Academic literature on the topic 'Trials'

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Journal articles on the topic "Trials"

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Rujuta, Saksena, and M. Mehnert Janice. "Ignorance is not bliss: The importance of publishing negative trials." Biohelikon 2, no. 1 (2014): 1–3. https://doi.org/10.5281/zenodo.814311.

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It is not surprising that, in medicine, positive trials tend to generate more excitement compared with negative trials. Positive studies may be perceived as more likely to change the scope of one’s clinical practice. In general, negative studies attract less attention from different parties, including authors, editors, peer-reviewers, physicians, and readers of medical literature. Indeed, industry sponsors and principal investigators may hesitate to publish negative studies if critical acclaim of the work is not anticipated.
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Van Der Weyden, Martin B. "Trials on trial." Medical Journal of Australia 175, no. 5 (2001): 241. http://dx.doi.org/10.5694/j.1326-5377.2001.tb143553.x.

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Nelson, Mark. "Trials on trial." New Scientist 209, no. 2800 (2011): 30. http://dx.doi.org/10.1016/s0262-4079(11)60384-9.

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Vulto, Arnold G. "Clinical trials on trial." European Journal of Hospital Pharmacy 19, no. 4 (2012): 347. http://dx.doi.org/10.1136/ejhpharm-2012-000180.

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Karki, Naresh. "“Solidarity Trial”: A Feeling of Trust Towards COVID-19 Treatments." Journal of Lumbini Medical College 8, no. 1 (2020): 164–65. http://dx.doi.org/10.22502/jlmc.v8i1.335.

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Corona Virus Disease (COVID-19) drugs are not being developed at the pace in which the disease is spreading throughout the world. WHO and its partners have announced the worldwide clinical trial on 18th March 2020, known as “Solidarity Trial” for greater co-ordination of developments of drugs. “Solidarity Trialis an international clinical trial to help find an effective treatment for COVID-19”. The trial is randomized, open-label and adaptive. This trial will analyze four treatment options against standard of care, after recruiting patients from various countries, and then will approac
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Foster, Henry H. "TRIAL MARRIAGES AND DIVORCE TRIALS." Family Court Review 11, no. 1 (2005): 1–7. http://dx.doi.org/10.1111/j.174-1617.1973.tb01183.x.

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Harman, Chloë. "Putting clinical trials on trial." Nature Reviews Nephrology 5, no. 6 (2009): 301. http://dx.doi.org/10.1038/nrneph.2009.89.

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MIZUSHIMA, YUTAKA. "New trials of trial cases." Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 29, no. 1/2 (1998): 1–6. http://dx.doi.org/10.3999/jscpt.29.1.

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Palca, J. "Government ddI trials on trial." Science 246, no. 4935 (1989): 1244. http://dx.doi.org/10.1126/science.2511632.

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Moyé, Lemuel A., and Anita Deswal. "Trials within Trials." Controlled Clinical Trials 22, no. 6 (2001): 605–19. http://dx.doi.org/10.1016/s0197-2456(01)00180-5.

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Dissertations / Theses on the topic "Trials"

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Kim, Anne(Anne Y. ). "Optimizing clinical trials with Open Trial Chain." Thesis, Massachusetts Institute of Technology, 2018. https://hdl.handle.net/1721.1/121787.

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Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2019<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 59-64).<br>The objective of this thesis is to study the challenges of data sharing in healthcare (namely clinical trials), and propose the use of Open Algorithms (OPAL) as a viable solution for research collaboration that allows for access to data without compromising data ownership (data is only used once for the intended purpose, raw data is never leaked, the value gener
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Richert, Laura. "Trial design and analysis of endpoints in HIV vaccine trials." Thesis, Bordeaux 2, 2013. http://www.theses.fr/2013BOR22048/document.

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Des données complexes sont fréquentes dans les essais cliniques récents et nécessitent des méthodes statistiques adaptées. La recherche vaccinale du VIH est un exemple d’un domaine avec des données complexes et une absence de critères de jugement validés dans les essais précoces. Cette thèse d’Université concerne des recherches méthodologiques sur la conception et les aspects statistiques des essais cliniques vaccinaux du VIH, en particulier sur les critères de jugement d’immunogénicité et les schémas d’essai de phase I-II. A l’aide des données cytokiniques multiplex, nous illustrons les aspec
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Cuevas, Arriagada Ricardo Enrique, and Bustos Neil William Páez. "B-TRIALS." Tesis, Universidad de Chile, 2017. http://repositorio.uchile.cl/handle/2250/146375.

