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Journal articles on the topic 'Traumatic eosinophilic granuloma'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Inoferio, Katrina Samantha, Rose Lou Marie Agbay, and Jose Carnate. "Traumatic Ulcerative Granuloma with Stromal Eosinophilia." Philippine Journal of Otolaryngology Head and Neck Surgery 34, no. 2 (2019): 55–57. http://dx.doi.org/10.32412/pjohns.v34i2.1127.

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A 41-year-old man presented with an 8-year history of recurrent mouth ulcers, previously treated with unrecalled antibiotics and vitamins but with no relief. Examination showed a 2.0 x 1.0 cm hard, immovable ulcer at the right lateral tongue. On further interview, a history of repeated biting trauma on the site of the lesion was elicited. The clinical impression was a non-healing tongue ulcer. Incision biopsy of the lesion was performed and the specimen sent for histopathologic evaluation. The specimen consisted of three, cream-tan, irregularly-shaped soft tissues measuring up to 0.9 cm

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DE CARVALHO, LAURA PRISCILA BARBOZA, LAUDENICE LUCENA PEREIRA, DIEGO DANTAS MOREIRA DE PAIVA, KAROLINE GOMES DA SILVEIRA, GUILHERME COSTA GUEDES PEREIRA, and MARCOS ANTÔNIO FARIAS DE PAIVA. "Traumatic Eosinophilic Granuloma: A Case Report." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 120, no. 2 (2015): e74-e75. http://dx.doi.org/10.1016/j.oooo.2015.02.329.

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Keshwar, Shashi, Toniya Raut, Mehul Rajesh Jaisani, and Ashish Shrestha. "Traumatic Ulcerative Granuloma with Stromal Eosinophilia: Sinister Appearing Innocuous Lesion." Birat Journal of Health Sciences 6, no. 2 (2021): 1579–81. http://dx.doi.org/10.3126/bjhs.v6i2.40361.

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Trauma within the oral cavity is one of the common incidence of occurrence which can be an inducer as well as propagator for wide range of oral lesion of diverse course. A unique combination of formation of granulomatous lesion with reactive eosinophilic stromal infiltration in response of trauma is “traumatic ulcerative granuloma with stromal eosinophilia (TUGSE)”. It is a reactive, infrequent, self-limiting condition of oral mucosa. The commonly involved site and the clinical presentation might click to suspect it as a lesion of oral cancer. Clinical history and examination guide through the

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4

DOĞAN, Güleç Mert, and Ahmet SIĞIRCI. "A Case of Eosinophilic Granuloma Presenting as Post-traumatic Scalp Hematoma." Turkiye Klinikleri Journal of Case Reports 28, no. 3 (2020): 206–10. http://dx.doi.org/10.5336/caserep.2020-74185.

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5

Pawar, R. V., M. Hagiwara, S. Milla, J. Wisoff, and A. E. George. "Eosinophilic Granuloma Presenting as Post-Traumatic Scalp Hematoma with Epidural Hemorrhage." Neuroradiology Journal 24, no. 5 (2011): 767–71. http://dx.doi.org/10.1177/197140091102400516.

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Al-mousa, Alaa, Mohammed Altarawneh, Omar Alqatawneh, Zalina Bashir, Salem Al-Dwairy, and Anan Shtaya. "Eosinophilic Granuloma of the Skull Presenting as Non-Traumatic Extradural Haematoma in Children." International Journal of General Medicine Volume 13 (November 2020): 1229–34. http://dx.doi.org/10.2147/ijgm.s288512.

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7

Ficarra, G., F. Prignano, and P. Romagnoli. "Traumatic eosinophilic granuloma of the oral mucosa: a CD30+(Ki-1) lymphoproliferative disorder?" Oral Oncology 33, no. 5 (1997): 375–79. http://dx.doi.org/10.1016/s1368-8375(97)00014-6.

