Academic literature on the topic 'Treponematoses'

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Journal articles on the topic "Treponematoses"

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Goyal, S., KK Singal, and B. Singh. "Gummatous ulcer of leg: an uncommon entity in present era." Bangladesh Journal of Medical Science 10, no. 3 (August 15, 2011): 209–10. http://dx.doi.org/10.3329/bjms.v10i3.7514.

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Gummatous ulcer due to Treponematoses is quite rare in present era of potent antibiotics, increased social awareness and due to improvement in living standards of society .Better hygiene and improved medical care have contributed to containment of late benign syphilis or gummas. However, pockets of endemic treponematoses is still persisting in the underdeveloped, third world countries.Key words: Gummatous ulcer, treponematoses, antibiotics.DOI: http://dx.doi.org/10.3329/bjms.v10i3.7514BJMS 2011; 10(3): 209-210
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Engelkens, Herman Jan H., Jubianto Judanarso, Arnold P. Oranje, Vojislav D. Vuzevski, Paul L. A. Niemel, Jaap J. Sluis, and Ernst Stolz. "Endemic Treponematoses." International Journal of Dermatology 30, no. 2 (February 1991): 77–83. http://dx.doi.org/10.1111/j.1365-4362.1991.tb04215.x.

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Engelkens, Herman Jan H., Paul L. A. Niemel, Jaap J. Sluis, André Meheus, and Ernst Stolz. "Endemic Treponematoses." International Journal of Dermatology 30, no. 4 (April 1991): 231–38. http://dx.doi.org/10.1111/j.1365-4362.1991.tb04626.x.

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de Schryver, Antoon, and Andre Meheus. "Le Nouveau Visage D’une Vieille Maladie." Afrika Focus 4, no. 3-4 (January 15, 1988): 101–18. http://dx.doi.org/10.1163/2031356x-0040304003.

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New Aspects of an Old Disease. Pian, Endemic Syphilis and Pinta: The Endemic Treponematoses Yaws and the other endemic treponematoses (bejel or endemic syphilis, pinta) are resurging in many countries of Africa. Today there are more than 2.5 million cases of these diseases, 75% of them in children. More than 100 million additional children are at risk to these disabling and disfiguring infections which destroy tissue and bone. In the 1950’s and 1960’s, through concerted efforts and leadership of UNICEF and WHO, more than 50 million individuals in 46 countries were cured and the diseases were brought under control or even eliminated from large parts of the world. Despite this success, endemic foci remained and in the last ten years there has been an alarming resurgence of the endemic treponematoses, in particular in parts of West and Central Africa. Endemic treponematoses control is based on treatment with single-dose penicillin of the entire treponemal reservoir, and of all clinical cases and their contacts presumed to be incubating the disease. No instances of penicillin-resistance have been documented to date and these infections should be eliminated while the organisms still remain sensitive to penicillin. An endemic treponematoses control programme must be fully integrated into the primary health care system. The persistence of endemic treponematoses in an area is an indicator of failing effectiveness of primary health care. From recent consultations with Member States, WHO Collaborating Centres and expert groups, a consensus regarding the fundamental components of endemic treponematoses control has emerged. Effective disease control requires coordinated and complementary activities by WHO and Member States. The interruption of disease transmission is a feasible and realistic objective for renewed control programmes.
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Giacani, L., and S. A. Lukehart. "The Endemic Treponematoses." Clinical Microbiology Reviews 27, no. 1 (January 1, 2014): 89–115. http://dx.doi.org/10.1128/cmr.00070-13.

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Meheus, André. "Non-venereal treponematoses." Medicine 33, no. 10 (October 2005): 82–84. http://dx.doi.org/10.1383/medc.2005.33.10.82.

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Meheus, Andre. "Non-venereal Treponematoses." Medicine 29, no. 8 (August 2001): 78–81. http://dx.doi.org/10.1383/medc.29.8.78.28397.

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Antal, Georg Michael, Sheila A. Lukehart, and André Z. Meheus. "The endemic treponematoses." Microbes and Infection 4, no. 1 (January 2002): 83–94. http://dx.doi.org/10.1016/s1286-4579(01)01513-1.

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Jung, Rodney C. "Handbook of Endemic Treponematoses." American Journal of Tropical Medicine and Hygiene 34, no. 6 (November 1, 1985): 1234. http://dx.doi.org/10.4269/ajtmh.1985.34.1234.

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Rothschild, B. M. "Treponematoses and the New World." American Journal of Roentgenology 173, no. 4 (October 1999): 1133–34. http://dx.doi.org/10.2214/ajr.173.4.10511198.

