Log in

Relevant bibliographies by topics / Triazolo-thiadiazole

Contents

Journal articles
Book chapters

Academic literature on the topic 'Triazolo-thiadiazole'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Triazolo-thiadiazole.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Triazolo-thiadiazole"

1

Myrko, Iryna I. "Synthesis and Anti-inflammatory Activity of Some New 6-Aryltriazolo[3,4-b][1,3,4]thiadiazole Derivatives." Journal of Organic and Pharmaceutical Chemistry 22, no. 4 (2024): 17–24. https://doi.org/10.24959/ophcj.24.321751.

Full text

Abstract:

A series of 6-aryl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives has been synthesized. Their anti-inflammatory activity has been studied in vivo in a carrageenan model of the paw inflammatory edema in rats. 3-(2-Fluorophenyl)-6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (3c) and 3-(2-fluorophenyl)-6-(4-methoxy-phenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (3d) have been identified as hit compounds with the anti-exudative activity. The crucial role of the fluorine atom in the anti-inflammatory activity has been determined, which value considerably correlates with the calculated val

APA, Harvard, Vancouver, ISO, and other styles

2

Lelyukh, Maryan, Arkady Savchenko, Myroslava Kalytovska, et al. "Pharmacological profile of condensed heterocyclic compounds based on functionally substituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles: A review." Current Chemistry Letters 14, no. 3 (2025): 567–78. https://doi.org/10.5267/j.ccl.2025.3.001.

Full text

Abstract:

Triazolo[3,4-b][1,3,4]thiadiazole molecules are found to be important tools in modern bioorganic and medicinal chemistry. This condensed system successfully combines two pharmacologically significant five-membered heterocycles – 1,2,4-triazole and 1,3,4-thiadiazole, which causes much more interest in the enhanced activity profile of its analogs than their parent separate constituents. It’s considered that the triazoles fused to thiadiazoles exhibit various therapeutically important properties, probably due to the existence of N-C-S fragments in their structures. In this review, we presented th

APA, Harvard, Vancouver, ISO, and other styles

3

EL-Mahdy, Ahmed F. M., Hassan A. H. EL-Sherief, Zeinab A. Hozien, and Shiao-Wei Kuo. "A Convenient One-Pot and Rapid Microwave-Assisted Synthesis of Biologically Active s-Triazolo[3,4-b][1,3,4]Thiadiazine and s-Triazolo[3,4-b][1,3,4]Thiadiazole Nanoarchitectonics." Journal of Nanoscience and Nanotechnology 20, no. 5 (2020): 2917–29. http://dx.doi.org/10.1166/jnn.2020.17452.

Full text

Abstract:

A rapid and efficient one-pot protocol has been developed for the synthesis of s-triazolo[3,4-b][1,3,4]thiadiazine and s-triazolo[3,4-b][1,3,4]thiadiazole nanoarchitectonics through the reaction of s-triazoles with ketones and nitriles in acetic acid containing a catalytic amount of sulfuric acid under microwave irradiation in excellent yields. With this catalytic reaction, the cheap sulfuric acid as well as other acids were examined as catalysts and the highly toxic and irritating haloketones and halonitriles were avoided to form. The effects of microwave power, temperature, time, solvent and

APA, Harvard, Vancouver, ISO, and other styles

4

El-Sayed, Wael A., Omar M. Ali, Marwa M. Hathoot, and Adel A. H. Abdel-Rahman. "Synthesis and Antimicrobial Activity of New Substituted Fused 1,2,4-Triazole Derivatives." Zeitschrift für Naturforschung C 65, no. 1-2 (2010): 22–28. http://dx.doi.org/10.1515/znc-2010-1-204.

Full text

Abstract:

A number of new substituted 1,2,4-triazole, 1,2,4-triazolo[3,4-b]1,3,4-thiadiazole and 1,2,4-triazolo[3,4-b]1,3,4-thiadiazine derivatives were synthesized and tested for their antimicrobial activity against Bacillus subtilis (Gram-positive), Pseudomonas aeruginosa (Gramnegative), and Streptomyces species (Actinomycetes). The synthesized compounds displayed different degrees of antimicrobial activities or inhibitory actions.

APA, Harvard, Vancouver, ISO, and other styles

5

Vaarla, Krishnaiah, V. Rajeswar Rao, and Mehmet Akkurt. "Crystal structure of 3-benzylsulfanyl-6-(5-methyl-1,2-oxazol-3-yl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole." Acta Crystallographica Section E Crystallographic Communications 71, no. 11 (2015): o809—o810. http://dx.doi.org/10.1107/s2056989015017351.

Full text

Abstract:

In the title compound, C14H11N5OS2, the triazolo–thiadiazole system is essentially planar (r.m.s. deviation = 0.002 Å) and makes dihedral angles of 6.33 (12) and 42.95 (14)° with the planes of the oxazole and phenyl rings, respectively. In the crystal, face-to-face π–π interactions are observed between the thiadiazole and oxazole rings [centroid–centroid distance = 3.4707 (18) Å], leading to columns along [010].