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8

Godfrey, R. M., and P. Sloan. "Traumatic (eosinophilic) granuloma of oral soft tissues: A report of two cases with pseudo-lymphomatous features." British Journal of Oral and Maxillofacial Surgery 23, no. 5 (1985): 351–54. http://dx.doi.org/10.1016/0266-4356(85)90007-5.

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9

Lakshmanan, Somu, Srinivasan Venkataraman, and Urvashi Singh. "Riga-Fede disease: a mimicker of malignancy." BMJ Case Reports 14, no. 3 (2021): e235976. http://dx.doi.org/10.1136/bcr-2020-235976.

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Riga-Fede disease (RFD), also known as traumatic eosinophilic granuloma, is a benign inflammatory condition of the oral cavity that may mimic a malignant tumour. It’s a rare condition mainly reported in infants. We present a unique case report of a 57-year-old man who presented to our outpatient department with foreign body sensation in the throat and swelling over the dorsum of the tongue for a period of 1 month. He gave no history of trauma, especially due to sharp teeth. Video laryngoscopy done revealed an ulceroproliferative growth on the midline of the dorsum of the tongue. With clinical

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10

Mehta, Sangita Sharma, and Rajeshwari K. Muthusamy. "Traumatic ulcerative granuloma with stromal eosinophilia: a series of four cases with review of literature." Journal of Pathology of Nepal 10, no. 2 (2020): 1779–82. http://dx.doi.org/10.3126/jpn.v10i2.24596.

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Most of the oral ulcers are traumatic in origin due to sharp tooth and self bite. Traumatic ulcerative granuloma with stromal eosinophilia is a chronic benign lesion of the oral mucosa with uncertain histogenesis. Trauma was proposed to be an inciting factor. A series of four cases of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the lateral borders of the tongue were analyzed regarding oral hygiene, sharp tooth, clinical presentation, histology, and follow-up. The lesion manifests as a small solitary ulcer with induration in the oral mucosa mimicking malignancy. Histology

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11

Muñoz-Grez, Camila, and Constanza Ulloa-Bequer. "Traumatic ulcerative granuloma with stromal eosinophilia, an unusual clinical manifestation in the oral mucosa. Case report." Journal of Oral Research 10, no. 2 (2021): 1–5. http://dx.doi.org/10.17126/joralres.2021.017.

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Introduction: Traumatic ulcerative granuloma with stromal eosinophilia is an uncommon condition of the oral mucosa with a chronic course, usually affecting the tongue. Case Report: Clinically it presents as a chronic ulcer, with raised and indurated borders, rarely presented as a tumor. Histologically it shows a diffuse mixed inflammatory infiltrate, rich in eosinophils. The etiology of this lesion is still unclear; however, chronic irritation from traumatic agents is considered a major initiating factor. In some cases, the presence of CD30+ mononuclear cells within the lesions suggest the pos

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12

Chavan, SateeshS, and Purushotham Reddy. "Traumatic ulcerative eosinophillic granuloma with stromal eosinophilia of tongue." South Asian Journal of Cancer 2, no. 3 (2013): 144. http://dx.doi.org/10.4103/2278-330x.114128.

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13

Al-Talqani, Mustafa B., Bashar H. Abdullah та Ameer D. Hameedi. "Clinicopathological and Immunohistochemical Analysis of 21 cases of Traumatic Ulcerative Granuloma with Stromal Eosinophilia Using CD30, CD68 and TGF-β1". Journal of Baghdad College of Dentistry 30, № 4 (2018): 45–53. http://dx.doi.org/10.26477/jbcd.v30i4.2554.

