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Journal articles on the topic 'Triazole and tetrazole'

Author: Grafiati

Published: 6 September 2023

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1

Suresh, Lingala, P. Sagar Vijay Kumar, T. Vinodkumar, and G. V. P. Chandramouli. "Heterogeneous recyclable nano-CeO2 catalyst: efficient and eco-friendly synthesis of novel fused triazolo and tetrazolo pyrimidine derivatives in aqueous medium." RSC Advances 6, no. 73 (2016): 68788–97. http://dx.doi.org/10.1039/c6ra16307f.

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A ceria nanocatalyst was used for the one-pot, multicomponent condensation reaction of benzoylacetonitrile, aromatic aldehydes and 5-amino-triazole/tetrazole proceeding via C–C and C–N bond formation to deliver triazolo/tetrazolo[1,5-a]pyrimidines.

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2

Chandrasekhar, Attoor, Venkatachalam Ramkumar, and Sethuraman Sankararaman. "Palladium catalyzed carbonylative annulation of the C(sp2)–H bond of N,1-diaryl-1H-tetrazol-5-amines and N,4-diaryl-4H-triazol-3-amines to quinazolinones." Organic & Biomolecular Chemistry 16, no. 44 (2018): 8629–38. http://dx.doi.org/10.1039/c8ob02516a.

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Pd(ii) catalyzed direct C–H carbonylative annulation of N,1-diaryl-1H-tetrazol-5-amines and N,4-diaryl-4H-1,2,4-triazol-3-amines gave the corresponding triazole and tetrazole fused quinazolinones in good yields.

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3

Lysenko, Andrey B. "The heterobifunctional ligand 5-[4-(1,2,4-triazol-4-yl)phenyl]-1H-tetrazole and its role in the construction of a CdIImetal–organic chain structure." Acta Crystallographica Section C Crystal Structure Communications 68, no. 10 (2012): m291—m294. http://dx.doi.org/10.1107/s0108270112038498.

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5-[4-(1,2,4-Triazol-4-yl)phenyl]-1H-tetrazole, C9H7N7, (I), an asymmetric heterobifunctional organic ligand containing triazole (tr) and tetrazole (tz) termini linked directly through a 1,4-phenylene spacer, crystallizes in the polar space groupPc. The heterocyclic functions, serving as single hydrogen-bond donor (tz) or acceptor (tr) units, afford hydrogen-bonded zigzag chains with no crystallographic centre of inversion. In the structure ofcatena-poly[[diaquacadmium(II)]bis{μ2-5-[4-(1,2,4-triazol-4-yl)phenyl]tetrazol-1-ido-κ2N1:N1′}], [Cd(C9H6N7)2(H2O)2]n, (II), the CdIIdication resides on a

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4

Pavlov, Dmitry, Taisiya Sukhikh, Evgeny Filatov, and Andrei Potapov. "Facile Synthesis of 3-(Azol-1-yl)-1-adamantanecarboxylic Acids—New Bifunctional Angle-Shaped Building Blocks for Coordination Polymers." Molecules 24, no. 15 (2019): 2717. http://dx.doi.org/10.3390/molecules24152717.

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For the first time, orthogonally substituted azole-carboxylate adamantane ligands were synthesized and used for preparation of coordination polymers. The angle-shaped ligands were prepared by the reaction of 1-adamantanecarboxylic acid and azoles (1H-1,2,4-triazole, 3-methyl-1H-1,2,4-triazole, 3,5-dimethyl-1H-1,2,4-triazole, 1H-tetrazole, 5-methyl-1H-tetrazole) in concentrated sulfuric acid. Variation of the solvent and substituents in azole rings allowed to prepare both 1D and 2D copper(II) and nickel(II) coordination polymers, [Cu2(trzadc)4(H2O)0.7]∙DMF∙0.3H2O, [Cu(trzadc)2(MeOH)]∙MeOH, [Ni(

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5

Ciesielski, Witold, and Anna Krenc. "Potentiometric Titration of Triazolethiols and Tetrazolethiols with Iodine in Alkaline Medium." Collection of Czechoslovak Chemical Communications 67, no. 8 (2002): 1193–99. http://dx.doi.org/10.1135/cccc20021193.

