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Journal articles on the topic 'Treatment of recurrent hamstring strains'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

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1

Kilcoyne, Kelly G., Jonathan F. Dickens, David Keblish, John-Paul Rue, and Ray Chronister. "Outcome of Grade I and II Hamstring Injuries in Intercollegiate Athletes." Sports Health: A Multidisciplinary Approach 3, no. 6 (2011): 528–33. http://dx.doi.org/10.1177/1941738111422044.

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Background: Hamstring muscle strains represent a common and disabling athletic injury with variable recurrence rates and prolonged recovery times. Objectives: To present the outcomes of a novel rehabilitation protocol for the treatment of proximal hamstring strains in an intercollegiate sporting population and to determine any significant differences in the rate of reinjury and time to return to sport based on patient and injury characteristics. Study Design: Retrospective case series. Methods: A retrospective review was performed of 48 consecutive hamstring strains in intercollegiate athletes

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Manduca, Mary Lynn, and Stephen J. Straub. "Effectiveness of PRP Injection in Reducing Recovery Time of Acute Hamstring Injury: A Critically Appraised Topic." Journal of Sport Rehabilitation 27, no. 5 (2018): 480–84. http://dx.doi.org/10.1123/jsr.2016-0066.

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Clinical Scenario: Hamstring strains are common athletic injuries, with a high-recurrence rate (34%). Recently, platelet-rich plasma (PRP) injections have gained popularity as a potential treatment option to accelerate healing of hamstring injury. Focused Clinical Question: Does the combination of PRP injection and rehabilitation decrease recovery time of acute hamstring injury as compared to rehabilitation alone in college athletes? Summary of Key Findings: A literature search resulted in 3 randomized controlled trials. One study showed benefits in various outcome measures with PRP, compared

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Craddock, N., and K. Buchholtz. "Preventing the seemingly unpreventable – challenging the return-to-play criteria for recurrent hamstring strain prevention." South African Journal of Sports Medicine 30, no. 1 (2018): 1–2. http://dx.doi.org/10.17159/2078-516x/2018/v30i1a3401.

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 Background: Hamstring strains are one of the most common injuries in sport. Previous injury has been found to be one of the greatest risk factors associated with recurrent hamstring strains. Although rehabilitation programmes have been developed and implemented to aid safe and efficient return-to-play, the incidence of hamstring injuries has not decreased.  Discussion: As hamstring strains most commonly occur during the eccentric phase of muscle action, rehabilitation should focus on eccentric muscle strengthening. The L-protocol and the Nordic Hamstring Exercise protocol strength

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Khattak, Noman Ali, Yumna Ali, Rabiya Akbar, Fatima Khattak, and Sufana Ali. "Hamstring Injury Recurrence and Prevention: A Review." Life and Science 2, no. 3 (2021): 7. http://dx.doi.org/10.37185/lns.1.1.188.

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Football stands to be the most favorite sport with approximately four billion fans worldwide. Injuries in thegame can often be frustrating to the fans, athletes and the club, affecting performance and financialoperations. An avoidance curriculum to help cut down risks of such injuries seems obligatory, concerning thesocioeconomic and financial repercussions. An issue that is frequently discussed in sports medicine isHamstring Strain Injuries (HSI) that is widely seen amongst players which could prevent them from engaging inimportant games. HSI are one of the most frequently occurring injuries

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Okoroha, Kelechi R., Stan Conte, Eric C. Makhni, et al. "Hamstring Injury Trends in Major and Minor League Baseball: Epidemiological Findings From the Major League Baseball Health and Injury Tracking System." Orthopaedic Journal of Sports Medicine 7, no. 7 (2019): 232596711986106. http://dx.doi.org/10.1177/2325967119861064.

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Background: Hamstring strains are the most common injury for professional baseball players and can result in significant time on the disabled list. To date, no study has reported the current trends in hamstring strains in professional baseball. Hypothesis: Professional baseball players would have an increased incidence of hamstring strains from 2011 through 2016. Study Design: Descriptive epidemiology study. Methods: Injury data were prospectively collected from 2011 through 2016 for every Major League Baseball (MLB) and Minor League Baseball (MiLB) team and was recorded in the MLB Health and

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Clanton, Thomas O., and Kevin J. Coupe. "Hamstring Strains in Athletes: Diagnosis and Treatment." Journal of the American Academy of Orthopaedic Surgeons 6, no. 4 (1998): 237–48. http://dx.doi.org/10.5435/00124635-199807000-00005.

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7

Orchard, John W., Mohammad Chaker Jomaa, Jessica J. Orchard, et al. "Fifteen-week window for recurrent muscle strains in football: a prospective cohort of 3600 muscle strains over 23 years in professional Australian rules football." British Journal of Sports Medicine 54, no. 18 (2020): 1103–7. http://dx.doi.org/10.1136/bjsports-2019-100755.

