlija, and Tanja Jurin. "Psychosocial Adjustment to Sex Reassignment Surgery: A Qualitative Examination and Personal Experiences of Six Transsexual Persons in Croatia." Scientific World Journal 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/960745.

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In Croatia, transgender individuals face numerous social and medical obstacles throughout the process of transition. The aim of this study was to depict the factors contributing to the psychosocial adjustment of six transsexual individuals living in Croatia following sex reassignment surgery (SRS). A combination of quantitative and qualitative self-report methods was used. Due to the specificity of the sample, the data were collected online. Standardized questionnaires were used to assess mental health and quality of life alongside a series of open-ended questions divided into 4 themes: the de

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6

Snaith, Philip, Michael J. Tarsh, and Russell Reid. "Sex Reassignment Surgery." British Journal of Psychiatry 162, no. 5 (1993): 681–85. http://dx.doi.org/10.1192/bjp.162.5.681.

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“This is an evaluation of the therapeutic effect of sex reassignment surgery on 36 female-to-male transsexuals and 105 male-to-female transsexuals in the Netherlands. Data were collected by means of structured interviews. The evaluation was made on the basis of subjective data only, that is on what the persons themselves reported on their gender identity, gender role, and physical condition. Allowing for the restrictive methodology of the (ex post facto) study, it is concluded that there is no reason to doubt the therapeutic effect of sex reassignment surgery. No specific differences were foun

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7

Guevin, Benedict M. "Sex Reassignment Surgery for Transsexuals." National Catholic Bioethics Quarterly 5, no. 4 (2005): 719–34. http://dx.doi.org/10.5840/ncbq2005547.

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8

Wroblewski, Peter, Jonas Gustafsson, and Gennaro Selvaggi. "Sex reassignment surgery for transsexuals." Current Opinion in Endocrinology & Diabetes and Obesity 20, no. 6 (2013): 570–74. http://dx.doi.org/10.1097/01.med.0000436190.80104.56.

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9

Bouman, F. G. "Sex Reassignment Surgery in Male to Female Transsexuals." Annals of Plastic Surgery 21, no. 4 (1988): 397. http://dx.doi.org/10.1097/00000637-198810000-00022.

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10

Bouman, F. G. "Sex Reassignment Surgery in Male to Female Transsexuals." Annals of Plastic Surgery 21, no. 6 (1988): 526–31. http://dx.doi.org/10.1097/00000637-198812000-00006.

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11

Spehr, Christiane. "Male-to-Female Sex Reassignment Surgery in Transsexuals." International Journal of Transgenderism 10, no. 1 (2007): 25–37. http://dx.doi.org/10.1300/j485v10n01_05.

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12

Blanchard, Ray, Betty W. Steiner, Leonard H. Clemmensen, and Robert Dickey. "Prediction of Regrets in Postoperative Transsexuals." Canadian Journal of Psychiatry 34, no. 1 (1989): 43–45. http://dx.doi.org/10.1177/070674378903400111.

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This study investigated whether heterosexual males are more likely to regret sex reassignment surgery than homosexual males or females. Subjects were 111 postoperative transsexuals who had been surgically reassigned for at least one year, representing a follow-up rate of 84.1%. Subjects' feelings about surgery were assessed with self-administered questionnaires. None of the 61 homosexual females or 36 homosexual males consciously regretted surgery, compared to 4 of the 14 heterosexual males: a significant difference. This finding suggests that heterosexual applicants for sex reassignment shoul

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13

COHEN-KETTENIS, PEGGY T., and STEPHANIE H. M. VAN GOOZEN. "Sex Reassignment of Adolescent Transsexuals: A Follow-up Study." Journal of the American Academy of Child & Adolescent Psychiatry 36, no. 2 (1997): 263–71. http://dx.doi.org/10.1097/00004583-199702000-00017.

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14

Kuiper, Bram, and Peggy Cohen-Kettenis. "Sex reassignment surgery: A study of 141 dutch transsexuals." Archives of Sexual Behavior 17, no. 5 (1988): 439–57. http://dx.doi.org/10.1007/bf01542484.

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15

Vasilenko, L., and L. Gorobetz. "P01.72 Psychosocial status of female transsexuals after surgical sex reassignment." European Psychiatry 15, S2 (2000): 339s. http://dx.doi.org/10.1016/s0924-9338(00)94479-1.

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16

Chong, Joyce Ma Lai. "Social Assessment of Transsexuals Who Apply for Sex Reassignment Therapy." Social Work in Health Care 14, no. 3 (1990): 87–105. http://dx.doi.org/10.1300/j010v14n03_06.