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The iodimetric determination of triazolethiols and tetrazolethiols in alkaline medium is presented. The volumetric titration with potentiometric end-point detection was applied. The range of determination, in which the error is lower than 1%, is 20-2 000 μmol for 1H-1,2,4-triazole-3-thiol (1), 25-1 000 μmol for 3-phenyl-1H-1,2,4-triazole-5-thiol (2), 25-500 μmol for 4-methyl-5-(trifluoromethyl)-4H-1,2,4-triazole-3-thiol (3), 50-500 μmol for 3-amino-1H-1,2,4-triazole-5-thiol (4), 10-1 000 μmol for sodium (5-mercapto-1H-tetrazol-1-yl)acetate (5), 125-500 μmol for 1-phenyl-1H-tetrazole-5-thiol (6

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6

Dioukhane, Khadim, Younas Aouine, Salaheddine Boukhssas, Asmae Nakkabi, Hassane Faraj, and Anouar Alami. "Synthesis and Characterization of a Novel Biheterocyclic -amino Acid Precursor of the Triazole-Tetrazole Type, via the Copper (I) Catalyzed Alkyne-Azide Cycloaddition Reaction (CuAAC)." European Journal of Advanced Chemistry Research 2, no. 2 (2021): 7–15. http://dx.doi.org/10.24018/ejchem.2021.2.2.53.

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In this paper, we describe the regioselective synthesis of a novel tri-heterocyclic compound, a biheterocyclic amino acid precursor, derived from both triazole and tetrazole. The key step of our synthesis approach was the Huigsen 1,3-dipolar cycloaddition reaction, catalyzed by the copper (I) formed in situ by reduction of Cu(II) salts (CuSO4), 5H2O) by sodium ascorbate, and using as dipole the oxazoline azide derivative 4-(azidomethyl)-4-ethyl-2-phenyl-4,5-dihydrooxazole (4) and as dipolarophile 5-(4-methoxyphenyl)-2-(prop-2-yn-1-yl)-2H-tetrazole (3). The Cu(I) catalysis allowed us to carry o

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7

Zhao, Gang, Chunlin He, Haixiang Gao, Gregory H. Imler, Damon A. Parrish, and Jean'ne M. Shreeve. "Improving the density and properties of nitrogen-rich scaffolds by the introduction of a C–NO2 group." New Journal of Chemistry 42, no. 19 (2018): 16162–66. http://dx.doi.org/10.1039/c8nj03472a.

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5,5′-(Nitromethylene)bis(1H-tetrazole) and 5,5′-(2-(nitromethyl)-2H-1,2,3-triazole-4,5-diyl)bis(1H-tetrazole) were synthesized by introducing a C–NO<sub>2</sub> group to increase the density and detonation performance.

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8

Tiwari, Vibha, Jacob T. Bingham, Shubham Vyas, and Anand Singh. "Intermolecular fluoroamination of allenes towards substituted vinyl fluorides." Organic & Biomolecular Chemistry 18, no. 44 (2020): 9044–49. http://dx.doi.org/10.1039/d0ob01697g.

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9

Tang, Yongxing, Chunlin He, Gregory H. Imler, Damon A. Parrish, and Jean'ne M. Shreeve. "Design and synthesis of N-methylene-C linked tetrazole and nitramino-1,2,4-triazole: an approach to promising energetic materials." Journal of Materials Chemistry A 4, no. 36 (2016): 13923–29. http://dx.doi.org/10.1039/c6ta05057c.

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10

Hamdan, Fatima, Fatemeh Tahoori, and Saeed Balalaie. "Synthesis of novel cyclopeptides containing heterocyclic skeletons." RSC Advances 8, no. 59 (2018): 33893–926. http://dx.doi.org/10.1039/c8ra03899f.

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11

Yao, Zi-Xuan, Jing-Zhe Li, Hao-Hai Wang, et al. "Construction of eight mixed-valence pentanuclear CuI4Cu^II clusters using ligands with inhomogeneous electron density distribution: synthesis, characterization and photothermal properties." Dalton Transactions 51, no. 15 (2022): 6053–60. http://dx.doi.org/10.1039/d2dt00658h.

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Eight mixed-valence pentanuclear CuI4CuII clusters constructed by 1,2,3-triazole or tetrazole and different mono-phosphine ligands have been fabricated. They exhibit excellent photothermal conversion performance.