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ObjectivesTo determine the rates of muscle strain injury recurrence over time after return to play in Australian football and to quantify risk factors.MethodsWe analysed Australian Football League player data from 1992 to 2014 for rates of the four major muscle strain injury types (hamstring, quadriceps, calf and groin) diagnosed by team health professionals. Covariates for analysis were: recent history (≤8 weeks) of each of the four muscle strains; non-recent history (>8 weeks) of each; history of hip, knee anterior cruciate ligament, knee cartilage, ankle sprain, concussion or lumbar inju

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8

Lempainen, Lasse, Jussi Kosola, Ricard Pruna, et al. "Central Tendon Injuries of Hamstring Muscles: Case Series of Operative Treatment." Orthopaedic Journal of Sports Medicine 6, no. 2 (2018): 232596711875599. http://dx.doi.org/10.1177/2325967118755992.

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Background: As compared with injuries involving muscle only, those involving the central hamstring tendon have a worse prognosis. Limited information is available regarding the surgical treatment of central tendon injuries of the hamstrings. Purpose: To describe the operative treatment and outcomes of central tendon injuries of the hamstrings among athletes. Study Design: Case series; Level of evidence, 4. Methods: Eight athletes (6 top level, 2 recreational) with central hamstring tendon injuries underwent magnetic resonance imaging and surgical treatment. The indication for surgery was recur

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Sherry, Marc A., Thomas M. Best, Amy Silder, Darryl G. Thelen, and Bryan C. Heiderscheit. "Hamstring Strains: Basic Science and Clinical Research Applications for Preventing the Recurrent Injury." Strength and Conditioning Journal 33, no. 3 (2011): 56–71. http://dx.doi.org/10.1519/ssc.0b013e31821e2f71.

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10

Koulouris, George, David A. Connell, Peter Brukner, and Michal Schneider-Kolsky. "Magnetic Resonance Imaging Parameters for Assessing Risk of Recurrent Hamstring Injuries in Elite Athletes." American Journal of Sports Medicine 35, no. 9 (2007): 1500–1506. http://dx.doi.org/10.1177/0363546507301258.

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Background Magnetic resonance (MR) imaging has established its usefulness in diagnosing hamstring muscle strain and identifying features correlating with the duration of rehabilitation in athletes; however, data are currently lacking that may predict which imaging parameters may be predictive of a repeat strain. Purpose This study was conducted to identify whether any MR imaging-identifiable parameters are predictive of athletes at risk of sustaining a recurrent hamstring strain in the same playing season. Study Design Cohort study; Level of evidence, 3. Methods Forty-one players of the Austra

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Sherry, Marc A., and Thomas M. Best. "A Comparison of 2 Rehabilitation Programs in the Treatment of Acute Hamstring Strains." Journal of Orthopaedic & Sports Physical Therapy 34, no. 3 (2004): 116–25. http://dx.doi.org/10.2519/jospt.2004.34.3.116.

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12

Bradley, James P., Tracye J. Lawyer, Sonia Ruef, Jeffrey D. Towers, and Justin W. Arner. "Platelet-Rich Plasma Shortens Return to Play in National Football League Players With Acute Hamstring Injuries." Orthopaedic Journal of Sports Medicine 8, no. 4 (2020): 232596712091173. http://dx.doi.org/10.1177/2325967120911731.

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Background: Hamstring injuries are prevalent in professional athletes and can lead to significant time loss, with recurrent injury being common. The efficacy of platelet-rich plasma (PRP) for augmentation of nonoperative treatment of partial musculotendinous hamstring injuries is not well established. Hypothesis: The addition of PRP injections to nonoperative treatment for acute partial musculotendinous hamstring injuries will lead to a shortened return to play in National Football League (NFL) players. Study Design: Cohort study; Level of evidence, 3. Methods: NFL players from a single team w

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Chang, Justin S., Babar Kayani, Ricci Plastow, Sandeep Singh, Ahmed Magan, and Fares S. Haddad. "Management of hamstring injuries: current concepts review." Bone & Joint Journal 102-B, no. 10 (2020): 1281–88. http://dx.doi.org/10.1302/0301-620x.102b10.bjj-2020-1210.r1.

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Injuries to the hamstring muscle complex are common in athletes, accounting for between 12% and 26% of all injuries sustained during sporting activities. Acute hamstring injuries often occur during sports that involve repetitive kicking or high-speed sprinting, such as American football, soccer, rugby, and athletics. They are also common in watersports, including waterskiing and surfing. Hamstring injuries can be career-threatening in elite athletes and are associated with an estimated risk of recurrence in between 14% and 63% of patients. The variability in prognosis and treatment of the diff

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Ronga, Mario, Francesco Oliva, Umile Giuseppe Longo, Vittorino Testa, Giovanni Capasso, and Nicola Maffulli. "Isolated Medial Patellofemoral Ligament Reconstruction for Recurrent Patellar Dislocation." American Journal of Sports Medicine 37, no. 9 (2009): 1735–42. http://dx.doi.org/10.1177/0363546509333482.

