Academic literature on the topic 'Treatment Planning System'

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Journal articles on the topic "Treatment Planning System"

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Guo, Fanqing. "3-D treatment planning system—Leksell Gamma Knife treatment planning system." Medical Dosimetry 43, no. 2 (2018): 177–83. http://dx.doi.org/10.1016/j.meddos.2018.03.001.

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Pellegrini, Roberto. "Plato Treatment Planning System." Tumori Journal 84, no. 2 (March 1998): 281–83. http://dx.doi.org/10.1177/030089169808400231.

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Sarkar, Vikren, Long Huang, Prema Rassiah-Szegedi, Hui Zhao, Jessica Huang, Martin Szegedi, and Bill J. Salter. "Planning for mARC treatments with the Eclipse treatment planning system." Journal of Applied Clinical Medical Physics 16, no. 2 (March 2015): 458–64. http://dx.doi.org/10.1120/jacmp.v16i2.5351.

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Xia, Ping, and Eric Murray. "3D treatment planning system—Pinnacle system." Medical Dosimetry 43, no. 2 (2018): 118–28. http://dx.doi.org/10.1016/j.meddos.2018.02.004.

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Abraham, David, Valdir Colussi, Donald Shina, Timothy Kinsella, and Claudio Sibata. "TBI treatment planning using the ADAC Pinnacle Treatment Planning System." Medical Dosimetry 25, no. 4 (December 2000): 219–24. http://dx.doi.org/10.1016/s0958-3947(00)00049-2.

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Santvoort, J. P. C. van. "Radiotherapy Treatment Planning: New System Approaches." Physics in Medicine and Biology 45, no. 12 (November 21, 2000): 3861. http://dx.doi.org/10.1088/0031-9155/45/12/702.

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Bodensteiner, Dayna. "RayStation: External beam treatment planning system." Medical Dosimetry 43, no. 2 (2018): 168–76. http://dx.doi.org/10.1016/j.meddos.2018.02.013.

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Schreuder, Andries N., Dan T. L. Jones, Julyan E. Symons, Evan A. De Kock, Jan K. Hough, Jenny Wilson, Fred J. A. Vernimmen, Wolfgang Schlegel, Angelika Höss, and Michael Lee. "The NAC proton treatment planning system." Strahlentherapie und Onkologie 175, S2 (June 1999): 10–12. http://dx.doi.org/10.1007/bf03038876.

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Purely, J. A., W. B. Harms, J. W. Wong, J. W. Matthews, E. D. Slessinger, and B. E. Emami. "Three-dimmsional radiation treatment planning system." International Journal of Radiation Oncology*Biology*Physics 12 (November 1986): 125–26. http://dx.doi.org/10.1016/0360-3016(86)90570-5.

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Lu, W., Q. Chen, M. Chen, Y. Chen, and G. Olivera. "Non-cluster TomoTherapy Treatment Planning System." International Journal of Radiation Oncology*Biology*Physics 78, no. 3 (November 2010): S741. http://dx.doi.org/10.1016/j.ijrobp.2010.07.1716.

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Dissertations / Theses on the topic "Treatment Planning System"

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Vader, Ranjeet D. "Development of computer aided heat treatment planning system (CAHTPS)." Link to electronic thesis, 2002. http://www.wpi.edu/Pubs/ETD/Available/etd-0830102-113605.

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Vaidya, Rohit Subhash. "Experimental testing of a computer aided heat treatment planning system." Link to electronic thesis, 2003. http://www.wpi.edu/Pubs/ETD/Available/etd-0827103-111212.

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Xian, Zheng. "Dose verification of a stereotactic IMRT treatment planning system." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/23810.