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Background: Traumatic ulcerative granuloma with stromal eosinophilia is an impressive benign chronic ulcerative lesion of the oral mucosa with vague etiopathogenesis. It was supposed to represent an oral counterpart of primary cutaneous CD30+ lymphoproliferative disorder. Histopathologically, it is characterized by mixed inflammatory infiltrate predominated by histiocytes, lymphocytes and eosinophils along with presence of scattered large atypical mononuclear cells. It has worrisome clinical presentation. It may heal spontaneously, but in most occasions it persists and never heal unless remove

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14

Tsouma, Nikoleta, and Evangelos Liappis. "Riga-Fede disease: A challenging disease for neonates and parents: An up-to-date view of the literature." Balkan Journal of Dental Medicine 28, no. 3 (2024): 168–71. http://dx.doi.org/10.5937/bjdm2403168t.

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Background/Aim: Riga-Fede disease (RFD) is a severe complication of natal and neonatal teeth. It is a benign traumatic granuloma that causes several problems to both the nursing mother and the infant. However, the disease may appear to older children as well. The aim of this study is to investigate the epidemiological and clinical features of Riga-Fede disease, as well as the modern approaches regarding its management. Material and Methods: A thorough investigation of modern literature was conducted, using the scientific databases PubMed and Google Scholar. Published articles of case reports,

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15

Pai, Anuradha, Karthik D. Yadav, Ramakrishna T, and Abhishek B. "The harmless imitator of OSCC: TUGSE - traumatic ulcerative granuloma with stromal eosinophilia." International Journal of Dental Research 5, no. 2 (2017): 199. http://dx.doi.org/10.14419/ijdr.v5i2.8499.

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Traumatic Ulcerative Granuloma with Stromal Eosinophillia is a rare, benign, self-limiting and asymptomatic lesion that shows a spontaneous regression. Its etiopathogenesis is an enigma, but trauma seems to play a role for the occurrence of this lesion. Clinically it manifests as an isolated long standing lesion predominantly located in the tongue, demonstrating raised & indurated margins and mimicking oral squamous-cell carcinoma. Microscopically it is characterized by an inflammatory infiltrate rich in eosinophils. Since these lesions show delayed healing, treatment becomes necessary, bu

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16

Sethi, Aashka, Akanksha Banga, Ritika Raja, and Reema Raina. "Traumatic ulcerative granuloma with stromal eosinophilia." Indian Journal of Dental Research 31, no. 4 (2020): 636. http://dx.doi.org/10.4103/ijdr.ijdr_330_18.

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17

Hirshberg, Abraham, Ninette Amariglio, Sharon Akrish, et al. "Traumatic Ulcerative Granuloma With Stromal Eosinophilia." American Journal of Clinical Pathology 126, no. 4 (2006): 522–29. http://dx.doi.org/10.1309/afha406gbt0n2y64.

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18

Zengming, Xiao, He Maolin, Zhan Xinli, and Chen Qianfen. "Anterior transsternal approach for a lesion in the upper thoracic vertebral body." Journal of Neurosurgery: Spine 13, no. 4 (2010): 461–68. http://dx.doi.org/10.3171/2010.4.spine09808.

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Object Access to the upper thoracic vertebrae has been hampered by numerous anatomical structures and is further impaired by the transition from cervical lordosis to thoracic kyphosis. Therefore, the authors endeavored to study an anterior transsternal approach for upper thoracic disease (T1–4). Methods Fifty-four patients with upper thoracic disease underwent anterior decompression and fusion with sternotomy. Ages in the 33 men and 21 women ranged from 37 to 69 years (average 49 years). Before surgery, there were 7 patients with Frankel Grade B function, 17 with Grade C, 21 with Grade D, and

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19

Sivapathasundharam, B., and S. Lavanya. "Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE)." Journal of Oral and Maxillofacial Pathology 9, no. 1 (2005): 30. http://dx.doi.org/10.4103/0973-029x.39058.

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20

Patel, K., V. Santhanam, and Ch Fowell. "Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE)." International Journal of Oral and Maxillofacial Surgery 48 (May 2019): 240. http://dx.doi.org/10.1016/j.ijom.2019.03.737.