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Dissertations / Theses on the topic "Treponematoses"

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Filippini, José. "Treponematoses e outras paleopatologias em sítios arqueológicos pré-históricos do litoral sul e sudeste do Brasil." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-17072012-091307/.

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Embora estudadas há décadas, a origem e dispersão de treponematoses permanecem como questões das mais acirradamente discutidas. No intuito de enriquecer esta discussão, a presente tese avalia sistematicamente 45 coleções osteológicas de populações costeiras do sul-sudeste do Brasil datadas entre 5000 anos AP e 1500 AD. Foram combinadas três metodologias numa abordagem conservadora para estabelecer o diagnóstico diferencial entre sífilis venérea, congênita, endêmica (bejel) e framboesia (yaws). Dentre os 768 indivíduos estudados foram encontrados 22 casos suspeitos de treponematose, inclusive com lesões tipo Caries sicca e tíbia em forma de sabre (sinais patognomônicos). A frequência geral resultante (22/768=2,86%) é certamente uma subestimativa. Houve 4 casos claros de sífilis venérea e 9 de framboesia, sendo os demais inconclusivos. Não foi observado nenhum caso claro de bejel e nos sítios com mais de um tipo suspeito, os diagnósticos eram iguais ou inconclusivos. Não houve tampouco um padrão geográfico ou temporal claro na distribuição dos casos de treponematose. Algumas outras paleopatologias (Cribra orbitalia, hiperostose porotica, periostite e osteomielite) foram estudadas no intuito de testar se os grupos acometidos por treponematose apresentam maior estresse fisiológico. Esta hipótese foi confirmada; embora as causas para maior susceptibilidade à estresse fisiológico e treponematoses em alguns sítios em comparação com outros permaneçam em aberto. Algumas tendências temporais foram observadas, porém necessitam de confirmação. Ao longo dos milênios parece ter havido uma frequência decrescente de Cribra orbitalia, osteomielite, periostite e remodelação óssea. Por outro lado, parece ter havido uma frequência crescente nos aumentos de porosidades cranianas (Hiperostose porótica, porosidade serpentinosa craniana) e de treponematoses de 5000 anos AP a 1500 AD. Se os diagnósticos aqui apresentados forem confirmados, corrobora-se a hipótese pré-Colombiana. Por outro lado, a hipótese Colombiana da origem da sífilis há somente 500 anos, assim como a Unitária (de acordo com a qual a treponematose é uma doença com manifestações moduladas por fatores climáticos e bioculturais) não explicariam a distribuição das treponematoses aqui encontradas.
Although studied for decades, origin and dispersal of treponemal diseases remain one of the most discussed issues in paleopathology. Aiming to enrich this discussion, the present study systematically evaluates 45 osteological collections from coastal groups aged 5000 BP to 1500 AD, exumed from sites in south-southeastern Brazil. Three different methods were combined and used in a conservative approach to establish differential diagnosis between venereal syphilis, yaws and bejel. Amongst the 768 individuals studied there are 22 cases with possible treponematosis, including some with Caries sicca and saber shin tibiae (patognomonic signs). The final frequency (22/768=2,86%) is certainly an underestimation. There are 4 cases affected with venereal syphilis and 9 with yaws. The remaining 9 cases are inconclusive. No clear case of bejel was found and in those sites were more than one individual was affected, the diagnoses were either the same or were inconclusive. No clear temporal nor geographic pattern of distribution was found. Some other paleopathologies were also studied (cribra orbitalia, porotic hyperostosis, periostitis and osteomyelite) in order to test if those groups affected with treponematoses also showed more physiological stress. Although this hypothesis was confirmed, the reasons that some groups were more susceptible to physiologial stress and treponemal diseases than other remains open. Some temporal tendencies were observed but need confirmation. There seems to have been a decrease in frequency of cribra orbitalia, osteomyelitis, periostitis and bone remodellling across time. On the other hand, there is also a upward shift in the frequency of porotic hyperostosis and treponematoses from 5000BP to 1500AD. If the candidate cases presented here would be confirmed, the pre-Columbian hypothesis seems more plausible. On the other hand, the Columbian hypothesis on the recent origin of syphilis, as well as the Unitarian hypothesis (according to which treponematosis is one disease with clinical manifestations influenced by climatic as well as bio-cultural factors) does not explain the distribution of treponematoses found herein.
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Wilson, Diane Elizabeth. "The paleoepidemiology of treponematosis in Texas /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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Hunnius, Tanya von Saunders S. R. "Applying skeletal, histological and molecular techniques to syphilitic skeletal remains from the past /." *McMaster only, 2004.