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In this project, ion chamber measurement and film dosimetry were used to verify dose distributions for a new stereotactic IMRT (Intensity Modulated Radiation Therapy) treatment planning system. This technique combines the principles of stereotactic radiosurgery and IMRT to significantly increase the positioning accuracy compared with conventional IMRT . Ion chamber measurements reveal that the discrepancy between the measured and the calculated dose at the isocenter can be up to 2%. Angular dependence of ion chamber sensitivity and the tissue equivalence of the phantom material were determined to be the main sources of this discrepancy. Radiochromic film was used as the film dosimeter in the project. A set of performance tests of Gafchromic EBT film indicated that the uncertainty in Gafchromic EBT film dosimety was expected to be 2.5%. However, the discrepancies we found in measurements of clinical cases using the film were much larger than this. And further investigation into this discrepancy was beyond the scope of this thesis.
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Mackin, Neil. "Development of an expert system for planning orthodontic treatment." Thesis, University of Bristol, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238890.

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Gardner, Joseph Kingsley. "Integration of VMC++ into a Commercial Treatment Planning System." VCU Scholars Compass, 2005. http://scholarscompass.vcu.edu/etd/990.

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Recently, there has been interest to integrate VMC++ into the commercial treatment planning system at VCU as another Monte Carlo code option, since it has been shown to increase efficiency dramatically without introducing a significant amount of systematic error. Also, independent validation of VMC++ for photon beams is of interest since this has not been performed previously in literature. This study included several tests required to integrate VMC++. Output factor normalization was performed and found to agree with experiment to within 1% for all field sizes except 1x1 cm2. Geometric validation was successful. Dosimetric validation was performed with respect to DOSXYZnrc on a water phantom, resulting in agreement within statistical uncertainty except for slight differences at the surface of the phantom. Dosimetric comparison was made for a head-and-neck patient case, showing that 5% of the voxels did not agree within 2.8% of maximum dose. The ability of VMC++ to compute dose-to-water was compared to an in-house algorithm and found to agree within statistical uncertainty.
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Mathayomchan, Boonyanit. "MULTIOBJECTIVE APPROACH TO MORPHOLOGICAL BASED RADIATION TREATMENT PLANNING." Case Western Reserve University School of Graduate Studies / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=case1131365356.

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Orfali, Anas. "Verification of a 3D external photon beam treatment planning system." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=24374.

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Treatment planning is recognized as a fundamental step in clinical radiotherapy. The increased availability and complexity of three dimensional (3D) computerized treatment planning systems necessitates a full verification protocol to be completed prior to the implementation of the treatment planning system in routine use.
We have designed and performed a detailed experimental verification program aimed at evaluating each individual dosimetric aspect of our 3D computerized treatment planning system (Varian CADPLAN, version 2.62). The verification tests ranged in complexity from the most basic standard geometry to a simulation of a full treatment case. Results from each individual testing geometry are presented, and an overall evaluation is discussed. We have concluded that our 3D treatment planning system is acceptable for clinical use.
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Obata, Yasunori, and Hiroshi Oguchi. "Commissioning of modulator-based IMRT with XiO treatment planning system." AIP Publishing, 2009. http://hdl.handle.net/2237/20613.

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Nill, Simeon. "Development and application of a multi-modality inverse treatment planning system." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963121413.

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Williams, C. Lesley. "A computer-based decision support system for orthodontic diagnosis and treatment planning." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq21223.pdf.

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Books on the topic "Treatment Planning System"

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Haas, Olivier C. L. Radiotherapy treatment planning: New system approaches. London: Springer, 1999.

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Haas, Olivier Cyrille Louis. Radiotherapy Treatment Planning: New System Approaches. London: Springer London, 1999.

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M, Mills Virginia, Cassidy John W, and Katz Douglas I, eds. Neurologic rehabilitation: A guide to diagnosis, prognosis, and treatment planning. Malden, Mass: Blackwell Science, 1997.

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Cooper, Gerry. Planning for an integrated and co-ordinated system of addiction services in Manitoulin-Sudbury: Discussion paper. Sudbury, Ont: Manitoulin-Sudbury District Health Council, 1985.

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Grace, A. M. Periodontal control: An effective system for diagnosis, selection, control and treatment planning in general practice. London: Quintessence, 1989.