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21

Astekar, Madhusudan, BhagirathiD Lakkam, Shakir Alam, and Adeeba Saleem. "Traumatic ulcerative granuloma with stromal eosinophilia: A puzzle." Journal of Oral and Maxillofacial Pathology 25, no. 4 (2021): 42. http://dx.doi.org/10.4103/jomfp.jomfp_321_20.

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22

CESAR, Ana Luiza Medeiros, Thiago Moreira PESSÔA, Marina Urquiza Lopes VIEIRA, et al. "TRAUMATIC GRANULOMA WITH TISSUE EOSINOPHILIA: A CASE REPORT." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 137, no. 6 (2024): e232. http://dx.doi.org/10.1016/j.oooo.2023.12.411.

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23

Subramanian, Shalini, Anand Krishnan, LahariA Telang, and Ajay Telang. "Traumatic ulcerative granuloma with stromal eosinophilia: Uncommon or misdiagnosed?" International Journal of Oral Health Sciences 11, no. 1 (2021): 64. http://dx.doi.org/10.4103/ijohs.ijohs_12_20.

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24

Nagaraj, Tejavathi, Durga Okade, Pooja Sinha, and I. P. Mahalakshmi. "Traumatic ulcerative granuloma with stromal eosinophilia: A diagnostic dilemma?" Journal of Advanced Clinical and Research Insights 1, no. 3 (2014): 102–5. http://dx.doi.org/10.15713/ins.jcri.26.

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25

Sidana, Sunil O., Shivaji R. Chavan, Padmakar S. Baviskar, and Srivalli Natarajan. "Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE): A rare pathology with unusual behavior." Journal of Oral and Maxillofacial Pathology 27, no. 3 (2023): 605–6. http://dx.doi.org/10.4103/jomfp.jomfp_524_22.

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Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion of oral mucosa with unclear pathogenesis. The etiology of TUGSE is still not clear, but traumatic irritation is considered to be the most likely cause. The lesion is usually self-limiting and regresses on its own or after biopsy and recurrence or reappearance of lesion is rare. We present a very unusual behavior of this lesion where lesion not only reappeared/recurred within few days of complete excision, but was larger than initial lesion and regressed after incisonal biopsy of the recurrent lesion. This prese

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26

Sarangarajan, R., VK Vaishnavi Vedam, G. Sivadas, Anuradha Sarangarajan, and S. Meera. "Traumatic ulcerative granuloma with stromal eosinophilia - Mystery of pathogenesis revisited." Journal of Pharmacy and Bioallied Sciences 7, no. 6 (2015): 420. http://dx.doi.org/10.4103/0975-7406.163474.

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27

Pereira, Treville, Subraj Shetty, and Svylvy Pereira. "Unusual presentation of a traumatic ulcerative granuloma with stromal eosinophilia." Journal of Orofacial Sciences 9, no. 1 (2017): 64. http://dx.doi.org/10.4103/0975-8844.207947.

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28

Shaikhi, Khaled, Ali M. Elmurtadi, and Mohammed Abdulrahim. "Horrific but Harmless, Traumatic Ulcerative Granuloma with Stromal Eosinophilia (Tugse)." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 119, no. 3 (2015): e165. http://dx.doi.org/10.1016/j.oooo.2014.07.279.

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29

Boffano, Paolo, Cesare Gallesio, Paola Campisi, and Fabio Roccia. "Traumatic Ulcerative Granuloma With Stromal Eosinophilia of the Retromolar Region." Journal of Craniofacial Surgery 20, no. 6 (2009): 2150–52. http://dx.doi.org/10.1097/scs.0b013e3181bec6f0.

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30

Babu, GSuresh, KPrudhvi Krishna, and NGovindraj Kumar. "Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) - A Case Report." SRM Journal of Research in Dental Sciences 3, no. 2 (2012): 163. http://dx.doi.org/10.4103/0976-433x.128070.

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31

Kaplan, I., A. Aizic, B. Shlomi, I. Solar, and V. Raiser. "ANALYSIS OF TRAUMATIC ULCERATIVE GRANULOMA WITH STROMAL EOSINOPHILIA: CD30 AND CLONALITY." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 122, no. 5 (2016): e170. http://dx.doi.org/10.1016/j.oooo.2016.06.069.