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Background Several medial patellofemoral ligament reconstruction procedures have been proposed to manage recurrent patellar dislocation. Hypothesis Reconstruction of the medial patellofemoral ligament using a hamstring graft with a 2 transverse patellar tunnels technique is an effective treatment for recurrent patellar dislocation in patients without any evident predisposing factors. Study Design Case series; Level of evidence, 4. Methods Twenty-eight patients with chronic patellar instability without any anatomic predisposing factors, experiencing recurrent unilateral patellar dislocation, we

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Kaeding, Christopher C., Kurt P. Spindler, Laura J. Huston, and Alex Zajichek. "ACL Reconstruction In High School and College-aged Athletes: Does Autograft Choice Affect Recurrent ACL Revision Rates?" Orthopaedic Journal of Sports Medicine 7, no. 7_suppl5 (2019): 2325967119S0028. http://dx.doi.org/10.1177/2325967119s00282.

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Objectives: Physicians’ and patients’ decision-making process between bone-patellar tendon-bone (BTB) versus hamstring autografts for ACL reconstruction (ACLR) may be influenced by a patient’s gender, laxity level, sport played, and/or competition level in the young, active athlete. The purpose of this study was to determine the incidence of subsequent ligament disruption for high school and college-aged athletes between autograft BTB versus hamstring grafts for ACLRs. Our hypothesis is there would be no recurrent ligament failure differences between autograft types at 6-year follow-up. Method

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Cross, Kevin M., Kelly K. Gurka, Susan Saliba, Mark Conaway, and Jay Hertel. "Comparison of Thigh Muscle Strain Occurrence and Injury Patterns Between Male and Female High School Soccer Athletes." Journal of Sport Rehabilitation 27, no. 5 (2018): 451–59. http://dx.doi.org/10.1123/jsr.2016-0178.

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Context: Thigh muscle strains are among the most common injuries in high school soccer for both males and females. Similar results have been reported among college soccer players, specifically for hamstring strains. In college soccer, males have a higher injury rate than women, although they share common injury characteristics. Currently, no studies exist comparing the injury rate or injury characteristics of thigh muscle strains between sexes playing high school soccer. Objective: To compare thigh muscle strain injury rates and injury event characteristics among sexes participating in high sc

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Englender, Moshe, Moshe Harell, Ruth Guttman, and Shmuel Segal. "Typing ofPseudomonas aeruginosaear infections related to outcome of treatment." Journal of Laryngology & Otology 104, no. 9 (1990): 678–81. http://dx.doi.org/10.1017/s002221510011360x.

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AbstractOf 142 patients withPseudomonas aeruginosa(PSA) ear infections, 88 (62 per cent) had chronic otitis media and 54 (38 per cent) external otitis. Following serotyping and pyocin typing of their bacteria, and relating the type to outcome, patients could be divided into three groups: (1) 120 patients who had no recurrence with isolation of only one PSA strain, (2) 13 patients who had recurrent infections and in whom the same PSA strain was isolated in repeated cultures, and (3) nine patients who had recurrent disease, but who had a change in their PSA strains. Most of the PSA strains isola

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Aguilar-Company, Juan, Ibai Los-Arcos, Carles Pigrau, et al. "Potential Use of Fosfomycin-Tromethamine for Treatment of Recurrent Campylobacter Species Enteritis." Antimicrobial Agents and Chemotherapy 60, no. 7 (2016): 4398–400. http://dx.doi.org/10.1128/aac.00447-16.

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ABSTRACTWe report 2 cases of recurrentCampylobacter colienteritis caused by macrolide- and fluoroquinolone-resistant strains in 2 patients with hypogammaglobulinemia, successfully treated with a prolonged course of fosfomycin-tromethamine with no side effects. Fosfomycin-tromethamine may be a feasible alternative therapy for recurrent enteritis caused byCampylobacterspecies resistant to first-line drugs.

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Herrington, Lee. "Patients with hamstring muscle strains returning to sport in less than 14 days: a case report of treatment used." Physical Therapy in Sport 1, no. 4 (2000): 137–38. http://dx.doi.org/10.1054/ptsp.2000.0021.

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Tarai, Bansidhar, Poonam Das, and Dilip Kumar. "Recurrent Challenges for Clinicians: Emergence of Methicillin-resistant Staphylococcus aureus, Vancomycin Resistance, and Current Treatment Options." Journal of Laboratory Physicians 5, no. 02 (2013): 071–78. http://dx.doi.org/10.4103/0974-2727.119843.

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ABSTRACTGram-positive pathogens mainly, Staphylococcus aureus, Enterococcus and coagulase-negative Staphylococcus, are developing increasing resistance to glycopeptides that pose a problem in treating infections caused by these pathogens. Vancomycin is the treatment of choice in treating methicillin-resistant S. aureus (MRSA). Community-acquired MRSA is associated with infections in patients without recent history of hospital admission and without the classical risk factors for MRSA carriage (including healthcare personnel). MRSA poses new threats and challenges beyond the hospital with the em

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Henatsch, Darius, Cindy H. Nabuurs, Rens M. van de Goor, Petra F. Wolffs, and Robert J. Stokroos. "Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study." Otolaryngology–Head and Neck Surgery 157, no. 4 (2017): 696–99. http://dx.doi.org/10.1177/0194599817718782.