APA, Harvard, Vancouver, ISO, and other styles

6

SANGEETA, SUDAN, GUPTA RAJIVE, and L. KACHROO P. "Bridgehead Nitrogen Heterocycles : Synthesis and Biological Activities of s-Triazolo[3,4-b] [1,3,4]thiadiazole System." Journal of Indian Chemical Society Vol. 73, Nov 1996 (1996): 625–26. https://doi.org/10.5281/zenodo.5918317.

Full text

Abstract:

Department of Chemistry, University of Jammu, Jammu-180 004 <em>Manuscript received 27 September 1994, revived 10 March 1995, accepted 15 March 1995</em> Bridgehead Nitrogen Heterocycles : Synthesis and Biological Activities of <em>s</em>-Triazolo[3,4-b] [1,3,4]thiadiazole System.

APA, Harvard, Vancouver, ISO, and other styles

7

Trafalis, Dimitrios T., Sofia Sagredou, Panayiotis Dalezis, et al. "Anticancer Activity of Triazolo-Thiadiazole Derivatives and Inhibition of AKT1 and AKT2 Activation." Pharmaceutics 13, no. 4 (2021): 493. http://dx.doi.org/10.3390/pharmaceutics13040493.

Full text

Abstract:

The fusion of 1,2,4-triazole and 1,3,4-thiadiazole rings results in a class of heterocycles compounds with an extensive range of pharmacological properties. A series of 1,2,4-triazolo[3,4-b]-1,2,4-thiadiazoles was synthesized and tested for its enzyme inhibition potential and anticancer activity. The results show that 1,2,4-triazolo[3,4-b]-1,2,4-thiadiazoles display potent anticancer properties in vitro against a panel of cancer cells and in vivo efficacy in HT-29 human colon tumor xenograft in CB17 severe combined immunodeficient (SCID) mice. Preliminary mechanistic studies revealed that KA25

APA, Harvard, Vancouver, ISO, and other styles

8

Nagaraju, Tumula, Palakodety Radha Krishna, Balasubramanian Sridhar, and Nakka Mangarao. "PhI(OAc)2-Mediated Regioselective Synthesis of 5-Guanidino-1,2,4-thiadiazoles and 1,2,4-Triazolo[1,5-a]pyridines via Oxidative N–S and N–N Bond Formation." Synthesis 51, no. 19 (2019): 3600–3610. http://dx.doi.org/10.1055/s-0037-1611854.

Full text

Abstract:

An effective and expeditious approach for the construction of biologically important 5-guanidino-1,2,4-thiadiazole and 1,2,4-triazolo[1,5-a]pyridine derivatives has been developed. This new protocol involves the phenyliodine(III) diacetate [PhI(OAc)2]-mediated oxidative cyclization of thioureas/2-aminopyridines and imidates via N–S and N–N bond formation at ambient temperature. This method furnishes the versatile 5-guanidino-1,2,4-thiadiazoles and 1,2,4-triazolo[1,5-a]pyridines in a scalable manner with high efficiency and excellent regioselectivity.

APA, Harvard, Vancouver, ISO, and other styles

9

P., D. SINGH, and K. MISHRA L. "Complexes of 2,4-Dimercapto-s triazolo[4,3-b]- 1,3,4-thiadiazole with some Platinum Metal Ions. Part-II." Journal of Indian Chemical Society Vol. 65, Jun 1988 (1988): 447–48. https://doi.org/10.5281/zenodo.6303500.

Full text

Abstract:

Department of Chemistry, Patna University, Patna-800 005 <em>Manuscript received </em><em>10 February</em> <em>1988, </em><em> accepted 25 March 1988</em> Complexes of 2,4-Dimercapto-s triazolo[4,3-b]- 1,3,4-thiadiazole with some Platinum Metal Ions. Part-II.

APA, Harvard, Vancouver, ISO, and other styles

10

Lelyukh, Maryan, Andriy Paliy, Maria Zhukrovska, et al. "A review on synthetic approaches for obtaining and chemical modification of 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole based heterocyclic compounds." Current Chemistry Letters 13, no. 4 (2024): 737–52. http://dx.doi.org/10.5267/j.ccl.2024.3.007.

Full text

Abstract:

Triazolo[3,4-b]thiadiazoles are a class of heterocyclic compounds, which have attracted great interest in medicinal chemistry owing to their wide range of pharmacological activities. A number of triazoles fused to thiadiazoles are incorporated into a wide variety of therapeutically important compounds possessing a broad spectrum of biological activities. Considering such a significant pharmacological potential, as well as wide synthetic possibilities triazolo-thiadiazoles have received considerable attention from scientiﬁc community and are extensively used for construction of prospective drug

APA, Harvard, Vancouver, ISO, and other styles

More sources

Book chapters on the topic "Triazolo-thiadiazole"

1

"3-Oxa-6,7,8-triazabicyclo[3.3.0]oct-6-ene to 5H-1,2,3-Triazolo[4,5-c]-1λ4,2,5-thiadiazole." In Substance Index, edited by Backes, Fröhlich, and Padeken. Georg Thieme Verlag, 2000. http://dx.doi.org/10.1055/b-0035-114018.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!