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Mercier, Helen Ceclie. "Investigation of the neutralizing activity for Treponema Pallidum of neonatal rabbit basal serum taken at 2, 3, and 4 weeks of age." CSUSB ScholarWorks, 1987. https://scholarworks.lib.csusb.edu/etd-project/397.

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Vradenburg, Joseph A. "The role of treponematoses in the development of prehistoric cultures and the bioarchaeology of proto-urbanism on the central coast of Peru /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3025658.

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CASTRO, Rita Maria Rodrigues Teixeira de. "Contribuição para o estudo de infecção por Treponema pallidum subespécie pallidum: resposta serológica, diagnóstico molecular e genotipagem." Doctoral thesis, Instituto de Higiene e Medicina Tropical, 2004. http://hdl.handle.net/10362/56799.

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A sífilis é uma doença sexualmente transmitida, reconhecida como tal desde o século XVI, cujo agente etiológico é Treponema pallidum subespécie pallidum, para o qual não existe meio de cultura artificial. Sendo uma infecção com inúmeras manifestações clínicas, incluindo a fase de latência e não havendo uma técnica que possa ser um verdadeiro teste padrão, o seu diagnóstico clínico e laboratorial afigura-se muitas vezes difícil. Nesta tese foram avaliados vários testes Venereal Disease Research Laboratory (VDRL), Rapid Plasma Reagin Test (RPR), Treponema pallidum Hemaglutination Antibody (TPHA), Fluorescent Treponemal Antibody Absortion (FTA-Abs), Passive Particle Agglutination Test (TP.PA), teste imunoenzimática (SYPHILIS-EIA) e Western-blot para a pesquisa de anticorpos anti-Treponema pallidum e técnicas de biologia molecular reacção em cadeia da polimerase (PCR) para o diagnóstico da sífilis nos seus diferentes estádios, incluindo neurossífilis. Experimentaram-se várias sequências iniciadoras (47-F/47-R, polA-F/polA-R-(PE), KO3A/KO4 e polA-F/polA-R) para amplificação de fragmentos dos genes da lipoproteína de 47kDa e do ADN polimerase I, e diferentes tipos de amostras: exsudado de úlceras genitais e de lesões cutâneas de secundarismo, exsudado de biopsias do lóbulo da orelha, sangue total, plasma, soro e liquor. Foram também optimizadas técnicas de PCR para a genotipagem de Treponema pallidum (amplificação de um fragmento do gene tpr e do gene arp) as quais foram aplicadas em algumas amostras incluídas neste estudo. Com a técnica de RPR obtiveram-se resultados idênticos ao VDRL no sangue e no liquor, pelo que parece que ambas as técnicas podem ser indiscriminadamente utilizadas nos dois tipos de produtos. Com os testes treponémicos obtiveram-se também, resultados semelhantes no liquor e no sangue. No entanto, as diferenças encontradas indicam que: a) o FTA-Abs, o Western-blot e o TP.PA devem ser os testes a utilizar nas fases precoces da infecção; b) o teste EIA parece indicado no caso de um grande número de amostras; c) o TP.PA e o TPHA podem ser utilizados na rotina laboratorial e, o primeiro eventualmente, também, na monitorização da terapêutica; d) o FTA-Abs e o Western-blot são os testes treponémicos que, de preferência devem ser utilizados no diagnóstico de neurossífilis embora os resultados do TP.PA se comparem aos do TPHA, no caso da infecção do sistema nervoso central por Treponema pallidum. A co-infecção com o VIH parece, ter efeito apenas, na reactividade dos testes não treponémicos, ocasionando falsa reactividade, independentemente da existência simultânea de toxicodependência. Em relação à técnica de PCR para o diagnóstico de sífilis, e para as várias sequências iniciadoras experimentadas os melhores resultados obtiveram-se com o par KO3A/KO4. A sensibilidade da técnica de PCR e de genotipagem nas amostras das úlceras genitais e das lesões cutâneas de sífilis secundária foi de 100%, o mesmo não acontecendo quando as técnicas se aplicaram à identificação de Treponema pallidum no sangue e no liquor, pelo que a técnica de PCR aplicada a este tipo de amostras necessita de ser aperfeiçoada. No entanto o exsudado de biopsia do lóbulo da orelha, seguida do plasma são os produtos, em que mais vezes, se identificou ADN de Treponema pallidum. O genótipo de Treponema pallidum subespécie pallidum mais frequentemente encontrado foi o 14c, sendo que o genótipo 10a foi pela primeira vez identificado no presente estudo.
Syphilis is a sexually transmitted disease, which has been recognized since the 16th century. T. pallidum subspecies pallidum is the etiological agent, for which there is no artificial culture media. As this infection has a variety of clinical manifestations, including a latent phase, and since there is no test that can be considered a true gold standard , it s clinical and laboratory diagnosis is sometimes rather difficult. In this thesis a number of laboratory tests for the detection the of antibodies against T. pallidum were evaluated Venereal Disease Laboratory (VDRL), Rapid Plasma Reagin (RPR), Treponema pallidum Hemaglutination Antibody (TPHA), Fluorescent Treponemal Antibody Absortion FTA-Abs), Treponema pallidum Passive Particle Agglutination Antibody (TPPA), EIA antibodies (SYPHILIS EIA) and Western blot. Molecular biology techniques were developed and optimised for the diagnosis of syphilis in different stages, including neurosyphilis. Different primers were evaluated (47-F/47-R, polA-F/polA-R-(PE), KO3A/KO4 e polA-F/polA-R) for the amplification of the 47kDa protein and DNA polimerase I gene fragments. Different types of samples were also studied - genital ulcers and skin lesions exudates, ear lobe biopsy, total blood, plasma, sera and cerebral spinal fluid (CSF) - in view of verifying in which of them the PCR technique would be more sensitive. The RPR results were identical to those obtained with the VDRL, both in blood and CSF. Therefore, it seems that the techniques can be used in either product. The results obtained with the different treponemal tests evaluated in this study were also quite similar in blood and CSF. However, some differences were found, which indicate that: a) the FTA-Abs, the Western blot and the TP.PA should be used to diagnose early phases of disease; b) the EIA test seems to be indicated when there is a high number of samples; c) the TPPA and the TPHA tests may be used in laboratory routine work and the first in following up patients; d) the FTA Abs and the Western blot are the treponemal tests that should be used preferentially for the diagnosis of neurosyphilis. On should also mentioned that the TPPA can also be used to diagnose Treponema pallidum central nervous system infection, since the results of this test were similar to those obtained with the TPHA. Co-infection with HIV seems to cause false positive results only in non - treponemal tests and that is independent of simultaneous existence of drug addiction. In relation to the PCR technique for the diagnosis of syphilis and for the different primers tried, the best results were obtained with the pair KO3/KO4. The sensitivity of both the PCR and the genotyping techniques was found to be high (100%) in genital ulcers and cutaneous lesions exudates. The same does not apply when these techniques were used in blood and cerebrospinal fluid, although when ear lobe biopsy and plasma samples were used, T. pallidum DNA was identified more often. The most frequently T. pallidum subspecies pallidum genotype found was the 14c. To our knowledge, genotype 10a was identified for the first time in this study.
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Tissot-Guerraz, Françoise. "Contribution a l'étude de la biologie des tréponématoses." Lyon 1, 1991. http://www.theses.fr/1991LYO1H096.