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TESIS PARA OPTAR AL GRADO DE MAGÍSTER EN ADMINISTRACIÓN<br>Ricardo Enrique Cuevas Arriagada [Parte I], Neil William Páez Bustos [Parte II]<br>El presente trabajo desarrolla una idea de negocio llamada B-Trials, cuyo origen surge a partir de una necesidad específica en la ejecución de Estudios Clínicos de la Industria Farmacéutica local, que corresponde al aumento en la participación de pacientes en la ejecución de los protocolos de estudios, a modo de aumentar la competitividad frente a los otros países de la región. Actualmente, son los médicos tratantes, colegas y/o contactos de los m
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Dias, Claire Rhiannon. "Olympic trials." Thesis, Bangor University, 2014. https://research.bangor.ac.uk/portal/en/theses/olympic-trials(feb17a88-72fb-4577-9369-810a7420399e).html.

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Olympic Trials is a literary thriller that explores the dark side of sporting culture, including the many sacrifices, dysfunctional relationships and extreme behaviours that are common aspects of participating in a high performance sport environment. Juxtaposed with the stories of the athletes, there is the tale of an aspiring terrorist. His relentless devotion to a coach-like cult leader, and his physical, spiritual and psychological struggles on his journey to the Olympic Games mirrors the challenges of the athletes. The research portion of the thesis examines many of the texts generally inc
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Loudon, Kirstine. "PRECIS-2 : making trials matter : providing an empirical basis for the selection of pragmatic design choices in clinical trials." Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/af271d88-4652-41e0-b280-4772cc30f8c4.

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Aim PRECIS (PRagmatic Explanatory Continuum Indicator Summaries 2009) is a tool with a simple wheel format that trialists can use when designing their trials to improve the applicability of results but users highlighted problems. The aim of the study was to produce an improved and validated version of PRECIS, called PRECIS-2 and test this tool out with trial teams designing primary care trials. Methods Brainstorming and a 2-round Delphi survey of authors who cited PRECIS plus user-testing of candidate PRECIS-2 models was followed by validity and reliability testing of the most promising PRECIS
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Carvajal, Luis A. Rodriguez. "Multivariate crossover trials." Thesis, University of Warwick, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336783.

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Kopec, David M., and Jeffrey J. Gilbert. "Overseeding Fairway Trials." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 2001. http://hdl.handle.net/10150/216378.

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Fifty-one overseed entries were evaluated in 1997-1998 for turfgrass performance. New experimental accessions of perennial ryegrass were darker in color than most of the commercially available germplasm included in this test. Ryegrass germplasm had better turfgrass quality after April, than did mixtures of perennial ryegrass with Poa trivialis, which performed well in December, January and March. General appearance for total plot leaf texture was best generally among the Poa trivialis containing mixtures. Hybrid (or intermediate) ryegrasses (L. which are crosses between perennial X annual ryeg
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Bartoszuk, Karin. "Randomized Control Trials." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/4161.

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Julian, Robert F. "The role of the judge and jury in complex trials." Thesis, Queen Mary, University of London, 2008. http://qmro.qmul.ac.uk/xmlui/handle/123456789/28172.

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This thesis examines the mode of trial concerns in the U.S.A., New York State, California, England and Wales and Canada --specifically the ability of the jury to comprehend complex cases and the perception/reality that bench trials may not be as fair as jury trials. Defining complex cases as those involving serious fraud indictments, capital murder trials, and lawsuits or indictments against corporations and their managers, the thesis examines problems associated with jury trials in such cases. It evaluates the comparative law and customs and practices regarding the use of juries, emphasizing
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Caldwell, Patrina Ha Yuen. "The Recruitment of Children to Randomised Controlled Trials." University of Sydney. Paediatrics and Child Health, 2003. http://hdl.handle.net/2123/579.