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L, Vigdal Gerald, and Center for Substance Abuse Treatment (U.S.), eds. Planning for alcohol and other drug abuse treatment for adults in the criminal justice system. Rockville, MD: U.S. Dept. of Health and Human Services, Public Health Service, Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Treatment, 1995.

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Jongsma, Arthur E. Therascribe 4.0 user's guide: The treatment planning and clinical record management system for mental health professionals. New York: Wiley, 2001.

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Wang, Lilie. Evaluations of dose distribution calculations in a commercial radiation treatment planning system by Monte Carlo simulation. Sudbury, Ont: Laurentian University, School of Graduate Studies, 2005.

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Leslie, Lewis, and United States Air Force, eds. Effective treatment of logistics resource issues in the Air Force planning, programming, and budgeting system (PPBS) process. Santa Monica, CA: RAND, 2003.

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Carol, Steinfeld, ed. The composting toilet system book: A practical guide to choosing, planning and maintaining composting toilet systems, a water-saving, pollution-preventing alternative. Concord, Mass: The Center for Ecological Pollution Prevention, 1999.

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Book chapters on the topic "Treatment Planning System"

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Amestoy, William. "Treatment Planning and Treatment Planning System (TPS)." In Review of Medical Dosimetry, 221–303. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-13626-4_3.

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Tuncay, Orhan. "The Invisalign System." In Digital Planning and Custom Orthodontic Treatment, 69–79. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119087724.ch10.

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Park, Jeong-Hoon, Woong Cho, Kwang-Ho Cheong, Won-Gyun Jung, and Tae-Suk Suh. "Development of IMRT Treatment Planning System." In IFMBE Proceedings, 240–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03474-9_68.

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Mori, Yutaro, Takeji Sakae, Kenta Takada, and Hideyuki Takei. "Treatment Planning System for Proton Radiotherapy." In Proton Beam Radiotherapy, 113–25. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_10.

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Dahlin, H., P. Ekström, and B. Högström. "Treatment Management System: The Integrated Network Solution for Better Cancer Treatment." In Tumor Response Monitoring and Treatment Planning, 567–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-48681-4_93.

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Marinetto, E., V. García-Vázquez, J. A. Santos-Miranda, F. Calvo, M. Valdivieso, C. Illana, M. Desco, and J. Pascau. "Optical Tracking System Integration into IORT Treatment Planning System." In IFMBE Proceedings, 37–40. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-00846-2_9.

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Kang, Sei-Kwon, Taejin Hwang, Kwang-Ho Cheong, Soah Park, Me-Yeon Lee, Kyoung Ju Kim, Do Hoon Oh, and Hoonsik Bae. "Electron arc planning on the commercial radiation treatment planning system." In IFMBE Proceedings, 281–82. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03474-9_80.

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Wcisło, R., W. Dzwinel, P. Gosztyla, D. A. Yuen, and W. Czech. "Interactive Visualization Tool for Planning Cancer Treatment." In Lecture Notes in Earth System Sciences, 607–37. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-16405-7_38.

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Montelius, A., B. Jung, G. Rikner, A. Murman, and K. Russell. "Quality Assurance Tests of the TMS-Radix Treatment Planning System." In Tumor Response Monitoring and Treatment Planning, 523–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-48681-4_85.

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Świerniak, Andrzej, Marek Kimmel, Jaroslaw Smieja, Krzysztof Puszynski, and Krzysztof Psiuk-Maksymowicz. "Signaling Pathways Dynamics and Cancer Treatment." In System Engineering Approach to Planning Anticancer Therapies, 139–69. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-28095-0_5.

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Conference papers on the topic "Treatment Planning System"

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Cheng, Andrew Y. S., Sally S. Y. Chung, and John C. K. Kwok. "Expert system for neurosurgical treatment planning." In Electronic Imaging: Science & Technology, edited by Mark T. Bolas, Scott S. Fisher, and John O. Merritt. SPIE, 1996. http://dx.doi.org/10.1117/12.237436.