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Eczematous external otitis is a chronic inflammatory disease and often difficult to treat. Our objective was to investigate the clinical effect and in vitro antibacterial potential of medical honey eardrops as treatment of eczematous external otitis. In a prospective study, 15 patients diagnosed with recurrent eczematous external otitis were treated with medical honey eardrops for 2 weeks. The following clinical outcomes were evaluated: visual analog scale of ear complaints, score of eczema, and eradication of bacterial infection. Furthermore, the antibacterial effect of honey eardrops against

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Ghosh, Sanjib, Ayon Das, Mahak Baid, and Arijit Das. "Medial patellofemoral ligament reconstruction using autologous hamstring graft for recurrent patellar dislocation: a clinical and functional outcome evaluation." International Journal of Research in Orthopaedics 7, no. 4 (2021): 854. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20212436.

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<p>Patellofemoral instability is a painful and often recurring disorder with many negative long-term consequences. Surgical treatment for patellar dislocation has evolved from the initial medial reefing to the present-day anatomical reconstruction of medial patellofemoral ligament (MPFL) which is thought to be the most appropriate treatment. MPFL reconstruction successfully addresses patellofemoral instability by restoring the deficient most important static primary soft tissue restraint. This prospective case series was conducted at a Tertiary care Govt. Hospital in Kolkata between Janu

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Gallant, Scott. "Assessing Adverse Neural Tension in Athletes." Journal of Sport Rehabilitation 7, no. 2 (1998): 128–39. http://dx.doi.org/10.1123/jsr.7.2.128.

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Sports medicine assessment and treatment techniques are ever developing and becoming more holistic. Traditional musculoskeletal assessment is changing to incorporate neural tissue pathology. Neural tension tests assess the mobility of neural tissue in the extremities and spinal canal. Positive adverse neural tension tests suggest poor mobility of neural tissue. Athletes with adverse neural tension often present with pain and decreased range of motion. These disorders can occur individually or can be associated with sports injuries. Ankle sprains, hamstring strains, tennis elbow, and thoracic o

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Norinder, Birgit Stattin, Ragnar Norrby, Ann-Chatrin Palmgren, Sofia Hollenberg, Ulla Eriksson, and Carl Erik Nord. "Microflora Changes with Norfloxacin and Pivmecillinam in Women with Recurrent Urinary Tract Infection." Antimicrobial Agents and Chemotherapy 50, no. 4 (2006): 1528–30. http://dx.doi.org/10.1128/aac.50.4.1528-1530.2006.

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ABSTRACT Similar changes in the periurethral and vaginal microflora were observed in 19 women with recurrent urinary tract infection following treatment with norfloxacin (NOR) or pivmecillinam (PIV). Escherichia coli strains were suppressed by both treatments. Staphylococcus spp. and enterococci colony counts increased following PIV treatment in the periurethral flora but remained stable with NOR.

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Molodczova, Valentina, Andrey Il`in, Nikita Kazakov, Andrey Litvinov, and Andrey Akopov. "Recurrent respiratory papillomatosis with malignant transformation." Problems in oncology 67, no. 2 (2021): 282–86. http://dx.doi.org/10.37469/0507-3758-2021-67-2-282-286.

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Recurrent respiratory papillomatosis (RRP) is a rare disease with an unpredictable course. The etiology is associated with the human papillomavirus (HPV). Malignant transformation of papillomas is extremely rare. Two clinical cases of RRP malignization are presented. In the first case, 22-year-old women with a long history of RRP and the lower respiratory tract lesions, squamous cell lung cancer developed. Second case - development of squamous cell carcinoma from the tracheal papilloma in a 35-year-old patient. Aggressive local endobronchial treatment was carried out; however, the progno

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Saito, Mitsumasa, Mizuo Hirose, Hirofumi Ichinose, Sharon Y. A. M. Villanueva, and Shin-ichi Yoshida. "Molecular analysis of Streptococcus pyogenes strains isolated from patients with recurrent pharyngitis after oral amoxicillin treatment." Journal of Medical Microbiology 67, no. 11 (2018): 1544–50. http://dx.doi.org/10.1099/jmm.0.000833.

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Silverman, Neil S., Margie Morgan, and W. S. Nichols. "Candida lusitaniaeas an Unusual Cause of Recurrent Vaginitis and its Successful Treatment With Intravaginal Boric Acid." Infectious Diseases in Obstetrics and Gynecology 9, no. 4 (2001): 245–47. http://dx.doi.org/10.1155/s1064744901000400.

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Increasing use of short-course antifungal therapies in patients with recurrent vulvovaginitis may enable the emergence of less-common, more resistant yeast strains as vaginal pathogens. We report the case of a patient with chronically symptomatic and repeatedly treated vaginal candidiasis whose infection was attributable toCandidalusitaniae, a previously unreported cause of candidal vaginitis .

