Academic literature on the topic 'Trial Sequential Analysis'

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Journal articles on the topic "Trial Sequential Analysis"

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Leonardi-Bee, J. "Trial Sequential Analysis." International Journal of Evidence-Based Healthcare 14, no. 4 (2016): 194. http://dx.doi.org/10.1097/01.xeb.0000511335.64918.e6.

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Yang, Shengping, and Gilbert Berdine. "Trial sequential analysis." Southwest Respiratory and Critical Care Chronicles 11, no. 47 (2023): 63–67. http://dx.doi.org/10.12746/swrccc.v11i47.1175.

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Chai-Adisaksopha, Chatree, Kristian Thorlund, and Alfonso Iorio. "Interpreting trial sequential analysis." Transfusion 56, no. 12 (2016): 2918–22. http://dx.doi.org/10.1111/trf.13910.

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Kang, Hyun. "Trial sequential analysis: novel approach for meta-analysis." Anesthesia and Pain Medicine 16, no. 2 (2021): 138–50. http://dx.doi.org/10.17085/apm.21038.

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Systematic reviews and meta-analyses rank the highest in the evidence hierarchy. However, they still have the risk of spurious results because they include too few studies and participants. The use of trial sequential analysis (TSA) has increased recently, providing more information on the precision and uncertainty of meta-analysis results. This makes it a powerful tool for clinicians to assess the conclusiveness of meta-analysis. TSA provides monitoring boundaries or futility boundaries, helping clinicians prevent unnecessary trials. The use and interpretation of TSA should be based on an und
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Barakji, Jehad, Steven Kwasi Korang, Joshua Feinberg, et al. "Cannabinoids versus placebo for pain: A systematic review with meta-analysis and Trial Sequential Analysis." PLOS ONE 18, no. 1 (2023): e0267420. http://dx.doi.org/10.1371/journal.pone.0267420.

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Objectives To assess the benefits and harms of cannabinoids in participants with pain. Design Systematic review of randomised clinical trials with meta-analysis, Trial Sequential Analysis, and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Data sources The Cochrane Library, MEDLINE, Embase, Science Citation Index, and BIOSIS. Eligibility criteria for selecting studies Published and unpublished randomised clinical trials comparing cannabinoids versus placebo in participants with any type of pain. Main outcome measures All-cause mortality, pain, adverse e
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Al-Rudayni, Ali Hatem Manfi, Divya Gopinath, Mari Kannan Maharajan, Sajesh K. Veettil, and Rohit Kunnath Menon. "Efficacy of Photobiomodulation in the Treatment of Cancer Chemotherapy-Induced Oral Mucositis: A Meta-Analysis with Trial Sequential Analysis." International Journal of Environmental Research and Public Health 18, no. 14 (2021): 7418. http://dx.doi.org/10.3390/ijerph18147418.

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Oral mucositis is a debilitating complication of chemotherapy, characterized by erythema, ulcers and oedema of the oral mucosa. This review aimed to evaluate the efficacy of Photobiomodulation in the treatment of oral mucositis using meta-analysis and trial sequential analysis, and also to assess the quality of the results by Grading of Recommendations, Assessment, Development and Evaluation (GRADE). A comprehensive search of three databases, including Embase, Medline and Central, was performed to identify randomized controlled trials studying the efficacy of Photobiomodulation in the treatmen
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Alfirevic, Z., and S. Gates. "Trial sequential analysis: useful or useless?" BJOG: An International Journal of Obstetrics & Gynaecology 127, no. 10 (2020): 1227–28. http://dx.doi.org/10.1111/1471-0528.16282.

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Kulinskaya, Elena, and John Wood. "Trial sequential methods for meta-analysis." Research Synthesis Methods 5, no. 3 (2013): 212–20. http://dx.doi.org/10.1002/jrsm.1104.

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Geller, N. L. "Planned interim analysis and its role in cancer clinical trials." Journal of Clinical Oncology 5, no. 9 (1987): 1485–90. http://dx.doi.org/10.1200/jco.1987.5.9.1485.