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Shalev, S., D. Viggars, P. Hahn, and M. Stewart. "Towards an expert system for treatment planning." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1988. http://dx.doi.org/10.1109/iembs.1988.95302.

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Sandell, Julia, Chang Chang, Jarod C. Finlay, and Timothy C. Zhu. "A treatment planning system for pleural PDT." In BiOS, edited by David H. Kessel. SPIE, 2010. http://dx.doi.org/10.1117/12.843044.

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Sebaaly, Anthony, Corinne Bassile, Tamara Akl, Georges Farha, Jad El Barouky, Fares Azoury, and Sandy Rihana. "Radiotherapy Treatment Planning System Simulation Lung Cancer Application." In 2018 IEEE International Multidisciplinary Conference on Engineering Technology (IMCET). IEEE, 2018. http://dx.doi.org/10.1109/imcet.2018.8603054.

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Selmani, I., and P. Malkaj. "The use of wedge in the treatment planning system." In 10th Jubilee International Conference of the Balkan Physical Union. Author(s), 2019. http://dx.doi.org/10.1063/1.5091380.

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Fenning, Matthew C., D. Q. Brown, and J. Donald Chapman. "Exploitation of interstitial brachytherapy techniques for photodynamic therapy--I. Treatment planning for interstitial photoexcitation therapy: a photodosimetry treatment planning system." In OE/LASE '94, edited by Thomas J. Dougherty. SPIE, 1994. http://dx.doi.org/10.1117/12.179976.

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Wee, William G., and Srinivas Krovvidy. "A knowledge based planning approach for waste water treatment system." In the third international conference. New York, New York, USA: ACM Press, 1990. http://dx.doi.org/10.1145/98894.99110.

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Hariri, Sanaz, and Alireza Kamali Asl. "Introducing a complementary treatment planning software for GZP6 brachytherapy system." In 2010 3rd International Conference on Biomedical Engineering and Informatics (BMEI). IEEE, 2010. http://dx.doi.org/10.1109/bmei.2010.5639376.

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Zihan Zhuo, Heng Wang, Zuhe Wu, Weiming Zhai, and Jintian Tang. "Three-dimensional image visualization methods for hyperthemia treatment planning system." In 2015 4th International Conference on Computer Science and Network Technology (ICCSNT). IEEE, 2015. http://dx.doi.org/10.1109/iccsnt.2015.7490743.

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Lu, Yukying, Shara Lee, Kim Khaw, and Ruxu Du. "A 360-degree Holographic Display System for Radiotherapy Treatment Planning." In CAD'15. CAD Solutions LLC, 2015. http://dx.doi.org/10.14733/cadconfp.2015.394-397.

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Reports on the topic "Treatment Planning System"

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Wheeler, F., D. Wessol, C. Atkinson, and D. Nigg. Human applications of the INEL patient treatment planning system. Office of Scientific and Technical Information (OSTI), November 1995. http://dx.doi.org/10.2172/421331.

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Schuring, D., H. Westendorp, E. Van der Bijl, G. Bol, W. Crijns, A. Delor, Y. Jourani, et al. NCS Report 35: Quality assurance of Treatment Planning Systems. Delft: NCS, July 2022. http://dx.doi.org/10.25030/ncs-035.

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FEDOTKINA, S. A., O. V. MUZALEVA, and E. V. KHUGAEVA. RETROSPECTIVE ANALYSIS OF THE USE OF TELEMEDICINE TECHNOLOGIES FOR THE PREVENTION, DIAGNOSIS AND TREATMENT OF HYPERTENSION. Science and Innovation Center Publishing House, 2021. http://dx.doi.org/10.12731/978-0-615-67320-2-4-22.