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17

Rolle, Luigi, Marco Falcone, Sergio Vighetti, et al. "Does Sex Reassignment Surgery Induce Cerebral Modifications in MTF Transsexuals?" Journal of Sexual Medicine 11, no. 1 (2014): 312. http://dx.doi.org/10.1111/jsm.12355.

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18

Jackowich, Robyn A., Thomas W. Johnson, Pierre Brassard, Maud Bélanger, and Richard Wassersug. "Age of Sex Reassignment Surgery for Male-to-Female Transsexuals." Archives of Sexual Behavior 43, no. 1 (2013): 13–15. http://dx.doi.org/10.1007/s10508-013-0217-7.

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19

Chokrungvaranont, Prayuth, Gennaro Selvaggi, Sirachai Jindarak, et al. "The Development of Sex Reassignment Surgery in Thailand: A Social Perspective." Scientific World Journal 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/182981.

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This paper reviews the development of gender reassignment in Thailand during the period of 1975–2012, in terms of social attitude, epidemiology, surgical patients’ profile, law and regulation, religion, and patients’ path from psychiatric assessment to surgery. Thailand healthcare for transsexual patients is described. Figures related to the number of sex reassignment surgeries performed in Thailand over the past 30 years are reported. Transsexual individuals are only apparently integrated within the Thail society: the law system of Thailand in fact, does not guarantee to transsexuals the same

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20

Keown, John. "FUNDING “SEX-CHANGE” OPERATIONS." Cambridge Law Journal 59, no. 2 (2000): 235–72. http://dx.doi.org/10.1017/s0008197300280100.

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A CASE which will be of interest to students of medical law, public law and human rights, North West Lancashire Health Authority v. A, D, & G [1999] Lloyd's Rep. Med. 399, concerned three transsexuals who wanted “sex-change” operations. The health authority's policy was to give low funding priority to procedures it considered of little or no clinical benefit; the authority would not fund “gender reassignment” except in cases of “overriding clinical need” or other exceptional circumstances, though it would fund psychotherapy.

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21

Ishak, Mohd Shuhaimi Bin Haji, and Sayed Sikandar Shah Haneef. "Sex Reassignment Technology: The Dilemma of Transsexuals in Islam and Christianity." Journal of Religion and Health 53, no. 2 (2012): 520–37. http://dx.doi.org/10.1007/s10943-012-9656-z.

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22

Lobato, Maria Inês Inês, Walter José Koff, Carlo Manenti, et al. "Follow-Up of Sex Reassignment Surgery in Transsexuals: A Brazilian Cohort." Archives of Sexual Behavior 35, no. 6 (2006): 711–15. http://dx.doi.org/10.1007/s10508-006-9074-y.

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23

Bogliolo, Stefano, Chiara Cassani, Luciana Babilonti, et al. "Robotic Single-Site Surgery for Female-to-Male Transsexuals: Preliminary Experience." Scientific World Journal 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/674579.

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Hysterectomy with bilateral salpingo-oophorectomy is a part of gender reassignment surgery for the treatment of female-to-male transsexualism. Over the last years many efforts were made in order to reduce invasiveness of laparoscopic and robotic surgery such as the introduction of single-site approach. We report our preliminary experience on single-site robotic hysterectomy for cross-sex reassignment surgery. Our data suggest that single-site robotic hysterectomy is feasible and safe in female-to-male transsexualism with some benefits in terms of postoperative pain and aesthetic results.

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24

Asscheman, Henk, Erik J. Giltay, Jos A. J. Megens, W. (Pim) de Ronde, Michael A. A. van Trotsenburg, and Louis J. G. Gooren. "A long-term follow-up study of mortality in transsexuals receiving treatment with cross-sex hormones." European Journal of Endocrinology 164, no. 4 (2011): 635–42. http://dx.doi.org/10.1530/eje-10-1038.

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ObjectiveAdverse effects of long-term cross-sex hormone administration to transsexuals are not well documented. We assessed mortality rates in transsexual subjects receiving long-term cross-sex hormones.DesignA cohort study with a median follow-up of 18.5 years at a university gender clinic.MethodsMortality data and the standardized mortality rate were compared with the general population in 966 male-to-female (MtF) and 365 female-to-male (FtM) transsexuals, who started cross-sex hormones before July 1, 1997. Follow-up was at least 1 year. MtF transsexuals received treatment with different hig

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25

Bizic, Marta, Vladimir Kojovic, Dragana Duisin, et al. "An Overview of Neovaginal Reconstruction Options in Male to Female Transsexuals." Scientific World Journal 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/638919.