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Although interim analyses in cancer clinical trials are commonplace, clinical trials are usually designed with the implicit assumption that data analysis will occur only after the trial is completed. The design of randomized trials with planned interim analyses, "group sequential trials," is described and examples are given. A method to redesign trials in which unplanned interim analyses have been undertaken is described. Planned interim analysis should be considered whenever a cancer clinical trial is designed.
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Maurya, Indubala, Ayush Lohiya, and Ashish Solanki. "Trial sequential analysis: Quality improvement for meta-analysis." Indian Journal of Anaesthesia 68, no. 12 (2024): 1092–94. https://doi.org/10.4103/ija.ija_1051_24.

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Dissertations / Theses on the topic "Trial Sequential Analysis"

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CASTELLINI, GRETA. "INVESTIGATING INNOVATIVE EVIDENCE SYNTHESIS METHODS: THE TRIAL SEQUENTIAL ANALYSIS, THE GRADE SYSTEM AND THE NETWORK META-ANALYSIS." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/672084.

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Le revisioni sistematiche e meta-analisi sono i migliori disegni di studio per assistere il processo decisionale in ambito clinico. Pazienti, clinici, ricercatori e decisori politici dovrebbero privilegiare la revisione sistematica rispetto a altri tipi di disegno sperimentale in quanto permette di aggregare diversi studi primari contemporaneamente, incrementando la validità interna ed esterna dei risultati. Inoltre, la meta-analisi aumenta la validità statistica raggiungendo più alti livelli di potenza statistica e precisione rispetto ai singoli studi. Ciò significa comprendere meglio la gra
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Schwimmbeck, Franz [Verfasser], and Leopold [Akademischer Betreuer] Eberhart. "Hypertone Kochsalzlösungen in der Therapie des Schädel-Hirn-Traumas und des traumatisch hämorrhagischen Schocks - Systematische Übersichtsarbeit und Metaanalyse mit Trial Sequential Analysis / Franz Schwimmbeck ; Betreuer: Leopold Eberhart." Marburg : Philipps-Universität Marburg, 2021. http://d-nb.info/1239239904/34.

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Todd, Susan Clare. "Methods of analysis for sequential clinical trials." Thesis, University of Reading, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239477.

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Morgan, Caroline Claire. "Group sequential response adaptive designs for clinical trials." Thesis, University of Sussex, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288791.

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A recently developed group-sequential response-adaptive design to compare two treatments with immediate normally distributed responses and known variances is considered. The power function of the test is the same as that under non-adaptive sampling, and significant decreases in the inferior treatment number can be achieved with only minor increases in the average sample number. Reasonably accurate corrected confidence intervals for both the treatment mean difference and the individual means are obtained by constructing approximately pivotal quantities. An approximation to the bias of the maxim
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Blatchford, Patrick Judson. "Monitoring bivariate endpoints in group sequential clinical trials /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2007.

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Thesis (Ph.D. in Biostatistics) -- University of Colorado Denver, 2007.<br>Typescript. Includes bibliographical references (leaves 104-106). Free to UCD affiliates. Online version available via ProQuest Digital Dissertations;
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Facey, Karen Maria. "Sequential procedures for clinical trials design, monitoring and analysis." Thesis, University of Reading, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315536.

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Rojas, Cordova Alba Claudia. "Resource Allocation Decision-Making in Sequential Adaptive Clinical Trials." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/86348.

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Adaptive clinical trials for new drugs or treatment options promise substantial benefits to both the pharmaceutical industry and the patients, but complicate resource allocation decisions. In this dissertation, we focus on sequential adaptive clinical trials with binary response, which allow for early termination of drug testing for benefit or futility at interim analysis points. The option to stop the trial early enables the trial sponsor to mitigate investment risks on ineffective drugs, and to shorten the development time line of effective drugs, hence reducing expenditures and expediting p
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Öhrn, Carl Fredrik. "Group sequential and adaptive methods : topics with applications for clinical trials." Thesis, University of Bath, 2011. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538283.

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This thesis deals with sequential and adaptive methods for clinical trials, and how such methods can be used to achieve efficient clinical trial designs. The efficiency gains that can be achieved through non-adaptive group sequential methods are well established, while the newer adaptive methods seek to combine the best of the classical group sequential framework with an approach that gives increased flexibility. Our results show that the adaptive methods can provide some additional efficiency, as well as increased possibilities to respond to new internal and external information. Care is howe
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Gillen, Daniel L. "The use of weighted logrank statistics in group sequential testing and non-proportional hazards /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/9557.