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Bernstein, Joel M., Michael Belmont, Howard S. Faden, Diane Dryja, Frank Scannapieco, and Judy Wolf. "Interference of Nontypeable Haemophilus Influenzae and Moraxella Catarrhalis by Streptococcus Oralis in Adenoid Organ Culture: A Possible Strategy for the Treatment of the Otitis-Prone Child." Annals of Otology, Rhinology & Laryngology 111, no. 8 (2002): 696–700. http://dx.doi.org/10.1177/000348940211100807.

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The role of viridans group streptococci (Streptococcus oralis) in the prevention of colonization with nontypeable Haemophilus influenzae and Moraxella catarrhalis was investigated in an adenoid organ culture system. The adenoids from 100 patients who were undergoing adenoidectomy for either hypertrophy or recurrent otitis media were used. Streptococcus oralis Parker uniformly inhibited colonization with nontypeable H influenzae or M catarrhalis over a 24-hour period of incubation in adenoid organ culture. Streptococcus oralis Booth, a noninhibitory strain, did not significantly reduce coloniza

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Potron, Anais, Jean-Luc Mainardi, Isabelle Podglajen, Fabienne Meunier, Marie-José Sanson-le Pors, and Béatrice Berçot. "Recurrent infective endocarditis due to Aggregatibacter actinomycetemcomitans: reinfection or relapse?" Journal of Medical Microbiology 59, no. 12 (2010): 1524–26. http://dx.doi.org/10.1099/jmm.0.024380-0.

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Aggregatibacter actinomycetemcomitans is commonly part of the normal microflora of the human upper respiratory tract. It has been implicated in periodontal disease and various infections, particularly endocarditis. We report here what we believe to be the first case of recurrent infective endocarditis due to A. actinomycetemcomitans in a 44-year-old woman occurring 5 years after the initial episode. Genomic analysis proved that the strains were closely related. Despite efficient antibiotic treatment, surgery was necessary for recovery.

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Luceri, Francesco, Julien Roger, Pietro Simone Randelli, Sébastien Lustig, and Elvire Servien. "How Does Isolated Medial Patellofemoral Ligament Reconstruction Influence Patellar Height?" American Journal of Sports Medicine 48, no. 4 (2020): 895–900. http://dx.doi.org/10.1177/0363546520902132.

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Background: Reconstruction of the medial patellofemoral ligament (MPFL) is the gold standard treatment for recurrent patellar dislocation. Patella alta has been reported in about half of patients with recurrent patellofemoral instability. Hypothesis: MPFL reconstruction (MPFLr) has a beneficial role in the correction of patellar height in patients with mild patella alta (Caton-Deschamps index [CDI] between 1.20 and 1.40). Study Design: Case series; Level of evidence, 4. Methods: Skeletally mature patients, with no history of previous or concomitant knee surgical procedures, who underwent isola

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Song, Jae-Jun, Byung Don Lee, Koen Hyeong Lee, Jong Dae Lee, Young Joo Park, and Moo Kyun Park. "Changes in Antibiotic Resistance in Recurrent Pseudomonas Aeruginosa Infections of Chronic Suppurative Otitis Media." Ear, Nose & Throat Journal 95, no. 10-11 (2016): 446–51. http://dx.doi.org/10.1177/0145561316095010-1107.

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This study investigated the changes in antibiotic resistance in recurrent Pseudomonas aeruginosa infections in chronic suppurative otitis media (CSOM). Its aim was to provide a treatment strategy for P aeruginosa infections in CSOM for the prevention of multidrug resistance. A case-control study was conducted in tertiary teaching hospitals in Korea. The experimental group included patients with recurrent P aeruginosa infection who had relapsed within 2 months after the successful control of a previous P aeruginosa infection. The control group consisted of patients with a P aeruginosa infection

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Akinboyo, Ibukunoluwa C., Annie Voskertchian, Gezahegn Gorfu, et al. "Epidemiology and risk factors for recurrent Staphylococcus aureus colonization following active surveillance and decolonization in the NICU." Infection Control & Hospital Epidemiology 39, no. 11 (2018): 1334–39. http://dx.doi.org/10.1017/ice.2018.223.

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AbstractObjectivesTo examine neonatal risk factors associated with recurrent Staphylococcus aureus colonization and to determine the genetic relatedness of S. aureus strains cultured from neonates before and after decolonization.Study designSingle-center retrospective cohort study of neonates admitted to the neonatal intensive care unit (NICU) from April 2013 to December 2015, during which weekly nasal cultures from hospitalized NICU patients were routinely obtained for S. aureus surveillance.SettingJohns Hopkins Hospital’s 45-bed level IV NICU in Baltimore, Maryland.MethodsDemographics and cl

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Juang, Paul, and Jennifer S. Hardesty. "Role of Fidaxomicin for the Treatment of Clostridium difficile Infection." Journal of Pharmacy Practice 26, no. 5 (2013): 491–97. http://dx.doi.org/10.1177/0897190013499526.