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Transsexualism is a complex condition in which the person experiences the inconsistency between the desired gender and their biological gender. Absence of the vagina is devastating in male to female transsexuals. Creation of the neovagina is the main surgical problem in these patients. Historically, beginnings of the neovaginal creation have their roots in the treatment of Mayer-Rokitansky syndrome and conditions such as cloacal anomalies, certain intersex disorders, vaginal malignancies, or severe vaginal trauma, but have more recently found great purpose in male to female sex reassignment su

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26

SMITH, YOLANDA L. S., STEPHANIE H. M. VAN GOOZEN, ABRAHAM J. KUIPER, and PEGGY T. COHEN-KETTENIS. "Sex reassignment: outcomes and predictors of treatment for adolescent and adult transsexuals." Psychological Medicine 35, no. 1 (2005): 89–99. http://dx.doi.org/10.1017/s0033291704002776.

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27

Liguori, G., C. Trombetta, L. Salamè, S. Bucci, G. Garaffa, and E. Belgrano. "V36 Sex reassignment surgery for male-to-female transsexuals: An urological job." European Urology Supplements 3, no. 2 (2004): 228. http://dx.doi.org/10.1016/s1569-9056(04)90887-1.

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28

Djordjevic, Miroslav L., Marta R. Bizic, Dragana Duisin, Mark-Bram Bouman, and Marlon Buncamper. "Reversal Surgery in Regretful Male-to-Female Transsexuals After Sex Reassignment Surgery." Journal of Sexual Medicine 13, no. 6 (2016): 1000–1007. http://dx.doi.org/10.1016/j.jsxm.2016.02.173.

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29

Bainham, Andrew. "DOES SEX MATTER?" Cambridge Law Journal 61, no. 1 (2002): 1–52. http://dx.doi.org/10.1017/s0008197302361506.

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ARE sex or gender crucial components of modern marriage? In Bellinger v. Bellinger [2001] EWCA Civ 1140, [2001] 2 F.L.R. 1048, the Court of Appeal returned to the question of the relevance of biological sex to the validity of marriage, first considered thirty years ago by Ormrod J. in Corbett v. Corbett (otherwise Ashley) [1971] P. 83. Both cases involved male-to-female transsexuals who had undergone gender reassignment surgery but in Bellinger, Mrs. Bellinger sought a declaration under section 55 of the Family Law Act 1986 that her marriage to Mr. Bellinger was valid at its inception and stil

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30

De Cuypere, G., E. Elaut, G. Heylens, et al. "Long-term follow-up: psychosocial outcome of Belgian transsexuals after sex reassignment surgery." Sexologies 15, no. 2 (2006): 126–33. http://dx.doi.org/10.1016/j.sexol.2006.04.002.

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31

Kojovic, V., M. Bizic, S. Kojic, et al. "S315: Reversal surgery in regretful male to female transsexuals after sex reassignment surgery." European Urology Supplements 13, no. 7 (2014): e1619. http://dx.doi.org/10.1016/s1569-9056(14)61821-2.

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32

Trombetta, C., G. Liguori, M. Pascone, et al. "Total sex-reassignment surgery in female-to-male transsexuals: a one-stage technique." BJU International 90, no. 7 (2002): 754–57. http://dx.doi.org/10.1046/j.1464-410x.2002.03009.x.

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33

Vasilenko, L. M. "Complex therapy in sex reassignment process." European Psychiatry 13, S4 (1998): 287s. http://dx.doi.org/10.1016/s0924-9338(99)80556-2.

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34

Ma, Joyce L. C. "Social Work Practice with Transsexuals in Hong Kong Who Apply for Sex Reassignment Surgery." Social Work in Health Care 29, no. 2 (1999): 85–103. http://dx.doi.org/10.1300/j010v29n02_05.

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35

Xia, Z. J., C. Wang, and J. Joris Hage. "The Application of Human Ovaries and Testes Cross-Sex Transplantation in Sex Reassignment Surgery of Transsexuals (Abstract)." Plastic and Reconstructive Surgery 95, no. 1 (1995): 201. http://dx.doi.org/10.1097/00006534-199501000-00046.

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36

Soley-Beltran, Patrícia. "Transsexualism in Spain: A Cultural and Legal Perspective." Sociological Research Online 12, no. 1 (2007): 105–17. http://dx.doi.org/10.5153/sro.1474.