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Abstract Background The randomised-controlled trial (RCT) provides the best evidence for evaluating treatment effects and is accepted as a gold standard for clinical and regulatory decision making (1;2). One of the major challenges to the conduct of RCTs is the recruitment of adequate numbers of participants. Inadequate numbers reduce the power of a study to detect statistically significant treatment effects, and may cause delays, increased costs and failure to complete trials. The need for clinical trials in children has been increasingly recognised by the scientific community, result
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Books on the topic "Trials"

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Michael, Phillips, Bergman Barbara, and Oregon Criminal Defense Lawyers Association., eds. Trials and tribulations: (overcoming trial problems). [Oregon Criminal Defense Lawyers Association], 1999.

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Woodrow Wilson International Center for Scholars, ed. Rudolf Slansky: His trials and trial. Woodrow Wilson International Center for Scholars, 2008.

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Merrill, Umphrey Martha, ed. Trials. Ashgate, 2008.

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Wallach, Anne Tolstoi. Trials. Dutton, 1996.

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Merrill, Umphrey Martha, ed. Trials. Ashgate, 2008.

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Rafael, Nieves, Hayden Seitu, and Baroza Aldin, eds. Trials. SLG Pub., 1996.

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Klonoff, Robert H. Winning jury trials: Trial tactics and sponsorship strategy. 2nd ed. LexisNexis, 2002.

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Fletcher, Colin. Schools on trial: The trials of democratic comprehensives. Open University Press, 1985.

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Klonoff, Robert H. Winning jury trials: Trial tactics and sponsorship strategies. 3rd ed. National Institute for Trial Advocacy, 2007.

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Maxine, Caron, and Williams Wyn, eds. Schools on trial: The trials of democratic comprehensives. Open University Press, 1985.

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Book chapters on the topic "Trials"

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Kahn, Rebecca, Sofia S. Villar, Natalie E. Dean, and Marc Lipsitch. "22 Vaccine Trial Designs." In Principles and Practice of Emergency Research Response. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-48408-7_32.

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AbstractVaccine efficacy trials conducted during epidemics of emerging infectious diseases have three main objectives: (1) to test the null hypothesis in a rigorous fashion, (2) to estimate the efficacy of the vaccine candidate, and (3) to maximize the trial’s public health impact. All of these objectives create urgency for planning and implementing vaccine trials. Ideally, a preferred design choice, based on the anticipated aims of a trial, should be chosen as early as possible. Here we discuss five key choices that must be made in trial design: (1) randomization unit, (2) comparator interven
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Patra, Jayanta Kumar, Swagat Kumar Das, Gitishree Das, and Hrudayanath Thatoi. "Clinical Trials." In A Practical Guide to Pharmacological Biotechnology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6355-9_6.

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Basu, Bikramjit, and Sourabh Ghosh. "Clinical Trials." In Biomaterials for Musculoskeletal Regeneration. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-3017-8_9.

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"Trials." In Elgar Encyclopedia of Crime and Criminal Justice. Edward Elgar Publishing, 2023. http://dx.doi.org/10.4337/9781789902990.trials.

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Hellman, Deborah. "Trials on Trial." In Philosophical Dimensions of Public Policy. Routledge, 2017. http://dx.doi.org/10.4324/9781315126357-27.

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Weindling, Paul Julian. "Clinical Trials on Trial." In Epidemics and Genocide in Eastern Europe, 1890–1945. Oxford University Press, 2000. http://dx.doi.org/10.1093/acprof:oso/9780198206910.003.0052.

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"Trials before the Trial." In The Disappeared. Potomac Books, 2023. http://dx.doi.org/10.2307/jj.3790066.10.

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Pattenden, Rosemary. "Trial Discretions: Summary Trials." In Judicial Discretion and Criminal Litigation. Oxford University PressOxford, 1990. http://dx.doi.org/10.1093/oso/9780198255673.003.0008.

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Abstract The vast majority of criminal cases in England and Wales (around 97 per cent) go no further than the magistrates’ courts where they are dealt with summarily. If moves which are afoot to reduce the workload of the Crown Court come to fruition this high proportion may increase further. Summary trials, like trials on indictment, are adversarial, oral, and open to the public. The primary difference between the two modes of trial lies in the fusion on the bench of a magistrates’ court of the law and fact finding function, the conduct of a preliminary inquiry before a jury trial,2 and the g
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Westreich, Daniel. "Randomized Trials." In Epidemiology by Design. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190665760.003.0006.