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Alharbi, Ghaleb. "Evidence-based medicine in neuropathic pain : a systematic review, meta-analysis, sequential analysis and network meta-analysis of randomised controlled trials." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/55427/.

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Background Many randomised controlled trials (RCTs) are available to support using different pharmacotherapy agents in the management of various neuropathic pain conditions. However, choosing these pharmacotherapy agents for neuropathic pain is challenging, due to the limited evidence-based knowledge to support the use of different pharmacotherapy agents in different neuropathic pain conditions. Aims The aim of this PhD is to evaluate the efficacy and safety of oral and topical pharmacotherapies for managing neuropathic pain by deriving placebo and active comparative efficacy and safety eviden
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Books on the topic "Trial Sequential Analysis"

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Zhong, Xiaobo. Design and Analysis of Sequential Multiple Assignment Randomized Trial for Comparing Multiple Adaptive Interventions. [publisher not identified], 2018.

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Duan-Zheng, Xu. Computer analysis of sequential medical trials. Horwood, 1990.

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Hsü, Tuan-cheng. Computer analysis of sequential medical trials. Ellis Horwood, 1990.

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Bartroff, Jay. Sequential experimentation in clinical trials: Design and analysis. Springer, 2013.

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John, Whitehead. The design and analysis of sequential clinical trials. 2nd ed. J. Wiley & Sons, 1997.

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1941-, Peace Karl E., ed. Biopharmaceutical sequential statistical applications. M. Dekker, 1992.

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Elwood, Mark. Critical appraisal of a randomized trial of a preventive agent. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199682898.003.0013.

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This chapter presents an important, large, international randomised trial of prevention, the use of folic acid and multivitamins in preventing spina bifida and other neural tube defects. This shows the ethical and logistic issues involved, a factorial randomised design, a sequential analysis and early stopping example, and specificity of effect, and discusses the application to policy. The critical assessment follows the scheme set out in chapter 10: describing the study, assessing the non-causal explanations of observation bias, confounding, and chance variation; assessing time relationships,
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Computer Analysis of Sequential Medical Trials. Prentice Hall, 1990.

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Shih, Mei-Chiung, Tze Leung Lai, and Jay Bartroff. Sequential Experimentation in Clinical Trials: Design and Analysis. Springer New York, 2015.

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The design and analysis of sequential clinical trials. 2nd ed. Ellis Horwood, 1992.

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Book chapters on the topic "Trial Sequential Analysis"

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Hall, W. Jackson. "Analysis of Sequential Clinical Trials." In Modern Clinical Trial Analysis. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4322-3_4.

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Wang, Sidi, Thomas Braun, Roy Tamura, and Kelley M. Kidwell. "Small Sample, Sequential, Multiple Assignment, Randomized Trial Design and Analysis." In Handbook of Statistical Methods for Precision Medicine. Chapman and Hall/CRC, 2024. http://dx.doi.org/10.1201/9781003216223-2.

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Shih, Weichung Joe, and Joseph Aisner. "Sequential Designs and Methods—Part III: Classical Group Sequential Trials." In Statistical Design, Monitoring, and Analysis of Clinical Trials, 2nd ed. Chapman and Hall/CRC, 2021. http://dx.doi.org/10.1201/9781003176527-9.

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Shih, Weichung Joe, and Joseph Aisner. "Sequential Designs and Methods—Part II: Monitoring Safety and Futility." In Statistical Design, Monitoring, and Analysis of Clinical Trials, 2nd ed. Chapman and Hall/CRC, 2021. http://dx.doi.org/10.1201/9781003176527-8.

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Siegmund, David. "A Retrospective of Wald’s Sequential Analysis—Its Relation to Change-point Detection and Sequential Clinical Trials." In Statistical Decision Theory and Related Topics V. Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2618-5_2.

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Shih, Weichung Joe, and Joseph Aisner. "Sequential Designs and Methods—Part I: Expected Sample Size and Two-Stage Phase II Trials in Oncology." In Statistical Design, Monitoring, and Analysis of Clinical Trials, 2nd ed. Chapman and Hall/CRC, 2021. http://dx.doi.org/10.1201/9781003176527-7.