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12

Cai, Jiawei, Zhixin Li, Yanxuan Qiu, et al. "The syntheses, structures and azo–hydrazone tautomeric studies of three triazole/tetrazole azo dyes." New Journal of Chemistry 40, no. 11 (2016): 9370–79. http://dx.doi.org/10.1039/c5nj02539g.

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13

Luo, Yiming, Wanwan Zheng, Xuanjun Wang, and Fei Shen. "Nitrification Progress of Nitrogen-Rich Heterocyclic Energetic Compounds: A Review." Molecules 27, no. 5 (2022): 1465. http://dx.doi.org/10.3390/molecules27051465.

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As a momentous energetic group, a nitro group widely exists in high-energy-density materials (HEDMs), such as trinitrotoluene (TNT), 1,3,5-triamino-2,4,6-trinitrobenzene (TATB), cyclo-1,3,5-trimethylene-2,4,6-trinitramine (RDX), etc. The nitro group has a significant effect on improving the oxygen balance and detonation performances of energetic materials (EMs). Moreover, the nitro group is a strong electron-withdrawing group, and it can increase the acidity of the acidic hydrogen-containing nitrogen-rich energetic compounds to facilitate the construction of energetic ionic salts. Thus, it is

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14

Farah Smaysem and Ahmed Salim. "Synthesis and Characterization of Some Heterocyclic Compounds and Evaluation of Antibacterial Activity." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 2068–78. http://dx.doi.org/10.26452/ijrps.v11ispl4.4421.

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In this study, heterocyclic compounds with two nitrogen atoms are prepared by reaction of 2-aminobenzimidazole with formic acid to get amide derivatives (A), reacts with phenylhydrazine to get phenyl hydrazone derivatives (B), reacts with ethyl chloroacetate to obtain ethyl acetate derivatives (C). The derivative (D) obtains on heating in a basic medium. The (B) reacts with 2-chloroacetyl chloride to give derivatives (E). A number of Schiff bases are prepared (F, I) from reacting 2-aminobenzimidazole with benzaldehyde derivatives. The(F) reacts with propargyl bromide to give propargyl bromide

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15

Senthil Kumar, Kuppusamy, Bernhard Schäfer, Sergei Lebedkin, Lydia Karmazin, Manfred M. Kappes, and Mario Ruben. "Highly luminescent charge-neutral europium(iii) and terbium(iii) complexes with tridentate nitrogen ligands." Dalton Transactions 44, no. 35 (2015): 15611–19. http://dx.doi.org/10.1039/c5dt02186c.

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We report the synthesis and efficient photoluminescence of charge-neutral lanthanide (Ln = Eu<sup>3+</sup> and Tb<sup>3+</sup>) complexes based on pyrazole–pyridine–tetrazole and pyrazole–pyridine–triazole ligands.

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16

Ranjith Kumar, Gadi, Yalla Kiran Kumar, Ruchir Kant, and Maddi Sridhar Reddy. "Synthesis of benzofuranyl and indolyl methyl azides by tandem silver-catalyzed cyclization and azidation." Organic & Biomolecular Chemistry 14, no. 17 (2016): 4077–88. http://dx.doi.org/10.1039/c6ob00191b.

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A tandem Ag-catalyzed 5-exo-dig cyclization and catalyst free γ-azidation for benzofuranyl/indolyl methyl azides is presented. The adducts are further transformed to useful triazole-, tetrazole-, amide-, amine-, and pyrido-derivatives.

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17

Фролова Ю. С. та Каплаушенко А. Г. "ДОСЛІДЖЕННЯ ГОСТРОЇ ТОКСИЧНОСТІ ПОХІДНИХ 1,2,4-ТРІАЗОЛУ, ЩО МІСТЯТЬ В СВОЄМУ СКЛАДІ ЯДРО 1Н-ТЕТРАЗОЛУ". International Academy Journal Web of Scholar, № 6(36) (30 червня 2019): 23–30. http://dx.doi.org/10.31435/rsglobal_wos/30062019/6552.

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   The design of new drugs is a rather complex and multi-stage process. The modeling and creation of new biologically active compounds are one of the stages of this operation. One of the important stages of preclinical trials is the study of acute toxicity of newly synthesized compounds. Great interest in this branch is nitrogen-containing heterocycles, namely 1,2,4-triazole and their derivatives.Therefore, the purpose of our work is to study acute toxicity among new derivatives of 5-(1H-tetrazole-1-yl)-4-R-3-thio(amino)-1,2,4-triazole. The study of acute toxicity was carried

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18

Wang, Qian, Yanli Shao, and Ming Lu. "Amino-tetrazole functionalized fused triazolo-triazine and tetrazolo-triazine energetic materials." Chemical Communications 55, no. 43 (2019): 6062–65. http://dx.doi.org/10.1039/c9cc01777a.