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Clostridium difficile is a gram-negative, anaerobic, spore-forming emerging pathogen within health care systems and community-based populations that has a high associated morbidity and mortality as well as cost for the health care system. Recent studies reported high rates of recurrence thus a need for new pharmacological agents to treat C difficile infections (CDIs). Fidaxomicin is a novel macrocyclic antibiotic, originally isolated from fermentation broth of Dactylosporangium aurantiacum spp Hamdenensis, with selective spectrum, unique pharmacokinetic and pharmacodynamics profile, adverse ef

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Sharma, Priyanka, Kandasamy Nagarajan, and Bihu Panda. "Antimicrobial Peptidomimetics for Recurrent Septicemia Infections: In Vitro Study for Immuno Compromised Disease Target." Drug Research 68, no. 09 (2018): 499–503. http://dx.doi.org/10.1055/s-0043-119069.

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AbstractThe frequency of Bacillus subtilis infection such as pneumonia pan-opthalmitis, visceral abscess or musculoskeletal infection etc. complications following bacteremia, meningitis in children & the infection associated with majority of motor vehicle accidents associated with trauma & gun shoot injury. Antibiotics which appear especially useful in the treatment of Bacillus. infection are clindamycin and vancomycin to which vast majority of strains are susceptible in vitro. Our objective is to test the synthesized peptidomimetics with the efforts mainly directed towards the identif

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Danz, Hillary R., Sangun Lee, Susan P. Chapman-Bonofiglio, et al. "The Impact of Actotoxumab Treatment of Gnotobiotic Piglets Infected With Different Clostridium difficile Isogenic Mutants." Journal of Infectious Diseases 221, no. 2 (2019): 276–84. http://dx.doi.org/10.1093/infdis/jiz459.

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Abstract Nosocomial infections with Clostridium difficile are on the rise in the Unites States, attributed to emergence of antibiotic-resistant and hypervirulent strains associated with greater likelihood of recurrent infections. In addition to antibiotics, treatment with Merck anti-toxin B (TcdB) antibody bezlotoxumab is reported to reduce recurrent infections. However, treatment with anti-toxin A (TcdA) antibody actotoxumab was associated with dramatically increased disease severity and mortality rates in humans and gnotobiotic piglets. Using isogenic mutants of C. difficile strain NAPI/BI/0

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Lai, Mei-Yin, Jen-Fu Hsu, Shih-Ming Chu, et al. "Risk Factors and Outcomes of Recurrent Candidemia in Children: Relapse or Re-Infection?" Journal of Clinical Medicine 8, no. 1 (2019): 99. http://dx.doi.org/10.3390/jcm8010099.

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In this paper, our aim was to investigate the incidence, clinical characteristics, risk factors, and outcomes of recurrent candidemia in children. We retrospectively reviewed all children with candidemia from a medical center in Taiwan between 2004 and 2015. Two episodes of candidemia ≥30 days apart with clinical and microbiological resolution in the interim were defined as “late recurrence”, and those that had 8–29 days apart from previous episodes were defined as “early recurrence”. 45 patients (17.2%) had 57 episodes of recurrent candidemia, and 24 had 28 episodes of late recurrent candidem

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McCullough, Michael J., Karl V. Clemons, John H. McCusker, and David A. Stevens. "Species Identification and Virulence Attributes ofSaccharomyces boulardii (nom. inval.)." Journal of Clinical Microbiology 36, no. 9 (1998): 2613–17. http://dx.doi.org/10.1128/jcm.36.9.2613-2617.1998.

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Saccharomyces boulardii (nom. inval.) has been used for the treatment of several types of diarrhea. Recent studies have confirmed that S. boulardii is effective in the treatment of diarrhea, in particular chronic or recurrent diarrhea, and furthermore that it is a safe and well-tolerated treatment. The aim of the present study was to identify strains of S. boulardiito the species level and assess their virulence in established murine models. Three strains of S. boulardii were obtained from commercially available products in France and Italy. The three S. boulardii strains did not form spores u

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Fomin, O., N. Fomina, Yu Kordon, and J. Trofimenko. "Improving the methods of local treatment in case of aphthous lesions on the oral mucosa." Reports of Vinnytsia National Medical University 24, no. 1 (2020): 106–9. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(1)-19.

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Annotation. Contamination of the oral mucosa ulcers with opportunistic microorganisms aggravates the course of chronic recurrent aphthous stomatitis (HRAC). Topical medicines help to eliminate inflammation rapidly and induce fast epithelization of the mucous membrane defect in patients with HRAC. The aim of the work was to create curative composition recipe for the local therapy at HRAC, resulting to higher effectiveness of antimicrobial therapy and acceleration of healing. 43 patients with HRAC were examined. Samples from the lesions were inoculated blood agar and Sabouraud agar. The conventi

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Fomina, N., H. Sukmanska, Yu Kordon, and J. Trofimenko. "Improving the methods of local treatment in case of aphthous lesions on the oral mucosa." Reports of Vinnytsia National Medical University 24, no. 1 (2020): 143–46. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(1)-28.