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Schmidtke, J., and B. Schneider. "TRIQ — A PC-Program for Design and Analysis of Triangular Sequential Trials." In Compstat. Physica-Verlag HD, 1994. http://dx.doi.org/10.1007/978-3-642-52463-9_22.

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"Interim Analysis of the Helsinki Heart Study Primary Prevention Trial." In Biopharmaceutical Sequential Statistical Applications. CRC Press, 1992. http://dx.doi.org/10.1201/9781482277128-25.

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Qian, Wendi, and Philip J. Brown. "Bayes Sequential Decision Theory in Clinical Trials." In Bayesian Statistics 6. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780198504856.003.0044.

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Abstract We give a Bayesian analysis of the group sequential clinical trial to compare an experimental treatment with the standard treatment. Survival time is modelled as exponential. The trial is monitored at specified time points, either after fixed time intervals or after a fixed number of failures. The group sequential trial may consequently be modelled as a straightforward sequential trial in which survival time is the sum of exponential random variables, that is it has a gamma distribution. We use Bayes sequential decision theory to analyse the trial. The feature of this which is technic
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Li, Chen, Ping Huang, and Haitao Pan. "Introduction to Bayesian Group Sequential Design." In Clinical Trials - Recent Advances [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108852.

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In classical group sequential designs, a clinical trial is considered as a success if the experimental treatment is statistically significantly better than placebo. The criteria for stopping or continuing the trial are chosen to control the false-positive rate (type I error). Bayesian group sequential design has an advantage of allowing inclusion of prior information in the analysis. The decision criteria can be based on the posterior or predictive distribution of the treatment effect to stop for success or futility, or to continue for each interim analysis and the final analysis. This chapter
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Conference papers on the topic "Trial Sequential Analysis"

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LIU, AIYI, CHENGQING WU, and KAI F. YU. "INCORPORATING OVERRUNNING DATA INTO THE ANALYSIS OF BOTH PRIMARY AND SECONDARY ENDPOINTS IN A SEQUENTIAL TRIAL." In Random Walk, Sequential Analysis and Related Topics - A Festschrift in Honor of Yuan-Shih Chow. WORLD SCIENTIFIC, 2006. http://dx.doi.org/10.1142/9789812772558_0004.

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Zhang, Shanshan, Kun Wang, Minpeng Xu, et al. "Analysis and Classification for Single-Trial EEG Induced by Sequential Finger Movements." In 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2019. http://dx.doi.org/10.1109/embc.2019.8857117.

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Lasso Andrade, Fabricio Andres. "OP003 Magnesium sulfate in neuropathic pain: a systematic review, meta-analysis, and sequential trial analysis." In ESRA Abstracts, 41st Annual ESRA Congress, 4–7th September 2024. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/rapm-2024-esra.3.

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Sun, Fengmei, Juan Zhang, and Yuepu Pu. "Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria: A meta-analysis and trial sequential analysis." In 2ND INTERNATIONAL CONFERENCE ON MATERIALS SCIENCE, RESOURCE AND ENVIRONMENTAL ENGINEERING (MSREE 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.5005230.

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Zayed, Y., M. Banifadel, B. N. Alzghoul, et al. "Balanced Crystalloids versus Normal Saline for the Critically Ill Patients: A Meta-Analysis and Trial Sequential Analysis." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3702.

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Dhar, Jahnvi, Zaheer Nabi, Antonio Facciorusso, and Jayanta Samanta. "P141 Endoscopic ultrasound guided drainage using metal versus plastic stent for walled-off necrosis: meta-analysis of randomized trials with trial sequential analysis." In Abstracts of the BSG Annual Meeting, BSG LIVE’25, 23–26 June 2025, SEC Glasgow. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2025. https://doi.org/10.1136/gutjnl-2025-bsg.276.

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Grape, S., E. Jaunin, K. El-Boghdadly, and E. Albrecht. "ESRA19-0175 The analgesic efficacy of pecs blocks after breast surgery: a systematic review, meta-analysis and trial sequential analysis." In Abstracts of the European Society of Regional Anesthesia, September 11–14, 2019. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/rapm-2019-esraabs2019.85.