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In this study, two insensitive energetic compounds using fused triazolo-triazine and tetrazolo-triazine as the framework, one amino and one tetrazole as functional groups, were prepared through a two-step reaction.

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19

Safin, Damir A., Antoine P. Railliet, Koen Robeyns, et al. "Complexes and salts of the nitrogen-rich triazole–tetrazole hybrid ligand with alkali and alkaline earth metal cations: experimental and theoretical findings." New Journal of Chemistry 41, no. 14 (2017): 6210–18. http://dx.doi.org/10.1039/c7nj01391d.

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20

Frolova, Yuliia, Andrii Kaplaushenko, Sameliuk Yurii, Daria Romanina, and Liubov Morozova. "nvestigation of the antimicrobial and antifungal activities of some 1,2,4-triazole derivatives." Česká a slovenská farmacie 71, no. 3 (2022): 149–58. http://dx.doi.org/10.5817/csf2022-4-149.

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This article presents the results of the study of the antimicrobial and antifungal properties among 1,2,4-triazole derivatives synthesized at the Department of Physical and Colloidal Chemistry of the Zaporizhzhia State Medical University. Previous studies have established the antimicrobial and antifungal activity of 1,2,4-triazole derivatives. Therefore, it was reasonable to investigate highly effective substances with antimicrobial and antifungal properties among synthesized compounds. In the first stage of our research, acute toxicity prediction was performed. The antimicrobial and antifunga

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21

Sun, Han-Xu, Jie Zhou, Zhen Zhang, et al. "Anion-controlled Zn(ii) coordination polymers with 1-(tetrazo-5-yl)-3-(triazo-1-yl) benzene as an assembling ligand: synthesis, characterization, and efficient detection of tryptophan in water." Dalton Transactions 50, no. 48 (2021): 18044–52. http://dx.doi.org/10.1039/d1dt03045k.

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The triazole/tetrazole N-donor ligand of Httb is rarely studied in the construction of CPs. A controlling effect of anions on supramolecular architectures has been observed. CP 2 has been proved to be the best tryptophan sensor.

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22

Song, Wu-Hui, Ming-Ming Liu, Dong-Wei Zhong, et al. "Tetrazole and triazole as bioisosteres of carboxylic acid: Discovery of diketo tetrazoles and diketo triazoles as anti-HCV agents." Bioorganic & Medicinal Chemistry Letters 23, no. 16 (2013): 4528–31. http://dx.doi.org/10.1016/j.bmcl.2013.06.045.

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23

Kizhnyaev, V. N., F. A. Pokatilov, and L. I. Vereshchagin. "Carbochain polymers with oxadiazole, triazole, and tetrazole cycles." Polymer Science Series C 50, no. 1 (2008): 1–21. http://dx.doi.org/10.1134/s1811238208010013.

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24

Begtrup, Mikael. "ChemInform Abstract: Diazole, Triazole, and Tetrazole N-Oxides." ChemInform 43, no. 45 (2012): no. http://dx.doi.org/10.1002/chin.201245258.

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25

Fei, Teng, Yao Du, and Siping Pang. "Theoretical design and prediction of properties for dinitromethyl, fluorodinitromethyl, and (difluoroamino)dinitromethyl derivatives of triazole and tetrazole." RSC Advances 8, no. 19 (2018): 10215–27. http://dx.doi.org/10.1039/c8ra00699g.

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Twelve series of –CH(NO<sub>2</sub>)<sub>2</sub>, –CF(NO<sub>2</sub>)<sub>2</sub>and –C(NF<sub>2</sub>)(NO<sub>2</sub>)<sub>2</sub>substituted derivatives of triazole and tetrazole were designed, some physicochemical or detonation properties of them were calculated.

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26

Tinant, Bernard, Anil D. Naik, Mathieu Monaux, and Yann Garcia. "Engineering metal-organic frameworks with a triazole-tetrazole ligand." Acta Crystallographica Section A Foundations of Crystallography 66, a1 (2010): s246—s247. http://dx.doi.org/10.1107/s0108767310094407.