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Annotation. Contamination of the oral mucosa ulcers with opportunistic microorganisms aggravates the course of chronic recurrent aphthous stomatitis (HRAC). Topical medicines help to eliminate inflammation rapidly and induce fast epithelization of the mucous membrane defect in patients with HRAC. The aim of the work was to create curative composition recipe for the local therapy at HRAC, resulting to higher effectiveness of antimicrobial therapy and acceleration of healing. 43 patients with HRAC were examined. Samples from the lesions were inoculated blood agar and Sabouraud agar. The conventi

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Singer, Georg, Karl Kashofer, Christoph Castellani, and Holger Till. "Hirschsprung’s Associated Enterocolitis (HAEC) Personalized Treatment with Probiotics Based on Gene Sequencing Analysis of the Fecal Microbiome." Case Reports in Pediatrics 2018 (October 14, 2018): 1–6. http://dx.doi.org/10.1155/2018/3292309.

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Approximately 40% of children with Hirschsprung’s disease (HD) suffer from Hirschsprung’s associated enterocolitis (HAEC) despite correct surgery. Disturbances of the intestinal microbiome may play a role. Treatment with probiotics based on individual analyses of the fecal microbiome has not been published for HD patients with recurrent HAEC yet. A boy with trisomy 21 received transanal pull-through at the age of 6 months for rectosigmoid HD. With four years, he suffered from recurrent episodes of HAEC. The fecal microbiome was measured during three healthy and three HAEC episodes by next-gene

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Bayazitova, L. T., O. F. Tupkina, T. A. Chazova, N. S. Konyshev, K. N. Syuzev, and G. Sh Isaeva. "Phage sensitivity profiles of a nasopharyngeal opportunistic pathogen in Streptococcus pneumoniae carrier children with recurrent respiratory infections." Kazan medical journal 101, no. 3 (2020): 330–36. http://dx.doi.org/10.17816/kmj2020-330.

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Aim. To study the nature of microbiota and estimating the susceptibility to antibiotics and bacteriophages of conditionally pathogenic microflora of the nasopharynx in children-pneumococcal carriers with recurrent respiratory infections. Methods. Researching microflora was conducted in 182 pneumococcal carriers receiving help in Kazan Scientific and Research Institute of Epidemiology and Microbiology. Microbial identification, testing of susceptibility to antibiotics and bacteriophages was carried out following the regulatory documentation. Bacterial isolates were confirmed by mass spect

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Tramer, Joseph S., Mohsin S. Fidai, Omar Kadri, et al. "Anterolateral Ligament Reconstruction Practice Patterns Across the United States." Orthopaedic Journal of Sports Medicine 6, no. 12 (2018): 232596711881106. http://dx.doi.org/10.1177/2325967118811063.

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Background: A proposed mechanism for recurrent instability following anterior cruciate ligament (ACL) reconstruction is failure of the anterolateral ligament (ALL). Presently, there are a number of approaches to treating ALL pathology. Purpose: To determine practice patterns among orthopaedic surgeons regarding ALL during ACL reconstruction. Study Design: Cross-sectional study. Methods: An online 7-question survey was sent to all physicians registered with the American Orthopaedic Society for Sports Medicine between June and July 2017. Results were analyzed with the survey website. Results: Ov

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Rentinck, Marc-Nicolas, Renate Krüger, Pia-Alice Hoppe, et al. "Skin infections due to Panton-Valentine leukocidin (PVL)-producing S. aureus—Cost effectiveness of outpatient treatment." PLOS ONE 16, no. 6 (2021): e0253633. http://dx.doi.org/10.1371/journal.pone.0253633.

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Introduction Skin and soft tissue infections (SSTI) caused by Panton-Valentine leukocidin (PVL)-producing strains of Staphylococcus aureus (PVL-SA) are associated with recurrent skin abscesses. Secondary prevention, in conjunction with primary treatment of the infection, focuses on topical decolonization. Topical decolonization is a standard procedure in cases of recurrent PVL-SA skin infections and is recommended in international guidelines. However, this outpatient treatment is often not fully reimbursed by health insurance providers, which may interfere with successful PVL-SA decolonization

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Lacheta, Lucca, Travis J. Dekker, Brandon T. Goldenberg, et al. "Minimum 5-Year Clinical Outcomes, Survivorship, and Return to Sports After Hamstring Tendon Autograft Reconstruction for Sternoclavicular Joint Instability." American Journal of Sports Medicine 48, no. 4 (2020): 939–46. http://dx.doi.org/10.1177/0363546519900896.

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Background: Instability of the sternoclavicular (SC) joint is a rare but potentially devastating pathologic condition, particularly when it occurs in young or active patients, where it can lead to persistent pain and impairment of shoulder function. SC joint reconstruction using a hamstring tendon autograft is a commonly used treatment option, but midterm results are still lacking. Purpose/Hypothesis: The purpose of this study was to assess the clinical outcomes, survivorship, and return-to-sports rate after SC joint reconstruction using a hamstring tendon autograft in patients suffering from

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Hicks, Nathan D., Samantha R. Giffen, Peter H. Culviner, et al. "Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis." PLOS Pathogens 16, no. 11 (2020): e1009063. http://dx.doi.org/10.1371/journal.ppat.1009063.