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32

Hullah, Esther, T. Kovacevic, and M. Escudier. "CR0307 Traumatic ulcerated granuloma with stromal eosinophilia associated with khat chewing." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 117, no. 5 (2014): e385-e386. http://dx.doi.org/10.1016/j.oooo.2014.01.205.

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33

Kuhl, Sebastian, RalfKurt Willy Schulze, Torsten Hansen, HansKonrad Muller-Hermelink, and Volker Hans-Ullrich. "Granuloma Riga-Fede (eosinophile traumatic ulcerative granuloma): A variant of a monoclonal CD30+ lymphoproliferative disorder." Journal of Oral and Maxillofacial Pathology 12, no. 1 (2008): 34. http://dx.doi.org/10.4103/0973-029x.42196.

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34

P S, Jayalakshmy, Jyothi C R, Prasad P H, and Kamala V V. "TRAUMATIC ULCERATIVE GRANULOMA WITH STROMAL EOSINOPHILIA - AN ORAL ULCER WITH SPECIFIC HISTOLOGY." Journal of Evolution of Medical and Dental Sciences 6, no. 02 (2017): 141–43. http://dx.doi.org/10.14260/jemds/2017/34.

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35

Fonsêca, Thamyres Campos, Maíra Tavares de Faria Cassab, Ana Maria Calderoni, et al. "Traumatic ulcerative granuloma with stromal eosinophilia: a series of 4 new cases." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 139, no. 5 (2025): e110. https://doi.org/10.1016/j.oooo.2025.01.548.

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36

Tobias, Renata Santos Fedato, Arthur Reymon Soares Oliveira, Stephany Pimenta Carvalho, Eneida Franco Vêncio, and Maria Alves Garcia Silva. "Traumatic ulcerative granuloma with stromal eosinophilia on the tongue: a case report." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 139, no. 5 (2025): e29. https://doi.org/10.1016/j.oooo.2025.01.151.

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37

Adesina, Olufunlola, Olujide Soyele, Adeola Ladeji, Kanmi Kuye, and Foluso Owotade. "Traumatic ulcerative granuloma with stromal eosinophilia: Review of the literature and case report." African Journal of Medical and Health Sciences 16, no. 2 (2017): 115. http://dx.doi.org/10.4103/ajmhs.ajmhs_8_17.

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38

Chatzistamou, Ioulia, Ipatia Doussis-Anagnostopoulou, George Georgiou, et al. "Traumatic Ulcerative Granuloma With Stromal Eosinophilia: Report of a Case and Literature Review." Journal of Oral and Maxillofacial Surgery 70, no. 2 (2012): 349–53. http://dx.doi.org/10.1016/j.joms.2011.03.026.

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39

Hirshberg, A., N. Amariglio, S. Akrish, R. Yahalom, H. Rosenbaum, and I. Kaplan. "T-cell Receptor Gene Rearrangement Analysis of Traumatic Ulcerative Granuloma With Stromal Eosinophilia." Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 103, no. 4 (2007): e19. http://dx.doi.org/10.1016/j.tripleo.2006.12.037.

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40

Shen, Wei-Ren, Julia Yu-Fong Chang, Yang-Che Wu, Shih-Jung Cheng, Hsin-Ming Chen, and Yi-Ping Wang. "Oral traumatic ulcerative granuloma with stromal eosinophilia: A clinicopathological study of 34 cases." Journal of the Formosan Medical Association 114, no. 9 (2015): 881–85. http://dx.doi.org/10.1016/j.jfma.2013.09.012.

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41

Setti, Giacomo, Stefania Caramaschi, Giuseppe Barile, et al. "Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate." Diagnostics 15, no. 2 (2025): 199. https://doi.org/10.3390/diagnostics15020199.