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27

Maddila, Suresh, Ramakanth Pagadala, and Sreekanth B. Jonnalagadda. "Synthesis and Insecticidal Activity of Tetrazole-Linked Triazole Derivatives." Journal of Heterocyclic Chemistry 52, no. 2 (2014): 487–91. http://dx.doi.org/10.1002/jhet.2078.

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28

Rowlett, Roger S., Thomas Klysa, and William W. Shiraki. "Synthesis of tetrazole-13C and 1,2,4-triazole-1,2-15N2." Journal of Labelled Compounds and Radiopharmaceuticals 28, no. 12 (1990): 1437–40. http://dx.doi.org/10.1002/jlcr.2580281212.

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29

Sakakibara, Jinsaku, Shin-ichi Nagai, Naoki Kato, Taisei Ueda, and Noriichi Oda. "Bridgehead Nitrogen Heterocycles. Synthesis of Methanoazepines Fused with Tetrazole, 1,2,4-Triazole and 1,2,4-Triazine." HETEROCYCLES 24, no. 4 (1986): 907. http://dx.doi.org/10.3987/r-1986-04-0907.

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30

Nevonen, Dustin E., Laura S. Ferch, Victor Y. Chernii, David E. Herbert, Johan van Lierop, and Victor N. Nemykin. "X-Ray structures, Mössbauer hyperfine parameters, and molecular orbital descriptions of the phthalocyaninato iron(II) azole complexes." Journal of Porphyrins and Phthalocyanines 24, no. 05n07 (2020): 894–903. http://dx.doi.org/10.1142/s1088424619502043.

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The electronic structures of a set of PcFe(azole)2 complexes (azole = imidazole, [Formula: see text]-methylimidazole, pyrazole, isoxazole, thiazole, 1,2,4-triazole, 3-amino-1,2,4,-triazole, and 5-amino-1,2,3,4-tetrazole) were examined by Mössbauer spectroscopy and Density Functional Theory (DFT) calculations. In addition, the geometric distortions in these compounds were elucidated by X-ray crystallography for imidazole, pyrazole, and thiazole-containing compounds. Predicted by DFT calculations, Mössbauer hyperfine parameters for all compounds are in reasonable agreement with experimental resu

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31

Xiong, Guolin, Zhichao Liu, Qiong Wu, Weihua Zhu, and Heming Xiao. "Theoretical study of energetic carbon-oxidized triazole and tetrazole derivatives." Canadian Journal of Chemistry 93, no. 3 (2015): 368–74. http://dx.doi.org/10.1139/cjc-2014-0363.

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We investigated the heat of formation, density, thermal stability, and detonation properties of a series of carbon-oxidized triazole and tetrazole derivatives substituted by –NH2 and –NO2 groups using density functional theory. It is found that their properties are associated with the numbers of substituents and substitution positions in the parent ring. The results show that the –NO2 group is an effective structural unit for enhancing their detonation performance. It also indicates that the substitution positions play a very important role in increasing the heat of formation values of the der

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32

Vereshchagin, L. I., V. N. Kizhnyaev, O. N. Verkhozina, A. G. Proidakov, and A. I. Smirnov. "Synthesis of Polycyclic Functionally-substituted Triazole- and Tetrazole-containing Systems." Russian Journal of Organic Chemistry 40, no. 8 (2004): 1156–61. http://dx.doi.org/10.1023/b:rujo.0000045898.10072.7f.

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33

Vereshchagin, L. I., A. V. Petrov, A. G. Proidakov, F. A. Pokatilov, A. I. Smirnov, and V. N. Kizhnyaev. "Polynuclear nonfused tetrazole-, 1,3,4-oxadiazole-, and 1,2,3-triazole-containing systems." Russian Journal of Organic Chemistry 42, no. 6 (2006): 912–17. http://dx.doi.org/10.1134/s1070428006060170.

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34

Frey, Guido D., Karl Öfele, Herbert G. Krist, Eberhardt Herdtweck, and Wolfgang A. Herrmann. "Tetrazole and triazole carbene complexes of group 6 metal carbonyls." Inorganica Chimica Acta 359, no. 9 (2006): 2622–34. http://dx.doi.org/10.1016/j.ica.2005.09.049.