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Genomic dissection of antibiotic resistance in bacterial pathogens has largely focused on genetic changes conferring growth above a single critical concentration of drug. However, reduced susceptibility to antibiotics—even below this breakpoint—is associated with poor treatment outcomes in the clinic, including in tuberculosis. Clinical strains of Mycobacterium tuberculosis exhibit extensive quantitative variation in antibiotic susceptibility but the genetic basis behind this spectrum of drug susceptibility remains ill-defined. Through a genome wide association study, we show that non-synonymo

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Park, Jung Wee, Young-Kyun Lee, Yun Jong Lee, Seunghwan Shin, Yusuhn Kang, and Kyung-Hoi Koo. "Deep gluteal syndrome as a cause of posterior hip pain and sciatica-like pain." Bone & Joint Journal 102-B, no. 5 (2020): 556–67. http://dx.doi.org/10.1302/0301-620x.102b5.bjj-2019-1212.r1.

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Deep gluteal syndrome is an increasingly recognized disease entity, caused by compression of the sciatic or pudendal nerve due to non-discogenic pelvic lesions. It includes the piriformis syndrome, the gemelli-obturator internus syndrome, the ischiofemoral impingement syndrome, and the proximal hamstring syndrome. The concept of the deep gluteal syndrome extends our understanding of posterior hip pain due to nerve entrapment beyond the traditional model of the piriformis syndrome. Nevertheless, there has been terminological confusion and the deep gluteal syndrome has often been undiagnosed or

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Le Goaster, Jacqueline, Patrice Bouree, Franck N. El Sissy, et al. "HSV-1/HSV-2 Infection-Related Cancers in Bantu Populations Driving HIV-1 Prevalence in Africa: Tracking the Origin of AIDS at the Onset of the 20th Century." Case Reports in Oncology 9, no. 3 (2016): 815–25. http://dx.doi.org/10.1159/000450939.

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Introduction: At the onset of the 20th century, ancient clinical observations of cancer epidemics in Bantu populations of Sub-Saharan Africa were discovered. They were reported from 1914 to 1960, but remained unexplained. In 1983, in San Francisco, Calif., USA, cancer epidemics were related to infections by the human immunodeficiency virus type 1 (HIV-1) known as AIDS disease. Yet since 1996, it is known that HIV-1 strains are not the only ones involved. In Sub-Saharan Africa, recurrent orobuccal herpes simplex virus type 1 (HSV-1) and genital recurrent herpes simplex virus type 2 (HSV-2) appe

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Roberts, April, Joanna McGlashan, Ibrahim Al-Abdulla, et al. "Development and Evaluation of an Ovine Antibody-Based Platform for Treatment of Clostridium difficile Infection." Infection and Immunity 80, no. 2 (2011): 875–82. http://dx.doi.org/10.1128/iai.05684-11.

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ABSTRACTTreatment ofClostridium difficileis a major problem as a hospital-associated infection which can cause severe, recurrent diarrhea. The currently available antibiotics are not effective in all cases and alternative treatments are required. In the present study, an ovine antibody-based platform for passive immunotherapy ofC. difficileinfection is described. Antibodies with high toxin-neutralizing titers were generated againstC. difficiletoxins A and B and were shown to neutralize three sequence variants of these toxins (toxinotypes) which are prevalent in humanC. difficileinfection. Pass

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Franz, Renate, Steven L. Kelly, David C. Lamb, Diane E. Kelly, Markus Ruhnke, and Joachim Morschhäuser. "Multiple Molecular Mechanisms Contribute to a Stepwise Development of Fluconazole Resistance in Clinical Candida albicans Strains." Antimicrobial Agents and Chemotherapy 42, no. 12 (1998): 3065–72. http://dx.doi.org/10.1128/aac.42.12.3065.

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ABSTRACT From each of two AIDS patients with oropharyngeal candidiasis, fiveCandida albicans isolates from recurrent episodes of infection which became gradually resistant against fluconazole during antimycotic treatment were analyzed for molecular changes responsible for drug resistance. In both patients, a single C. albicans strain was responsible for the recurrent infections, but the CARE-2 fingerprint pattern of the isolates exhibited minor genetic alterations, indicating that microevolution of the strains took place during fluconazole therapy. In the isolates from patient 1, enhanced mRNA

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Ruiz-Pérez, Iñaki, Alejandro López-Valenciano, Alejandro Jiménez-Loaisa, Jose L. L. Elvira, Mark De Ste Croix, and Francisco Ayala. "Injury incidence, characteristics and burden among female sub-elite futsal players: a prospective study with three-year follow-up." PeerJ 7 (November 5, 2019): e7989. http://dx.doi.org/10.7717/peerj.7989.

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The main purpose of the current study was to analyze the injury incidence, characteristics and burden among sub-elite female futsal players. Individual exposure to match play and training, injury incidence and characteristics (player position, injury mechanism, type of injuries, severity of injuries, recurrent vs. new injuries, season variation of injury pattern) in a female futsal team were prospectively recorded for three consecutive seasons (2015–2018). Incidences were calculated per 1,000 h of exposure. A total of 30 injuries were reported during the three seasons within a total exposure o

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