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In Chapter 5, the author describes randomized trials. The chapter gives a broad overview of types of trials and the steps in conducting a trial and also describes how trials meet (and fail to meet) core causal identification conditions. The author provides a brief introduction to the analysis of randomized trial data. As well, the chapter introduces factorial trials as well as subgroup analysis of trials as a way of explaining differences between causal interaction and effect measure modification. Finally, the author describes issues in the generalizability and transportability of trials and q
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"Judging Sexual Assault Trials." In Putting Trials on Trial. McGill-Queen's University Press, 2018. http://dx.doi.org/10.1515/9780773553002-007.

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Conference papers on the topic "Trials"

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Jarragh, Amer, Saleh Al-Sulaiman, Srinivasan Balasundaram, Yousef Khuraibut, and Moavin Islam. "Challenges to Asset Owners During Chemical Field Trials at Operating Facilities." In CORROSION 2014. NACE International, 2014. https://doi.org/10.5006/c2014-3842.

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Abstract As part of continued efforts by an operating company to address specific corrosion mitigation needs and utilize improved integrity chemicals such as corrosion inhibitor, scale inhibitor, oxygen scavenger, biocides as well as operational chemicals such as antifoam, coagulants, anionic and cationic polyelectrolytes etc. offered by different chemical suppliers, it is necessary to conduct field trials at the existing facilities. Such chemical field trials pose specific challenges to the extent of causing even un-planned shutdown of the facilities. This paper outlines some of the typical p
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Asher, J., T. W. Conlon, B. C. Tofield, S. Sugden, and P. F. Lawrence. "Experience of Plant Corrosion Monitoring by Thin Layer Activation." In CORROSION 1986. NACE International, 1986. https://doi.org/10.5006/c1986-86131.

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Abstract A new technique for plant corrosion monitoring, Thin Layer Activation (TLA), is described. Specific trials have been carried out to develop TLA for corrosion monitoring (CM) in the offshore oil industry. Two development trials are described. In the first, standard weight-loss coupons, augmented by TLA, were installed in production wellheads and retrieved for laboratory analysis of corrosion by activity measurements; the second was a trial, on a water treatment plant, of a TLA corrosion monitor instrument system where in situ results are compared with other CM instruments operating on
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Weberski, Michael P., Claire Rayner, Dan Meier, et al. "Closed Cooling Loop Corrosion Control: Case Studies of a Reliable, Robust, & Sustainable Treatment Program." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-17723.

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Abstract Closed cooling loops are used to provide the required cooling to critical industrial equipment and processes that cannot tolerate the variability from open recirculating cooling towers. The key challenges in operating a closed loop are corrosion control and microbiological growth. A new non-toxic closed loop corrosion inhibitor program was developed that does not contain nitrite, heavy metal, P, B, or filming amine. This paper will present results from recent field trials using this new digitally-enabled, sustainable corrosion inhibitor program. The first field trial was conducted at
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Xing, Jasmine, and Ang Li. "Enhancing Clinical Trial Access and Diversity: An Innovative App for Personalized Trial Recommendations and Equitable Healthcare Participation." In 10th International Conference on Artificial Intelligence & Applications. Academy & Industry Research Collaboration Center, 2023. http://dx.doi.org/10.5121/csit.2023.131906.

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This project focuses on creating an app to recommend clinical trials to users based on their profiles, improving access and diversity in trial participation. It addresses disparities in trial representation and aims to provide easy access to trial information. The app utilizes web scraping, a recommendation system, and a saving mechanism for trials. An experiment evaluates the recommendation system's accuracy, highlighting the challenges of ethnicity clustering. The app aims to promote equitable healthcare access and expand participation in clinical trials. Shortcomings of existing solutions i
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Stubberfield, J. "ADSL trials." In IEE Seminar How Big is Your Pipe? Fast SoHo SME/Connectivity. IEE, 1999. http://dx.doi.org/10.1049/ic:19990322.

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Koulizakos, Stavros, Tina Kjellén, Karin Mellgren, and Jenny M. Kindblom. "2 Pediatric clinical trials need pediatric clinical trial budgets." In Prague 2023. 20th ESDPPP congress hosted by Prague, CZ. Our societies 20th conference and 35th anniversary. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/bmjpo-2024-esdppp.2.

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Kennedy, J., N. Sponagle, D. Wheaton, P. MacDonald, and R. Creaser. "Video Systems For Propeller Viewing Trials." In SNAME 22nd American Towing Tank Conference. SNAME, 1989. http://dx.doi.org/10.5957/attc-1989-024.