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Introduction. The economic losses associated with disability due to diseases of the circulatory system, as well as the costs of providing medical care to patients suffering from heart and vascular diseases, are increasing annually. The state preventive measures currently being carried out are of a delayed nature. The results of the medical examination of the population of the Russian Federation in recent years (2015-2019) indicate that the incidence of cardiovascular diseases, including hypertension, is at a fairly high level. In the middle of the last century, the Concept of risk factors for the development of chronic non-communicable diseases were formulated, in the structure of which cardiovascular diseases, including arterial hypertension, occupies one of the primary positions. The concept is based on the results of promising epidemiological studies, and, at present, is a methodological basis for planning and organizing primary prevention of cardiovascular diseases. The purpose of the study. Based on the analysis of literary sources (including foreign ones) containing experience in the use of telemedicine technologies, to assess their significance for the prevention, diagnosis and treatment of hypertension, as well as forecasting improvements in the quality of medical care when adapting to the use of clinical recommendations. Materials and methods. The article provides an analytical review of the use of modern telemedicine technologies in the prevention of hypertension. The results of the study and their discussion. The analysis of literary sources has shown that in the context of the progress of information and telecommunication technologies in the healthcare system, a fundamentally new direction has appeared in the organization and provision of medical care to the population - telemedicine, which will ensure the modern level of prevention, detection and treatment of chronic non-communicable diseases, and also determines positive medical, social and economic performance indicators. To date, updates in the legislative framework of the Russian Federation are aimed at ensuring that medical care with the use of telemedicine technologies is more widespread, taking into account the standards of medical care and clinical recommendations. Conclusion. Based on a review of literature sources, it has been established that the modern solution to the problem of improving the quality of medical care for patients, including those with hypertension, diseases is medical care using telemedicine technologies that prove their medical, social and economic effectiveness.
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Liekhus, K., J. Grandy, and A. Chambers. Partitioning planning studies: Preliminary evaluation of metal and radionuclide partitioning the high-temperature thermal treatment systems. Office of Scientific and Technical Information (OSTI), March 1997. http://dx.doi.org/10.2172/481852.

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Bruinvis, I. A. D., R. B. Keus, W. J. M. Lenglet, G. J. Meijer, B. J. Mijnheer, A. A. Van 't Veld, J. L. M. Venselaar, J. Welleweerd, and E. Woudstra. NCS Report 15: Quality assurance of 3-D treatment planning systems for external photon and electron beams. Delft: NCS, March 2005. http://dx.doi.org/10.25030/ncs-015.

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Huntington, Dale. Meeting women's health care needs after abortion. Population Council, 2000. http://dx.doi.org/10.31899/rh2000.1036.

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Women who seek emergency treatment for abortion complications—bleeding, infection, and injuries to the reproductive tract system—should be a priority group for reproductive health care programs. These women often receive poor-quality services that do not address their multiple health needs. They may be discharged without counseling on postoperative recuperation, family planning (FP), or other reproductive health (RH) issues. Women who have had an induced abortion due to an unwanted pregnancy are likely to have a repeat abortion unless they receive appropriate FP counseling and services. Preventing repeat unsafe abortions is important for RH programs because it saves women's lives, protects women’s health, and reduces the need for costly emergency services for abortion complications. At the 1994 International Conference on Population and Development, the world's governments called for improvements in postabortion medical services. As part of the resulting international postabortion care initiative, the Population Council’s Operations Research and Technical Assistance projects worked collaboratively to conduct research on interventions to improve postabortion care. This brief summarizes the major findings of this research and relevant studies by other international organizations.
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Meijer, G. J., H. J. Van Kleffens, and B. J. Mijnheer. NCS Report 11: Quality control (QC) of simulators and CT scanners and some basic QC methods for treatment planning systems. Delft: NCS, September 1997. http://dx.doi.org/10.25030/ncs-011.

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Rankin, Nicole, Deborah McGregor, Candice Donnelly, Bethany Van Dort, Richard De Abreu Lourenco, Anne Cust, and Emily Stone. Lung cancer screening using low-dose computed tomography for high risk populations: Investigating effectiveness and screening program implementation considerations: An Evidence Check rapid review brokered by the Sax Institute (www.saxinstitute.org.au) for the Cancer Institute NSW. The Sax Institute, October 2019. http://dx.doi.org/10.57022/clzt5093.