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Iltaf Satti, Danish, Yan Hiu Athena Lee, Keith Sai Kit Leung, et al. "100 Efficacy of vasopressin, steroid, and epinephrine protocol for in-hospital cardiac arrest resuscitation: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis." In British Cardiovascular Society Annual Conference, ‘100 years of Cardiology’, 6–8 June 2022. BMJ Publishing Group Ltd and British Cardiovascular Society, 2022. http://dx.doi.org/10.1136/heartjnl-2022-bcs.100.

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McConechy, Melissa K., Suzan McNamara, Mathilde Couetoux du Tertre, et al. "Abstract A07: Sequential ctDNA analysis detected preclinical relapse in patients with metastatic colorectal cancer from the Exactis trial (NCT00984048)." In Abstracts: AACR Special Conference on Advances in Liquid Biopsies; January 13-16, 2020; Miami, FL. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1557-3265.liqbiop20-a07.

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Gonvers, E., K. El-Boghdadly, S. Grape, and E. Albrecht. "39 Efficacy and safety of intrathecal morphine for analgesia after lower joint arthroplasty: a systematic review and meta-analysis with meta-regression and trial sequential analysis." In ESRA 2021 Virtual Congress, 8–9–10 September 2021. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/rapm-2021-esra.39.

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Reports on the topic "Trial Sequential Analysis"

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tian, hao. Acupuncture treatment for COPD: a trial sequential meta‑analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.12.0007.

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Li, Jia-Qi, PWH Kwong, YW Sun, WS So, and A. Sidarta. A comprehensive appraisal of meta-analyses in exercise-based stroke rehabilitation with trial sequential analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0006.

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Review question / Objective: This study aims to use the trial sequential analysis (TSA) method to examine if the published meta-analyses concerning stroke rehabilitation reached the required information size and if the overall effect size is robust as well. Condition being studied: Stroke rehabilitation. Eligibility criteria: Studies were included if they 1) were meta-analyses of random control trials (RCTs) on people with stroke, 2) included meta-analyses results in gait speed (or 6MWT) or bal-ance performance. Studies were excluded if they 1) were conference abstracts, letters to the editor
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Zhang, Yang, Qiong Xu, Feng Zhang, and Chunlei Sun. Probiotics for Preventing Neonatal Necrotizing Enterocolitis: A Meta-analysis with Trial Sequential Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.3.0124.

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Jhuang, Bo-Jyun, Bo-Han Yeh, Yen-Ta Haung, and Pei-Chun Lai. Efficacy and safety of remimazolam for procedure sedation: A meta-analysis of randomized controlled trials with trial sequential analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.8.0043.

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LI, Peng, Junhong Ren, and Yan Li. Lung ultrasound guided therapy for heart failure: an updated meta-analyses and trial sequential analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.2.0124.

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Review question / Objective: We aim to evaluate the effect of lung ultrasound (LU) guided therapy on the rates of adverse cardiac events (MACE) in heart failure (HF) patients. Condition being studied: Previous studies have found that B-lines assessed by lung ultrasound can be used for risk stratification in patients with HF and to predict the occurrence of adverse cardiac events. Therefore, similar to BNP, lung ultrasound has clinical value in guiding the management of patients with HF. However, the role of LU in guiding HF therapy is still controversial. Moreover, previous study's samples are
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Li, Jia, Jiao Huang, and Jingchen Liu. Perioperative intravenous lidocaine for postoperative pain after breast surgery: A meta-analysis with trial sequential analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.10.0033.

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Gu, Si-Chun, Li-Min Zhang, Chun-Xu Wang, et al. Chinese herbal medicines for mild cognitive impairment: A protocol for meta-analysis and trial sequential analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.9.0006.

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Qiu, Zhongming, and Chang Liu. Mechanical thrombectomy for large-core ischemic stroke: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.10.0076.

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Xiao, Chuan, Feng Shen, Yumei Cheng, and Jingjing Xiao. Timing of initiation of renal replacement therapy for acute kidney injury: a meta-analysis with trial sequential analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.12.0030.

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Kwong, PWH, Ho Ching Ng, Tsz Wan Leung, Man Hei Wong, and Jia-Qi Li. A comprehensive appraisal of meta-analyses in exercise-based upper limb stroke rehabilitation with trial sequential analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2025. https://doi.org/10.37766/inplasy2025.4.0019.

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