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Richardson, Neville John. "A comparative study of current methods for detecting treponemal antibody In selected population groups in Southern Africa." Thesis, 2015. http://hdl.handle.net/10539/19203.

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Greeff, Casparus Johannes. "Paleopathology: signs and lesions in skeletal remains of epidemics and diseases of Biblical times in Syro-Palestine." Diss., 2005. http://hdl.handle.net/10500/1958.

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This dissertation deals with the study of ancient diseases mentioned in the historical period of the Scriptures in the region of Syro-Palestine. The definition, history, methodology and etymology of the terms relating to biblical diseases are discussed. Leprosy, syphilis, plague and anaemia amongst other diseases leave skeletal signs and lesions. Paleopathologists may reveal these diseases by studying skeletal remains of the population of Syro-Palestine. Criticisms and recommendations are offered for the practical paleopathologist, anthropologist or archaeologist. More interest should be taken in the study of coprolite in every new discovery of human remains. The scarcity of skeletal remains in the region is well known. The past and present law structure, the Halakah, may partly be to blame. The future of paleopathology worldwide is undisputedly the biochemical science of DNA analysis. With this new science the role for macromorphological examination may diminish. The diseases mentioned in the Bible are finding it increasingly difficult to hide behind the words in the Scriptures.
Old Testament and Ancient Near Eastern Studies
MA (Biblical Archaeology)
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Books on the topic "Treponematoses"

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Conference, African Union against Venereal Diseases and Treponematoses Regional. 7th African Union against Venereal Diseases and Treponematoses (AUVDT) Regional Conference: STD and the community, AIDS and policies : 17-20 March 1991, Lusaka, Zambia. [Lusaka]: Zambia STD Control Programme, 1991.