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Background Lung cancer is the number one cause of cancer death worldwide.(1) It is the fifth most commonly diagnosed cancer in Australia (12,741 cases diagnosed in 2018) and the leading cause of cancer death.(2) The number of years of potential life lost to lung cancer in Australia is estimated to be 58,450, similar to that of colorectal and breast cancer combined.(3) While tobacco control strategies are most effective for disease prevention in the general population, early detection via low dose computed tomography (LDCT) screening in high-risk populations is a viable option for detecting asymptomatic disease in current (13%) and former (24%) Australian smokers.(4) The purpose of this Evidence Check review is to identify and analyse existing and emerging evidence for LDCT lung cancer screening in high-risk individuals to guide future program and policy planning. Evidence Check questions This review aimed to address the following questions: 1. What is the evidence for the effectiveness of lung cancer screening for higher-risk individuals? 2. What is the evidence of potential harms from lung cancer screening for higher-risk individuals? 3. What are the main components of recent major lung cancer screening programs or trials? 4. What is the cost-effectiveness of lung cancer screening programs (include studies of cost–utility)? Summary of methods The authors searched the peer-reviewed literature across three databases (MEDLINE, PsycINFO and Embase) for existing systematic reviews and original studies published between 1 January 2009 and 8 August 2019. Fifteen systematic reviews (of which 8 were contemporary) and 64 original publications met the inclusion criteria set across the four questions. Key findings Question 1: What is the evidence for the effectiveness of lung cancer screening for higher-risk individuals? There is sufficient evidence from systematic reviews and meta-analyses of combined (pooled) data from screening trials (of high-risk individuals) to indicate that LDCT examination is clinically effective in reducing lung cancer mortality. In 2011, the landmark National Lung Cancer Screening Trial (NLST, a large-scale randomised controlled trial [RCT] conducted in the US) reported a 20% (95% CI 6.8% – 26.7%; P=0.004) relative reduction in mortality among long-term heavy smokers over three rounds of annual screening. High-risk eligibility criteria was defined as people aged 55–74 years with a smoking history of ≥30 pack-years (years in which a smoker has consumed 20-plus cigarettes each day) and, for former smokers, ≥30 pack-years and have quit within the past 15 years.(5) All-cause mortality was reduced by 6.7% (95% CI, 1.2% – 13.6%; P=0.02). Initial data from the second landmark RCT, the NEderlands-Leuvens Longkanker Screenings ONderzoek (known as the NELSON trial), have found an even greater reduction of 26% (95% CI, 9% – 41%) in lung cancer mortality, with full trial results yet to be published.(6, 7) Pooled analyses, including several smaller-scale European LDCT screening trials insufficiently powered in their own right, collectively demonstrate a statistically significant reduction in lung cancer mortality (RR 0.82, 95% CI 0.73–0.91).(8) Despite the reduction in all-cause mortality found in the NLST, pooled analyses of seven trials found no statistically significant difference in all-cause mortality (RR 0.95, 95% CI 0.90–1.00).(8) However, cancer-specific mortality is currently the most relevant outcome in cancer screening trials. These seven trials demonstrated a significantly greater proportion of early stage cancers in LDCT groups compared with controls (RR 2.08, 95% CI 1.43–3.03). Thus, when considering results across mortality outcomes and early stage cancers diagnosed, LDCT screening is considered to be clinically effective. Question 2: What is the evidence of potential harms from lung cancer screening for higher-risk individuals? The harms of LDCT lung cancer screening include false positive tests and the consequences of unnecessary invasive follow-up procedures for conditions that are eventually diagnosed as benign. While LDCT screening leads to an increased frequency of invasive procedures, it does not result in greater mortality soon after an invasive procedure (in trial settings when compared with the control arm).(8) Overdiagnosis, exposure to radiation, psychological distress and an impact on quality of life are other known harms. Systematic review evidence indicates the benefits of LDCT screening are likely to outweigh the harms. The potential harms are likely to be reduced as refinements are made to LDCT screening protocols through: i) the application of risk predication models (e.g. the PLCOm2012), which enable a more accurate selection of the high-risk population through the use of specific criteria (beyond age and smoking history); ii) the use of nodule management algorithms (e.g. Lung-RADS, PanCan), which assist in the diagnostic evaluation of screen-detected nodules and cancers (e.g. more precise volumetric assessment of nodules); and, iii) more judicious selection of patients for invasive procedures. Recent evidence suggests a positive LDCT result may transiently increase psychological distress but does not have long-term adverse effects on psychological distress or health-related quality of life (HRQoL). With regards to smoking cessation, there is no evidence to suggest screening participation invokes a false sense of assurance in smokers, nor a reduction in motivation to quit. The NELSON and Danish trials found no difference in smoking cessation rates between LDCT screening and control groups. Higher net cessation rates, compared with general population, suggest those who participate in screening trials may already be motivated to quit. Question 3: What are the main components of recent major lung cancer screening programs or trials? There are no systematic reviews that capture the main components of recent major lung cancer