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In this paper I will present an overview of the current legal, social and political situation of transsexual and transgendered people in Spain. The study is based on qualitative data gathered from in-depth interviews with transsexual people, transgendered activists and legal experts in Spain, including some aspects of a cross-cultural comparison between Spain and the UK. The empirical study accounts for the development of social policies related to sex-reassignment and their evolution in the last decade in Spain, as well as for transsexual associations and activism, issues of social exclusion

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37

Salvador, Jaqueline, Raffael Massuda, Tahiana Andreazza, et al. "Minimum 2-year follow up of sex reassignment surgery in Brazilian male-to-female transsexuals." Psychiatry and Clinical Neurosciences 66, no. 4 (2012): 371–72. http://dx.doi.org/10.1111/j.1440-1819.2012.02342.x.

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38

Lawrence, Anne A. "Autogynephilia and the Typology of Male-to-Female Transsexualism." European Psychologist 22, no. 1 (2017): 39–54. http://dx.doi.org/10.1027/1016-9040/a000276.

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Abstract. Sexual scientists have recognized for over a century that biologic males who seek sex reassignment – male-to-female (MtF) transsexuals – are not a homogeneous clinical population but comprise two or more distinct subtypes with different symptoms and developmental trajectories. The most widely used typologies of MtF transsexualism have been based on sexual orientation and have distinguished between persons who are androphilic (exclusively sexually attracted to males) and those who are nonandrophilic (sexually attracted to females, both males and females, or neither gender). In 1989, p

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39

Vukadinovic, Vojkan, Borko Stojanovic, Marko Majstorovic, and Aleksandar Milosevic. "The Role of Clitoral Anatomy in Female to Male Sex Reassignment Surgery." Scientific World Journal 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/437378.

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Introduction. Controversies on clitoral anatomy and its role in female sexual function still make clitoral reconstructive surgery very challenging. We evaluated the role of clitoral anatomic features in female to male sex reassignment surgery.Material and Methods. The study included 97 female transsexuals, aged from 18 to 41 years, who underwent single stage metoidioplasty between March 2008 and January 2013. The operative technique involved vaginectomy, the release of clitoral ligaments and urethral plate, urethroplasty by combining buccal mucosa graft and genital flaps, and scrotoplasty with

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40

Ozata, B., S. Yüksel, H. Noyan, M. Avayu, and E. Yildizhan. "EPA-0185 - Effects of sex reassignment surgery on quality of life and mental health in transsexuals." European Psychiatry 29 (2014): 1. http://dx.doi.org/10.1016/s0924-9338(14)77643-6.

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41

Gómez-Gil, Esther, Angela Vidal-Hagemeijer, and Manel Salamero. "MMPI–2 Characteristics of Transsexuals Requesting Sex Reassignment: Comparison of Patients in Prehormonal and Presurgical Phases." Journal of Personality Assessment 90, no. 4 (2008): 368–74. http://dx.doi.org/10.1080/00223890802108022.

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42

Kuhn, Annette, Alessandro Santi, and Martin Birkhäuser. "Vaginal prolapse, pelvic floor function, and related symptoms 16 years after sex reassignment surgery in transsexuals." Fertility and Sterility 95, no. 7 (2011): 2379–82. http://dx.doi.org/10.1016/j.fertnstert.2011.03.029.

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43

Prunas, Antonio, Elisa Bandini, Alessandra D. Fisher, et al. "Experiences of Discrimination, Harassment, and Violence in a Sample of Italian Transsexuals Who Have Undergone Sex-Reassignment Surgery." Journal of Interpersonal Violence 33, no. 14 (2016): 2225–40. http://dx.doi.org/10.1177/0886260515624233.

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The present study aims to provide an overview of experiences of discrimination, harassment, and violence in a sample of Italian transsexuals who have undergone sex-reassignment surgery (SRS). Lack of support for gender transition from family members was also assessed, before and after SRS. Data were collected in the context of a multicentric study (Milan, Florence, and Bari) on SRS outcome. Patients who underwent SRS were contacted and asked to fill out a questionnaire concerning experiences of discrimination, harassment, violence, and crime they might have experienced in previous years. Seven

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44

Meriggiola, M. C., E. A. Jannini, A. Lenzi, M. Maggi, and C. Manieri. "Endocrine treatment of transsexual persons: an Endocrine Society Clinical Practice Guideline: commentary from a European perspective." European Journal of Endocrinology 162, no. 5 (2010): 831–33. http://dx.doi.org/10.1530/eje-09-1091.