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35

Kizhnyaev, Valerii N., Tat’yana V. Golobokova, Fedor A. Pokatilov, Leontii I. Vereshchagin, and Yakov I. Estrin. "Synthesis of energetic triazole- and tetrazole-containing oligomers and polymers." Chemistry of Heterocyclic Compounds 53, no. 6-7 (2017): 682–92. http://dx.doi.org/10.1007/s10593-017-2109-6.

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36

Yadav, Abhishek Kumar, Vikas D. Ghule, and Srinivas Dharavath. "Dianionic nitrogen-rich triazole and tetrazole-based energetic salts: synthesis and detonation performance." Materials Chemistry Frontiers 5, no. 24 (2021): 8352–60. http://dx.doi.org/10.1039/d1qm01365c.

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To develop explosives with excellent stability, and detonation performance, a series of nitrogen-rich salts were synthesized from 5,5′-methylenebistetrazolate and N,N′-(methylenebis(1H-1,2,4-triazole-3,5-diyl))dinitramide.

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37

Malek, Fouad, Tarik Harit, Mounir Cherfi, and Bonglee Kim. "Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties." Molecules 27, no. 7 (2022): 2123. http://dx.doi.org/10.3390/molecules27072123.

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Macrocyclic chemistry has been extensively developed over the past several decades. In fact, the architecture of new macrocyclic models has undergone exponential growth to offer molecules with specific properties. In this context, an attempt is made in this study to provide an overview of some synthetic methods allowing the elaboration of N-heterocycles containing macrocycles (imidazole, triazole, tetrazole, and pyrazole), as well as their applications in the complexation of metal cations or as pharmacological agents.

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38

Wang, Xiuli, Xue Bai, Hongyan Lin, Junjun Sun, Guocheng Liu, and Xiang Wang. "Novel polyoxometalate-based cobalt complexes based on rigid pyridyl-triazole-tetrazole and pyridyl-bis(triazole) ligands." CrystEngComm 20, no. 41 (2018): 6438–48. http://dx.doi.org/10.1039/c8ce01158c.

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Three novel polyoxometalate (POM)-based cobalt complexes have been synthesized and structurally characterized. The adsorption activities for organic dyes and electrochemical properties have been studied in detail.

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39

Schollmeyer, Dieter, and Heiner Detert. "3-(4-Hexyloxyphenyl)-1,2,4-triazolo[3,4-b]benzothiazole." Acta Crystallographica Section E Structure Reports Online 70, no. 3 (2014): o247. http://dx.doi.org/10.1107/s1600536814002153.

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The title compound, C20H21N3OS, was prepared by Huisgen reaction of 5-(4-hexyloxyphenyl)tetrazole and chlorobenzothiazole. The essentially planar benzothiazolotriazole framework [maximum deviation from the mean plane of 0.077 (1) Å for the bridgehead N atom] and the phenyl ring form a dihedral angle of 53.34 (5)°. The hexyloxy chain adopts agauche–all-anti conformation. The intracentroid separation of 3.7258 (8) Å between the triazole and benzene rings is the closest contact between individual molecules in the crystal.

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40

Ruma, Yasmeen N., Mikhail V. Keniya, Joel D. A. Tyndall, and Brian C. Monk. "Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host." Journal of Fungi 8, no. 1 (2022): 69. http://dx.doi.org/10.3390/jof8010069.

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The fungal cytochrome P450 lanosterol 14α-demethylase (CYP51) is required for the biosynthesis of fungal-specific ergosterol and is the target of azole antifungal drugs. Despite proven success as a clinical target for azole antifungals, there is an urgent need to develop next-generation antifungals that target CYP51 to overcome the resistance of pathogenic fungi to existing azole drugs, toxic adverse reactions and drug interactions due to human drug-metabolizing CYPs. Candida parapsilosis is a readily transmitted opportunistic fungal pathogen that causes candidiasis in health care environments

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41

Wang, Shiben, Hui Liu, Xuekun Wang, Kang Lei, Guangyong Li, and Zheshan Quan. "Synthesis and Evaluation of Antidepressant Activities of 5-Aryl-4,5-dihydrotetrazolo [1,5-a]thieno[2,3-e]pyridine Derivatives." Molecules 24, no. 10 (2019): 1857. http://dx.doi.org/10.3390/molecules24101857.