screening trials and programs. We extracted evidence from original studies and clinical guidance documents and organised this into key groups to form a concise set of components for potential implementation of a national lung cancer screening program in Australia: 1. Identifying the high-risk population: recruitment, eligibility, selection and referral 2. Educating the public, people at high risk and healthcare providers; this includes creating awareness of lung cancer, the benefits and harms of LDCT screening, and shared decision-making 3. Components necessary for health services to deliver a screening program: a. Planning phase: e.g. human resources to coordinate the program, electronic data systems that integrate medical records information and link to an established national registry b. Implementation phase: e.g. human and technological resources required to conduct LDCT examinations, interpretation of reports and communication of results to participants c. Monitoring and evaluation phase: e.g. monitoring outcomes across patients, radiological reporting, compliance with established standards and a quality assurance program 4. Data reporting and research, e.g. audit and feedback to multidisciplinary teams, reporting outcomes to enhance international research into LDCT screening 5. Incorporation of smoking cessation interventions, e.g. specific programs designed for LDCT screening or referral to existing community or hospital-based services that deliver cessation interventions. Most original studies are single-institution evaluations that contain descriptive data about the processes required to establish and implement a high-risk population-based screening program. Across all studies there is a consistent message as to the challenges and complexities of establishing LDCT screening programs to attract people at high risk who will receive the greatest benefits from participation. With regards to smoking cessation, evidence from one systematic review indicates the optimal strategy for incorporating smoking cessation interventions into a LDCT screening program is unclear. There is widespread agreement that LDCT screening attendance presents a ‘teachable moment’ for cessation advice, especially among those people who receive a positive scan result. Smoking cessation is an area of significant research investment; for instance, eight US-based clinical trials are now underway that aim to address how best to design and deliver cessation programs within large-scale LDCT screening programs.(9) Question 4: What is the cost-effectiveness of lung cancer screening programs (include studies of cost–utility)? Assessing the value or cost-effectiveness of LDCT screening involves a complex interplay of factors including data on effectiveness and costs, and institutional context. A key input is data about the effectiveness of potential and current screening programs with respect to case detection, and the likely outcomes of treating those cases sooner (in the presence of LDCT screening) as opposed to later (in the absence of LDCT screening). Evidence about the cost-effectiveness of LDCT screening programs has been summarised in two systematic reviews. We identified a further 13 studies—five modelling studies, one discrete choice experiment and seven articles—that used a variety of methods to assess cost-effectiveness. Three modelling studies indicated LDCT screening was cost-effective in the settings of the US and Europe. Two studies—one from Australia and one from New Zealand—reported LDCT screening would not be cost-effective using NLST-like protocols. We anticipate that, following the full publication of the NELSON trial, cost-effectiveness studies will likely be updated with new data that reduce uncertainty about factors that influence modelling outcomes, including the findings of indeterminate nodules. Gaps in the evidence There is a large and accessible body of evidence as to the effectiveness (Q1) and harms (Q2) of LDCT screening for lung cancer. Nevertheless, there are significant gaps in the evidence about the program components that are required to implement an effective LDCT screening program (Q3). Questions about LDCT screening acceptability and feasibility were not explicitly included in the scope. However, as the evidence is based primarily on US programs and UK pilot studies, the relevance to the local setting requires careful consideration. The Queensland Lung Cancer Screening Study provides feasibility data about clinical aspects of LDCT screening but little about program design. The International Lung Screening Trial is still in the recruitment phase and findings are not yet available for inclusion in this Evidence Check. The Australian Population Based Screening Framework was developed to “inform decision-makers on the key issues to be considered when assessing potential screening programs in Australia”.(10) As the Framework is specific to population-based, rather than high-risk, screening programs, there is a lack of clarity about transferability of criteria. However, the Framework criteria do stipulate that a screening program must be acceptable to “important subgroups such as target participants who are from culturally and linguistically diverse backgrounds, Aboriginal and Torres Strait Islander people, people from disadvantaged groups and people with a disability”.(10) An extensive search of the literature highlighted that there is very little information about the acceptability of LDCT screening to these population groups in Australia. Yet they are part of the high-risk population.(10) There are also considerable gaps in the evidence about the cost-effectiveness of LDCT screening in different settings, including Australia. The evidence base in this area is rapidly evolving and is likely to include new data from the NELSON trial and incorporate data about the costs of targeted- and immuno-therapies as these treatments become more widely available in Australia.
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9