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The treatment of transsexual subjects is a challenging task for the endocrinologist who, in collaboration with the mental health professional and the surgeon, is called upon to confirm the diagnosis and adjust hormonal treatment aimed at suppressing endogenous sex hormones and to develop hormone characteristics of the desired gender. These guidelines are structured to provide evidence-based suggestions or, where evidence is lacking, expert recommendations on diagnostic procedures and hormonal treatment in adolescent and adult transsexuals, including long-term care and eligibility for surgery.

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Cova, M., E. Mosconi, G. Liguori, et al. "Value of magnetic resonance imaging in the evaluation of sex-reassignment surgery in male-to-female transsexuals*." Abdominal Imaging 28, no. 5 (2003): 728–32. http://dx.doi.org/10.1007/s00261-002-0100-9.

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46

Gómez-Gil, Esther, Leire Zubiaurre-Elorza, Isabel Esteva de Antonio, Antonio Guillamon, and Manel Salamero. "Determinants of quality of life in Spanish transsexuals attending a gender unit before genital sex reassignment surgery." Quality of Life Research 23, no. 2 (2013): 669–76. http://dx.doi.org/10.1007/s11136-013-0497-3.

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47

Astutik, Yeni, and Anjar Sri Ciptorukmi Nugraheni. "PENGGANTIAN KELAMIN BAGI TRANSEKSUAL DAN AKIBAT HUKUMNYA TERHADAP KEABSAHAN PERKAWINAN DITINJAU DARI UNDANG-UNDANG NOMOR 1 TAHUN 1974 TENTANG PERKAWINAN." Jurnal Privat Law 8, no. 2 (2020): 331. http://dx.doi.org/10.20961/privat.v8i2.48428.

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<p>Abstract<br />This article aims to examine the ratification of changes in legal status and gender replacement procedures in population documents for transsexuals in Indonesia, as well as the legality of marriages for transsexuals in terms of Law Number 1 of 1974 concerning Marriage. The research method used is a type of normative legal research, with a qualitative approach. The legal materials used are primary and secondary legal materials, with data collection techniques used are literature study or document study techniques. Based on the results of the study, it was concluded

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48

Mate-Kole, Charles, Maurizio Freschi, and Ashley Robin. "Aspects of Psychiatric Symptoms at Different Stages in the Treatment of Transsexualism." British Journal of Psychiatry 152, no. 4 (1988): 550–53. http://dx.doi.org/10.1192/bjp.152.4.550.

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Three groups of male transsexuals at different stages of the treatment process were examined and shown to match retrospectively in actuarial and psychiatric data. Transsexuals who were on a waiting list for surgery showed lower neurotic scores on the Crown–Crisp Experiential Index than those at the assessment stage of clinic attendance, while post-operative transsexuals obtained scores lower than either of the other groups. Transsexuals during the assessment stage of treatment obtained the lowest scores on items in the Bern Sex Role Inventory that define stereotypical masculine characteristics

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49

Djordjevic, Miroslav L., Dusan Stanojevic, Marta Bizic, et al. "ORIGINAL RESEARCH–INTERSEX AND GENDER IDENTITY DISORDERS: Metoidioplasty as a Single Stage Sex Reassignment Surgery in Female Transsexuals: Belgrade Experience." Journal of Sexual Medicine 6, no. 5 (2009): 1306–13. http://dx.doi.org/10.1111/j.1743-6109.2008.01065.x.

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50

Mueller, Andreas, Ralf Dittrich, Helge Binder, et al. "High dose estrogen treatment increases bone mineral density in male-to-female transsexuals receiving gonadotropin-releasing hormone agonist in the absence of testosterone." European Journal of Endocrinology 153, no. 1 (2005): 107–13. http://dx.doi.org/10.1530/eje.1.01943.

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Objective: To study the effect of estrogen (E) on the male skeleton in the absence of testosterone (T). Design: Retrospective analyses of 40 middle-aged transsexuals treated with subcutaneous injections of gonadotropin-releasing hormone agonist every 4 weeks and oral 17-beta-estradiol-valerat 6 mg/day over two years until reassignment surgery. Methods: The bone mineral density (BMD) in the femoral neck and lumbar spine (L2–L4) was measured with dual-energy X-ray absorptiometry at the beginning of cross-sex hormone treatment, after 12 and 24 months, and serum T, E, sex hormone-binding globulin

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