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In this study, we synthetized a series of 5-aryl-4,5-dihydrotetrazolo[1,5-a]thieno[2,3-e]pyridine derivatives containing tetrazole and other heterocycle substituents, i.e., triazole, methyltriazole, and triazolone. The forced swim test (FST) and tail suspension test (TST) were used to evaluate the antidepressant activity of the target compounds. The compound 5-[4-(trifluoromethyl)phenyl]-4,5-dihydrotetrazolo[1,5-a]thieno[2,3-e]pyridine (4i) showed the highest antidepressant activity, with a reduced immobility time of 55.33% when compared with the control group. Using an open-field test, compou

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42

Shin, Jung-Ah, Yeong-Gweon Lim, and Kyung-Hee Lee. "Synthesis of Polymers Including Both Triazole and Tetrazole by Click Reaction." Bulletin of the Korean Chemical Society 32, no. 2 (2011): 547–52. http://dx.doi.org/10.5012/bkcs.2011.32.2.547.

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43

Jenkins, Sarah M., Harry J. Wadsworth, Steven Bromidge, et al. "Substituent variation in azabicyclic triazole- and tetrazole-based muscarinic receptor ligands." Journal of Medicinal Chemistry 35, no. 13 (1992): 2392–406. http://dx.doi.org/10.1021/jm00091a007.

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Burasov, A. V., T. S. Vakhotina, and V. A. Petrosyan. "Indirect Electrochemical N-Dimethoxyphenylation of 3-Nitro-1,2,4-triazole and Tetrazole." Russian Journal of Electrochemistry 41, no. 8 (2005): 903–7. http://dx.doi.org/10.1007/s11175-005-0154-4.

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Kato, Yuki, Masayuki Ninomiya, Yuji Yamaguchi, and Mamoru Koketsu. "Synthesis of triazole- and tetrazole-xyloside analogues as potent hyaluronidase inhibitors." Medicinal Chemistry Research 24, no. 3 (2014): 1180–88. http://dx.doi.org/10.1007/s00044-014-1203-x.

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Srinivas, Dharavath, Vikas D. Ghule, and Krishnamurthi Muralidharan. "Synthesis of nitrogen-rich imidazole, 1,2,4-triazole and tetrazole-based compounds." RSC Advances 4, no. 14 (2014): 7041. http://dx.doi.org/10.1039/c3ra47227b.

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Maier, Günther, Jürgen Eckwert, Axel Bothur, Hans Peter Reisenauer, and Christiane Schmidt. "Photochemical Fragmentation of Unsubstituted Tetrazole, 1,2,3-Triazole, and 1,2,4-Triazole: First Matrix-Spectroscopic Identification of Nitrilimine HCNNH." Liebigs Annalen 1996, no. 7 (2006): 1041–53. http://dx.doi.org/10.1002/jlac.199619960704.

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48

Al-Ghorbani, Mohammed, Osama Alharbi, Abdel-Basit Al-Odayni та Naaser A. Y. Abduh. "Quinoline- and Isoindoline-Integrated Polycyclic Compounds as Antioxidant, and Antidiabetic Agents Targeting the Dual Inhibition of α-Glycosidase and α-Amylase Enzymes". Pharmaceuticals 16, № 9 (2023): 1222. http://dx.doi.org/10.3390/ph16091222.

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Novel analogs of quinoline and isoindoline containing various heterocycles, such as tetrazole, triazole, pyrazole, and pyridine, were synthesized and characterized using FT-IR, NMR, and mass spectroscopy, and their antioxidant and antidiabetic activities were investigated. The previously synthesized compound 1 was utilized in conjugation with ketone-bearing tetrazole and isoindoline-1,3-dione to synthesize Schiff’s bases 2 and 3. Furthermore, hydrazide 1 was treated with aryledines to provide pyrazoles 4a–c. Compound 5 was obtained by treating 1 with potassium thiocyanate, which was then cycli

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El-Azhary, A. A., H. U. Suter, and J. Kubelka. "Experimental and Theoretical Investigation of the Geometry and Vibrational Frequencies of 1,2,3-Triazole, 1,2,4-Triazole, and Tetrazole Anions." Journal of Physical Chemistry A 102, no. 3 (1998): 620–29. http://dx.doi.org/10.1021/jp9719568.

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GUO, Yunyun, and Zhiwen YE. "Progress in Synthesis of Energetic Ionic Salts of Triazole and Tetrazole Compounds." Acta Agronomica Sinica 30, no. 5 (2013): 489. http://dx.doi.org/10.3724/sp.j.1095.2013.20261.

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