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Propeller viewing trials are a necessary adjunct to towing tank and cavitation tunnel tests, if a full assessment of propeller performance is to be made. Unfortunately, viewing trials are rare because of the expense and disruption caused by the installation of propeller viewing ports. Additionally, assessment of cavitation inception and other performance parameters is difficult because of the poor performance of the human eye under stroboscopic lighting. The Defence Research Establishment Atlantic, in conjunction with its contractors, Networx Technologies and Eyretechnics Limited, has develope
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Relton, Clare. "Randomised Controlled Trials." In HRI London 2019—Cutting Edge Research in Homeopathy: Presentation Abstracts. The Faculty of Homeopathy, 2020. http://dx.doi.org/10.1055/s-0040-1702078.

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Anderson, James, Sarah Watts, Nigel Hills, and Emmanuel Ofosu-Apeasah. "Submarine Towing Trials." In Warship 2005: Naval Submarines 8. RINA, 2005. http://dx.doi.org/10.3940/rina.ws.2005.17.

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Thatcher, K. C., B. Grant, and S. E. Welford. "RNLI Anchor Trials." In Surveillance, Pilot and Rescue Craft For The 21st Century. RINA, 1990. http://dx.doi.org/10.3940/rina.sur.1990.3.2.

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Reports on the topic "Trials"

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Border, Peter, and Samuel Bunce. Regulating Clinical Trials. Parliamentary Office of Science and Technology, 2017. http://dx.doi.org/10.58248/pn561.

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Zhang, Cheng, and Yue Yang. Impact of adaptive design on reducing the duration of clinical trials in rare cancers: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.2.0081.

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Review question / Objective: Whether the application of adaptive design in clinical trials of rare cancers can shorten the duration of clinical trials? Condition being studied: Currently, the development of innovative drug products (InMPs) for rare cancers faces many challenges, including the difficulty of enrolling sufficient numbers of patients from small and heterogeneous patient populations for clinical trials, and the significant risks of high financial investment, long development times and potential failure from a pharmaceutical company's perspective for rare cancer drugs due to limited
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Bellissant, Eric, Isabelle Boutron, Carole Chapin, et al. Ensuring that the results of all clinical trials in France are posted. Ministère de l’enseignement supérieur et de la recherche, 2025. https://doi.org/10.52949/56.

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The Working Group on “Transparency and the publicising of the results of health research”, was appointed by the French Ministry in charge of Research, in conjunction with the French Ministry in charge of Health. It seeks to address the problem of publication bias, which is the tendency to prioritise the publication of positive results. However, if they are based on an incomplete, skewed understanding of research results, this bias may result in erroneous health policy decisions. This report makes recommendations towards all stakeholders involved in clinical research, and covers the entire scie
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Kaplan, Celia P. Minorities in Clinical Trials: Patients, Physicians, Clinical Trial Characteristics, and Their Environment. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada542448.

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Kaplan, Celia. Minorities and Clinical Trials: Patients, Physicians, Clinical Trial Characteristics, and Their Environment. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada573587.

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Kaplan, Celia P. Minorities and Clinical Trials: Patients, Physicians, Clinical Trial Characteristics and their Environment. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada586285.

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Nelson, Eric. First Trials with EMPHASIS. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1660566.

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Lefebvre, Carol, and Julie Glanville. Identifying Unpublished Clinical Trial Data for Evidence Syntheses. Instats Inc., 2023. http://dx.doi.org/10.61700/txz8zyhloguql469.

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This workshop provides an overview of identifying clinical trials and trial results for systematic reviews and other evidence syntheses. It covers sources such as trials / trials results registers, regulatory agency sources, and other novel resources. Participants will learn how to search the above sources, how to manage search results and report their searches. An official Instats certificate of completion and 1 ECTS Equivalent point is provided at the conclusion of the seminar.
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Fawcett, Jim, Zack Koopman, Wayne Roush, and Josh Sievers. On-Farm Corn Rootworm Trials. Iowa State University, Digital Repository, 2015. http://dx.doi.org/10.31274/farmprogressreports-180814-1053.

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Fawcett, Jim, Lance Miller, Lyle Rossiter, et al. On-Farm Soybean Fungicide Trials. Iowa State University, Digital Repository, 2015. http://dx.doi.org/10.31274/farmprogressreports-180814-1121.

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