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Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion that may arise from the oral mucosa consisting in an ulcerative lesion usually localized in the tongue or cheek. Palate localization is very rare. Background/Objectives: The aim of this study is to describe a case of TUGSE occurring in the hard palate of an 83 y.o. female patient, manifesting as a non-painful growing palatal lesion approximately of 3.5 × 2 cm with firm consistency and a central area of erosion and erythema, the difficulties in clinical diagnosis, and the criteria for the differential diagnosis.

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42

Banerjee, Abhishek, Satya Ranjan Misra, Vivek Kumar, and Neeta Mohanty. "Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE): a rare self-healing oral mucosal lesion." BMJ Case Reports 14, no. 8 (2021): e245097. http://dx.doi.org/10.1136/bcr-2021-245097.

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43

KUMAR, Mathangi, Ravindranath VİNEETHA, Keerthilatha M PAİ, Abhay T KAMATH, and Chetana CHANDRASHEKAR. "Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE)-A Precursor of Oral Squamous Cell Carcinoma?" Cumhuriyet Dental Journal 23, no. 1 (2020): 67–70. http://dx.doi.org/10.7126/cumudj.648880.

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44

Phoorisriphong, N., C. Chinkrua, and A. Iamaroon. "A clinical study of traumatic ulcerative granuloma with stromal eosinophilia: review of eight cases." International Journal of Oral and Maxillofacial Surgery 46 (March 2017): 311. http://dx.doi.org/10.1016/j.ijom.2017.02.1049.

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45

León, JorgeEsquiche, BernardoFerreira Brasileiro, BrunoAugusto Benevenuto Andrade, DanielBerretta Alves, PabloAgustin Vargas, and OsleiPaes De Almeida. "Traumatic ulcerative granuloma with stromal eosinophilia of the palate showing an angiocentric/angiodestructive growth pattern." Contemporary Clinical Dentistry 3, no. 5 (2012): 109. http://dx.doi.org/10.4103/0976-237x.95118.

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46

Smith, Olivia, Olivia Smith, Vathana Ketheeswaranathan, and Michael Monteiro. "EP124 Differentiating Traumatic Ulcerative Granuloma with Stromal Eosinophilia from malignant conditions: Case series and literature review." British Journal of Oral and Maxillofacial Surgery 62, no. 10 (2024): e45. https://doi.org/10.1016/j.bjoms.2024.10.108.

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47

Eleni, Gagari, Stathopoulos Panagiotis, Katsambas Andreas, and Avgerinou Georgia. "Traumatic Ulcerative Granuloma With Stromal Eosinophilia: A Lesion With Alarming Histopathologic Presentation and Benign Clinical Course." American Journal of Dermatopathology 33, no. 2 (2011): 192–94. http://dx.doi.org/10.1097/dad.0b013e3181e26db0.

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48

Hannan, Tufayl Ahmed, Muhammed Umer, Labib Syed, and Mohamed Areeb Anis‐Alavi. "A case report of traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) in a 21‐year‐old." Clinical Case Reports 8, no. 11 (2020): 2214–16. http://dx.doi.org/10.1002/ccr3.3188.

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49

dos Reis, Andrea Candido, Jorge Esquiche León, Adriana Barbosa Ribeiro, Maria Paula Della Vecchia, Tatiana Ramirez Cunha, and Raphael Freitas de Souza. "Traumatic Ulcerative Granuloma with Stromal Eosinophilia around Mini Dental Implants without the Protection of a Denture Base." Journal of Prosthodontics 24, no. 1 (2014): 83–86. http://dx.doi.org/10.1111/jopr.12184.

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&NA;. "Traumatic Ulcerative Granuloma With Stromal Eosinophilia: A Lesion With Alarming Histopathologic Presentation and Benign Clinical Course: Erratum." American Journal of Dermatopathology 33, no. 8 (2011): 874. http://dx.doi.org/10.1097/dad.0b013e31823bf00d.

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