Bolivia and Mexico: System-wide planning is needed for decentralized postabortion care. Population Council, 2005. http://dx.doi.org/10.31899/rh16.1000.

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Abstract:
Governments in developing countries recognize the need for appropriate technology for the treatment of emergencies from incomplete abortion or miscarriage. Numerous studies have investigated the appropriateness of an integrated model of postabortion care (PAC) that includes three essential elements: emergency treatment for spontaneous or induced abortion; counseling and family planning services; and links to other reproductive health services. Many integrated PAC services include replacement of the conventional clinical treatment, sharp curettage (SC), with manual vacuum aspiration (MVA). In 1997 and 1999 the Population Council supported intervention studies in Mexico and Bolivia, respectively, to assess PAC programs in terms of safety, effectiveness, quality of care, cost, and subsequent contraceptive use by clients. Both interventions introduced integrated PAC services and compared the outcomes of MVA and SC use in large public hospitals. To assess changes in service quality and costs, researchers analyzed clinical records and interviewed clients and providers before and after the interventions. As noted in this summary, SC and MVA are equally safe and effective and can be provided on an outpatient basis. Integrating clinical treatment with family planning counseling and services increased clients’ knowledge and contraceptive use.
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10

Integration of reproductive health service for men in health and family welfare centers in Bangladesh. Population Council, 2003. http://dx.doi.org/10.31899/rh2003.1002.

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Abstract:
Over the last 30 years, Bangladesh’s national family planning (FP) program has mainly concentrated its promotional efforts on women’s adoption of FP. While the government policy has been effective in influencing women to accept contraceptive methods, men’s role in FP has been completely neglected. Similarly, male RH services are hardly available at Health and Family Welfare Centres (HFWCs). This report describes a project aimed at integrating male RH services within the existing government female-focused health-care-delivery system. The study was implemented by NIPORT in collaboration with the Directorate of Family Planning and the Population Council. Interventions resulted in a substantial rise of male clients in the clinics, however nearly all came for the treatment of general health problems. Only a small number of male RTI/STI clients sought services from the clinics. Although unexpected, there was a substantial rise in the number of female clients. The study concluded that RH services for men could be easily integrated into HFWCs without affecting the female and child focus of the clinics and that augmentation of the total number of patients at HFWCs will lead to more effective use of resources and decreased cost of treatment.
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