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Organization, World Health, ed. WHO expert committee on venereal diseases and treponematoses: Sixth report. Geneva: World Health Organization, 1986.

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World Health Organization. Regional Office for Africa., ed. Yaws and other endemic treponematoses: Report of a Regional Meeting, Brazzaville, 3-6 February, 1986. Brazzaville: World Health Organization, Regional Office for Africa, 1986.

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African Regional Conference on Sexually Transmitted Diseases (5th 1987 Harare, Zimbabwe). Proceedings of the Fifth African Regional Conference on Sexually Transmitted Diseases, June 1st to 5th, 1987, Harare, of the African Union against Venereal Diseases and Treponematoses. Edited by Ndinya Achola J. O, Benoni B. D, and African Union against Venereal Diseases and Treponematoses. [Nairobi?]: The Union, 1987.

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Berger, Stephen, and Inc Gideon Informatics. Non-Venereal Treponematoses: Global Status. Gideon Informatics, Incorporated, 2021.

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Berger, Stephen, and Inc Gideon Informatics. Non-Venereal Treponematoses: Global Status. Gideon Informatics, Incorporated, 2022.

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Berger, Stephen, and Inc Gideon Informatics. Non-Venereal Treponematoses: Global Status. Gideon Informatics, Incorporated, 2019.

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Gideon science GIDEON science team. Non-Venereal Treponematoses: Global Status. Gideon Informatics, Incorporated, 2023.

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Cottle, Lucy, and Mike Beadsworth. Spirochaetal infection (non-syphilis). Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0312.

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Spirochaetes are slender, helical, Gram-negative rods. The group includes Treponema, Leptospira, and Borrelia. This chapter focuses on leptospirosis and Lyme disease. Discussion of the non-venereal treponematoses and relapsing fevers is beyond the scope of this text; they are rarely encountered in the UK.
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Salmon, Marylynn. Medieval Syphilis and Treponemal Disease. Bloomsbury Publishing Plc, 2022. http://dx.doi.org/10.5040/9781641899352.

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Leaders in the field of paleopathology have found enough evidence to prove that treponematosis, including syphilis, existed in ancient and medieval Afro-Eurasia, settling a decades-long debate. Yet documentary and artistic evidence to support this important work remains scarce. After summarizing the confirmed cases of treponematosis detected to date, this book turns to contemporary accounts about the death of the English king, Edward IV, that strongly indicate syphilis as the cause. It then considers further evidence suggesting contemporary awareness that elites tended to experience the disease more severely than commoners, and includes numerous examples from medical treatises and artworks that are highly suggestive that both endemic and venereal treponematosis (bejel and syphilis) were present in late medieval Europe. In doing so, the author hopes to spark a conversation not only about the existence of the disease in various places and times, but also its wider impact on premodern society and culture.
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Book chapters on the topic "Treponematoses"

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Perine, Peter L. "Nonvenereal Treponematoses." In Bacterial Infections of Humans, 733–40. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5327-4_37.

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Schaller, K. F. "Endemic Treponematoses." In Colour Atlas of Tropical Dermatology and Venerology, 63–69. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-76200-0_4.

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Padovese, Valeska. "Endemic Treponematoses." In Pigmented Ethnic Skin and Imported Dermatoses, 127–31. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-69422-1_12.

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Engelkens, Herman J. H. "Endemic Treponematoses." In Imported Skin Diseases, 162–70. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118472620.ch14.

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Perine, Peter L. "Nonvenereal Treponematoses." In Bacterial Infections of Humans, 697–705. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4757-1211-7_33.

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Luger, Anton F. H. "Endemic Treponematoses." In Sexually Transmitted Diseases, 32–58. New York, NY: Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4612-3528-6_4.

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Enenkel, Sabine, and Wolfgang Stille. "Nonvenereal Treponematoses." In Antibiotics in the Tropics, 284. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73276-8_32.

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Miller, Joseph M., and Joseph G. Pastorek. "Nonvenereal Treponematoses." In Principles of Medical Therapy in Pregnancy, 513–15. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2415-7_69.

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Naafs, Bernard. "Non-Venereal Treponematoses." In Skin Disorders in Migrants, 25–29. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-37476-1_5.

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Mikalová, Lenka, and David Šmajs. "Sexually Transmitted Treponematoses." In Diagnostics to Pathogenomics of Sexually Transmitted Infections, 211–32. Chichester, UK: John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781119380924.ch11.

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